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Journal Cover Anatolian Journal of Psychiatry
  [SJR: 0.183]   [H-I: 6]   [3 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Print) 1302-6631
   Published by ScopeMed Homepage  [99 journals]
  • Validity and Reliability of the Turkish version of DSM-5 Depression
           Severity Scale-Child Form

    • Abstract: 2016-06-19T23-16-30Z
      Source: Anatolian Journal of Psychiatry
      Şermin Yalın Sapmaz, Nefize Yalın, Handan Özek Erkuran, Siğnem Öztekin, Bengisu Uzel Tanrıverdi, Ertuğrul Köroğlu, Ömer Aydemir.
      Objective: This study aimed to assess the validity and reliability of the Turkish version of DSM-5 Depression Severity Scale-Child Form. Methods: The scale was prepared by carrying out the translation and back-translation of DSM-V Depression Severity Scale-Child Form. Study group consisted of 46 patients that have been treated in a child psychiatry unit and diagnosed with depressive disorder and 135 healthy volunteers that were attending middle or high school during the study period. For the assessment, Child Depression Inventory (CDI) was used along with DSM-5 Depression Severity Scale-Child Form. Results: Regarding reliability analyses, Cronbach’s alpha internal consistency coefficient was calculated as 0.911 while item-total score correlation coefficients were measured between 0.579 and 0.801. As for construct validity, a factor that could explain 59.2% of the variance was obtained and was consistent with the original structure of the scale. In the concurrent validity analysis, the scale showed a very high correlation with Child Depression Inventory with a correlation coefficient value measured as r=0.847. Conclusion: It was concluded that Turkish version of DSM-5 Depression Severity Scale-Child Form could be utilized as a valid and reliable tool both in clinical practice and for research purposes.

      PubDate: Sat, 18 Jun 2016 12:42:39 GMT
  • Hiccups secondary to selective serotonin reuptake inhibitory drugs: case

    • Abstract: 2016-06-19T23-16-30Z
      Source: Anatolian Journal of Psychiatry
      Emrah Songur, Rıdvan Üney.
      Hiccups are involuntary and intermittent contraction of the diaphragm and the intercostal muscles. Hiccup is usually a self-limited disorder, but it is needed to use physical interventions and pharmacological treatment for some intractable hiccups. In medical literature some cases, treated with drugs that effect on serotonergic system, are described for intractable hiccups. In this case report, we aim to present a hiccup case secondary to selective serotonin reuptake inhibitory drugs (paroxetine, fluoxetine and sertraline respectively) in a 28-year-old man with major depression with psychotic features.

      PubDate: Sat, 18 Jun 2016 12:32:32 GMT
  • Projections of certain social ties defined by Vamik Volkan on ancient
           Cappadocian coins

    • Abstract: 2016-06-19T23-16-30Z
      Source: Anatolian Journal of Psychiatry
      Selçuk Kırlı, Nuran Şen, Mustafa Şahin.
      Objective: This study aims to analyze the reflections of certain social ties defined by Volkan, which constitute a wider group identity when combined together and enable the group to maintain its existence, on ancient Cappadocian coins; and thereby to indicate how these concepts go beyond being concepts of the present day and apply to ancient times as well. Methods: For the purpose of this study, we screened the national and international collections of ancient Cappadocian coins, examining the symbols on these coins by taking into consideration the particulars of the historical development of the Kingdom as well as its relations with neighboring kingdoms. To that end, all significant historical events concerning the kingdom throughout the period starting before its foundation to its abolition as well as the coins issued within such period and the symbols thereon are presented in tabular form in comparison to the coins of the neighboring kingdoms of the same era. Results: Coins issued in the Kingdom of Cappadocia until 280 B.C. and the symbols thereon have evident characteristics of ancient Persian culture. Coins issued between 280-163 B.C. reflect characteristics of the Greek culture and Persian symbols together. Between 163-86 B.C. the coins acquired completely Hellenistic characteristics, which continued until 36 B.C. Another distinction is observed in symbols on the coins during the reign of King Archelaos. When compared with the neighboring kingdoms, it is seen that the symbols on Cappadocian coins have characteristics both similar to, and evidently distinct from those of the neighboring kingdoms.

      PubDate: Sat, 18 Jun 2016 12:24:30 GMT
  • Xanthine oxidase, adenosine deaminase and vitamin E levels in patients
           with schizophrenia

    • Abstract: 2016-06-08T23-15-29Z
      Source: Anatolian Journal of Psychiatry
      Hasan Kılıçgün, E. Erdal Erşan, Sevtap Bakır, Serpil Erşan, Derya Koç, Özlem Demirpençe, Kübra Doğan.
      Objective: Neuronal damage caused by free radicals is believed to be effective in pathogenesis of several psychiatric disorders. This belief is due to the toxic effects of free radicals that play a role in oxidative stress. Considering that the brain is one of the most sensitive organs to the oxidative damage, the importance of oxidative stress in psychiatric disorders will become more apparent. Additionally, high oxygen use in the brain, and its structure rich in lipid, which is one of the most sensitive molecules to the free radical damage, and its having the average antioxidant system yield support oxidative stress theory in the pathogenesis of psychiatric disorders. This study aimed to determine xanthine oxidase (XO), adenosine deaminase (ADA) and vitamins E levels in patients with schizophrenia and control groups, and to investigate the relationship between schizophrenia and the parameters by comparing the measured parameters with each other. Methods: Our study sample included 30 patients diagnosed with schizophrenia. The control group consisted of 30 healthy volunteers matched by sex with similar age and smoking habits. In the patient group and the control group, adenosine deaminase, xanthine oxidase, and vitamin E were measured manually using spectrophotometric methods. Results: Serum xanthine oxidase levels in the schizophrenic group were significantly higher than the control group levels. Serum vitamin E and adenosine deaminase levels in the schizophrenia group were significantly lower than the levels of the control group. Discussion and Conclusion: The fact that mechanism of schizophrenia pathogenesis which has a wide variety of clinical symptoms and a disease process is yet to be elucidated reveals the importance of this kind of studies. In this study, low levels of antioxidant vitamin E and adenosine deaminase, and high levels of xanthine oxidase suggest that oxidative stress-mediated neuronal damage may play a role in the pathogenesis of schizophrenia. Therefore, we believe that further research with larger sample groups should be conducted.

      PubDate: Wed, 08 Jun 2016 00:03:17 GMT
  • The prevalence and risk factors of psychoactive drug use in Turkish
           Republic of Northern Cyprus: 2003-2013

    • Abstract: 2016-06-08T23-15-29Z
      Source: Anatolian Journal of Psychiatry
      Mehmet Çakıcı, Nesli Tutar, Ebru Çakıcı, Meryem Karaaziz, Ayhan Çakıcı.
      Objective: Studies about psychoactive substance use which is becoming more prevalent in the world and threatening humanity have increased. In this study, the results of 2015 substance use prevalence research are compared with 2003 and 2008 studies to examine the course of substance use in TRNC. Methods: The population of this study consists of Turkish speaking individuals who live in Turkish Republic of Northern Cyprus (TRNC) and are between ages of 18-65. The sample of 1040 individuals representing the general population was determined by stratified random sampling method by considering sex, age and geographical area quotas. The data was collected in May and June 2013. The survey form of the study was prepared from ‘European Model Questionnaire’ of Council of Europe. Prevalence results are given compared with the data of 2003 (825 people) and 2008 (804 people) and used the same questionnaire. Results: At least once life-time cigarette use was 62.1% and alcohol use was 68.5%. The lifetime prevalence of any substance use other than cigarette and alcohol was 8.5% while illicit substance use was 8.4%. Illicit substance use rates were 3% in 2003 and 7.7% in 2008. Cannabis and synthetic cannabinoid ‘bonsai’ which had been popular in recent years were found to be the most widely used illicit substances. Conclusion: The study shows that cigarette use in TRNC is higher than the rates of world average and alcohol use rates are parallel to western countries. An important increase in the rates of illicit substance use is found between the years of 2003-2013 in TRNC.

      PubDate: Wed, 08 Jun 2016 00:02:24 GMT
  • Is catatonia a predictive symptom of affective disorders following
           traumatic stress' A case report

    • Abstract: 2016-06-08T23-15-29Z
      Source: Anatolian Journal of Psychiatry
      Çilem Bilginer, Gülşah Baki, Mutlu Karakuş, Sema Kandil.
      Catatonia is a syndrome that is characterized by abnormal body movements, negativism, mutism or disturbances in conscious. During the twentieth century catatonia was accepted as a condition associated with schizophrenia but today it is defined as a separate disorder. Catatonia is a rarely reported condition in children and adolescents and a curable condition with early diagnosis and proper treatment. But it could be a life-threatening disorder if fever and autonomic changes accompany with it. In this report an adolescent diagnosed with catatonia following acute stress disorder and also diagnosed with manic episode in follow-up visits is presented. Thus we aimed to take attention to catatonia that can be neglected in children and adolescents and to follow-up visits of these cases.

