for Journals by Title or ISSN
for Articles by Keywords
help
Followed Journals
Journal you Follow: 0
 
Sign Up to follow journals, search in your chosen journals and, optionally, receive Email Alerts when new issues of your Followed Journals are published.
Already have an account? Sign In to see the journals you follow.
Journal Cover American Journal of Infectious Diseases and Microbiology
  [17 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 2328-4056 - ISSN (Online) 2328-4064
   Published by Science and Education Publishing Homepage  [72 journals]
  • Diagnosis of Brucella Infection in Sheep and Goat and Evaluation of the
           associated Practices in Animal Contacts

    • Authors: Sultan Farag Nagati; Safaakhamis Hassan
      Pages: 95 - 101
      Abstract: Brucellosis is major zoonosis that affects health and economy in many parts of the world. Brucellosis remains an uncontrolled problem especially in several regions of high endemicity such as the Mediterranean, Middle East. Transmition of Brucellosis in humans is strongly related to contact with infected animals. Diagnosis of brucellosis is based on microbiological and serological laboratory test. Methodology: A cross-sectional study was conducted between January 2016 to June 2016 to estimate the seroprevalence of brucellosis in the small ruminants. A total of 315 blood samples collected from sheep, goats and human contacts with animals in the age from 15 to 58 yearswere tested by Rose Bengal test. Also, bacteriological examination was done for 171 available milk samples small ruminants (134 sheep and 37 goats), one sample of stomach and visceral content from aborted fetus of goat and five blood samples of human contact with a current history of fever. PCR was employed. Results: The prevalence in human was (16) 15.2% and in small ruminants was (40)19% and the risk of infection was associated with increasing age, assistance in labour, presence of infected animal with brucellosis and who giving their animal males for fertilization other flocks. Conclusion: There were 56 positive Rose Bengal test in sheep, goats and human. All recovered isolates of brucella were B. melitesisbiovar 3 and confirmed by PCR. It is probable that they share the sameorigin of infection. The general public, especially where brucellosis present has to be made aware of the danger to health.
      PubDate: 2016-10-13
      Issue No: Vol. 4, No. 5 (2016)
       
  • The Interleukin-8 -251 A Allele is Associated with Increased Risk of
           Different Gastroduodenal Diseases in H. pylori Infected Bangladeshi
           Patients

    • Authors: Ritu Saha; Md. Ashraful Islam, Abu Naser Ibne Sattar, Sharmeen Ahmed
      Pages: 102 - 106
      Abstract: Persistent Helicobacter pylori infection leads to chronic inflammation of the gastric mucosa which is mediated by various inflammatory cytokines. Host susceptibility along with bacterial virulence factors are also regarded as contributing factor of developing severe H. pylori induced gastroduodenal diseases like peptic ulcer diseases and gastric adenocarcinoma. Polymorphisms in genes that code cytokines influence cytokine secretion levels. Of the inflammatory cytokines, Interleukin-8 (IL-8) plays an important role in gastric mucosal inflammation induced by H. pylori infection. The IL8 gene has been described as having a polymorphism of an A/T base pair in the promoting region (−251) which is associated with an increased synthesis of interleukin by gastric epithelial cells. So the study was conducted to investigate the association of IL-8–251 A/T polymorphism with gastroduodenal diseases in H. pylori infected Bangladeshi patients. Methods: Endoscopic gastroduodenal biopsy sample of 113 dyspeptic patients were used (54 was infected with H. pylori and 59 was not infected with H. pylori). H. pylori infection was detected by Rapid urease test, PCR of ureC gene and histology. Gastroduodenal disease was diagnosed by histopathological examination. Il-8 gene polymorphism (at -251 position) was detected by Polymerase Chain Reaction restriction fragment length polymorphism. Result: A significant association was found between host IL-8 genotypes (T/T, T/A, A/A and A carrier) and the presence of H. pylori infection (p =0.001). The IL-8 A allele carriers infected with H. pylori had an increased risk of developing gastritis (p =0.003) and peptic ulcer diseases (p= .002). We did not find a correlation between IL-8 gene polymorphism and a higher risk of gastric carcinoma and or precancerous lesions. Conclusion: The H. pylori infected patients carrying A allele may increase risk of developing gastritis and peptic ulcer disease in Bangladeshi patients.
      PubDate: 2016-10-27
      Issue No: Vol. 4, No. 5 (2016)
       
 
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
 
Home (Search)
Subjects A-Z
Publishers A-Z
Customise
APIs
Your IP address: 54.205.140.252
 
About JournalTOCs
API
Help
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-2016