for Journals by Title or ISSN
for Articles by Keywords
help
Followed Journals
Journal you Follow: 0
 
Sign Up to follow journals, search in your chosen journals and, optionally, receive Email Alerts when new issues of your Followed Journals are published.
Already have an account? Sign In to see the journals you follow.
Journal Cover Acta Informatica Medica
  [SJR: 0.217]   [H-I: 4]   [0 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
   Published by ScopeMed Homepage  [98 journals]
  • 14th International Conference on Informatics, Management and Technology in
           Healthcare, Athens, Greece, 1-3 July, 2016

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Sat, 16 Jul 2016 06:52:15 GMT
       
  • The Most Influential Scientists in the Development of Medical informatics
           (13): Margaret Belle Dayhoff

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Sat, 16 Jul 2016 06:49:57 GMT
       
  • Value of Positron Emission Tomography/Computed Tomography (PET-CT) in
           Suspected Non-small Cell Lung Cancer Recurrence and Impact on Patient
           Management

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Nermina Beslic, Amera Sadija, Timur Ceric, Renata Milardovic, Sejla Ceric, and Semra Cavaljuga.
      Introduction: Positron emission tomography/computed tomography (PET-CT) is very sensitive for diagnosis of recurrent NSCLC and has a significant impact on change of management. Preliminary data suggest superiority of PET-CT comparing to CT alone for lung cancer restaging. Materials and methods: This is a retrospective study which aim is to validate usage of PET-CT in suspected non-small cell lung carcinoma recurrence and its impact on further patient management. Total number of 31 patients with non-small cell lung carcinoma and uncertain diagnosis of recurrent disease or its extent after routine clinical and CT work-up were enrolled in this study. Discussion: We found in our study that PET-CT diagnosed recurrent disease in 65% of patients who were previously presented with an indeterminante CT. In 85% of patients there were change in further management. Conclusion: We suggest that PET should be performed on patients who have suspected relapse after potentially curative treatment, particularly if active treatment is being considered. PET-CT improved the diagnosis of recurrent NSCLC and this resulted in a significant impact and change in further patient management.

      PubDate: Sat, 16 Jul 2016 06:48:55 GMT
       
  • Needs Assessment of Pathologists Using Telepathology Systems

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Sadrieh Hajesmaeel Gohari and Kambiz Bahaadinbeigy.
      Background: This project sought to identify the most common telepathology consultation needs of pathologists based on the anatomic section of tissue to improve quality of consultations. Methods: This cross-sectional study used a questionnaire with four questions to assess pathologists’ consultation needs. The questionnaire was distributed to the 16 pathologists recruited for this study. All 16 of the pathologists work in Kerman province, the largest province of Iran, which is situated 1,000 kilometers from Tehran, Iran’s capital city. Results: On average, the pathologists expressed a need to consult with their colleagues in 7.5% of cases. They believed that articular and bone tissue, soft tissue and the lymphoid system (respectively in descending order) to be the three anatomical parts that require the greatest amount of consultation. As such, consultant pathologists should ensure they have particular expertise in articular and bone tissue, soft tissue and the lymphoid system. Conclusion: This study demonstrated that pathologists most need advice from consultants when working with samples of articular and bone tissue, soft tissue and the lymphoid system. These results can be used to ensure successful implementation of telepathology systems, which are helpful for consultation from rural and remote areas.

      PubDate: Sat, 16 Jul 2016 06:47:39 GMT
       
  • Teleconsultation and Clinical Decision Making: a Systematic Review

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Kosloum Deldar, Kambiz Bahaadinbeigy, and Seyed Mahmood Tara.
      Background: The goal of teleconsultation is to omit geographical and functional distance between two or more geographically separated health care providers. The purpose of present study is to review and analyze physician-physician teleconsultations. Method: The PubMed electronic database was searched. The primary search was done on January 2015 and was updated on December 2015. A fetch and tag plan was designed by the researchers using an online Zotero library. Results: 174 full-text articles of 1702 records met inclusion criteria. Teleconsultation for pediatric patients accounts for 14.36 percent of accepted articles. Surgery and general medicine were the most prevalent medical fields in the adults and pediatrics, respectively. Most teleconsultations were inland experiences (no=135), and the USA, Italy and Australia were the three top countries in this group. Non-specialists health care providers/centers were the dominant group who requested teleconsultation (no=130). Real time, store and forward, and hybrid technologies were used in 50, 31, and 16.7 percent of articles, respectively. The teleconsultation were reported to result in change in treatment plan, referral or evacuation rate, change in diagnosis, educational effects, and rapid decision making. Use of structured or semi-structured template had been noticed only in a very few articles. Conclusion: The present study focused on the recent ten years of published articles on physician-physician teleconsultations. Our findings showed that although there are positive impacts of teleconsultation as improving patient management, still have gaps that need to be repaired.

      PubDate: Sat, 16 Jul 2016 06:46:34 GMT
       
  • Quantitative Assessment of Theses at Mazandaran University of Medical
           Sciences Years–(1995-2014)

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Azita Balaghafari, Hasan Siamian, Farideh Kharamin, Seyyedeh Shahrbanoo Rashida, and Nassim Ghahrani.
      Background: Review and evaluation of research for the correct steps towards real progress is essential which is a healthy and dynamic feature of the system. For the correct step toward real progress, evaluation research is essential which is feature of healthy and dynamic system. Considering the importance of scientific thesis in production and development and be aware of as the lack of structured information and qualitative and quantitative assessment at Mazandaran University of Medical Sciences, therefore we decided to do qualitative stud of theirs prepared 1995-2014. Methods: This study was a descriptive survey, a sample of 325 graduate and PhD thesis and dissertation in clinical and basic science at the university of medical sciences of the population in 2060 is a thesis from 1994 to the end of 2014. To study the population, stratified sampling method was used. The descriptive study was conducted in terms of matching the degree thesis students, theses subjects, specialty of supervisors and Advisers. The data gathering tool was checklist of information (gender, discipline, degree and department education of students, School, year of dependence, title of theses and dissertations, specialty and departments of supervisors and advisers, type of research, grade obtained of students). Statistical analysis of the data was performed using 21 SPSS software. Results: We studied 325 theses; 303 dissertations which 1 researcher; 21 dissertations which 2 researchers and 1 dissertation with 3 researchers. A total of 348 students (174 females and 174 males) researcher had theses. The number of students in the Department of Basic Science 82 (23.5%), 266 (76.5 %) in clinical group; 29(8.33%), 29 (8.33%) master degree; 260 (74.71%) general practitioner; 58 (16.67%) specialty and 1(29) at the PhD level. There was no relationship between research and level of education (p = 0.081). However, it was found that majority of the theses for the general practitioner (59.8%) wryer type 1(status condition). By matching and determining the overlapping of specialty of the advisor and the guide with the title, titles of the theses. It was found that 298 (91.69%) of the theses correspond with the specialty of the advisors and the supervisors. Conclusion: Based on the results obtained on the review of the theses to direct students to fundamental research and applying of specialized groups of supervisors and advisers in accordance with research is felt. No doubt that in the future will improve the quality of the students’ theses.