      PubDate: Tue, 07 Jun 2016 23:11:57 GMT
  • Menstrual psychosis: a case report

    • Abstract: 2016-06-08T23-15-29Z
      Source: Anatolian Journal of Psychiatry
      Evrim Aktepe, Emel Özen, Funda Özyay Eroğlu.
      Menstrual psychosis (MP) is not a distinct title within the current standard psychiatric classification. Most of the literature on this disorder is based on case reports. Due to its unique clinical symptoms, MP differs from other disorders that come with psychotic symptoms. It has been reported that controlled studies utilizing large samples as well as long-term monitoring are required for the treatment of MP cases. This study presents the case of a female adolescent with MP involving affective and psychotic findings, and it attempts to raise awareness regarding this rare disorder.

      PubDate: Tue, 07 Jun 2016 23:09:28 GMT
  • Psychiatry Journals in Turkey and their Future

    • Abstract: 2016-05-27T23-19-30Z
      Source: Anatolian Journal of Psychiatry
      Lut Tamam.

      PubDate: Thu, 26 May 2016 08:49:29 GMT
  • Fluoxetine induced trichotillomania in a 7-year- old boy: a case report

    • Abstract: 2016-05-27T23-19-30Z
      Source: Anatolian Journal of Psychiatry
      Nurullah Bolat, Mesut Yavuz.
      Trichotillomania (TTM) is a mental disorder characterized by recurrent hair pulling that result in significant hair loss. Traditionally, serotonin has been the principal neurotransmitter implicated in TTM, however, recent literature strongly supports the role of dopamine in the pathophysiology of TTM. Here we describe 7 year old boy who had fluoxetine-induced trichotillomania. According to the temporal association in time between fluoxetine treatment, the symptoms of trichotillomania and the resolution of symptoms in the absence of fluoxetine, hair pulling was likely fluoxetine induced. It is implicated that serotonin reuptake inhibitors may have facilitative effects on dopamine. We suggest that TTM may be the result of dopamine increase due to fluoxetine treatment. To our knowledge this is the first reported case of antidepressant-induced trichotillomania.

      PubDate: Thu, 26 May 2016 08:39:45 GMT
  • Translation of original form of Schutte Emotional Intelligence Test into
           Turkish and examination of its psychometric properties

    • Abstract: 2016-05-27T23-19-30Z
      Source: Anatolian Journal of Psychiatry
      Arkun Tatar, Serdar Tok, Merih Tekin Bender, Gaye Saltukoğlu.
      Objective: The purpose of the present study is to adopt Schutte Self Report Emotional Intelligence Test (SSREIT-33) into Turkish preserving its original factor structure and number of items by applying the test to a heterogeneous participants group representing general population. It is also intended to conduct a research design in accordance with the main features (psychometric properties) of the presentation study. Methods: A total of 1561 people, 839 female, 722 male, ranging in age from 18 to 78 participated in the study. Results: The criterion validity coefficient of the SSREIT-33 total score with Toronto Alexithymia Scale was determined as -0.63, and it was 0.87 with 41 item Revised Schutte Emotional Intelligence Test; and discriminant validity coefficient of SSREI total score with the factors of Short Form Five Factor Personality Inventory was as follows: 0.48 for openness to experience, -0.28 for emotional stability, 0.39 for conscientiousness, 0.16 for agreeableness and 0.11 for extraversion. The test-retest reliability coefficient for 15 and 30 days applications were 0.81 and 0.78 respectively. Confirmatory factor analysis results revealed acceptable fit index values for single factor structure. Internal consistency coefficient of the test was found as 0.86. Conclusion: The values obtained from the form translated into Turkish in this study were quite similar to the values obtained from SSREI-33 presentation study.

      PubDate: Thu, 26 May 2016 06:02:02 GMT
  • Long-term prognosis of commercially sexually exploited youth in Turkey:
           brief report

    • Abstract: 2016-05-27T23-19-30Z
      Source: Anatolian Journal of Psychiatry
      Bengi Semerci, Sarper Taşkıran, Ali Evren Tufan, Işın Şanlı.
      Objective: Factors contribute to commercial sexual exploitation of youth (CSEY) and a variety of physical and psychological consequences of CSEY were previously discussed in the literature. The aim of the current study was to determine the long term prognosis of a sample of CSEY in Turkey. Methods: A sample of 108 CSEY (all females) with a mean age of 16.7±2.7 (range=9-22) years living in a specialized center for protection against perpetrators were examined in terms of their sociodemographic variables, previous abuse history, family history and current psychopathology. Identified cases were referred for psychiatric evaluation. We obtained follow-up data 11 years after initial contact from this cohort (mean age 25.9±2.6 at time of follow-up) with the subjects and received information regarding their current functioning. Results: Follow up data revealed that recommendations during psychiatric follow up could not be acted upon. 71.4% of the initial sample (n=76) could be reached via direct or indirect contacts. We found that good/superior functioning was very rare and that one-third of the sample that could be reached still were being sexually exploited. Important considerations derived from the results were discussed in the current article.

      PubDate: Thu, 26 May 2016 05:58:36 GMT
  • Early diagnosis and treatment of ADHD are important for a secure
           transition to adolescence

    • Abstract: 2016-04-21T20-32-30Z
      Source: Anatolian Journal of Psychiatry
      Oğuzhan Zahmacıoğlu, Emine Zinnur Kılıç.
      Objective: Attention-deficit hyperactivity disorder (ADHD) is one of the most common psychiatric disorders that begins in childhood. By using self-esteem and loneliness scales, our aim was to compare the adolescents who were diagnosed “early” and are currently receiving treatment with the ones with “late” diagnoses. By examining loneliness and self-esteem directly, we wish to emphasize a possibility of positive impact of early diagnosis and treatment. We hypothesized that the duration of treatment is an important factor in reducing several negative psychosocial impacts of ADHD. Methods: The study included 62 adolescent patients with a “late” ADHD diagnosis between the ages of 12 and 14 years, and 55 adolescent patients with “early” diagnosis between the ages of 6 and 8 years who have been followed up regularly with appropriate treatment for nearly 6 years. These groups were compared with regard to self-esteem and feelings of loneliness. Results: The UCLA Loneliness Scale scores were higher, but the Rosenberg Self-esteem Scale scores were lower in the late-diagnosed group. These results did not change with regard to ADHD subtypes and gender. Conclusion: The late-diagnosed adolescents with ADHD feel they are alone more than the early-diagnosed adolescents, and they like themselves less compared to the early-diagnosed group.

      PubDate: Thu, 21 Apr 2016 13:02:26 GMT
  • Impact of alcohol and substabce use by patients with schizophrenia on
           burden, quality of life, anxiety and depression levels of primary

    • Abstract: 2016-04-21T20-32-30Z
      Source: Anatolian Journal of Psychiatry
      Menekşe Sıla Yazar, Ahmet Alper Depçe, Özlem Devrim Balaban, Derya İpekçioğlu, Nezih Eradamlar.
      Aim: Alcohol and substance use are the most common comorbidities among patients with schizophrenia, with significantly higher levels of burden reported among primary caregivers. In this study, we aimed to assess the impact of alcohol and substance use on caregivers, and the effects of the severity of disease symptoms and certain attributes of patients and their primary caregivers on the burden, depressive symptoms, quality of life, and anxiety levels of caregivers. Methods: We recruited 100 patients with schizophrenia according to DSM-IV TR from inpatient clinics of Bakırköy Research and Training Hospital for Psychiatry, Neurology, and Neurosurgery and their primary caregivers from September 2010 to March 2011. The severity of patient symptoms was assessed using the Positive and Negative Syndrome Scale (PANSS). All caregivers completed the Sociodemographic and Clinical data form, The Zarit Burden Scale, Beck Depression Inventory, State-Trait Anxiety Inventory, and WHO Quality of life-BREF. Results: The ages of caregivers and patients were 23–68 and 20–65 years, respectively. The primary caregiver was the patient’s mother in 53% of cases. We found levels of burden that were significantly higher for caregivers of patients with alcohol or substance use, and these were positively correlated with the positive psychotic subscale of PANSS. Caregivers of patients without alcohol and substance use had significantly higher scores for psychological and social relationship domains of WHOQOL-BREF. Discussion: Alcohol and substance use disorder which causing more complicated and severe needs of schizophrenia patients is associated with increased level of caregiver burden, depression and anxiety levels and decreased quality of life. Our findings suggest that there is a significant relationship between caregiver burden and alcohol and substance use by patients with schizophrenia.

