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Journal Cover Acta Informatica Medica
  This is an Open Access Journal Open Access journal
     ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
     Published by ScopeMed Homepage  [77 journals]   [H-I: 2]
  • EASE Guidelines for Authors and Translators of Scientific Articles to be
           Published in English

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      European Association of Science Editors (EASE).
      This concise and readable set of editorial guidelines was first published by the European Association of Science Editors (EASE) in 2010 and is updated annually. It is freely available in more than 20 languages at The document is aimed to help scientists worldwide in successful presentation of their research results and in correct translation of manuscripts into English. Moreover, it draws attention to ethical issues, like authorship criteria, plagiarism, conflict of interests, etc. Eight appendices provide examples or more detailed information on selected topics (Abstracts, Ambiguity, Cohesion, Ethics, Plurals, Simplicity, Spelling, and Text-tables). Widespread use of EASE Guidelines should increase the efficiency of international scientific communication.

      PubDate: Sun, 15 Jun 2014 10:43:47 GMT
  • The Use of Smart phones in Ophthalmology

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Edita Zvornicanin, Jasmin Zvornicanin, Bahrudin Hadziefendic.
      Smart phones are being increasingly used among health professionals. Ophthalmological applications are widely available and can turn smart phones into sophisticated medical devices. Smart phones can be useful instruments for the practice of evidence-based medicine, professional education, mobile clinical communication, patient education, disease self-management, remote patient monitoring or as powerful administrative tools. Several applications are available for different ophthalmological examinations that can assess visual acuity, color vision, astigmatism, pupil size, Amsler grid test and more. Smart phones can be useful ophthalmic devices for taking images of anterior and posterior eye segment. Professional literature and educational material for patients are easily available with use of smart phones. Smart phones can store great amount of informations and are useful for long term monitoring with caution for patient confidentiality. The use of smart phones especially as diagnostic tools is not standardized and results should be carefully considered. Innovative role of smartphone technology and its use in research, education and information sharing makes smart phones a future of ophthalmology and medicine.

      PubDate: Sun, 15 Jun 2014 10:42:16 GMT
  • Changes in the Muscle Strength of the Elbow Flexors Following a Six-week
           Experimental Procedure in Adolescents Monitored Through Isokinetic and
           Motor Tests

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Vladimir Vuksanovic, Zoran Handjiski, Eli Handjiska.
      A group of 7 subjects underwent an experimental procedure which studied the potential changes in the maximal strength of the non-dominant arm elbow flexors. The programme duration was limited to 6 weeks during which the subjects practiced exercises 3 times a week, 3 series, on a Scott bench. Individual approach was applied to the external load and it was designed so that the weight being lifted would increase if the number of lifts in one series would exceed 3. The subjects were monitored through the one-repetition maximum 1 RM motor test and the isokinetic tests performed on biodex system, tested in 3 time periods (at the beginning, after 3 weeks, and after the 6th week). Of the 6 isokinetic tests, only the test for the maximum torque and the time for achieving the maximum torque have shown statistically important changes in terms of reduction in values, which was not expected. The one-repetition maximum test, unlike the isokinetic tests, has shown statistically important increase of the maximal muscle strength of 32.1% after the third week of exercising, and 46.8% after the six weeks of exercising. The statistical test for the correlation between the two variables has shown low correlation between these two tests. The values of the data of the two test types have not shown any correspondence among the subjects possibly due to the type of performance of the maximal muscle load during exercises, performed in conditions identical to the one-repetition maximum test, with similar and yet different conditions in the case of isokinetic tests. Most probably, due to the conditions in which the exercises and the tests took place, there is difference in the obtained results.

      PubDate: Sun, 15 Jun 2014 10:40:33 GMT
  • Contribution of Indian Pediatric Dentists to Scientific Literature During
           2002–2012: a Bibliometric Analysis

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jatinder Kaur Dhillon, Namrata C Gill.
      Introduction: Bibliometric analysis of publications is necessary to enable clinicians to make evidence based sound clinical decisions. It will also help policy makers & institutions to frame their decisions and policies so as to improve the quality of dental research in India. AIM: The purpose of this study is to identify publication output as well as descriptively and quantitatively characterize the contribution of Indian pediatric dentists to scientific literature through publication trend analysis from 2002 to 2012. Settings and design: Cross sectional analytical study. Material and method: A bibliometric analysis of publications by Indian pediatric dentists during 2002 to 2012 was performed on data collected from PubMed – MEDLINE database. Only the first author’s affiliations were considered and the publications were categorized according to the following variables: year of publication, number of authors, state of origin, type of article, reach of journal and country of publication. Results: There were 817 articles by Indian pediatric dentists during the study period. Of all the articles 399 (48.8%) were original research, 377(46.1%) were case reports and 41 (5.0%) were reviews. The inter-annual variation between the reach, country of publication of the journal and type of articles is presented. The growth trend analysis was performed and predictions are presented. Conclusion: There has been an increase in the number of publications by Indian pediatric dentists and most of the published work comprises of original research. The potential use of this data is discussed.

      PubDate: Sun, 15 Jun 2014 10:38:47 GMT
  • Scientific production of Sports Science in Iran: A Scientometric Analysis

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Mousa Yaminfirooz, Hasan Siamian, Mohammad Ali Jahani, Masoud Yaminifirouz.
      Background: Physical education and sports science is one of the branches of humanities. The purpose of this study is determining the quantitative and qualitative rate of progress in scientific Production of Iran’s researcher in Web of Science. Methods: Research Methods is Scientometric survey and Statistical Society Includes 233 Documents From 1993 to 2012 are indexed in ISI. Results: Results showed that the time of this study, Iranian researchers’ published 233 documents in this base during this period of time which has been cited 1106(4.76 times on average). The H- index has also been 17. Iran’s most scientific productions in sports science realm was indexed in 2010 with 57 documents and the least in 2000. Conclusions: By considering the numbers of citations and the obtained H- index, it can be said that the quality of Iranian’s articles is rather acceptable but in comparison to prestigious universities and large number of professors and university students in this field, the quantity of outputted articles is very low.

      PubDate: Sun, 15 Jun 2014 10:35:45 GMT
  • Medical Universities Educational and Research Online Services:
           Benchmarking Universities’ Website Towards E-Government

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Mehrdad Farzandipour, Zahra Meidani.
      Background: Websites as one of the initial steps towards an e-government adoption do facilitate delivery of online and customer-oriented services. In this study we intended to investigate the role of the websites of medical universities in providing educational and research services following the E-government maturity model in the Iranian universities. Methods: This descriptive and cross- sectional study was conducted through content analysis and benchmarking the websites in 2012. The research population included the entire medical university website (37). Delivery of educational and research services through these university websites including information, interaction, transaction, and Integration were investigated using a checklist. The data were then analyzed by means of descriptive statistics and using SPSS software. Results: Level of educational and research services by websites of the medical universities type I and II was evaluated medium as 1.99 and 1.89, respectively. All the universities gained a mean score of 1 out of 3 in terms of integration of educational and research services. Conclusions: Results of the study indicated that Iranian universities have passed information and interaction stages, but they have not made much progress in transaction and integration stages. Failure to adapt to e-government in Iranian medical universities in which limiting factors such as users’ e-literacy, access to the internet and ICT infrastructure are not so crucial as in other organizations, suggest that e-government realization goes beyond technical challenges.

