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Journal Cover Translational Surgery
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2468-5585 - ISSN (Online) 2455-9598
   Published by Medknow Publishers Homepage  [355 journals]
  • A preliminary study on forced expiratory volume in 1 s/forced vital
           capacity to predict prognosis of patients with lung cancer

    • Authors: Yechi Li, Jingqi Tian
      Pages: 57 - 61
      Abstract: Yechi Li, Jingqi Tian
      Translational Surgery 2017 2(3):57-61
      Aim: The purpose of the study is to verify if there is statistic difference of lung function before surgery based on differences in clinical characteristics (sex, age, degree of differentiation, size of tumor, tumor node metastasis (TNM), methods of surgeries, pleural metastasis, and lymph gland metastasis). Another purpose is to test if forced expiratory volume in 1 s/forced vital capacity obstruction (FEV1/FVC) is a risk factor of the prognosis of lung cancer. Methods: This retrospective study used t-test or analysis of variance to explore whether dramatic difference of lung function (FVC, FEV1, maximal voluntary ventilation [MVV], and FEV1/FVC) existed based on differences in clinical characteristics. The study used the Kaplan–Meier method to verify if FEV1/FVC could be a risk factor to predict the prognosis of lung cancer patients after surgeries. Results: The statistical results indicated that statistical difference of FVC existed between different age groups. In patients of different ages and sexes, there was statistically different MVV. Results of FEV1/FVC showed that FEV1/FVC varied dramatically in patients of different pleural metastasis conditions or TNM. Analysis of prognosis proved that in patients with a different differentiation degree, size of tumor, metastasis conditions of lymph gland, and TNM stage, a statistically different prognosis was found. As for groups of normal and abnormal FEV1/FVC, no apparently different prognosis was observed. Analysis of lung cancer patients of stage I indicated that the 5-year survival was dramatically different between patients of normal and abnormal FEV1/FVC. Conclusion: In lung cancer patients of stage I, FEV1/FVC was one of the risk factors of prognosis.
      Citation: Translational Surgery 2017 2(3):57-61
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ts.ts_37_16
      Issue No: Vol. 2, No. 3 (2017)
  • The role of ischemia-modified albumin levels in the diagnosis of acute

    • Authors: Ersin Turan, Baris Sevinç, Hüseyin Kurku, Gürcan Simsek, Recep Demirgül, Ömer Karahan
      Pages: 62 - 65
      Abstract: Ersin Turan, Baris Sevinç, Hüseyin Kurku, Gürcan Simsek, Recep Demirgül, Ömer Karahan
      Translational Surgery 2017 2(3):62-65
      Aim: Although there are several auxiliary laboratory tests, diagnosis of acute appendicitis (AA) mainly depends on clinical findings. The aim of this study was to evaluate the role of ischemia-modified albumin (IMA) in the diagnosis of AA. Methods: IMA levels of histopathologically confirmed AA cases and healthy volunteers were evaluated. Results: Mean IMA levels were 9.6 ± 12.5 absorbance units (ABSU) in the AA group and 3.04 ± 0.47 ABSU in the control group. Moreover, IMA levels positively correlated with the diagnosis of AA (r = 0.309, P = 0.013). The preoperative mean IMA level was 9.6 ± 12.5 ABSU, while the postoperative mean IMA level was 6.9 ± 11.7 ABSU (P = 0.001). There was a significant decrease in IMA levels after appendectomy. Conclusion: This study shows elevated IMA levels in patients with AA and a significant decrease of IMA levels after appendectomy. Oxidative stress plays a role in the pathogenesis of AA, and IMA levels can be used as an accessory parameter in diagnosis.
      Citation: Translational Surgery 2017 2(3):62-65
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ts.ts_13_17
      Issue No: Vol. 2, No. 3 (2017)
  • Central venous catheterization: An updated review of historical aspects,
           indications, techniques, and complications

    • Authors: Rafael Cardoso Pires, Noslen Rodrigues, Jonathan Machado, Ricardo Pedrini Cruz
      Pages: 66 - 70
      Abstract: Rafael Cardoso Pires, Noslen Rodrigues, Jonathan Machado, Ricardo Pedrini Cruz
      Translational Surgery 2017 2(3):66-70
      Central venous catheterization has become an indispensable procedure in various situations in the intensive care unit, emergency room and operation room. There are many applications such as invasive hemodynamic monitoring, parenteral nutrition support, dialysis, chemotherapy, fluid resuscitation and drug administration, though there are some complications associated with catheter placement. There are some articles that discuss the security and advantages of the anatomic landmark technique and ultrasound (US) guidance technique. In this non-systematic review article we searched the current data in Pubmed library.
      Citation: Translational Surgery 2017 2(3):66-70
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ts.ts_10_17
      Issue No: Vol. 2, No. 3 (2017)
  • Malignant and benign renal perivascular epithelioid cell tumors: A
           comparison and review of the literature

