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Journal Cover   Acta Informatica Medica
  [SJR: 0.217]   [H-I: 4]   [0 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
   Published by ScopeMed Homepage  [97 journals]
  • Biographical Lexicon of Medical Informatics

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Gjuro Dezelic.
      Author: Prof Izet Masic, MD, PhD Publisher: AVICENA, d.o.o., Sarajevo, year 2015., 300 pages, hard cover. ISBN 978-9958-720-57-4; COBISS.BH-ID 21884422

      PubDate: Thu, 30 Jul 2015 07:25:34 GMT
       
  • 13th International Conference on Informatics, Management and Technology in
           Healthcare, Athens, Greece, 9-11 July, 2015

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Thu, 30 Jul 2015 07:24:23 GMT
       
  • International Joint Meeting EuroMISE 2015 Prague, Czech Republic, June
           16-18, 2015

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Thu, 30 Jul 2015 07:21:18 GMT
       
  • The Most Influential Scientists in the Development of the Medical
           Informatics (7): Shigekoto Kaihara

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Thu, 30 Jul 2015 07:19:39 GMT
       
  • MRI Findings of Talocalcaneal Coalition: Two Case Reports

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Ayşe Umul.
      Introduction: Tarsal coalition is abnormal fusion of two or more tarsal bones and is a common cause of foot pain. There are osseous, cartilaginous and fibrous subtypes. Calcaneonavicular and talocalcaneal coalitions are more frequent. Radiography is the primary diagnostic tool, however CT and MRI are precious examinations for differential diagnosis of osseous /non-osseous coalitions separations. Furthermore, cross-sectional imaging methods indicate the extension and secondary degenerative joint changes. Case reports: The detection of bone marrow of edema in the articulation area is valuable for diagnosis Hereby, we present two cases, 24 years old female and 35 years old male, with the diagnosis of talocalcaneal coaliation. We also discuss MRI and radiographic findings.

      PubDate: Thu, 30 Jul 2015 07:17:18 GMT
       
  • Suggested Minimum Data Set for Speech Therapy Centers Affiliated to Tabriz
           University of Medical Sciences

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Shahla Damanabi, Shawbo Abdolnejad, Gelavizh Karimi.
      Background: The minimum data considered as a conceptual framework, based on the achievement of effectiveness indicators and it ensures to access of precise and clear health data. The aims of the present study were identified and proposed a data element set of speech therapy centers affiliated with Tabriz University of Medical Sciences. Material and Methods: This study that was cross – sectional type, performed in 9 speech therapy clinic from medical university in 2014. Firstly, the minimum data elements set evaluated using the check list in these centers. Using the findings from the first step and survey of internal and external documentation forms, designed a questionnaire containing a minimum data speech therapy files and it shared between 36 Speech therapy experts using 5 options of Likert scale. Validity of questionnaire was examined through its validity and reliability of content by retest. For data analysis, data processing was performed using descriptive statistics by SPSS21 software. Results: The minimum data set for speech therapy were divided into two categories: clinical and administrative data. The Name and surname, date of birth, gender, address, telephone number, date of admission and the number of treatments, the patient’s complaint, the time of occurrence of injury or disorder, reason and age of disease considered as the most important elements for management data and health history. For the most important elements of clinical information were selected Short-term and long-term aims and development of speech history .Conclusion: The design and implementation of suitable data collection of speech therapy for gathering of data, we recommended planning for the control and prevention of speech disorders to providing high quality and good care of patient in speech therapy centers.

      PubDate: Thu, 30 Jul 2015 07:15:54 GMT
       
  • Hemodialysis Adequacy Monitoring Information System: Minimum Data Set and
           Capabilities Required

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Mohamad Jebraeily, Marjan Ghazisaeidi, Reza Safdari, Khadijeh Makhdoomi, Bahlol Rahimi.
      Introduction: In dialysis centers both nephrologists and nurses are faced with the challenge of ensuring reliable and efficient care accordance with the clinical guideline. Hemodialysis adequacy monitoring information system therefore enable the automation of tasks, which ultimately allows doctors and nursing staff more time to dedicate to the individual treatment of patients. Development of the information systems in healthcare has made the use of the Minimum data set inevitable. The purpose of this study was determined MDS and capabilities required in hemodialysis adequacy monitoring information system. Method and materials: This is a cross-sectional survey conducted with participation of 320 nephrology specialists in 2015. Data were collected using an electronic questionnaire which was estimated as both reliable and valid. The data were analyzed by SPSS software descriptive statistics and analytical statistics. Results: Overall 42 data elements were determined as final set in 4 major categories (patient demographics, medical history, treatment plan and hemodialysis adequacy). The most capabilities required of hemodialysis information system were related to calculate of dialysis adequacy Index (4.80), advice optimal dose of dialysis for each patient (4.63), Easy access to information system without restrictions of time and place (4.61), providing alerts when dialysis adequacy index below the standard (4.55) and Interchange to other information systems in hospitals (4.46) respectively. Conclusion: In design and implementation of information systems focus on MDS and identification IS capabilities based on the users’ needs, due to the wide participation users and also the success of the information system. Therefore it is necessary that MDS evaluated carefully with regard to the intended uses of the data. Also information systems based on capabilities the ability to meet the needs of their users.

      PubDate: Thu, 30 Jul 2015 07:13:30 GMT
       
  • Inhibition on JAK-STAT3 Signaling Transduction Cascade Is Taken by
           Bioactive Peptide Alpha-S2 Casein Protein from Goat Ethawah Breed Milk

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Rista Nikmatu Rohmah, Ferlany Hardiyanti, Fatchiyah Fatchiyah.
      Background: RA is a systemic inflammatory disease that causes developing comorbidity conditions. This condition can cause by overproduction of pro-inflammatory cytokine. In a previous study, we have found bioactive peptide CSN1S2 from Ethawah goat milk for anti-inflammatory for repair the ileum destruction. However, the signaling transduction cascade of bioactive peptides inhibits inflammation still not clear yet. Therefore, we analyzed the signaling transduction cascade via JAK-STAT3 pathway by in vivo and in silico. Methods: The ileum was isolated DNA and amplification with specific primer. The sequence was analyzed using the Sanger sequencing method. Modeling 3D-structure was predicted by SWISS-MODEL and virtual interaction was analyzed by docking system using Pymol and Discovery Studio 4.0 software. Results: This study showed that STAT3 has target gene 480bp. The normal group and normal treating- CSN1S2 of goat milk have similarity from gene bank. Whereas, RA group had transversion mutation that the purine change into pyrimidine even cause frameshift mutation. Interestingly, after treating with the CSN1S2 protein of goat milk shows reverse to the normal acid sequence group. Based on in silico study, from eight peptides, only three peptides of CSN1S2 protein, which carried by PePT1 to enter the small intestine. The fragments are PepT1-41-NMAIHPR-47; PepT1-182-KISQYYQK-189 and PepT1-214-TNAIPYVR-221. We have found just one bioactive peptide of f182-KISQYYQK-189 is able bind to STAT3. The energy binding of f182-KISQYYQK-189 and RA-STAT3 amino acid, it was Σ = -402.43 kJ/mol and the energy binding of f182-KISQYYQK-189 and RAS-STAT3 amino acid is decreasing into Σ = -407.09 kJ/mol. Conclusion: This study suggested that the fragment 182-KISQYYQK-189 peptides from Ethawah goat milk may act as an anti-inflammatory agent via JAK-STAT3 signal transduction cascade at the cellular level.