      PubDate: Sun, 15 Jun 2014 10:34:23 GMT
  • Quality Assessment of Persian Mental Disorders Websites Using the
           Webmedqual Scale

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Leila Shahrzadi, Shahin Mojiri, Sima Janatian, Behjat Taheri, Hasan Ashrafi-rizi, Zeinab Shahrzadi, Razieh Zahedi.
      Introduction: Nowadays, anyone with any level of Internet knowledge can act as producer and distributor of information. It differs from most traditional media of information transmission, lack of information control and lack of quality management to contents. This leads to quality of health information on the internet is doubtful. The object of this study is guidance patients to select valid mental disorders and determine the quality of Persian mental disorders websites. Methods: The sample of this study comprised 29 Persian mental disorders websites that were chosen by searching the Google, Yahoo and AltaVista search engines for the Persian equivalents of the three concepts “depression,” “anxiety,” and “obsession”. website was created by individuals or organizations. Data collection was performed with the WebMedQual checklist. Websites was assessed based on indicators as content, authority of source, design, accessibility and availability, links, user support, and confidentiality and privacy (Maximum score for any website was 83, mean score 41.5 and minimum score was 0). Collected data analyzed by one sample T- test in SPSS 20. Findings presented by Mean score and optimal score. Results: Based on the WebMedQual scale the mean score of Persian mental disorders websites in sex constructs including “content” (7.02±2.10), “authority of source” (4.71±1.96),“accessibility and availability” (2.19±0.47), “links” (1.45±0.97), “user support” (4.28±1.33), and“confidentiality and privacy” (2.81±2.81) are poor and below average, but the score for the “design” (9.17± 1.59) is above average. The best website of mental disorders was that of the “IranianPsychological Association”. Conclusions: According to the results, only one website obtained the average score, so the quality of Persian mental disorders websites is low. Therefore, it is essential for users to criticize websites’ content and not trust them before evaluating them. It is better to use the ranked list websites or search on the internet by help information experts.

      PubDate: Sun, 15 Jun 2014 10:32:47 GMT
  • A Survey on the Users’ Satisfaction with the Hospital Information
           Systems (HISs) based on DeLone and McLean’s Model in the
           Medical-Teaching Hospitals in Isfahan City

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Sakineh Saghaeiannejad-Isfahani, Maryam Jahanbakhsh, Mahboobeh Habibi, Razieh Mirzaeian, Mansoreh Nasirian, Javad Sharifi Rad.
      Background and purpose: The user’s satisfaction with information system in fact denotes the extent the user is satisfied with the system’s achievement in fulfilling his/her information requirements. This study tries to explore the users’ satisfaction with hospital information systems (HISs) based on DeLone and McLean’s model focusing on the medical-teaching hospitals of Isfahan city. Methodology: This study which was applied and descriptive-analytical in nature was carried out in the medical-teaching hospitals of Isfahan city in 2009. Research population consisted of the system users from which a sample was selected using random sampling method. The size of the sample was 228. Data collection instrument was a self-developed questionnaire produced based on the satisfaction criterion in the DeLone and McLean’s model. Its content validity was assessed based on the opinions given by the computer sciences professionals with its estimated Cronbach’s alpha found to be 92.2%. The data were analyzed using SPSS software. Findings: As the findings of the study showed, the differences among the mean scores obtained for the satisfaction with different kinds of HISs in use in the hospitals were statistically significant (p value≤0.05). Generally, Kowsar System (old version) and Pouya Samaneh Diva system gained the highest and lowest mean scores for the criterion in question, respectively. The overall mean score for the satisfaction was 54.6% for different types of systems and 55.6% among the hospitals. Conclusion: Given the findings of the study, it can be argued that based on the used model, the level of users’ satisfaction with the systems in question was relatively good. However, to achieve the total optimum condition, when designing the system, the factors affecting the enhancement of the users’ satisfaction and the type of hospital activity and specialty must be given special consideration.

      PubDate: Sun, 15 Jun 2014 10:31:22 GMT
  • Importance of Alpha-adrenergic Receptor Subtypes in Regulating of Airways
           Tonus at Patients with Bronchial Asthma

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Pellumb Islami, Ali Ilazi, Arianit Jakupi, Sadi Bexheti, Hilmi Islami.
      Background: In this work, effect of Tamsulosin hydrochloride as antagonist of alpha1A and alpha1B- adrenergic receptor and effect of Salbutamol as agonist of beta2- adrenergic receptor in patients with bronchial asthma and increased bronchial reactibility was studied. Methods: Parameters of the lung function are determined by Body plethysmography. Raw and ITGV were registered and specific resistance (SRaw) was also calculated. Tamsulosin was administered in per os way as a preparation in the form of the capsules with a brand name of “Prolosin”, producer: Niche Generics Limited, Hitchin, Herts. Results: Results gained from this research show that blockage of alpha1A and alpha1B- adrenergic receptor with Tamsulosin hydrochloride (0.4 mg and 0.8 mg in per os way) has not changed significantly (p> 0.1) the bronchomotor tonus of tracheobronchial tree in comparison to the inhalation of Salbutamol as agonist of beta2- adrenergic receptor (2 inh. x 0.2 mg), (p < 0.05). Arterial blood pressure showed no significant decrease following the administration of the dose of 0.8 mg Tamsulosin. Conclusion: This suggests that the activity of alpha1A and alpha1B- adrenergic receptor in the smooth musculature is not a primary mechanism which causes reaction in patients with increased bronchial reactibility, in comparison to agonists of beta2 – adrenergic receptor which emphasizes their significant action in the reduction of specific resistance of airways.

      PubDate: Sun, 15 Jun 2014 10:30:12 GMT
  • Potential Role of Lung Ventilation Scintigraphy in the Assessment of COPD

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Vesna Cukic, Amela Begic.
      Objective: To highlight the importance of the lung ventilation scintigraphy (LVS ) to study the regional distribution of lung ventilation and to describe most frequent abnormal patterns of lung ventilation distribution obtained by this technique in COPD and to compare the information obtained by LVS with the that obtained by traditional lung function tests. Material and methods: The research was done in 20 patients with previously diagnosed COPD who were treated in Intensive care unit of Clinic for pulmonary diseases and TB “Podhrastovi” Clinical Center, University of Sarajevo in exacerbation of COPD during first three months of 2014. Each patient was undergone to testing of pulmonary function by body plethysmography and ventilation/perfusion lung scintigraphy with radio pharmaceutics Technegas, 111 MBq Tc -99m-MAA. We compared the results obtained by these two methods. Results: All patients with COPD have a damaged lung function tests examined by body plethysmography implying airflow obstruction, but LVS indicates not only airflow obstruction and reduced ventilation, but also indicates the disorders in distribution in lung ventilation. Conclusion: LVS may add further information to the functional evaluation of COPD to that provided by traditional lung function tests and may contribute to characterizing the different phenotypes of COPD.

      PubDate: Sun, 15 Jun 2014 10:28:37 GMT
  • Endoscopic Management of Vesicoureteral Reflux in Children in Kosova

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Murat Berisha, Nexhmi Hyseni, Sejdi Statovci, Salih Grajqevci, Butrint Xhiha.
      Introduction: Vesicoureteral reflux (VUR) in children has been treated with subureteric deflux injection of Deflux (dextranomer hyaluronic acid copolymer) since 2009. The aim of this study was to analyze the results of endoscopic treatment of VUR in our clinic. Methods: Between March 2009 and December 2013, fifty-five children underwent endoscopic subureteral injection of Deflux in 78 ureters. Two months postoperatively voiding cystourethrogram (VCUG) was performed. This study examined the disappearance of VUR and urinary tract infection (UTI) as well as the quality of life during long-term follow-up. Results: The study included 55 patients (40 females and 15 males) with 78 refluxing ureters. There were 22 refluxed ureters altogether and 33 children had a unilateral reflux (two duplicated systems). All patients were treated, from the age 6 months up to 12 years old. The mean age of patients was 5.2 years. There has been no complications, but with few recurrences. In 6 patients (16.6%), endoscopic treatment with deflux was done twice, while in three patients (8.5%), the endoscopic treatment with deflux was performed three times, because of recurrence. Conclusion: We recommend the use of endoscopic Deflux injection as first line treatment for children with VUR .Endoscopic subureteral injection of Deflux is a minimally invasive method for VUR treatment in pediatric patients and is associated with low morbidity.

