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Acta Informatica Medica    Follow    
  This is an Open Access Journal Open Access journal
     ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
     Published by ScopeMed Homepage  [75 journals]   [H-I: 2]
  • My View on Plagiarism
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Ermin Begovic.


      PubDate: Mon, 17 Mar 2014 12:33:11 GMT
       
  • Spinal Dissemination of Intracranial Glioblastoma in Bevacizumab Era: a
           Potential Bevacizumab-induced Mechanism
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Gentian Kaloshi, Arben Roji, Arsen Seferi, Bujar Cakani, Teona Bushati, Ermir Roci, Mentor Petrela.
      Spinal metastasis, a devastating neurologic complication of intracranial glioblastomas is not as uncommon as initially thought. It varies from 25% in supratentorial glioblastomas to 60% in infratentorial glioblastomas. The underlying pathogenesis spinal spread of high-grade gliomas is still unclear. To date, no causal responsibility of Bevacizumab (BEV) was noted. Here, we report for the first time, a case of thoracic intramedullary metastases from a cerebral glioblastoma pre-treated with BEV. A critical and exhaustive review is provided.

      PubDate: Mon, 17 Mar 2014 12:30:04 GMT
       
  • Use of the Toric Intraocular Lens for Keratoconus Treatment
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jasmin Zvornicanin, Emir Cabric, Vahid Jusufovic, Zlatko Musanovic, Edita Zvornicanin.
      A 50 year old man presented to Eye clinic University clinical centre Tuzla with bilateral visual impairment. Clinical examination revealed low visual acuity and keratoconus in both eyes, white cataract in right eye and diabetic retinopathy in left eye. Ultrasonography examination was normal. The patient underwent Trypan blue capsule staining, phacoemulsification and implantation of intraocular lens Alcon AcrySof SN60T9 16 D spherical and 6.0 D cylinder power. Phacoemulsification went uneventful and early postoperative recovery was successful. Visual acuity improved to 0,8 and fundus examination revealed background diabetic retinopathy. Postoperative follow up two years after surgery showed no signs of keratoconus progression and visual acuity maintained the same.

      PubDate: Mon, 17 Mar 2014 12:27:41 GMT
       
  • A Roadmap to Pre-Implementation of Electronic Health Record: the Key Step
           to Success
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Marjan Ghazisaeidi, Maryam Ahmadi, Farahnaz Sadoughi, Reza Safdari.
      Introduction: Initial attempts are made to implement electronic health record (EHR) in Iran, the present study aim is developing a proper roadmap to EHR in pre-implementation phase by expert views on the matter. Method: An initial framework was developed for pre- implementation based on reviewing literature on EHR implementation and descriptive-comparative with qualitative approaches in five countries. A questionnaire was designed in several sections using 47 main topics associated with pre-implementation. Cronbach’s alpha 0.89 confirmed the reliability of the data. Expert views were used to score each topic based on Likert scale and opinions were collected through Delphi. Then results analyzed using descriptive statistical analysis method. Result: Framework of EHR pre-implementation roadmap was presented in four phases: preliminaries, assessment, planning, and method of choosing system vendors. Priorities in each part were determined and reflected in the roadmap using expert views, analyses, and requirements of each phase. It seems strategic planning at different levels; assessment of needs; providing and managing financial resources, setting standards; examining the existing condition was determined as highest priorities in above phases. Conclusion: For successful implementation, developing national carefully-designed and well-documented EHR pre-implementing roadmap, Based on country situation, from strategic to operation level is necessary.

      PubDate: Mon, 17 Mar 2014 12:25:11 GMT
       
  • Cervical Length Measured by Transvaginal Ultrasonography and
           Cervicovaginal Infection as Predictor of Preterm Birth Risk
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Arnela Ceric Banicevic, Miroslav Popovic, Amela Ceric.
      Introduction: The study shows possibilities of transvaginal sonographic measurement of the cervix in prediction of premature birth risk. Goals: The aim of the study was to follow up the cervical length in the pregnant from 16th to 37th week, as well as to do a microbiological analysis of the vaginal and cervical flora and to identify relation between the cervical shortening and microbiological flora as well as with a premature birth. Material and methods: The investigation was conducted as a prospective study on two groups of female patients in Clinical Centre of Banja Luka. In the high risk group we had 8% of patients with cervical length bellow than 15mm, 30% of patients with cervical length from 15 to 25m and 62% of patients with cervical length bigger than 25mm. In the low risk group we had no patients with cervical length bellow 15mm, 95% of patients had cervical length bigger than 25mm and 5% of patients had cervical length from 15 do 25mm. Results: The regression coefficient of the cervical length in the high risk group was 0.44mm, while in the low risk group it was 0.26mm. In the high risk group 67.56% patients had a positive cervical smear finding, while in the low risk group it was 4%. A high premature birth (defined as birth before 36.6 weeks) incidence of 50% was presented in patients with cervical length bellow 15mm. In the group of patients with cervical length up to 25mm the premature risk incidence was 10.52±0.05. In the high risk group of patients with a positive cervical smear finding, regarding the cervical length the percentage was as follows; in the subgroup of 15mm length 88,89±11,87, in subgroup from 15 to 25mm was 62,07±11,43 and in the subgroup bigger than 25mm, 60.06±8.05. Conclusion: By the analysis of the first and second goal of our study we can conclude that ultrasound assessment of cervical length is simple and feasible in the 16th week of pregnancy in both groups, with high and low risk. The length of the cervix in this period is shorter in the high risk group compared with the low-risk group. This difference was not statistically significant, however, it clearly demonstrated connection between shorten length of the cervix with the preterm birth. A regression analysis shows that the shortening of the cervix length is more frequent in high risk group which is to be expected, bearing in mind that in this group, the risk of preterm delivery was significantly higher.

      PubDate: Mon, 17 Mar 2014 12:22:17 GMT
       
  • Experiences of Academic Members About their Professional Challenges: a
           Content Analysis Qualitative Study
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zohreh Shahhosseini, Mahmonier Danesh.
      Background: University faculty members of different disciplines in any country, by giving better quality services, will further accelerate the development of their respective countries. This study aims to explore the experiences of faculty members about their professional challenges. Aim: In this qualitative study, which was conducted in 2013, fifteen faculty members in the departments of clinical and basic sciences of Mazandaran university of Medical Sciences in northern Iran were chosen for semi-structured in-depth interviews by purposive sampling method. All tape-recorded data were fully transcribed and content analysis was performed. Results: After immersion and data analysis, three main themes were emerged including: “Imbalances in academic members’ tasks in different areas”, “Weakness of evaluation and promotion system” and “Failure to provide the infrastructure educational facilities”. The main themes and sub-themes are explained by the help of participants’ direct quotations. Conclusions: This study suggested that it is better to take effective measures to improve the faculty members’ situation and therefore increase their efficiency, effectiveness and productivity.

      PubDate: Mon, 17 Mar 2014 12:20:49 GMT
       
  • Proposed Use of the Computer as a Tool to Aid Analysis of Properties of
           Materials in Fixators of Spine
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Antonio Santos, Fernando Moreira.
      With objective of analyzing the mechanical behavior of the internal fixators of spine and of the bony structure, the pieces and the group were made (it structures bony x internal fixator) with the aid a software of solid modeling. The materials used in the rehearsals had been the titanium, now in the market and a castor oil polyurethane destined to the development of you implant bony.

