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Journal Cover Acta Informatica Medica
  This is an Open Access Journal Open Access journal
     ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
     Published by ScopeMed Homepage  [77 journals]   [H-I: 2]
  • Occupational Overuse Syndrome (Technological Diseases): Carpal Tunnel
           Syndrome, a Mouse Shoulder, Cervical Pain Syndrome

    • Abstract: 2014-11-13T08-33-20Z
      Source: Acta Informatica Medica
      Merita Tiric-Campara, Ferid Krupic, Mirza Biscevic, Emina Spahic, Kerima Maglajlija, Zlatan Masic, Lejla Zunic, Izet Masic.
      Technological diseases are diseases of the modern era. Some are caused by occupational exposures, and are marked with direct professional relation, or the action of harmful effects in the workplace. Due to the increasing incidence of these diseases on specific workplaces which may be caused by one or more causal factors present in the workplace today, these diseases are considered as professional diseases. Severity of technological disease usually responds to the level and duration of exposure, and usually occurs after many years of exposure to harmful factor. Technological diseases occur due to excessive work at the computer, or excessive use of keyboards and computer mice, especially the non-ergonomic ones. This paper deals with the diseases of the neck, shoulder, elbow and wrist (cervical radiculopathy, mouse shoulder and carpal tunnel syndrome), as is currently the most common diseases of technology in our country and abroad. These three diseases can be caused by long-term load and physical effort, and are tied to specific occupations, such as occupations associated with prolonged sitting, working at the computer and work related to the fixed telephone communication, as well as certain types of sports (tennis, golf and others).

      PubDate: Tue, 04 Nov 2014 10:31:02 GMT
  • The Most Influential Scientists in the Development of the Medical
           Informatics (2): Morris F. Collen

    • Abstract: 2014-11-13T08-33-20Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Fri, 31 Oct 2014 00:21:41 GMT
  • Identification of an Alternate Maxillary Apical Base Landmark from
           Pre-existing Substitutions

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Kunal S. Patel, Narayan Kulkarni, Varun Pratap Singh, Kartik Parikh.
      Background: Cephalometrically the position of maxilla is usually assessed by point A, which is one of the most common cephalometric landmarks used for spatial analysis of maxilla, however in certain scenarios we require a alternative landmark. Aims: In this study a nearest alternative maxillary apical base landmark was identified for Point A substitutions given by different authors. Methods and Material: A cross sectional study was conducted on thirty (30) good quality lateral cephalograms. Only those lateral cephalograms were selected where Point A was easily identified. Landmarks: Sella (S), Nasion (N), Point A and three substitution points Y, L, X were traced. Angles formed by SN with Point A (Angle SNA) and three substitution points (Angle SNY, SNX, SNL) were measured. Correlation of angle SNA with angles SNY, SNX and SNL were derived. Statistical analysis used: Results: Mean and standard deviation for Angles SNA, SNY, SNL and SNX were calculated individually for males and females. ‘T’ Test was applied to determine statistical significance for all the parameters i.e Age, Angles SNA, SNY, SNL and SNX respectively. Karl Pearson correlation coefficient was carried out to determine the statistical significant correlation for Angle SNA with SNY, SNL and SNX. Results: A mean value of 82.80 ±1.90, 83.10 ±1.80, 78.30 ±2.90 and 78.70 ±2.70 for Angle’s SNA, SNY, SNL and SNX respectively was observed. A statistically significant correlation was observed between angles SNA & SNY, SNL, SNX & strong positive correlation was observed with angle SNY. Conclusions: We conclude that Point Y is the most nearing maxillary apical base landmark to Point A. Hence maxillary apical base landmark can be substituted by Point Y where identification of point A is not obvious.

      PubDate: Wed, 29 Oct 2014 10:25:55 GMT
  • A Design Protocol to Develop Radiology Dashboards

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Mahtab Karami.
      Aim: The main objective of this descriptive and development research was to introduce a design protocol to develop radiology dashboards. Material and methods: The first step was to determine key performance indicators for radiology department. The second step was to determine required infrastructure for implementation of radiology dashboards. Infrastructure was extracted from both data and technology perspectives. The third step was to determine main features of the radiology dashboards. The fourth step was to determine the key criteria for evaluating the dashboards. In all these steps, non-probability sampling methods including convenience and purposive were employed and sample size determined based on a persuasion model. Results: Results showed that there are 92 KPIs, 10 main features for designing dashboards and 53 key criteria for dashboards evaluation. As well as, a Prototype of radiology management dashboards in four aspects including services, clients, personnel and cost-income were implemented and evaluated. Applying such dashboards could help managers to enhance performance, productivity and quality of services in radiology department.

      PubDate: Wed, 29 Oct 2014 10:23:46 GMT
  • Outcome of Endovenous Laser Ablation of Varicose Veins

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Nedzad Rustempasic, Alemko Cvorak, Alija Agincic.
      Introduction: In Bosnia and Herzegovina according to available data, treatment of incompetent superficial lower extremity varicose veins by endovenous laser ablation (EVLA) has been introduced two years ago and so far no paper has been published regarding results of EVLA treatment of patients from our country. We wanted to present our results with EVLA treatment. Aim of study: to evaluate and compare primary posttreatment outcomes of endovenous laser ablation (EVLA) with classical surgical method of varicose vein treatment. Patients and methods: The study was clinical and prospective. It was carried out at Clinic for vascular surgery in Sarajevo where fifty-eight (58) patients received surgical treatment for varicose veins and in Aesthetic Surgery Center “ Nasa mala klinika“ in Sarajevo were sixty-one (61) patients with varicose veins were treated by endovenous laser ablation. Total 119 patients (limbs) with pathologic reflux only in great saphenous vein were evaluated between 1st of January 2013 and 31st of April 2014. Following primary outcome endpoints were evaluated: mean day of return to normal everyday activities, patient subjective quantification of pain during first seven days after intervention, incidence of deep venous thrombosis (DVT), incidence of wound bleeding requiring surgical intervention, incidence of peri-saphenous vein hematoma and infection rate. Results: Mean of return to normal activities (expressed in days after intervention); EVLA vs. stripping (surgery) =1.21vs12.24, T test 13,619; p=0, 000, p0,05 , respectively.) Conclusion: EVLA offers better patient recovery in terms of significantly lower post treatment pain, faster return to everyday activities and lower incidence of bruising (hematomas).

      PubDate: Wed, 29 Oct 2014 10:20:39 GMT
  • Organizational Factors that Affect the Implementation of Information
           Technology: Perspectives of Middle Managers in Iran

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hosein Barzekar, Mahtab Karami.
      Objective: to examine the organizational factors affecting the application of information technology in hospitals. Since the organizational factors are one of the most important determinants of successful projects, by understanding their impact and identifying them it can help planning a systematic IT implementation. Methods: In this cross-sectional descriptive study 110 middle managers were chosen from teaching hospitals. Structured questionnaire was used for the data collection. Results: There was a significant relationship between organization resource, organizational knowledge, process, management structure and values and goals with implementation of information technology. Conclusion: Findings showed that organizational factors had a considerable impact on implementation of information technology. Top managers must consider the important aspects of effective organizational factors.

      PubDate: Wed, 29 Oct 2014 10:19:27 GMT
  • Survey Determinant Factors of Telemedicine Strategic Planning from the
           Managers and Experts Perspective in the Health Department, Isfahan
           University of Medical Sciences

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hamid Keshvari, Asefeh Haddadpoor, Behjat Taheri, Mehran Nasri, Pezhman Aghdak.
      Introduction: Awareness of Outlook, objectives, benefits and impact of telemedicine technology that can promote services quality, reduce costs, increase access to Specialized and subspecialty services, and immediately guide the health system subconsciously to the introduction greater use of technology. Therefore, the aim of this study was to determine the strengths, weaknesses, opportunities and threats in the telemedicine strategic planning from the managers and experts perspective in the health department, Isfahan University of Medical Sciences, in order to take a step towards facilitating strategic planning and approaching the equity aim in health in the province. Method: This is a descriptive–analytical study, that data collection was done cross-sectional. The study population was composed of all managers and certified experts at the health department in Isfahan university of Medical Sciences. The sample size was 60 patients according to inclusion criteria. Information was collected by interview method. Researcher attempted to use the structured and specific questionnaire Then were investigated the viewpoints of experts and managers about determinative factors (strengths, weaknesses, opportunities and threats) in the strategic planning telemedicine. Data were analyzed using descriptive statistics (frequency, mean) and software SPSS 19. Results: Data analysis showed that change management (100%) and continuity of supply of credit (79/3%) were weakness point within the organization and strengths of the program were, identity and health telemedicine programs (100%), goals and aspirations of the current directors of the organization and its compliance with the goals of telemedicine (100%), human resources interested using computers in daily activities in peripheral levels (93/1%). Also organization in the field of IT professionals, had opportunities, and repayment specialist’s rights by insurance organizations is a threat for it. Conclusions: According to the strengths, weaknesses, opportunities and threats points determined by managers and experts, and compare it with success and failure factors, which are defined by different researchers, it seems will be fail to implement of telemedicine in the province at present. But according to the strengths identified by managers and experts, there are a lot of potential for telemedicine in the province, and may be used, in relation to telemedicine projects, with a 3 or 5 year strategic plan, and taking steps to get closer to the equity aim in health.