      PubDate: Sun, 15 Jun 2014 10:27:05 GMT
  • Colonoscopy as a Method of Choice in the Diagnosis of Colorectal Cancer

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Sead Buturovic.
      Introduction: Epidemiological characteristics of colorectal cancer indicate that in the U.S. colorectal cancer is the second leading cause of death from malignancy, just behind lung cancer. In the 2000 there were approximately 130,200 new cases, of which 56,300 had lethal outcome. In the past 15 years, the incidence and mortality rate has been declining, especially in women. Colorectal cancer is mainly found in people older than 50 years. Carcinoembryonic antigen (CEA) is insufficiently specific for the early detection of the disease. Its normal value is less than 5 g/L in the serum. Elevated levels of CEA after surgery indicate a lack of radical surgery, residual neoplasm, hidden distant metastases or recurrent disease. Unfortunately, only 10-15% of patients with recurrent disease can be successfully re-operated (isolated metastases in the liver or lungs). Colorectal cancer is predominantly adenocarcinoma, the tumor has relatively slow growth. While symptoms occur relatively early, distant metastases have relatively late appearance. Goals: The goals of this study were to remind the fundamental facts about the nature of this disease, to stress the importance of early detection of BC-screening programs, to draw attention to contemporary attitudes in the field of diagnosis and treatment of colorectal cancer, and to show the experience in the treatment of this disease at the Surgical Departments of the General Hospital in Konjic. Results: In the period from 2008-2012 years, at the Surgical Department of the General Hospital in Konjic surgically treated are 34 patients who had colorectal malignancy. There were 21 (65 %) male and 13 females (35%). All patients belonged to the age group of 50-75 years. Only five patients or 15 % prior to admission to the hospital had been diagnosed with a malignant process. All others, or 85% of the total sample, were admitted to the hospital as emergency cases (erosive gastritis), and after, shorter preparation underwent surgery. Only five (15%) of patients were admitted electively, already diagnosed with colorectal tumors by colonoscopy. Total number of lethal outcomes at the department was 8 (24%). Three patients died due to cardio-respiratory failure and MOF, and 5 patients due to anastomotic failure and septic shock. Conclusion: In conclusion we can say that in our institution it is necessary to obtain the proper equipment (colonoscope) and educate personnel, so we can introduce colonoscopy as the mandatory screening method of examination, particularly for vulnerable groups.

      PubDate: Sun, 15 Jun 2014 10:25:31 GMT
  • Sensitivity of EUS and ERCP Endoscopic Procedures in the Detection of
           Pancreatic Cancer During Preoperative Staging Correlated with CT and CT
           Angiography Imaging Methods

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zora Vukobrat-Bijedic, Azra Husic-Selimovic, Nina Bijedic, Srdjan Gornjakovic, Amela Sofic, Bisera Gogov, Ivana Bjelogrlic, Amila Mehmedovic, Sanjin Glavas.
      The goal: The goal of this work was to give advantage to EUS as endoscopic method in diagnosis and following therapeutic treatment of pancreatic cancer in relation to radiological methods of CT and CTA. Material and Methods: The study included 49 patients, 20 women and 29 men hospitalized at the Clinic for gastroenterohepatology, due to suspicion on pancreatic cancer during observed 2 years period. All cancers were histologically and cytologically confirmed. The patients underwent ERCP as a mandatory part of staging and all patients underwent endoscopic ultrasound as well as CT or CT angiography. Results: Testing of differences was carried out using Fisher’s exact test in open-source software R. The following characteristics were tested: involvement of the blood vessels, lymph nodes, metastases, tumor size and duodenum infiltration. Results showed statistically significant difference at the 0.05 level for EUS, CT and CT angiography. Risk ratio showed that EUS is less effective in detecting infiltration of blood vessels within a malignant process then CTA where RR=0.52, CI 0.2–1.38, p-value=0.33. EUS and CTA are equal in the diagnosis of enlarged lymph nodes affected by malignancy where RR=1.3, CI 0.75–1.42, p-value=0.09. Comparison according to distant metastases showed that EUS is less effective compared to CT in approximately 30% of cases. In the diagnosis of duodenal infiltration EUS is in 5% of cases less accurate than the CT with the RR=0.95, CI 0.27–3.32, p-value=0.76, but the CTA method is more efficient because the comparison of EUS and CTA showed RR=12.52, CI 0.2–1.38, p-value=0.33. EUS as a diagnostic method is dominant in determining the size of malignant lesions located in the pancreas as compared to CT and CTA. Conclusion: EUS as endoscopic method compared to CT and CTA is one of the more invasive methods of examination but due to its ability to be performed immediately, to locate a changes smaller than 5 mm and the target biopsy option, to measure the change and that in many cases determine the relationship of malignant lesions with blood vessels, along with visualization of the surrounding lymph nodes and metastases in neighboring organs, we may give this method an advantage over other methods in the preoperative staging of patients with pancreatic cancer.

      PubDate: Sun, 15 Jun 2014 10:24:07 GMT
  • Effect of Initial Conditions on Reproducibility of Scientific Research

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Benjamin Djulbegovic,, Iztok Hozo.
      Background: It is estimated that about half of currently published research cannot be reproduced. Many reasons have been offered as explanations for failure to reproduce scientific research findings- from fraud to the issues related to design, conduct, analysis, or publishing scientific research. We also postulate a sensitive dependency on initial conditions by which small changes can result in the large differences in the research findings when attempted to be reproduced at later times. Methods: We employed a simple logistic regression equation to model the effect of covariates on the initial study findings. We then fed the input from the logistic equation into a logistic map function to model stability of the results in repeated experiments over time. We illustrate the approach by modeling effects of different factors on the choice of correct treatment. Results: We found that reproducibility of the study findings depended both on the initial values of all independent variables and the rate of change in the baseline conditions, the latter being more important. When the changes in the baseline conditions vary by about 3.5 to about 4 in between experiments, no research findings could be reproduced. However, when the rate of change between the experiments is ≤2.5 the results become highly predictable between the experiments. Conclusions: Many results cannot be reproduced because of the changes in the initial conditions between the experiments. Better control of the baseline conditions in-between the experiments may help improve reproducibility of scientific findings.

      PubDate: Sun, 15 Jun 2014 10:22:48 GMT
  • My View on Plagiarism

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Ermin Begovic.

      PubDate: Mon, 17 Mar 2014 12:33:11 GMT
  • Spinal Dissemination of Intracranial Glioblastoma in Bevacizumab Era: a
           Potential Bevacizumab-induced Mechanism

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Gentian Kaloshi, Arben Roji, Arsen Seferi, Bujar Cakani, Teona Bushati, Ermir Roci, Mentor Petrela.
      Spinal metastasis, a devastating neurologic complication of intracranial glioblastomas is not as uncommon as initially thought. It varies from 25% in supratentorial glioblastomas to 60% in infratentorial glioblastomas. The underlying pathogenesis spinal spread of high-grade gliomas is still unclear. To date, no causal responsibility of Bevacizumab (BEV) was noted. Here, we report for the first time, a case of thoracic intramedullary metastases from a cerebral glioblastoma pre-treated with BEV. A critical and exhaustive review is provided.