      PubDate: Tue, 19 Apr 2016 12:32:33 GMT
  • Translation of Big-Five Personality Questionnaire into Turkish and
           comparing it with Five Factor Personality Inventory Short Form

    • Abstract: 2016-04-21T20-32-30Z
      Source: Anatolian Journal of Psychiatry
      Arkun Tatar.
      Objective: There is not great number of Turkish personality tests developed or adapted based on five factor model. For this reason, Big Five Personality Questionnaire (B5KT-50-Tr) was translated into Turkish. Consequently, B5KT-50-Tr and Five Factor Personality Inventory Short Form (5FPI-SF) were applied to the same group and constructs and factors of these two test were compared by various procedures. In this way we aimed to reveal the similarities and differences of two tests. Methods: The study was carried out in two phases and with two separate studies. In the first phase of the study B5KT-50-Tr was translated into Turkish. A total of 1167 people, 589 women and 578 men ranging in age from 18 to 70 participated in this study. Out of these participants 98 people took part in the test- retest study. In the second phase of the study both tests were administered and the total number of participants were 1463, 786 women and 677 men, ranging in age from 18 to 80. Results: In the translation study B5KT-50-Tr explained 35.58% of the total variance by five factors and CFA results showed model fit. Internal consistencies of the factors of the test were calculated between 0.65 and 0.79, and test-retest coefficients were between 0.55 and 0.80. As for the comparison study, B5KT-50-Tr explained 36.10% of the total variance and 5FPI-SF explained 32.11% of the total variance. According to the results of CFA both tests showed model fit at a close level to each other. Internal consistencies of the factors of B5KT-50-Tr were between 0.68 and 0.79, and for 5FPI-SF were between 0.68 and 0.85. The correlation coefficients of the factors of the two test with each other were found between 0.51 and 0.66. Although there was no difference between IRT item parameter values between two tests, mean factor scores of all factors were found different. Conclusion: Translation study show that B5KT-50-Tr has met the basic psychometric requirements. As for the comparison study, it has been observed that the tests are largely similar in terms of the features compared. The obtained results are discussed in terms of the details.

      PubDate: Tue, 19 Apr 2016 12:30:46 GMT
  • A potential biomarker for bipolar I disorder: serum arginine vasopressin

    • Abstract: 2016-04-21T20-32-30Z
      Source: Anatolian Journal of Psychiatry
      Akif Asdemir, Tayfun Turan, Cengiz Uysal, Eser Kılıç.
      Objective: The neuropeptide arginine vasopressin (AVP) has effects on behavior and stress regulations which are impaired in bipolar disorder (BD). Only a very limited number of studies have investigated AVP levels in bipolar disorder in contrast to depressive disorders. The study aimed to investigate serum AVP levels during the manic, depressive, or remission periods and after treatment response in patients with bipolar I disorder (BD-I) and healthy controls. Methods: The study consisted of 67 patients with BD-I and 24 healthy controls. The patients were in the manic, depressive, or remission periods of BD-I. Serum AVP levels were assayed in the three groups of patients with BD-I and the controls at the study onset. Then, a second measurement of the AVP levels were carried out in the manic or depressive periods after treatment response. The treatment response was defined as a 50% decrease in the Young Mania Rating Scale and the Hamilton Depression Rating Scale scores for manic and depressive episodes, respectively. Results: The main finding was the significantly lower serum AVP levels in BD-I during manic, depressive, or remission periods compared to healthy controls. After-treatment-response serum AVP levels in depressive BD-I patients increased to the levels of healthy controls and became higher than in the remission period of BD-I. Conclusions: The global reduction in serum AVP levels may be an indicator of impaired neuronal function and neuroprogressive deterioration seen in BD. Notably, given the increased AVP levels in major depressive disorder, serum AVP levels may contribute to distinguishing depressive BD-I from major depressive disorder.

      PubDate: Tue, 19 Apr 2016 12:29:40 GMT
  • Emotional schemas accompanying self-harm behaviors among adolescents

    • Abstract: 2016-04-16T20-35-56Z
      Source: Anatolian Journal of Psychiatry
      Kaasım Fatih Yavuz, Nuran Yavuz, Sevinç Ulusoy, Güliz Özgen.
      Objective: The aim of this study is to assess emotion regulation processes in adolescents with self-harm behavior by the emotional schema approach. Methods: The study included 101 adolescents with delibrate self-harm behavior (DSH), 99 adolescents with psychiatric diagnose and treatment without DSH (without DSH) and 99 healthy adolescents as the control group. Adolescents with DSH were asked to complete Sociodemographic Data Form, Self-Harm Behavior Form, and Leahy Emotional Schema Scale (LESS). Other two groups were asked to complete socio-demographic data form and LESS, afterwards these three groups were compared. Data were assessed with chi-square test and one way analysis of variance methods. Results: While suicide attempts, childhood violence and domestic violence were found significantly more in the DSH and without DSH groups, separation from parents and migration history frequency were found significantly higher only in the DSH group according to other two groups. Groups were compared with LESS; and it was found that ‘weakness against emotions’, ‘uncontrollability’, ‘rumination’, ‘seeing emotions as dangerous’, ‘dissimilarity’ and ‘guilt’ subscale’s mean scores were significantly higher in DSH group. Beside these results LESS ‘acceptance of feelings’, ‘consensus’, ‘comprehensibility’ subscales were lower in DSH group. Discussion: These results show that psychological stressors which individuals encountered in developing period, have establishing effects for DSH. Findings of our research support that DSH is one of the maladaptive coping styles for experienced negative emotions. Focusing on the emotion regulation functions of DSH and accompanying emotional schemas, may help dealing with difficulties through treatment.

      PubDate: Tue, 12 Apr 2016 22:24:02 GMT
  • Angioedema associated with atomoxetine: a case report

    • Abstract: 2016-04-16T20-35-56Z
      Source: Anatolian Journal of Psychiatry
      Merve Çıkılı Uytun, Esra Demirci.
      Angioedema can be occur a drug adverse reaction. Drugs such as non-steroidal anti-inflammatory drugs (NSAIDs), antihypertensive drugs, antibiotics, proton pump inhibitors, fibrinolytic agents, estrogens, calcium channel blockers, beta blockers, and psychotropic drugs (such as serotonin reuptake inhibitors-SSRIs) can induce this reaction. In the literature, there are few case reports about angioedema induced by SSRIs and there is no case report related to atomoxetine. Herein we report a case of angioedema which occurred after initiation of atomoxetine in a 9-year-old girl being treated for attention deficit and hyperactivity disorder; the side effect disappeared after discontinuation.

      PubDate: Tue, 12 Apr 2016 22:23:19 GMT
  • Impact of parental consanguinity on clinical features in schizophrenia

    • Abstract: 2016-04-16T20-35-56Z
      Source: Anatolian Journal of Psychiatry
      Tolga Binbay, Deniz Arık Binbay, Halis Ulaş, Berna Binnur Akdede, Köksal Alptekin.
      Objective: The purpose of this study was to evaluate the impact of parental consanguinity on the clinical features in schizophrenia. Methods: The sample of the study was based on DSM-IV schizophrenia patients admitted to Sinop Atatürk State Hospital between 2009 and 2001. Sociodemographic (age, gender, marital status, completed years of education, employment status) and clinical features (family history of psychiatric disorders, age of onset, number of hospitalization), and parental consanguinity were retrieved retrospectively from case registries. Results: A total of 182 patients (51.1% female and mean age 38.8 years) were included. Frequency of any parental consanguinity and first degree cousin marriages were 19.9% and 13.2% respectively. Mean age of onset of schizophrenia was significantly lower among patients with parental consanguinity than patients with no parental consanguinity (22.1 and 25.5 years respectively; t180=2.1, p

      PubDate: Tue, 12 Apr 2016 22:20:13 GMT
  • The frequency of metabolic syndrome in psychiatric patients using
           antidepressant medications

    • Abstract: 2016-04-16T20-35-56Z
      Source: Anatolian Journal of Psychiatry
      Ebru Fındıklı, Filiz İzci, Mehmet Akif Camkurt, Ali Çetinkaya, Hüseyin Avni Fındıklı, Murad Atmaca.
      Objective: There are limited studies investigating the metabolic syndrome (MetS) in patients using antidepressants. This study examines and compares the prevalence of MetS and related factors in psychiatric patients taking various antidepressants at an outpatient clinic. Methods: The study comprised a total of 70 patients using fluoxetine, paroxetine, sertraline, citalopram, escitalopram, clomipramine and venlafaxine aged 18-60 years with depressive and anxiety disorder. MetS rates of patients (according to National Cholesterol Education Program-Adult Treatment Panel III-NCEP III) who met the study criteria were obtained. Results: In our study metabolic syndrome frequency was 32.8% in total patient groups according to NCEP-III criteria. The higher metabolic syndrome frequency was found in drug groups such as clomipramine, paroxetine and venlafaxine groups. The safest drug for metabolic syndrome was fluoxetine as seen in its relevant group. Conclusion: Conventional antidepressants may cause metabolic syndrome which is important for mortality, morbidity and quality of life of psychiatric patients.