      PubDate: Sat, 16 Jul 2016 06:36:26 GMT
       
  • Organism Encumbrance of Cardiac Surgeon During Surgery

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Ilirijana Haxhibeqiri Karabdic, Fikret Veljovic, and Slavenka Straus.
      Introduction: Most everyday activities, performed over a long period leads to performance degradation of skeletal muscles as well as spinal column which is reflected in the reduction of maximum force, reduction of the speed of response, reducing control of the movement etc. Although until now many mathematical models of muscles are developed, very small number takes into account the fatigue, and those models that take into account changes in the characteristics of muscles for extended activities, generally considered tiring under certain conditions. Given that the current models of muscle fatigue under arbitrary conditions of activation and load are very limited, this article presents a new model that includes scale of muscles overload. Material and Methods: There are three female cardiac surgeons working performing these surgeries in operating rooms, and their average anthropometric measures for this population is: a) Weight: 62 kg; b) Height: 166 cm. Age: taken in the calculation within the CATIA software, that entity is entitled to 50% of healthy female population that is able to execute these and similar jobs. During the surgery is investigated the two most common positions: position “1” and “2”. We wish to emphasize that the experiment or surgical procedure lasted for two positions for five hours, with the position “1” lasted 0.5 hours, and position “2” lasted about 4.5 hours. The additional load arm during surgery is about 1.0 kg. Results: The analysis was done in three positions: “Operating position 1”, “Operating position 2 ‘, and each of these positions will be considered in its characteristic segments. These segments are: when the body takes the correct position, but is not yet burdened with external load, then when the surgeon receives the load and the third position when the load is lifted at the end of the position. Calculation of internal energy used on the joints is carried out in the context of software analysis of this model using CATIA R5v19. The proposed model is based on CATIA software model, which consists of visual indicators of the burden on certain parts of the body as well as the forces acting in these parts of the body. Conclusion: Based on these indicators to define which muscles, as well as that part of the skeletal system is overloaded, what is the position and what needs to be done that specific load be within permitted limits.

      PubDate: Sat, 16 Jul 2016 06:34:47 GMT
       
  • The Relation between Iranian Medical Science Research in PubMed and Burden
           of Disease

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Zahra Foroughi, Hasan Siamian, Reza Alizadeh-Navaei, and Ali Davodi.
      Introduction: Scientific productions have been accelerated in Iran in past decades but its association with health problems and disease burden is doubtful. The aim of this study is assessment of the relationship between scientific productions with disease burden in Iran in PubMed dataset during 2010 to 2014. Method: The study was performed with the library method. Data Gathered using Scientometrics indicators and direct observation. The current research includes all articles written by Iranian researchers during 2010 to 2014 which were published in PubMed–indexed journals. The search was performed using keywords included road accident, ischaemic heart diseases, major depression disorders and cerebral vascular diseases. Results: In total 910 articles had been published PubMed -indexed journals. Among them Substance-Related Disorders and Accidents, Traffic had the highest (263 records) and lowest (94 records) records respectively. There was not a direct correlation between Years of Life Lost, Years Lost due to Disability and mortality rate with scientific productions. Conclusions: our results showed Iranian scientific productions in PubMed data set are not related to disease burden however they are not related to high mortality diseases.

      PubDate: Sat, 16 Jul 2016 06:33:26 GMT
       
  • Designing and Implementation of Fuzzy Case-based Reasoning System on
           Android Platform Using Electronic Discharge Summary of Patients with
           Chronic Kidney Diseases

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Shahram Tahmasebian, Mostafa Langarizadeh, Marjan Ghazisaeidi, and Mitra Mahdavi-Mazdeh.
      Introduction: Case-based reasoning (CBR) systems are one of the effective methods to find the nearest solution to the current problems. These systems are used in various spheres as well as industry, business, and economy. The medical field is not an exception in this regard, and these systems are nowadays used in the various aspects of diagnosis and treatment. Methodology: In this study, the effective parameters were first extracted from the structured discharge summary prepared for patients with chronic kidney diseases based on data mining method. Then, through holding a meeting with experts in nephrology and using data mining methods, the weights of the parameters were extracted. Finally, fuzzy system has been employed in order to compare the similarities of current case and previous cases, and the system was implemented on the Android platform. Discussion: The data on electronic discharge records of patients with chronic kidney diseases were entered into the system. The measure of similarity was assessed using the algorithm provided in the system, and then compared with other known methods in CBR systems. Conclusion: Developing Clinical fuzzy CBR system used in Knowledge management framework for registering specific therapeutic methods , Knowledge sharing environment for experts in a specific domain and Powerful tools at the point of care .

