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Journal of Dental, Oral and Craniofacial Epidemiology
  This is an Open Access Journal Open Access journal
     ISSN (Print) 2325-095X
     Published by SCASI Homepage  [2 journals]
  • Editorial

    • Authors: Elisabeth Santigli, Andrea Berghold
      Abstract: Editorial for the special issue on the occasion of the 5th International meeting on Methodological Issues in Oral Health Research held in Graz, Austria, in April 2012.
      PubDate: 2014-03-21
      Issue No: Vol. 1 (2014)
  • Use of the Oral Health Impact Profile (OHIP) in Clinical Oral Implant

    • Authors: Bernhard Pommer
      Abstract: The Oral Health Impact Profile (OHIP) is the most comprehensive and widely used instrument to measure oral health-related quality of life (OHQoL) currently available. Originally it consists of 49 items organized into 7 subscales (functional limitation, physical discomfort, psychological discomfort, physical disability, psychological disability, social disability and handicap) and responses are based on a Likert scale. In reviewing the current literature, the use of OHIP in the field of clinical oral implants research was evaluated. Of 39 studies identified, 15 used the short version OHIP-14 (38%), 7 used the OHIP-20 (18%), 13 used the full version OHIP-49 (33%) and 4 used the version for edentulous patients OHIP-EDENT (10%), while modified OHIP versions were used in another 2 studies. Further differences were seen regarding outcome definitions used (categorized vs. added evaluation). The majority of investigations (72%) used the OHIP to assess OHQoL in edentulous patients, while only few studies looked at partially edentulous patients (5%) or patients with tooth agenesis (5%). However, investigation often lack within-patient comparison of pre- vs. post-treatment conditions as well as inclusion of untreated controls. Although reference values have been suggested, reliable conclusions may only be drawn from comparative effectiveness research. Future studies may use the OHIP more frequently and accurately to gain further knowledge on the impact of oral implant treatment on OHQoL.
      PubDate: 2014-03-21
      Issue No: Vol. 1 (2014)
  • Factors Associated with Dental Fear in 12-35 Months Children Living in
           Krasnooktyabrski District of Volgograd – a pilot study. Revised
           Submission for DentalBiostat Special Issue of JDOCE

    • Authors: Elena E. Maslak, Darya S. Vlasova, Marina L. Yanovskaya, Svetlana V. Stavskaya, Natalia V. Kuyumdzhidi, Tatyana N. Kamennova
      Abstract: Background: Dental fear (DF) is the main barrier to receive dental care. Knowledge about factors contributing to DF development in young age can help improve dental service. Aim: To reveal factors associated with DF in children aged 12-35 months.  Methods: Cross-sectional investigation was conducted in 242 children aged 12-35 months.  The study was approved by Volgograd Regional Ethics Committee. Mothers’ informed consents were obtained. The children visited a dental office for the first time. The data about some family-mother-child factors was collected through mothers’ questioning. The children’s behavior was assessed with Frankl’s Behavior Rating Scale. The “negative” or “definitely negative” child’s behavior during the first dental appointment was considered a sign of DF development. Program STATISTICA-6 was used for statistical bevariate analysis. Number (%), 95% confidence interval (CI), chi-square (X2) and relative risk (RR) of dental fear development were calculated (p-value ≤0.05). Results: DF signs were revealed in 87 (35.9%) out of 242 children. Factors of children’s socialization (kindergarten attendance; communication with adults and peers; mother’s own DF; motivating and training for dental visits; contacting with medical personnel in a pediatric office; family relationships; more than one child families; family members involved in upbringing a child) were significantly associated with the change of relative risk of DF development in young children at the first dental appointment. Conclusions: The signs of DF were revealed in every third child of age under 3 years at the first dental appointment. Socializing factors are significantly associated with DF development in young children. 
      PubDate: 2013-10-13
      Issue No: Vol. 1 (2013)
  • Improving patient care using the Johnson-Neyman analysis of heterogeneity
           of treatment effects according to individuals’ baseline

