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Journal Cover Journal of Food and Pharmaceutical Sciences
  [1 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Print) 2089-7200 - ISSN (Online) 2339-0948
   Published by Gadjah Mada University Homepage  [4 journals]
  • Montelukast: Much more than an antiasthma drug

    • Authors: Ghada M Suddek
      Abstract: Montelukast, a selective LTD4 receptor antagonist, is used mainly to reduce eosinophilic inflammation in asthmatic patients. The primary objective of this mini-review is to describe novel additional targets for montelukast besides the lung. Literature published between 2002 and 2012 was reviewed for significant antioxidant and antiinflammatory properties of montelukast in various experimental models of inflammation rather than that in the airways of asthmatics.  Evidence suggests the potential use of montelukast in many inflammatory diseases rather than asthma therapy. 
      PubDate: 2015-10-21
      Issue No: Vol. 3, No. 2 (2015)
  • Physico-chemical Amino acid composition, fatty acid profile, functional
           and antioxidant properties of Spinacia oleracea L. leaf

    • Authors: Prabhakara Rao Pamidighantam, Narsing Rao Galla, Narsing Rao Galla, Sulochanamma Guruguntla, Sulochanamma Guruguntla, Satyanarayana Akula, Satyanarayana Akula
      Abstract: Spinach (Spinacia oleracea L.) leaf powder (SLP) was prepared and its physicochemical (proximate composition, colour, mineral content, EMC-RH, protein solubility, amino acid content and fatty acid profile), functional (water absorption, fat absorption, emulsification and foam capacities) and antioxidant (DPPH, ABTS and Iron reducing power) properties were studied. SLP possessed a protein content of 31.72%, calcium (1335 mg/100g), iron (29 mg/100g) and phosphorous (278 mg/100g). Moisture sorption isotherms of SLP indicated its non-hygroscopic nature. Solubility of SLP protein in distilled water was 39.66%, which got enhanced to 72.83% in 0.1M NaCl at pH 12. The spinach leaf lipid was found to be rich in ω-3 fatty acids (67.4%). Leucine (11.87%), phenylalanine (5.9%) and valine (9.24%) were the major essential amino acids observed in SLP. Functional properties of SLP exhibited good water absorption, fat absorption and foam capacities. Antioxidant activity of SLP determined by the 2,2-azino-bis (3-ethyl benzothiazoline 6- sulphonic acid (ABTS) assay was found higher, when compared to the activities determined by diphenyl picrylhydrazyl (DPPH) and ferric reducing power assays. Protein solubility, amino acid content, fatty acid profile, functional properties and antioxidant characteristics encouraging for food and pharmaceutical applications.
      PubDate: 2015-05-21
      Issue No: Vol. 3, No. 2 (2015)
  • “Effect of various drying methods on quality and flavor
           characteristics of mint leaves (Mentha spicata L.)”

    • Authors: Sathiyamala Kripanand, Sulochanamma Guruguntla, srinivasulu korra
      Abstract: Mint leaves were dehydrated by hot air, shade as well as microwave drying and the respective drying time found, to lower the moisture content from (88%) to around (5%). The qualities of the dried products were assessed by determining the moisture, chlorophyll, carotenoid, polyphenols, color and volatile oil. In microwave drying, despite the less drying time, there were appreciable losses of volatile oil, chlorophyll and other components when compared to the fresh mint leaves. Results showed that Hot Air Drying (HAD) at 45°C followed by Micro Wave Drying (MWD) at 900 Watts possessed better quality parameters in the dried products suggesting that Hot Air Drying (HAD) was most suitable although it took more time compared to Micro Wave Drying (MWD). 
      PubDate: 2015-05-21
      Issue No: Vol. 3, No. 2 (2015)
  • Nutritional Composition of Momordica dioica fruits: As a wild vegetable

    • Authors: Jyotsna Salvi
      Abstract: Samples of Momordica dioica Roxb. ex Willd fruits were collected from Jhadol Tehsil of southern Rajasthan. The fruits were washed, ground into powder and analyzed for the proximate, vitamins, mineral and Fatty acid compositions. The values (% DW) of moisture, ash, crude protein, crude fiber, crude fat and carbohydrate available were 87, 14, 52.06, 15.36, 4 and 14.58, respectively. Levels (g/100g DW) of vitamins A, B1, B2, B6, H and K were 2.5, 1.8, 3.5, 4.3, 6.5 and 15 respectively. The values (mg/100g DW) of minerals potassium, sodium, calcium, zinc, Copper and magnesium were 370, 58, 26000, 8.5, 1.7 and 14000 respectively. Comparing the mineral and vitamin composition with recommended dietary allowances (RDA), the result indicated that Momordica dioica fruits could be good supplement for vitamin B1, B2, B6, B9, Ca and Mg. The values (% DW) of fatty acids i.e. Oleic acid, Palmitic acid, Linoleic acid, Myristic acid and Stearic acid of fruits were 56.253, 12.157, 22.511, 3.589 and 3.547 respectively.  The results indicated that Momordica dioica fruits could be a good supplement for some nutrients, minerals and fatty acids such as fiber, protein, carbohydrates, calcium, magnesium, Oleic acid, and Linoleic acid. The fruit could be promoted as a mineral and vitamin supplement for cereal-based diets in poor rural communities. 
      PubDate: 2015-05-01
      Issue No: Vol. 3, No. 2 (2015)
  • Development and validation of atomic absorption spectrometry for the
           determination of zink and mercury analyzer for determination of Mercury in
           cream cosmetics

    • Authors: Abdul Rohman, Erni Wijayanti
      Abstract: An atomic absorption spectrometry for the quantification of zink (Zn) and mercury analyzer  for the quantification of mercury (Hg) levels in cream cosmetic were developed and validated. The method was validated for linearity and range, precision, accuracy, limit of detection (LOD) and limit of quantification (LOQ). The standard curves were linear over the concentration of 0.1-1.2 µg/mL (Zn) and 0.05-2.0 µg/L (Hg) with coefficient of correlation (r) > 0.99. The detection limits obtained were 2.8614 µg/g sample (Zn) and 0.4749 ng/g sample. The quantification limit  obtained were 9.5281 µg/g sample (Zn) and 1.5827 ng/g sample. The relative standar deviation (RSD) values found to be 8.67 % for its intraday precision and 9.89 % for its interday precision (Zn) and 12.69 % for its intraday precision and 7.17 % for its interday precision (Hg). These RSD values are lower than those required by RSD Horwitz unction. The mean recovery percentage was 94.28 % (for Zn) and 78.65% (for Hg). These developed methods were succesfully used for determination of Zn and Hg in cream cosmetics products. Key words: mercury, zink, atomic absorption spectroscopy, mercury analyzer, cream cosmetic
      Issue No: Vol. 3, No. 2
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