      PubDate: Mon, 17 Mar 2014 12:16:37 GMT
       
  • A Comparative Study of the Proposed Models for the Components of the
           National Health Information System
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Maryam Ahmadi, Shahla Damanabi, Farahnaz Sadoughi.
      Introduction: National Health Information System plays an important role in ensuring timely and reliable access to Health information, which is essential for strategic and operational decisions that improve health, quality and effectiveness of health care. In other words, using the National Health information system you can improve the quality of health data, information and knowledge used to support decision making at all levels and areas of the health sector. Since full identification of the components of this system – for better planning and management influential factors of performance- seems necessary, therefore, in this study different attitudes towards components of this system are explored comparatively. Methods: This is a descriptive and comparative kind of study. The society includes printed and electronic documents containing components of the national health information system in three parts: input, process and output. In this context, search for information using library resources and internet search were conducted, and data analysis was expressed using comparative tables and qualitative data. Results: The findings showed that there are three different perspectives presenting the components of national health information system - Lippeveld and Sauerborn and Bodart model in 2000, Health Metrics Network (HMN) model from World Health Organization in 2008, and Gattini’s 2009 model. All three models outlined above in the input (resources and structure) require components of management and leadership, planning and design programs, supply of staff, software and hardware facilities and equipment. Plus, in the ‘’process’’ section from three models, we pointed up the actions ensuring the quality of health information system, and in output section, except for Lippeveld Model, two other models consider information products and use and distribution of information as components of the national health information system. Conclusion: the results showed that all the three models have had a brief discussion about the components of health information in input section. But Lippeveld model has overlooked the components of national health information in process and output sections. Therefore, it seems that the health measurement model of network has a comprehensive presentation for the components of health system in all three sections-input, process and output.

      PubDate: Mon, 17 Mar 2014 12:15:21 GMT
       
  • Reliability Assessment of Arthroscopic Findings Versus MRI in ACL Injuries
           of the Knee
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hristijan Kostov, Stojmenski Slavcho, Elena Kostova.
      Introduction: This study was conducted to analyze the reliability of clinical diagnosis in ACL tear injuries. Material and methods: All patients attending our clinic with knee pain from 2009 to 2013 underwent systematic and thorough clinical assessment. From one hundred and three patients with knee problems in 73 were arhroscopicaly diagnosed ACL tears. All these patients underwent therapeutic arthroscopic knee surgery. The clinical diagnosis was confirmed during this procedure. The accuracy, sensitivity and specificity were calculated based on these arthroscopic findings. Results: The accuracy of clinical diagnosis in our study was 82.5% for ACL tears. Our study revealed high sensitivity and specificity and almost high accuracy for ACL injuries of knee joint in comparison to arthroscopy. MRI is an appropriate screening tool for therapeutic arthroscopy, making diagnostic arthroscopy unnecessary in most patients. Conclusion: Magnetic resonance imaging is accurate and non invasive modality for the assessment of ligamentous injuries. It can be used as a first line investigation in patients with soft tissue trauma to knee.

      PubDate: Mon, 17 Mar 2014 12:13:55 GMT
       
  • Response of the Adrenergic System After Provoked Bronchoconstriction in
           Patients with Bronchial Asthma
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hilmi Islami, Ali Ilazi, Nijazi Gashi, Lirim Mustafa, Halit Maloku, Adelina Jashanica.
      Objective: In this paper, effect of the Tolazoline as antagonist of the alpha-2 adrenergic receptors in patients with bronchial asthma and chronic obstructive bronchitis was studied, and also the effect of stimulation with Hexoprenaline of beta-2 adrenergic receptor after bronchi-constriction caused with Propranolol, and Acetylcholine. Methods: Lung function parameters are determined with Body plethysmography. In patients with bronchial asthma and chronic obstructive bronchitis was registered resistance (Raw), was determined the amount of intrathoracic gas volume (ITGV), and specific resistance was calculated as well (SRaw). Aerosolization was done with standard aerosolizing machine–Asema. Results: The study included a total of 21 patients. Two hours after the inhalation of Propranolol, in experimental group, it was applied the blocker of alpha-2 adrenergic receptors (Tolazoline 20 mg / ml with inhalator ways), which did not cause changes in bronchomotor tonus of tracheobronchial system (p> 1.0). Meanwhile, at the same patient, stimulation of beta-2 adrenergic receptor with Hexoprenaline (2 inh x 0.2 mg) is associated with a significant decrease of the specific resistance of airways (SRaw, p < 0.01). Control group results show that after bronchi-constriction caused by Propranolol–aerosol (20 mg / ml) in patients with bronchial asthma and chronic obstructive bronchitis, an increase of specific resistance in airways was caused (SRaw, p < 0.01), which confirms the presence of hyper-reactive bronco-constrictor effects intermediated by vagal ways. Two hours after Propranolol, inhaled Hexorenaline has blocked the action of Propranolol, but not entirely. Furthermore, two hours after acetylcholine-aerosol (1 mg /ml) was applied, inhaled Ipratropium (2 inh x 1 mg) has fully blocked the action of chemical bronchoconstrictor mediators, causing a decline of specific resistance in the airways (SRaw; p < 0.01). Conclusion: This suggests that primary mechanism, which would cause reaction in patients with increased bronchial reactibility, is prevalence of the cholinergic system over adrenergic one, and not the relationship in between alpha-2 and beta-2 adrenergic receptors.

      PubDate: Mon, 17 Mar 2014 12:11:57 GMT
       
  • Comparison Between Impact Factor, Eigenfactor Metrics, and SCimago Journal
           Rank Indicator of Pediatric Neurology Journals
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hamidreza Kianifar, Ramin Sadeghi, Leili Zarifmahmoudi.
      Background: Impact Factor (IF) as a major journal quality indicator has a series of shortcomings including effect of self-citation, review articles, total number of articles, etc. In this study, we compared 4 journals quality indices ((IF), Eigenfactor Score (ES), Article Influence Score (AIS) and SCImago Journal Rank indicator (SJR)) in the specific Pediatric Neurology journals. Methods: All ISI and Scopus indexed specific Pediatric Neurology journals were compared regarding their 2011 IF, ES, AIS and SJR. Results: Fourteen pediatric Neurology journals were identified, 3 of which were only Scopus indexed and the others were both ISI and Scopus indexed. High correlation was found between IF and AIS (0.850). Correlations between IF and other indices were not that high. Self-citation, total article number and review articles were related to the IF and other indices as well as their ranks. English language and citation to non citable item didn’t have any effect on pediatric neurology journals ranks. Conclusion: Although all the above mentioned indicators can be used interchangeably, using all considered indices is a more appropriate way than using only IF for quality assessment of pediatric neurology journals.

      PubDate: Mon, 17 Mar 2014 12:10:05 GMT
       
  • Conceptual Model of Clinical Governance Information System for Statistical
           Indicators by Using UML in Two Sample Hospitals
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Fatemeh Rangraz Jeddi, Mehrdad Farzandipoor, Masoud Arabfard, Azam Haj Mohammad Hosseini.
      Objective: The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. Background: However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. Material and Methods: A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. Results: With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital’s clinical governance was required to create a database. Conclusion: Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems.

