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Journal Cover JAMA The Journal of the American Medical Association
  [SJR: 6.278]   [H-I: 491]   [1052 followers]  Follow
   Full-text available via subscription Subscription journal
   ISSN (Print) 0098-7484 - ISSN (Online) 1538-3598
   Published by American Medical Association Homepage  [11 journals]
  • Screening for Depression in Adults
    • Authors: Siu AL; , Bibbins-Domingo K, et al.
      Abstract: This Recommendation Statement from the US Preventive Services Task Force recommends screening for depression in the general adult population, including pregnant and postpartum women, with adequate systems in place to ensure accurate diagnosis, effective treatment, and appropriate follow-up.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Depression Screening and Treatment in Pregnant and Postpartum Women
    • Abstract: This systematic review to support the 2016 US Preventive Services Task Force Recommendation Statement on screening for depression summarizes trial evidence about depression screening, treatment, and accuracy of screening instruments in pregnant and postpartum women.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Analyzing Repeated Measurements Using Mixed Models
    • Authors: Detry MA; Ma Y.
      Abstract: This Guide to Statistics and Methods discusses analyzing repeated measurements using mixed models.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Immunotherapies and Outcomes in Relapsing-Remitting Multiple Sclerosis
    • Authors: Tramacere I; Del Giovane C, Filippini G.
      Abstract: This Clinical Evidence Synopsis summarizes a Cochrane review on the efficacy of immunotherapies for multiple sclerosis.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Safety of Propranolol Therapy for Severe Infantile Hemangioma
    • Authors: Prey S; Voisard J, Delarue A, et al.
      Abstract: This study uses data collected between April 2010 and April 2013 to assess the safety of propranolol for severe infantile hemangioma in children given this therapy under the French Health Products Agency compassionate use program.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Physical Activity vs Health Education in Sedentary Older Adults
    • Authors: Poulin MJ; Eskes GA, Hill MD.
      Abstract: To the Editor Dr Sink and colleagues reported that a 24-month moderate-intensity physical activity program did not improve global or domain-specific cognitive function compared with a health education program in sedentary adults. We have concerns about their working definition of moderate-intensity physical activity, the implementation and monitoring of the intervention, and the intensity of the physical activity intervention.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Nicotine Patch, Varenicline, or Combination Therapy for Smoking Cessation
    • Authors: Baker TB; Piper ME, Stein JH, et al.
      Abstract: This randomized trial compares the efficacy of varenicline, nicotine patch, and combination nicotine replacement therapy (patch plus lozenges) on smoking abstinence at 26 weeks among adults interested in quitting smoking.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Notice of Retraction
    • Authors: Eastell R; Hamilton CJ, Cummings SR.
      Abstract: To the Editor We wish to retract the article “Effect of Nitroglycerin Ointment on Bone Density and Strength in Postmenopausal Women: A Randomized Trial,” published in the February 23, 2011, issue of JAMA.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Addition of Missing Covariate
    • Abstract: In the Research Letter entitled “Association of the New York State Marriage Equality Act With Changes in Health Insurance Coverage” published in the August 18, 2015, issue of JAMA, the covariate “education” was left out of the Methods section and in the Table (footnote d). This article was corrected online.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Error in the Text
    • Abstract: In the Editorial entitled “Individual Benefit vs Societal Effect of Antibiotic Prescribing for Preschool Children With Recurrent Wheeze” published in the November 17, 2015, issue of JAMA, there was an error in the text. The APRIL study was incorrectly attributed to the CARE Network. This study was done by the National Heart, Lung, and Blood Institute’s AsthmaNet. Some text was also removed to aid clarity. This article was corrected online.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • JAMA Welcomes the US Preventive Services Task Force
    • Authors: Bauchner H; Fontanarosa PB, Golub RM.
      Abstract: The US Preventive Services Task Force (USPSTF) was created in 1984 by congressional authorization and “is an independent group of national experts in prevention and evidence-based medicine.” The intent of the USPSTF is “to improve the health of all Americans by making evidence-based recommendations about clinical preventive services such as: screenings, counseling services, and preventive medications.”
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Recommendations for Screening for Depression in Adults
    • Authors: Thase ME.
      Abstract: Although major depressive disorder (MDD) is one of the world’s great public health problems, the morbidity and increased mortality associated with this common illness can be attenuated by the large number of effective treatments that are now widely available. It is therefore important to ensure that efficient methods for population screening are in place and directly linked to health care systems so depressed patients receive appropriate treatment. This is particularly important because effective treatments of depression not only reduce symptoms associated with the disease and reduce the risk of suicide, but also can improve functioning and offset the negative effects that depressive symptoms can have on physical well-being. In the United States, like many other economically developed nations, primary care practices represent the best place for implementation of these methods, because it is the only venue where both screening and, if clinically indicated, treatment can be provided. With this ideal in mind, in 2002 and 2009 the US Preventive Services Task Force (USPSTF) published systematic reviews and recommendations for such screening for adults. In this issue of JAMA, Siu and colleagues provide the second update on this important topic.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Prenatal Vitamin D and Asthma Prevention
    • Authors: von Mutius E; Martinez FD.