      PubDate: Wed, 29 Oct 2014 10:18:17 GMT
  • Telemetric Detection of Chronic Obstructive Pulmonary Disease and
           Investigation of Quality of Life for People Working in Shipbuilding

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Agoritsa Koulouri, Konstantinos Gourgoulianis, Chryssi Hatzoglou, Zoe Roupa.
      Introduction: Chronic Obstructive Pulmonary Disease (COPD) has a significant impact on quality of life-related health. Aim: It was the detection of Chronic Obstructive Pulmonary Disease by using telemetric methods and the investigation of the quality of life for people working in Shipbuilding Industry compared with a control group. Methods: A group of one hundred men working in the shipbuilding industry aged 51.8 ± 8.2 years old and a control group of one hundred men of the general population aged 51.1 ± 6.4 years were studied. All participants completed the General Health Questionnaire – 28, the Fagerstrom test and a form with demographic characteristics. Pulmonary function test results were electronically sent to a specialist for evaluation. Results: People working in the shipbuilding zone had significantly lower values (p

      PubDate: Wed, 29 Oct 2014 10:16:47 GMT
  • Evaluation of Extracorporeal Shock Wave Lithotripsy (ESWL): Efficacy in
           Treatment of Urinary System Stones

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Dzelaludin Junuzovic, Jelena Kovacevic Prstojevic, Munira Hasanbegovic, Zahid Lepara.
      Introduction: Elimination of stone is determined by size and its localization. Stone from the ureter in 80% of cases can be eliminated spontaneously. If the stone by its characteristics is not spontaneously eliminated, taken are further steps and therapeutic protocols to solve this problem. Material and methods: The study was prospective, open and comparative. It was conducted at the Urology Clinic Clinical Center of Sarajevo University in the period from 2007 to 2013. The study included 404 patients with urinary tract lithiasis treated by ESWL. ESWL treatment is performed on the machine Siemens Model Lithostar Multiline, which has a combined ultrasonographic and fluoroscopic display, large energy density in order to obtain optimum focus (without damaging surrounding tissue) and minimal pain that on rare occasions requires for mild sedation-sedation. Results: From a total of 404 patients included in the study there were 234 (57.92%) male and 170 (42.08%) female patients. The most common type of stone both in female and male patients was calcium type. From a total of 262 calcium stones, 105 of them (40.07%) was present in female patients and 157 (59.92%) in male. Share of infectious type of stone in female patients was 63 (49.60%) and 64 among males (50.39%). Other stones were less abundant in both the gender groups and their total number was only 17. In women their frequency was 2 (13.33%) and 13 among males (86.67%). There was a significant difference in the frequency of different types of stones by gender (χ2 = 11.47, p = 0.009). Conclusion: There was no statistically significant correlation between the number of treatments and localization of stones in the ureter, as well as a statistically significant correlation between the size of the stone and the localization of calculus in the ureter.

      PubDate: Wed, 29 Oct 2014 10:14:36 GMT
  • Ultrasound Measurement of Cervical Length as Predictor of Threatened
           Preterm Birth: a Predictive Model

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Mohammad Abou El-Ardat, Fatima Gavrankapetanovic, Khalil A. Abou El-Ardat, Sanjin Dekovic, Senad Murtezic, EldarMehmedbasic, Nadja Hiros.
      Introduction: The incidence of preterm delivery has been increasing even in developed countries and remains a serious problem for fetuses and neonates. Although many predictors for preterm delivery have been proposed, complete prediction and prevention have not yet been established. Aims: To examine the potential association between sonographic measurement of cervical length and threatened preterm birth (TPTB) in pregnant woman at 24-36 weeks of gestation. Materials and methods: A cross-sectional study included a total of 360 pregnant woman at 24-36 weeks of gestation categorized in two groups: TPTB group (n=160) and non TPTB group (n=200). The study was carried out at the Department of Obstetrics and Gynecology of the Clinical Center University of Sarajevo (KCUS). Sociodemographic and clinical characteristics of patients were obtained from medical records and physical examination by gynecologist. Transvaginal sonography was carried out by GE Voluson 730. Results: There was a significant association between TPTB and sonographic measurement of cervical length

      PubDate: Wed, 29 Oct 2014 10:13:13 GMT
  • Preoperative Kidney Tumor Embolization as Procedure for Therapy of
           Advanced Kidney Cancer

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Suad Jaganjac, L. Schefe, Edin Avdagi&#;, Hajrudin Spahovi&#;, Mustafa Hiros.
      Introduction: Preoperative kidney tumor embolization is standard procedure for therapy in advanced kidney cancer. Preoperative embolization has a goal to reduce intraoperative bleeding and also to shorten the time of surgery. Materials and methods: We retrospectively observed 50 patients between 2000-2011, in which the preoperative embolization was performed. Mean age of patients was 64 years. All patients with preoperative embolization were compared with the group of 51 patients from Urology Sarajevo, who underwent nephrectomy without preoperative embolization. Results: Symptoms that are dominating among patients were haematuria and pain. Analysis of mean size of tumors based on CT evaluation showed statistically significance in between the biggest size of tumors in group from Hamburg( 9.11±3cm) and the smallest size of tumors in Sarajevo group (4.94±1.6cm) p=0.0001. Reason for this is difference in selection of patients for treatment in Hamburg from Sarajevo. Conclusion: Kidney as functional finishing organ is extremely suitable for transcatheter therapeutic procedures. The gold standard in the treatment of advanced and metastatic tumor is the nephrectomy. As preparation for nephrectomy in metastatic cancer total capillary embolization is performed. After embolization, surgery is shorter, procedure can be done 24-48 hours after embolization or delayed nephrectomy done 2-3 weeks after the intervention.

      PubDate: Wed, 29 Oct 2014 10:12:04 GMT
  • Back Pain in Children and Diagnostic Value of 99mTc MDP Bone Scintigraphy

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Khaled Alkhawaldeh, Ali AL Ghuweri, Jane Kawar, Amany Jaafreh.
      Aim: The aim of our study is to assess the diagnostic value of Technituim-99m-Methyle diphosphonate (99mTc-MDP) Bone scintigraphy in the assessment of children with back pain. Methods: Included in this retrospective study were 68 child referred to us complaining of back pain (mean age of 13+ 2). There were 45 boys and 23 girls. All children have been investigated with conventional x-ray which revealed normal or inconclusive result. All underwent bone scintigraphy after the injection of 99mTc-MDP with calculated doses according to there body weights. Results: Bone scintigraphy revealed 17 (25%) abnormal scans in 11 boys and 6 girls. Scans findings were suggestive of spondylolysis (n=4); malignancy including primary tumors and metastases (n=3); infection including osteomyelitis and discitis (n=3); sacroiliitis (n=2); benign tumors (n=2); pseudo fractures in ribs (n=1); necrosis in femoral head epiphysis(n=1) and nonskeletal- renal retention due to hydronephrosis (n=1). Sensitivity, specificity and accuracy of bone scan in detecting gross skeletal abnormality as a cause for back pain were 94% and 100% and 99% respectively. Conclusion: Bone isotope scan is a sensitive imaging modality in the assessment of pediatric patients with back pain. It is a reliable modality to detect and role out most benign and aggressive serious etiologies.

      PubDate: Wed, 29 Oct 2014 10:10:32 GMT
  • The Perceptions of Professionalism by 1st and 5th Grade Medical Students

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zalika Klemenc-Ketis,, Helena Vrecko.
      Introduction: Professionalism is essential for the development of mature physicians but not much education is devoted to that theme. Aim: We aimed to determine the views of undergraduate medical students on medical professionalism. Methods: This was a qualitative study, based on focus groups of the first and fifth-year undergraduate medical students. Transcripts of the focus groups were independently evaluated by two researches. Segments of transcripts, identified as important, were marked as verbatims. A grounded theory method with open coding was applied. A list of codes was developed and reviewed by both researchers until the consensus was reached. Then, the codes were reviewed and put into the categories and dimensions. Results: Students recognized 10 main medical professionalism dimensions (empathy, respect, responsibility, autonomy, trust, communication, difference between professional and private life, team work, partnership) and two dimensions associated with it (physician’s characteristics, external factors). Slight change of the attitudes towards a more self-centred future physicians’ figure was observed in the fifth-year medical students. Conclusion: The students have an appropriate picture of the physicians’ figure even at the beginning of their medical studies but still needs an education in professionalism. It seems that the fifth-year students perceive physicians as more self-centred when compared to their first-year colleagues.