      PubDate: Tue, 12 Apr 2016 22:09:31 GMT
  • Sociodemographic features, depression and anxiety in women with life-long

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Evrim Özkorumak Karagüzel, Filiz Civil Arslan, Ahmet Tiryaki, Mehmet Armağan Osmanağaoğlu, Elif Şimşek Kaygusuz.
      Objective: Vaginismus is a female sexual dysfunction with reflex spasm of the muscles around vagina making penile penetration impossible. Many factors such as psychological, social and cultural may cause vaginismus were proposed, but debates are still ongoing. In this study, factors that may be related with vaginismus were studied and compared with controls. Methods: The participants were women with vaginismus without any organic pathology in gynecological examination and healthy controls. Twenty-five women with vaginismus and 25 controls who have no difficulty with vaginal penetration were evaluated by self-reported scales for depression, anxiety and sexual function. Sociodemographic variables were collected for each participants. Results: Women with vaginismus did not differ from controls in sociodemographic characteristics. The women with vaginismus had significantly higher levels of depression and anxiety. Total score of Glombok-Rust Sexual Satisfaction Scale, subscores of vaginismus, satisfaction, avoidance, anorgasmia were significantly higher and level of sexual knowledge was also limited in women with vaginismus. Discussion: Multiple sociodemographic and clinical factors are found associated with vaginismus. Some of the findings are supported by the literature but some are not. This may remind us there are still unclear concerning related factors in vaginismus. So, there is need for further studies in which hypotheses of different etiopathogeneses of vaginismus will be held.

      PubDate: Fri, 01 Apr 2016 11:33:31 GMT
  • The determinants of benzodiazepine prescription at discharge from a
           psychiatric inpatient clinic

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Okan Ekinci, Aslı Ekinci.
      Objective: The present study aimed to explore the clinical and demographic determinants associated with receiving a benzodiazepine (BDZ) at discharge from a psychiatric inpatient clinic. We hypothesized that BDZ prescribing at discharge would be significantly related to specific demographic and clinical features rather than prescriber effects. Methods: This retrospective chart review comprised records of patients who were hospitalized between January 2014 and January 2016. Results: Of the 1017 patients analyzed, 32.9% (n=335) received a BDZ at discharge. The analysis resulted in three models predictive of BDZ prescription at discharge: age, the presence of suicidal attempt and primary diagnosis. We found that there is no impact of prescriber effects on receiving a BDZ at discharge. Conclusion: Our results indicate that BDZs are being prescribed frequently at discharge, and while prescribing appears to be influenced by diagnosis, suicidality and age. Clinicians need to be alert to potential confounders that may be affecting prescribing practices. In addition, the prescribers should take into account for their patient’s diagnosis, some clinical and demographic features when starting a BDZ at inpatient clinic.

      PubDate: Fri, 01 Apr 2016 11:32:02 GMT
  • Psychiatric management of obesity surgery in Turkey: the need for
           consensus and a guideline

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Güzin M. Sevinçer.
      Bariatric surgery operations in Turkey increasingly expands as well as in the world. Growing literature supports that psychiatric and psychosocial assessment of obesity surgery patients are crucial. Many of the weight loss surgery centers applies multidisciplinary approach including psychiatric and psychological assessments. However, a worldwide accepted guideline to manage obesity surgery patients regarding psychiatric and psychosocial assessment, is not available. Instead, there are variety of expert consensus texts are used by different centers which taken into account by the health authorities. Unfortunately, neither expert consensus texts nor a guideline are available yet, in Turkey. Patients, bariatric surgeons and even mental health professionals have been underestimated the importance of psychiatric evaluation in bariatric surgery in Turkey. The main themes to be discussed in this context are the necessity of psychiatric evaluation, assessment methods, qualification and competency of the professionals and the quality of the assessments. Patients should be screened routinely in terms of the presence of eating disorders, mood disorders, substance use disorders and other psychiatric disorders in both pre- and surgical period and those who needed should be follow for further psychiatric evaluation and treatment. Careful psychiatric and psychosocial assessment of the patients is important with regard to the improvement of the quality of life as well as preventing adverse effects on weight loss in the post-operative period. This article is aimed to review the current literature and guidelines in order to explore the main issues in psychiatric aspects of the assessment of bariatric surgery patients. It is also aimed that this article provide an orientation for the guidelines will be prepared in Turkey. This article has focused on the assessment of the common psychiatric conditions before and after bariatric surgery. Effectiveness of the treatments, selection of the interventions and advantages/disadvantages of psychopharmacologic, psychotherapeutic or psychosocial interventions are excluded from the scope of this article. It is obvious that to discuss these issues in the relevant platforms and to develop a guideline, are needed in order to reach a common approach.

      PubDate: Thu, 31 Mar 2016 23:26:07 GMT
  • The world of trauma

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Orhan Doğan.

      PubDate: Mon, 28 Mar 2016 13:20:12 GMT
  • Collectiveness by mimicry and Turk community

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Mehmet Emin Ceylan, Fatma Duygu Kaya, Aslıhan Dönmez, Alper Evrensel.

      PubDate: Mon, 28 Mar 2016 13:19:00 GMT
  • Deep vein thrombosis associated with low dose clozapine

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Taha Can Tuman, Uğur Çakır, Güşah Güçlü, Osman Yıldırım.

      PubDate: Mon, 28 Mar 2016 13:17:10 GMT
  • Olanzapine induced urinary incontinence

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      Taha Can Tuman, Uğur Çakır, Osman Yıldırım.

      PubDate: Mon, 28 Mar 2016 13:15:37 GMT
  • The manuscript titled ‘The relationship between smoking and alcohol
           use and internet addiction among the university students

    • Abstract: 2016-04-01T23-20-43Z
      Source: Anatolian Journal of Psychiatry
      A. Gazi Ünlü, Kayhan Gürbüz.

      PubDate: Mon, 28 Mar 2016 13:14:17 GMT
  • The evaluation of child sexual abuse in child advocacy center: one year
           experience of a single center

    • Abstract: 2016-03-22T21-30-39Z
      Source: Anatolian Journal of Psychiatry
      Özlem Bağ, Sevay Alşen Güney.
      Objective: Child Advocacy Centers (CAC) are multidisciplinary centers that evaluate child sexual abuse (CSA) cases. In Turkey, CACs, first in Ankara, has been established all around the country. This study is conducted to evaluate the CSA cases’ demographic findings, admission types, diagnosis and outcomes in the first year of İzmir CAC. Methods: The data of 943 cases were evaluated retrospectively and 848 child diagnosed as CSA were accepted as the study group. Descriptive statistical analysis were performed. Results: The mean age of the study group was 14.1±3.3 with female/male ratio 5.73. The most common presentation type was sexual abuse due to peer relations of adolescent girls. The most frequent admission type was by law enforcement while the most common presentation by medical services was from psychiatry clinics. The 60% of the study group defined CSA with contact while 27% defined penetration. The perpetrators were frequently (60%) recognized persons before CSA, most of them were friend/boyfriends and darlings. The frequency of incest cases was 10.7%. The most frequent perpetrator of incest cases were fathers. The 99% of perpetrators were males in the study group while 100% in the incest group. Forty eight percent of the study group required forensic examination but the diagnostic value was 32%. Discussion: CACs are functional centers in evaluating child sexual abuse cases in a multidisciplinary approach. As the most common type of admissions is sexual abuse due to peer relations in adolescents, we suggest that preventive social works should focus on this issue.

      PubDate: Tue, 22 Mar 2016 14:21:58 GMT
  • Metacognitive functions in patients who has obsessive compulsive disorder
           and major depressive disorder: a controlled study

    • Abstract: 2016-03-12T19-02-19Z
      Source: Anatolian Journal of Psychiatry
      Seda Yılmaz, Filiz İzci, Osman Mermi, Murad Atmaca.
      Objective: The aim of this study was to compare metacognitive functions of patients with obsessive compulsive disorder (OCD) and major depressive disorder (MDD) and their relationship to clinical symptoms with those of the control group. Methods: The study included 50 patients with OCD and 50 patients with MDD who were admitted to Fırat University, Clinic of Psychiatry and who met the study criteria and 50 healthy controls. The Structured Clinical Interview (SCID-I) for DSM-IV Axis I Disorders, Sociodemographic and Clinical Data Form, and Metacognition Questionnaire-30 (MCQ-30) were administered to patients and control groups; additionally, the Beck Depression Inventory (BDI) and the Beck Anxiety Inventory (BAI) were also administered to patients with MDD whereas the Yale-Brown obsessive compulsive scale (Y-BOCS) and the Obsessive Beliefs Questionnaire-44 (OBS-44) were administered to patients with OCD. Results: Total metacognition scores were found to be significant in both disease groups as compared to the control group. Metacognition subscales of ‘uncontrollability and danger’ and ‘need to control’ were significantly higher in patients with OCD, whereas, the subscale of cognitive confidence was significantly higher in patients with MDD as compared to the control group. In addition, there was a positive correlation between Y-BOCS subscale of compulsion and need to control, between the OBQ-44 factor of perfectionism/certainty and uncontrollability between danger and the subscale of cognitive awareness in patients with OCD. On the other hand, there was a positive correlation between BDI scores and metacognition subscales of positive belief, cognitive confidence and uncontrollability and danger in patients with MDD. Conclusion: The findings of our study demonstrated significant differences in the parameters of metacognition questionnaire between patients with depression and those with OCD. Future studies are warranted to elucidate the causal relationship of these differences to MDD and OCD.