      PubDate: Thu, 30 Jul 2015 07:12:19 GMT
       
  • Regulation by Phloroglucinol of Nrf2/Maf-Mediated Expression of
           Antioxidant Enzymes and Inhibition of Osteoclastogenesis via the
           RANKL/RANK Signaling Pathway: In Silico study

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Agus Hadian Rahim, Bambang Setiawan, Firli Rahmah Primula Dewi, Zairin Noor.
      Introduction: Phloroglucinol is an antioxidant compound with many positive effects on health. The purpose of this study was to determine the role of phloroglucinol in osteoclastogenesis via the RANKL/RANK signaling pathway and the activity of the transcription factor Nrf2. Material and methods: Analysis was performed in silico using the primary method of docking by the use of Hex 8.0 software and Haddock web server. Analysis of interactions was then performed to determine interactions between the ligand and its receptors by using the software LigPlus and LigandScout 3.1. Results: Results indicated that phloroglucinol compound was thought to inhibit osteoclastogenesis via three mechanisms: inhibiting RANKL−RANK interaction, sustaining the RANKL−OPG bond, and increasing the activity of the transcription factor Nrf2.

      PubDate: Thu, 30 Jul 2015 07:10:41 GMT
       
  • Electronic Health Record for Intensive Care based on Usual Windows Based
           Software

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Arnaud Reper, Pascal Reper.
      Background and objectives: In Intensive Care Units, the amount of data to be processed for patients care, the turn over of the patients, the necessity for reliability and for review processes indicate the use of Patient Data Management Systems (PDMS) and electronic health records (EHR). To respond to the needs of an Intensive Care Unit and not to be locked with proprietary software, we developed an EHR based on usual software and components. Methods: The software was designed as a client–server architecture running on the Windows operating system and powered by the access data base system. The client software was developed using Visual Basic interface library. The application offers to the users the following functions: medical notes captures, observations and treatments, nursing charts with administration of medications, scoring systems for classification, and possibilities to encode medical activities for billing processes. Results: Since his deployment in September 2004, the EHR was used to care more than five thousands patients with the expected software reliability and facilitated data management and review processes. Communications with other medical software were not developed from the start, and are realized by the use of basic functionalities communication engine. Further upgrade of the system will include multi-platform support, use of typed language with static analysis, and configurable interface. Conclusion: The developed system based on usual software components was able to respond to the medical needs of the local ICU environment. The use of Windows for development allowed us to customize the software to the preexisting organization and contributed to the acceptability of the whole system.

      PubDate: Thu, 30 Jul 2015 07:08:27 GMT
       
  • Developing an Intelligent System for Diagnosis of Asthma Based on
           Artificial Neural Network

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Behrouz Alizadeh, Reza Safdari, Maryam Zolnoori, Azadeh Bashiri.
      Introduction: Lack of proper diagnosis and inadequate treatment of asthma, leads to physical and financial complications. This study aimed to use data mining techniques and creating a neural network intelligent system for diagnosis of asthma. Methods: The study population is the patients who had visited one of the Lung Clinics in Tehran. Data were analyzed using the SPSS statistical tool and the chi-square Pearson’s coefficient was the basis of decision making for data ranking. The considered neural network is trained using back propagation learning technique. Results: According to the analysis performed by means of SPSS to select the top factors, 13 effective factors were selected, in different performances, data was mixed in various forms, so the different modes was made for training the data and testing networks and in all different modes, the network was able to predict correctly 100% of all cases. Conclusion: Using data mining methods before the design structure of system, aimed to reduce the data dimension and the optimum choice of the data, will lead to a more accurate system. So considering the data mining approaches due to the nature of medical data is necessary.

      PubDate: Thu, 30 Jul 2015 07:07:04 GMT
       
  • The Webometric Status of Isfahan University of Medical Sciences, Iran

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Behjat Taheri, Roghayeh Ghazavi, Arash Zahed, Zahra Otroj, Elahe Mazaheri, Nayere-Sadat Soleimanzade-Najafi.
      Background: Webometrics refers to the quantitative study of science production, application, structure and technology in the cyber environment. Impact analysis, website collaboration, and recognition of core websites are regarded as the most practical advantages of webometrics. Furthermore, webometrics is applied in ranking studies for universities and academic institutes. This serves as an internationally approved means of academic ranking worldwide. Our study aimed to evaluate the webometric status of Isfahan University of Medical Sciences (IUMS) and its place in the Webometric Ranking of World Universities. We also tried to comment on how to improve the university’s webometric rank at national, regional, and international levels. Material and Methods: This was a descriptive cross-sectional study including all websites of Iranian universities. Census sampling was applied to cover all Iranian university websites. Then the websites were evaluated according to the latest criteria for the international webometric ranking methodology (Cyberometric Lab, July 2012) and their webometric rank at the international level as well as the changes in the rank between July 2012 and January 2013 were analyzed. The webometric rank of IUMS was compared with other medical universities at different levels as well. Findings: According to the findings, from July 2012 to January 2013, IUMS webometric rank improved by 707, 5 and 2 at international, national and ministerial levels, respectively. Moreover, the rank of IUMS for openness rose from 4477 to 193 during the mentioned period (∆ 4284). In excellence, the university rank did not change sensibly (1537 /1538). In the same period, the rank in presence shifted from 1137 to 1091. Meanwhile, growth in website impact was negative as the university impact rank declined from 3369 to 3393. Conclusion: It seems that impact as the most influential ranking indicator fails to grow proportionately as other factors of IUMS website. This is potentially due to the content language (Farsi) which is an important barrier to easy retrieval of information by non-Farsi speakers. However, the scientific content and SEO (Search Engine Optimization) standards of the website need serious improvement.

      PubDate: Thu, 30 Jul 2015 07:01:38 GMT
       
  • A Map for Clinical Laboratories Management Indicators in the Intelligent
           Dashboard

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Zahra Azadmanjir, Mashallah Torabi, Reza Safdari, Maryam Bayat, Fatemeh Golmahi.
      Introduction: management challenges of clinical laboratories are more complicated for educational hospital clinical laboratories. Managers can use tools of business intelligence (BI), such as information dashboards that provide the possibility of intelligent decision-making and problem solving about increasing income, reducing spending, utilization management and even improving quality. Critical phase of dashboard design is setting indicators and modeling causal relations between them. The paper describes the process of creating a map for laboratory dashboard. Methods: the study is one part of an action research that begins from 2012 by innovation initiative for implementing laboratory intelligent dashboard. Laboratories management problems were determined in educational hospitals by the brainstorming sessions. Then, with regard to the problems key performance indicators (KPIs) specified. Results: the map of indicators designed in form of three layered. They have a causal relationship so that issues measured in the subsequent layers affect issues measured in the prime layers. Conclusion: the proposed indicator map can be the base of performance monitoring. However, these indicators can be modified to improve during iterations of dashboard designing process.

      PubDate: Thu, 30 Jul 2015 07:00:06 GMT
       
  • Scientific Production of Medical Universities in the West of Iran: a
           Scientometric Analysis

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Masoud Rasolabadi, Shahnaz Khaledi, Fariba Khayati, Marya Maryam Kalhor, Susan Penjvini, Alireza Gharib.
      Introduction: This study aimed to compare scientific production by providing quantitative evaluation of science output in five Western Iranian Medical Universities including Hamedan, Ilam, Kermanshah, Kurdistan and Lorestan University of Medical Sciences using scientometrics indicators based on data indexed in Scopus for period between the years 2010 to 2014. Methods: In this scientometric study data were collected using Scopus database. Both searching and analyzing features of Scopus were used to data retrieval and analysis. We used Scientometrics indicators including number of publications, number of citations, nationalization index (NI), Internationalization Index (INI), H-index, average number of citations per paper, and growth index. Results: Five Western Iranian Universities produced over 3011 articles from 2010 to 2014. These articles were cited 7158 times with an average rate of 4.2 citations per article. H- Index of under study universities are varying from 14 to 30. Ilam University of Medical Sciences had the highest international collaboration with an INI of 0.33 compared to Hamedan and Kermanshah universities with INI of 0.20 and 0.16 respectively. The lowest international collaboration belonged to Lorestan University of Medical Sciences (0.07). The highest Growth Index belonged to Kurdistan University of Medical Sciences (69.7). Conclusion: Although scientific production of five Western Iranian Medical Universities was increasing, but this trend was not stable. To achieve better performance it is recommended that five Western Iranian Universities stabilize their budgeting and investment policies in research.