      PubDate: Sat, 16 Jul 2016 06:31:58 GMT
       
  • Biomechanical Stability of Juvidur and Bone Models on Osteosyntesic
           Materials

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Predrag Grubor, Milorad Mitkovi&#;, Milan Grubor, Milan Mitkovi&#;, Luigi Meccariello, and Gabriele Falzarano.
      Introduction: Artificial models can be useful at approximate and qualitative research, which should give the preliminary results. Artificial models are usually made of photo-elastic plastic e.g.. juvidur, araldite in the three-dimensional contour shape of the bone. Anatomical preparations consist of the same heterogeneous, structural materials with extremely anisotropic and unequal highly elastic characteristics, which are embedded in a complex organic structure. The aim of the study: Examine the budget voltage and deformation of: dynamic compression plate (DCP), locking compression plate (LCP), Mitkovic internal fixator (MIF), Locked intramedullary nailing (LIN) on the compressive and bending forces on juvidur and veal bone models and compared the results of these two methods (juvidur, veal bone). Material and Methods: For the experimental study were used geometrically identical, anatomically shaped models of Juvidur and veal bones diameter of 30 mm and a length of 100 mm. Static tests were performed with SHIMADZU AGS-X testing machine, where the force of pressure (compression) increased from 0 N to 500 N, and then conducted relief. Bending forces grew from 0 N to 250 N, after which came into sharp relief. Results: On models of juvidur and veal bones studies have confirmed that uniform stability at the site of the fracture MIF with a coefficient ranking KMIF=0,1971, KLIN=0,2704, KDCP=0,2727 i KLCP=0,5821. Conclusion: On models of juvidur and veal bones working with Shimadzu AGS-X testing machine is best demonstrated MIF with a coefficient of 0.1971.

      PubDate: Sat, 16 Jul 2016 06:30:42 GMT
       
  • Efficacy of Multidetector-Row Computed Tomography as a Practical Tool in
           Comparison to Invasive Procedures for Visualization of the Biliary
           Obstruction

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Abdolmajid Taheri, Ayoob Rostamzadeh, Alireza Gharib and Daryoush Fatehi.
      Introduction: Recently, multidetector computed tomography (MDCT) has been introduced into clinical practice. MDCT has become the noninvasive diagnostic test of choice for detailed evaluation of biliary obstruction. Aim: the main objective of the present study was to evaluate the diagnostic value of MDCT compared to invasive procedures for detecting biliary obstruction causes. Material and Methods: Since February 2009 until May 2011 fifty biliary obstruction patients based on clinical, laboratory or ultrasonographic findings, were evaluated by Multidetector-row computed tomography. The causes of biliary obstruction, which was identified using MDCT were classified into three categories: calculus, benign stricture, and malignancy. Final diagnosis was conducted based on percutaneous transhepatic cholangiography (PTC), endoscopic retrograde cholangiopancreatography, biopsy, or surgery. The MDCT diagnosis and were compared with the final diagnosis. Results: A correct diagnosis of causes of biliaryobstruction was made on the basis of MDCT findings for 44 of the total 50 patients. Two patients with chronic pancreatitis were incorrectly diagnosed with a pancreatic head adenocarcinoma on the basis of MDCT findings. One patient with biliary stone was incorrectly diagnosed with a periampullary adenocarcinoma on the basis of MDCT findings. The Sensitivity, specificity and accuracy of MDCT in the diagnosis of causes of biliary obstruction were 94.12% and87.87% and94.6% respectively. Conclusion: Based on the findings of this study MDCT has an excellent image quality, providing valuable information about the biliary tree and other abdominal organs. The use of advanced image processing, including maximum intensity projection and multiplanar reconstruction (especially coronal or sagittal reformatted images), allows superior visualization of the biliary tree and vascular structures. Three-dimensional reconstruction images complement axial images by providing a more anatomically meaningful display of the lesion and its relationship to adjacent structures, and accurate determining the craniocaudal extent of the lesion. High accuracy, wide availability and ease of use, make the MDCT the imaging modality of choice for evaluation of biliary obstruction.

      PubDate: Sat, 16 Jul 2016 06:28:07 GMT
       
  • The Use of Continuous Electrocardiographic Holter Monitoring in Pediatric
           Cardiology

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Zijo Begic, Edin Begic, Senka Mesihovic-Dinarevic, Izet Masic, Senad Pesto, Mirza Halimic, Almira Kadic, and Amra Dobraca.
      Objective: To show the place and role of continuous electrocardiographic twenty-four-hour ECG monitoring in daily clinical practice of pediatric cardiologists. Methods: According to protocol, 2753 patients underwent dynamic continuous ECG Holter monitoring (data collected from the “Register of ECG Holter monitoring” of Pediatric Clinic, UCC Sarajevo in period April 2003- April 2015). Results: There were 50,5% boys and 49,5% girls, aged from birth to 19 years (1,63% - neonates and infants, 2,6% - toddlers, 9,95% - preschool children, 35,5% - gradeschoolers and 50,3% children in puberty and adolescence). In 68,1% of patients Holter was performed for the first time. Indications for conducting Holter were: arrhythmias in 42,2% cases, precordial pain in 23,5%, suspicion of pre-excitation and/or pre-excitation in 10%, crisis of consciousness in 8%, uncorrected congenital/acquired heart defects in 4,2%, operated heart defects in 3,7%, hypertension in 3,1% cases, control of the pacemaker in 1,63% and other causes in 3,5% cases. Discharge diagnosis after ECG Holter monitoring were: insignificant arrhythmias in 47,1% cases, wandering pacemaker in 21,3%, pre-excitation in 16,2%, benign ventricular premature beats in 6,3%, atrioventricular block in 3%, sinus pause in 2.2% cases and other arrhythmias in 3,5%. In mentioned period 57 cases of Wolf Parkinson White syndrome were registered, in 4,5% of patients antiarrhythmic therapy was administered. Radiofrequent ablation was performed in 23 cases. Conclusion: The development of pediatric cardiac surgery has initiated development of pediatric arrhythmology as imperative segment of pediatric cardiology. Continuous ECG Holter monitoring has become irreplaceable method in everyday diagnostics and therapy of arrhythmias in children.

