Journal Cover American Journal of Infectious Diseases and Microbiology
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  This is an Open Access Journal Open Access journal
     ISSN (Print) 2328-4056 - ISSN (Online) 2328-4064
     Published by Science and Education Publishing Homepage  [72 journals]
  • Toxic Effect of Babesiosis in Cattle and Chemotherapiotic Treatment in

    • Authors: Ahlam F. Hamoda; Mervat Radwan, Rabab Rashed, Aziza Amin
      Pages: 91 - 96
      Abstract: Babesia bigemina plays an important role in causing liver and kidney dysfunction in affected animals. The aim of this study evaluating the toxic effect of babesiosis on liver and kidney by measuring biochemical parameters and pathological tissue changes in infected animals with B. Bigemina and chose the best method of treatment. A total of 40 cattle age 1-3 years 30 were suffered from increase in temperatures, off food, Hemoglobin urea, red water from endemic area with babesia. Take sample from infected animals & examine it with microscopic examination found babesia bigemina and confirm by inoculation of heparinized blood from this animals in rats and found rats death at fifth day from infection and histopathological exam found babesia in piroplasma form in pathological tissue of rat’s liver & kidney. The infected animals were divided into three groups each group 10 animals untreated group use as control positive and treated groups divided into two groups first group treated with imidocarb only and the second group use imidocarb and lincomcyn as antibiotic drug and compare between two groups by measuring liver& kidney function improvement and compare two groups with negative and positive group which method of treatment more effective in treatment of babesia & decrease toxic effect of babesia.
      PubDate: 2014-10-24
      Issue No: Vol. 2, No. 5 (2014)
  • Isolation and Characterization of Microbial Contamination from Computer
           Accessories used in Different Department of Hazara University and
           Diagnostic Laboratories of District Mansehra, Pakistan

    • Authors: Zeba Gul Burki; Faiza Naseer, Sohail Ahmad
      Pages: 97 - 109
      Abstract: 150 samples were collected from computer accessories used in Hazara University and different diagnostic laboratories of Mansehra, examined for the total bacterial count and maximum growths were observed. Samples were analyzed for further identification of micro-organisms such as E.coli, Klebsiella, S taph. aureus and Staph. epidermidis . These organisms were detected in the percentage of 46.66 of E. coli, 20% of Klebsiella, 16.66% of S. aureus & 16.66% of S. Epidermidis and identified on selective media, i.e. EMB agar and Mannitol salt agar. Furthermore, biochemical tests, including IMVIC Test, Catalase Test and Coagulase Tests were performed to confirm the presence of micro-organisms and their susceptibility also checked against different standard antibiotics and their zone of inhibitions were measured and noticed. E.coli showed maximum resistance of 97.36% against Erythromycin, Klebsiella showed against Amoxil + Clavolunic acid about 83.83%, Staph aureus showed against Erythromycin about 64.64% and Staph. e pidermidis resistance was 90.9% against Erythromycin and Gentamycin. E.coli and Klebsiell a showed maximum sensitivity for Meropenem 67.22% and 72.72% respectively while S taph. aureus and Staph. epidermidis maximum sensitivity for Vancomycin about 82.82% and 72.72% respectively. These results indicate that the computer accessories might act as environmental vehicles for the transmission of potentially pathogenic bacteria in our surroundings and also indicate the need for increasing awareness among computer users on cleaning of such surfaces or disinfection and adequate hand-washing hygiene.
      PubDate: 2014-10-24
      Issue No: Vol. 2, No. 5 (2014)
  • Parainfluenza Virus Type-3 Outbreak in Level II Neonatal Care Unit: Role
           of Nursing Infants inside Closed Incubators in the Control of the Viral

    • Authors: Khalil Al Tawil; Saif Alsaif, Atef Alshafei, Vivian Manzano, Ali Hajeer, Hesham Tawakol
      Pages: 117 - 121
      Abstract: Parainfluenza type 3 virus (PIV-3) outbreaks in neonatal care units are rare. We aimed to report our experience of PIV-3 outbreak in level II neonatal care unit (NCU-II). A retrospective review of medical records of all infants managed in NCU-11 during the PIV-3 outbreak period. During the viral outbreak, 49 infants were cared for in NCU-II, and only 7 infants proved to be infected with PIV-3. The attack rate was 14%. The first 4 infected infants were transferred to standby isolation room outside NCU-II, and the unit was closed. All exposed and infected infants were cohorted, nursed inside closed incubators and other infection control measures were reinforced. Due to bed crises and 5 days after the closure of the unit and before the end of the viral outbreak; the standby isolation room was closed and NCU-II was reopened for new admissions and was divided into 3 zones for: infected, exposed, and newly admitted infants. Three more infants that were initially exposed to index case turned positive. There was no further transmission of the PIV-3 after opening the neonatal unit. Infants nursed in open crib at onset of PIV-3 outbreak were at high risk for infection (P value
      PubDate: 2014-11-04
      Issue No: Vol. 2, No. 5 (2014)
  • N-acetylcysteine Inhibits and Eradicates Candida albicans Biofilms

    • Authors: Rehab Mahmoud Abd El-Baky; Dalia Mohamed Mohamed Abo El Ela, Gamal Fadl Mamoud Gad
      Pages: 122 - 130
      Abstract: N-acetylcysteine (NAC) is used in the treatment of chronic bronchitis that attributed to its mucus dissolving properties. Its ability to reduce biofilm formed by different types of bacteria was proven previously in many studies. Therefore we examined its effect on C. albicans biofilms by testing its effect alone and in combination with ketoconazole using Tissue culture plate assay method (TCP). NAC effects on C. albicans morphology and the texture of biofilms were determined using Scanning electron microscope (SEM). It was found that the inhibitory effect of NAC was concentration dependent. NAC reduced C. albicans adherence by ≥32.8% while ketoconazole reduced adherence by ≥25% in comparison to control. Also, it showed higher disruptive effect (50-95%) than ketoconazole (22-80.7%) on mature biofilms. Using NAC and ketoconazole in combination, a significant inhibitory effect (P
      PubDate: 2014-11-04
      Issue No: Vol. 2, No. 5 (2014)
  • Cerebral Abscess Caused by Streptococcus spp in a Patient with Chronic
           Suppurative Otitis Media (CSOM)

    • Authors: K V Ramana; K Maheshwar Reddy, Padmawali Palange, B Mohan Rao, Sanjeev D Rao
      Pages: 131 - 137
      Abstract: Chronic suppurative otitis media (CSOM) is a clinical condition where a patient suffers from external and middle ear infection caused mostly by bacteria or by fungi resulting in ear discharge. Identification of the causative microorganism and initiation of appropriate antimicrobial chemotherapy is needed in patients suffering from CSOM. Infections of the ear if happen to be chronic in nature have the tendency to leak in to the adjacent areas of the central nervous system causing severe complications.
      PubDate: 2014-11-12
      Issue No: Vol. 2, No. 5 (2014)
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