      PubDate: Thu, 30 Jul 2015 06:58:56 GMT
       
  • Family Medicine Education with Virtual Patients: a Qualitative Study

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Monika Sobocan, Zalika Klemenc-Ketis.
      Objectives: Virtual patients (VP) have been present within the medical education process for some time. Although they are assumed to be of great benefit for student learning, very little is know about student perception and outcomes of learning, especially during the pre-clerkship years. Therefore we have decided to investigate the use of VPs during lectures, which has never been analyzed before, but could present an opportunity for more effective and holistic learning. Methods: This was a qualitative study among the 4th year undergraduate medical students at the Medical Faculty, University of Maribor, Slovenia. Students, after completing 4 virtual patient cases during the semester, were asked to participate in focus groups. Using these focus groups we asked students to provide information about their perceptions of VP cases, their learning, and suggestions for educational improvements. Data was transcribed and analyzed using the grounded theory-based coding method (open coding). Results: Medical students reported having a positive attitude towards virtual patient learning. They perceived them as helpful for filling in knowledge gaps, learning appropriate patient care and clinical reasoning. However, especially within the setting of early clinical learning, students felt the need to discuss their questions with their tutors in order to achieve better learning outcomes. Conclusion: Students on teaching courses feel the need for structured instructor sessions and the integration of VPs in the course planning in order to maximize their learning outcomes.

      PubDate: Thu, 30 Jul 2015 06:57:10 GMT
       
  • Those Responsible for Approving Research Studies Have Poor Knowledge of
           Research Study Design: a Knowledge Assessment of Institutional Review
           Board Members

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Rahul Mhaskar, Elizabeth Barnett Pathak, Sarah Wieten, Thomas M. Guterbock, Ambuj Kumar, Benjamin Djulbegovic.
      Background: Institutional Review Board (IRB) members have a duty to protect the integrity of the research process, but little is known about their basic knowledge of clinical research study designs. Methods: A nationwide sample of IRB members from major US research universities completed a web-based questionnaire consisting of 11 questions focusing on basic knowledge about clinical research study designs. It included questions about randomized controlled trials (RCTs) and other observational research study designs. Potential predictors (age, gender, educational attainment, type of IRB, current IRB membership, years of IRB service, clinical research experience, and self-identification as a scientist) of incorrect answers were evaluated using multivariate logistic regression models. Results: 148 individuals from 36 universities participated. The majority of participants, 68.9% (102/148), were holding a medical or doctoral degree. Overall, only 26.5% (39/148) of participants achieved a perfect score of 11. On the six-question subset addressing RCTs, 46.6% (69/148) had a perfect score. Most individual questions, and the summary model of overall quiz score (perfect vs. not perfect), revealed no significant predictors – indicating that knowledge deficits were not limited to specific subgroups of IRB members. For the RCT knowledge score there was one significant predictor: compared with MDs, IRB members without a doctoral degree were three times as likely to answer at least one RCT question incorrectly (Odds Ratio: 3.00, 95% CI 1.10-8.20). However, even among MD IRB members, 34.1% (14/41) did not achieve a perfect score on the six RCT questions. Conclusions: This first nationwide study of IRB member knowledge about clinical research study designs found significant knowledge deficits. Knowledge deficits were not limited to laypersons or community advocate members of IRBs, as previously suggested. Akin to widespread ethical training requirements for clinical researchers, IRB members should undergo systematic training on clinical research designs.

      PubDate: Thu, 30 Jul 2015 06:53:12 GMT
       
  • In Memoriam on Assa Reichert (1943 - 2015)

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Tue, 26 May 2015 03:58:23 GMT
       
  • The Most Influential Scientists in the Development of Medical Informatics
           (6): Heinz Zemanek

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Tue, 26 May 2015 03:55:34 GMT
       
  • Dermatoglyphics and Reproductive Risk in a Family with Robertsonian
           Translocation 14q;21q

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Selim Kolgeci, Jehona Kolgeci, Mehmedali Azemi, Aferdita Daka, Ruke Shala-Beqiraj, Ilir Kurtishi, Mentor Sopjani.
      Aim: The present study is carried out to evaluate the risk of giving birth to children with Down syndrome in a family with Robertsonian translocation 14q;21q, and to find the dermatoglyphic changes present in carriers of this translocation. Methods: Cytogenetics diagnosis has been made according to Moorhead and Seabright method, while the analysis of prints (dermatoglyphics analysis) was made with the Cummins and Midlo method. Results: Cytogenetic diagnosis has been made in a couple who suffered the spontaneous miscarriages and children with Down syndrome. Robertsonian translocation between chromosomes 14 and 21 (45, XX, der (14; 21) (q10; q10)) was found in a female partner who had four pregnancies, in two of which was found fetus karyotype with trisomy in chromosome 21 and pregnancies were terminated. The outcome of fourth pregnancy was twin birth, one of them with normal karyotype and another with Down syndrome due to Robertsonian translocation inherited by mother side. Specific dermatoglyphics traits are found in the child carrying Down syndrome, whereas several traits of dermatoglyphics characteristic of Down syndrome have been displayed among the silent carriers of Robertsonian translocation 14q;21q. Conclusion: Robertsonian translocation found in female partner was the cause of spontaneous miscarriages, of giving birth to a child with Down syndrome, and of trisomy of chromosome 21 due to translocation in two pregnancies.

      PubDate: Tue, 26 May 2015 03:53:51 GMT
       
  • Successful Implantation of Bipolar Epicardial Leads and Dual Chamber
           Pacemaker in Infant After Postoperative Atrioventricular Heart Block

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Edin Omerbasic, Ilirijana Haxhibeqiri Karabdic, Elnur Tahirovic.
      Total atrioventricular (AV) block is inconvenient and serious complication of open heart surgery. Permanent total AV block requires the implantation of permanent pacemaker in order to allow normal hemodynamics and patient's survival. In infancy additional challenge is the surgical approach, the selection of electrodes and PM, as well as place of implantation. We are publishing case report of successful double-chamber DDD pacemaker implantation at an infant born with Fallot tetralogy and with low birth weight due to complete AV block after primary surgical correction of these congenital defects.

      PubDate: Tue, 26 May 2015 03:48:35 GMT
       
  • Information Retrieval in Telemedicine: a Comparative Study on
           Bibliographic Databases

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Maryam Ahmadi, Roghayeh Ershad Sarabi, Roohangiz Jamshidi Orak, Kambiz Bahaadinbeigy.
      Background and Aims: The first step in each systematic review is selection of the most valid database that can provide the highest number of relevant references. This study was carried out to determine the most suitable database for information retrieval in telemedicine field. Methods: Cinhal, PubMed, Web of Science and Scopus databases were searched for telemedicine matched with Education, cost benefit and patient satisfaction. After analysis of the obtained results, the accuracy coefficient, sensitivity, uniqueness and overlap of databases were calculated. Results: The studied databases differed in the number of retrieved articles. PubMed was identified as the most suitable database for retrieving information on the selected topics with the accuracy and sensitivity ratios of 50.7% and 61.4% respectively. The uniqueness percent of retrieved articles ranged from 38% for Pubmed to 3.0% for Cinhal. The highest overlap rate (18.6%) was found between PubMed and Web of Science. Less than 1% of articles have been indexed in all searched databases. Conclusion: PubMed is suggested as the most suitable database for starting search in telemedicine and after PubMed, Scopus and Web of Science can retrieve about 90% of the relevant articles.

