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Journal Cover Acta Informatica Medica
  [SJR: 0.217]   [H-I: 4]   [0 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
   Published by ScopeMed Homepage  [97 journals]
  • The Most Influential Scientist in the Development of Medical informatics
           (10): Marsden S. Blois

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Tue, 02 Feb 2016 05:45:28 GMT
       
  • Foramen Magnum Meningioma: a Case Report and Review of Literature

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Pavao Jurinovic, Ana Repic Bulicic, Marino Marcic, Nikolina Ivica Mise, Marina Titlic, Enra Suljic.
      Introduction: Meningiomas are slow-growing benign tumors that arise at any location where arachnoid cells reside. Although meningiomas account for a sizable proportion of all primary intracranial neoplasms (14.3–19%), only 1.8 to 3.2% arise at the foramen magnum. Their indolent development at the craniocervical junction makes clinical diagnosis complex and often leads to a long interval between onset of symptoms and diagnosis. Case report: We report a case of a 79-year-old male patient, presented with ataxia and sense of threatening fainting during verticalization. Magnetic resonance imaging revealed the presence of meningioma in the right side of craniospinal junction.

      PubDate: Tue, 02 Feb 2016 05:36:15 GMT
       
  • Successful Evaluation of Biphasic T-wave of Wellens Syndrome in the
           Emergency Department

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Ali Attila Aydin, Kemal Türker Ulutas, Cemile Aydin, Murtaza Kaya, Umut Akar, Tayfun Ture.
      Introduction: Wellens Syndrome (WS) is a condition characterized by typical changes in ECG, which are biphasic T-wave inversions (less common) or symmetric and deeply inverted T waves (including 75%) in lead V2–V3 chest derivations. WS is considered important because it has not only diagnostic value but also prognostic value. Case report: A 52-year-old male patient without cardiovascular disease or risk factors was admitted to the emergency department (ED) suffering with chest pain and syncope, just after having been involved in a discussion at work. Chest pain was radiating to the left arm and was not precipitated by exertion. Shortness of breath was not accompanied by angina. The patient underwent cardiac catheterization at Department of Cardiology. Stents were positioned in both LADA and a severe lesion in the left main coronary artery. The patient was discharged two days following catheterization, due to no chest pain and hemodynamic instability during the hospitalization. The patient has approved the inform consent for to be used for this case report.

      PubDate: Tue, 02 Feb 2016 05:34:00 GMT
       
  • Laparoscopic Management of Adhesive Small Bowel Obstruction

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Ferid Konjic, Enes Idrizovic, Ismar Hasukic, Alen Jahic.
      Introduction: Adhesions are the reason for bowel obstruction in 80% of the cases. In well selected patients the adhesive ileus laparoscopic treatment has multiple advantages which include the shorter hospitalization period, earlier food taking, and less postoperative morbidity rate. Case report: Here we have a patient in the age of 35 hospitalized at the clinic due to occlusive symptoms. Two years before an opened appendectomy had been performed on him. He underwent the treatment of exploration laparoscopy and laparoscopic adhesiolysis. Dilated small bowel loops connected with the anterior abdominal wall in the ileocecal region by adhesions were found intraoperatively and then resected harmonically with scalpel. One strangulation around which a small bowel loop was wrapped around was found and dissected. Postoperative course was normal.

      PubDate: Tue, 02 Feb 2016 05:32:16 GMT
       
  • Social and Psychological Effects of the Internet Use

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Marianna Diomidous, Kostis Chardalias, Adrianna Magita, Panagiotis Koutonias, Paraskevi Panagiotopoulou, John Mantas.
      Background and Aims: Over the past two decades there was an upsurge of the use of Internet in human life. With this continuous development, Internet users are able to communicate with any part of the globe, to shop online, to use it as a mean of education, to work remotely and to conduct financial transactions. Unfortunately, this rapid development of the Internet has a detrimental impact in our life, which leads to various phenomena such as cyber bullying, cyber porn, cyber suicide, Internet addiction, social isolation, cyber racism etc. The main purpose of this paper is to record and analyze all these social and psychological effects that appears to users due to the extensive use of the Internet. Materials and Methods: This review study was a thorough search of bibliography data conducted through Internet and library research studies. Key words were extracted from search engines and data bases including Google, Yahoo, Scholar Google, PubMed. Findings: The findings of this study showed that the Internet offers a quick access to information and facilitates communication however; it is quite dangerous, especially for young users. For this reason, users should be aware of it and face critically any information that is handed from the website

      PubDate: Tue, 02 Feb 2016 04:32:55 GMT
       
  • ELISA Test for Analyzing of Incidence of Type 1 Diabetes Autoantibodies
           (GAD and IA2) in Children and Adolescents

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Marina Delic-Sarac, Selma Mutevelic, Jasenko Karamehic, Salih Saracevic, Djemo Subasic, Tomislav Jukic, Jozo Coric, Ognjen Ridjic, Mirsad Panjeta, Lejla Zunic.
      Introduction: Anti GAD (antibodies on glutamic acid decarboxylase) and anti-IA2 antibodies (against tyrosine phosphatase ), today, have their place and importance in diagnosis and prognosis of Type 1 diabetes. Huge number of patients with diabetes mellitus type 1 have these antibodies. Insulin antibodies are of critical importance in diagnosis of diabetes mellitus type 1 for pediatric population. Materials and methods: During 2014, the samples of 80 patients from Clinical Center University Sarajevo (CCUS) Pediatrics clinic’s, Endocrinology department were analyzed on anti-GAD and IA2 antibodies. The samples of serums of all patients were analyzed with ELISA tests using Anti GAD ELISA (IgG) kites from EUROIMMUN company. These are quantitative in vitro tests for human antibodies against decarboxylase of glutamine acid (GAD) and IA2, in serum or EDTA plasm. Results: During the period of one year, in CCUS’s Organizational unit, Institute for Clinical Immunology, 80 samples of patients with anti GAD and IA2 antibodies were analyzed. Out of total number of samples, 41 were male patients, or 51% and 39 female, or 49%. The youngest patient was born in 2012, and the oldest in 1993. Age average was represented by the patients born in 2001. Share of positive results for IA2 antibodies and GAD antibodies was 37% for IA2 antibodies, and 63% for GAD antibodies. Discussion: During an autoimmune – mediated Diabetes mellitus type 1 leads to T-cell mediated destruction of beta cells of pancreatic islets, reduced production of insulin and glucose metabolism. Studies have shown that these bodies are the most intense single marker for identifying persons with increased risk for diabetes development.

      PubDate: Tue, 02 Feb 2016 04:29:37 GMT
       
  • Comparative Investigation of Health Literacy Level of Cardiovascular
           Patients Hospitalized in Private and Educational Hospitals of Kerman City,
           Iran

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Sajedeh Malekzadeh, Mohammad Azami, Moghadameh Mirzaei, Fatemeh Motamedi.
      Introduction: literacy involves a complex set of abilities to understand and use symbolic systems of a culture for personal development and social development in a diverse set of skills required as an adult to exercise behavior are considered in society. Objectives: The aim of this study was to evaluate Comparative investigation of health literacy level of cardiovascular patients hospitalized in private and public educational hospitals of Kerman city. Methods: This study used survey methods, analytical and cross-sectional manner. Data was collected through questionnaires distributed among 200 patients of cardiovascular-hospitalization took place in the city of Kerman. To analyze the data in the description of the mean, standard deviation and frequency distribution tables and the level of analysis to determine the relationship between gender and marital status of health literacy test or nonparametric test Mann-Whitney T-Test and, for the relationship between group employment and residence, a one-way analysis of variance or Kruskal-Wallis test, to evaluate the relationship between age and income, Pearson and Spearman correlation to investigate the relationship between level of education and health literacy of SPPS software version 21 was used. Results: The results showed that 10% of patients at educational hospitals in Kerman adequate health literacy, and 48% of patients in private hospitals had adequate health literacy. As a result, there is a significant difference of health literacy between the two types of hospital (p-value

      PubDate: Tue, 02 Feb 2016 04:25:53 GMT
       
  • Factors Affecting Successful Implementation of Hospital Information
           Systems

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Mehrdad Farzandipur, Fatemeh Rangraz jeddi, Esmaeil Azimi.
      Background: Today, the use of information systems in health environments, like any other fields,is necessary and organizational managers are convinced to use these systems. However, managers’ satisfaction is not the only factor in successfully implementing these systems and failed information technology projects (IT) are reported despite the consent of the directors. Therefore, this study aims to determine the factors affecting the successful implementation of a hospital information system. Methods: The study was carried out as a descriptive method in 20 clinical hospitals that the hospital information system (HIS) was conducted in them. The clinical and paraclinical users of mentioned hospitals are the study group. 400 people were chosen as samples in scientific method and the data was collected using a questionnaire consisted of three main human, managerial and organizational, and technological factors, by questionnaire and interview. Then the data was scored in Likert scale (score of 1 to 5) and were analyzed using the SPSS software. Results: About 75 percent of the population were female, with average work experience of 10 years and the mean age was 30 years. The human factors affecting the success of hospital information system implementation achieved the mean score of 3.5, both organizational and managerial factors 2.9 and technological factors the mean of 3. Conclusion: Human factors including computer skills, perceiving usefulness and perceiving the ease of a hospital information system use are more effective on the acceptance and successful implementation of hospital information systems; then the technological factors play a greater role. It is recommended that for the successful implementation of hospital information systems, most of these factors to be considered