      PubDate: Wed, 29 Oct 2014 10:09:02 GMT
  • Intelligent Data Analysis: the Best Approach for Chronic Heart Failure
           (CHF) Follow Up Management

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Niloofar Mohammadzadeh, Reza Safdari, Alireza Baraani, Farshid Mohammadzadeh.
      Objective: Intelligent data analysis has ability to prepare and present complex relations between symptoms and diseases, medical and treatment consequences and definitely has significant role in improving follow-up management of chronic heart failure (CHF) patients, increasing speed ​​and accuracy in diagnosis and treatments; reducing costs, designing and implementation of clinical guidelines. The aim: The aim of this article is to describe intelligent data analysis methods in order to improve patient monitoring in follow and treatment of chronic heart failure patients as the best approach for CHF follow up management. Methods: Minimum data set (MDS) requirements for monitoring and follow up of CHF patient designed in checklist with six main parts. All CHF patients that discharged in 2013 from Tehran heart center have been selected. The MDS for monitoring CHF patient status were collected during 5 months in three different times of follow up. Gathered data was imported in RAPIDMINER 5 software. Results: Modeling was based on decision trees methods such as C4.5, CHAID, ID3 and k-Nearest Neighbors algorithm (K-NN) with k=1. Final analysis was based on voting method. Decision trees and K-NN evaluate according to Cross-Validation. Conclusion: Creating and using standard terminologies and databases consistent with these terminologies help to meet the challenges related to data collection from various places and data application in intelligent data analysis. It should be noted that intelligent analysis of health data and intelligent system can never replace cardiologists. It can only act as a helpful tool for the cardiologist’s decisions making.

      PubDate: Tue, 14 Oct 2014 04:46:28 GMT
  • Correlation Between the Findings of Optical Coherent Retinal Tomography
           (OCT), Stereo Biomicroscopic Images from Fundus of an Eye and Values from
           Visual Acuity of Diabetic Macular Edema

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Faruk Nisic, Samir Turkovic, Milka Mavija, Nina Jovanovic, Emina Halilovic-Alimanovic.
      Introduction: Diabetic maculopathy is the major cause of reduced visual acuity in patients with non-proliferative diabetic retinopathy and occurs on average in 29% of patients who have diabetes for 20 or more years. The aim: The aim of this study is to re examine the correlation between the findings of optical coherence retinal tomography, stereo biomicroscopic images from fundus of an eye and values from visual acuity of diabetic macular edema. In addition, the aim is to show the importance of various ophthalmic tests for establishing diagnosis in time. Material and methods: The research sample consisted of 90 subjects-patients from Cabinet for photographic documentation, fluorescein angiography and laser photocoagulation in Department of Ophthalmology at the University Clinical Centre in Sarajevo. The study was a one-year long, prospective, clinical and manipulative. Results: Research has shown a positive correlation between the various tests that are applied for the diagnosis of diabetic macular edema. Accurate and early diagnosis is of great importance for the treatment in time of this disease by applying laser photocoagulation, intravitreal injections of Anti-VEGF drugs or surgical treatment by Pars Plana Vitrectomy.

      PubDate: Mon, 08 Sep 2014 22:59:35 GMT
  • The Most Influential Scientists in Development of Medical Informatics (1)

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic.

      PubDate: Thu, 21 Aug 2014 11:55:32 GMT
  • Critical Thinking: The Development of an Essential Skill for Nursing

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Ioanna V. Papathanasiou, Christos F. Kleisiaris, Evangelos C. Fradelos, Katerina Kakou, Lambrini Kourkouta.
      Critical thinking is defined as the mental process of actively and skillfully perception, analysis, synthesis and evaluation of collected information through observation, experience and communication that leads to a decision for action. In nursing education there is frequent reference to critical thinking and to the significance that it has in daily clinical nursing practice. Nursing clinical instructors know that students face difficulties in making decisions related to clinical practice. The main critical thinking skills in which nursing students should be exercised during their studies are critical analysis, introductory and concluding justification, valid conclusion, distinguish of facts and opinions, evaluation the credibility of information sources, clarification of concepts and recognition of conditions. Specific behaviors are essentials for enhancing critical thinking. Nursing students in order to learn and apply critical thinking should develop independence of thought, fairness, perspicacity in personal and social level, humility, spiritual courage, integrity, perseverance, self-confidence, interest for research and curiosity. Critical thinking is an essential process for the safe, efficient and skillful nursing practice. The nursing education programs should adopt attitudes that promote critical thinking and mobilize the skills of critical reasoning.

      PubDate: Thu, 21 Aug 2014 11:54:36 GMT
  • Telemedicine in Gastroenterohepatology

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Muharem Zildzic, Nizama Salihefendic, Ferid Krupic, Emina Beganovic, Lejla Zunic, Izet Masic.
      Telemedicine itself is not the medical profession, it is not a medical specialty, but the way in which the medical profession conduct its activity. Therefore we are talking about tele otorhinolaryngology, tele cardiology or tele pathology. In the definition of a multitude of telemedicine that can be found in the literature is the following: Telemedicine is a system that supports the process of health care by providing ways and means for more efficient exchange of information that allows multitude of activities related to health care, including health care and health personnel, including education, administration and treatment. Telemedicine applications include: tele diagnosis, tele consultation, tele monitoring, tele-care, tele consultations and remote access to information contained in one or more databases. It turned out that telemedicine is an important factor in technological, professional, financial and organizational uniformity of development of the health system. Telemedicine, although a new area, to a large extent already changed the ways of providing health care, and even more influence on the ways of designing the future of medicine.

      PubDate: Thu, 21 Aug 2014 11:53:08 GMT
  • The Status of Hospital Information Systems in Iranian Hospitals

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Maryam Jahanbakhsh, Mohammed Sharifi, Masar Ayat.
      Background: The area of e-Health is broad and has an excellent growth potential. An increasing number of experts believe that e-Health will fuel the next breakthroughs in health system improvements throughout the world, but there is frequent evidence of unsustainable use of e-Health systems in medical centres, particularly hospitals, for different reasons in different countries. Iran is also a developing country which is presently adopting this promising technology for its traditional healthcare delivery but there is not much information about the use of e-Health systems in its hospitals, and the weakness and opportunities of utilization of such Hospital Information Systems (HIS). Methods: For this research, a number of Hospitals from Isfahan, Iran, are selected using convenient sampling. E-health research professionals went there to observe their HIS and collect required data as a qualitative survey. The design of interview questions was based on the researchers’ experiences and knowledge in this area along with elementary interviews with experts on HIS utilization in hospitals. Results: Efficient administration of e-health implementation improves the quality of healthcare, reduces costs and medical errors, makes healthcare resources available to rural areas, etc. However, there are numerous issues affecting the successful utilization of e-health in Hospitals, such as a lack of a perfect HIS implementation plan and well-defined strategy, inadequate IT-security for the protection of e-health-related data, improper training and educational issues, legal challenges, privacy concerns, improper documentation of lessons learned, resistance to the application of new technologies, and finally a lack of recovery plan and disaster management. These results along with some informative stories are extracted from interview sessions to uncover associated challenges of HIS utilization in Iranian hospitals. Conclusion: The utilization of e-health in Iranian hospitals, particularly those in Isfahan, is subject to several challenges and there is no proper long-term strategy plans for HIS initiation, development, and improvement in Iranian hospitals. In order to address these problems, six recommendations are provided. Hence, human resource and e-health professionals from third party consultancy companies along with medical university scholars have to assist such hospitals to undertake the proposed solutions in order to provide proper plans to overcome future challenges and have a mature HIS in accordance with expected HIS utilization from hospitals and medical universities.

      PubDate: Thu, 21 Aug 2014 11:51:02 GMT
  • Bibliometric Analysis of Stem Cell Publications in Iran

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Shafi Habibi, Maryam Ahmadi, Shahram Sedghi, Fateme Hosseini.
      Objective: The purpose of this study is to examine qualitative and quantitative states of stem cell research in Iran in order to extract information production patterns. Methods: The data were extracted by searching through the Science Citation Index (SCI) Expanded database related to January 2013. The number of published articles and frequency of their citation were used as indices of the quality and quantity of information production. Results: Total number of Iranian stem cell articles and proceedings indexed in Web of Science until 2012 was 709. The highest frequency belonged to the multiple institution category (45-50% of the articles during 2005-2012). The highest CPP rate (29.7) belonged to the international articles written by the authors from other countries with Iranian coauthors. Conclusion: Although cooperation between more authors from different institutions and countries can increase the quality of scientific articles, results of this research showed that international research must be distinguished in terms of author sequence.