      PubDate: Mon, 17 Mar 2014 12:30:04 GMT
  • Use of the Toric Intraocular Lens for Keratoconus Treatment

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jasmin Zvornicanin, Emir Cabric, Vahid Jusufovic, Zlatko Musanovic, Edita Zvornicanin.
      A 50 year old man presented to Eye clinic University clinical centre Tuzla with bilateral visual impairment. Clinical examination revealed low visual acuity and keratoconus in both eyes, white cataract in right eye and diabetic retinopathy in left eye. Ultrasonography examination was normal. The patient underwent Trypan blue capsule staining, phacoemulsification and implantation of intraocular lens Alcon AcrySof SN60T9 16 D spherical and 6.0 D cylinder power. Phacoemulsification went uneventful and early postoperative recovery was successful. Visual acuity improved to 0,8 and fundus examination revealed background diabetic retinopathy. Postoperative follow up two years after surgery showed no signs of keratoconus progression and visual acuity maintained the same.

      PubDate: Mon, 17 Mar 2014 12:27:41 GMT
  • A Roadmap to Pre-Implementation of Electronic Health Record: the Key Step
           to Success

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Marjan Ghazisaeidi, Maryam Ahmadi, Farahnaz Sadoughi, Reza Safdari.
      Introduction: Initial attempts are made to implement electronic health record (EHR) in Iran, the present study aim is developing a proper roadmap to EHR in pre-implementation phase by expert views on the matter. Method: An initial framework was developed for pre- implementation based on reviewing literature on EHR implementation and descriptive-comparative with qualitative approaches in five countries. A questionnaire was designed in several sections using 47 main topics associated with pre-implementation. Cronbach’s alpha 0.89 confirmed the reliability of the data. Expert views were used to score each topic based on Likert scale and opinions were collected through Delphi. Then results analyzed using descriptive statistical analysis method. Result: Framework of EHR pre-implementation roadmap was presented in four phases: preliminaries, assessment, planning, and method of choosing system vendors. Priorities in each part were determined and reflected in the roadmap using expert views, analyses, and requirements of each phase. It seems strategic planning at different levels; assessment of needs; providing and managing financial resources, setting standards; examining the existing condition was determined as highest priorities in above phases. Conclusion: For successful implementation, developing national carefully-designed and well-documented EHR pre-implementing roadmap, Based on country situation, from strategic to operation level is necessary.

      PubDate: Mon, 17 Mar 2014 12:25:11 GMT
  • Cervical Length Measured by Transvaginal Ultrasonography and
           Cervicovaginal Infection as Predictor of Preterm Birth Risk

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Arnela Ceric Banicevic, Miroslav Popovic, Amela Ceric.
      Introduction: The study shows possibilities of transvaginal sonographic measurement of the cervix in prediction of premature birth risk. Goals: The aim of the study was to follow up the cervical length in the pregnant from 16th to 37th week, as well as to do a microbiological analysis of the vaginal and cervical flora and to identify relation between the cervical shortening and microbiological flora as well as with a premature birth. Material and methods: The investigation was conducted as a prospective study on two groups of female patients in Clinical Centre of Banja Luka. In the high risk group we had 8% of patients with cervical length bellow than 15mm, 30% of patients with cervical length from 15 to 25m and 62% of patients with cervical length bigger than 25mm. In the low risk group we had no patients with cervical length bellow 15mm, 95% of patients had cervical length bigger than 25mm and 5% of patients had cervical length from 15 do 25mm. Results: The regression coefficient of the cervical length in the high risk group was 0.44mm, while in the low risk group it was 0.26mm. In the high risk group 67.56% patients had a positive cervical smear finding, while in the low risk group it was 4%. A high premature birth (defined as birth before 36.6 weeks) incidence of 50% was presented in patients with cervical length bellow 15mm. In the group of patients with cervical length up to 25mm the premature risk incidence was 10.52±0.05. In the high risk group of patients with a positive cervical smear finding, regarding the cervical length the percentage was as follows; in the subgroup of 15mm length 88,89±11,87, in subgroup from 15 to 25mm was 62,07±11,43 and in the subgroup bigger than 25mm, 60.06±8.05. Conclusion: By the analysis of the first and second goal of our study we can conclude that ultrasound assessment of cervical length is simple and feasible in the 16th week of pregnancy in both groups, with high and low risk. The length of the cervix in this period is shorter in the high risk group compared with the low-risk group. This difference was not statistically significant, however, it clearly demonstrated connection between shorten length of the cervix with the preterm birth. A regression analysis shows that the shortening of the cervix length is more frequent in high risk group which is to be expected, bearing in mind that in this group, the risk of preterm delivery was significantly higher.

      PubDate: Mon, 17 Mar 2014 12:22:17 GMT
  • Experiences of Academic Members About their Professional Challenges: a
           Content Analysis Qualitative Study

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zohreh Shahhosseini, Mahmonier Danesh.
      Background: University faculty members of different disciplines in any country, by giving better quality services, will further accelerate the development of their respective countries. This study aims to explore the experiences of faculty members about their professional challenges. Aim: In this qualitative study, which was conducted in 2013, fifteen faculty members in the departments of clinical and basic sciences of Mazandaran university of Medical Sciences in northern Iran were chosen for semi-structured in-depth interviews by purposive sampling method. All tape-recorded data were fully transcribed and content analysis was performed. Results: After immersion and data analysis, three main themes were emerged including: “Imbalances in academic members’ tasks in different areas”, “Weakness of evaluation and promotion system” and “Failure to provide the infrastructure educational facilities”. The main themes and sub-themes are explained by the help of participants’ direct quotations. Conclusions: This study suggested that it is better to take effective measures to improve the faculty members’ situation and therefore increase their efficiency, effectiveness and productivity.

      PubDate: Mon, 17 Mar 2014 12:20:49 GMT
  • Proposed Use of the Computer as a Tool to Aid Analysis of Properties of
           Materials in Fixators of Spine

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Antonio Santos, Fernando Moreira.
      With objective of analyzing the mechanical behavior of the internal fixators of spine and of the bony structure, the pieces and the group were made (it structures bony x internal fixator) with the aid a software of solid modeling. The materials used in the rehearsals had been the titanium, now in the market and a castor oil polyurethane destined to the development of you implant bony.

      PubDate: Mon, 17 Mar 2014 12:16:37 GMT
  • A Comparative Study of the Proposed Models for the Components of the
           National Health Information System

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Maryam Ahmadi, Shahla Damanabi, Farahnaz Sadoughi.
      Introduction: National Health Information System plays an important role in ensuring timely and reliable access to Health information, which is essential for strategic and operational decisions that improve health, quality and effectiveness of health care. In other words, using the National Health information system you can improve the quality of health data, information and knowledge used to support decision making at all levels and areas of the health sector. Since full identification of the components of this system – for better planning and management influential factors of performance- seems necessary, therefore, in this study different attitudes towards components of this system are explored comparatively. Methods: This is a descriptive and comparative kind of study. The society includes printed and electronic documents containing components of the national health information system in three parts: input, process and output. In this context, search for information using library resources and internet search were conducted, and data analysis was expressed using comparative tables and qualitative data. Results: The findings showed that there are three different perspectives presenting the components of national health information system - Lippeveld and Sauerborn and Bodart model in 2000, Health Metrics Network (HMN) model from World Health Organization in 2008, and Gattini’s 2009 model. All three models outlined above in the input (resources and structure) require components of management and leadership, planning and design programs, supply of staff, software and hardware facilities and equipment. Plus, in the ‘’process’’ section from three models, we pointed up the actions ensuring the quality of health information system, and in output section, except for Lippeveld Model, two other models consider information products and use and distribution of information as components of the national health information system. Conclusion: the results showed that all the three models have had a brief discussion about the components of health information in input section. But Lippeveld model has overlooked the components of national health information in process and output sections. Therefore, it seems that the health measurement model of network has a comprehensive presentation for the components of health system in all three sections-input, process and output.