      PubDate: Tue, 02 Feb 2016 04:24:29 GMT
       
  • Health Information Security in Hospitals: the Application of Security
           Safeguards

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Esmaeil Mehraeen, Haleh Ayatollahi, Maryam Ahmadi.
      Introduction: A hospital information system has potentials to improve the accessibility of clinical information and the quality of health care. However, the use of this system has resulted in new challenges, such as concerns over health information security. This paper aims to assess the status of information security in terms of administrative, technical and physical safeguards in the university hospitals. Methods: This was a survey study in which the participants were information technology (IT) managers (n=36) who worked in the hospitals affiliated to the top ranked medical universities (university A and university B). Data were collected using a questionnaire. The content validity of the questionnaire was examined by the experts and the reliability of the questionnaire was determined using Cronbach’s coefficient alpha (α=0.75). Results: The results showed that the administrative safeguards were arranged at a medium level. In terms of the technical safeguards and the physical safeguards, the IT managers rated them at a strong level. Conclusion: According to the results, among three types of security safeguards, the administrative safeguards were assessed at the medium level. To improve it, developing security policies, implementing access control models and training users are recommended.

      PubDate: Tue, 02 Feb 2016 04:23:06 GMT
       
  • Evaluating Usability of Radiology Information Systems in Hospitals of
           Tabriz University of Medical Sciences

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Peyman Rezaei-Hachesu, Esmaeil Pesianian, Mohsen Mohammadian.
      Introduction and purpose: Radiology information system (RIS) in order to reduce workload and improve the quality of services must be well-designed. Heuristic evaluation is one of the methods that understand usability problems with the least time, cost and resources. The aim of present study is to evaluate the usability of RISs in hospitals. Research Method: This is a cross-sectional descriptive study (2015) that uses heuristic evaluation method to evaluate the usability of RIS used in 3 hospitals of Tabriz city. The data are collected using a standard checklist based on 13 principles of Nielsen Heuristic evaluation method. Usability of RISs was investigated based on the number of components observed from Nielsen principles and problems of usability based on the number of non-observed components as well as non-existent or unrecognizable components. Results: by evaluation of RISs in each of the hospitals 1, 2 and 3, total numbers of observed components were obtained as 173, 202 and 196, respectively. It was concluded that the usability of RISs in the studied population, on average and with observing 190 components of the 291 components related to the 13 principles of Nielsen is 65.41 %. Furthermore, problems of usability were obtained as 26.35%. Discussion and Conclusion: The established and visible nature of some components such as response time of application, visual feedbacks, colors, view and design and arrangement of software objects cause more attention to these components as principal components in designing UI software. Also, incorrect analysis before system design leads to a lack of attention to secondary needs like Help software and security issues.

      PubDate: Tue, 02 Feb 2016 04:19:41 GMT
       
  • Comparing Smoothing Techniques for Fitting the Nonlinear Effect of
           Covariate in Cox Models

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Daem Roshani, Ebrahim Ghaderi.
      Background and Objective: Cox model is a popular model in survival analysis, which assumes linearity of the covariate on the log hazard function, While continuous covariates can affect the hazard through more complicated nonlinear functional forms and therefore, Cox models with continuous covariates are prone to misspecification due to not fitting the correct functional form for continuous covariates. In this study, a smooth nonlinear covariate effect would be approximated by different spline functions. Material and Methods: We applied three flexible nonparametric smoothing techniques for nonlinear covariate effect in the Cox models: penalized splines, restricted cubic splines and natural splines. Akaike information criterion (AIC) and degrees of freedom were used to smoothing parameter selection in penalized splines model. The ability of nonparametric methods was evaluated to recover the true functional form of linear, quadratic and nonlinear functions, using different simulated sample sizes. Data analysis was carried out using R 2.11.0 software and significant levels were considered 0.05. Results: Based on AIC, the penalized spline method had consistently lower mean square error compared to others to selection of smoothed parameter. The same result was obtained with real data. Conclusion: Penalized spline smoothing method, with AIC to smoothing parameter selection, was more accurate in evaluate of relation between covariate and log hazard function than other methods.

      PubDate: Tue, 02 Feb 2016 04:17:05 GMT
       
  • Developing a Fuzzy Expert System to Predict the Risk of Neonatal Death

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Reza Safdari, Maliheh Kadivar, Mostafa Langarizadeh, Ahmadreaza Farzaneh Nejad, Farzaneh Kermani.
      Introduction: This study aims at developing a fuzzy expert system to predict the possibility of neonatal death. Materials and Methods: A questionnaire was given to Iranian neonatologists and the more important factors were identified based on their answers. Then, a computing model was designed considering the fuzziness of variables having the highest neonatal mortality risk. The inference engine used was Mamdani’s method and the output was the risk of neonatal death given as a percentage. To validate the designed system, neonates’ medical records real data at a Tehran hospital were used. MATLAB software was applied to build the model, and user interface was developed by C# programming in Visual Studio platform as bilingual (English and Farsi user interface). Results: According to the results, the accuracy, sensitivity, and specificity of the model were 90%, 83% and 97%, respectively. Conclusion: The designed fuzzy expert system for neonatal death prediction showed good accuracy as well as proper specificity, and could be utilized in general hospitals as a clinical decision support tool.

      PubDate: Tue, 02 Feb 2016 04:15:08 GMT
       
  • The Diagnostic Value of Skin Disease Diagnosis Expert System

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Fatemeh Rangraz Jeddi, Masoud Arabfard, Zahra Arbkermany, Hamidreza Gilasi.
      Background: Evaluation is a necessary measure to ensure the effectiveness and efficiency of all systems, including expert systems. The aim of this study was to determine the diagnostic value of expert system for diagnosis of complex skin diseases. Methods: A case-control study was conducted in 2015 to determine the diagnostic value of an expert system. The study population included patients who were referred to Razi Specialized Hospital, affiliated to Tehran University of Medical Sciences. The control group was selected from patients without the selected skin diseases. Data collection tool was a checklist of clinical signs of diseases including pemphigus vulgaris, lichen planus, basal cell carcinoma, melanoma, and scabies. The sample size formula estimated 400 patients with skin diseases selected by experts and 200 patients without the selected skin diseases. Patient selection was undertaken with randomized stratified sampling and their sign and symptoms were logged into the system. Physician’s diagnosis was determined as the gold standard and was compared with the diagnosis of expert system by SPSS software version 16 and STATA. Kappa statistics, indicators of sensitivity, specificity, accuracy and confidence intervals were calculated for each disease. An accuracy of 90% was considered appropriate. Results: Comparing the results of expert system and physician’s diagnosis at the evaluation stage showed an accuracy of 97.1%, sensitivity of 97.5% and specificity of 96.5% The Kappa test indicated a high agreement of 93.6%. Conclusion: The expert system can diagnose complex skin diseases. Development of such systems is recommended to identify all skin diseases.

      PubDate: Tue, 02 Feb 2016 04:13:13 GMT
       
  • Defining the Modalities of Intravenous Contrast Application During the
           Diagnostics of Hepatic Metastases with Computerized Tomography

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Arben Kutllovci, Halit Ymeri, Drita Zogaj, Skender Kutllovci, Dukagjin Zogaj.
      Introduction: The liver is the biggest human abdominal parenchymal organ; it weights approximately 1500 grams and is located in the right hypochondrium, under the diaphragm. Liver is able to perform multiple functions also by means of the rich dual vascularization: hepatic arterial system and the portal vein system, between which exists a short circuit (shunt) and free mixture inside the sinusoid, whilst the two flows drain in the same vein system. The discovery of CT and its application in practice fundamentally changes the importance of diagnostic methods for hepatobiliary lesions. Patients and methods: During a 4-year period, 984 patients suspected with liver or biliary tract disease were explored with CT. 117 of these patients were analyzed with liver metastases. Examinations of the liver was performed in dorsal decubitus and in absolute apnea with spiral movement of the table and in denominations of 1and 5 mm. Siemens MSCT 64 and 6 tier apparatuses enable short scanning time with almost immediate reconstruction, which offers all the necessary elements required for carrying out certain protocols. Results: The average density of metastatic lesions is about 20 HU smaller than normal liver parenchyma. Metastasis with necrosis are more hypodense (30-50 HU smaller than normal liver parenchyma), whilst necrotic metastases with smaller dimensions are almost isodense with normal parenchyma. However, metastases with diameter between 4 to 6 cm are completely isodense and will remain so even after the application of I.V. contrast. The average more frequent size according to most authors, as well as according to our material (148 patients or 90%) was 2-3 cm in transversal diameter.