      PubDate: Thu, 21 Aug 2014 11:47:38 GMT
  • Evaluation of the Scientific Outputs of Researchers with Similar H Index:
           a Critical Approach

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hemmat Gholinia Ahangar,, Hasan Siamian, Mousa Yaminfirooz.
      Background and Purpose: h-index has been always reviewed as one of the most useful criteria for evaluating the scientific outputs of researchers by the sciencometric experts. In this study, the h-index of 40 Iranian researchers accompanied with its relationship to assessment criteria of scientific outputs such as the number of articles, scientific age, number of citations and self-citation were reviewed. Materials and Methods: The first part of this study was related to the literature review. But the information of 40 Iranian researchers’ Citation Reports was observational extracted from WOS database and the Pearson correlation coefficient test was used to answer the research hypotheses. Results: Citation analysis showed that 40 selected researchers published 877 articles in web of science up to 9 January 2013. These articles have been cited 3858 time. The average of their h-index was estimated 38.5 ±12.12 Correlation coefficient test showed that there was a significant and direct relationship between the h-index and the number of papers, the number of citations and self-citation (Sig>0.05) but there was no significant relationship between scientific age and h-index (Sig> 0.05). Conclusions: Analysis of the data showed that the quantitative and qualitative indicators of the researchers with the same h-index had considerable differences. Therefore, only the h-index should not be a criterion for scientific ranking of the researchers and other complementary indexes such as M parameter and G index along with h-index must be used to be able to more accurately determine the degree of scientific influence of the researchers with the same h.

      PubDate: Thu, 21 Aug 2014 11:46:25 GMT
  • Genomics Analysis of Replicative Helicase DnaB Sequences in Proteobacteria

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Silvana Poggi, Sathees B. Chandra.
      Replicative Helicase DnaB interacts with DnaA, DnaC, DnaG, and DNA polymerase III to commence replication, increase the movement rate of the replication fork, and to assemble part of the primosome. The formation of the replication fork is limited by the ability to load DnaB to the DNA, thus DnaB has shown to be vital to a large extent. In the absence of DnaB, the replication fork is not maintained and in a state of inactivity the replication fork degrades and collapses. To further understand importance of this enzyme from an evolutionary perspective, a genomic analysis DnaB protein sequences, chosen from five Proteobacteria subclasses was performed. Our analysis indicates that, DnaB replicative helicases of Alphaproteobacteria and Epsilonproteobacteria have diverged at an earlier stage from Betaproteobacteria, Deltaproteobacteria and Gammaproteobacteria as well as from one another. Our results were further supported, when we reanalyzed and reconstructed the phylogenetic tree after the inclusion of sequences from Actinobacteria and Firmicute phylum. In addition, Betaproteobacteria, Deltaproteobacteria, and Gammaproteobacteria appear to share a closer common ancestor than from the other two subclasses. The Dot-plot analysis indicated that, the region between amino acid residues 320 to 400 was strongly conserved among all five subclasses.

      PubDate: Thu, 21 Aug 2014 11:44:41 GMT
  • A HTK-based Method for Detecting Vocal Fold Pathology

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Vahid Majidnezhad.
      Introduction: In recent years a number of methods based on acoustic analysis were developed for vocal fold pathology detection. These methods can be categorized in two categories: a) detection based on the phonemes b) detection based on the continuous speeches. While there are many researches which belong to the first category, there are few efforts for detecting vocal fold pathology based on the continuous speeches (second category). Methods: In this work, a method based on the Hidden Markov model Toolkit (HTK) for detecting vocal fold pathology in the Russian digits is developed which belongs to the second category. It employs a three state HMM for modeling each phoneme. Results: According to the results of the experiments, the proposed method achieves the 90% of detection accuracy. Conclusion: The proposed method is one of the first works for detecting vocal fold pathology based on the Russian digits (from 1 to 10) for Belorussian people. The reported accuracy is rather good and therefore it is recommended to use it as an auxiliary tool in medical centers.

      PubDate: Thu, 21 Aug 2014 11:42:31 GMT
  • Analysis of the Abfraction Lesions Formation Mechanism by the Finite
           Element Method

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Selma Jakupovic, Edin Cerjakovic, Alan Topcic, Muhamed Ajanovic, Alma Konjhodzic-Prcic, Amra Vukovic.
      Introduction: An abfraction lesion is a type of a non-carious cervical lesion (NCCL) that represents a sharp defect on the cervical part of tooth, caused by occlusal biomechanical forces. The largest prevalence of the NCCL is found on the mandibular first premolar. The goal of the study is, by means of a numerical method – the finite element method (FEM), in an appropriate computer program, conduct a stress analysis of the mandibular premolar under various static loads, with a special reference to the biomechanics of cervical tooth region. Material and methods: A three-dimensional model of the mandibular premolar is gained from a µCT x-ray image. By using the FEM, straining of the enamel, dentin, peridontal ligament and alveolar bone under axial and paraxial forces of 200 [N] is analyzed. The following software were used in the analysis: CT images processing–CTAn program and FEM analysis–AnsysWorkbench 14.0. Results: According to results obtained through the FEM method, the calculated stress is higher with eccentric forces within all tested tooth tissue. The occlusal load leads to a significant stress in the cervical tooth area, especially in the sub-superficial layer of the enamel (over 50 MPa). The measured stress in the peridontal ligament is approximately three times higher under paraxial load with regard to the axial load, while stress calculated in the alveolar bone under paraxial load is almost ten times higher with regard to the axial load. The highest stress values were calculated in the cervical part of the alveoli, where bone resorption is most commonly seen. Conclusion: Action of occlusal forces, especially paraxial ones, leads to significant stress in the cervical part of tooth. The stress values in the cervical sub-superficial enamel layer are almost 5 times higher in relation to the superficial enamel, which additionally confirms complexity of biomechanical processes in the creation of abfraction lesions.

      PubDate: Thu, 21 Aug 2014 11:41:18 GMT
  • Predictive Values of Optical Coherence Tomography (OCT) Parameters in
           Assessment of Glaucoma progression

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Sanja Sefic Kasumovic, Aida Kasumovic, Suzana Pavljasevic, Emir Cabric, Milka Mavija, Irena Sesar, Sabina Dacic-Lepara, Mirko Jankov.
      Goal: the purpose of the current study was to estimate the predictive values of optical coherence tomography parameters in early, developed perimetric and terminal glaucoma. Methods: 180 eyes of 120 consecutive patients were evaluated in this retrospective cross sectional pilot study. Copernicus Spectral –domain optical coherence tomography with resolution of 3 mm obtained throught the optic nerve head were included. All examined eyes were divided to four groups (healthy,early, developed perimetric glaucoma and terminal glaucoma). The values of the thicknes of the retinal nerve fibre layer, the size of the disk, the volume of the cup, the E/D parameter and the size of the RIM were compared in four study groups. Results:The sensitivity of RNFL was 90,0%, specificity 82,0 %, positive predictability 83,3 % and negative predictability was 89,1 %. The total accuracy was 86,0 % and area under curve (AUC) was 0,878 for RNFL indeks compering early to developed glaucoma. The sensitivity for CUP was 78%, the specificity was 80,8 %, the positive predictability 81,2% and the negative predictability was 77,5 %. The total accuracy was 79,3 % and area under curve (AUC) was 0,86 compering early to developed glaucoma. The sensitivity for E/D was 82,0%, the specificity was 82,9 % the positive predictability 83,7 % and the negative predictability was 81,3 %. The total accuracy was 82,5 % and area under curve (AUC) for E/D was 0,89 compering eearly to developed glaucoma.The sensitivity for RIM was 78,0%, the specificity was 76,6 %, the positive predictability was 84,7 and the negative predictability was 67,7 %. The total accuracy was 77,5 % and area under curve (AUC) for the RIM compering the developed to terminal glaucoma was 0,792. The sensitivity of RNFL was 88,0 %, the specificity was 66,7 %, the positive predictability was 81,5% and the negative predictability was 76,9%. The total accuracy was 80,0% and the area under curve (AUC) for RNFL compering developed to terminal glaucoma was 0,815. The incrreasing 0,1 unit RNFL decreases the risk of developing glaucoma from early to another developed stage of glaucoma for 6,95%. The increasing of E/D for only one unit increases the risk to develop another stage of glaucoma for 18,75 times. The increasing of RNFL for only one unit decreases the risk of performing developed glaucoma from initial stage for 7,8%. The increasing for only one unit of CUP increases the risk to develop terminal glaucoma for 8,47 times and increasing for 0,1 unit of the value of RIM decreases the risk developing terminal glaucoma for 9,27%. The increasing for 0,01 unit of the E/D index increases the risk for terminal glaucoma for 23,23 times. The increasing for one unit of RNFL decreasing the risk developing terminal glaucoma for 5,7%.