      PubDate: Sat, 16 Jul 2016 06:26:54 GMT
       
  • Typing of Methicillin Resistant Staphylococcus Aureus Using DNA
           Fingerprints by Pulsed-field Gel Electrophoresis

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Velma Rebic, Ana Budimir, Mufida Aljicevic, Sabaheta Bektas, Sabina Mahmutovic Vranic, and Damir Rebic.
      Background: Methicillin resistant Staphylococcus aureus (MRSA) is responsible for a wide spectrum of nosocomial and community associated infections worldwide. The aim of this study was to analyze MRSA strains from the general population in Canton Sarajevo, B&H. Methods: Our investigation including either phenotypic and genotypic markers such as antimicrobial resistance, pulsed-field gel electrophoresis (PFGE), SCC typing, and Panton-Valentine leukocidin (PVL) detection. Results: Antimicrobial susceptibility: all MRSA isolates were resistant to the β-lactam antibiotics tested, and all isolates were susceptible trimethoprim sulphamethoxazole, rifampicin, fusidic acid, linezolid and vancomycin. Sixty-eight per cent of the MRSA isolates were resistant to erythromycin, 5% to clindamycin, 5% to gentamicin and 4% to ciprofloxacin. After the PFGE analysis, the isolates were grouped into five similarity groups: A-E. The largest number of isolates belonged to one of two groups: C: 60 (60%) and D: 27 (27%). In both groups C and D, SCCmec type IV was predominant (60% and 88, 8%, respectively). A total of 24% of the isolates had positive expression of PVL genes, while 76% showed a statistically significantly greater negative expression of PVL genes. Conclusion: SCCmec type IV, together with the susceptibility profile and PFGE grouping, is considered to be typical of CA-MRSA

      PubDate: Sat, 16 Jul 2016 06:25:46 GMT
       
  • DWI/ADC in Differentiation of Benign from Malignant Focal Liver Lesion

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Elma Jahic, Amela Sofic, and Azra Husic Selimovic.
      Material and methods: The study was of prospective-retrospective character. It was carried out at the AKH in Vienna (Austria), where 100 patients with focal liver lesions were included in the study. All patients underwent the routine MR sequences on appliances 1,5 and 3T (Siemens, Germany): T1, T2, HASTE, VIBE, and a DWI with three b values (b 50, b 300 b 600 s / mm 2) and ADC map with ROI (regions of interest). The numerical value of ADC map was calculated, where n = 100 liver lesions, by two independent radiologists. Results: On the basis of matching the PH finding statistically we get DWI accuracy of 96.8% for the assessment of liver lesions. The average numerical value of ADC in benign hepatic lesions (FNH, Hemangiomas) in our study amounted to 1.88 (1.326 to 2.48) x103 mm 2 /s, while the value of malignant liver lesions (HCC, CCC, CRCLM) were significantly lower and amounted to 1.15 (1.024 to 1.343) x10-3 mm 2 /s (Figure 2). Differences between the mean ADC of benign and malignant lesions showed a statistically significant difference with p

      PubDate: Sat, 16 Jul 2016 06:24:39 GMT
       
  • Calcitonin Receptor AluI (rs1801197) and Taq1 Calcitonin Genes
           Polymorphism in 45-and Over 45-year-old Women and their Association with
           Bone Density

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Morteza Dehghan, Razieh Pourahmad-Jaktaji, and Zarghampoor Farzaneh.
      Purpose: Calcitonin receptor gene has also a polymorphism which is associated with bone mass density. This study evaluates the association between calcitonin receptor AluI (rs1801197) and Taq1 calcitonin genes polymorphism with bone density rate. Methods: In this descriptive-analytical study in 2013 in southwestern Iran, 200 blood samples, per the Cochran sample size formula, were taken from women aged 45 and older. DNA was extracted from the samples using the phenol– chloroform method and the genomic fragments in question were proliferated using the polymerase chain reaction (PCR) method. Results: The genotypic distribution of polymorphism AluI for TT, TC, and CC genotypes in control group was 31.4%, 38.6%, and 30% and in patients 25.4%, 55.4%, and 19.2%, respectively. There was no significant difference in polymorphism AluI between patients and control group and no significant association was found between this gene and bone density rate (P> 0.05). All patients and the individuals in the control group exhibited tt genotype for TaqI calcitonin gene and no significant association was found between these participants and osteoporosis. Conclusion: There was no association between two polymorphisms and osteoporosis, and between polymorphism of these two genes and osteoporosis development rate in the participants.

      PubDate: Sat, 16 Jul 2016 06:21:59 GMT
       
  • Glycated Hemoglobin (HbA1c): Clinical Applications of a Mathematical
           Concept

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Melvin Khee Shing Leow.
      Background and purpose: Glycated hemoglobin (HbA1c) reflects the cumulative glucose exposure of erythrocytes over a preceding time frame proportional to erythrocyte survival. HbA1c is thus an areal function of the glucose-time curve, an educationally useful concept to aid teaching and clinical judgment. Methods: An ordinary differential equation is formulated as a parsimonious model of HbA1c. The integrated form yields HbA1c as an area-under-the-curve (AUC) of a glucose-time profile. The rate constant of the HbA1c model is then derived using the validated regression equation in the ADAG study that links mean blood glucose and HbA1c with a very high degree of goodness-of-fit. Results: This model has didactic utility to enable patients, biomedical students and clinicians to appreciate how HbA1c may be conceptually inferred from discrete blood glucose values using continuous glucose monitoring system (CGMS) or self-monitored blood glucose (SMBG) glucometer readings as shown in the examples. It can be appreciated how hypoglycemia can occur with rapid HbA1c decline despite poor glycemic control. Conclusions: Being independent of laboratory assay pitfalls, computed ‘virtual’ HbA1c serves as an invaluable internal consistency cross-check against laboratory-measured HbA1c discordant with SMBG readings suggestive of inaccurate/fraudulent glucometer records or hematologic disorders including thalassemia and hemoglobinopathy. This model could be implemented within portable glucometers, CGMS devices and even smartphone apps for deriving tentative ‘virtual’ HbA1c from serial glucose readings as an adjunct to measured HbA1c. Such predicted ‘virtual’ HbA1c readily accessible via glucometers may serve as feedback to modify behavior and empower diabetic patients to achieve better glycemic control.