      PubDate: Tue, 02 Feb 2016 03:59:04 GMT
       
  • Interventional Radiologists: a Necessary Evaluation of Technical,
           Protective and Technological Operation

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Sayed Ali Rahimi, Maryam Pourkaveh.
      Background and purpose: To present the results of occupational radiation doses investigated through a Hospitals of Mazandaran Medical Science Universities in north of Iran. Radiology unit has an important role in diagnosis of many disorders with providing suitable and high quality pictures. A good picture was provided using correct technical criteria and suitable circumstance of patient. Finally, operation and knowledge of radiology personnel directly has a primary role in determining quality of radiography. Materials and Methods: This study was done in order to determine personnel operation in the units of hospitals radiologist related to University of Mazandaran Medical Science. Data collection tools are made of a researcher check list that was used after obtaining suitable letter and validity indexes. All of the 73 personnel of radiology unit related to Mazandaran Medical Science were studied. 35 operations (in technical, protective and technological fields) of any personnel, in three distinct shifts were observed and recorded. All of them were tested regarding these three fields with a total of 40 questions. Results: The total scores received from personnel in technical part in the morning, evening and night shift were 66.4, 53.9 and 60.2 percent respectively. Received scores from personnel in the protective fields were 68.1, 59.5 and 60.2 percent. Moreover, received scores from personnel in the technological operation fields were 47.8, 39.95 and 43.65 percent respectively. Comparison of these three scores in technical, protective and technological operation fields showed a meaningful difference (p

      PubDate: Tue, 02 Feb 2016 03:57:33 GMT
       
  • Maximum Time of the Effect of Antileukotriene - Zileuton in Treatment of
           Patients with Bronchial Asthma

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Naim Morina, Gëzim Boçari, Ali Iljazi, Kadir Hyseini, Gunay Halac.
      Objective: Maximum time of the effect of antileukotriene substances - Zileuton in the treatment of patients with bronchial asthma and increased bronchial reactivity and of the salbutamol as agonist of the beta2 adrenergic receptor studied in this work. Methods: Parameters of the lung function are determined with Body plethysmography. Raw and ITGV were registered and specific resistance (SRaw) was calculated. Zileuton (Zyflo, tbl.. 600 mg), producer Cornerstone Therapeutics, USA was used in the research. Results: Results of this research, in patients with bronchial asthma, indicate that antileukotriene substances–Zileuton administered in a dose of 600 mg first day (oral route of administration 4 x 1 tbl..) has not caused significant decrease of the specific resistance of the airways (SRaw) (p value 0.1> Alpha 0.05), whereas Zileuton administered two days in a row, in a dose of 600 mg (4 x 1 tbl.. a day), has caused significant decrease of the specific resistance of the airways (SRaw) (P value 0.03 < Alpha 0.05). Effect of the control with salbutamol (beta2-adrenergic receptor agonist) is efficient in the removal of the increased bronchomotor tone, causing significant decrease of the resistance (Raw), respectively of the specific resistance (SRaw), (p value 0.05 = Alpha 0.05). Conclusion: Formation of leukotrienes depends on the lypoxygenation of the arachidonic acid by 5-lypoxygenase. Zileuton is an active and powerful inhibitor of the activity of 5- lypoxygenase and as such inhibits generation of its products. Consequently, besides inhibition of cys-LTs’, zileuton also inhibits the formation of leukotriene B4 (LTB4), which is a powerful chemotactic of other eicosanoids too, which depend on the synthesis of lekotriene A4 (LTA4). This suggests that the effect of antileukotrienes (Zileuton) is not immediate after oral administration, but the powerful effect of the Zileuton seen only after two days of inhibition of cys-LTs’, and inhibition of leukotriene B4 (LTB4) and A4 (LTA4).

      PubDate: Tue, 02 Feb 2016 03:55:58 GMT
       
  • Hepato - Cephalic Index as a Predictor of Intrauterine Growth Restriction

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Ramadan Dacaj, Sebija Izetbegovic, Goran Stojkanovic, Curr Gjocaj.
      Aim: The aims of this study were to compare ultrasound fetoplacental parameters and to calculate Hepato-Cephalic Index (HCI) as a new predictor of IUGR. Methods and material: A clinical prospective study was conducted and included 120 pregnant women divided in two groups: non IUGR group included healthy pregnant women (n=60) and IUGR group included pregnant women with preeclampsia and IUGR (n=60). Outcome measures were following ultrasound fetoplacental parameters in fetuses with IUGR and non IUGR: Fetal Liver Length (FLL), Femur Length (FL), Biparietal Diameter (BPD), Placental Maturation by Grannum, Amniotic Fluid Index (AFI) and Hepato-Cephalic Index (HCI). Sonography was carried out by probe 3.5 Mhz type MINDRAY DC 7. Results: The mean of maternal age was 30.0±6.1 years in women with preeclampsia and IUGR and 28.1±5.1 years in healthy pregnant women, p> 0.05. There was a statistically significant difference in values of: FLL (p < 0.001), FL (p = 0.004), BPD (p < 0.001), AFI (p < 0.001), HCI (p < 0.001) between IUGR and non IUGR groups. The most of women with preeclampsia and IUGR had grade III of placental maturation (48.3%). There is a significant association between the placental maturation and the diagnosis, p < 0.001. There was a statistically significant difference in body mass of newborns between IUGR and non IUGR groups, p < 0.001. Conclusion: In a fetus with IUGR in preeclampsia there is a reduction in FLL, FL, BPD, AFI and HCI and there is a early maturation of the placenta. By measurement of fetoplacental ultrasonic parameters of liver, pregnant women will experience prediction of risk pregnancy (preeclampsia with IUGR) due to hypoxia.

      PubDate: Tue, 02 Feb 2016 03:17:56 GMT
       
  • Scientometric Analysis of the Journals of the Academy of Medical Sciences
           in Bosnia and Herzegovina

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Izet Masic, Edin Begic, Lejla Zunic.
      Introduction: Currently in Bosnia and Herzegovina there are 25 journals in the field of biomedicine, 6 of them are indexed in Medline/PubMed base (Medical Archives, Materia Socio-Medica, Acta Informatica Medica, Acta Medica Academica, Bosnian Journal of Basic Medical Sciences (BJBMS) and Medical Glasnik), and one (BJBMS) is indexed in Science Citation Index Expanded (SCIE)/Web of Science base. Aim: The aim of this study was to show the scope of work of the journals that were published by Academy of Medical Sciences of Bosnia and Herzegovina - Medical Archives, Materia Socio-Medica and Acta Informatica Medica. Material and Methods: The research presents a meta-analysis of three journals, or their issues, during the calendar year 2015 (retrospective and descriptive character). Results: During 2015 calendar year a total of 286 articles were published (in Medical Archives 104 (36.3%), in Materia Socio-Medica 99 (34.6%), and in Acta Informatica Medica 83 (29%)). Original articles are present in the highest number in all three journals (in Medical Archives 80.7%, in Materia Socio Medica 77.7%, and in Acta Informatica Medica 68.6%). In Medical Archives, 90.3% of the articles were related to the field of clinical medicine. In Materia Socio-Medica, the domain of clinical medicine and public health was the most represented. Preclinical areas are most frequent in Acta Informatica Medica. The period of 50-60 days for a decision on the admission of article is most common in all three journals, with trend of shortening of that period. Articles came from 19 countries, mostly from Bosnia and Herzegovina, then from Iran, Kosovo, Saudi Arabia and Greece. Conclusion: In Medical Archives original articles in the field of clinical medicine (usually internal and surgical disciplines) are most often present, and that is the case in last four years. The number of articles in Materia Socio-Medica and Acta Informatica Medica is growing from year to year. In Materia Socio-Medica there is a trend of growth of articles in the field of public health, while the most common articles in Acta Informatica Medica are about medical informatics.

      PubDate: Tue, 02 Feb 2016 03:03:32 GMT
       
  • Biographical Lexicon of Public Health

    • Abstract: 2015-12-10T04-17-39Z
      Source: Acta Informatica Medica
      Doncho Donev.


      PubDate: Sat, 05 Dec 2015 04:15:36 GMT
       
  • The Most Influential Scientist in the Development of Medical informatics
           (9): William Abbott

    • Abstract: 2015-12-05T04-15-32Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Sat, 05 Dec 2015 04:14:03 GMT
       
  • The Comparison of the Minimum Data Set for Elderly Health in Selected
           Countries

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Nasrin Davaridolatabadi, Mehraban Shahi, Farahnaz Sadoughi, Maryam Ahmadi.
      Introduction: Ongoing increase in the elderly population in many developed countries has drawn attention to health of this age group. Recording adequate and relevant data for the elderly is considered as the basis for future planning for this segment of society. So this study was conducted to compare minimum data about elderly health in selected countries. Methods: This review study was conducted through Internet and library studies. Key words were extracted from search engines and data bases including Google, Yahoo, Google Scholar, PubMed, ProQuest and Iranian National Medical Digital Library. Inclusion criteria included English language with no time limits. All articles, research projects, theses, guidelines and progress reports were retrieved from the United States, Sweden, Japan and Iran and reviewed. Also, websites of organizations responsible for elderly health in selected countries were visited and their documents were reviewed. Results from this search were provided narratively and finally were presented within comparison tables. Findings: The findings of this study showed that elderly data in the selected countries are collected around four axis including minimum demographic data, medical histories, health assessment and financial data of elderly health. Discussion and Conclusion: Given the importance of the minimum data set of elderly health for future planning, the use of experiences of leading countries in elderly health seems necessary; however, localization of it according to the country’s needs is inevitable.