      PubDate: Mon, 17 Mar 2014 12:07:44 GMT
       
  • An Experimental Comparison of Two Different Technetium Source Activities
           Which Can Imitate Thyroid Scintigraphy in Case of Thyroid Toxic Nodule
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Ramë Miftari, Ferki Fejza, Xhavit Bicaj, Adem Nura, Valdete Topciu, Ismet Bajrami.
      Purpose: In cases of thyroid toxic autonomous nodule, anterior projection of Tc-99m pertechnetate image shows a hot nodule that occupies most, or the entire thyroid lobe with near-total or total suppression of the contra lateral lobe. In this case is very difficult to distinguish toxic nodule from lobe agenesis. Our interest was to estimate and determinate the rate of radioactivity when the source with high activity can make total suppression of the second source with low activity in same conditions with thyroid scintigraphy procedures. Material and methodology: Thyroid scintigraphy was performed with Technetium 99 meta stable pertechnetate. A parallel high resolution low energy collimator was used as an energy setting of 140 KeV photo peak for T-99m. Images are acquired at 200 Kilo Counts in the anterior projection with the collimator positioned as close as the patient’s extended neck (approximately in distance of 18 cm). The scintigraphy of thyroid gland was performed 15 minutes after intravenous administration of 1.5 mCi Tc-99m pertechnetate. Technetium 99 meta stable radioactive sources with different activity were used for two scintigraphies studies, performed in same thyroid scintigraphy acquisition procedures. In the first study, were compared the standard source with high activity A=11.2 mCi with sources with variable activities B=1.33 mCi; 1.03 mCi; 0.7 mCi; 0.36 mCi; and 0.16mCi) in distance of 1.5cm from each other sources, which is approximately same with distance between two thyroid lobes. In the second study were compared the sources with low activity in proportion 70:1(source A = 1.5 mCi and source B=0.021mCi). As clinical studies we preferred two different patents with different thyroid disorders. There were one patient with thyroid toxic nodule in the right lobe, therefore the second patient was with left thyroid nodule agenesis. Results: During our examination, we accurately determined that two radioactive sources in proportion 70:1 will be displayed as only one source with complete suppression of other source with low radioactivity. Also we found that covering of toxic nodules with lead cover (plaque), can allow visualization of activity in suppressed lobe. Conclusion: Our study concluded that total lobe suppression, in cases of patients with thyroid toxic nodule, will happened for sure, if toxic nodule had accumulated seventy times more radioactivity than normal lobe. Also we concluded that covering of the toxic nodule with lead plaque, may permit the presentation of radioactivity in suppressed nodule.

      PubDate: Mon, 17 Mar 2014 12:05:48 GMT
       
  • Sensitivity of Symptomatology Versus Diagnostic Procedures and
           Concentration of CEA and CA19–9 in the Early Detection of Colorectal
           Cancer
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zora Vukobrat-Bijedic, Azra Husic-Selimovic, Nina Bijedic, Admir Mujkic, Amela Sofic, Bisera Gogov, Amila Mehmedovic, Ivana Bjelogrlic, Sanjin Glavas, Aleksandra Djuran.
      Introduction: Colorectal cancer is the major diagnostic and therapeutic problem. The number of patients in the world has increased recently. In our country it is detected late and patients visit doctor in the advanced stage of the disease with already developed metastases. Material and methods: A clinical study was conducted at the Clinic of gastroenterohepatologists, Clinical Center of Sarajevo University on 164 patients. Special attention was given to the symptoms, which are considered to be a macroscopically visible as bleeding, anemia pain, weight loss and disturbance of defecation. Smoking had no effect because a small number of observed patients smoked. Endoscopic examination revealed localization of the tumor in the colon and then underwent targeted biopsy, histological analysis by pathologist, and we determined the concentration of CEA and CA19-9 in the serum. Results: In order to get the most relevant results we used larger data set. The program used to prepare the data was Microsoft Excel 2013, and for the creation of decision trees is a used software RapidMiner version 5. Our research has shown that patients older than 55 years with significant stenosis, metastasis and diarrhea that lasted longer than 3.5 months and bleeding that lasted up to 10 months had cancer of the rectum. Bleeding that lasts longer than 10 months indicated that it was the case of cancer that was localized in the rectum in men and sigma in women. Patients older than 82.5 years and had diarrhea up to 3.5 months developed cancer in the sigma part of the colon. Analyzing pain as a symptom of an alarm, the study found that pain that lasts longer than a few days, is caused by rectal cancer, and occurs after the age of 70.5 years, and in patients younger than 63 years anemia as a alarm symptom, which lasted more than two months in men was caused by cancer of the rectum and in women cancer in other localizations within colon. In patients without stenosis developed bleeding as the most important symptom. We can say that after the age of 74 years cancer of the rectum and sigmoid is more common in men and in women dominate sigma and other locations in the colon. In patients under the 70 years of age with short time of bleeding, cancer predominates in rectum. In patients younger than 63 years can be concluded that weight loss is greater than 8 kg follows rectal cancer. In patients with bleeding that lasted one month or more as classifier occurring the age and gender. Patients younger than 74 years have rectal cancer, while older than 73 years have cancer at other sites. In women these locations are sigma and rectum. Conclusion: Based on this study we can conclude that regardless of the technical advances in medicine must pay special attention to the symptoms that doctors will refer to the localization of the tumor, stenosis of the intestine and possibly metastasis.

      PubDate: Mon, 17 Mar 2014 12:03:11 GMT
       
  • Use of Quantitative Fluorescent Polymerase Chain Reaction (QF PCR) in
           Prenatal Diagnostic of Fetal Aneuploidies in a 17 Month Period in Parallel
           with Karyotyping
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Rijad Konjhodzic, Edina Dervovic, Ilvana Kurtovic-Basic, Meliha Stomornjak-Vukadin, Adis Muhic, Sumeja Baljevic, Aida Pirnat-Gegic, Ejub Basic, Nurija Bilalovic.
      Introduction: QF PCR has recently entered diagnostic practice as a possible way to bypass culturing of the fetal cells, as well as to provide a rapid response following amniocentesis. Material and methods: The effective value of the QF PCR remains a much debated issue, positions ranging from that it makes classic kayotyping obsolete except in special occasions, to that it is no more than a guideline for a mandatory karyotype. Current practices of the gynecology specialists generates samples in such fashion that kariotyping of samples quickly falls behind to the point of obsoleteness, because, by the time a karyotype has been finished, a window of opportunity for termination of pregnancy has closed. Results: QF PCR provides a rapid response alternative, but it is necessary to establish its reproducibility, as well as an algorithm of its use along classic kariotyping. This study contains samples processed in a period from August 1, 2012 to December 31 2013 in both QF PCR and classic karyotype. Object of this study was compare results obtained by two methods, and establish confidence interval of the QF PCR testing. Overall, 661 amniotic fluid samples were processed and typed with QF PCR, out of which 221 were done in parallel with karyiotyping, as an confirmation of results.

      PubDate: Mon, 17 Mar 2014 11:59:48 GMT
       
  • Review of the Journal Acta Informatica Medica in 2013
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.