      PubDate: Thu, 21 Aug 2014 11:39:52 GMT
  • Information Technologies in Education of Medical Students at the
           University of Sarajevo

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Izet Masic, Emina Karcic, Ajla Hodzic, Smaila Mulic.
      Introduction: Information and communication technology have brought about many changes in medical education and practice, especially in the field of diagnostics. During the academic year 2013/2014, at Faculty of Medicine, University of Sarajevo, students in the final year of the study were subjected to examination which aim was to determine how medical students in Bosnia and Herzegovina subjectively assessing their skills for using computers, have gained insight into the nature of Information Technology’s (IT) education and possessive knowledge. Material and methods: The survey was conducted voluntary by anonymous questionnaire consisting of 27 questions, divided into five categories, which are collecting facts about student’s: sex, age, year of entry, computer skills, possessing the same, the use of the Internet, the method of obtaining currently knowledge and recommendations of students in order to improve their IT training. Results of the study: According to the given parameters, indicate an obvious difference in the level of knowledge, use and practical application of Information Technology’s knowledge among students of the Bologna process to the students educated under the old system in favor of the first ones. Based on a comparison of similar studies conducted in Croatia, Sri Lanka, Pakistan and Denmark, it was observed that the level of knowledge of students of the Medical Faculty in Sarajevo was of equal height or greater than in these countries.

      PubDate: Thu, 21 Aug 2014 11:36:29 GMT
  • EASE Guidelines for Authors and Translators of Scientific Articles to be
           Published in English

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      European Association of Science Editors (EASE).
      This concise and readable set of editorial guidelines was first published by the European Association of Science Editors (EASE) in 2010 and is updated annually. It is freely available in more than 20 languages at The document is aimed to help scientists worldwide in successful presentation of their research results and in correct translation of manuscripts into English. Moreover, it draws attention to ethical issues, like authorship criteria, plagiarism, conflict of interests, etc. Eight appendices provide examples or more detailed information on selected topics (Abstracts, Ambiguity, Cohesion, Ethics, Plurals, Simplicity, Spelling, and Text-tables). Widespread use of EASE Guidelines should increase the efficiency of international scientific communication.

      PubDate: Sun, 15 Jun 2014 10:43:47 GMT
  • The Use of Smart phones in Ophthalmology

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Edita Zvornicanin, Jasmin Zvornicanin, Bahrudin Hadziefendic.
      Smart phones are being increasingly used among health professionals. Ophthalmological applications are widely available and can turn smart phones into sophisticated medical devices. Smart phones can be useful instruments for the practice of evidence-based medicine, professional education, mobile clinical communication, patient education, disease self-management, remote patient monitoring or as powerful administrative tools. Several applications are available for different ophthalmological examinations that can assess visual acuity, color vision, astigmatism, pupil size, Amsler grid test and more. Smart phones can be useful ophthalmic devices for taking images of anterior and posterior eye segment. Professional literature and educational material for patients are easily available with use of smart phones. Smart phones can store great amount of informations and are useful for long term monitoring with caution for patient confidentiality. The use of smart phones especially as diagnostic tools is not standardized and results should be carefully considered. Innovative role of smartphone technology and its use in research, education and information sharing makes smart phones a future of ophthalmology and medicine.

      PubDate: Sun, 15 Jun 2014 10:42:16 GMT
  • Changes in the Muscle Strength of the Elbow Flexors Following a Six-week
           Experimental Procedure in Adolescents Monitored Through Isokinetic and
           Motor Tests

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Vladimir Vuksanovic, Zoran Handjiski, Eli Handjiska.
      A group of 7 subjects underwent an experimental procedure which studied the potential changes in the maximal strength of the non-dominant arm elbow flexors. The programme duration was limited to 6 weeks during which the subjects practiced exercises 3 times a week, 3 series, on a Scott bench. Individual approach was applied to the external load and it was designed so that the weight being lifted would increase if the number of lifts in one series would exceed 3. The subjects were monitored through the one-repetition maximum 1 RM motor test and the isokinetic tests performed on biodex system, tested in 3 time periods (at the beginning, after 3 weeks, and after the 6th week). Of the 6 isokinetic tests, only the test for the maximum torque and the time for achieving the maximum torque have shown statistically important changes in terms of reduction in values, which was not expected. The one-repetition maximum test, unlike the isokinetic tests, has shown statistically important increase of the maximal muscle strength of 32.1% after the third week of exercising, and 46.8% after the six weeks of exercising. The statistical test for the correlation between the two variables has shown low correlation between these two tests. The values of the data of the two test types have not shown any correspondence among the subjects possibly due to the type of performance of the maximal muscle load during exercises, performed in conditions identical to the one-repetition maximum test, with similar and yet different conditions in the case of isokinetic tests. Most probably, due to the conditions in which the exercises and the tests took place, there is difference in the obtained results.

      PubDate: Sun, 15 Jun 2014 10:40:33 GMT
  • Contribution of Indian Pediatric Dentists to Scientific Literature During
           2002–2012: a Bibliometric Analysis

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jatinder Kaur Dhillon, Namrata C Gill.
      Introduction: Bibliometric analysis of publications is necessary to enable clinicians to make evidence based sound clinical decisions. It will also help policy makers & institutions to frame their decisions and policies so as to improve the quality of dental research in India. AIM: The purpose of this study is to identify publication output as well as descriptively and quantitatively characterize the contribution of Indian pediatric dentists to scientific literature through publication trend analysis from 2002 to 2012. Settings and design: Cross sectional analytical study. Material and method: A bibliometric analysis of publications by Indian pediatric dentists during 2002 to 2012 was performed on data collected from PubMed – MEDLINE database. Only the first author’s affiliations were considered and the publications were categorized according to the following variables: year of publication, number of authors, state of origin, type of article, reach of journal and country of publication. Results: There were 817 articles by Indian pediatric dentists during the study period. Of all the articles 399 (48.8%) were original research, 377(46.1%) were case reports and 41 (5.0%) were reviews. The inter-annual variation between the reach, country of publication of the journal and type of articles is presented. The growth trend analysis was performed and predictions are presented. Conclusion: There has been an increase in the number of publications by Indian pediatric dentists and most of the published work comprises of original research. The potential use of this data is discussed.

      PubDate: Sun, 15 Jun 2014 10:38:47 GMT
  • Scientific production of Sports Science in Iran: A Scientometric Analysis

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Mousa Yaminfirooz, Hasan Siamian, Mohammad Ali Jahani, Masoud Yaminifirouz.
      Background: Physical education and sports science is one of the branches of humanities. The purpose of this study is determining the quantitative and qualitative rate of progress in scientific Production of Iran’s researcher in Web of Science. Methods: Research Methods is Scientometric survey and Statistical Society Includes 233 Documents From 1993 to 2012 are indexed in ISI. Results: Results showed that the time of this study, Iranian researchers’ published 233 documents in this base during this period of time which has been cited 1106(4.76 times on average). The H- index has also been 17. Iran’s most scientific productions in sports science realm was indexed in 2010 with 57 documents and the least in 2000. Conclusions: By considering the numbers of citations and the obtained H- index, it can be said that the quality of Iranian’s articles is rather acceptable but in comparison to prestigious universities and large number of professors and university students in this field, the quantity of outputted articles is very low.

      PubDate: Sun, 15 Jun 2014 10:35:45 GMT
  • Medical Universities Educational and Research Online Services:
           Benchmarking Universities’ Website Towards E-Government

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Mehrdad Farzandipour, Zahra Meidani.
      Background: Websites as one of the initial steps towards an e-government adoption do facilitate delivery of online and customer-oriented services. In this study we intended to investigate the role of the websites of medical universities in providing educational and research services following the E-government maturity model in the Iranian universities. Methods: This descriptive and cross- sectional study was conducted through content analysis and benchmarking the websites in 2012. The research population included the entire medical university website (37). Delivery of educational and research services through these university websites including information, interaction, transaction, and Integration were investigated using a checklist. The data were then analyzed by means of descriptive statistics and using SPSS software. Results: Level of educational and research services by websites of the medical universities type I and II was evaluated medium as 1.99 and 1.89, respectively. All the universities gained a mean score of 1 out of 3 in terms of integration of educational and research services. Conclusions: Results of the study indicated that Iranian universities have passed information and interaction stages, but they have not made much progress in transaction and integration stages. Failure to adapt to e-government in Iranian medical universities in which limiting factors such as users’ e-literacy, access to the internet and ICT infrastructure are not so crucial as in other organizations, suggest that e-government realization goes beyond technical challenges.