      PubDate: Sun, 22 Nov 2015 01:48:32 GMT
       
  • Discovering Diabetes Complications: an Ontology Based Model

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Tahani Daghistani, Riyad Al Shammari, Muhammad Imran Razzak.
      Background: Diabetes is a serious disease that spread in the world dramatically. The diabetes patient has an average of risk to experience complications. Take advantage of recorded information to build ontology as information technology solution will help to predict patients who have average of risk level with certain complication. It is helpful to search and present patient’s history regarding different risk factors. Discovering diabetes complications could be useful to prevent or delay the complications. Method: We designed ontology based model, using adult diabetes patients’ data, to discover the rules of diabetes with its complications in disease to disease relationship. Result: Various rules between different risk factors of diabetes Patients and certain complications generated. Furthermore, new complications (diseases) might be discovered as new finding of this study, discovering diabetes complications could be useful to prevent or delay the complications. Conclusion: The system can identify the patients who are suffering from certain risk factors such as high body mass index (obesity) and starting controlling and maintaining plan.

      PubDate: Sun, 22 Nov 2015 01:46:44 GMT
       
  • Research on the Submission, Acceptance and Publication Times of Articles
           Submitted to International Otorhinolaryngology Journals

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      M. Tayyar Kalcioglu, Yavuz Ileri, Servet Karaca, Oguz Kadir Egilmez, Numan Kokten.
      Objective: The aim of this study was to provide insight into the acceptance and publication times of articles submitted to international otolaryngology journals. Material and Methods: The study was carried out by examining the top 37 journal titles returned in an online search for otolaryngology journals published from 1999 to 2013 that have an international status based on their impact factor. Results: In total, 9,765 publications were examined. When journals were compared based on journal impact factor, statistically significant differences (p

      PubDate: Sun, 22 Nov 2015 01:43:58 GMT
       
  • Epilepsy Research in Iran: a Scientometric Analysis of Publications Output
           During 2000-2014

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Masoud Rasolabadi, Seyedeh Moloud Rasouli-Ghahfarkhi, Marlin Ardalan, Marya Maryam Kalhor, Jamal Seidi, Alireza Gharib.
      Aim: The aim of this study is to analyze the epilepsy research output of Iran in national and global contexts, as reflected in its publication output indexed in Scopus citation database during 2000-2014.Methods: This study was based on the publications of epilepsy research from Iranian authors retrieved Feb. 2015 from Scopus Citation database [http://www.scopus.com]. The string used to retrieve the data was developed using “epilepsy OR epilepsies” keywords in title, abstract and keywords and Iran in affiliation field was our main string. Results: Cumulative publication output of Iran in epilepsy research consisted of 702 papers from 2000 to 2014, with an average number of 46.53 papers per year. The total publication output of Iran in epilepsy research increased from 2 papers in 2000 to 88 papers in 2014. Hence, with 702 paper, Iran ranked 25th among the top 25 countries with a global share of 0.82 %. Iranian publication average citation per paper increased from 0 in 2000 to 7.88 in 2014. Overall, the received citations were 3184 citations during those years. Conclusion: Iran is collaborating with 36 countries with no more than 244 of its papers (35% of its total papers). It is necessary to prepare conditions for epilepsy researchers to collaborate more with international scientific societies in order to produce more and high quality papers.

      PubDate: Sun, 22 Nov 2015 01:42:16 GMT
       
  • The Evaluation of SEPAS National Project Based on Electronic Health Record
           System (EHRS) Coordinates in Iran

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Farkhondeh Asadi, Hamid Moghaddasi, Reza Rabiei, Forough Rahimi, Soheila Jahangiri Mirshekarlou.
      Background: Electronic Health Records (EHRs) are secure private lifetime records that can be shared by using interoperability standards between different organizations and units. These records are created by the productive system that is called EHR system. Implementing EHR systems has a number of advantages such as facilitating access to medical records, supporting patient care, and improving the quality of care and health care decisions. The project of electronic health record system in Iran, which is the goal of this study, is called SEPAS. With respect to the importance of EHR and EHR systems the researchers investigated the project from two perspectives: determining the coordinates of the project and how it evolved, and incorporating the coordinates of EHR system in this project. Methods: In this study two evaluation tools, a checklist and a questionnaire, were developed based on texts and reliable documentation. The questionnaire and the checklist were validated using content validity by receiving the experts’ comments and the questionnaire’s reliability was estimated through Test-retest(r =87%).Data were collected through study, observation, and interviews with experts and specialists of SEPAS project. Results: This research showed that SEPAS project, like any other project, could be evaluated. It has some aims; steps, operational phases and certain start and end time, but all the resources and required facilities for the project have not been considered. Therefore it could not satisfy its specified objective and the useful and unique changes which are the other characteristics of any project have not been achieved. In addition, the findings of EHR system coordinates can be determined in 4 categories as Standards and rules, Telecommunication-Communication facilities, Computer equipment and facilities and Stakeholders. Conclusions: The findings indicated that SEPAS has the ability to use all standards of medical terminology and health classification systems in the case of Maksa approval (The reference health coding of Iran).ISO13606 was used as the main standard in this project. Regarding the telecommunication-communication facilities of the project, the findings showed that its link is restricted to health care centers which does not cover other institutions and organizations involved in public health. The final result showed that SEPAS is in the early stages of execution. And the full implementation of EHR needs the provision of the infrastructure of the National Health Information Network that is the same as EHR system.

      PubDate: Sun, 22 Nov 2015 01:40:20 GMT
       
  • Computer Based Assessment of Cervical Vertebral Maturation Stages Using
           Digital Lateral Cephalograms

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Vildana Dzemidzic, Emir Sokic, Alisa Tiro, Enita Nakas.
      Objective: This study was aimed to investigate the reliability of a computer application for assessment of the stages of cervical vertebra maturation in order to determine the stage of skeletal maturity. Material and methods: For this study, digital lateral cephalograms of 99 subjects (52 females and 47 males) were examined. The following selection criteria were used during the sample composition: age between 9 and 16 years, absence of anomalies of the vertebrae, good general health, no history of trauma at the cervical region. Subjects with lateral cephalograms of low quality were excluded from the study.For the purpose of this study a computer application Cephalometar HF V1 was developed. This application was used to mark the contours of the second, third and fourth cervical vertebrae on the digital lateral cephalograms, which enabled a computer to determine the stage of cervical vertebral maturation. The assessment of the stages of cervical vertebral maturation was carried out by an experienced orthodontist. The assessment was conducted according to the principles of the method proposed by authors Hassel and Farman. The degree of the agreement between the computer application and the researcher was analyzed using by statistical Cohen Kappa test. Results: The results of this study showed the agreement between the computer assessment and the researcher assessment of the cervical vertebral maturation stages, where the value of the Cohen Kappa coefficient was 0.985. Conclusion: The computer application Cephalometar HF V1 proved to be a reliable method for assessing the stages of cervical vertebral maturation. This program could help the orthodontists to identify the stage of cervical vertebral maturation when planning the orthodontic treatment for the patients with skeletal disharmonies.

      PubDate: Sun, 22 Nov 2015 01:38:52 GMT
       
  • Gender Differences in Biochemical and Electroneurographic Parameters of
           Median and Ulnar Nerve

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Merita Tiric-Campara, Emir Tupkovic, Miro Denislic, Mirza Biscevic, Amira Skopljak, Jasminka Djelilovic-Vranic, Azra Alajbegovic.
      Introduction: In this article are demonstrated differences in the aspects of the metabolic syndrome (MSy) between genders, as well as the association of MSy and neuropathy. The aim: The aim of our study was that in patients with newly discovered metabolic syndrome of both sexes make comparison of fasting blood glucose levels and after oral glucose tolerance test, as well as neurophysiological parameters of n.medianus and n.ulnaris. Patients and methods: All participants were examined dermatologically. The analysis included the 36 male and 36 female respondents with a newly discovered MSy. Results: The average age of men was 52.75±7.5 (40-65) years and women 52.1±7.7 (38-67) years. The average value of fasting blood glucose in women was 5.86±0.87 (4.5-8) mmol/L, and non significantly higher in men (p=0.0969) as 6.19±0.8 (4.7-8) mmol/L. Average values of blood sugar 120 minutes after oral glucose tolerance test were not significantly different (p=0.7052), and was 5.41±1.63 (3.3-9.7) mmol/L in women and 5.27±1.52 (2.7-9.8) mmol/L in men. Median motor velocity were significantly higher in women for n.medianus on the left (p=0.0024), n.ulnaris on the left (p=0.0081) and n.ulnaris on the right side (p=0.0293), and the median motor terminal latency were significantly longer in n.ulnaris on the left (p=0.0349) and n.ulnaris on the right side (p=0.011). There was no significant difference in the sensory conductivity velocity in n.medianus and n.ulnaris between the groups, but the amplitude with the highest peak of the sensory response was significantly higher in n.medianus on the left (p=0.0269) and n.ulnaris on the left side (p=0.0009) in female patients. Conclusion: The results indicate that there are differences in neurophysiological parameters of the investigated nerves between the genders, and that tested nerve structures in the course of MSy are affected slightly more in men. There were no significant differences in skin changes between genders.