      PubDate: Mon, 17 Mar 2014 11:57:50 GMT
       
  • A Short Factography About IMIA and EFMI
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jacob Hofdijk, Patrick Weber, John Mantas, George Mihalas, Izet Masic.
      International Medical Informatics Association (IMIA) and European Federation of Medical Informatics are scientific associations which represents Health/Medical informatics as scientific and profesional disciplines. Those associations have long tradition in spreading knowledge, experiences and strategies in organization, practical applications and education within Health, Medical and Biomedical informatics in approximately 60 countries the world. In this review we present basic facts about IMIA and EFMI.who celebrate this 50 years of their establishing as professional associations.

      PubDate: Sat, 25 Jan 2014 11:25:07 GMT
       
  • The 50th Anniversary IMIA History of Medical Informatics Project
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Casimir A. Kulikowski.
      At the meeting of the IMIA Board in 2009 in Hiroshima, it approved an IMIA 50th Anniversary History Project to produce a historical volume and other materials to commemorate the anniversary of the foundation of the predecessor of IMIA–the IFIP-TC4 in 1967. A Taskforce was organized under the direction of Casimir Kulikowski, then the VP for Services of IMIA, and since that time it has met regularly to plan and implement the 50th Anniversary History of IMIA as an edited volume, and as material available online on a Media Presentation Database. The IMIA Taskforce is gathering IMIA-related archival materials, currently accessible through a prototype media repository at Rutgers University in order to help those contributing to the book or writing their own recollections and histories. The materials will support a chronicle of the development and evolution of IMIA, its contributors, its sponsored events and publications, educational and other professional activities. During 2013 Workshops were held at the Prague EFMI-STC meeting in April and at the MEDINFO 2013 Congress in Copenhagen in August.

      PubDate: Sat, 25 Jan 2014 11:16:52 GMT
       
  • A Short History of Medical Informatics in Bosnia and Herzegovina
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.
      The health informatics profession in Bosnia and Herzegovina has relatively long history. Thirty five years from the introduction of the first automatic manipulation of data, thirty years from the establishment of Society for Medical Informatics BiH, twenty years from the establishment of the Scientific journal „Acta Informatica Medica (Acta Inform Med“, indexed in PubMed, PubMed Central Scopus, Embase, etc.), twenty years on from the establishment of the first Cathedra for Medical Informatics on Biomedical Faculties in Bosnia and Herzegovina, ten years on from the introduction of the method of “Distance learning” in medical curriculum. The author of this article is eager to mark the importance of the above mentioned Anniversaries in the development of Health informatics in Bosnia and Herzegovina and have attempted, very briefly, to present the most significant events and persons with essential roles throughout this period.

      PubDate: Sat, 25 Jan 2014 11:15:29 GMT
       
  • Medical Informatics in Croatia – a Historical Survey
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Gjuro Dezelic, Josipa Kern, Mladen Petrovecki, Vesna Ilakovac, Mira Hercigonja-Szekeres.
      A historical survey of medical informatics (MI) in Croatia is presented from the beginnings in the late sixties of the 20th century to the present time. Described are MI projects, applications in clinical medicine and public health, start and development of MI research and education, beginnings of international cooperation, establishment of the Croatian Society for MI and its membership to EFMI and IMIA. The current status of computerization of the Croatian healthcare system is sketched as well as the present graduate and postgraduate study MI curricula. The information contained in the paper shows that MI in Croatia developed and still develops along with its advancement elsewhere..

      PubDate: Sat, 25 Jan 2014 11:13:38 GMT
       
  • Five Periods in Development of Medical Informatics
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.
      Medical informatics, as scientific discipline, has to do with all aspects of understanding and promoting the effective organization, analysis, management, and use of information in health care. While the field of Medical informatics shares the general scope of these interests with some other health care specialities and disciplines, Medical (Health) informatics has developed its own areas of emphasis and approaches that have set it apart from other disciplines and specialities. For the last fifties of 20th century and some more years of 21st century, Medical informatics had the five time periods of characteristic development. In this paper author shortly described main scientific innovations and inventors who created development of Medical informatics.

      PubDate: Sat, 25 Jan 2014 11:12:15 GMT
       
  • Evolution of Trends in European Medical Informatics
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      George I. Mihalas.
      This presentation attempts to analyze the trends in Medical Informatics along half a century, in the European socio-political and technological development context. Based on the major characteristics which seem dominant in some periods, a staging is proposed, with a description of each period – the context, major ideas, views and events. A summary of major features of each period is also added. This paper has an original presentation of the evolution of major trends in medical informatics.

      PubDate: Sat, 25 Jan 2014 11:10:41 GMT
       
  • An Abridged History of Medical Informatics Education in Europe
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Arie Hasman, John Mantas, Tatyana Zarubina.
      This contribution presents the development of medical informatics education in Europe. It does not discuss all developments that took place. Rather it discerns several themes that indicate the progress in the field, starting from the initiation phase to the final quality control phase. .

      PubDate: Sat, 25 Jan 2014 11:08:11 GMT
       
  • Reflections On the Development of Medical Informatics
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Barry Barber, Maureen Scholes.
      The recording of numbers appears to pre-date the emergence of writing and excavations of the clay tablets of civilisations in the Middle East have shown that clay tablets were used to keep account of activities undertaken in a systematic fashion. Correspondingly, various forms of abacus have been used types of calculation from the Sumerian abacus dating from about 4 ½ thousand years ago to the Chinese abacus (Suanpan) from around 2 thousand years ago. As time passed various forms of writing were developed using animal hides, which were developed as vellum and papyrus which eventually developed into paper. Wood block printing, also, was a very ancient art and movable type printing had been utilised in the far East but the development of movable type page setting in Europe transformed the process of printing.

      PubDate: Sat, 25 Jan 2014 11:03:18 GMT
       
  • The Early History of European Federation of Medical Informatics
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hans E. Peterson.
      The story of the European Federation of Medical Informatics (EFMI) can be looked upon as one of the followers from the early days of the development of Societies and federations for persons interested in Information Technology and in cooperation and exchange of information and technology, not only in countries but also between countries.

      PubDate: Sat, 25 Jan 2014 11:00:05 GMT
       
  • About the Beginnings of Medical Informatics in Europe
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Francis Roger France.
      The term “Informatics” was created in 1962 from two words, information and automatic, and covers all techniques, information concepts and applications of computers. Among them, medicine is the field where we will describe some factors of development in Europe since the late sixties. It took some time for obtaining the acceptance of this new terminology worldwide, but today medical informatics is a well defined discipline which had a tremendous development last decades. This paper tries to recall the context and events from the beginning of medical informatics in Europe.

      PubDate: Sat, 25 Jan 2014 10:57:33 GMT
       
  • History of Medical Informatics in Europe - a Short Review by Different
           Approach
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      George Mihalas, Jana Zvarova, Casimir Kulikowski, Marion Ball, Jan van Bemmel, Arie Hasman, Izet Masic, Diane Whitehouse, Barry Barber.
      The panel intended to collect data, opinions and views for a systematic and multiaxial approach for a comprehensive presentation of “History of Medical Informatics”, treating both general (global) characteristics, but emphasizing the particular features for Europe. The topic was not only a subject of large interest but also of great importance in preparing a detailed material for celebration of forty years of medical informatics in Europe. The panel comprised a list of topics, trying to cover all major aspects to be discussed. Proposals of staging the major periods of medical informatics history were also discussed.