      PubDate: Sun, 15 Jun 2014 10:34:23 GMT
  • Quality Assessment of Persian Mental Disorders Websites Using the
           Webmedqual Scale

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Leila Shahrzadi, Shahin Mojiri, Sima Janatian, Behjat Taheri, Hasan Ashrafi-rizi, Zeinab Shahrzadi, Razieh Zahedi.
      Introduction: Nowadays, anyone with any level of Internet knowledge can act as producer and distributor of information. It differs from most traditional media of information transmission, lack of information control and lack of quality management to contents. This leads to quality of health information on the internet is doubtful. The object of this study is guidance patients to select valid mental disorders and determine the quality of Persian mental disorders websites. Methods: The sample of this study comprised 29 Persian mental disorders websites that were chosen by searching the Google, Yahoo and AltaVista search engines for the Persian equivalents of the three concepts “depression,” “anxiety,” and “obsession”. website was created by individuals or organizations. Data collection was performed with the WebMedQual checklist. Websites was assessed based on indicators as content, authority of source, design, accessibility and availability, links, user support, and confidentiality and privacy (Maximum score for any website was 83, mean score 41.5 and minimum score was 0). Collected data analyzed by one sample T- test in SPSS 20. Findings presented by Mean score and optimal score. Results: Based on the WebMedQual scale the mean score of Persian mental disorders websites in sex constructs including “content” (7.02±2.10), “authority of source” (4.71±1.96),“accessibility and availability” (2.19±0.47), “links” (1.45±0.97), “user support” (4.28±1.33), and“confidentiality and privacy” (2.81±2.81) are poor and below average, but the score for the “design” (9.17± 1.59) is above average. The best website of mental disorders was that of the “IranianPsychological Association”. Conclusions: According to the results, only one website obtained the average score, so the quality of Persian mental disorders websites is low. Therefore, it is essential for users to criticize websites’ content and not trust them before evaluating them. It is better to use the ranked list websites or search on the internet by help information experts.

      PubDate: Sun, 15 Jun 2014 10:32:47 GMT
  • A Survey on the Users’ Satisfaction with the Hospital Information
           Systems (HISs) based on DeLone and McLean’s Model in the
           Medical-Teaching Hospitals in Isfahan City

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Sakineh Saghaeiannejad-Isfahani, Maryam Jahanbakhsh, Mahboobeh Habibi, Razieh Mirzaeian, Mansoreh Nasirian, Javad Sharifi Rad.
      Background and purpose: The user’s satisfaction with information system in fact denotes the extent the user is satisfied with the system’s achievement in fulfilling his/her information requirements. This study tries to explore the users’ satisfaction with hospital information systems (HISs) based on DeLone and McLean’s model focusing on the medical-teaching hospitals of Isfahan city. Methodology: This study which was applied and descriptive-analytical in nature was carried out in the medical-teaching hospitals of Isfahan city in 2009. Research population consisted of the system users from which a sample was selected using random sampling method. The size of the sample was 228. Data collection instrument was a self-developed questionnaire produced based on the satisfaction criterion in the DeLone and McLean’s model. Its content validity was assessed based on the opinions given by the computer sciences professionals with its estimated Cronbach’s alpha found to be 92.2%. The data were analyzed using SPSS software. Findings: As the findings of the study showed, the differences among the mean scores obtained for the satisfaction with different kinds of HISs in use in the hospitals were statistically significant (p value≤0.05). Generally, Kowsar System (old version) and Pouya Samaneh Diva system gained the highest and lowest mean scores for the criterion in question, respectively. The overall mean score for the satisfaction was 54.6% for different types of systems and 55.6% among the hospitals. Conclusion: Given the findings of the study, it can be argued that based on the used model, the level of users’ satisfaction with the systems in question was relatively good. However, to achieve the total optimum condition, when designing the system, the factors affecting the enhancement of the users’ satisfaction and the type of hospital activity and specialty must be given special consideration.

      PubDate: Sun, 15 Jun 2014 10:31:22 GMT
  • Importance of Alpha-adrenergic Receptor Subtypes in Regulating of Airways
           Tonus at Patients with Bronchial Asthma

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Pellumb Islami, Ali Ilazi, Arianit Jakupi, Sadi Bexheti, Hilmi Islami.
      Background: In this work, effect of Tamsulosin hydrochloride as antagonist of alpha1A and alpha1B- adrenergic receptor and effect of Salbutamol as agonist of beta2- adrenergic receptor in patients with bronchial asthma and increased bronchial reactibility was studied. Methods: Parameters of the lung function are determined by Body plethysmography. Raw and ITGV were registered and specific resistance (SRaw) was also calculated. Tamsulosin was administered in per os way as a preparation in the form of the capsules with a brand name of “Prolosin”, producer: Niche Generics Limited, Hitchin, Herts. Results: Results gained from this research show that blockage of alpha1A and alpha1B- adrenergic receptor with Tamsulosin hydrochloride (0.4 mg and 0.8 mg in per os way) has not changed significantly (p> 0.1) the bronchomotor tonus of tracheobronchial tree in comparison to the inhalation of Salbutamol as agonist of beta2- adrenergic receptor (2 inh. x 0.2 mg), (p < 0.05). Arterial blood pressure showed no significant decrease following the administration of the dose of 0.8 mg Tamsulosin. Conclusion: This suggests that the activity of alpha1A and alpha1B- adrenergic receptor in the smooth musculature is not a primary mechanism which causes reaction in patients with increased bronchial reactibility, in comparison to agonists of beta2 – adrenergic receptor which emphasizes their significant action in the reduction of specific resistance of airways.

      PubDate: Sun, 15 Jun 2014 10:30:12 GMT
  • Potential Role of Lung Ventilation Scintigraphy in the Assessment of COPD

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Vesna Cukic, Amela Begic.
      Objective: To highlight the importance of the lung ventilation scintigraphy (LVS ) to study the regional distribution of lung ventilation and to describe most frequent abnormal patterns of lung ventilation distribution obtained by this technique in COPD and to compare the information obtained by LVS with the that obtained by traditional lung function tests. Material and methods: The research was done in 20 patients with previously diagnosed COPD who were treated in Intensive care unit of Clinic for pulmonary diseases and TB “Podhrastovi” Clinical Center, University of Sarajevo in exacerbation of COPD during first three months of 2014. Each patient was undergone to testing of pulmonary function by body plethysmography and ventilation/perfusion lung scintigraphy with radio pharmaceutics Technegas, 111 MBq Tc -99m-MAA. We compared the results obtained by these two methods. Results: All patients with COPD have a damaged lung function tests examined by body plethysmography implying airflow obstruction, but LVS indicates not only airflow obstruction and reduced ventilation, but also indicates the disorders in distribution in lung ventilation. Conclusion: LVS may add further information to the functional evaluation of COPD to that provided by traditional lung function tests and may contribute to characterizing the different phenotypes of COPD.

      PubDate: Sun, 15 Jun 2014 10:28:37 GMT
  • Endoscopic Management of Vesicoureteral Reflux in Children in Kosova

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Murat Berisha, Nexhmi Hyseni, Sejdi Statovci, Salih Grajqevci, Butrint Xhiha.
      Introduction: Vesicoureteral reflux (VUR) in children has been treated with subureteric deflux injection of Deflux (dextranomer hyaluronic acid copolymer) since 2009. The aim of this study was to analyze the results of endoscopic treatment of VUR in our clinic. Methods: Between March 2009 and December 2013, fifty-five children underwent endoscopic subureteral injection of Deflux in 78 ureters. Two months postoperatively voiding cystourethrogram (VCUG) was performed. This study examined the disappearance of VUR and urinary tract infection (UTI) as well as the quality of life during long-term follow-up. Results: The study included 55 patients (40 females and 15 males) with 78 refluxing ureters. There were 22 refluxed ureters altogether and 33 children had a unilateral reflux (two duplicated systems). All patients were treated, from the age 6 months up to 12 years old. The mean age of patients was 5.2 years. There has been no complications, but with few recurrences. In 6 patients (16.6%), endoscopic treatment with deflux was done twice, while in three patients (8.5%), the endoscopic treatment with deflux was performed three times, because of recurrence. Conclusion: We recommend the use of endoscopic Deflux injection as first line treatment for children with VUR .Endoscopic subureteral injection of Deflux is a minimally invasive method for VUR treatment in pediatric patients and is associated with low morbidity.