      PubDate: Tue, 26 May 2015 03:46:59 GMT
       
  • Education and Training for Major Incidents Through Medical Response to
           Major Incidents–MRMI course

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Josip Samardzic, Boris Hreckovski, Ismar Hasukic.
      Incidence of major incidents nowadays is in constant growth, especially in last decade. Main goal of all health systems is to minimize and prevent tragic outcomes of major incidents, thus reducing morbidity and mortality and psychological and physical suffering. Lessons learned from Major Incidents throughout the World point out that tragical outcomes could be avoided through adequate preparation and planning. Necessity to plan and to educate to response to Major incident is greater than ever. Finally it is legal obligation that every hospital has plan in case of Major Incident. Effective planning must incorporate: identification of risks, methods of prevention, identification of all recourses, anticipation of errors and detailed protocol of response for each participant. Knowledge and skills needed for Major incident situations must be adopted through interactive training and practical exercise („learning by doing„). That can be achieved by field exercises and by simulation model. Simulation model has many advantages and enables simultaneous education and training of all participants; scene, transport, hospitals, communication and command which than can be evaluated through objective outcomes. The goal is to train medical staff in real time, on position they are assigned to, with available resources in conditions of Major incident.

      PubDate: Tue, 26 May 2015 03:45:42 GMT
       
  • Data Standards in Tele-radiology

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Mansoor Fatehi, Reza Safdari, Marjan Ghazisaeidi, Mohamad Jebraeily, Mahdi Habibi-koolaee.
      Data standards play an important role to provide interoperability among different system. As other applications of telemedicine, the tele-radiology needs these standards to work properly. In this article, we conducted a review to introduce some data standards about tele-radiology. By searching PUBMED and Google Scholar database, we find more relevant articles about data standards in tele-radiology. Three categories of standards identified, including data interchange, document and terminology standards. Data interchange standards, including those which facilitate the understanding of the format of a massage between systems, such as DICOM and HL7. Document standards, including those which facilitate the contents of a massage, such as DICOM SR and HL7 CDA. And terminology standards, including those which facilitate the understanding of concepts of the domain. Since, the harmonization between different standards are important to meet interoperability, so the more effort is needed to conduct harmonization between tele-radiology standards and other domain.

      PubDate: Tue, 26 May 2015 03:44:13 GMT
       
  • Diabetes Research in Iran: a Scientometric Analysis of Publications Output

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Masoud Rasolabadi, Shahnaz Khaledi, Marlin Ardalan, Marya Maryam Kalhor, Susan Penjvini, Alireza Gharib.
      Introduction: In the developing countries, diabetes mellitus as a chronic diseases, have replaced infectious diseases as the main causes of morbidity and mortality. International Diabetes Federation (IDF) recently estimates 382 million people have diabetes globally and more than 34.6 million people in the Middle East Region and this number will increase to 67.9 million by 2035. The aim of this study was to analyze Iran’s research performance on diabetes in national and international context. Methods: This Scientometric analysis is based on the Iranian publication data in diabetes research retrieved from the Scopus citation database till the end of 2014. The string used to retrieve the data was developed using “diabetes” keyword in title, abstract and keywords, and finally Iran in the affiliation field was our main string. Results: Iran’s cumulative publication output in diabetes research consisted of 4425 papers from 1968 to 2014, with an average number of 96.2 papers per year and an annual average growth rate of 25.5%. Iran ranked 25th place with 4425 papers among top 25 countries with a global share of 0.72 %. Average of Iran’s publication output was 6.19 citations per paper. The average citation per paper for Iranian publications in diabetes research increased from 1.63 during 1968-1999 to 10.42 for 2014. Conclusions: Although diabetic population of Iran is increasing, number of diabetes research is not remarkable. International Diabetes Federation suggested increased funding for research in diabetes in Iran for cost-effective diabetes prevention and treatment. In addition to universal and comprehensive services for diabetes care and treatment provided by Iranian health care system, Iranian policy makers should invest more on diabetes research.

      PubDate: Tue, 26 May 2015 03:42:49 GMT
       
  • Barriers to Research Activities from the Perspective of the Students of
           Isfahan University of Medical Sciences

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Hasan Ashrafi-rizi, Zarmehr Fateme, Zahra Ghazavi Khorasgani, Zahra Kazempour, Sona Taebi Imani.
      Introduction: Necessity to establish a coherent and targeted research context in order to development of any country is increasingly important. But the basic step in creating an effective research context would be enrichment motivation of researchers especially students and resolve barriers of research. Therefore, the purpose of this study was to determine barriers of research activities from the perspective of students of Isfahan University of Medical Sciences. Methods: This is research. Data was collected with author made questionnaire. The study sample consisted of students from Isfahan medical university and sample size based on Krejcie and Morgan table was 357. Sampling was Stratified Random. The validity of questionnaire confirmed by Library and information professionals and reliability based on Cronbach`s Alpha was 0.933, respectively. The type of descriptive statistics was (percentage, frequency and mean) and inferential statistics (T-test, ANOVA, one-Sample Statistics) and SPSS software was used. Findings: Results showed that the mean of barriers to research activities among students of Isfahan University of Medical Sciences was 3.89 ± 0. 483. The highest mean was related to density of students’ curriculum (4.22± 0.968) and lowest mean related to lack of access to appropriate library resources. Also, the mean of research activities `s barriers, according to aspects showed that the mean in individual barriers level (4.06±0.635) was more than other aspects: social and cultural aspects (4.01± 0.661), economical aspect (4.04± 0.787) and organizational barriers (3.78±0.503) . The lowest mean was related to organizational barriers. Also there is no difference between mean of research activities’ barriers of student of Isfahan University of Medical Sciences with regarded of gender, level of education and college. Conclusion: According to results of this research , although, the main barriers between students was individual barriers such as: lack of sufficient familiarity with research methods, insufficient experience in research and lack of familiarity with the terms of the articles in publication , but other aspects like economic, cultural , social and organizational was in bad condition too. Therefore it is suggested that workshops related to research methodologies is executed, like proposal writing, writing articles in university especially for students and administrators support student`s research activities , effectively.

      PubDate: Tue, 26 May 2015 03:41:22 GMT
       
  • Real Time Recognition of Heart Attack in a Smart Phone

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Mahshid Zomorodi Rad, Saeed Rahati Ghuchani, Kambiz Bahaadinbeigy, Mohammad Mahdi Khalilzadeh.
      Background: In many countries, including our own, cardiovascular disease is the most common cause of mortality and morbidity. Myocardial infarction (heart attack) is of particular importance in heart disease as well as time and type of reaction to acute myocardial infarction and these can be a determining factor in patients’ outcome. Methods: In order to reduce physician attendance time and keep patients informed about their condition, the smart phone as a common communication device has been used to process data and determine patients’ ECG signals. For ECG signal analysis, we used time domain methods for extracting the ST-segment as the most important feature of the signal to detect myocardial infarction and the thresholding methods and linear classifiers by LabVIEW Mobile Module were used to determine signal risk. Results: The sensitivity and specificity as criteria to evaluate the algorithm were 98% and 93.3% respectively in real time. Conclusions: This algorithm, because of the low computational load and high speed, makes it possible to run in a smart phone. Using Bluetooth to send the data from a portable monitoring system to a smart phone facilitates the real time applications. By using this program on the patient’s mobile, timely detection of infarction so to inform patients is possible and mobile services such as SMS and calling for a physician’s consultation can be done.