      PubDate: Sat, 16 Jul 2016 06:20:09 GMT
       
  • Scientometric Dilemma: Is H-index Adequate for Scientific Validity of
           Academic’s Work'

    • Abstract: 2016-07-19T23-34-58Z
      Source: Acta Informatica Medica
      Izet Masic, Edin Begic.
      H-index is an index that attempts to measure the productivity and impact of published work of scientists. H-index has several advantages – it combines productivity with echo, is not sensitive to extreme values in terms of articles without citation or to articles with above-average number of citations and directly enables the identification of the most relevant articles with regard to the number of citations received. H-index has great potential in the academic community, but it still has not realistic indicator of the quality of work of one author.
      Authors described most used indices for scientific assessment.

      PubDate: Sat, 16 Jul 2016 06:19:00 GMT
       
  • The Most Influential Scientists in the Development of Medical informatics
           (12): Joshua Lederberg

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Fri, 03 Jun 2016 22:07:23 GMT
       
  • Ectopic Origin of Coronary Arteries Diagnozed by Coronary Angiography

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Xhevdet Krasniqi, Daut Gorani, Basri Sejdiu, Hajdin Citaku.
      Introduction: Anomalous origin of coronary arteries from opposite sinus of Valsalva is rare finding. The incidence of anomalous origination of the left coronary artery from right sinus is 0.15% and the right coronary artery from the left sinus is 0.92%. The ectopic origin of left coronary artery or right coronary artery from opposite sinus depending on pathways and considering atherosclerotic changes are manifested with different clinical significance. Case report: We report two cases, the first case the coronary angiography showed the left coronary artery arising from the right coronary sinus, presenting with proximally and distally stenosed left anterior descending artery (LAD), associated with medial and distal stenosed right coronary artery (RCA). The second case the coronary angiography revealed the right coronary artery arising from the left coronary sinus, associated with tortuous medial and distal segments of left anterior descending artery (LAD), without atherosclerotic changes. The first case successfully underwent treatment procedures based on guidelines for revascularization. Conclusion: The coronary angiography of patients with coronary ischemia determines atherosclerotic disease with possibility of the presence of coronary artery anomalies that in cases with ectopic origin from opposite sinus continues to exist as a challenge during treatment in interventional cardiology.

      PubDate: Fri, 03 Jun 2016 22:06:25 GMT
       
  • Radiological Findings of Michel Aplasia

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Ayse Umul, Hakan Demirtas, and Ahmet Orhan Celik.
      Introduction: Congenital abnormalities of the inner ear is the most common cause of neurosensory hearing loss. Michel inner ear deformity is a rare developmental anomaly refers to the total aplasia of the inner ear. It is caused by developmental arrest of otic placode early during the third week of gestational age. Case report: We have discussed here that three year old girl diagnosed Michel aplasia with temporal bone computed tomography (CT) and temporal magnetic resonance imaging (MRI) findings.

      PubDate: Fri, 03 Jun 2016 22:05:17 GMT
       
  • Application of Agree II Instrument for Appraisal of Postpartum Hemorrhage
           Clinical Practice Guidelines in Bosnia and Herzegovina

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Ahmed Novo, Andreja Subotic-popovic, Savka Strbac, Alma Kandic, and Mihai Horga.
      Introduction: Federal Minister of Health and Minister of Health and Social Welfare of the Republika Srpska as a Governmental health authorities in Federation of Bosnia and Herzegovina (FBiH) and the Republika Srpska nominated/appointed health professionals as their representatives to a multidisciplinary Guidelines Adaptation Group (GAG). This group started with its work in September 2015. The main purpose of the guidelines development exercise is to develop guidelines with worldwide recognized methodology for clinical guidelines development and adaptation. At the end of this consultancy, GAG would have develop a clinical practice guideline on Postpartum hemorrhage (PPH) through the adaptation method, starting from published international clinical guidelines and adapting it according to the country specific requirements. Methodology: During the process of identifying the best guideline for adaptation, the GAG had to pass several steps. One of the crucial steps was to identify the questions related to clinical practice and health policy for which answers are needed to be addressed by the guideline. These questions included relevant issues regarding the topic area such as diagnosis, prognosis, intervention, service delivery, and training. After that, six guidelines have been researched by the six members of the GAG to see if they answered the identified questions. Evaluating the methodological quality of the selected clinical guidelines was a second essential step before deciding which ones could best fit the needs and interests. AGREE II instrument has been chosen as methods for evaluating clinical guideline quality and appropriateness. Four appraisers conducted the assessment of each of the selected guidelines for PPH. All appraisers passed the training for the AGREE II instrument before conducting appraisals, as recommended by the AGREE collaboration. Each of the four guidelines was rated independently with the AGREE II tool by each appraiser. Results: The highest score was obtained by the WHO recommendations for postpartum hemorrhage guidelines and each of four assessors recommended it to be adapted and further implemented. Discussion: In spite of several serous attempts and two Agencies for quality improvement in BiH the whole process of guideline adaptation is still in the beginning and therefore the establishment of a strong connection with similar institutions and organizations from our region and the rest of the world is very important. Cooperation and collaboration across institutions and countries and key stakeholders have potential to significantly improve the validity and quality of the adapted guidelines and to positively influence implementation.

      PubDate: Fri, 03 Jun 2016 22:04:13 GMT
       
  • Recommendations for Using Barcode in Hospital Process

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Peyman Rezaei Hachesu, Leila Zyaei‚ and Hadi Hassankhani.
      Background: Lack of attention to the proper barcode using leads to lack of use or misuse in the hospitals. The present research aimed to investigate the requirements and barrier for using barcode technology and presenting suggestions to use it. Methods: The research is observational-descriptive. The data was collected using the designed checklist which its validity was assessed. This check list consists of two parts: “Requirements” and “barrier” of using the barcodes. Research community included 10 teaching hospitals and a class of 65 participants included people in the hospitals. The collected data was analyzed using descriptive statistics. Results: Required changes of workflow processes in the hospital and compliance them with the hospital policy are such requirements that had been infringed in the 90 % of hospitals. Prioritization of some hospital processes for barcoding, system integration with Hospital Information system (HIS), training of staff and budgeting are requirements for the successful implementation which had been infringed in the 80% of hospitals. Dissatisfaction with the quality of barcode labels and lacks of adequate scanners both whit the rate of 100 %, and the lack of understanding of the necessary requirements for implementation of barcodes as 80% were the most important barrier. Conclusion: Integrate bar code system with clinical workflow should be considered. Lack of knowledge and understanding toward the infrastructure, inadequate staff training and technological problems are considered as the greatest barriers.