      PubDate: Fri, 11 Mar 2016 23:13:30 GMT
  • Comparison of levels of serum nitric oxide and asymmetric dimethylarginine
           levels in manic episodes in bipolar affective disorder before and after
           the treatment

    • Abstract: 2016-03-12T19-02-19Z
      Source: Anatolian Journal of Psychiatry
      Ahmet Tiryaki, Demet Sağlam Aykut, Evrim Özkorumak Karagüzel, Süleyman Caner Karahan.
      Objective: Function of NO and its intra-system competitive inhibitor of the nitric oxide, asymmetric dimethylarginine (ADMA) has been investigated in mood disorders, schizophrenia, autism, obsessive compulsive disorder and Alzheimer Disorder and significant results were obtained. The mechanism of action in mood stabilizators is still unclear despite many years of studies. The parameters of oxidative stres were shown to decreased upon antimanic treatment in bipolar affective disorder (BAD). The lithium may be suggested to produce neuroprotective effects against oxidative damage by regulatory effects towards various targets. The effects of lithium on nitric oxide synthase were researched in laboratory studies. In this study, two tubes of plasma were taken from the patients for determination of NO and ADMA during manic and euthymic phases. Methods: Seventeen patients who presented to the psychiatry or emergency departments of Farabi Hospital of Karadeniz Technical University and were diagnosed with BAD-I manic episode and followed with lithum were included into the study. The Structured Clinical Interview for DSM-IV Axis I Disorders (SCID-I), Hamilton Depression Rating Scale (HAM-D), Young Mania Rating Scale (YMRS), Montgomery-Asberg Depression Rating Scale (MADRS), were applied. For determination of NO and ADMA levels, two tubes of plasma were collected during the periods of mania and euthymia in the patient group. Results: The level of ADMA were significantly lower while the level of NO were higher in the posttreatment group than the pretreatment group. Conclusion: In this study, the level of NO were increased, the level of ADMA were dicreased in response to lithium treatment, and the therapeutic effect of lithium may contribute this mechanism.

      PubDate: Fri, 11 Mar 2016 23:12:35 GMT
  • Assessment of physical morphological features of typically developing
           siblings of children who were diagnosed with autism spectrum disorder

    • Abstract: 2016-03-12T19-02-19Z
      Source: Anatolian Journal of Psychiatry
      Murat Eyüboğlu, Burak Baykara, Damla Eyüboğlu.
      Objective: The aim of this study was to compare typically developing siblings of children, who were diagnosed with autism spectrum disorders, with typically developing children matched by sociodemographic characteristics, in terms of finger length ratio and hair whorl features and evaluate the concept of the broad autism phenotype. Methods: Forty-one typically developing siblings of 41 cases who were diagnosed autistic disorder, Asperger disorder and pervasive developmental disorder-not otherwise specified according to DSM-IV-TR and 43 controls of typically developing children, who has no history of any psychiatric disorder in their family, were included. Psychiatric diagnostic interview were applied to all children who admitted to the study. The length of the second and fourth fingers of both hands were measured in the study and control group. Hair whorl features of males, who admitted to the study, were assessed in both groups. Conclusion: 2D/4D ratio of both hands were significantly lower in study group. The hair whorls of males in study group were significantly more counterclockwise rotated when compared with control group. Discussion: In our study it is assumed that the findings according to finger ratio were consistent with ‘extreme male brain’ theory, which is identified for autism before. A significant difference of the direction of rotation of hair whorl in males, which is a biological finding of lateralization, indicated that there may be disruptions in the normal development of lateralization in typically developing siblings of autism.

      PubDate: Fri, 11 Mar 2016 23:10:43 GMT
  • Evaluating emotional regulation in children with attention deficit and
           hyperactivity disorder and their mothers

    • Abstract: 2016-03-12T19-02-19Z
      Source: Anatolian Journal of Psychiatry
      Gonca Özyurt, Aynur Akay Pekcanlar, Yusuf öztürk, Burak Baykara, Neslihan İnal Emiroğlu.
      Objective: Attention deficit hyperactivity disorder (ADHD) is one of the most common childhood neurodevelopmental disorder. Due to prior studies, emotion dysregulation can cause externalizing behavior problems and social impairment. Parental factors are important for children’s emotional regulation. We aimed to evaluate emotional dysregulation in children with ADHD and their mothers comparing with controls. Methods: The study group consisted of 62 children (6-12 years old) diagnosed with ADHD. The control group (62 children) comprised patients of other clinics at hospital and was matched for gender and age to the ADHD patients. The Kiddie Schedule for Affective Disorders and Schizophrenia for School Aged Children-Present and Lifetime Version (K-SADS-PL) was used to diagnose ADHD and allowed comorbidities. We evaluated disorder severity at the time of assessment using the Clinic Global Impression Scale (CGI-S). All patients were treatment-naive. Emotional Regulation Checklist (ERC) and child behavior checklist (CBCL) were used to examine children emotional regulation and behavioral profiles. Difficulties in Emotion Regulation Scale (DERS) was used to indicate maternal emotional dysregulation status. Results: There was no significant difference between sociodemographic data of two groups. Children with ADHD had difficulties in anxiety, social functioning, thought problems, attention, aggression and rule breaking areas of CBCL. Mothers of children with ADHD had higher scores in all goals, impulsivity, strategies, and nonacceptance subscales of DERS. Emotional lability scores were statistically significant higher in ADHD group. Conclusion: ADHD generally continues into adolescence and adulthood and multiple functional impairments can be occurred due to ADHD. If the relationship between emotion regulation and ADHD is understood well, treatment of ADHD and emotion dysregulation will be provided easily. Further studies are needed for improving treatment of ADHD and emotion dysregulation.

      PubDate: Fri, 11 Mar 2016 23:08:58 GMT
  • Association between the metabotropic glutamate receptor7 rs3749380
           polymorphism and methylphenidate treatment outcome in children with ADHD

    • Abstract: 2016-03-12T19-02-19Z
      Source: Anatolian Journal of Psychiatry
      Bum-Sung Choi, Bongseog Kim.
      Objective: Attention-deficit/hyperactivity disorder (ADHD) is a heritable neurodevelopmental disorder characterized by inattention, disorganization, and/or hyperactivity-impulsivity. This study investigated the association between the metabotropic glutamate receptors (GRM) 7 rs3749380 polymorphism genotypes and subjective/objective treatment responses to methylphenidate (MPH) in Korean children with ADHD. Methods: This study enrolled 86 medication-naïve children with ADHD in an open-label 8-week trial of MPH. The subjects were genotyped and then evaluated using the ADHD Rating Scale (ARS), the Continuous Performance Test (CPT) and the Clinical Global Impression Scale (CGI) before and after treatment. Results: After 8-week MPH treatment, children with the GRM7 rs3749380 polymorphism T/T genotype had a different response in terms of visual response times and auditory commission errors on the CPT than C/C or C/T genotype groups. Conclusions: These results suggest that the GRM7 rs3749380 polymorphism is associated with the response of MPH in patients with ADHD. Further studies, including replication of our findings using a control or comparison group and a larger sample, are warranted to evaluate the association between the GRM7 genes and treatment responses to MPH in subjects with ADHD.

      PubDate: Fri, 11 Mar 2016 23:08:23 GMT
  • Severity of craving is related with severity of adult ADHD symptoms among
           inpatients with alcohol use disorder

    • Abstract: 2016-03-12T19-02-19Z
      Source: Anatolian Journal of Psychiatry
      Müge Bozkurt, Cüneyt Evren, Gökhan Umut, Ruken Ağaçhanlı, Bilge Evren.
      Objective: The aim of the present study was to evaluate relationship of craving severity with severity of adult attention-deficit/hyperactivity disorder (ADHD) symptoms in a sample of inpatients with alcohol use disorder, while controlling the effects of anxiety and depressive symptoms. Methods: Participants included 78 inpatients with alcohol use disorder. Participants were evaluated with the Obsessive-Compulsive Drinking Scale (OCDS), the Adult ADHD Self-Report Scale (ASRS-v1.1), the State-Trait Anxiety Inventory (STAI) and the Beck Depression Inventory (BDI) after a detoxification period of 3 to 4 weeks. Results: Although trait anxiety predicted OCDS score, trait anxiety was no longer a predictor after entering ASRS-18 score and the ASRS-18 score was the only predictor for severity of craving in linear regression analyses. Results for the ASRS-6 were the same. Among subscales of ASRS-18 inattentive score predicted OCDS score. When obsessive and compulsive dimensions of craving were taken as dependent variables, ASRS-18/ASRS-6 predicted obsessive craving score together with the trait anxiety, whereas ASRS-18/ASRS-6 predicted compulsive craving alone. Conclusion: These findings suggest that severity of ADHD symptoms (particularly inattentive symptoms) is related with severity of the craving. Although ADHD symptoms predicted compulsive craving alone, it predicted obsessive craving together with the trait anxiety. Also ASRS-18 and ASRS-6 showed similar results, suggesting that ASRS-6 with much less items can be used among this population for screening ADHD symptoms.