      PubDate: Sat, 25 Jan 2014 10:56:16 GMT
       
  • Special Tribute on Morris F. Collen: Charismatic Leader of Medical
           Informatics
    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Marion Ball, Donald Lindberg, Izet Masic.
      This editorial is dedicated in honor of Morris F. Collen, MD, a pioneer in the field of medical informatics. During his remarkable career, Dr. Collen’s has made many important contributions not only to the field of medical informatics, but also to the public health and the creation of new models of payment and prevention. His endeavors and ideas found fertile ground and left a mark not only in the national, but also in the international setting.

      PubDate: Sat, 25 Jan 2014 10:54:36 GMT
       
  • As Well as Proper Citation, References in Biomedical Articles Should Be
           Accurate
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Robert Siebers.


      PubDate: Wed, 04 Dec 2013 10:34:24 GMT
       
  • Atrioventricular Septal Defect with Common Atrioventricular Junction
           Guarded by a Common Valve Consisting of Left Atrioventricular Trifoliate
           Valve
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Xhevdet Krasniqi, Masar Gashi, Blerim Berisha, Ejup Pllana, Aurora Bakalli, Flora Abazi, Dardan Koçinaj.
      Introduction. Atrioventricular septal defect with common atrioventricular junction is a rare adult congenital cardiac syndrome. This occurrence with prolonged survival is exceptionally rare. Case report. We present the case of a patient who presented with this defect with common atrioventricular junction who survived to the age of 32. We describe a 32-year-old man with atrioventricular septal defect with common atrioventricular junction guarded by a common valve. His history, clinical course, and anatomic findings are discussed along with the factors which may have contributed to his longevity, which is unique in the medical literature. His management reflected the state of medical knowledge at the time when he presented, and although alternate approaches may have been utilized if the patient presented today. We discuss the findings, frequency, classification, and management of congenital defects. Development of embryonic structure is altered by interaction between genetics and environmental factors toward a rare associated of congenital cardiac defects-complex congenital heart disease. Conclusion. This case demonstrates that patients with very complex congenital cardiac disease may survive to adulthood, presenting challenges in both medical and surgical treatment.

      PubDate: Wed, 04 Dec 2013 10:33:27 GMT
       
  • Open Data Sharing in the Context of Bioresources
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Paola DeCastro, Alessia Calzolari, Federica Napolitani, Anna Maria Rossi, Laurence Mabile, Anne Cambon-Thomsen, Elena Bravo.
      Recently many international initiatives have been developed to improve access to scientific information and to promote open data sharing. In the complex field of bioresources, the BRIF (Bioresource Research Impact Factor) project aims to create suitable methods to recognise and measure the use and impact of biological resources in scientific/academic work, in order to maximize access by researchers to collections of biological materials and attached databases, and to recognize efforts involved in their maintenance. The lack of a proper recognition of scientific contribution is in fact a major obstacle which impedes bioresource sharing. In this context, the BRIF initiative can be considered as a tool to facilitate research resource sharing,

      PubDate: Wed, 04 Dec 2013 10:17:19 GMT
       
  • Trends in Authorship in an Indian Pediatric Dentistry Journal: Relevance
           of Matthew Effect
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Jatinder Kaur Dhillon, Gauri Kalra, Ashutosh Sharma, Vijay Prakash Mathur.
      Introduction: The maxim “rich get richer and the poor get poorer” forms the basis for Matthew effect in Science. Our goal of conducting this study was to test the hypothesis that the gap in number of publications between renowned, older authors and newer authors amongst Indian pediatric dentists widens over time as stated by the Matthew effect and possible trends in publication in Journal of Indian Society of Pedodontics & Preventive Dentistry (JISPPD). Materials and methods: It was hypothesized that the Matthew effect is applicable to the work published by Indian Pedodontists in the official publication of Indian Society of Pedodontics & Preventive Dentistry (ISPPD). The names of the authors in JISPPD from 1996 to 2011 were recorded year wise and the data was entered in Microsoft excel 2007 and analyzed using SPSS software. Results: The study revealed that there were a total of 823 papers published in JISPPD during the study period (1996 to 2011) by 1142 authors. 71.6% authors had contributed only one paper and 14.4% authors had contributed two papers during the study period. Only 0.6% authors had contributed to 20 or more papers. The results revealed evidence of Matthew effect for publications in JISPPD and the effect is relatively large. Conclusions: The results of the study showed that the Matthew effect is prevalent in the publication trends in JISPPD.

      PubDate: Wed, 04 Dec 2013 10:15:36 GMT
       
  • Forearm Approach for Percutaneous Coronary Procedures
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Zoran Stajic, Radoslav Romanovic, Dragan Tavciovski.
      This article gives contemporary review on the forearm approach for percutaneous diagnostic and interventional coronary procedures. Advantages and disadvantages as well as practical issues and current controversies regarding both radial and ulnar artery approach are discussed throughout the paper. Having in mind advantages of forearm approach in terms of safety and comfort over the traditional femoral approach, as well as the rapid development of invasive technology in the past years, it will probably become the default vascular approach for all percutaneous coronary procedures in the near future.

      PubDate: Wed, 04 Dec 2013 10:13:05 GMT
       
  • Computerized Tomography of Thoracic Pathologies in the Pediatric Age
           Group: Pictorial Essay
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Aysegul Solmaz-Tuncer, Safiye Gurel, Kamil Gurel, Ahmet Ozbag, Ayten Pamukcu, Zeliha Cosgun.
      Aim of the study. The purpose of this study is to illustrate the imaging findings of the lung parenchyma and the thoracic wall pathologies in pediatric age group using Standard (CT) and High-Resolution Computed Tomography (HRCT). Results and discussion. We discuss and illustrate the following: Pleural hematoma, Pulmonary Contusion, Histiocytosis X, Tuberculosis, Right sided arcus aortae, Pectus excavatum, Operated Pectus excavatum, Morgagni hernia, Pleurisy, Right middle lobe syndrome, Pneumonia, Hydatid Cyst, Takayasu arteritis, Kartagener syndrome, Bronchiectasis, Bronchiolitis obliterans organizing pneumonia, and Osteomyelitis. We also discuss the diagnosis clues.