      PubDate: Sun, 22 Nov 2015 01:37:01 GMT
       
  • The Usage of Association Rule Mining to Identify Influencing Factors on
           Deafness After Birth

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Azimeh Danesh Shahraki, Reza Safdari, Hamid Habibi Gahfarokhi, Shahram Tahmasebian.
      Background: Providing complete and high quality health care services has very important role to enable people to understand the factors related to personal and social health and to make decision regarding choice of suitable healthy behaviors in order to achieve healthy life. For this reason, demographic and clinical data of person are collecting, this huge volume of data can be known as a valuable resource for analyzing, exploring and discovering valuable information and communication. This study using forum rules techniques in the data mining has tried to identify the affecting factors on hearing loss after birth in Iran. Materials and Methods: The survey is kind of data oriented study. The population of the study is contained questionnaires in several provinces of the country. First, all data of questionnaire was implemented in the form of information table in Software SQL Server and followed by Data Entry using written software of C # .Net, then algorithm Association in SQL Server Data Tools software and Clementine software was implemented to determine the rules and hidden patterns in the gathered data. Findings: Two factors of number of deaf brothers and the degree of consanguinity of the parents have a significant impact on severity of deafness of individuals. Also, when the severity of hearing loss is greater than or equal to moderately severe hearing loss, people use hearing aids and Men are also less interested in the use of hearing aids. Conclusion: In fact, it can be said that in families with consanguineous marriage of parents that are from first degree (girl/boy cousins) and 2nd degree relatives (girl/boy cousins) and especially from first degree, the number of people with severe hearing loss or deafness are more and in the use of hearing aids, gender of the patient is more important than the severity of the hearing loss.

      PubDate: Sun, 22 Nov 2015 01:35:21 GMT
       
  • Pachymetric Changes of the Cornea Amongst Patients Treated with LASIK

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Afrim Shabani, Minir Asani, Gazmend Kaçaniku, Valbon Ajazaj, Ermal Dida, Pajtim Lutaj.
      Purpose: In this study, we have researched the possible parametrically changes before and after LASIK (laser-assisted in situ keratomileusis) and the influence of these changes in the cause of post LASIK ectasia. Materials and methods: In this study 204 eyes with different refractive anomalies were included. Candidates that underwent refractive surgery first have to undergo many ophthalmological examinations, firstly by evaluating their visual acuity, subjective and objective refraction with and without cycloplegia, slight lamp evaluation, computerized topography, pupillometry, retina examination and measurement of intraocular pressure. Pachymetric values were measured with Orbscan IIz (Bausch – Lomb). Refractive surgery was done with LASIK under local anesthesia. Results: In this study 102 patients were treated with LASIK who were with different refractive anomalies. According to the group age 44 or 43.1% were of the age 20 – 29, 46 or 45.1% were of the age 30 – 39, 11 or 10.8% were 40 – 49 years of age and 1 or 1% were above the age of 50 +. Pachymetric before surgery in right eye was approximately 565.4 μm (DS+- 39.4), from 507 μm up to 678 μm, but after surgery it was approximately 497.5 μm (DS+-61.7) from 346 μm up to 644 μm. Pachymetric on the left eye before surgery was approximately 564.8 μm (DS+-41.5) from 504 μm up to 696 μm but after surgery it was approximately 498.3 μm (DS+-62.2), from 329 μm up to 646 μm. Pachymetric in both eyes before surgery was approximately 549.1 μm (DS+=73.9), from 263 μm up to 687 μm. Pachymetric on both eyes after surgery was approximately 496.9 μm (DS+-60.1), from 337.5 μm up to 645 μm. With the “ Paired T – test ” we have reached a significant statistical change between the pachymetric values in both eyes before and after the surgery (P

      PubDate: Sun, 22 Nov 2015 01:33:35 GMT
       
  • Comparison of Glucocorticoid (Budesonide) and Antileukotriene
           (Montelukast) Effect in Patients with Bronchial Asthma Determined with
           Body Plethysmography

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Njomza Lajqi, Ali Ilazi, Bashkim Kastrati, Hilmi Islami.
      Objective: Effect of glucocorticoids-budesonide and antileukotriene–montelukast in patients with bronchial asthma and bronchial increased reactivity was studied in this work. Methods: Parameters of the lung function are determined with Body plethysmography. Raw and ITGV were registered and specific resistance (SRaw) was also calculated. Results: Results of this research, in patients with bronchial asthma, indicate that glucocorticoids – budesonide (Pulmicort; 2 x 2 mg inh) has significant action (p< 0.01) on reduction of the specific resistance (SRaw) of airways, applied to the same patients 3 days after administration of montelukast, at home (2 x 10 mg). Three days after administration of the montelukast, antileukotriene medicine, at home, on the fourth day same patients administered a capsule of montelukast, 10 mg dose per os, and significantly (p < 0.05) reduced the increased bronchomotor tonus; and the effect of the control with salbutamol (beta2-adrenergic agonist) is effective in removal of the increased bronchomotor tonus, causing significant decrease of the resistance (Raw), respectively of the specific resistance (SRaw), (p < 0, 01). Conclusion: This suggests that the bronchodilator effect of glucocorticoids is more powerful than of the leukotriene, because glucocorticoids terminate the early stage of chemical mediator release (prostaglandins PgD2, SRS, and leukotriene LTC4, LTD4, LTE4 and Cytokinins also etc.) as powerful bronchoconstriction substances, whilst antileukotriene substances does not have this feature.

      PubDate: Sun, 22 Nov 2015 01:31:50 GMT
       
  • Interictal Electroencephalography (EEG) Findings in Children with Epilepsy
           and Bilateral Brain Lesions on Magnetic Resonance Imaging (MRI)

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Smail Zubcevic, Maja Milos, Feriha Catibusic, Sajra Uzicanin, Belma Krdzalic.
      Introduction: Neuroimaging procedures and electroencephalography (EEG) are basic parts of investigation of patients with epilepsies. Aim: The aim is to try to assess relationship between bilaterally localized brain lesions found in routine management of children with newly diagnosed epilepsy and their interictal EEG findings. Patients and methods: Total amount of 68 patients filled criteria for inclusion in the study that was performed at Neuropediatrics Department, Pediatric Hospital, University Clinical Center Sarajevo, or its outpatient clinic. There were 33 girls (48,5%) and 35 boys (51,5%). Average age at diagnosis of epilepsy was 3,5 years. Results: Both neurological and neuropsychological examination in the moment of making diagnosis of epilepsy was normal in 27 (39,7%) patients, and showed some kind of delay or other neurological finding in 41 (60,3%). Brain MRI showed lesions that can be related to antenatal or perinatal events in most of the patients (ventricular dilation in 30,9%, delayed myelination and post-hypoxic changes in 27,9%). More than half of patients (55,9%) showed bilateral interictal epileptiform discharges on their EEGs, and further 14,7% had other kinds of bilateral abnormalities. Frequency of bilateral epileptic discharges showed statistically significant predominance on level of p

      PubDate: Sun, 22 Nov 2015 01:30:25 GMT
       
  • The Event-related Potential P300 in Patients with Migraine

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Marina Titlic, Nikolina Ivica Mise, Irena Pintaric, Veljko Rogosic, Lucija Vanjaka-Rogosic, Mario Mihalj, Pavao Jurinovic, Ana Curkovi&#; Katic, Maja Andjelinovic.
      Objective: Recording of event-related potentials by using oddball paradigm of auditory P300 has yielded conflicting results in migraine. The aim of this study was to demonstrate that migraine patients have reduced P300 amplitude and prolonged P300 latency, suggesting alterations of the cognitive-evaluative component. Methods: We recruited 29 migraine patients (24 females; median age 40 years) and 29 healthy age- and gender-matched participants. Participants were subjected to the same testing procedures of auditory P300 by discrimination the target auditory stimulus from the frequent stimulus, and analyzing P300 target/frequent stimulus amplitudes, and P300 target/frequent stimulus latencies. Results: Patients with migraine don’t have prolonged P300 target stimulus latency, but have a longer P300 frequent stimulus latency for 17.5ms. Out of 29 participants with migraine 8 had pathological P300 target stimulus amplitude, and 19 had pathological P300 frequent stimulus amplitude. Conclusion: People with migraine have altered the P300 which indicates the presence of cognitive dysfunction in these patients and importance of early diagnosis and intervention to preventing any deterioration in cognitive functions.