      PubDate: Mon, 17 Mar 2014 12:15:21 GMT
  • Reliability Assessment of Arthroscopic Findings Versus MRI in ACL Injuries
           of the Knee

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hristijan Kostov, Stojmenski Slavcho, Elena Kostova.
      Introduction: This study was conducted to analyze the reliability of clinical diagnosis in ACL tear injuries. Material and methods: All patients attending our clinic with knee pain from 2009 to 2013 underwent systematic and thorough clinical assessment. From one hundred and three patients with knee problems in 73 were arhroscopicaly diagnosed ACL tears. All these patients underwent therapeutic arthroscopic knee surgery. The clinical diagnosis was confirmed during this procedure. The accuracy, sensitivity and specificity were calculated based on these arthroscopic findings. Results: The accuracy of clinical diagnosis in our study was 82.5% for ACL tears. Our study revealed high sensitivity and specificity and almost high accuracy for ACL injuries of knee joint in comparison to arthroscopy. MRI is an appropriate screening tool for therapeutic arthroscopy, making diagnostic arthroscopy unnecessary in most patients. Conclusion: Magnetic resonance imaging is accurate and non invasive modality for the assessment of ligamentous injuries. It can be used as a first line investigation in patients with soft tissue trauma to knee.

      PubDate: Mon, 17 Mar 2014 12:13:55 GMT
  • Response of the Adrenergic System After Provoked Bronchoconstriction in
           Patients with Bronchial Asthma

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hilmi Islami, Ali Ilazi, Nijazi Gashi, Lirim Mustafa, Halit Maloku, Adelina Jashanica.
      Objective: In this paper, effect of the Tolazoline as antagonist of the alpha-2 adrenergic receptors in patients with bronchial asthma and chronic obstructive bronchitis was studied, and also the effect of stimulation with Hexoprenaline of beta-2 adrenergic receptor after bronchi-constriction caused with Propranolol, and Acetylcholine. Methods: Lung function parameters are determined with Body plethysmography. In patients with bronchial asthma and chronic obstructive bronchitis was registered resistance (Raw), was determined the amount of intrathoracic gas volume (ITGV), and specific resistance was calculated as well (SRaw). Aerosolization was done with standard aerosolizing machine–Asema. Results: The study included a total of 21 patients. Two hours after the inhalation of Propranolol, in experimental group, it was applied the blocker of alpha-2 adrenergic receptors (Tolazoline 20 mg / ml with inhalator ways), which did not cause changes in bronchomotor tonus of tracheobronchial system (p> 1.0). Meanwhile, at the same patient, stimulation of beta-2 adrenergic receptor with Hexoprenaline (2 inh x 0.2 mg) is associated with a significant decrease of the specific resistance of airways (SRaw, p < 0.01). Control group results show that after bronchi-constriction caused by Propranolol–aerosol (20 mg / ml) in patients with bronchial asthma and chronic obstructive bronchitis, an increase of specific resistance in airways was caused (SRaw, p < 0.01), which confirms the presence of hyper-reactive bronco-constrictor effects intermediated by vagal ways. Two hours after Propranolol, inhaled Hexorenaline has blocked the action of Propranolol, but not entirely. Furthermore, two hours after acetylcholine-aerosol (1 mg /ml) was applied, inhaled Ipratropium (2 inh x 1 mg) has fully blocked the action of chemical bronchoconstrictor mediators, causing a decline of specific resistance in the airways (SRaw; p < 0.01). Conclusion: This suggests that primary mechanism, which would cause reaction in patients with increased bronchial reactibility, is prevalence of the cholinergic system over adrenergic one, and not the relationship in between alpha-2 and beta-2 adrenergic receptors.

      PubDate: Mon, 17 Mar 2014 12:11:57 GMT
  • Comparison Between Impact Factor, Eigenfactor Metrics, and SCimago Journal
           Rank Indicator of Pediatric Neurology Journals

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hamidreza Kianifar, Ramin Sadeghi, Leili Zarifmahmoudi.
      Background: Impact Factor (IF) as a major journal quality indicator has a series of shortcomings including effect of self-citation, review articles, total number of articles, etc. In this study, we compared 4 journals quality indices ((IF), Eigenfactor Score (ES), Article Influence Score (AIS) and SCImago Journal Rank indicator (SJR)) in the specific Pediatric Neurology journals. Methods: All ISI and Scopus indexed specific Pediatric Neurology journals were compared regarding their 2011 IF, ES, AIS and SJR. Results: Fourteen pediatric Neurology journals were identified, 3 of which were only Scopus indexed and the others were both ISI and Scopus indexed. High correlation was found between IF and AIS (0.850). Correlations between IF and other indices were not that high. Self-citation, total article number and review articles were related to the IF and other indices as well as their ranks. English language and citation to non citable item didn’t have any effect on pediatric neurology journals ranks. Conclusion: Although all the above mentioned indicators can be used interchangeably, using all considered indices is a more appropriate way than using only IF for quality assessment of pediatric neurology journals.

      PubDate: Mon, 17 Mar 2014 12:10:05 GMT
  • Conceptual Model of Clinical Governance Information System for Statistical
           Indicators by Using UML in Two Sample Hospitals

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Fatemeh Rangraz Jeddi, Mehrdad Farzandipoor, Masoud Arabfard, Azam Haj Mohammad Hosseini.
      Objective: The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. Background: However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. Material and Methods: A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. Results: With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital’s clinical governance was required to create a database. Conclusion: Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems.

      PubDate: Mon, 17 Mar 2014 12:07:44 GMT
  • An Experimental Comparison of Two Different Technetium Source Activities
           Which Can Imitate Thyroid Scintigraphy in Case of Thyroid Toxic Nodule

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Ramë Miftari, Ferki Fejza, Xhavit Bicaj, Adem Nura, Valdete Topciu, Ismet Bajrami.
      Purpose: In cases of thyroid toxic autonomous nodule, anterior projection of Tc-99m pertechnetate image shows a hot nodule that occupies most, or the entire thyroid lobe with near-total or total suppression of the contra lateral lobe. In this case is very difficult to distinguish toxic nodule from lobe agenesis. Our interest was to estimate and determinate the rate of radioactivity when the source with high activity can make total suppression of the second source with low activity in same conditions with thyroid scintigraphy procedures. Material and methodology: Thyroid scintigraphy was performed with Technetium 99 meta stable pertechnetate. A parallel high resolution low energy collimator was used as an energy setting of 140 KeV photo peak for T-99m. Images are acquired at 200 Kilo Counts in the anterior projection with the collimator positioned as close as the patient’s extended neck (approximately in distance of 18 cm). The scintigraphy of thyroid gland was performed 15 minutes after intravenous administration of 1.5 mCi Tc-99m pertechnetate. Technetium 99 meta stable radioactive sources with different activity were used for two scintigraphies studies, performed in same thyroid scintigraphy acquisition procedures. In the first study, were compared the standard source with high activity A=11.2 mCi with sources with variable activities B=1.33 mCi; 1.03 mCi; 0.7 mCi; 0.36 mCi; and 0.16mCi) in distance of 1.5cm from each other sources, which is approximately same with distance between two thyroid lobes. In the second study were compared the sources with low activity in proportion 70:1(source A = 1.5 mCi and source B=0.021mCi). As clinical studies we preferred two different patents with different thyroid disorders. There were one patient with thyroid toxic nodule in the right lobe, therefore the second patient was with left thyroid nodule agenesis. Results: During our examination, we accurately determined that two radioactive sources in proportion 70:1 will be displayed as only one source with complete suppression of other source with low radioactivity. Also we found that covering of toxic nodules with lead cover (plaque), can allow visualization of activity in suppressed lobe. Conclusion: Our study concluded that total lobe suppression, in cases of patients with thyroid toxic nodule, will happened for sure, if toxic nodule had accumulated seventy times more radioactivity than normal lobe. Also we concluded that covering of the toxic nodule with lead plaque, may permit the presentation of radioactivity in suppressed nodule.