      PubDate: Wed, 04 Dec 2013 10:11:18 GMT
       
  • Assessment of Osteoporosis in Family Medicine Obtained by Ultrasound
           Densitometry
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Esad Alibasic, Enisa Ramic, Olivera Batic Mujanovic, Enes Avdibasic, Damir Husic, Alma Alic.
      Introduction: Osteoporosis is a disease characterized by a decrease in bone mineral density, making bones become less rigid, and therefore susceptible to fractures, either spontaneously or with force, which is lower than otherwise needed for healthy bones fractured. Nearly 10% of the world population and 30% of women after menopause, suffer from osteoporosis. Clinical assessment of osteoporosis in family medicine is key to prevention, early detection and treatment of osteoporosis. Objective: To investigate the possibility of early detection and diagnosis of osteoporosis by analyzing the risk factors for osteoporosis and to compare the results with the parameters obtained by ultrasound densitometry of calcaneus, and determine the relationship of calcaneus densitometry with DXA findings, as the gold standard for the diagnosis of osteoporosis. Patients and methods: The study included all patients of Family Medicine Kalesija Team 1, aged 50 years and over, a total of 711 patients, of whom 425 were women and 286 men. In all patients we assessed the existence of the following risk factors for osteoporosis: Constitutional: gender, age, weight, constitution, menarche and menopause, loss of height and stooped posture; Living habits: smoking, alcohol consumption, coffee, physical activity, and medications: long-term use corticosteroids, anticonvulsants, antacids, thyroid hormones. Comorbidity: history of fractures, hyperthyroidism, COPD, Chussing’s disease, diabetes. In the group of high-risk patients determined by the clinical assessment, quantitative ultrasound densitometry screening was carried out. Monitoring parameters derived with densitometry: the value of T-score, BUA (Broadband Ultrasound Attenuation), SOS (Speed ​​of Sound), QUI (Quantitative Ultrasound Index). To confirm the diagnosis of osteoporosis, in all patients with positive findings using ultrasound densitometry (T score lower than 2.5), another densitometry was performed by standard DXA method. Results: The incidence of osteoporosis was 96% in women and 4% in men. Differences in prevalence between men and women are statistically significant. People with and without osteoporosis significantly differ in gender, age, weight, constitution (BMI-Body Mass Index). The parameters that distinguish those with and without osteoporosis: age, weight, height, BMI, gender. Out of the total of 711 patients, in 11% of patients the clinical evaluation showed the existence of high risk of osteoporosis. In 9.8% patients, the values ​​were determined by ultrasound densitometry, where T score was lower than 2.5 what induces a high risk of fractures, and for 8.8% patients the DXA confirmed the diagnosis of osteoporosis. Conclusion: Clinical assessment of osteoporosis in the family medicine clinic performed in timely and focused history of risk factors for osteoporosis, with additional findings from quantitative densitometry of calcaneus, was sufficient for the early detection and screening of patients with high risk for osteoporosis. With good clinical assessment of osteoporosis it will be necessary to send all patients who enter the high-risk group to undergo ultrasound densitometry of calcaneus, to make it possible to determine the risk of bone fractures and osteoporosis in time, and then refer patients for further processing and DXA measurements according to the guidelines by the WHO.

      PubDate: Wed, 04 Dec 2013 10:01:43 GMT
       
  • Early Amniocentesis as a Method of Choice in Diagnosing Gynecological
           Diseases
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Sebija Izetbegovic, Senad Mehmedbasic.
      Introduction: The aim of prenatal diagnosis is to detect fetal structural and genetic abnormalities. Used are different medical methods, procedures, processes and techniques. For this reason we can speak about the prevention and detection of hereditary diseases and congenital anomalies in the unborn fetus. Material and methods: The authors analyzed the results of early amniocentesis tests performed during 2009 in Institute for Gynecology, Infertility and Perinatology “Mehmedbasic” in Sarajevo. Performed is 299 analysis of amniotic fluid after amnion puncture done in the Institute or at the Clinic of Gynecology and Obstetrics (GAK) Sarajevo. Results and Discussion: Indications for the performance of early amniocentesis were: age greater over 35 (84.9%), positive ultrasound markers (1.6%), positive biochemical markers (5.6%) and positive family history for hereditary diseases (7.9%). Detected was 19 pathological cariograms or very high 7% of the total annual number of amniocentesis. An analysis of the distribution of pregnant women in relation to the indication of the result of cytogenetic analysis for each table made ​​positive predictive value (PPV). For indicator age PPV was 0.11, 0.66 for ultrasound markers, for biochemical markers 0.13, for other indications–0.04. The logistic regression model (odds -ratio 11.234 ) indicate a positive ultrasound findings in relation to the year indicates that the risk to gain abnormal fetal karyotype 13 times higher when using only age as an indication for early amniocentesis. Of the 19 pathological cariogram largest number refers to M.Down (10), Sy. Edwards was detected in 2 patients, Sy. Klinefelter in 3, mosaicism in 3 and translocation gene in two of the fetus. Conclusion: The authors would like to acknowledge a very high percentage of pathological cariogram risk groups, the extension of indications for RAC indicate the value of ultrasound markers as a good screening methods and the need for social incentives to perform screening tests and early amniocentesis in B&H in order to prevent genetic abnormalities.

      PubDate: Wed, 04 Dec 2013 09:59:51 GMT
       
  • Activity of the Adrenergic Nerve System in the Airways Permeability of
           Healthy Persons
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Njazi Gashi, Pëllumb Islami, Lirim Mustafa, Halit Maloku, Arta Veseli, Hilmi Islami.
      Objective: In this work, role of the adrenergic nerve system (alpha1 and beta2) in adjustment of the bronchomotor tonus in healthy people was researched. Methods: Parameters of the lung function are determined by Body plethysmography. Raw and ITGV were registered and SRaw was calculated as well. Aerosolization is done with standard aerosolizing machines – Asema. Results: Results gained shows that following the blockade of beta-2 adrenergic receptor with Propranolol (20 mg–aerosol), stimulation of alpha adrenergic receptor with Oxedrine (120 mg-aerosol) and blockage of these receptors with Tolazoline (20 mg-aerosol), does not change significantly the bronchomotor tonus of the tracheobronchial tree (p> 0.1). Meanwhile, stimulation of the beta-2 adrenergic receptor with Hexoprenaline (2 inh x 0.2 mg) is associated with a significant increase of the peripheral resistance of the airways (p < 0.01). Conclusion: This suggests that the activity of the alpha1-adrenergic receptor, unlike the activity of the beta2-adrenergic receptor in the healthy people smooth musculature, is not significant and as such is insufficient to oppose to the tonic activities of the cholinergic system.

      PubDate: Wed, 04 Dec 2013 09:57:54 GMT
       
  • Strategies for Improving the Data Quality in National Hospital Discharge
           Data System: a Delphi Study
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Farahnaz Sadoughi, Zahra Mahmoudzadeh-Sagheb, Maryam Ahmadi.
      Introduction: National hospital discharge data system can play a critical role in community health assessment, disease surveillance, strategic planning, policymaking, service quality control, and research. Moreover, the quality of hospital discharge data affects the usefulness of the data and is one of the prerequisites for effective utilization of the data. Thus, the present study aimed to identify the necessary actions for improving the data quality in the national hospital discharge data system and present a model for Iran based on the experiences of England, Canada, and New Zealand. Methods: In doing so, the measures performed in these countries were investigated. The related data were organized in six categories of standards and procedures, training and coordination with the users, assurance from the capability of the system’s software, data modification, data quality control, and documentation and reporting the data quality. According to the gathered data, the primary model was designed. Then, the model was assessed using a two-round Delphi technique by 33 and 31 experts, respectively. Conclusion: According to the findings, a model was presented in order to improve the data quality of Iran’s national hospital discharge data system.