      PubDate: Fri, 11 Mar 2016 23:03:22 GMT
  • Social psychiatry practices in Turkey from yesterday to today

    • Abstract: 2016-03-02T09-17-52Z
      Source: Anatolian Journal of Psychiatry
      Orhan Doğan.
      Turks have had the social psychiatric practices in very old years. Music therapy, hydrotherapy, occupational therapy, and rehabilitation approaches in Turks are social psychiatry practices. In this article, the social psychiatry practices in the last sixty years in Turkey have been reviewed in various headings such as mental health dispensaries, Psychiatric Crisis Center, association studies, daytime hospitals, epidemiological studies, studies after earthquake, community mental health center, institutional studies, individual studies.

      PubDate: Sat, 27 Feb 2016 11:50:21 GMT
  • The impact of reflective practices on medical students’ attitudes
           towards mental illness

    • Abstract: 2016-02-25T23-16-02Z
      Source: Anatolian Journal of Psychiatry
      Meral Demirören, Meram Can Saka, Yeşim Şenol, Vesile Şentürk, Özge Baysal, Derya Öztuna.
      Objective: This study aimed to examine the impact of reflective practices on the attitudes of the medical students towards mental illnesses and to determine the impact of some variables on the attitude change. Methods: A quasi-experimental study was carried out in two medical schools in Turkey. Educational intervention, included written and verbal reflection practices for student experience in interview with patients during psychiatry clerkship, was applied in intervention groups. The impact was evaluated by collecting data at before and after psychiatry clerkship using Beliefs towards Mental Illness Inventory (BMI) in intervention and control groups. Results: Total 190 students were included in the intervention (51.6%) and (48.4%) control groups. Mean score of total BMI was found to be significantly lower after intervention in both groups, however, no statistical difference was observed between the two groups. The impact of two subscales of the empathy and basic personal traits of the students and self-experience of mental illness on attitude change were found to be statistically significant. After correction was done for these variables, time affect (psychiatry training) could not be found statistically significant. Verbal reflective practice was found to be more beneficial than written one. Discussion: Psychiatry clerkship training created a small and meaningful impact, but reflective practices did not show a significant impact on attitude change of students towards mental illness. Empathy, basic personal traits and self-experience of mental illnesses can be taken into consideration as factors related with stigma in improving attitudes of students.

      PubDate: Sun, 21 Feb 2016 05:00:54 GMT
  • The prevalence of adult separation anxiety disorder in a clinical sample
           of patients with ADHD

    • Abstract: 2016-02-25T23-16-02Z
      Source: Anatolian Journal of Psychiatry
      Eylem Özten, Ali Evren Tufan, Gül Eryılmaz, Gökben Hızlı Sayar, Hüseyin Bulut.
      Objective: Separation anxiety disorder (SAD) of adulthood was added to the group of anxiety disorders in the DSM-5. Attention-deficit/hyperactivity disorder (ADHD) displays elevated comorbidity with anxiety disorders. Aims of the present study are to determine a) the prevalence of SAD in a clinical, adult sample with ADHD and b) the correlates of SAD comorbidity in adults with ADHD. Methods: DSM-IV Based Diagnostic and Evaluation Inventory for Adult ADD/ADHD to confirm ADD/ADHD diagnosis by the psychiatrist, Structured Clinical Interviews for the Symptoms of SAD (SCI-SAS), the Questionnaire for Adult SAD (A-SAQ), and the Inventory for Symptoms of SAD (SASI) were administered to ADHD patients and to the age, gender, marital status, and education-matched healthy controls. Results: Thirty adults with ADHD and 26 healthy controls were enrolled in the study. The ADHD group had significantly higher Adult Separation Anxiety Questionnaire (A-SAQ) and Separation Anxiety Symptom Inventory (SASI) scores than the control group. According to the Structured Clinical Interview for Separation Anxiety Symptoms (SCI-SAS), 53.3% of the ADHD group and 11.5% of the control group fulfilled the SAD criteria while 63.3% and 19.2%, respectively, fulfilled the childhood SAD criteria. Three patients with ADHD (10.0%) that did not fulfil the childhood SAD criteria had the diagnosis as adults, while six ADHD patients (20.0%) and four control patients (15.4%) had childhood SAD and recovered from it. Only one of the controls (3.9%) developed de novo SAD. We found significantly increased life-time, childhood, and adult prevalence of SAD in adult patients with ADHD. Conclusions: Due to the self- selected, clinical sample, this rate may not reflect the true population prevalence of SAD among Turkish adults; community studies evaluating SAD’s prevalence are needed.

      PubDate: Sun, 21 Feb 2016 04:57:10 GMT
  • EEG complexity and frequency in chronic residual schizophrenia

    • Abstract: 2016-02-14T23-18-00Z
      Source: Anatolian Journal of Psychiatry
      Oğuz Tan, Serap Aydın, Gökben Hızlı Sayar, Doğa Gürsoy.
      Objective: Some studies on schizophrenia showed an increased complexity in electroencephalography (EEG) whereas others detected a decreased complexity. Because this discrepancy might be due to the clinical features or complexity measures used, we employed two different complexity measures in a group of schizophrenics similar in illness duration (chronic) and symptom profile (residual). Methods: Right-handed chronic residual schizophrenic patients (10 male, 10 female) and age- and sex-matched 20 healthy controls were included in the study. Eyes-closed resting EEG series were measured through quantitative EEG band activities, the log energy entropy (LEE) values, and the Hurst exponents (HE) of EEG measurements were computed for each electrode site. Results: Significantly higher LEE values in the prefrontal, frontal, temporal and parietal locations were observed in schizophrenic patients compared with controls. HE values were significantly higher on the right frontal area in the schizophrenics. Patient group showed increased prefrontal, frontal and parietal delta activity, prefrontal, left temporal and right parietal theta activity and increased left temporal alpha activity. Discussion: In the present study, we found that chronic residual schizophrenia is associated with decreased complexity and increased smoothness in EEG. In addition, EEG of patients was characterized by obvious slowness at prefrontal and frontotemporal regions, dominantly. An integration of EEG complexity and frequency analysis can be proposed as an innovative tool in schizophrenia research.

      PubDate: Fri, 12 Feb 2016 03:05:14 GMT
  • Metabolic parameters in patients with major depression treated with

    • Abstract: 2016-02-14T23-18-00Z
      Source: Anatolian Journal of Psychiatry
      Onur Okan Demirci, Nurhan Fıstıkcı, Eser Sağaltıcı, Nesrin Karamustafalıoğlu, Abdullah Yıldırım, Mehmet Cem İlnem.
      Objective: The aim of this study is to determine the change in metabolic parameters of patients with major depression treated with escitalopram. Methods: The height, body weight, waist circumference, blood pressure, lipid profile (total cholesterol, low density lipoprotein, high density lipoprotein, triglycerides), fasting blood glucose, thyroid stimulating hormone and Hamilton Depression Scale (HamD) of 41 consecutively selected patients with major depression were measured before treatment and in the third month of treatment, for whom a decision to start treatment with escitalopram was decided. The relationship between treatment and changes in these metabolic parameters were evaluated at the end of this period. Results: The mean age of patients was 30.24±9.96 years. Eleven (27%) patients were male and 30 (73%) were female. Twelve (29.3%) patients were treated with 10 mg/day escitalopram, and 29 patients (70.7%) 20 mg/day. Significant increases were detected in body weight, body mass index, waist circumference and systolic blood pressures of all patients from initiation of treatment to three months. A significant increase was found in the waist circumference of male patients (n=11) after twelve weeks of treatment. Body weight, body mass index, waist circumference, triglycerides, systolic blood pressure were found to be significantly increased after three months of treatment in female patients (n=30) who were treated with escitalopram. HamD scores were found to be significantly decreased after three months in patients treated with escitalopram. Conclusion: Escitalopram caused an increase in especially body weight and waist circumference in patients with major depression.