      PubDate: Mon, 17 Mar 2014 12:05:48 GMT
  • Sensitivity of Symptomatology Versus Diagnostic Procedures and
           Concentration of CEA and CA19–9 in the Early Detection of Colorectal

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zora Vukobrat-Bijedic, Azra Husic-Selimovic, Nina Bijedic, Admir Mujkic, Amela Sofic, Bisera Gogov, Amila Mehmedovic, Ivana Bjelogrlic, Sanjin Glavas, Aleksandra Djuran.
      Introduction: Colorectal cancer is the major diagnostic and therapeutic problem. The number of patients in the world has increased recently. In our country it is detected late and patients visit doctor in the advanced stage of the disease with already developed metastases. Material and methods: A clinical study was conducted at the Clinic of gastroenterohepatologists, Clinical Center of Sarajevo University on 164 patients. Special attention was given to the symptoms, which are considered to be a macroscopically visible as bleeding, anemia pain, weight loss and disturbance of defecation. Smoking had no effect because a small number of observed patients smoked. Endoscopic examination revealed localization of the tumor in the colon and then underwent targeted biopsy, histological analysis by pathologist, and we determined the concentration of CEA and CA19-9 in the serum. Results: In order to get the most relevant results we used larger data set. The program used to prepare the data was Microsoft Excel 2013, and for the creation of decision trees is a used software RapidMiner version 5. Our research has shown that patients older than 55 years with significant stenosis, metastasis and diarrhea that lasted longer than 3.5 months and bleeding that lasted up to 10 months had cancer of the rectum. Bleeding that lasts longer than 10 months indicated that it was the case of cancer that was localized in the rectum in men and sigma in women. Patients older than 82.5 years and had diarrhea up to 3.5 months developed cancer in the sigma part of the colon. Analyzing pain as a symptom of an alarm, the study found that pain that lasts longer than a few days, is caused by rectal cancer, and occurs after the age of 70.5 years, and in patients younger than 63 years anemia as a alarm symptom, which lasted more than two months in men was caused by cancer of the rectum and in women cancer in other localizations within colon. In patients without stenosis developed bleeding as the most important symptom. We can say that after the age of 74 years cancer of the rectum and sigmoid is more common in men and in women dominate sigma and other locations in the colon. In patients under the 70 years of age with short time of bleeding, cancer predominates in rectum. In patients younger than 63 years can be concluded that weight loss is greater than 8 kg follows rectal cancer. In patients with bleeding that lasted one month or more as classifier occurring the age and gender. Patients younger than 74 years have rectal cancer, while older than 73 years have cancer at other sites. In women these locations are sigma and rectum. Conclusion: Based on this study we can conclude that regardless of the technical advances in medicine must pay special attention to the symptoms that doctors will refer to the localization of the tumor, stenosis of the intestine and possibly metastasis.

      PubDate: Mon, 17 Mar 2014 12:03:11 GMT
  • Use of Quantitative Fluorescent Polymerase Chain Reaction (QF PCR) in
           Prenatal Diagnostic of Fetal Aneuploidies in a 17 Month Period in Parallel
           with Karyotyping

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Rijad Konjhodzic, Edina Dervovic, Ilvana Kurtovic-Basic, Meliha Stomornjak-Vukadin, Adis Muhic, Sumeja Baljevic, Aida Pirnat-Gegic, Ejub Basic, Nurija Bilalovic.
      Introduction: QF PCR has recently entered diagnostic practice as a possible way to bypass culturing of the fetal cells, as well as to provide a rapid response following amniocentesis. Material and methods: The effective value of the QF PCR remains a much debated issue, positions ranging from that it makes classic kayotyping obsolete except in special occasions, to that it is no more than a guideline for a mandatory karyotype. Current practices of the gynecology specialists generates samples in such fashion that kariotyping of samples quickly falls behind to the point of obsoleteness, because, by the time a karyotype has been finished, a window of opportunity for termination of pregnancy has closed. Results: QF PCR provides a rapid response alternative, but it is necessary to establish its reproducibility, as well as an algorithm of its use along classic kariotyping. This study contains samples processed in a period from August 1, 2012 to December 31 2013 in both QF PCR and classic karyotype. Object of this study was compare results obtained by two methods, and establish confidence interval of the QF PCR testing. Overall, 661 amniotic fluid samples were processed and typed with QF PCR, out of which 221 were done in parallel with karyiotyping, as an confirmation of results.

      PubDate: Mon, 17 Mar 2014 11:59:48 GMT
  • Review of the Journal Acta Informatica Medica in 2013

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.

      PubDate: Mon, 17 Mar 2014 11:57:50 GMT
  • A Short Factography About IMIA and EFMI

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jacob Hofdijk, Patrick Weber, John Mantas, George Mihalas, Izet Masic.
      International Medical Informatics Association (IMIA) and European Federation of Medical Informatics are scientific associations which represents Health/Medical informatics as scientific and profesional disciplines. Those associations have long tradition in spreading knowledge, experiences and strategies in organization, practical applications and education within Health, Medical and Biomedical informatics in approximately 60 countries the world. In this review we present basic facts about IMIA and EFMI.who celebrate this 50 years of their establishing as professional associations.

      PubDate: Sat, 25 Jan 2014 11:25:07 GMT
  • The 50th Anniversary IMIA History of Medical Informatics Project

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Casimir A. Kulikowski.
      At the meeting of the IMIA Board in 2009 in Hiroshima, it approved an IMIA 50th Anniversary History Project to produce a historical volume and other materials to commemorate the anniversary of the foundation of the predecessor of IMIA–the IFIP-TC4 in 1967. A Taskforce was organized under the direction of Casimir Kulikowski, then the VP for Services of IMIA, and since that time it has met regularly to plan and implement the 50th Anniversary History of IMIA as an edited volume, and as material available online on a Media Presentation Database. The IMIA Taskforce is gathering IMIA-related archival materials, currently accessible through a prototype media repository at Rutgers University in order to help those contributing to the book or writing their own recollections and histories. The materials will support a chronicle of the development and evolution of IMIA, its contributors, its sponsored events and publications, educational and other professional activities. During 2013 Workshops were held at the Prague EFMI-STC meeting in April and at the MEDINFO 2013 Congress in Copenhagen in August.

      PubDate: Sat, 25 Jan 2014 11:16:52 GMT
  • A Short History of Medical Informatics in Bosnia and Herzegovina

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.
      The health informatics profession in Bosnia and Herzegovina has relatively long history. Thirty five years from the introduction of the first automatic manipulation of data, thirty years from the establishment of Society for Medical Informatics BiH, twenty years from the establishment of the Scientific journal „Acta Informatica Medica (Acta Inform Med“, indexed in PubMed, PubMed Central Scopus, Embase, etc.), twenty years on from the establishment of the first Cathedra for Medical Informatics on Biomedical Faculties in Bosnia and Herzegovina, ten years on from the introduction of the method of “Distance learning” in medical curriculum. The author of this article is eager to mark the importance of the above mentioned Anniversaries in the development of Health informatics in Bosnia and Herzegovina and have attempted, very briefly, to present the most significant events and persons with essential roles throughout this period.

      PubDate: Sat, 25 Jan 2014 11:15:29 GMT
  • Medical Informatics in Croatia – a Historical Survey

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Gjuro Dezelic, Josipa Kern, Mladen Petrovecki, Vesna Ilakovac, Mira Hercigonja-Szekeres.
      A historical survey of medical informatics (MI) in Croatia is presented from the beginnings in the late sixties of the 20th century to the present time. Described are MI projects, applications in clinical medicine and public health, start and development of MI research and education, beginnings of international cooperation, establishment of the Croatian Society for MI and its membership to EFMI and IMIA. The current status of computerization of the Croatian healthcare system is sketched as well as the present graduate and postgraduate study MI curricula. The information contained in the paper shows that MI in Croatia developed and still develops along with its advancement elsewhere..

