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Journal Cover   American Journal of Medical and Biological Research
  [3 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Print) 2328-4080 - ISSN (Online) 2328-4099
   Published by Science and Education Publishing Homepage  [72 journals]
  • Cissus populnea (Guill & Perr): A Study of the Aqueous Extract as
           Potential Spermatogenic Enhancers in Male Wistar Rats

    • Authors: Anthony B. Ojekale; Oladipupo A. Lawal, Peter I. Jewo, Jamiu. A. Oguntola, Latifat O. Abdul
      Pages: 124 - 127
      Abstract: Background: There is a global observed decline in male fertility over the years consequent on various factors affecting spermatogenesis. Some Nigerian males across various geographic and socio-economic strata employ the use of herbals such as Cissus populnea extracts amongst others to manage this and also as herbal aphrodisiacs. This study assessed the spermatogenic effects of aqueous extract of Cissus populnea stem bark. Methodology: Cissus populnea stem bark was extracted with water, concentrated and lyophilized. Male wistar rats were orally administered with 150 mg/kg body weight of aqueous extract (Cissus populnea) over a 64 day period. Sperm of the experimental animals was collected, and the parameters (count, motility, morphology) analysed. Data were analysed with SPSS 19. Principal findings: The oral administration of C. populnea extract over a 64 day period to male wistar rats resulted in a four-fold increase in sperm count in the test rats (145±55) compared with the control group (44±17). Testicular histology shows better packed spermatozoa in group of rats treated with Cissus populnea. Conclusion/significance: The findings suggest that oral administration of Cissus populnea aqueous extract improves spermatogenesis in male wistar rats.
      PubDate: 2015-06-28
      Issue No: Vol. 3, No. 5 (2015)
  • Monitoring of Thoracic Aortic Aneurysm in Blood by Fluorescence

    • Pages: 128 - 132
      Abstract: Components of the blood plasma and serum represent a mixture of various endogenous substances with fluorescence properties. The aim of this work was a detection of pathological changes in blood of patients with thoracic aortic aneurysm by fluorescence spectroscopy and atomic force microscopy. The resulting autofluorescence of fluorophores in blood of patients with thoracic aortic aneurysm decreased in comparison with healthy subjects. The structure of the thoracic aorta was changed during the thoracic aortic aneurysm, what was manifested as the structural modifications in blood of patients observed by using atomic force microscopy. The fluorescence analysis and atomic force microscopy present new experimental ways in the study of the thoracic aortic aneurysm.
      PubDate: 2015-08-05
      Issue No: Vol. 3, No. 5 (2015)
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