      PubDate: Sun, 22 Nov 2015 01:28:55 GMT
       
  • Designing Decision Support System to Detect Drug Interactions Type 2
           Diabetes

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Mehdi Rasoolimoghadam, Reza Safdari, Marjan Ghazisaeidi, MohammadReza Maharanitehrani, Shahram Tahmasebiyan.
      Background and Aim: Type II Diabetes is the most common diseases of metabolic disorders and the treatment of oral anti-diabetic drug use takes place But The problem of using multi-drug and interactions at the same time is an issue that has always been a major challenge And diagnosis of drug interactions, particularly in Diabetic patients due to the problem with the disease is very important. The purpose of this studying is, to design a clinical assistant decided to use this approach to determine the type II diabetes drug interactions this makes it easy for those who are active in the field. Materials and Methods: Study is Developmental that to determine the content of the system a self-made checklist was used. Checklist Validity and reliability has been confirmed by four professors. The Research community to determine the content of the system was country endocrine that are 124 people.  The sample size was calculated using Cochran that was 57 people. The Score of checklist was calculated in SPSS version 20 .finally, the checklist was approved by at least 70% points. The system by using Microsoft SQL server 2008 and visual Studio 2012 development environment was designed in C#.net. In the end, In order to evaluate the software to determine the level of satisfaction, usability and ease of use, designed systems sharing with all Medical Informatics students of Tehran University of Medical Sciences. For this purpose a self-made questionnaire was used. Questionnaire Validity has been confirmed by four professors and reliability was assessed by Cronbach method. Results: The results of the survey are showing that the majority of students found out and believed the software is useful and easy to use and generally expressed their satisfaction software. Conclusions: The methodology provides a suitable approach for analysis and modeling of data in the medical field and the performance is good.

      PubDate: Sun, 22 Nov 2015 01:27:33 GMT
       
  • The Most Influential Scientists in the Development of Medical Informatics
           (8): Jean Raoul Scherrer

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Mon, 05 Oct 2015 13:03:25 GMT
       
  • Chromatography as Method for Analytical Confirmation of Paracetamol in
           Postmortem Material Together with Psychoactive Substances

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Jasmina Biscevic-Tokic, Nedim Tokic, Elma Ibrahimpasic.
      Introduction: Paracetamol (Acetaminophen) in addition to aspirin is the most commonly used analgesic and antipyretic medication by millions of patients worldwide. It is an example that paracetamol as medicine that in the world is provided without a doctor’s prescription, can lead to death. Today paracetamol became an integral part of a heroin mixture and is very popular at the street market. The main reason for this is that it can be obtained without a prescription, it is cheap, and by most people well tolerated without side effects. It is probably used for “cutting” the pure heroin, as it says in the jargon, and in that manner from small amount of pure drug is obtained greater amount, which is then sold on the street. The goal is to identify presence of paracetamol, by analytical method of gas chromatography mass spectrometer (GC-MS) in postmortem material together with psychoactive substances. Material and methods: For chemical-toxicological analysis is used biological material collected trough autopsy of 20 deceased people, suspected to have died due to psychoactive substance overdose. All received samples are stored at -20 ° C until analysis at our laboratory. From processed 47 samples that were analyzed in the period from 2014 to 2015, 19 are blood samples, urine 19, 3 samples of stomach contents, and 6 samples of bile content. Deceased were middle-aged, of which only 7 were female. The tested samples were processed according to two methods of extraction. Extraction by XAD-2 resin, and the extraction by the method of salting out with sodium tungstate. Extracts of the samples were then dissolved in chloroform and continued analysis at the analytical instrument. Identification of the paracetamol presence, in the test biological samples is demonstrated by the technique of gas chromatography with mass spectometry (hereinafter referred to as GC-MS). The technique of GC-MS is a selective, sensitive and reliable, and is therefore considered a “gold standard” for determining the drug, and the drug substance. Used GC-MS instrument was an Agilent 7890A with helium as the carrier gas. Results: The analysis of blood samples, urine, bile and stomach contents, obtained after the autopsy of deceased persons, by using gas chromatography with mass spectrometry, in analytical manner confirmed the fact that paracetamol is a very common component of psychoactive substances poisoning. In our assay of samples we detected psychoactive substances (heroin, codeine, morphine, sertraline, diazepam), and almost all were found in the combination with paracetamol, indicating the poor quality of illicit drugs sold on the market. Discussion: Paracetamol (Acetaminophen) is a very common component in mixtures of street drugs. Such mixtures almost anyone can afford, but the very quality of these drugs has become extremely low, because it does not sell the pure substance, but is mixed with various medications. According to research Pantazia et al. the heroin mixture proportion of the heroin is very small so a lot of that mixture has only 3% of heroin, a large number of cases can be only 1% of pure heroin. Most of the time it replaces caffeine and paracetamol. According to the Risser et al. reason why acetaminophen component is present in these mixtures is because it can be purchased without a prescription, it is cheap, well tolerated by most people and shows no side effects. Conclusion: When we talk about illegal drugs, we must emphasize the fact that there is no quality control, or the composition of the drug. The composition of the drug purchased on the black market is still unknown to potential user. While reaching the final drug users it pass through many hands, and at each step something is added to increase earnings. Most often present additives or impurities in narcotic drugs that are added are caffeine, ephedrine, acetaminophen, acetylsalicylic acid (aspirin) and additives such as powders, cement and chalk.

      PubDate: Mon, 05 Oct 2015 13:01:20 GMT
       
  • Development of Performance Dashboards in Healthcare Sector: Key Practical
           Issues

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Marjan Ghazisaeidi, Reza Safdari, Mashallah Torabi, Mahboobeh Mirzaee, Jebraeil Farzi, Azadeh Goodini.
      Background: Static nature of performance reporting systems in health care sector has resulted in inconsistent, incomparable, time consuming, and static performance reports that are not able to transparently reflect a round picture of performance and effectively support healthcare managers’ decision makings. So, the healthcare sector needs interactive performance management tools such as performance dashboards to measure, monitor, and manage performance more effectively. The aim of this article was to identify key issues that need to be addressed for developing high-quality performance dashboards in healthcare sector. Methods: A literature review was established to search electronic research databases, e-journals collections, and printed journals, books, dissertations, and theses for relevant articles. The search strategy interchangeably used the terms of “dashboard”, “performance measurement system” and “executive information system” with the term of “design” combined with operator “AND”. Search results (n=250) were adjusted for duplications, screened based on their abstract relevancy and full-text availability (n=147) and then assessed for eligibility (n=40). Eligible articles were included if they had explicitly focused on dashboards, performance measurement systems or executive information systems design. Finally, 28 relevant articles included in the study. Results: Creating high-quality performance dashboards requires addressing both performance measurement and executive information systems design issues. Covering these two fields, identified contents were categorized to four main domains: KPIs development, Data Sources and data generation, Integration of dashboards to source systems, and Information presentation issues. Conclusion: This study implies the main steps to develop dashboards for the purpose of performance management. Performance dashboards developed on performance measurement and executive information systems principles and supported by proper back-end infrastructure will result in creation of dynamic reports that help healthcare managers to consistently measure the performance, continuously detect outliers, deeply analyze causes of poor performance, and effectively plan for the future.

      PubDate: Mon, 05 Oct 2015 12:59:37 GMT
       
  • Designing of Intelligent Multilingual Patient Reported Outcome System
           (IMPROS)

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Faramarz Pourasghar, Yeganeh Partovi.
      Background: By self-reporting outcome procedure the patients themselves record disease symptoms outside medical centers and then report them to medical staff in specific periods of time. One of the self-reporting methods is the application of interactive voice response (IVR), in which some pre-designed questions in the form of voice tracks would be played and then the caller responses the questions by pressing phone’s keypad bottoms. Aim: The present research explains the main framework of such system designing according to IVR technology that is for the first time designed and administered in Iran. Methods: Interactive Voice Response system was composed by two main parts of hardware and software. Hardware section includes one or several digital phone lines, a modem card with voice playing capability and a PC. IVR software on the other hand, acts as an intelligent control center, records call information and controls incoming data. Results: One of the main features of the system is its capability to be administered in common PCs, utilizing simple and cheap modems, high speed to take responses and it’s appropriateness to low literate patients. The system is applicable for monitoring chronic diseases, cancer and also in psychological diseases and can be suitable for taking care of elders and Children who require long term cares. Other features include user-friendly, decrease in direct and indirect costs of disease treatment and enjoying from high level of security to access patients’ profiles. Conclusions: Intelligent multilingual patient reported outcome system (IMPROS) by controlling diseases gives the opportunity to patients to have more participation during treatment and it improves mutual interaction between patient and medical staff. Moreover it increases the quality of medical services, Additional to empowering patients and their followers.