    • Authors: Pengliang Chen, Wenjie Lai, Zerong Chen, Shaobin Zheng
      Pages: 71 - 73
      Abstract: Pengliang Chen, Wenjie Lai, Zerong Chen, Shaobin Zheng
      Translational Surgery 2017 2(3):71-73
      While angiomyolipoma (AML) is a fairly common urological tumor, malignant AMLs rarely appear in clinical practice. As such, currently there exists little knowledge of malignant AMLs. This article discusses the differences between benign and malignant AMLs. Besides, we report two cases of AML with opposite nature in Nan Fang Hospital from 2010 to 2016 and discuss the key features based on clinical manifestation, pathogenesis, radiology, and pathology. Case 1 was a 44-year-old, asymptomatic female presenting with a mass measuring 4 cm in diameter in the inferior pole of the left kidney. Case 2 was a 23-year-old female presenting with abdominal pain for 1 month, a mass measuring 5.5 cm in diameter in the superior pole of the right kidney, regional infiltration, and enlarged retroperitoneal lymph nodes. Based on Folpe's grading scheme, the Case 1 tumor was benign due to the absence of criteria mentioned in the grade and the Case 2 tumor was malignant due to a tumor size >5 cm, infiltrative growth pattern, necrosis, high nuclear grade, and subsequent aggressive clinical behavior. Each patient underwent surgical resection: Case 1 demonstrated no evidence of recurrence at the 9-month follow-up; however, Case 2 died 3 years postoperation due to tumor recurrence. These results demonstrate that malignant AML has aggressive biological activities and almost always associates with unfavorable prognoses. Therefore, a strict follow-up should be given to “uncertain malignant potential” patients, and surgical resection should be performed.
      Citation: Translational Surgery 2017 2(3):71-73
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ts.ts_14_17
      Issue No: Vol. 2, No. 3 (2017)
  • Bilateral sarcomatoid renal cell carcinoma: An uncommon case in young
           female patient

    • Authors: Yuan Gao, Weibing Shuang, Xunan Tong, Yuhang Zhang
      Pages: 74 - 77
      Abstract: Yuan Gao, Weibing Shuang, Xunan Tong, Yuhang Zhang
      Translational Surgery 2017 2(3):74-77
      Sarcomatoid renal cell carcinoma (SRCC), an advanced and uncommon form of renal cell carcinoma (RCC), is more likely to manifest as a unilateral condition, especially in the right kidney, in older people. Here, we report a rare case of bilateral SRCC in a young female, aged 30 years - the youngest reported case of SRCC to the best of our knowledge. The patient complained of osphyalgia and intermittent fever which recurred after symptomatic treatment. Detailed examination, including histopathological analysis of biopsies, confirmed bilateral SRCC (RCC IV) with distant metastases. The patient denied receiving any form of the treatment, including surgery, radiotherapy, and chemotherapy and died approximately 6 months after the initial symptoms.
      Citation: Translational Surgery 2017 2(3):74-77
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ts.ts_6_17
      Issue No: Vol. 2, No. 3 (2017)
  • Traumatic diaphragmatic hernia in a pregnant woman

    • Authors: Oscar Arturo Nava Carmona, Luis Angel Medina Andrade, Silva Gonzalez Misael, Javier Carrillo Dartigues
      Pages: 78 - 80
      Abstract: Oscar Arturo Nava Carmona, Luis Angel Medina Andrade, Silva Gonzalez Misael, Javier Carrillo Dartigues
      Translational Surgery 2017 2(3):78-80
      Traumatic diaphragmatic hernia is always a challenge for diagnosis. The present case was a penetrating thoracoabdominal trauma in a pregnant woman that was not initially suspected but detected when adequate treatment was performed, and good results were obtained. Due to the high rate of associated complications, we should consider this diagnosis initially.
      Citation: Translational Surgery 2017 2(3):78-80
      PubDate: Fri,15 Sep 2017
      DOI: 10.4103/ts.ts_8_17
      Issue No: Vol. 2, No. 3 (2017)
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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Fax: +00 44 (0)131 4513327
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