      PubDate: Wed, 04 Dec 2013 09:56:26 GMT
       
  • Which Pharmaceutical Sales Representatives’ Features do Slovenian
           Family Physicians Value'
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Zalika Klemenc-Ketis, Janko Kersnik.
      Introduction: One of the key strategies for marketing new drugs to physicians is personal selling by pharmaceutical sales representatives (PSRs). Goal: The aim of this study was to determine which features of PSR’s are most valued by Slovenian family physicians (FPs). Methods: We performed a cross-sectional observational postal survey in FPs. We sent the invitation for cooperation in the study to all Slovenian FPs working in family practices at the primary level of care (N = 895). Data was collected using a validated PSRs’ assessment scale. It consists of 12 questions on PSRs’ assessment that could be answered on a seven-point Likert scale. Results: The response rate was 27.6%. There were 174 (70.4%) of female physicians among the respondents. Average age of the respondents was 48.3 ± 9.0 years. Highly assessed PSRs’ characteristics were “Provides objective product information”, “Does not mislead”, and “Shows good knowledge on the subject promoted”. Worst rated PSRs’ characteristics were “Possesses knowledge on health care system”, “Same person for the product of company for a longer period of time”, and “Acts friendly”. Conclusions: Slovenian FPs value PSRs’ selling and communication skills and trustworthiness highly. FPs and PSRs develop a personal relationship which reflects in different perceptions of various PSRs’ characteristics by FPs.

      PubDate: Wed, 04 Dec 2013 09:55:27 GMT
       
  • Discharge Against Medical Advice in the Pediatric Wards in Boo-ali Sina
           Hospital, Sari, Iran 2010
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Benyamin Mohseni Saravi, Esmaeil Reza Zadeh, Hasan Siamian, Mahboobeh Yahghoobian.
      Introduction: Since children neither comprehended nor contribute to the decision, discharge against medical advice is a challenge of health care systems in the world. Therefore, the current study was designed to determine the rate and causes of discharge against medical advice. Methods: This descriptive cross-sectional study was done by reviewing the medical records by census method. Data was analyzed using SPSS software and x2 statistics was used to determine the relationship between variables. The value of P

      PubDate: Wed, 04 Dec 2013 09:54:02 GMT
       
  • Periodontitis and Buerger’s Disease: Recent Advances
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Verica Pavlic, Vesna Vujic-Aleksic, Nina Zubovic, Mirjana Gojkov-Vukelic.
      Buerger’s disease (BD) is a relatively rare thrombotic, occlusive and non-atherosclerotic clinical syndrome of unknown etiology. In recent years, numerous epidemiological studies confirmed the strong association between chronic anaerobic periodontal infection and development of cardiovascular diseases, including BD. Therefore, the aim of this study is to clarify association between periodontal pathogens and Buerger’s disease. Confirmation of presence and identification of periopathogens in patients with BD can be considered crucial in developing novel therapies for BD. Further, periodontal therapy will lead to eventual improvement of BD patients’ condition.

      PubDate: Wed, 04 Dec 2013 09:52:53 GMT
       
  • Comparability of Diagnostic Methods: Proximal Endoscopy, CT and EUS in
           Determining Stomach Tumor Localization and their Importance in the
           Preoperative Analysis of Process Progression
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Zora Vukobrat-Bijedic, Azra Husic-Selimovic, Amela Sofic, Nina Bijedic, Bisera Gogov, Amila Mehmedovic, Aida Saray, Sanjin Glavas, Ivana Bjelogrlic.
      Introduction: Gastric cancer is one of the most common tumors in humans and is on the 14th place by frequency in the United States and it is at the 8th place by the mortality rate. In the world it takes seventh place by incidence. Today prevail the opinion and the surveys show, that it is twice as common in men as compared to women. Although there are advancements in diagnostics it must be noted that gastric cancer is still discovered late and when it already has metastasized, so that the therapeutic approach is limited and low survival rate. Patients and Methods: The study was retrospective-prospective, which covered the period from 2011 to 2012 and was performed at the Clinic of Gastroenterohepatology, Clinical Center of Sarajevo University. The study included 50 patients with gastric cancer, 34 men and 16 women. All patients underwent gastroscopy and according to tumor lesions localization divided into 3 regions: cardia, corpus and antropyloric region. Tumor lesions were biopted with histologically confirmation of gastric wall cancer. All patients underwent CT of gastric wall, CT of the abdomen and in some cases EUS was performed also. Goal: To prove by available diagnostic methods (endoscopy, CT and EUS) the presence of gastric cancer, histologically validate it and determine localization according to regions. To determine by CT the thickness of the stomach wall or the penetration of tumor lesions, the presence of enlarged lymph nodes and possible metastases. Record by EUS the progression of malignant processes in depth to layers of the wall, surrounding tissue metastases and enlarged lymph nodes. Determine the correlation between the measured parameters. Results: Our study showed that the localization of tumors at the cardia was represented in 15.31%, corpus in 17.36% and antropyloric region 16.33%. Median age he was 65.5 years with a standard deviation of 11.04. We failed to demonstrate a statistically significant difference in verified findings by EUS and age as well as endoscopic findings and age. Also there is no statistically significant difference between the CT scan and endoscopy XT = 5.99 and α = 0.05 = 0.63 XE, XE XT) and endoscopic findings and age (XT = 3.84 at α = 0.01, = 0.01 XE, XE> XT). Conclusion: Our study showed that gastric cancer are more common in men than women, metastases were more common in the elderly population, there were no significant deviations from the endoscopic findings and CT findings. EUS was performed in a small number of patients and showed as a good method because it gave accurate information about the penetration depth. Endoscopy, EUS and CT are ideal methods in diagnostic and staging of gastric cancer before the surgery.

      PubDate: Wed, 04 Dec 2013 09:50:13 GMT
       
  • Development of Common Data Elements to Provide Tele self-Care Management
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Fatemeh Rangraz Jeddi, Mohammad Reza Rezaiimofrad.
      Background: Self-care management could empower patients to management of their health. Tele-health is the remote exchange of data between a patient and medical staff to improve healthcare quality. The aim of this research was developing common data elements to provide Tele self-care management and improve quality of care. Materials and methods: this was a cross-sectional study based on Delphi approach was done in 2011. Data was extracted by three sessions’ of conversation with 20 faculty members. Data had more than 75% agreement was inserted in minimum data element list, data with lower than 50% agreement was considered as failed data and whom was agreed between 50%-75% of participants were reconsidered for conversation until three sessions and after re-voting it was failed or accepted. Results: Results showed that self-care divides in three main categories and also some sub-categories including:1-Immunity and Safety with two subcategories (A: Prevention of Disease and B: Awareness and Knowledge about Disease); 2-Health Security and Maintains in six subcategories (A: Labratoary Test Results; B: Vital Data Monitoring; C: Rehabilitation; D: Drug Information; E: Follow up and F: Dental Health), 3- Well-Being Education in four subcategories (A: Nutrition; B: Health Promotion; C: Life Style Improvement and D: Patient Activity). Discussion: Consideration of all aspects of self management including information about prevention of disease, knowledge about disease, laboratory test result, vital signs monitoring, rehabilitation, drug information, follow up, dental health, nutrition, health promotion, life style improvement and patient activities is necessary.