      PubDate: Sat, 25 Jan 2014 11:13:38 GMT
  • Five Periods in Development of Medical Informatics

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.
      Medical informatics, as scientific discipline, has to do with all aspects of understanding and promoting the effective organization, analysis, management, and use of information in health care. While the field of Medical informatics shares the general scope of these interests with some other health care specialities and disciplines, Medical (Health) informatics has developed its own areas of emphasis and approaches that have set it apart from other disciplines and specialities. For the last fifties of 20th century and some more years of 21st century, Medical informatics had the five time periods of characteristic development. In this paper author shortly described main scientific innovations and inventors who created development of Medical informatics.

      PubDate: Sat, 25 Jan 2014 11:12:15 GMT
  • Evolution of Trends in European Medical Informatics

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      George I. Mihalas.
      This presentation attempts to analyze the trends in Medical Informatics along half a century, in the European socio-political and technological development context. Based on the major characteristics which seem dominant in some periods, a staging is proposed, with a description of each period – the context, major ideas, views and events. A summary of major features of each period is also added. This paper has an original presentation of the evolution of major trends in medical informatics.

      PubDate: Sat, 25 Jan 2014 11:10:41 GMT
  • An Abridged History of Medical Informatics Education in Europe

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Arie Hasman, John Mantas, Tatyana Zarubina.
      This contribution presents the development of medical informatics education in Europe. It does not discuss all developments that took place. Rather it discerns several themes that indicate the progress in the field, starting from the initiation phase to the final quality control phase. .

      PubDate: Sat, 25 Jan 2014 11:08:11 GMT
  • Reflections On the Development of Medical Informatics

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Barry Barber, Maureen Scholes.
      The recording of numbers appears to pre-date the emergence of writing and excavations of the clay tablets of civilisations in the Middle East have shown that clay tablets were used to keep account of activities undertaken in a systematic fashion. Correspondingly, various forms of abacus have been used types of calculation from the Sumerian abacus dating from about 4 ½ thousand years ago to the Chinese abacus (Suanpan) from around 2 thousand years ago. As time passed various forms of writing were developed using animal hides, which were developed as vellum and papyrus which eventually developed into paper. Wood block printing, also, was a very ancient art and movable type printing had been utilised in the far East but the development of movable type page setting in Europe transformed the process of printing.

      PubDate: Sat, 25 Jan 2014 11:03:18 GMT
  • The Early History of European Federation of Medical Informatics

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hans E. Peterson.
      The story of the European Federation of Medical Informatics (EFMI) can be looked upon as one of the followers from the early days of the development of Societies and federations for persons interested in Information Technology and in cooperation and exchange of information and technology, not only in countries but also between countries.

      PubDate: Sat, 25 Jan 2014 11:00:05 GMT
  • About the Beginnings of Medical Informatics in Europe

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Francis Roger France.
      The term “Informatics” was created in 1962 from two words, information and automatic, and covers all techniques, information concepts and applications of computers. Among them, medicine is the field where we will describe some factors of development in Europe since the late sixties. It took some time for obtaining the acceptance of this new terminology worldwide, but today medical informatics is a well defined discipline which had a tremendous development last decades. This paper tries to recall the context and events from the beginning of medical informatics in Europe.

      PubDate: Sat, 25 Jan 2014 10:57:33 GMT
  • History of Medical Informatics in Europe - a Short Review by Different

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      George Mihalas, Jana Zvarova, Casimir Kulikowski, Marion Ball, Jan van Bemmel, Arie Hasman, Izet Masic, Diane Whitehouse, Barry Barber.
      The panel intended to collect data, opinions and views for a systematic and multiaxial approach for a comprehensive presentation of “History of Medical Informatics”, treating both general (global) characteristics, but emphasizing the particular features for Europe. The topic was not only a subject of large interest but also of great importance in preparing a detailed material for celebration of forty years of medical informatics in Europe. The panel comprised a list of topics, trying to cover all major aspects to be discussed. Proposals of staging the major periods of medical informatics history were also discussed.

      PubDate: Sat, 25 Jan 2014 10:56:16 GMT
  • Special Tribute on Morris F. Collen: Charismatic Leader of Medical

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Marion Ball, Donald Lindberg, Izet Masic.
      This editorial is dedicated in honor of Morris F. Collen, MD, a pioneer in the field of medical informatics. During his remarkable career, Dr. Collen’s has made many important contributions not only to the field of medical informatics, but also to the public health and the creation of new models of payment and prevention. His endeavors and ideas found fertile ground and left a mark not only in the national, but also in the international setting.

      PubDate: Sat, 25 Jan 2014 10:54:36 GMT
  • As Well as Proper Citation, References in Biomedical Articles Should Be

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Robert Siebers.

      PubDate: Wed, 04 Dec 2013 10:34:24 GMT
  • Atrioventricular Septal Defect with Common Atrioventricular Junction
           Guarded by a Common Valve Consisting of Left Atrioventricular Trifoliate

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Xhevdet Krasniqi, Masar Gashi, Blerim Berisha, Ejup Pllana, Aurora Bakalli, Flora Abazi, Dardan Koçinaj.
      Introduction. Atrioventricular septal defect with common atrioventricular junction is a rare adult congenital cardiac syndrome. This occurrence with prolonged survival is exceptionally rare. Case report. We present the case of a patient who presented with this defect with common atrioventricular junction who survived to the age of 32. We describe a 32-year-old man with atrioventricular septal defect with common atrioventricular junction guarded by a common valve. His history, clinical course, and anatomic findings are discussed along with the factors which may have contributed to his longevity, which is unique in the medical literature. His management reflected the state of medical knowledge at the time when he presented, and although alternate approaches may have been utilized if the patient presented today. We discuss the findings, frequency, classification, and management of congenital defects. Development of embryonic structure is altered by interaction between genetics and environmental factors toward a rare associated of congenital cardiac defects-complex congenital heart disease. Conclusion. This case demonstrates that patients with very complex congenital cardiac disease may survive to adulthood, presenting challenges in both medical and surgical treatment.

      PubDate: Wed, 04 Dec 2013 10:33:27 GMT
  • Open Data Sharing in the Context of Bioresources

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Paola DeCastro, Alessia Calzolari, Federica Napolitani, Anna Maria Rossi, Laurence Mabile, Anne Cambon-Thomsen, Elena Bravo.
      Recently many international initiatives have been developed to improve access to scientific information and to promote open data sharing. In the complex field of bioresources, the BRIF (Bioresource Research Impact Factor) project aims to create suitable methods to recognise and measure the use and impact of biological resources in scientific/academic work, in order to maximize access by researchers to collections of biological materials and attached databases, and to recognize efforts involved in their maintenance. The lack of a proper recognition of scientific contribution is in fact a major obstacle which impedes bioresource sharing. In this context, the BRIF initiative can be considered as a tool to facilitate research resource sharing,

      PubDate: Wed, 04 Dec 2013 10:17:19 GMT
  • Trends in Authorship in an Indian Pediatric Dentistry Journal: Relevance
           of Matthew Effect

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Jatinder Kaur Dhillon, Gauri Kalra, Ashutosh Sharma, Vijay Prakash Mathur.
      Introduction: The maxim “rich get richer and the poor get poorer” forms the basis for Matthew effect in Science. Our goal of conducting this study was to test the hypothesis that the gap in number of publications between renowned, older authors and newer authors amongst Indian pediatric dentists widens over time as stated by the Matthew effect and possible trends in publication in Journal of Indian Society of Pedodontics & Preventive Dentistry (JISPPD). Materials and methods: It was hypothesized that the Matthew effect is applicable to the work published by Indian Pedodontists in the official publication of Indian Society of Pedodontics & Preventive Dentistry (ISPPD). The names of the authors in JISPPD from 1996 to 2011 were recorded year wise and the data was entered in Microsoft excel 2007 and analyzed using SPSS software. Results: The study revealed that there were a total of 823 papers published in JISPPD during the study period (1996 to 2011) by 1142 authors. 71.6% authors had contributed only one paper and 14.4% authors had contributed two papers during the study period. Only 0.6% authors had contributed to 20 or more papers. The results revealed evidence of Matthew effect for publications in JISPPD and the effect is relatively large. Conclusions: The results of the study showed that the Matthew effect is prevalent in the publication trends in JISPPD.