      PubDate: Mon, 05 Oct 2015 12:57:28 GMT
       
  • Quantitative and Qualitative Evaluation of The Structural Designing of
           Medical Informatics Dynamic Encyclopedia

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Reza Safdari, Leila Shahmoradi, Molouk-sadat Hosseini-beheshti, Ahmadreza Farzaneh Nejad, Mohammad Hosseiniravandi.
      Introduction: Encyclopedias and their compilation have become so prevalent as a valid cultural medium in the world. The daily development of computer industry and the expansion of various sciences have made indispensable the compilation of electronic, specialized encyclopedias, especially the web-based ones. Materials and Methods: This is an applied-developmental study conducted in 2014. First, the main terms in the field of medical informatics were gathered using MeSH Online 2014 and the supplementary terms of each were determined, and then the tree diagram of the terms was drawn based on their relationship in MeSH. Based on the studies done by the researchers, the tree diagram of the encyclopedia was drawn with respect to the existing areas in this field, and the terms gathered were put in related domains. Findings: In MeSH, 75 preferred terms together with 249 supplementary ones were indexed. One of the informatics’ sub-branches is biomedical informatics and health which itself consists of three sub-divisions of bioinformatics, clinical informatics, and health informatics. Medical informatics which is a subdivision of clinical informatics has developed from the three fields of medical sciences, management and social sciences, and computational sciences and mathematics. Results and Discussion: Medical Informatics is created of confluence and fusion and applications of the three major scientific branches include health and biological sciences, social sciences and management sciences, computing and mathematical sciences, and according to that the structure of MeSH is weak for future development of Encyclopedia of Medical Informatics.

      PubDate: Mon, 05 Oct 2015 12:55:42 GMT
       
  • Quantitative and Qualitative Evaluation of Iranian Researchers’
           Scientific Production in Dentistry Subfields

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Mousa Yaminfirooz, Mina Motallebnejad, Hemmat Gholinia, Somayeh Esbakian.
      Background: As in other fields of medicine, scientific production in the field of dentistry has significant placement. This study aimed at quantitatively and qualitatively evaluating Iranian researchers’ scientific output in the field of dentistry and determining their contribution in each of dentistry subfields and branches. Methods: This research was a scientometric study that applied quantitative and qualitative indices of Web of Science (WoS). Research population consisted of927indexed documents published under the name of Iran in the time span of 1993-2012 which were extracted from WoS on 10 March 2013. The Mann-Whitney test and Pearson correlation coefficient were used to data analyses in SPSS 19. Results: 777 (83. 73%) of indexed items of all scientific output in WoS were scientific articles. The highest growth rate of scientific productionwith90% belonged to endodontic sub field. The correlation coefficient test showed that there was a significant positive relationship between the number of documents and their publication age (P < 0. 0001). There was a significant difference between the mean number of published articles in the first ten- year (1993-2003) and that of the second one (2004-2013), in favor of the latter (P = 0. 001). Conclusions: The distribution frequencies of scientific production in various subfields of dentistry were very different. It needs to reinforce the infrastructure for more balanced scientific production in the field and its related subfields.

      PubDate: Mon, 05 Oct 2015 12:53:40 GMT
       
  • A Comparison of Logistic Regression Model and Artificial Neural Networks
           in Predicting of Student’s Academic Failure

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Saeed Hosseini Teshnizi, Sayyed Mohhamad Taghi Ayatollahi.
      Background and objective: Artificial Neural Networks (ANNs) have recently been applied in situations where an analysis based on the logistic regression (LR) is a standard statistical approach; direct comparisons of the results, however, are seldom attempted. In this study, we compared both logistic regression models and feed-forward neural networks on the academic failure data set. Methods: The data for this study included 18 questions about study situation of 275 undergraduate students selected randomly from among nursing and midwifery and paramedic schools of Hormozgan University of Medical Sciences in 2013. Logistic regression with forward method and feed forward Artificial Neural Network with 15 neurons in hidden layer were fitted to the dataset. The accuracy of the models in predicting academic failure was compared by using ROC (Receiver Operating Characteristic) and classification accuracy. Results: Among nine ANNs, the ANN with 15 neurons in hidden layer was a better ANN compared with LR. The Area Under Receiver Operating Characteristics (AUROC) of the LR model and ANN with 15 neurons in hidden layers, were estimated as 0.55 and 0.89, respectively and ANN was significantly greater than the LR. The LR and ANN models respectively classified 77.5% and 84.3% of the students correctly. Conclusion: Based on this dataset, it seems the classification of the students in two groups with and without academic failure by using ANN with 15 neurons in the hidden layer is better than the LR model.

      PubDate: Mon, 05 Oct 2015 12:52:25 GMT
       
  • The Use of an Adapted Health IT Usability Evaluation Model (Health-ITUEM)
           for Evaluating Consumer Reported Ratings of Diabetes mHealth Applications:
           Implications for Diabetes Care and Management

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Mowafa S. Househ, Mamdouh M. Shubair, Faisel Yunus, Amr Jamal, Bakheet Aldossari.
      Background: The aim of this paper is to present a usability analysis of the consumer ratings of key diabetes mHealth applications using an adapted Health IT Usability Evaluation Model (Health-ITUEM). Methods: A qualitative content analysis method was used to analyze publicly available consumer reported data posted on the Android Market and Google Play for four leading diabetes mHealth applications. Health-ITUEM concepts including information needs, flexibility/customizability, learnability, performance speed, and competency guided the categorization and analysis of the data. Health impact was an additional category that was included in the study. A total of 405 consumers’ ratings collected from January 9, 2014 to February 17, 2014 were included in the study. Results: Overall, the consumers’ ratings of the leading diabetes mHealth applications for both usability and health impacts were positive. The performance speed of the mHealth application and the information needs of the consumers were the primary usability factors impacting the use of the diabetes mHealth applications. There was also evidence on the positive health impacts of such applications. Conclusions: Consumers are more likely to use diabetes related mHealth applications that perform well and meet their information needs. Furthermore, there is preliminary evidence that diabetes mHealth applications can have positive impact on the health of patients.

      PubDate: Mon, 05 Oct 2015 12:51:00 GMT
       
  • Evaluation of Pharyngeal Space in Different Combinations of Class II
           Skeletal Malocclusion

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Jay Soni, Tarulatha R. Shyagali, Deepak P. Bhayya, Romil Shah.
      Objectives: The study was aimed to evaluate the pharyngeal airway linear measurements of untreated skeletal class II subjects with normal facial vertical pattern in prognathic maxilla with orthognathic mandible and orthognathic maxilla with retrognathic mandible. Materials and method: the sample comprised of lateral Cephalograms of two groups (30 each) of class II malocclusion variants. Group 1 comprised of class II malocclusion with prognathic maxilla and orthognathic mandible, whereas group 2 comprised of class II malocclusion with orthognathic maxilla and retrognathic mandible. Each group was traced for the linear measurements of the pharyngeal airway like the oropharynx, nasopharynx and soft palate. The obtained data was subjected to independent t test and the Mann Whitney test to check the difference between the two groups and within the groups respectively. Results: there was significant difference between all the linear measurements at the soft palate region and the distance between the tip of soft palate to its counter point on the pharyngeal wall in oropharynx region (p-ppm). Conclusion: the pharyngeal airway for class II malocclusion with various combination in an average growth pattern adult showed significant difference. The present results suggested, that the pharyngeal airway space might be the etiological factor for different sagittal growth pattern of the jaws and probable usage of different growth modification appliance can influence the pharyngeal airway.

      PubDate: Mon, 05 Oct 2015 12:49:39 GMT
       
  • Evaluation of the Hemodynamic Response to Endotracheal Intubation
           Comparing the Airtraq® with Macintosh Laryngoscopes in Cardiac
           Surgical Patients

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Aleksandra Gavrilovska-Brzanov, Mohhamed Al Jarallah, Andrea Cogliati, Maja Mojsova-Mijovska, Dragan Mijuskovic, Dimce Slaveski.
      Introduction: Cardiac patients are more prone to develop hemodynamic instability on induction of anesthesia and endotracheal intubation. The Airtraq® ® optical laryngoscope is a single-use rigid video laryngoscope that has been developed to facilitate tracheal intubation. There are limited studies comparing differences in the circulatory responses to Airtraq® and direct Macintosh larynngoscopy in cardiac patients. Aim: The purpose of our study was to evaluate whether there was clinically significant difference between the hemodynamic response to orotracheal intubation guided by either of the two devices (Airtraq® and Macintosh laryngoscopes) in patients who underwent coronary artery bypass grafting surgery. Material and methods: In this clinical study we analyzed the hemodynamic response to endotracheal intubation performed with Airtraq® or Macintosh laryngoscopes in patients who underwent elective coronary artery bypass graft surgery under general anesthesia. Results: We analyzed: blood pressure (systolic, diastolic, mean), heart rate and peripheral oxygen saturation (all notified before induction in anesthesia, immediately after induction, at the time of intubation and thereafter one and five minutes after intubation). We also recorded the maximal values of blood pressure and heart rate, as well as calculated the product of heart rate and systolic blood pressure. There were statistically significant differences in the hemodynamic response between the groups. At the time of intubation, there was significant inter-group difference in heart rate, systolic, diastolic and mean blood pressure. Endotracheal intubation with Macintosh laryngoscope was accompanied by significant increase in blood pressure and heart rate compared to Airtraq® group. Conclusion: The Airtraq® laryngoscope performed better than the Macintosh laryngoscope in terms of hemodynamic to the patient undergoing routine coronary artery bypass graft surgery.