      PubDate: Fri, 12 Feb 2016 02:59:37 GMT
  • Reliability and validity study of the KIDSCREEN Health-Related Quality of
           Life Questionnaire in a Turkish child and adolescent population

    • Abstract: 2016-02-14T23-18-00Z
      Source: Anatolian Journal of Psychiatry
      Hakan Baydur, Dilek Ergin, Gül Gerçeklioğlu, Erhan Eser.
      Objective: The aim of this study is to adapt KIDSCREEN Health Related Quality of Life (HRQoL) questionnaire into Turkish and to analyze the psychometric properties of the scale. Methods: The study conducted in the city of Manisa located in western Turkey is a validity and reliability study and consisted of 662 children and adolescents between the ages of 8 and 18 and 552 parents. In the study, socio-demographic characteristics of the participants were identified, and KIDSCREEN-52 and KINDL QoL questionnaires were administered. The KIDSCREEN scale was adapted to Turkish and applied psychometric analyses. Results: Cronbach's alpha ranged between 0.69 and 0.95 for the child and adolescent version of the KIDSCREEN-52, KIDSCREEN-27 and KIDSCREEN-10 index and between 0.68 and 0.94 for the proxy version. The results of confirmatory factor analyses fit indices for KIDSCREEN were considered to be at a good level. Correlation coefficient between the dimensions of the KIDSCREEN and KINDL scales assessing similar constructs (ranging between 0.45 and 0.62) were higher than that of other dimensions. In addition, the KIDSCREEN yielded results to discriminate the physical well-being, psychological well-being and perception of insufficient income. Conclusion: Turkish version of the child/adolescent and proxy versions of KIDSCREEN is a valid and reliable measurement tool.

      PubDate: Fri, 12 Feb 2016 02:19:52 GMT
  • A neuroleptic malignant syndrome case with haloperidol depot

    • Abstract: 2016-02-10T04-32-25Z
      Source: Anatolian Journal of Psychiatry
      Hilal Yiğit, Tuğba Mutu, Ertaç Sertaç Örsel, Atila Erol.
      The development of depot antipsychotics are facilitated incompitable patient’s treatment process for in terms of chronic disease course. One of the disadvantages of depot antipsychotics, having various advantages and disadvantages, neuroleptic malignant syndrome (NMS) rate is higher than the oral form. NMS, rare but can be fatal, is an idiosyncratic reaction characterized by confusion, hyperthermia, autonomic dysfunction, muscle rigidity after use of neuroleptics. In this case, a schizophrenia patient used to haloperidol depot, named haldol decanoate in abroad used since1986 (Europe-US) but recently introduced in Turkey, with NMS was reported.

      PubDate: Fri, 05 Feb 2016 11:49:47 GMT
  • The Hwalek-Sengstock Elder Abuse Screening Test: The adaptation study into

    • Abstract: 2016-02-10T04-32-25Z
      Source: Anatolian Journal of Psychiatry
      Emine Özmete.
      Objective: This study is undertaken to adapt The Hwalek-Sengstock Elder Abuse Screening Test (HS-EAST) to Turkish. Methods: The sample of the study is composed of 465 volunteered women and men (60+) (mean age: 71.47±7.4) who live alone in their home or with their children across Turkey. HS-EAST has 15 items. Total point correlation and inner consistency coefficient (KR 20) are calculated for reliability of the scale. Confirmatory factor analysis is performed to test the theoretical suitability and validity for Turkish context. Results: In this study, HS-EAST has three factors construction as original scale. Inner consistency coefficient was found as 0.814. The highness of the score points indicates a potential increase in the risk of elder abuse. Conclusion: These results show that the Turkish version of HS-EAST may be used as a valid and reliable tool in determining elderly abuse and also for purposes of early diagnosis and in other relevant research. It might be recommended that exploring the validity and reliability of the scale is repeated in different groups of subjects of similar ages and that the scale is used in prevalence studies

      PubDate: Fri, 05 Feb 2016 11:45:28 GMT
  • Olfactory reference syndrome: A case report

    • Abstract: 2016-02-10T04-32-25Z
      Source: Anatolian Journal of Psychiatry
      Hüseyin Bulut.
      Olfactory reference syndrome (ORS ) is a delusional disorder of somatic type of characterized by persistent wrong belief that the person has bad odor originating from his/her body . Patients with ORS feel responsible for themselves for the bad odor and shame. Patients often withdraw from the society, they restrict their social and occupational communication. In this report we present a case with a delusion related to bad odor of his body and secondary depressive symptoms who presented significant improvement with the combination of escitalopram and olanzapine.

      PubDate: Fri, 05 Feb 2016 11:43:20 GMT
  • The relationship between migration and substance use on individuals who
           are routed to the substance abuse treatment due to probation act

    • Abstract: 2016-02-10T04-32-25Z
      Source: Anatolian Journal of Psychiatry
      Derya Şaşman Kaylı, A. Ender Altıntoprak, Hande Çelikay, Yeşim BabürKorkmaz, Deniz Kabakçı.
      Objective: Izmir, is one of the major metropolises of Turkey has migration in an increasing scale. Migration is an important fact that determining economic, social, cultural conditions and forming social environment of individuals. This study is about the relationship between migration which determines socio-economic structure and substance use patterns on individuals who applied for the treatment of substance abuse by probation law to the Ege University, Faculty of Medicine and Addiction Clinic. Methods: The study was conducted with 302 people who agree to participate as a volunteer between the date of 01.10.2014-31.03.2015. The questionnaire, developed by the researchers, was used as a data collection tool. The collected data was evaluated in SPSS 15.0 Program and analyzed by chi-square, Fisher’s Exact test and t test. Findings: According to obtained findings, it has been seen that, comparing with natives, immigrants have higher rates on criteria of lower maternal education level, having more than two children, living as a tenant, high sibling number and interfering other crimes. Established relationships were found to be statistically significant. While, among the natives, the most important reason in starting substance use was detected as ‘curiosity’, it has been remarkably seen that among the migrating participants, personal matters as a reason of beginning substance use has a higher rate. This finding shows the differentiation among two groups. Result: Immigrants, settle out of the city and continue their lives in worse conditions than the ones who live in the city center. Therefore, they cannot benefit adequately positive opportunities of city because of environment, family and individual factors. This disadvantaged conditions encompasses immigrants increasingly. The higher rate of involving in other crimes among the participants who immigrated to İzmir shows how this situation relates with crime. For this study, it is expected to contribute the detections of risk for substance use, in order to prevent drug use in determining of public policy, development of regulations needs to be done and take the necessary protective measures.

      PubDate: Fri, 05 Feb 2016 11:24:47 GMT
  • The role of spirituality and forgiveness in childhood trauma

    • Abstract: 2016-02-10T04-32-25Z
      Source: Anatolian Journal of Psychiatry
      Berna Güloğlu, Özlem Karaırmak, Ekin Emiral.
      Objective: Considered as a childhood trauma, neglect and abuse has a negative impact on the mental and physical health of individuals and they also believe that the world they live in is an unsafe, unfair, and meaningless place. It is highly important to examine how the concepts of spirituality and forgiveness occur with the individuals exposed to childhood trauma. Hence, the present study consists of two phases. The aim of the first phase was to investigate the differences among childhood trauma of the participants in terms of gender. The aim of second phase of the study was to assess the differences in spirituality, forgiveness, forgiving others, forgiving self, and forgiving situation among individuals who exposed to childhood trauma. Methods: The study group consists of 536 university students (413 women, 123 men). In the study, short version of the Childhood Trauma Questionnaire (CTQ), Heartland Forgiveness Scale (HFA), and Spirituality Scale (SS) were used. The study findings were analyzed by multivariate analysis of variance (MANOVA). Results: According to findings, gender has a main effect on sexual abuse, physical abuse, emotional neglect, and emotional abuse. Men were exposed much more physical abuse, physical neglect, emotional abuse, emotional neglect, and sexual abuse compared to women. On the other hand, individuals who exposed to childhood trauma have lower scores on total score of spirituality and forgiveness, and subscale scores of forgiving oneself, forgiving others, and forgiving situations compared to individuals who did not exposed to childhood trauma. Discussion: Childhood abuse and neglect among university students who don’t diagnosed clinically were extremely high. It was also understood that childhood abuse and neglect has a negative impact on spirituality, forgiving others, forgiving self, and forgiving situation among individuals who exposed to childhood trauma.