      PubDate: Tue, 26 May 2015 03:38:09 GMT
       
  • The Influence of Aortic Valve Replacement on Functional Moderate -
           To-Severe Mitral Regurgitation in Patients with Aortic Valve Stenosis

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Sejla Sehovic, Adnana Talic, Mirsad Kacila, Elnur Tahirovic.
      Goal: The aim of this study was to show whether the concomitant functional mitral regurgitation in patients undergoing aortic valve replacement improves after this surgical procedure and to identify preoperative echocardiographic parameters that may influence the lack of improvement in mitral regurgitation (MR) after aortic valve replacement (AVR).Material and methods: The study included 45 patients with severe aortic stenosis and concomitant moderate to severe (+2/+3)mitral regurgitation. Results: The results of our study indicated an improvement in the degree of mitral regurgitation in 24 patients. The most prominent parameters responsible for the lack of improvement of mitral regurgitation in our study were LVIDd, ERO, RVol, pulmonary artery systolic pressure and left atrial diameter. Identification of echocardiographic predictors may assist in selection of patients for whom more aggressive surgical treatment is advised. Conclusion: Concomitant moderate to severe functional MR indicates that MV should be repaired or replaced at the time of aortic valve surgery where at least two of indicated predicted preoperative echocardiographic parameters are present.

      PubDate: Tue, 26 May 2015 03:36:41 GMT
       
  • Relationship Between Psychological Empowerment and Productivity of Medical
           Librarians

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Maliheh Zare, Fateme Zarmehr, Hasan Ashrafi-rizi.
      Introduction: Psychological empowerment is really important and has remarkable effect on different organizational variables such as job satisfaction, organizational commitment, productivity, etc. So the aim of this study was to investigate the relationship between psychological empowerment and productivity of Librarians in Isfahan Medical University. Methods: This was correlational research. Data were collected through two questionnaires. Psychological empowerment questionnaire and the manpower productivity questionnaire of Gold. Smith Hersey which their content validity was confirmed by experts and their reliability was obtained by using Cronbach’s Alpha coefficient, 0.89 and 0.9 respectively. Due to limited statistical population, did not used sampling and review was taken via census. So 76 number of librarians were evaluated. Information were reported on both descriptive and inferential statistics (correlation coefficient tests Pearson, Spearman, T-test, ANOVA), and analyzed by using the SPSS19 software. Findings: In our study, the trust between partners and efficacy with productivity had the highest correlation. Also there was a direct relationship between psychological empowerment and the productivity of labor (r =0.204). In other words, with rising of mean score of psychological empowerment, the mean score of efficiency increase too. Conclusions: The results showed that if development programs of librarian’s psychological empowerment increase in order to their productivity, librarians carry out their duties with better sense. Also with using the capabilities of librarians, the development of creativity with happen and organizational productivity will increase.

      PubDate: Tue, 26 May 2015 03:35:17 GMT
       
  • Development of a Fuzzy Decision Support System to Determine the Severity
           of Obstructive Pulmonary in Chemical Injured Victims

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Taha Samad-Soltani, Mostafa Ghanei, Mostafa Langarizadeh.
      Background: Chronic Obstructive Pulmonary Disease (COPD) is the most common known complication of exposure to mustard gas. Thus, all clinical guidelines have provided some recommendation for diagnosis, clinical management and treatment of this disease. Decision support systems are used to increase the acceptance of clinical guidelines. The purpose of this research is to develop a CDSS to determine the severity of COPD in chemical injured victims. Objectives: Development of a decision support system to determine the severity of COPD. Patients and Methods: First, the variables influencing to determining the severity of the disease was classified through studying the clinical guidelines. Then, the fuzzy model was implemented. To testing the system, the data from 50 patients were used. Results: the overall accuracy in determining the severity of the injury is equal to 92%, these indicators reflect the proper functioning of the system to assist the physician regarding the diagnosis of chronic obstructive pulmonary disease and determining its severity. Conclusions: The CDSS has efficient results and satisfactory performance. Although, the medical expert systems cannot be expected to provide 100 percent correct responses, however, they can be useful in the areas of patient management, diagnosis and treatment planning.

      PubDate: Tue, 26 May 2015 03:33:47 GMT
       
  • Evaluation of Biocompatibility of Root Canal Sealers on L929 Fibroblasts
           with Multiscan EX Spectrophotometer

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Alma Konjhodzic-Prcic, Selma Jakupovic, Lajla Hasic- Brankovic, Amra Vukovic.
      Introduction: The purpose of the current study was to estimate the biocompatibility of endodontic sealers with different bases on L929 mouse fibroblasts permanent cell line using Multiscan EX Spectrophotometer. Materials and Methods: Endodontics sealers used in this study were GuttaFlow (Roeko) silicone based sealer, AH plus (De Tray-DENTSPLY) epoxy resin based, Apexit (Vivadent) calcium hydroxide based and Endorez (Ultradent) methacrylate based sealer. Sealer were tested trough time, freshly mixed 24 h, 48h and 7 days after setting. Biocompatibility was determinate on permanent cell lines L929 mouse fibroblasts trough cytotoxicity using MTT assay. Level of absorption was measured with multi scan EX spectrophotometer on length 420-600 nm. Results: Sealer based on calcium hydroxide Apexit Plus, GuttaFlow silicone based sealer and AH plus epoxy resin based sealer, have shown a low cytotoxicity through the all periods of time on culture of L292 mouse fibroblasts. Methacrylate based sealer, Endorez showed moderate cytotoxicity when freshly mixed and after 7 days. After 24 hours the visibility of the cells was 74,0% and after 48 hours 65,1%. which is slightly cytotoxic. Conclusions: According to results of this study there is a statistically significant difference among the groups p

      PubDate: Tue, 26 May 2015 03:32:33 GMT
       
  • Correlation of Parathormone and the Serum Values of Acidum Uricum with
           Calcium Nephrolithiasis Examined by Three Different Methods of Diagnostics
           

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Snjezana Milicevic, Radojka Bijelic, Branislava Jakovljevic.
      Introduction. Urolithiasis is a multifactorial disease. Changes in social and economic living conditions have generated changes in chemical composition of urolith too. Although calcium is a predominant crystalline constituent of kidney stones in 80% of cases, metabolic disorders are not the main reason for their formation. Hyperparathyroidism may be a cause of occurrence of calcium lithiasis, however, the biggest number of its occurrence is not a consequence of elevated values of parathormone. Acid uric has a pervasive presence in all body fluids. The serum level of acid uric is determined by its rate of synthesis, rate of excretion by kidney and gastrointestinal tract, and metabolism. Goal. The goal of our study is to determine a correlation of calcium lithiasis of the upper part of the urinary tract with the parathormone values and the concomitant values of acidum uricum. Material and methods. The study was prospective and included 120 patients with calcium lithiasis of the upper part of urinary tract, divided in three age categories, 20-40 years, 40-60 years and older than 60 years. The diagnosis of calcium lithiasis of the upper part of the urinary tract was made on the basis of urinary tract ultrasonography, and kidney-ureter-bladder radiography (KUB) /intravenous urography (IVU), urine culture and chemical analysis of stone with patients who had a spontaneous emission of stone or following some of the methods for active removal of stone; with some patients non-contrast (NCCT) was carried out too. All patients were subjected to the laboratory analysis of the serum level of acidum uricum and parathormone. Results. With observed 120 patients suffering from calcium urolithiasis, who belonged to adult population, no patient had an elevated value of parathormone, while three patients (2.5%) had the values of acidum uricum higher than the reference values. The average value (for both parameters) was the lowest with the youngest patients and vice versa, and only in the group of 40 to 60 years of age there were patients whose values of the acidum uricum parameter was outside the interval of reference values; the other age groups did not have such values. Based on the analysis of the variance, as a statistical method, it was determined that the average values of acidum uricum in different age groups were statistically significantly different, which is not the case for the parameter parathormone. (p>0,05). Conclusion. The biggest number of nephrolithiasis is not a consequence of elevated values of parathormone. Hyperuricosemia may be present with calcium urolithiasis, without participation in forming kidney stones, most probably as an indirect sign of the existence of the initial insulin resistance and metabolic disease.

