JournalTOCs

Journal of Biophysics and Structural Biology
Number of Followers: 3

This is an Open Access Journal

Open Access journal
ISSN (Online) 2141-2200
Published by Academic Journals

[33 journals]

Evaluation of toxicity of copper oxide nano particles on human blood
- Abstract: Copper oxide (CuO) nanoparticles are of incredible interest because of its efficacious applications including electronic devices, optoelectronic devices, such as microelectromechanical frameworks, field effect transistors, electrochemical cells, gas sensors, magnetic storage media, sun-powered cells, field emitters and nanodevices (for catalysis and medical applications). Examination by Tran...
  PubDate: Sun, 31 Jan 2021 00:00:00 +010
Synthesis and Characterization of Iron Oxide Nanoparticles from Wonderful
Kola seed for Future Application in Microwave Tumour Ablation
- Abstract: The green method of synthesizing nanoparticles is an eco-friendly, reliable and cost effective approach which has proven to be an alternative to chemical based methods over the years (Dipankar and Murugan, 2012). This research focuses on the synthesis and characterization of super-paramagnetic iron oxide nanoparticles (FeNPs), adopted a co-precipitation procedure by the interaction of ferric...
  PubDate: Sun, 31 Jan 2021 00:00:00 +010
Physical basis of the DNA double helix
- Abstract: Despite the widely spread acceptance that the enthalpy of DNA duplex unfolding does not depend on temperature and is greater for the CG base pair held by three hydrogen bonds than for the AT base pair held by only two hydrogen bonds, direct calorimetric measurement has shown that the enthalpic and entropic contributions of both base pairs are temperature dependent and at all temperatures the...
  PubDate: Fri, 31 Jan 2020 00:00:00 +010
Extrapolating human toxicity data with target organ dose (TOD-Wb) model: A
meso-scale allometric analytical approach
- Abstract: An allometric target organ dose model (TOD-Wb) with variable scaling exponent, b = br + bo(bm) - bi, is proposed for the extrapolation of animal toxicity to human. The exponent b comprises four constituent parameters representing the intake mode to entry organ (bi), route of transportation to target organ (br), mass of target organ (bo), and rate of metabolism at target organ (bm). This expr...
  PubDate: Sat, 30 Sep 2017 00:00:00 +010
Spectroscopic approach of the interaction study of ceftriaxone and human
serum albumin
- Abstract: Under physiological conditions, interaction between ceftriaxone and human serum albumin was investigated by using fluorescence spectroscopy and ultra violet (UV) absorption spectrum. From spectral analysis, ceftriaxone showed a strong ability to quench the intrinsic fluorescence of human serum albumin (HSA) through a static quenching procedure. The binding constant (k) is estimated as K=1.02...
  PubDate: Fri, 28 Feb 2014 00:00:00 +010
Changes in airway resistance with cumulative numbers of cigarettes smoked
- Abstract: This work was performed with smokers of Virginia tobacco cigarettes without taking into consideration brand or type of cigarettes. An experimental study was conducted for the variation of cigarettes number and the increments in airway resistance for both normal and respiratory disordered subjects using body plethysmograph for testing individuals. Seventeen (17) nonsmokers and ten smokers wer...
  PubDate: Wed, 31 Jul 2013 00:00:00 +010
Epigenetic regulation of PGC1 Î± in human type 2 diabetes
- Abstract: Type 2 diabetes mellitus (T2DM) is the most common metabolic disease in theworld, reaching epidemic proportions. PPARGC1A mRNA expression is reduced in islets from patients with diabetes 2 and it is influenced by both genetic and epigenetic factor. The epigenetic modification, results as a two fold increase in DNA methylation of the PGC1A promoter of diabetes. This two fold increase in DNA m...
  PubDate: Wed, 31 Jul 2013 00:00:00 +010
Using electrical impedance tomography in following up skin conductivity
change for different sonophoresis conditions
- Abstract: Sonophoresis is the using of ultrasound waves to increase the entrancement of genes and drugs surpassing the skin barrier. Many mechanisms have been described to illustrate the sonophoresis mode of action; some describe changes in skin resistance during sonophoresis. Electrical impedance tomography (EIT) technique uses voltage measurement through a group of electrodes and reconstructs the da...
  PubDate: Sat, 31 Mar 2012 00:00:00 +010
The use of a continuity equation of fluid mechanics to reduce the
abnormality of the cardiovascular system: A control mechanics of the human
heart
- Abstract: The paper is aimed at presenting the differential equations for the cardiovascular system with the help of continuity equation of fluid mechanics to reduce the abnormality of the rate of blood flow and variation of blood volume in different parts of the system. The equations are used to explain the Frank-Starling mechanism, which plays an important role in the maintenance of the stability of...
  PubDate: Sat, 31 Mar 2012 00:00:00 +010
pH uniquely modulates protein arginine methylation
- Abstract: Protein arginine methyltransferases (PRMTs) function in the alkaline milieu of the nucleus and at neutral pH of the cytosol. Accordingly, several PRMTs are broadly active over a range of pHs. We investigated the effect altering pH had on protein arginine methylation using a variety of defined substrates, recombinant PRMTs and cell extracts.We demonstrate that pH-induced alterations in the ex...
  PubDate: Wed, 30 Nov 2011 00:00:00 +010