      PubDate: Sun, 15 Jun 2014 10:27:05 GMT
  • Colonoscopy as a Method of Choice in the Diagnosis of Colorectal Cancer

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Sead Buturovic.
      Introduction: Epidemiological characteristics of colorectal cancer indicate that in the U.S. colorectal cancer is the second leading cause of death from malignancy, just behind lung cancer. In the 2000 there were approximately 130,200 new cases, of which 56,300 had lethal outcome. In the past 15 years, the incidence and mortality rate has been declining, especially in women. Colorectal cancer is mainly found in people older than 50 years. Carcinoembryonic antigen (CEA) is insufficiently specific for the early detection of the disease. Its normal value is less than 5 g/L in the serum. Elevated levels of CEA after surgery indicate a lack of radical surgery, residual neoplasm, hidden distant metastases or recurrent disease. Unfortunately, only 10-15% of patients with recurrent disease can be successfully re-operated (isolated metastases in the liver or lungs). Colorectal cancer is predominantly adenocarcinoma, the tumor has relatively slow growth. While symptoms occur relatively early, distant metastases have relatively late appearance. Goals: The goals of this study were to remind the fundamental facts about the nature of this disease, to stress the importance of early detection of BC-screening programs, to draw attention to contemporary attitudes in the field of diagnosis and treatment of colorectal cancer, and to show the experience in the treatment of this disease at the Surgical Departments of the General Hospital in Konjic. Results: In the period from 2008-2012 years, at the Surgical Department of the General Hospital in Konjic surgically treated are 34 patients who had colorectal malignancy. There were 21 (65 %) male and 13 females (35%). All patients belonged to the age group of 50-75 years. Only five patients or 15 % prior to admission to the hospital had been diagnosed with a malignant process. All others, or 85% of the total sample, were admitted to the hospital as emergency cases (erosive gastritis), and after, shorter preparation underwent surgery. Only five (15%) of patients were admitted electively, already diagnosed with colorectal tumors by colonoscopy. Total number of lethal outcomes at the department was 8 (24%). Three patients died due to cardio-respiratory failure and MOF, and 5 patients due to anastomotic failure and septic shock. Conclusion: In conclusion we can say that in our institution it is necessary to obtain the proper equipment (colonoscope) and educate personnel, so we can introduce colonoscopy as the mandatory screening method of examination, particularly for vulnerable groups.

      PubDate: Sun, 15 Jun 2014 10:25:31 GMT
  • Sensitivity of EUS and ERCP Endoscopic Procedures in the Detection of
           Pancreatic Cancer During Preoperative Staging Correlated with CT and CT
           Angiography Imaging Methods

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zora Vukobrat-Bijedic, Azra Husic-Selimovic, Nina Bijedic, Srdjan Gornjakovic, Amela Sofic, Bisera Gogov, Ivana Bjelogrlic, Amila Mehmedovic, Sanjin Glavas.
      The goal: The goal of this work was to give advantage to EUS as endoscopic method in diagnosis and following therapeutic treatment of pancreatic cancer in relation to radiological methods of CT and CTA. Material and Methods: The study included 49 patients, 20 women and 29 men hospitalized at the Clinic for gastroenterohepatology, due to suspicion on pancreatic cancer during observed 2 years period. All cancers were histologically and cytologically confirmed. The patients underwent ERCP as a mandatory part of staging and all patients underwent endoscopic ultrasound as well as CT or CT angiography. Results: Testing of differences was carried out using Fisher’s exact test in open-source software R. The following characteristics were tested: involvement of the blood vessels, lymph nodes, metastases, tumor size and duodenum infiltration. Results showed statistically significant difference at the 0.05 level for EUS, CT and CT angiography. Risk ratio showed that EUS is less effective in detecting infiltration of blood vessels within a malignant process then CTA where RR=0.52, CI 0.2–1.38, p-value=0.33. EUS and CTA are equal in the diagnosis of enlarged lymph nodes affected by malignancy where RR=1.3, CI 0.75–1.42, p-value=0.09. Comparison according to distant metastases showed that EUS is less effective compared to CT in approximately 30% of cases. In the diagnosis of duodenal infiltration EUS is in 5% of cases less accurate than the CT with the RR=0.95, CI 0.27–3.32, p-value=0.76, but the CTA method is more efficient because the comparison of EUS and CTA showed RR=12.52, CI 0.2–1.38, p-value=0.33. EUS as a diagnostic method is dominant in determining the size of malignant lesions located in the pancreas as compared to CT and CTA. Conclusion: EUS as endoscopic method compared to CT and CTA is one of the more invasive methods of examination but due to its ability to be performed immediately, to locate a changes smaller than 5 mm and the target biopsy option, to measure the change and that in many cases determine the relationship of malignant lesions with blood vessels, along with visualization of the surrounding lymph nodes and metastases in neighboring organs, we may give this method an advantage over other methods in the preoperative staging of patients with pancreatic cancer.

      PubDate: Sun, 15 Jun 2014 10:24:07 GMT
  • Effect of Initial Conditions on Reproducibility of Scientific Research

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Benjamin Djulbegovic,, Iztok Hozo.
      Background: It is estimated that about half of currently published research cannot be reproduced. Many reasons have been offered as explanations for failure to reproduce scientific research findings- from fraud to the issues related to design, conduct, analysis, or publishing scientific research. We also postulate a sensitive dependency on initial conditions by which small changes can result in the large differences in the research findings when attempted to be reproduced at later times. Methods: We employed a simple logistic regression equation to model the effect of covariates on the initial study findings. We then fed the input from the logistic equation into a logistic map function to model stability of the results in repeated experiments over time. We illustrate the approach by modeling effects of different factors on the choice of correct treatment. Results: We found that reproducibility of the study findings depended both on the initial values of all independent variables and the rate of change in the baseline conditions, the latter being more important. When the changes in the baseline conditions vary by about 3.5 to about 4 in between experiments, no research findings could be reproduced. However, when the rate of change between the experiments is ≤2.5 the results become highly predictable between the experiments. Conclusions: Many results cannot be reproduced because of the changes in the initial conditions between the experiments. Better control of the baseline conditions in-between the experiments may help improve reproducibility of scientific findings.

      PubDate: Sun, 15 Jun 2014 10:22:48 GMT
  • My View on Plagiarism

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Ermin Begovic.

      PubDate: Mon, 17 Mar 2014 12:33:11 GMT
  • Spinal Dissemination of Intracranial Glioblastoma in Bevacizumab Era: a
           Potential Bevacizumab-induced Mechanism

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Gentian Kaloshi, Arben Roji, Arsen Seferi, Bujar Cakani, Teona Bushati, Ermir Roci, Mentor Petrela.
      Spinal metastasis, a devastating neurologic complication of intracranial glioblastomas is not as uncommon as initially thought. It varies from 25% in supratentorial glioblastomas to 60% in infratentorial glioblastomas. The underlying pathogenesis spinal spread of high-grade gliomas is still unclear. To date, no causal responsibility of Bevacizumab (BEV) was noted. Here, we report for the first time, a case of thoracic intramedullary metastases from a cerebral glioblastoma pre-treated with BEV. A critical and exhaustive review is provided.

      PubDate: Mon, 17 Mar 2014 12:30:04 GMT
  • Use of the Toric Intraocular Lens for Keratoconus Treatment

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Jasmin Zvornicanin, Emir Cabric, Vahid Jusufovic, Zlatko Musanovic, Edita Zvornicanin.
      A 50 year old man presented to Eye clinic University clinical centre Tuzla with bilateral visual impairment. Clinical examination revealed low visual acuity and keratoconus in both eyes, white cataract in right eye and diabetic retinopathy in left eye. Ultrasonography examination was normal. The patient underwent Trypan blue capsule staining, phacoemulsification and implantation of intraocular lens Alcon AcrySof SN60T9 16 D spherical and 6.0 D cylinder power. Phacoemulsification went uneventful and early postoperative recovery was successful. Visual acuity improved to 0,8 and fundus examination revealed background diabetic retinopathy. Postoperative follow up two years after surgery showed no signs of keratoconus progression and visual acuity maintained the same.

      PubDate: Mon, 17 Mar 2014 12:27:41 GMT
  • A Roadmap to Pre-Implementation of Electronic Health Record: the Key Step
           to Success

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Marjan Ghazisaeidi, Maryam Ahmadi, Farahnaz Sadoughi, Reza Safdari.
      Introduction: Initial attempts are made to implement electronic health record (EHR) in Iran, the present study aim is developing a proper roadmap to EHR in pre-implementation phase by expert views on the matter. Method: An initial framework was developed for pre- implementation based on reviewing literature on EHR implementation and descriptive-comparative with qualitative approaches in five countries. A questionnaire was designed in several sections using 47 main topics associated with pre-implementation. Cronbach’s alpha 0.89 confirmed the reliability of the data. Expert views were used to score each topic based on Likert scale and opinions were collected through Delphi. Then results analyzed using descriptive statistical analysis method. Result: Framework of EHR pre-implementation roadmap was presented in four phases: preliminaries, assessment, planning, and method of choosing system vendors. Priorities in each part were determined and reflected in the roadmap using expert views, analyses, and requirements of each phase. It seems strategic planning at different levels; assessment of needs; providing and managing financial resources, setting standards; examining the existing condition was determined as highest priorities in above phases. Conclusion: For successful implementation, developing national carefully-designed and well-documented EHR pre-implementing roadmap, Based on country situation, from strategic to operation level is necessary.