      PubDate: Tue, 26 May 2015 03:31:21 GMT
       
  • History of Medical Informatics

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Zekerijah Sabanovic.


      PubDate: Tue, 14 Apr 2015 03:09:34 GMT
       
  • The Most Influential Scientists in the Development of Medical Informatics
           (5): Charles Edwin Molnar

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Tue, 14 Apr 2015 03:08:23 GMT
       
  • Is the Mean H-index of 38.5 Right for 40 Researchers'

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Huseyin Bayramlar, Remzi Karadag.


      PubDate: Tue, 14 Apr 2015 03:06:58 GMT
       
  • A Rare Case of Biliary Leakage After Laparoscopic
           Cholecystectomy–Diagnostic Evaluation and Nonsurgical Treatment: a
           Case Report

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Zlatan Mehmedovic, Majda Mehmedovic, Jasmin Hasanovic.
      Although laparoscopic cholecystectomy has become a gold standard in treatment of symptomatic cholelithiasis, it is associated with higher risk of intraoperative lesions and primarily lesions of biliary ducts. In small percentage of cases biliary fistulas occur, most commonly after leakage from cystic duct stump or accessory bile ducts – Luschka’s duct. We report of a patient who had episodes of abdominal pain following routine laparoscopic cholecystectomy for acute calculous gallbladder. Results of conducted diagnostics verify the presence of biliary fistula caused by obstruction of bile pathways by stagnant pus and microcalculi of common bile duct, with development of biloma presumably caused by pressure injection of contrast material during ERCP procedure. Endoscopic sphincterectomy via ERCP enabled healing of formed biliary fistula, whilst continuous percutaneous ultrasound guided drainage of biloma was method of choice in later treatment of our patient. It is important to note that diagnostic evaluation of biliary fistula is very challenging and that timely nonsurgical treatment is of great benefit for patient.

      PubDate: Tue, 14 Apr 2015 03:05:53 GMT
       
  • Bathing Epilepsy: Report of Three Caucasian Cases

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Florian Dashi, Arsen Seferi, Arben Rroji, Eugen Enesi, Mentor Petrela.
      Introduction: Bathing epilepsy is a specific type of reflex epilepsy triggered by domestic bathing in water. It is a geographically specific epilepsy syndrome that is more prevalent in India Cases in Caucasian population are very rarely reported. These cases share many similar clinical features and a similar prognosis to the Indian cases. Case report: We describe three cases of bathing epilepsy in Albanian population; two cases with well controlled seizures and one with drug-resistant seizures.

      PubDate: Tue, 14 Apr 2015 03:03:27 GMT
       
  • Information Technology – a Tool for Development of the Teaching
           Process at the Faculty of Medicine, University of Sarajevo

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Izet Masic, Edin Begic.
      Introduction: Information Technologies, taking slow steps, have found its application in the teaching process of Faculty of Medicine, University of Sarajevo. Online availability of the teaching content is mainly intended for users of the Bologna process. Aim: The aim was to present the level of use of information technologies at the Faculty of Medicine, University of Sarajevo, comparing two systems, old system and the Bologna process, and to present new ways of improving the teaching process, using information technology. Material and methods: The study included the period from 2012 to 2014, and included 365 students from the old system and the Bologna Process. Study had prospective character. Results: Students of the old system are older than students of the Bologna process. In both systems higher number of female students is significantly present. All students have their own computers, usually using the Office software package and web browsers. Visits of social networks were the most common reason for which they used computers. On question if they know to work with databases, 14.6% of students of the old system responded positively and 26.2% of students of the Bologna process answered the same. Students feel that working with databases is necessary to work in primary health care. On the question of the degree of computerization at the university, there were significant differences between the two systems (p

      PubDate: Tue, 14 Apr 2015 03:01:41 GMT
       
  • Nurses Readiness and Electronic Health Records

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Mahdi Habibi-Koolaee, Reza Safdari, Hamid Bouraghi.
      Background: The importance of the electronic health records in health care well known to everybody, as well as, the role of nurses to provide clinical care; they have a valuable role in successful implementation of electronic systems. The aim of this paper is to assess the nurses’ readiness for EHR implementation. Methods and Materials: This was a descriptive cross sectional study, conducted in 2013. Using cluster sampling, 310 nurses selected from teaching hospitals at Tehran University of Medical Sciences (TUMS). A self-structured questionnaire was used for gathering data. Data management and analysis was performed using SPSS for windows by using descriptive statistics. Results: 85.9% of nurses, participated in the study. The Microsoft Word (58.8%) was the higher level of skill according to ICDL. The mean of computer skills, knowledge and attitude of nurses towards EHR was 43.4%, 51.2% and 65.2%, respectively. In overall, the mean of readiness of nurses was 57.2%. Establish proper communication among providers and prevent duplications was the most positive attitude and complexity of service delivery was the most negative attitude toward EHR. Conclusion: The most obvious finding to emerge from this study is that it should be considered in the education, training and participation of nurses, it should be ensured the level of knowledge and attitude toward EHR and finally, some related courses in Health Information Systems suggested including the curriculum of nursing.

      PubDate: Tue, 14 Apr 2015 02:59:15 GMT
       
  • Electronic Health Records: Critical Success Factors in Implementation

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Reza Safdari, Marjan Ghazisaeidi, Mohamad Jebraeily.
      Introduction: EHR implementation results in the improved quality of care, customer-orientation and timely access to complete information. Despite the potential benefits of EHR, its implementation is a difficult and complex task whose success depends on many factors. The purpose of this research is indeed to identify the key success factors of EHR. Method and materials: This is a cross-sectional survey conducted with participation of 340 work forces from different types of job from Hospitals of TUMS in 2014. Data were collected using a self-structured questionnaire which was estimated as both reliable and valid. The data were analyzed by SPSS software descriptive statistics and analytical statistics. Results: 58.2% of respondents were female and their mean age and work experience were 37.7 and 11.2 years, respectively and most respondents (52.5%) was bachelor. In terms of job, the maximum rate was related to nursing (33 %) and physician (21 %). the main category of critical success factors in Implementation EHRs, the highest rate related to Project Management (4.62) and lowest related to Organizational factors (3.98). Conclusion: success in implementation EHRs requirement more centralization to project management and human factors. Therefore must be Creating to EHR roadmap implementation, establishment teamwork to participation of end-users and select prepare leadership, users obtains sufficient training to use of system and also prepare support from maintain and promotion system.

      PubDate: Tue, 14 Apr 2015 02:55:40 GMT
       
  • Determining the Awareness and Attitude of Employees in Deputy of Health of
           Isfahan University of Medical Science toward Telemedicine and its
           Advantages

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Hamid Keshvari, Asefeh Haddadpoor, Behjat Taheri, Mehran Nasri.
      Introduction: The useful capabilities of information and communication technologies for improving health services are becoming widely known. However many of the managers and policymakers of health systems are not yet familiar with these technologies, their dimensions and applications and the advantages of these new technologies for creating added value in health systems. Therefore the goal of this study is to determine the awareness and attitude of employees working for Deputy of Health of Isfahan University of Medical Science regarding telemedicine and its advantages. Method: This study uses a descriptive – analytical method with sectional information gathering. The investigated population consisted of all managers and experts employed by Deputy of health of Isfahan University of Medical Science. The sample size was determined based on inclusion criteria to be 60 people. The data gathering tool was a questionnaire designed by the researcher in order to determine the awareness and attitude of the subjects. In order to determine the validity and reliability of the questionnaire content validity method and Cronbach’s alpha were used. The information was analyzed using descriptive (frequency, average) and analytical (Spearman correlation test and independent t-test) statistics with the help of SPSS19 software. Findings: Research findings showed that the awareness and attitude of managers and experts toward telemedicine was mediocre. Spearman correlation test showed that there is a correlation between the educational degree and awareness of the subject, however the correlation coefficient was lower than 0.5 which shows a weak correlation (0.451). On the other hand, the calculated P-value of 0.008 showed that there is a meaningful relation between the education and awareness of managers regarding telemedicine. Conclusion: Due to importance of awareness and attitude in acceptance of new technologies, one can say that currently there is not enough readiness for planning and implementation of telemedicine projects in the Deputy of health. Therefore changes in the organizational culture, organizational structures and infrastructure, current plans and educating the employees in order to improve their awareness and attitude is of great importance.