      PubDate: Wed, 04 Dec 2013 09:48:43 GMT
       
  • Application of a Diode Laser in the Reduction of Targeted Periodontal
           Pathogens
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Mirjana Gojkov-Vukelic, Sanja Hadzic, Amira Dedic, Rijad Konjhodzic, Edina Beslagic.
      Introduction: Periodontal disease belongs to a group of diseases with more than one cause, it is a disease of a multifactorial etiology. Although bacteria are the main cause of the disease, immunoinflammatory reaction of the host is responsible for the majority of destructive changes in periodontal tissue. The main issue in the evaluation of the success of periodontal therapy is the pluralism of the bacteria and their dynamic changes during the duration, on the one hand, and the possible inaccuracy of classical microbiological analysis in determination of the dominant role of a microorganism, or the success of its reduction or elimination, on the other. Thanks to advances of microbiology and technological development, it is possible to make an assessment of specific microorganisms in a large number of samples of subgingival plaque with extreme precision, using checkerboard DNA-DNA hybridization and method of polymerase chain reaction (PCR). The development of laser technology and the discovery of its significant antimicrobial effects have introduced and presented this treatment modality as a possible auxiliary method of periodontitis treatment. Materials and Methods: The sample for the study estimating the efficiency of application of diode lasers in the reduction of periodontal pockets consisted of 1164 periodontal pockets in 24 subjects of both sexes. For laser irradiation of periodontal pockets a diode laser was used, a low-power laser (SmilePro 980, Biolitec, Germany), working in a mode precisely tuned for treatment of periodontal pockets. All subjects underwent: general anamnesis, periodontal status, and orthopantogram radiograph analysis. Following a standard periodontal preparation, a sample of subgingival plaque was collected for molecular-biological analysis (real-time PCR method) prior to laser irradiation of periodontal pockets, immediately following the irradiation, and during the control examination 3 months after irradiation. Results: The results of the molecular-biological analysis of target periodontal pathogens Actinobacillus (Aggregatibacter) actinomycetemcomitans (AA) and Porphyromonas gingivalis (PG) isolated from periodontal pockets prior to laser irradiation, immediately after laser irradiation, and at the control examination after 3 months were processed statistically (using real-time PCR method). The results showed that there was a statistically significant decrease in CT values ​​for the tested bacteria immediately after treatment and the control examination, compared with the level of CT values ​​for the same bacteria before treatment. Conclusions: Based on the obtained results, we concluded that diode laser irradiation reduces the number of active periodontal pathogens. We believe that the use of diode lasers, as a supplementary method in the treatment of periodontal disease, is extremely useful and efficient, and can be recommended as part of standard clinical practice.

      PubDate: Wed, 04 Dec 2013 09:47:03 GMT
       
  • H-indices of Academic Pediatricians of Mashhad University of Medical
           Sciences
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Kianifar Hamidreza, Akhoondian Javad, Sadeghi Ramin, Zarifmahmoudi Leili.
      Background: Web of Science, Scopus, and Google Scholar are three major sources which provide h-indices for individual researchers. In this study we aimed to compare the h-indices of the academic pediatricians of Mashhad University of Medical Sciences obtained from the above mentioned sources. Method: Academic pediatrician who had at least 5 ISI indexed articles entered the study. Information required for evaluating the h-indices of the included researchers were retrieved from official websites Web of Science (WOS), Scopus, and Google Scholar (GS). Correlations between obtained h-indices from the mentioned databases were analyzed using Spearrman correlation coefficient. Ranks of each researcher according to each database h-index were also evaluated. Results: In general, 16 pediatricians entered the study. Computed h-indices for individual authors were different in each database. Correlations between obtained h-indices were: 0.439 (ISI and Scopus), 0.488 (ISI and GS), and 0.810 (Scopus and GS). Despite differences between evaluated h-indices in each database for individual authors, the rankings according to these h-indices were almost similar. Conclusion: Although h-indices supplied by WOS, SCOPUS, and GS can be used interchangeably, their differences should be acknowledged. Setting up “ReasercherID” in WOS and “User profile” in GS, and giving regular feedback to SCOPUS can increase the validity of the calculated h-indices.

      PubDate: Wed, 04 Dec 2013 09:45:39 GMT
       
  • Principles and Ethics in Scientific Communication in Biomedicine
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Doncho Donev.
      Introduction and aim: To present the basic principles and standards of scientific communication and writing a paper, to indicate the importance of honesty and ethical approach to research and publication of results in scientific journals, as well as the need for continuing education in the principles and ethics in science and publication in biomedicine. Methods: An analysis of relevant materials and documents, sources from the internet and published literature and personal experience and observations of the author. Results: In the past more than 20 years there is an increasingly emphasized importance of respecting fundamental principles and standards of scientific communication and ethical approach to research and publication of results in peer review journals. Advances in the scientific community is based on honesty and equity of researchers in conducting and publishing the results of research and to develop guidelines and policies for prevention and punishment of publishing misconduct. Today scientific communication standards and definitions of fraud in science and publishing are generally consistent, but vary considerably policies and approach to ethics education in science, prevention and penal policies for misconduct in research and publication of results in scientific journals. Conclusion: It is necessary to further strengthen the capacity for education and research, and raising awareness about the importance and need for education about the principles of scientific communication, ethics of research and publication of results. The use of various forms of education of the scientific community, in undergraduate teaching and postgraduate master and doctoral studies, in order to create an ethical environment, is one of the most effective ways to prevent the emergence of scientific and publication dishonesty and fraud.

      PubDate: Wed, 04 Dec 2013 09:44:34 GMT
       
  • Electrocardiographic Screening of Emphysema: Lead aVL or Leads III and
           I'
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Lovely Chhabra, David H. Spodick.


      PubDate: Sat, 10 Aug 2013 03:50:28 GMT
       
  • New Medical Education System: Implementation of Informatic Technology and
           Holistic Approach Concept
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Viroj Wiwanitkit.


      PubDate: Sat, 10 Aug 2013 03:49:28 GMT
       
  • On the occasion of the International Scientific Conference
           “Publishing Integrity and Misconduct in Biomedicine”
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Izet Masic.


      PubDate: Sat, 10 Aug 2013 03:48:04 GMT
       
  • Hb H Interference on Measurement Of HbA1c With Ion-Exchange HPLC
    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Mehmet Agilli, Halil Yaman, Fevzi Nuri Aydinl, Tuncer Cayci, Irfan Sener.
      In this article, an interference caused by hemoglobin H (Hb H), during the measurement of hemoglobin A1c (HbA1c) with ion exchange high pressure liquid chromatography (HPLC) method, was presented in blood sample of a 20-year-old male patient. HbA1c measurement was performed with Agilent 1200 HPLC system using a commercial Recipe HbA1c ion-exchange column. Hemoglobin electrophoresis was performed with Interlab G26 agarose electrophoresis automated compact system. HbA1c level was 18.2% and HbA0 level was 81.5% with ion-exchange HPLC method. Patient’s fasting serum glucose was assessed before HbA1c measurement and the result was 165 mg/dL (9.16 mmol/L). On the other hand, the result of HbA0 was 87.9%, Hb H was 10.8% and Hb A2 was 1.3% with electrophoresis. Whole blood test values were within reference ranges except MCV. MCV value was 79.6 fL. It is important to keep in mind that HbA1c level might be considered falsely high with ion-exchange HPLC method because of Hb H containing sample.

      PubDate: Sat, 10 Aug 2013 03:45:56 GMT
       
 
 
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