      PubDate: Fri, 03 Jun 2016 22:03:02 GMT
       
  • Documentation of Medical Records in Hospitals of Mazandaran University of
           Medical Sciences in 2014: a Quantitative Study

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Benyamin Mohseni Saravi, Zolaykha Asgari, Hasan Siamian, Ebrahim Bagherian Farahabadi, Alimorad Heidari Gorji, Nima Motamed, Mohammad Fallahkharyeki, Ramin Mohammadi.
      Introduction: Documentation of patient care in medical record formats is always emphasized. These documents are used as a means to go on treating the patients, staff in their own defense, assessment, care, any legal proceedings and medical science education. Therefore, in this study, each of the data elements available in patients’ records are important and filling them indicates the importance put by the documenting teams, so it has been dealt with the documentation the patient records in the hospitals of Mazandaran province. Method: This cross-sectional study aimed to review medical records in 16 hospitals of Mazandaran University of Medical Sciences (MazUMS). In order to collection data, a check list was prepared based on the data elements including four forms of the admission, summary, patients’ medical history and progress note. The data recording was defined as “Yes” with the value of 1, lack of recording was defined as “No” with the value of 2, and “Not applied” with the value of 0 for the cases in which the mentioned variable medical records are not applied. Results: The overall evaluation of the documentation was considered as 95-100% equal to “good”, 75-94% equal to “average” and below -75% equal to “poor”. Using the stratified random sample volume formula, 381 cases were reviewed. The data were analyzed by the SPSS version 19 and descriptive statistics. Results: The results showed that %62 of registration and all the four forms were in the “poor” category. There was no big difference in average registration among the hospitals. Among the educational groups Gynecology and Infectious were equal and had the highest average of documentation of %68. In the data categories, the highest documentation average belonged to the verification, %91. Conclusion: According to the overall assessment in which the rate of documentation was in the category “week”, we should make much more efforts to reach better conditions. Even if a data element is recognized meaningless, unnecessary and repetitive by the in charge of documentation, it should not be neglected and skipped. In order to solve the problems of these types, it is suggested to discuss the medical records forms and elements that seem unnecessary in the related committees.

      PubDate: Fri, 03 Jun 2016 22:01:51 GMT
       
  • Investigation of the Impact of Extracting and Exchanging Health
           Information by Using Internet and Social Networks

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      John Pistolis, Stelios Zimeras, Kostas Chardalias, Zoe Roupa, George Fildisis, and Marianna Diomidous.
      Introduction: Social networks (1) have been embedded in our daily life for a long time. They constitute a powerful tool used nowadays for both searching and exchanging information on different issues by using Internet searching engines (Google, Bing, etc.) and Social Networks (Facebook, Twitter etc.). In this paper, are presented the results of a research based on the frequency and the type of the usage of the Internet and the Social Networks by the general public and the health professionals. Objectives: The objectives of the research were focused on the investigation of the frequency of seeking and meticulously searching for health information in the social media by both individuals and health practitioners. The exchanging of information is a procedure that involves the issues of reliability and quality of information. Methods: In this research, by using advanced statistical techniques an effort is made to investigate the participant’s profile in using social networks for searching and exchanging information on health issues. Results: Based on the answers 93 % of the people, use the Internet to find information on health-subjects. Considering principal component analysis, the most important health subjects were nutrition (0.719 %), respiratory issues (0.79 %), cardiological issues (0.777%), psychological issues (0.667%) and total (73.8%). Conclusions: The research results, based on different statistical techniques revealed that the 61.2% of the males and 56.4% of the females intended to use the social networks for searching medical information. Based on the principal components analysis, the most important sources that the participants mentioned, were the use of the Internet and social networks for exchanging information on health issues. These sources proved to be of paramount importance to the participants of the study. The same holds for nursing, medical and administrative staff in hospitals.

      PubDate: Fri, 03 Jun 2016 22:00:42 GMT
       
  • Mobile Phone Based System Opportunities to Home-based Managing of
           Chemotherapy Side Effects

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Somayeh Davoodi, Zeinab Mohammadzadeh, and Reza Safdari.
      Objective: Applying mobile base systems in cancer care especially in chemotherapy management have remarkable growing in recent decades. Because chemotherapy side effects have significant influences on patient’s lives, therefore it is necessary to take ways to control them. This research has studied some experiences of using mobile phone based systems to home-based monitor of chemotherapy side effects in cancer. Methods: In this literature review study, search was conducted with keywords like cancer, chemotherapy, mobile phone, information technology, side effects and self managing, in Science Direct, Google Scholar and Pub Med databases since 2005. Results: Today, because of the growing trend of the cancer, we need methods and innovations such as information technology to manage and control it. Mobile phone based systems are the solutions that help to provide quick access to monitor chemotherapy side effects for cancer patients at home. Investigated studies demonstrate that using of mobile phones in chemotherapy management have positive results and led to patients and clinicians satisfactions. Conclusion: This study shows that the mobile phone system for home-based monitoring chemotherapy side effects works well. In result, knowledge of cancer self-management and the rate of patient’s effective participation in care process improved.