      PubDate: Tue, 14 Apr 2015 02:53:20 GMT
       
  • Selective Inhibition on RAGE-binding AGEs Required by Bioactive Peptide
           Alpha-S2 Case in Protein from Goat Ethawah Breed Milk: Study of Biological
           Modeling

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Fatchiyah Fatchiyah, Ferlany Hardiyanti, Nashi Widodo.
      Background: Advanced Glycation End Products (AGE) play a pivotal role in the development various degenerative diseases such as diabetes, cardiovascular disease, stroke, neuropathy, and nephropathy. Different studies have been done to employ AGEs as drug targets for the diseases therapy. In previous study, we have found bioactive peptide from Ethawah goat milk for anti-diabetic that may work through inhibition of AGE receptor function. However, the mechanism of bioactive peptides inhibits AGE- AGE receptor (RAGE) bonding still not clear yet. Therefore we investigated the inhibition mechanism by calculate the potential energy binding among the peptides, AGEs and RAGE using molecular docking system. Methods: Modeling 3D-structure was predicted by SWISS-MODEL web server. The virtual interaction was analyzed by docking system using HEX 8.0, Pymol and Discovery Studio 4.0 software. Results: this study showed that AGEs (Argypirimidine, Imidazole, Pentosidine and Pyrraline) bind to C-domain of RAGE. The total energy binding of RAGE with Argypirimidine, Imidazole, Pentosidine and Pyrraline were 378.35kJ/mol, -74.57kJ/mol, -301.25kJ/mol and -400.72kJ/mol, respectively. We have found three peptides among eight peptides from Ethawah goat milk, which are able bind to C-domain of RAGE, there are CSN1S2 f41-47, CSN1S2 f182-189, and CSN1S2 f214-221. The CSN1S22 f41-47 at arginine residue 47 interacts with proline162, leusine163 and leusine158 of RAGE. The total binding energy between CSN1S2 f41-47, CSN1S2 f182-189, and CSN1S2 f214-221 with RAGE were -378.35 kJ/mol, -359.97kJ/mol, -356.78 kJ/mol, respectively. Total binding energy and binding pattern indicated that RAGE more prefer bind with peptide and block AGE bind to functional site of RAGE. Further analysis showed that complex peptide-RAGE shifted binding site of AGE on function domain RAGE. Conclusion: This study suggested that the peptides from Ethawah goat milk may act as an inhibitor of AGEs-RAGE interaction that impaired signal transduction cascade at the cellular level.

      PubDate: Tue, 14 Apr 2015 02:51:14 GMT
       
  • Comparison of Specific Ovarian Tumor Markers by Elecsys Analyzer 2010

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Lejla Hasanbegovic, Selma Alicelebic, Nedeljka Sljivo.
      Background: the most widely used tumor marker in ovarian cancer, often considered the ‘gold standard’ is CA125 but reliable clinical evidence demonstrates that human epididymis protein (HE4), used alone or in combination with CA125, substantially improves the accuracy of screening and/or disease monitoring. Aim: to evaluate the reliability of the determination a tumor marker HE4 in comparison with CA125 on the Elecsys analyzer 2010 in epithelial ovarian cancer, benign ovarian cyst and healthy controls. Methods: we prospectively determined CA125 and HE4 serum levels in the Biochemical-Immunological-Haematological “Medical Laboratory” Ilidza, Sarajevo, B&H between June 1st and December 31st 2011. Electro-chemiluminescence immunoassay (ECLIA) methods for quantitative determination in vitro were performed on the Roche/Hitachi Elecsys 2010 Immunoassay Analyzer. Standard methods of descriptive statistics were performed for the data analysis. Results: univariate statistical analyze of tumor marker control serum revealed a high reliability for both CA125 and HE4 determination (p>0.05). Levey-Jennings charts of quality control data show that the target and the obtained values of both markers control sera do not differ significantly in relation to the ideal value. In a total number of 60 patients compared values of tumor markers show a high correlation (r=0.85). This study confirmed higher sensitivity and specificity of HE4 tumor marker compared with CA125. ROC-AUC values show that the diagnostic performance of HE4 was significantly higher compared with CA125. Conclusion: We concluded that HE4 was better than CA125 as a single tumor marker.

      PubDate: Tue, 14 Apr 2015 02:49:19 GMT
       
  • The Ocular Trauma Score as a Method for the Prognostic Assessment of
           Visual Acuity in Patients with Close Eye Injuries

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Raif Serdarevic.
      Introduction: Traumatic injuries of the eye are the most common cause of loss of visual function. In our study we performed Ocula Trauma Score (OTS). We compared with the values of visual acuity of injury and thus get an accurate model for determining the prognostic value of the final visual acuity before treatment of the patient. This model is a reliable test for both the ophthalmologist and the patient. Aim of study: The aim of this study was to show the socioepidemiological and demographic profile, as well as the most common mechanism in ophthalmic injuries, so to determine the final visual acuity and assessment and evaluation of sensitivity and specificity of ocular trauma score (OTS), and most importantly to determine the prognostic value final visual acuity after eye injuries. Material and Method: We conducted a clinical-epidemiological, retrospective-prospective study at the Department of Ophthalmology, Clinical Centre University in Sarajevo in the period 2009-2011. A sample of 124 patients with diagnosed closed of eye injuries were recruited. We applied Classifying Closed Globe Injury, performed Calculating the OTS and convert of total raw points into % chance of vision outcomes. Results: Comparison of age groups by gender shows that there is no statistically significant (x2 = 5.155; p = 0.2718). Of the total number of closed eye injuries (N = 124) at the admission from groups D and E with the worst vision were 29 patients (23.38%), in group C had low visual acuity of 20 (16.12%), in group B the mean visual acuity 33 (26.61%), and in group A well-preserved visual acuity 42 (33.87%) patients. On the demission patients with well-preserved visual function was 84 (67.74%), with a medium of visual function 10 (80.64%), while the poorer visual function was 4 (3.225%) and 7 (5.645%) patients had a sense of light and projections and 1 (0.8%) patient had lost visual acuity-amaurosis. 18 (14:51%) patients did not take their eyesight due to a fresh post-operative recovery. Conclusion: Data on each patient are based on the possibility of such characteristics of the mechanism of injuries presentation of vision at the beginning of disease, injury and zones relative afferent pupillary defect possibility assumptions what will be with the vision postoperatively.

      PubDate: Tue, 14 Apr 2015 02:47:57 GMT
       
  • Design and Implementation of a Software for Teaching Health Related Topics
           to Deaf Students: the First Experience in Iran

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Maryam Ahmadi, Masoomeh Abbasi, Kambiz Bahaadinbeigy.
      Introduction: Deaf are not able to communicate with other community members due to hearing impaired . Providing health care for deaf is more complex because of their communication problems. Multimedia tools can provide multiple tangible concepts (movie, subtitles, and sign language) for the deaf and hard of hearing. In this study, identify the priority health needs of deaf students in primary schools and health education software has been created. Method: Priority health needs and software requirements were identified through interviews with teachers in primary schools in Tehran. After training videos recorded, videos edited and the required software has been created in stages. Results: As a result, health care needs, including: health, dental, ear, nails, and hair care aids, washing hands and face, the corners of the bathroom. Expected Features of the software was including the use of sign language, lip reading, pictures, animations and simple and short subtitles. Discussion: Based on the results of interviews and interest of educators and students to using of educational software for deaf health problems, we can use this software to help Teachers and student’s families to education and promotion the health of deaf students for learn effectively.