      PubDate: Fri, 05 Feb 2016 11:23:11 GMT
  • The associations of the antipsychotic polypharmacy in schizophrenia
           treatment with the symptoms, side effects and the quality of life

    • Abstract: 2016-01-23T23-34-18Z
      Source: Anatolian Journal of Psychiatry
      Deniz Ceylan, Sinem Yeşilyurt, Berna Binnur Akdede, Zeliha Sayın, Köksal Alptekin.
      Objective: Antipsychotic polypharmacy is widespread in schizophrenia treatment, and it has been observed to become more widespread over the years. However, the benefits of antipsychotic polypharmacy in schizophrenia treatment are controversial. The present study aims to investigate the relationship between antipsychotic polypharmacy and the quality of life. Methods: Ninety two patients who met DSM-IV criteria for schizophrenia were divided into monotherapy (MT) and polypharmacy (PP) groups with respect to their medications. The quality of life was assessed using the Quality of Life Scale (QLS), the severities of symptoms were assessed using the Positive and Negative Syndrome Scale (PANSS) and the Clinical Global Impression Scale, and the side effects of antipsychotics were assessed using the UKU Side Effect Rating Scale. Results: Total QLS scores in the PP group were significantly lower than those in the MP group. The total antipsychotic doses and the frequencies of the side effects including sedation, dystonia, erectile and ejaculation dysfunction were detected to be higher in the PP group in comparison to the MP group. Total QLS scores were found to be significantly subject to the direct influence of total PANSS negative scores. Conclusion: Poorer quality of life, more severe negative symptoms and more frequent antipsychotic side effects were observed in patients who were receiving antipsychotic polypharmacy, in comparison to patients who were receiving antipsychotic monotherapy. The presence of negative symptoms, and consequently lack of improvement in symptoms may lead clinicians to prefer antipsychotic polypharmacy. However, antipsychotic polypharmacy does not bring sufficient improvement in symptoms and quality of life, whereas it leads to higher antipsychotic doses and increased side effects.

      PubDate: Tue, 19 Jan 2016 12:04:01 GMT
  • Turkish version of Facebook Jealousy Questionnaire: reliability and
           validity studies on university students

    • Abstract: 2016-01-23T23-34-18Z
      Source: Anatolian Journal of Psychiatry
      H. Andaç Demirtaş-Madran.
      Objective: The aim of the present study was to develop and assess validity and reliability of the Turkish version of the Facebook Jealousy Questionnaire. Methods: A Turkish version of the Facebook Jealousy Questionnaire was translated to Turkish from English, and then translated back to English. The sample consisted of 307 students from two different universities in Ankara. In order to determine criterion validity of the scale, its correlation with the Turkish version of Romantic Jealousy Scale’s subscale ‘triggers of jealousy’ was used. Results: For determining the reliability and validity of the scale, internal consistency (Cronbach’s alpha), test-retest and corrected item-total correlations, criterion validity were used. Gender, age and some relational differences such as relational satisfaction and attractiveness of the partner were examined. There were only a significant negative correlation between age and Facebook jealousy score. Conclusions: This study supports the one-factor model of the Facebook Jealousy Questionnaire indicated by the original study. Findings demonstrate that the Turkish version of the Facebook Jealousy Questionnaire is a highly reliable and valid instrument to measure Facebook jealousy.

      PubDate: Tue, 19 Jan 2016 12:01:02 GMT
  • Alexithymia levels in patients with unipolar and bipolar depression and
           the effect of alexithymia on both severity of depression symptoms and
           quality of life

    • Abstract: 2016-01-18T23-16-54Z
      Source: Anatolian Journal of Psychiatry
      Şaban Karayağız, Mustafa Baştürk.
      Objective: Aims of this study are to compare the alexithymia scores of patients with unipolar depression (UD), bipolar affective disorder depressive episode (BAD-D) and healthy controls, to explore the effects of alexithymia scores on both severity of depression symptoms and quality of life. Methods: Case group of the study is consisted of one hundred and eighteen UD diagnosed, forty eight BAD-depression diagnosed patients, based on DSM-IV-TR criteria. Control group of the study is consisted of ninety six people who had no history of psychiatric disease. Overall, 262 people had involved in the study. Sociodemographic and Clinical Data Form, Hamilton Rating Scale for Depression (HRDS), Beck Depression Inventory (BDI), Toronto Alexithymia Scale (TAS-20) and SF-36 Quality of Life Scale are used for acquiring information of the patients. Results: Mean of age, gender, marital status, place for living, level of income of UD, BAD-D and control groups were similar. Statistically significant differences were observed in between UD, BAD-D and control groups, in terms of HRDS, TAS-20 and SF-36 scores. Mean group scores of UD and BAD-D group were higher than controls, in terms of all scales. However, mean points of UD and BAD-D groups were similar in terms of four scales. Patients with UD and BAD-D had positive relationship with TAS-20, BRDS and BDI; negative relationship between SF-36, significantly. In conclusion, it is found that alexithymia scores of UD and BAD-D groups were higher; quality of life scores were lower than controls. It is also observed that patients with higher alexithymia scores have more severe depressive symptoms and having a less sense of quality of life. Although our findings indicate that presence of alexithymia is important in depressive disorders, however no difference were found between alexithymia scores in patients with UD and BAD-D. Discussion: Alexithymia scores of all groups had positively related with depression, negatively related with quality of life. Our findings showed that, alexithymia is an important factor to the diagnosis of depressive disorders, however alexithymia is not a marker to make differential diagnosis of BAD-D and UD.

      PubDate: Mon, 18 Jan 2016 02:42:09 GMT
  • The profiles of children pushed to crime who are treated in a regional
           psychiatric hospital in Turkey

    • Abstract: 2016-01-18T23-16-54Z
      Source: Anatolian Journal of Psychiatry
      Nalan Gördeles Beşer, Leyla Baysan Arabacı, Gülçin Uzunoğlu.
      Objective: The study was conducted to determine the profiles of the children pushed into crime who treated in psychiatric hospital between the years of 2010-2014. Methods: The study, designed as a Retrospective cohort, was conducted by examining the file records of 144 adolescents/children pushed into crime. These outpatient or inpatient adolescents / children were treated as forensic case in a Child and Adolescent Psychiatry Inpatient Units in a regional psychiatric hospital between the years of 2010-2014. Results: 79.9% of investigated cases were men and their average age was 15.33±1.54. It was determined that 59.0% of the cases did not attend school while the treatment period because of the legal cause and 13.2% of these cases worked as a laborer before. 65.3 % them living with their family. Of 72.2% adolescents have negative relationship with their family. 11.8% of adolescents fathers’ have alcohol-substance and 4.9% of adolescent fathers’ have abuse and legal problems. 70.8% adolescents have diagnosis of chronic mental illness, 13.9% of them has more than one psychiatric diagnosis. 81.2's% adolescents have committed crimes for the first time and 18.8% of hem has repeated crime stories. It was determined that adolescents who have migration story and bad family relationships in their past involved in the crimes. Conclusion: It was determined that many of the adolescents pushed in to crime have mental disorder, their academic success and parents’ educational level are low , they have past migration story and the adolescents having a negative family relationships commit repetitive crime.

      PubDate: Mon, 18 Jan 2016 02:39:15 GMT
  • Examining psychometric properties of Distress Intolerance Index and
           Cognitive-Behavioral Avoidance Scale

    • Abstract: 2016-01-18T23-16-54Z
      Source: Anatolian Journal of Psychiatry
      Zehra Çakır.
      Objective: The aim of the study is to investigate psychometric features of Distress Intolerance Index (DII), which was developed to identify the golden standard of distress tolerance concept, and Cognitive-Behavioral Avoidance Scale (CBAS), which assesses avoidance multidimensionally, in a university students population. Methods: The study sample consists of 610 undergraduate students from various departments in Hacettepe and Uludağ University (434 female, 71.4%; 176 male, 28.6%). Test-retest reliability was examined in a sample of 92 people. In addition to DII and CBAS, Positive and Negative Affect Scale (PANAS), Penn State Worry Questionnaire (PSWQ), Coping with Stress Scale (CSS), Cognitive Emotion Regulation Questionnaire (CERQ), Brief Symptom Inventory (BSI) and Beck Depression Inventory (BDI) was also applied. Construct validity of the scales was tested via factor analysis, Cronbach’s alpha coefficients and test-retest correlations were calculated to check for reliability, and Pearson correlation analysis was conducted to investigate criterion-related validity. Results: One factor solution was suitable for DII as also recommended in the original form and reliability of the index was estimated as 0.92. Test-retest reliability was 0.86. The analysis for criterion-related validity revealed theoretically expected significant correlations between DII and BDI, PNAS, BSI and PSWQ, ranging from -0.25 to 0.60. Factor analysis for construct validity of CBAS revealed a four factor solution consistent with the original form. Two items in the original form were excluded from the Turkish version. Reliability coefficient was 0.92 for the overall scale and varied between 0.72 and 0.88 for the subscales. Test-retest reliability varied between 0.60 and 0.90. Analysis for criterion-related validity showed expected and significant correlations varying between -0.10 and 0.44 for CBAS subscales and CERQ, CSS subscales and PSWQ, BDI and BSI overall scores. Conclusion: The findings of this study shows that DII and CBAS are valid and reliable scales. This study also provided further evidence to the validity and utility of the DII.

      PubDate: Sun, 17 Jan 2016 22:37:21 GMT
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