      PubDate: Fri, 03 Jun 2016 21:59:31 GMT
       
  • Conceptual Framework for Developing a Diabetes Information Network

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Hossein Riazi, Mostafa Langarizadeh, Bagher Larijani, and Leila Shahmoradi.
      Objective: To provide a conceptual framework for managing diabetic patient care, and creating an information network for clinical research. Background: A wide range of information technology (IT) based interventions such as distance learning, diabetes registries, personal or electronic health record systems, clinical information systems, and clinical decision support systems have so far been used in supporting diabetic care. Previous studies demonstrated that IT could improve diabetes care at its different aspects. There is however no comprehensive conceptual framework that defines how different IT applications can support diverse aspects of this care. Therefore, a conceptual framework that combines different IT solutions into a wide information network for improving care processes and for research purposes is widely lacking. In this study we describe the theoretical underpin of a big project aiming at building a wide diabetic information network namely DIANET. Research design and methods: A literature review and a survey of national programs and existing regulations for diabetes management was conducted in order to define different aspects of diabetic care that should be supported by IT solutions. Both qualitative and quantitative research methods were used in this study. In addition to the results of a previous systematic literature review, two brainstorming and three expert panel sessions were conducted to identify requirements of a comprehensive information technology solution. Based on these inputs, the requirements for creating a diabetes information network were identified and used to create a questionnaire based on 9-point Likert scale. The questionnaire was finalized after removing some items based on calculated content validity ratio and content validity index coefficients. Cronbach’s alpha reliability coefficient was also calculated (αTotal= 0.98, P

      PubDate: Fri, 03 Jun 2016 21:58:05 GMT
       
  • Semantic-Web Architecture for Electronic Discharge Summary Based on OWL
           2.0 Standard

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Shahram Tahmasebian, Mostafa Langarizadeh, Marjan Ghazisaeidi, and Reza Safdari.
      Introduction: Patients’ electronic medical record contains all information related to treatment processes during hospitalization. One of the most important documents in this record is the record summary. In this document, summary of the whole treatment process is presented which is used for subsequent treatments and other issues pertaining to the treatment. Using suitable architecture for this document, apart from the aforementioned points we can use it in other fields such as data mining or decision making based on the cases. Material and Methods: In this study, at first, a model for patient’s medical record summary has been suggested using semantic web-based architecture. Then, based on service-oriented architecture and using Java programming language, a software solution was designed and run in a way to generate medical record summary with this structure and at the end, new uses of this structure was explained. Results: in this study a structure for medical record summaries along with corrective points within semantic web has been offered and a software running within Java along with special ontologies are provided. Discussion and Conclusion: After discussing the project with the experts of medical/health data management and medical informatics as well as clinical experts, it became clear that suggested design for medical record summary apart from covering many issues currently faced in the medical records has also many advantages including its uses in research projects, decision making based on the cases etc.

      PubDate: Fri, 03 Jun 2016 21:56:57 GMT
       
  • One Year Follow-Up After Veriflex Phakic Intraocular Lenses Implantation
           for Correction of Myopia

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Melisa Ahmedbegovic Pjano, Alma Biscevic, Senad Grisevic, Ajla Pidro, Mirko Ratkovic, Maja Bohac, Amila Alikadic Husovic, Refet Gojak.
      Objectives: The aim of this study was to evaluate visual and refractive outcomes after Veriflex phakic intraocular lenses (pIOL) implantation in moderately myopic eyes as well as postoperative complications. Methods: This prospective clinical study included 40 eyes of 26 patients which underwent implantation of Veriflex for correction of myopia from -6.00 to -14.50 diopters (D) in the Eye Clinic Svjetlost Sarajevo, from January 2011 to January 2014. Uncorrected distance visual acuity (UDVA), manifest residual spherical equivalent (MRSE), intraocular pressure (IOP), endothelial cell (EC) density were evaluated at one, three, six and 12 months. Other complications in postoperative period were evaluated. For statistical analysis SPSS for Windows and Microsoft Excel were used. Results: Out of 26 patients 14 had binocular and 12 monocular procedure, with mean age of 29.8±6.5 years. After 12 months mean UDVA was 0.73±0.20. Mean MRSE was -0.39±0.31D and 90% of eyes had MRSE within ±1D. EC loss was 7.18±4.33%. There was no significant change of IOP by the end of 12 months follow up period. The only intraoperative complication was hyphema and occurred in one eye. Few postoperative complications were: subclinical inflammation in three eyes (7,5%), pigment dispersion in four eyes (10%), ovalisation of papilla in 2 eyes (5%) and decentration of pIOL in 2 eyes (5%). Conclusion: Implantation of iris-claw phakic lenses Veriflex for treating moderately high myopia is a procedure with good visual and refractive results and few postoperative complications.

      PubDate: Fri, 03 Jun 2016 21:55:08 GMT
       
  • Echocardiographic Assessment of Ischaemic Mitral Regurgitation, Mechanism,
           Severity, Impact on Treatment Strategy and Long Term Outcome

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Nabil Naser, Alen Dzubur, Zumreta Kusljugic, Katarina Kovacevic, Mehmed Kulic, Sekib Sokolovic, Ibrahim Terzic, Ilirijana Haxihibeqiri-Karabdic, Zorica Hondo, Snjezana Brdzanovic, and Sanja Miseljic.
      Introduction: The commonest mitral regurgitation etiologies are degenerative (60%), rheumatic post-inflammatory, 12%) and functional (25%). Due to the large number of patients with acute MI, the incidence of ischaemic MR is also high. Ischaemic mitral regurgitation is a complex multifactorial disease that involves left ventricular geometry, the mitral annulus, and the valvular/subvalvular apparatus. Ischaemic mitral regurgitation is an important consequence of LV remodeling after myocardial infarction. Research Objectives: The objective of this study is to determine the role of echocardiography in detecting and assessment of mitral regurgitation mechanism, severity, impact on treatment strategy and long term outcome in patients with myocardial infarction during the follow up period of 5 years. Also one of objectives to determine if the absence or presence of ischaemic MR is associated with increased morbidity and mortality in patients with myocardial infarction. Patients and methods: The study covered 138 adult patients. All patients were subjected to echocardiography evaluation after acute myocardial infarction during the period of follow up for 5 years. The patients were examined on an ultrasound machine Philips iE 33 xMatrix, Philips HD 11 XE, and GE Vivid 7 equipped with all cardiologic probes for adults and multi-plan TEE probes. We evaluated mechanisms and severity of mitral regurgitation which includes the regurgitant volume (RV), effective regurgitant orifice area (EROA), the regurgitant fraction (RF), Jet/LA area, also we measured the of vena contracta width (VC width cm) for assessment of IMR severity, papillary muscles anatomy and displacement, LV systolic function ± dilation, LV regional wall motion abnormality WMA, LV WMI, Left ventricle LV remodeling, impact on treatment strategy and long term mortality. Results: We analyzed and follow up 138 patients with previous (>16 days) Q-wave myocardial infarction by ECG who underwent TTE and TEE echocardiography for detection and assessment of ischaemic mitral regurgitation (IMR) with baseline age (62 ± 9), ejection fraction (EF 41±12%), the regurgitant volume (RV) were 42±21 mL/beat, and effective regurgitant orifice area (EROA) 20±16 mm2, the regurgitant fraction (RF) were 48±10%, Jet/LA area 47±12%. Also we measured the of vena contracta width (VC width cm) 0,4±0,6 for assessment of IMR severity. During 5 years follow up, total mortality for patients with moderate/severe IMR–grade II-IV (54.2±1.8%) were higher than for those with mild IMR–grade I (30.4±2.9%) (P