      PubDate: Mon, 05 Oct 2015 12:48:21 GMT
       
  • Echocardiography Differences Between Athlete’s Heart Hearth and
           Hypertrophic Cardiomyopathy

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Amir Kreso, Fahir Barakovic, Esad Medjedovic, Amila Halilbasic, Muhamed Klepic.
      Introduction: Among long term athletes there is always present hypertrophy of the left ventricle walls as well as increased cardiac mass. These changes are the result of the heart muscle adaptation to load during the years of training, which should not be considered as pathology. In people suffering from hypertrophic cardiomyopathy (HCM), there is also present hypertrophy of the left ventricle walls and increased mass of the heart, but these changes are the result of pathological changes in the heart caused by a genetic predisposition for the development HCM of. Differences between myocardial hypertrophy in athletes and HCM are not clearly differentiated and there are always dilemmas between pathological and physiological hypertrophy. The goal of the study is to determine and compare the echocardiographic cardiac parameters of longtime athletes to patients with hypertrophic cardiomyopathy. Material and methods: The study included 60 subjects divided into two groups: active athletes and people with hypertrophic cardiomyopathy. Results: Mean values of IVSd recorded in GB is IVSd=17.5 mm (n=20, 95% CI, 16.00–19.00 mm), while a significantly smaller mean value is recorded in GA, IVSd=10.0 mm (n=40, 95% CI, 9.00-11.00 mm). The mean value of the left ventricle in diastole (LVDd) recorded in the GA is LVDd=51 mm (n=40; 95% CI, 48.00 to 52.00 mm), while in the group with hypertrophic cardiomyopathy (GB) mean LVDd value is 42 mm (n=20; 95% CI, 40.00 to 48.00 mm). The mean value of the rear wall of the left ventricle (LVPWd) recorded in the GA is LVDd=10 mm (n=40; 95% CI, 9.00-10.00 mm) while in the group with hypertrophic cardiomyopathy (GB) mean LVDd is 14 mm (n=20; 95% CI, 12.00 to 16.00 mm). The mean of the left ventricle during systole (LVSD) observed in GA is LVSD=34 mm (n=40; 95% CI, 32.00 to 36.00 mm), while in the group with hypertrophic cardiomyopathy (GB) mean LVSD is 28 mm (n=20; 95% CI, 24.00 to 28.83 mm). The mean ejection fraction (EF%) observed in GA is EF=60% (n=40; 95% CI, 56.41 to 63.00%), while in the group with hypertrophic cardiomyopathy (GB) mean EF value is 69% (n=20; 95% CI, 62.00 to 70.83 mm). Somewhat higher mean diastolic left ventricular function (E/A) was observed in GA, E/A=1.76±0.15, and lower average values in the group with hypertrophic cardiomyopathy (GB) E/A=0.78±0.02. Conclusion: Mean values of parameters: intraventricular septum thickness in diastole (IVSd), the thickness of the rear wall of the left ventricle (LVPWd), the diameter of the left ventricle during systole (LVSD) were statistically different between groups of athletes (GA) compared to the group of patients with hypertrophic cardiomyopathy (GB).

      PubDate: Mon, 05 Oct 2015 12:45:53 GMT
       
  • Contrast Media Injector Technology - Renal Safety During Coronarography

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Ermina Mujicic, Ekrem Kevric, Senija Rasic, Amina Selimovic, Nermir Granov, Dinka Music.
      Aim: This study sought to assess whether the volume and osmolarity of contrast media (CM) influences the occurrence of contrast induced nephropathy (CIN) following coronarography procedure. CIN can be defined as an increase in the serum concentration of creatinine greater than a 25% from baseline during the period of 12 to 48 hours after the administration of radiocontrast media. Material and methods: We examined 100 patients without diabetes with serum creatinine concentration from 45 mmol/l to 141 mmol/l and 100 patients with diabetes with serum creatinine concentration from 46 mmol/l to 161 mmol/l who underwent coronary angiography. During procedure they received iso-osmolar contrast medium, Visipaque 320 (iodixanol-320), for group without diabetes from 40 to 340 ml and for group with diabetes from 49 to 310 ml. Results: CIN occurred in 27 (13,5%) of the 200 study patients. There was a trend toward higher prevalence of CIN (16% vs.11%, p = 0.086) in the diabetic group compared with the non-diabetic group. Patient with diabetes received less contrast media, they are younger but number patients with CIN are higher. Conclusion: Increasing contrast media dose is associated with the occurrence of CIN following coronarography. But, another risk factors like diabetes mellitus, old age, male sex and preexisting kidney disease have influence of developing CIN after coronarography.

      PubDate: Mon, 05 Oct 2015 12:44:46 GMT
       
  • Significance of Sonographically Demonstrated Ureteral Dilatation in
           Evaluation of Vesicoureteral Reflux Verified with Voiding Urosonography in
           Children with Urinary Tract Infection

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Aladin Carovac, Sandra Vegar Zubovic, Marklena Carovac, Irmina Sefic Pasic.
      Objectives. The aim of this study was to determine sensitivity, specificity, and predictive values of sonographically demonstrated ureteral dilatation in detecting vesicoureteral reflux (VUR). Methods. Ethical approval from the Ethical Committee of Clinical Center University of Sarajevo and parental consent were obtained for this prospective study involving 120 children with history of urinary tract infections (UTIs). Ultrasound examination included the evaluation of the urinary tract, with a special emphasis on evaluation of ureteral dilatation. Voiding urosonography (VUS) was carried out according to a standard protocol with the use of ultrasound contrast agent Sono Vue of second generation. Ureteral diameter greater than 3 mm was considered pathological. Proven VUR was graded into one of three stages. Results. Infectio tracti urinarii recidivans was referral diagnosis in the majority of patients. The average age of patients was 4.33 ± 3.88 years (from 2 months to 16 years of age). VUS findings were normal in 59 (49.2%), and pathological in 61 (50.8%) patients. Statistical analysis showed significant correlation between type and grade of VUR. Our data confirmed predominance of VUR in females and in children under the age of 5. Statistically significant correlation between ureteral dilatation and the existence of VUR was found, with relatively high sensitivity (67.2%), specificity (81.4%), and high positive (78.8%) and negative predictive value (70.6%), total diagnostic accuracy of 74.2% in detecting VUR, and significantly increased probability (20 – 25%) of detecting VUR in patients with sonographically confirmed ureteral dilatation. Conclusion. Sonographically confirmed ureteral dilatation can be used as a predictor of VUR in children with UTIs, and in combination with other predictors, might find a place in an evidence-based selective strategy in children with suspected VUR.

      PubDate: Mon, 05 Oct 2015 12:42:45 GMT
       
  • Influence of the Inherited Glucose-6-phosphate Dehydrogenase Deficiency on
           the Appearance of Neonatal Hyperbilirubinemia in Southern Croatia

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Anet Papazovska Cherepnalkovski, Eugenija Marusic, Katica Piperkova, Bernarda Lozic, Ana Skelin, Todor Gruev, Vjekoslav Krzelj.
      Background: Neonatal hyperbilirubinemia is a common clinical manifestation of the inherited glucose-6-phosphate dehydrogenase (G6PD) deficiency. Aim of the study: The aim of this study was to investigate the influence of the inherited G6PD deficiency on the appearance of neonatal hyperbilirubinemia in southern Croatia. Methods: The fluorescent spot test (FST) was used in a retrospective study to screen blood samples of 513 male children who had neonatal hyperbilirubinemia, of unknown cause, higher than 240 µmol/L. Fluorescence readings were performed at the beginning and at the fifth and tenth minute of incubation and were classified into three groups: bright fluorescence (BF), weak fluorescence (WF) and no fluorescence (NF). Normal samples show bright fluorescence. All NF and WF samples at the fifth minute were quantitatively measured using the spectrophotometric method. Results: Bright fluorescence was present in 461 patients (89.9%) at the fifth minute. The remaining 52 (10.1%) were quantitatively estimated using the spectrophotometric method. G6PD deficiency was observed in 38 patients (7.4%). Conclusions: Prevalence rate of G6PD deficiency among male newborns with hyperbilirubinemia in southern Croatia is significantly higher (p < 0.01) compared with the previously reported prevalence rate among male in general population of southern Croatia (0.75%). We recommend FST to be performed in hyperbilirubinemic newborns in southern Croatia.

      PubDate: Mon, 05 Oct 2015 12:41:17 GMT
       
  • Biographical Lexicon of Medical Informatics

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Gjuro Dezelic.
      Author: Prof Izet Masic, MD, PhD Publisher: AVICENA, d.o.o., Sarajevo, year 2015., 300 pages, hard cover. ISBN 978-9958-720-57-4; COBISS.BH-ID 21884422

      PubDate: Thu, 30 Jul 2015 07:25:34 GMT
       
  • 13th International Conference on Informatics, Management and Technology in
           Healthcare, Athens, Greece, 9-11 July, 2015

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Thu, 30 Jul 2015 07:24:23 GMT
       
  • International Joint Meeting EuroMISE 2015 Prague, Czech Republic, June
           16-18, 2015

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Thu, 30 Jul 2015 07:21:18 GMT
       
 
 
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