      PubDate: Tue, 14 Apr 2015 02:46:48 GMT
       
  • Ultrasound in Detection of Developmental Hip Dysplasia in Premature Born
           Children

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Verica Misanovic, Selma Dizdar, Fedzat Jonuzi, Hajra Maksic-Kovacevic, Selma Rahmanovic.
      Introduction: Developmental hip dysplasia represents the most common deformation of locomotor system in children. Developmental modulation of the hip is expressed during first year of life which is important for early diagnosis and treatment. Therefore, in the practice, it is very important to set a diagnosis early with application of simple and convenient methods (ultrasound) in order to achieve fast and efficient therapeutical effect and avoid permanent disability. Aim: The aim of this paper is to point out the increase of prematurely born infants and their survival thanks to the development of Unit for Intensive Neonatal Care at the Pediatric Clinics in Sarajevo. Material and methods: Clinical investigation included 150 infants (77 girls and 73 boys) in whom the developmental hip dysplasia was diagnosed with clinical exam, ultrasound exam and x-ray of the hips. The exams were done in period of January 2012 to August 2014 Results: Two groups of patients were formed. The first one consisted of premature infants, total number of 75 (34 girls and 41 boys), with developmental hip dysplasia that was diagnosed at the first exam at the Ultrasound unit of the Pediatric clinics and at the Intensive Neonatal Care Unit of the Pediatric Clinics in Sarajevo. Second (control) group consistsed of patients-on term infants who had diagnosed one of developmental hip dysplasia, total of 75 (43 girls and 32 boys) during first exam in the Ultrasound unit of the Pediatric clinics in Sarajevo. Conclusion: The frequency of premature birth is between 5 and 10% of all labors and demonstrates increasing trend. We suggest ultrasound examination of hips in each newborn, term or premature, at the age of 6 weeks after birth.

      PubDate: Tue, 14 Apr 2015 02:45:00 GMT
       
  • Combined Use of Cytogenetic and Molecular Methods in Prenatal Diagnostics
           of Chromosomal Abnormalities

    • Abstract: 2015-04-14T04-32-20Z
      Source: Acta Informatica Medica
      Meliha Stomornjak-Vukadin, Ilvana Kurtovic-Basic, Lejla Mehinovic, Rijad Konjhodzic.
      Aim: The aim of prenatal diagnostics is to provide information of the genetic abnormalities of the fetus early enough for the termination of pregnancy to be possible. Chromosomal abnormalities can be detected in an unborn child through the use of cytogenetic, molecular- cytogenetic and molecular methods. In between them, central spot is still occupied by cytogenetic methods. In cases where use of such methods is not informative enough, one or more molecular cytogenetic methods can be used for further clarification. Combined use of the mentioned methods improves the quality of the final findings in the diagnostics of chromosomal abnormalities, with classical cytogenetic methods still occupying the central spot. Material and methods: Conducted research represent retrospective-prospective study of a four year period, from 2008 through 2011. In the period stated, 1319 karyotyping from amniotic fluid were conducted, along with 146 FISH analysis. Results: Karyotyping had detected 20 numerical and 18 structural aberrations in that period. Most common observed numerical aberration were Down syndrome (75%), Klinefelter syndrome (10%), Edwards syndrome, double Y syndrome and triploidy (5% each). Within observed structural aberrations more common were balanced chromosomal aberrations then non balanced ones. Most common balanced structural aberrations were as follows: reciprocal translocations (60%), Robertson translocations (13.3%), chromosomal inversions, duplications and balanced de novo chromosomal rearrangements (6.6% each). Conclusion: With non- balanced aberrations observed in the samples of amniotic fluid, non- balanced translocations, deletions and derived chromosomes were equally represented. Number of detected aneuploidies with FISH, prior to obtaining results with karyotyping, were 6.

      PubDate: Tue, 14 Apr 2015 02:43:14 GMT
       
  • The Most Influential Scientists in the Development of Medical Informatics
           (4): Allan Cormack

    • Abstract: 2015-02-23T09-31-19Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Sun, 22 Feb 2015 10:13:10 GMT
       
  • Early Prenatal Diagnosis of Thoracopagus Twins by Ultrasound

    • Abstract: 2015-02-23T09-31-19Z
      Source: Acta Informatica Medica
      Mahmoud Alkhateeb, Mahmoud Mashaqbeh, Sami Magableh, Rafiq Hadad, Quteiba Nseer, Abdelkhaleg Alshboul.
      Introduction: Conjoined twins are identical twins joined in utero. It’s a rare phenomenon and present a unique challenge to obstetricians and pediatric surgeons. Conjoined twins are complex complication of monozygotic twinning, which is associated with high perinatal mortality. Case report: At our clinic complete anomaly scan was done, the patients was found to have monozygotic twins of 15 weeks gestation and carrying a conjoint twin. Our ultrasound revealed fully developed heads facing each other, joint at the thorax and sharing a common abdomen. These twins share a single heart with two atrium and two ventricle. They decide for termination of pregnancy after taken the opinion of religious people. Termination of pregnancy was performed by many methods and we chose to use cytotec tablets which inserted vaginally and the outcome was conjoint twin with two bodies fused from the upper thorax to lower belly. Both fetuses are female and died immediately after termination of pregnancy.

      PubDate: Sun, 22 Feb 2015 10:12:12 GMT
       
  • Value Innovation in Hospital: Increase Organizational IQ by Managing
           Intellectual Capitals

    • Abstract: 2015-02-23T09-31-19Z
      Source: Acta Informatica Medica
      Mahtab Karami, Mashallah Torabi.
      Hospital is a complex organization rich in intellectual capitals. Effective management of these assets in line with innovating value to reach strategic goals and objectives can lead to increasing organizational IQ. In hospital with high organizational IQ, Increasing syntropy in intellectual capitals can convert it to an agile, learner, innovative, and smart organization.

      PubDate: Sun, 22 Feb 2015 10:10:09 GMT
       
  • Predictors of Patients’ Satisfaction with Health Care Services in
           Three Balkan Countries (Macedonia, Bulgaria and Serbia): a Cross Country
           Survey

    • Abstract: 2015-02-23T09-31-19Z
      Source: Acta Informatica Medica
      Vladimir Lazarevik, Blasko Kasapinov.
      Background: Patients’ satisfaction with provided healthcare services is one of the factors to measure the overall quality of the delivered health care. Main objective of our study was to determine the common predictors associated with patients ‘satisfaction in three Balkan countries. Methods: We conducted web based survey among population in Macedonia, Serbia and Bulgaria using paid campaign over the social network Facebook. A questionnaire consisted of 31 questions was developed following studies on patients’ satisfaction conducted elsewhere. Descriptive analysis was performed to assess the predictors associated with patients’ satisfaction. In addition we performed content analysis to all open-ended responses. Results and discussion: In total 4118 respondents participated in the survey. Main predictors associated with low users satisfaction with the health care services in three surveyed countries are waiting time to appointments, huge administrative procedures, and attitudes of the medical personnel towards the patients. The analysis showed that there are many similarities in user experiences in three countries, but also there are some differences. Conclusions: The health care systems in these three counties are organized around centralized and monopolistic position of one health insurance fund that serves as main purchaser of health care services. Top three indicators of patients’ satisfaction across three countries are trust and overall satisfaction with the attention of the doctors, as well as satisfaction with the outcome of the treatment. Long waiting time and huge administrative procedures are determined as common predictor for lower patients’ satisfaction across these Balkan countries. Patients’ privacy protection is issue for concern in all three countries.

      PubDate: Sun, 22 Feb 2015 10:07:59 GMT
       
 
 
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