    • Authors: Ann A Lazar, Stuart A Gansky, Donald D Halstead, Anthony Slajs, Jane A Weintraub
      Abstract: Because each patient’s baseline characteristics differ (e.g., age, sex, socioeconomic status, ethnicity/race, biomarkers), treatments do not work the same for every patient—some can even cause detrimental effects. To improve patient care, it is critical to identify such heterogeneity of treatment effects.  But the standard analytic approach dichotomizes baseline characteristics (low vs. high), which often leads to a loss of critical patient-care information and power to detect heterogeneity, as the results may depend strongly on the cut-points chosen.  A more powerful analytic approach is to analyze baseline characteristics (i.e., covariates) measured on a continuous scale that retains all of the information available for the covariate. In this article, we show how the Johnson-Neyman (J-N) method can be used to identify the prognostic and predictive value of baseline covariates measured on a continuous scale─findings that often cannot be determined using the traditional dichotomized approach.  As an example, we used the J-N method to explore treatment effects for varying levels of the biomarker salivary mutans streptococci (MS) in a randomized clinical prevention trial comparing fluoride varnish with no fluoride varnish for 376 initially caries-free high-risk children, all of whom received oral health counseling.  The J-N analysis showed that children with higher baseline MS values who were randomized to receive fluoride varnish had the poorest dental caries prognosis and may have benefitted most from the preventive agent.  Such methods are likely to be an important tool in the field of personalized oral health care.
      PubDate: 2013-10-13
      Issue No: Vol. 1 (2013)
  • Next-generation sequencing in microbiome analysis: factors affecting
           reproducibility of repeated biofilm sampling of the gingival sulcus of

    • Authors: Slave Trajanoski, Barbara Klug, Ingeborg Klymiuk, Michael Bozic, Martin Grube, Gernot Wimmer, Elisabeth Santigli
      Abstract: Background: Microbiome analysis underwent a methodological revolution during the last decade. New culture-independent methods were developed that render complete microbiome datasets, posing a challenge to data analysis. The purpose of the present study was to demonstrate pyrosequencing data processing for the characterization of the subgingival microbiome in healthy children and to examine the reproducibility of paper point sampling. Material and Methods: 20 subgingival plaque samples were taken in parallel and consecutive performances from five children. Microbial community profiles of the biofilm were determined using 454 pyrosequencing of the V5 and V6 hypervariable regions of 16S rRNA. In a multi-step process, data generated from two sequencing runs was analyzed using the Quantitative Insights Into Microbial Ecology (QIIME) pipeline for comparison of microbial communities. Principal Coordinate Analysis (PCoA) was applied in order to visualize sample similarities and differences. Results: From a total of 223,648 reads from both sequencing runs after clustering step at 97% similarity, 2,617 OTUs were classified in 11 phyla with the majority accounted for: Bacteroidetes (27.24%), Actinobacteria (14.21%), Firmicutes (17.92%), Proteobacteria (10.85%), Spirochaetes (4.09%) and Fusobacteria (3.59%). Rarefaction curves displayed sufficient species present for the establishment of proper microbial profiles. Sample comparison by taxonomic summary and Principal Coordinate Analysis validated reproducibility of the results. Conclusion: Paper point sampling is a reliable technique for pyrosequencing-based characterization of the subgingival microbiome. Results show high intra-subject similarities compared to inter-subject variability. Differences in raw sequence data do not influence microbiome profiles.
      PubDate: 2013-10-13
      Issue No: Vol. 1 (2013)
  • Development and implementation of an oral health data registration and
           evaluation system for the Belgian population

    • Authors: Dominique Declerck, Peter Bottenberg, Joana Carvalho, Catherine Declerck, Eddy De Vos, Astrid Vanden Abbeele, Jean-Pierre Van Nieuwenhuysen, Jacques Vanobbergen, Kris Bogaerts
      Abstract:  Background: Information regarding health condition, related behavior and utilization of health care services is essential for planning and organization of care delivery. Until recently, only limited information regarding oral health related issues was available in Belgium.
      Aim: This paper illustrates the development and implementation of an Oral Health Data Registration & Evaluation System (OHDRES) in Belgium, including discussion of challenges encountered.
      Methods: After development of a conceptual plan and pilot phase, the OHDRES was implemented nationwide in 2009-2010. The combined Health Interview (self-administered questionnaire) and Health Examination (standardized oral examination by trained dentist-interviewer at the participant’s home) data were supplemented with data on utilization of (oral) health care services. Sampling of Belgian residents (> 5 years) took place using a multi-stage, stratified cluster sampling procedure. Ethical approval was obtained and informed consent was sought from all participants.
      Results: A total of 2536 households were reached, yielding 3057 respondents (52%). Questionnaire and clinical data were obtained from 90% and 84% of participants. Dentist-interviewers reported difficulties with scoring of periodontal condition and enamel defects. Contacting selected households was the most difficult and time-consuming task for the dentist-interviewers, impacting on retention rate.
      Conclusion: The first round of the Belgian OHDRES was successfully implemented, after long and complex preparation. The impossibility of integration with the National Health Interview Survey 2009 was a considerable draw-back complicating data collection and limiting opportunities to further data linking and creation of added value.
      Acknowledgements: Project initiated and financed by Belgian National Institute for Health and Disability Insurance. 
      PubDate: 2013-10-13
      Issue No: Vol. 1 (2013)
  • 6th International Meeting on Methodological Issues in Oral Health Research
           in Adelaide, Australia

    • Authors: Gloria Mejia
      Issue No: Vol. 1
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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Fax: +00 44 (0)131 4513327
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