      Abstract: In most large cities in the Northern hemisphere in the late 19th and early 20th centuries, rickets was an enormous public health problem, mainly because exposure to sunlight was limited, particularly for children. German physicians noticed that daily administration of a tablespoon of cod liver oil could reverse rickets, a finding that led to the discovery of vitamin D, its structure, and function. In the United States, most of the milk supply is now voluntarily fortified with vitamin D, whereas fortification of infant formula with vitamin D is mandatory. In many European countries, food fortification with vitamin D is not required by law, but vitamin D administration to infants and pregnant women is recommended. This public health intervention has been highly successful and has made rickets a rare disease.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Effect of Prenatal Vitamin D on Asthma in Offspring
    • Authors: Litonjua AA; Carey VJ, Laranjo N, et al.
      Abstract: This randomized clinical trial assesses whether high-dose vitamin D supplementation during the third trimester of women at high risk of having children with asthma reduces asthma or recurrent wheeze in their offspring.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Vitamin D 3 Supplementation During Pregnancy and Childhood Wheezing
    • Abstract: This randomized clinical trial compares the effects of vitamin D3 supplementation vs placebo during women’s third trimester of pregnancy on age at onset of persistent wheeze in the children in the first 3 years of life.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • JAMA
    • PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Screening for Depression
    • Authors: Jin J.
      Abstract: Depression is a type of mental illness that often goes unrecognized and untreated.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Epinephrine Administration and Pediatric In-Hospital Cardiac Arrest
    • Authors: Andersen LW; Berg KM, Donnino MW.
      Abstract: In Reply We do not have data on whether the first epinephrine bolus was administered by an intravenous or intraosseous injection. The variable we used for assessment of epinephrine administration included both intravenous and intraosseous administration but did not distinguish between the two.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Marriage Equality Act and Changes to Health Insurance Coverage
    • Authors: Long SK.
      Abstract: To the Editor Using data from the American Community Survey (ACS), Dr Gonzales analyzed the association between implementation of the Marriage Equality Act for same-sex couples in New York and their health insurance coverage. There are a few problems with the analysis.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Marriage Equality Act and Changes to Health Insurance Coverage
    • Authors: Gonzales G.
      Abstract: In Reply Dr Long is concerned about the measurement of same-sex couples in the ACS. Sexual orientation is not directly ascertained in the ACS. Same-sex couples are identified when the primary respondent identifies a cohabiting person in the household of the same sex as a husband, wife or unmarried partner, missing single LGB adults, same-sex couples not cohabiting together, and same-sex couples choosing not to disclose their relationship, which may bias the results. The findings should not be generalized to all LGB adults or same-sex couples.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Physical Activity vs Health Education in Sedentary Older Adults
    • Authors: Katula JA; Church T, Sink KM.
      Abstract: In Reply The purpose of the Lifestyle Interventions and Independence for Elders (LIFE) study was to test whether a long-term structured physical activity program reduced the risk of major mobility disability in individuals with compromised lower extremity functioning. Our recent article reported prespecified secondary cognitive outcomes.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Epinephrine Administration and Pediatric In-Hospital Cardiac Arrest
    • Authors: Poulton A; Chen F, Nanan R.
      Abstract: To the Editor The study by Dr Andersen and colleagues found an association between delayed administration of epinephrine and poorer survival rates after in-hospital pediatric cardiac arrest.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • I Feel Witty, Oh So Witty
    • Authors: Misch DA.
      Abstract: Improvisational comedy—“improv”—is a form of theater, typically performed by two or more actors, in which the story, including setting, plot, characters, and dialogue, are made up in the moment, often following a suggestion from the audience. Improv is, by definition, extemporaneous or off-the-cuff. In contrast, standup comedy consists of scripted, often carefully rehearsed performances by an individual actor.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Ushering Hypertension Into a New Era of Precision Medicine
    • Authors: Kotchen TA; Cowley AW, Jr, Liang M.
      Abstract: This Viewpoint discusses the potential influence of precision medicine that incorporates epigenetic analysis in effectively treating hypertension.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Highlights for January 26, 2016
    • PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • A Medicolegal Study of Blood Stains
    • Abstract: A question, not only of great theoretical but also of important medicolegal and practical interest, is the determination of the origin of blood stains on various articles. Chemical, biologic and immunologic research have been called on to aid in this study. Sutherland has recently reported the results of the examination of 6,566 articles suspected of being blood-stained in relation to 2,643 medicolegal cases. The question at issue in 1,650 of these cases was murder; in 284, assault; in 189, rape, and in other cases the questions involved practically every aspect of human life. The articles examined included the various body discharges—saliva, urine, feces, etc.—and virtually every form of animate and inanimate material. The determinations showed that various stains were due to the blood of such animals as the sheep, goat, ox, buffalo, dog, horse and pig, and various combinations.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Remembrance
    • Authors: Iacopetti CL.
      Abstract: Along the mountains of Tibet,square flags hang, printed with prayersand mantras that slowly fade. Their essence, it is said,dissolves into the windand uplifts all beings the wind touches.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Nkisi Nkondi (Nail Figure)
    • Authors: Cole TB.