      PubDate: Mon, 17 Mar 2014 12:25:11 GMT
  • Cervical Length Measured by Transvaginal Ultrasonography and
           Cervicovaginal Infection as Predictor of Preterm Birth Risk

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Arnela Ceric Banicevic, Miroslav Popovic, Amela Ceric.
      Introduction: The study shows possibilities of transvaginal sonographic measurement of the cervix in prediction of premature birth risk. Goals: The aim of the study was to follow up the cervical length in the pregnant from 16th to 37th week, as well as to do a microbiological analysis of the vaginal and cervical flora and to identify relation between the cervical shortening and microbiological flora as well as with a premature birth. Material and methods: The investigation was conducted as a prospective study on two groups of female patients in Clinical Centre of Banja Luka. In the high risk group we had 8% of patients with cervical length bellow than 15mm, 30% of patients with cervical length from 15 to 25m and 62% of patients with cervical length bigger than 25mm. In the low risk group we had no patients with cervical length bellow 15mm, 95% of patients had cervical length bigger than 25mm and 5% of patients had cervical length from 15 do 25mm. Results: The regression coefficient of the cervical length in the high risk group was 0.44mm, while in the low risk group it was 0.26mm. In the high risk group 67.56% patients had a positive cervical smear finding, while in the low risk group it was 4%. A high premature birth (defined as birth before 36.6 weeks) incidence of 50% was presented in patients with cervical length bellow 15mm. In the group of patients with cervical length up to 25mm the premature risk incidence was 10.52±0.05. In the high risk group of patients with a positive cervical smear finding, regarding the cervical length the percentage was as follows; in the subgroup of 15mm length 88,89±11,87, in subgroup from 15 to 25mm was 62,07±11,43 and in the subgroup bigger than 25mm, 60.06±8.05. Conclusion: By the analysis of the first and second goal of our study we can conclude that ultrasound assessment of cervical length is simple and feasible in the 16th week of pregnancy in both groups, with high and low risk. The length of the cervix in this period is shorter in the high risk group compared with the low-risk group. This difference was not statistically significant, however, it clearly demonstrated connection between shorten length of the cervix with the preterm birth. A regression analysis shows that the shortening of the cervix length is more frequent in high risk group which is to be expected, bearing in mind that in this group, the risk of preterm delivery was significantly higher.

      PubDate: Mon, 17 Mar 2014 12:22:17 GMT
  • Experiences of Academic Members About their Professional Challenges: a
           Content Analysis Qualitative Study

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Zohreh Shahhosseini, Mahmonier Danesh.
      Background: University faculty members of different disciplines in any country, by giving better quality services, will further accelerate the development of their respective countries. This study aims to explore the experiences of faculty members about their professional challenges. Aim: In this qualitative study, which was conducted in 2013, fifteen faculty members in the departments of clinical and basic sciences of Mazandaran university of Medical Sciences in northern Iran were chosen for semi-structured in-depth interviews by purposive sampling method. All tape-recorded data were fully transcribed and content analysis was performed. Results: After immersion and data analysis, three main themes were emerged including: “Imbalances in academic members’ tasks in different areas”, “Weakness of evaluation and promotion system” and “Failure to provide the infrastructure educational facilities”. The main themes and sub-themes are explained by the help of participants’ direct quotations. Conclusions: This study suggested that it is better to take effective measures to improve the faculty members’ situation and therefore increase their efficiency, effectiveness and productivity.

      PubDate: Mon, 17 Mar 2014 12:20:49 GMT
  • Proposed Use of the Computer as a Tool to Aid Analysis of Properties of
           Materials in Fixators of Spine

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Antonio Santos, Fernando Moreira.
      With objective of analyzing the mechanical behavior of the internal fixators of spine and of the bony structure, the pieces and the group were made (it structures bony x internal fixator) with the aid a software of solid modeling. The materials used in the rehearsals had been the titanium, now in the market and a castor oil polyurethane destined to the development of you implant bony.

      PubDate: Mon, 17 Mar 2014 12:16:37 GMT
  • A Comparative Study of the Proposed Models for the Components of the
           National Health Information System

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Maryam Ahmadi, Shahla Damanabi, Farahnaz Sadoughi.
      Introduction: National Health Information System plays an important role in ensuring timely and reliable access to Health information, which is essential for strategic and operational decisions that improve health, quality and effectiveness of health care. In other words, using the National Health information system you can improve the quality of health data, information and knowledge used to support decision making at all levels and areas of the health sector. Since full identification of the components of this system – for better planning and management influential factors of performance- seems necessary, therefore, in this study different attitudes towards components of this system are explored comparatively. Methods: This is a descriptive and comparative kind of study. The society includes printed and electronic documents containing components of the national health information system in three parts: input, process and output. In this context, search for information using library resources and internet search were conducted, and data analysis was expressed using comparative tables and qualitative data. Results: The findings showed that there are three different perspectives presenting the components of national health information system - Lippeveld and Sauerborn and Bodart model in 2000, Health Metrics Network (HMN) model from World Health Organization in 2008, and Gattini’s 2009 model. All three models outlined above in the input (resources and structure) require components of management and leadership, planning and design programs, supply of staff, software and hardware facilities and equipment. Plus, in the ‘’process’’ section from three models, we pointed up the actions ensuring the quality of health information system, and in output section, except for Lippeveld Model, two other models consider information products and use and distribution of information as components of the national health information system. Conclusion: the results showed that all the three models have had a brief discussion about the components of health information in input section. But Lippeveld model has overlooked the components of national health information in process and output sections. Therefore, it seems that the health measurement model of network has a comprehensive presentation for the components of health system in all three sections-input, process and output.

      PubDate: Mon, 17 Mar 2014 12:15:21 GMT
  • Reliability Assessment of Arthroscopic Findings Versus MRI in ACL Injuries
           of the Knee

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hristijan Kostov, Stojmenski Slavcho, Elena Kostova.
      Introduction: This study was conducted to analyze the reliability of clinical diagnosis in ACL tear injuries. Material and methods: All patients attending our clinic with knee pain from 2009 to 2013 underwent systematic and thorough clinical assessment. From one hundred and three patients with knee problems in 73 were arhroscopicaly diagnosed ACL tears. All these patients underwent therapeutic arthroscopic knee surgery. The clinical diagnosis was confirmed during this procedure. The accuracy, sensitivity and specificity were calculated based on these arthroscopic findings. Results: The accuracy of clinical diagnosis in our study was 82.5% for ACL tears. Our study revealed high sensitivity and specificity and almost high accuracy for ACL injuries of knee joint in comparison to arthroscopy. MRI is an appropriate screening tool for therapeutic arthroscopy, making diagnostic arthroscopy unnecessary in most patients. Conclusion: Magnetic resonance imaging is accurate and non invasive modality for the assessment of ligamentous injuries. It can be used as a first line investigation in patients with soft tissue trauma to knee.

      PubDate: Mon, 17 Mar 2014 12:13:55 GMT
  • Response of the Adrenergic System After Provoked Bronchoconstriction in
           Patients with Bronchial Asthma

    • Abstract: Publication year: 2014
      Source:Acta Informatica Medica
      Hilmi Islami, Ali Ilazi, Nijazi Gashi, Lirim Mustafa, Halit Maloku, Adelina Jashanica.
      Objective: In this paper, effect of the Tolazoline as antagonist of the alpha-2 adrenergic receptors in patients with bronchial asthma and chronic obstructive bronchitis was studied, and also the effect of stimulation with Hexoprenaline of beta-2 adrenergic receptor after bronchi-constriction caused with Propranolol, and Acetylcholine. Methods: Lung function parameters are determined with Body plethysmography. In patients with bronchial asthma and chronic obstructive bronchitis was registered resistance (Raw), was determined the amount of intrathoracic gas volume (ITGV), and specific resistance was calculated as well (SRaw). Aerosolization was done with standard aerosolizing machine–Asema. Results: The study included a total of 21 patients. Two hours after the inhalation of Propranolol, in experimental group, it was applied the blocker of alpha-2 adrenergic receptors (Tolazoline 20 mg / ml with inhalator ways), which did not cause changes in bronchomotor tonus of tracheobronchial system (p> 1.0). Meanwhile, at the same patient, stimulation of beta-2 adrenergic receptor with Hexoprenaline (2 inh x 0.2 mg) is associated with a significant decrease of the specific resistance of airways (SRaw, p < 0.01). Control group results show that after bronchi-constriction caused by Propranolol–aerosol (20 mg / ml) in patients with bronchial asthma and chronic obstructive bronchitis, an increase of specific resistance in airways was caused (SRaw, p < 0.01), which confirms the presence of hyper-reactive bronco-constrictor effects intermediated by vagal ways. Two hours after Propranolol, inhaled Hexorenaline has blocked the action of Propranolol, but not entirely. Furthermore, two hours after acetylcholine-aerosol (1 mg /ml) was applied, inhaled Ipratropium (2 inh x 1 mg) has fully blocked the action of chemical bronchoconstrictor mediators, causing a decline of specific resistance in the airways (SRaw; p < 0.01). Conclusion: This suggests that primary mechanism, which would cause reaction in patients with increased bronchial reactibility, is prevalence of the cholinergic system over adrenergic one, and not the relationship in between alpha-2 and beta-2 adrenergic receptors.

      PubDate: Mon, 17 Mar 2014 12:11:57 GMT
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