      PubDate: Wed, 04 Dec 2013 10:15:36 GMT
  • Forearm Approach for Percutaneous Coronary Procedures

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Zoran Stajic, Radoslav Romanovic, Dragan Tavciovski.
      This article gives contemporary review on the forearm approach for percutaneous diagnostic and interventional coronary procedures. Advantages and disadvantages as well as practical issues and current controversies regarding both radial and ulnar artery approach are discussed throughout the paper. Having in mind advantages of forearm approach in terms of safety and comfort over the traditional femoral approach, as well as the rapid development of invasive technology in the past years, it will probably become the default vascular approach for all percutaneous coronary procedures in the near future.

      PubDate: Wed, 04 Dec 2013 10:13:05 GMT
  • Computerized Tomography of Thoracic Pathologies in the Pediatric Age
           Group: Pictorial Essay

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Aysegul Solmaz-Tuncer, Safiye Gurel, Kamil Gurel, Ahmet Ozbag, Ayten Pamukcu, Zeliha Cosgun.
      Aim of the study. The purpose of this study is to illustrate the imaging findings of the lung parenchyma and the thoracic wall pathologies in pediatric age group using Standard (CT) and High-Resolution Computed Tomography (HRCT). Results and discussion. We discuss and illustrate the following: Pleural hematoma, Pulmonary Contusion, Histiocytosis X, Tuberculosis, Right sided arcus aortae, Pectus excavatum, Operated Pectus excavatum, Morgagni hernia, Pleurisy, Right middle lobe syndrome, Pneumonia, Hydatid Cyst, Takayasu arteritis, Kartagener syndrome, Bronchiectasis, Bronchiolitis obliterans organizing pneumonia, and Osteomyelitis. We also discuss the diagnosis clues.

      PubDate: Wed, 04 Dec 2013 10:11:18 GMT
  • Assessment of Osteoporosis in Family Medicine Obtained by Ultrasound

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Esad Alibasic, Enisa Ramic, Olivera Batic Mujanovic, Enes Avdibasic, Damir Husic, Alma Alic.
      Introduction: Osteoporosis is a disease characterized by a decrease in bone mineral density, making bones become less rigid, and therefore susceptible to fractures, either spontaneously or with force, which is lower than otherwise needed for healthy bones fractured. Nearly 10% of the world population and 30% of women after menopause, suffer from osteoporosis. Clinical assessment of osteoporosis in family medicine is key to prevention, early detection and treatment of osteoporosis. Objective: To investigate the possibility of early detection and diagnosis of osteoporosis by analyzing the risk factors for osteoporosis and to compare the results with the parameters obtained by ultrasound densitometry of calcaneus, and determine the relationship of calcaneus densitometry with DXA findings, as the gold standard for the diagnosis of osteoporosis. Patients and methods: The study included all patients of Family Medicine Kalesija Team 1, aged 50 years and over, a total of 711 patients, of whom 425 were women and 286 men. In all patients we assessed the existence of the following risk factors for osteoporosis: Constitutional: gender, age, weight, constitution, menarche and menopause, loss of height and stooped posture; Living habits: smoking, alcohol consumption, coffee, physical activity, and medications: long-term use corticosteroids, anticonvulsants, antacids, thyroid hormones. Comorbidity: history of fractures, hyperthyroidism, COPD, Chussing’s disease, diabetes. In the group of high-risk patients determined by the clinical assessment, quantitative ultrasound densitometry screening was carried out. Monitoring parameters derived with densitometry: the value of T-score, BUA (Broadband Ultrasound Attenuation), SOS (Speed ​​of Sound), QUI (Quantitative Ultrasound Index). To confirm the diagnosis of osteoporosis, in all patients with positive findings using ultrasound densitometry (T score lower than 2.5), another densitometry was performed by standard DXA method. Results: The incidence of osteoporosis was 96% in women and 4% in men. Differences in prevalence between men and women are statistically significant. People with and without osteoporosis significantly differ in gender, age, weight, constitution (BMI-Body Mass Index). The parameters that distinguish those with and without osteoporosis: age, weight, height, BMI, gender. Out of the total of 711 patients, in 11% of patients the clinical evaluation showed the existence of high risk of osteoporosis. In 9.8% patients, the values ​​were determined by ultrasound densitometry, where T score was lower than 2.5 what induces a high risk of fractures, and for 8.8% patients the DXA confirmed the diagnosis of osteoporosis. Conclusion: Clinical assessment of osteoporosis in the family medicine clinic performed in timely and focused history of risk factors for osteoporosis, with additional findings from quantitative densitometry of calcaneus, was sufficient for the early detection and screening of patients with high risk for osteoporosis. With good clinical assessment of osteoporosis it will be necessary to send all patients who enter the high-risk group to undergo ultrasound densitometry of calcaneus, to make it possible to determine the risk of bone fractures and osteoporosis in time, and then refer patients for further processing and DXA measurements according to the guidelines by the WHO.

      PubDate: Wed, 04 Dec 2013 10:01:43 GMT
  • Early Amniocentesis as a Method of Choice in Diagnosing Gynecological

    • Abstract: Publication year: 2013
      Source:Acta Informatica Medica
      Sebija Izetbegovic, Senad Mehmedbasic.
      Introduction: The aim of prenatal diagnosis is to detect fetal structural and genetic abnormalities. Used are different medical methods, procedures, processes and techniques. For this reason we can speak about the prevention and detection of hereditary diseases and congenital anomalies in the unborn fetus. Material and methods: The authors analyzed the results of early amniocentesis tests performed during 2009 in Institute for Gynecology, Infertility and Perinatology “Mehmedbasic” in Sarajevo. Performed is 299 analysis of amniotic fluid after amnion puncture done in the Institute or at the Clinic of Gynecology and Obstetrics (GAK) Sarajevo. Results and Discussion: Indications for the performance of early amniocentesis were: age greater over 35 (84.9%), positive ultrasound markers (1.6%), positive biochemical markers (5.6%) and positive family history for hereditary diseases (7.9%). Detected was 19 pathological cariograms or very high 7% of the total annual number of amniocentesis. An analysis of the distribution of pregnant women in relation to the indication of the result of cytogenetic analysis for each table made ​​positive predictive value (PPV). For indicator age PPV was 0.11, 0.66 for ultrasound markers, for biochemical markers 0.13, for other indications–0.04. The logistic regression model (odds -ratio 11.234 ) indicate a positive ultrasound findings in relation to the year indicates that the risk to gain abnormal fetal karyotype 13 times higher when using only age as an indication for early amniocentesis. Of the 19 pathological cariogram largest number refers to M.Down (10), Sy. Edwards was detected in 2 patients, Sy. Klinefelter in 3, mosaicism in 3 and translocation gene in two of the fetus. Conclusion: The authors would like to acknowledge a very high percentage of pathological cariogram risk groups, the extension of indications for RAC indicate the value of ultrasound markers as a good screening methods and the need for social incentives to perform screening tests and early amniocentesis in B&H in order to prevent genetic abnormalities.

      PubDate: Wed, 04 Dec 2013 09:59:51 GMT
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