      Abstract: The Kongo people of southwestern Africa are renowned for their raffia textiles, metal sculptures, funerary steles, and ritual icons. In the late 19th or early 20th century, a Kongo craftsman carved the wooden figure pictured here for the purpose of conjuring an nkisi, a type of familiar spirit that could be called upon to witness and enforce transactions in the community. It was probably exported from the Kongo region as a curiosity by a trader from Europe or North America in this era of disruptive cultural exchange (JAMA cover, September 12, 2012). Nkisi figures were fashioned from simple wooden statuettes purchased in the market for a few yards of cloth. At this stage a carving would have expressive facial features and a hollowed-out chamber in the belly or back of the head but otherwise would be unadorned. An nganga, or diviner, would then personalize the statuette and invest it with mystical powers by applying face paint, a headdress, clothing, a mirror, or other enhancements. Some nkisi figures, called nkisi nkondi, had aggressive stances to intimidate enemies, deflect malevolent spells, and warn bargainers to abide by their agreements. The raised arm of the figure in this image, which originally held a weapon, identifies it as an nkisi nkondi.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Rethinking Syringe Exchange
    • Abstract: Increased HIV and hepatitis C virus (HCV) infections in rural and suburban areas with injected opioid and heroin epidemics may push health officials to rethink syringe exchange programs, a recent study suggests.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • High-Risk College Sports
    • Abstract: More than 200 000 college athletes are injured in competition or practice each year, with men’s football and wrestling posing the highest risks, according to data that schools report to the National Collegiate Athletic Association (NCAA).
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • NIH Funds Cooperative Robot Research Projects
    • Authors: Jacob JA.
      Abstract: The National Institutes of Health (NIH) is giving a boost to the development of robots that help humans. The NIH has awarded grants to 3 researchers who are developing different types of assistive robots, known as cooperative robots, or co-robots ( The NIH grants, totaling $2.2 million subject to fund availability over the next 5 years, are part of the National Robotics Initiative, a federal interagency program to promote the development of co-robots (
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Public Health Campaign Focuses on Teen Sexual Health
    • Authors: Jacob JA.
      Abstract: About 1 of 4 sexually active teenage girls are infected with a sexually transmitted infection (STI) such as chlamydia or human papillomavirus (HPV), and moreover teenagers and young adults of both sexes aged 15 to 24 years accounted for two-thirds of reported chlamydial infections in 2014 (
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • CMS Reports Uptick in Health Care Spending
    • Authors: Jacob JA.
      Abstract: Health care spending in the United States increased by 5.3% in 2014 and reached an estimated $3 billion, accounting for 17.5% of the economy, according to a Centers for Medicare & Medicaid Services (CMS) study (Martin AB et al. Health Aff. doi:10.1377/hlthaff.2015.1194 [published online December 2, 2015]). While this increase in spending was greater than the average annual increase of 3.7% for the preceding 5 years, it was still less than the 6.9% average annual increases in health care spending that occurred between 2000 and 2009.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Progesterone Therapy of No Benefit for Recurrent Miscarriage
    • Authors: Slomski A.
      Abstract: A recent study found taking progesterone in the first trimester of pregnancy did not result in a greater rate of live births for women with a history of unexplained recurrent miscarriages (Coomarasamy A et al. N Engl J Med. 2015;373[22]:2141-2148). Approximately 1% of couples experience the loss of 3 or more pregnancies, and for more than half of couples, the cause of recurrent miscarriage is unknown.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Coaching Does Not Prevent Low-Value Diagnostic Testing
    • Authors: Slomski A.
      Abstract: An intervention designed to hone residents’ skills in handling patient requests for low-value diagnostic tests had no effect on whether residents actually ordered the tests for patients, according to a recent study (Fenton JJ et al. JAMA Intern Med. doi:10.1001/jamainternmed.2015.6840 [published online December 7, 2015]).
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Light Therapy Improves Major Depression
    • Authors: Slomski A.
      Abstract: Bright light treatment either alone or combined with the antidepressant fluoxetine hydrochloride was an effective and well-tolerated treatment for adults with nonseasonal major depressive disorder (MDD), according to a recent clinical trial (Lam RW et al. JAMA Psychiatry. doi:10.1001/jamapsychiatry.2015.2235 [published online November 18, 2015]).
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Clinicians Embrace 3D Printers to Solve Clinical Challenges
    • Authors: Kuehn BM.
      Abstract: This Medical News and Perspectives article discusses advances in 3-D printing that are being used to solve unique clinical challenges.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • The Graying of US Physicians
    • Authors: Kupfer JM.
      Abstract: This Viewpoint discusses the clinical performance of aging physicians as a factor in the larger question of how best to evaluate physician competency.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
  • Implementation Science and Delivery System Reform
    • Authors: Fisher ES; Shortell SM, Savitz LA.
      Abstract: In this Viewpoint, Elliott Fisher and colleagues review the emerging field of implementation science as a framework for planning innovations in health care delivery.
      PubDate: Tue, 26 Jan 2016 00:00:00 GMT
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