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Journal Cover European Review for Medical and Pharmacological Sciences
  [SJR: 0.569]   [H-I: 33]   [3 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1128-3602
   Published by Verduci Editore Homepage  [1 journal]
  • Assessment of celecoxib poly(lactic-co-glycolic) acid nanoformulation on
           drug pharmacodynamics and pharmacokinetics in rats
    • Authors: gianni
      Abstract: OBJECTIVE:  Celecoxib (CEL) is a nonsteroidal anti-inflammatory drug (NSAID) showing selective cycloxygenase-2 inhibition. While effective as a pain reducer, CEL exerts some negative influence on renal and gastrointestinal parameters. This study examined CEL pharmacodynamics and pharmacokinetics following drug reformulation as a poly(lactic-co-glycolic) acid nanoparticle (NP). MATERIALS AND METHODS: Rats were administered either vehicle (VEH) (methylcellulose […]L'articolo Assessment of celecoxib poly(lactic-co-glycolic) acid nanoformulation on drug pharmacodynamics and pharmacokinetics in rats sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 10:45:51 +000
       
  • SCH 79797, a selective PAR1 antagonist, protects against
           ischemia/reperfusion-induced arrhythmias in the rat hearts
    • Authors: gianni
      Abstract: OBJECTIVE: Thrombin is implicated in the genesis of arrhythmias and activation of thrombin receptors exacerbated ventricular arrhythmias following coronary artery ligation. The present study was designed to investigate the possible protective effect of the protease-activated receptor-1 antagonist, SCH79797 against ischemia and reperfusion arrhythmias in the rat heart. MATERIALS AND METHODS: Healthy male Wistar rats (250-350 […]L'articolo SCH 79797, a selective PAR1 antagonist, protects against ischemia/reperfusion-induced arrhythmias in the rat hearts sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 10:40:29 +000
       
  • The effect of low dosage of procaine on lung cancer cell proliferation
    • Authors: gianni
      Abstract: OBJECTIVE: Non-small cell lung cancer (NSCLC) is the most common type of human lung cancer leading cause of cancer death worldwide. However, first-line drugs such as gefitinib and erlotinib showed great drug resistance in the clinical. MATERIALS AND METHODS: The cell proliferation was evaluated by MTT assay; gene expression was detected by qPCR assay. The […]L'articolo The effect of low dosage of procaine on lung cancer cell proliferation sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 10:32:57 +000
       
  • Prostaglandin E2, trace elements and levels of oxidative processes in
           spontaneous miscarriages
    • Authors: gianni
      Abstract: OBJECTIVE: We investigated the significance of prostaglandin (PG)E2, trace elements level, pro-oxidative and antioxidative parameters changes in spontaneous miscarriages. PATIENTS AND METHODS: In the 125 first trimester pregnancies, 35 with complete spontaneous abortion (group S), 40 with missed abortion (M) and 50 healthy (H), PGE2 plasma concentrations were analysed by commercial ELISA kits, plasma trace […]L'articolo Prostaglandin E2, trace elements and levels of oxidative processes in spontaneous miscarriages sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 09:13:41 +000
       
  • Infective endocarditis – A word of caution on non-typical bacteria
    • Authors: gianni
      Abstract: A previously healthy 52-year-old man presented to our department with remitting and relapsing fever for more than 6 weeks. During complex staged work-up, we revealed that he suffered from an Abiotrophia defectiva endocarditis of the mitral valve with mitral regurgitation and vegetation requiring mitral valve replacement. He recovered well postoperatively and is currently being followed […]L'articolo Infective endocarditis – A word of caution on non-typical bacteria sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 09:10:46 +000
       
  • Analysis of factors influenced by the effectiveness of non-invasive
           ventilation in the treatment of acute exacerbation of chronic obstructive
           pulmonary disease with different severities
    • Authors: gianni
      Abstract: OBJECTIVE: To investigate the correlation of levels of procalcitonin (PCT) and blood lactic acid with the effectiveness of the non-invasive ventilation (NIV) in the treatment of acute exacerbation of chronic obstructive pulmonary disease (AECOPD) with different severities. PATIENTS AND METHODS: We used a case-control method to study patients who were admitted for AECOPD to the […]L'articolo Analysis of factors influenced by the effectiveness of non-invasive ventilation in the treatment of acute exacerbation of chronic obstructive pulmonary disease with different severities sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 09:07:18 +000
       
  • S100B in serum and saliva: a valid invasive or non-invasive biomarker in
           obstructive sleep apnea'
    • Authors: gianni
      Abstract: OBJECTIVE:  The aim of this prospective study was to determine whether serum or saliva S100B could be established as an invasive or non-invasive biomarker of cerebrovascular stress due to chronic intermittent hypoxia in obstructive sleep apnea (OSA). PATIENTS AND METHODS: S100B levels in serum and saliva were measured by an enzyme-linked immunosorbent assay (ELISA) in […]L'articolo S100B in serum and saliva: a valid invasive or non-invasive biomarker in obstructive sleep apnea' sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 09:03:47 +000
       
  • The correlation between children’s status asthmatics and
           interstitial lung disease
    • Authors: gianni
      Abstract: OBJECTIVE: Investigating the correlation between children’s status asthmatics and interstitial lung disease (ILD). PATIENTS AND METHODS: We continuously selected 20 cases of children’s status asthmatics combined with ILD (group A), 20 cases of pure status asthmatics (group B), 20 cases of pure ILD (group C) and 20 cases of healthy children (group D). We measured […]L'articolo The correlation between children’s status asthmatics and interstitial lung disease sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 08:59:10 +000
       
  • Continuous monitoring of intracranial pressure for prediction of
           postoperative complications of hypertensive intracerebral hemorrhage
    • Authors: gianni
      Abstract: OBJECTIVE: This study evaluates the value of continuous dynamic monitoring of intracranial pressure (ICP) in patients with hypertensive intracerebral hemorrhage to predict early postoperative complications. PATIENTS AND METHODS: Data from 80 patients treated in our hospital from February 2014 to February 2015 were analyzed. The patients all underwent decompressive craniectomies, and their ICP changes were […]L'articolo Continuous monitoring of intracranial pressure for prediction of postoperative complications of hypertensive intracerebral hemorrhage sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 08:19:39 +000
       
  • The role of diet on gut microbiota composition
    • Authors: gianni
      Abstract: Gut microbiota is characterized by an inter-individual variability due to genetic and environmental factors. Among the environmental ones, dietary habits play a key role in the modulation of gut microbiota composition. There are main differences between the intestinal microbiota of subjects fed with prevalent Western diet and that of subjects with a diet rich in […]L'articolo The role of diet on gut microbiota composition sembra essere il primo su European Review.
      PubDate: Thu, 24 Nov 2016 08:17:19 +000
       
 
 
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