      PubDate: Fri, 03 Jun 2016 21:53:44 GMT
       
  • A New Measurement Equivalence Technique Based on Latent Class Regression
           as Compared with Multiple Indicators Multiple Causes

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Jamshid Jamali, Seyyed Mohammad Taghi Ayatollahi, and Peyman Jafari.
      Background: Measurement equivalence is an essential prerequisite for making valid comparisons in mental health questionnaires across groups. In most methods used for assessing measurement equivalence, which is known as Differential Item Functioning (DIF), latent variables are assumed to be continuous. Objective: To compare a new method called Latent Class Regression (LCR) designed for discrete latent variable with the multiple indicators multiple cause (MIMIC) as a continuous latent variable technique to assess the measurement equivalence of the 12-item General Health Questionnaire (GHQ-12), which is a cross deferent subgroup of Iranian nurses. Methods: A cross-sectional survey was conducted in 2014 among 771 nurses working in the hospitals of Fars and Bushehr provinces of southern Iran. To identify the Minor Psychiatric Disorders (MPD), the nurses completed self-report GHQ-12 questionnaires and sociodemographic questions. Two uniform-DIF detection methods, LCR and MIMIC, were applied for comparability when the GHQ-12 score was assumed to be discrete and continuous, respectively. Results: The result of fitting LCR with 2 classes indicated that 27.4% of the nurses had MPD. Gender was identified as an influential factor of the level of MPD.LCR and MIMIC agree with detection of DIF and DIF-free items by gender, age, education and marital status in 83.3, 100.0, 91.7 and 83.3% cases, respectively. Conclusions: The results indicated that the GHQ-12 is to a great degree, an invariant measure for the assessment of MPD among nurses. High convergence between the two methods suggests using the LCR approach in cases of discrete latent variable, e.g. GHQ-12 and adequate sample size.

      PubDate: Fri, 03 Jun 2016 21:52:16 GMT
       
  • Imaging Characteristics and Prevalence of Pancreatic Carcinoma in Kosovo
           During 2011-2015 - Diagnostic Method as Choice

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Kreshnike Dedushi, Serbeze Kabashi, Sefedin Mucaj, Gazmed Hasbahta, Naser Ramadani, and Astrit Hoxhaj.
      Introduction: Pancreatic cancer is the 10th most common malignancy and the 4th largest cancer killer in adults. Aim: The purpose of this paper is to evaluate the number of cases presented with pancreatic carcinoma during the years 2011-2015, our experience of the imaging characteristics of pancreatic carcinoma. We evaluated prevalence of the pancreatic cancers, distant metastases and other local infiltration signs among the total cases of the pancreatic cancers diagnosed in the University Clinical Center of Kosovo, with the aim to compare these research findings to similar studies made in the developed countries. This is a retrospective research study done during the period of 2011-2015. Materials and Methodology: This retrospective research study includes 362 patients recently diagnosed with pancreatic cancer, examined in the period of 2011-2015 at the University Clinical Center of Kosovo. The imaging diagnostics are performed with MSCT Sensation 64 Siemens, MSCT Emotion 6 Siemens, and 1.5T MRI Symphony Siemens, biopsy guide with MSCT Sensation 64 Siemens in the Radiologic Clinic of UCCK; while the histopathology diagnostics has been performed in Clinic of Pathology at UCCK and prevalence is taken from the number of cases Reported at the Institute of Oncology Institute of Statistics and NIPH (National Institute of Public Health of Kosovo). Results: Out of a total of the 362 patients diagnosed with pancreas cancer, results is female 39.5% (n=143) and male 61.5% (n=219), report M: F (1: 1.6), 286 cases resulted in head and neck 79 % (n=286), 76 cases resulted in body and tail cancers (21%), distant metastases in first imaging modality were found in(n=155) patients 43 %, local infiltration was found in patients: gastric infiltration 15 % (n=54), duodenal and papilla infiltration 26% (n=94), local infiltration spleen 16% (n=57), local infiltration mesentery 43 % (n= 155), dilated biliary tree 34 % (n=123), regional lymph node infiltration 83 % (n= 300). Out of a total of the 362 patients diagnosed with pancreas cancer, 346 cases resulted> 2 cm and 16 cases resulted < 2 cm and with component cystic was 41.2 % ( n = 149), solid with component cystic – necrotic 33% (n= 119), solid 25.7% (n= 93). The prevalence is 19.9: 100,000 inhabitants. Conclusions: Prevalence of carcinoma of the pancreas for 5 years in Kosovo has proved to be prevalence is 19.9: 100,000 inhabitants. Seventy-four percent (74 %, n= 268) of all cancers are found in Stage III and IV. From an imaging point of view, these cancers were presented in an advanced stage, mainly due to their late clinical symptoms and limited access to imaging methods in our country.

      PubDate: Fri, 03 Jun 2016 21:50:55 GMT
       
  • Usefulness of Total PSA Value in Prostate Diseases Diagnosis

    • Abstract: 2016-06-08T23-15-24Z
      Source: Acta Informatica Medica
      Alden Prcic, Edin Begic, and Mustafa Hiros.
      Introduction: Analysis of total value of prostate specific antigen (PSAT), with the unavoidable digital rectal examination (DRE) is the basis of prostate cancer detection. Aim: The aim of this study was to determine the specificity and sensitivity of the total value of PSAT in the diagnosis of prostate cancer. The aim was also to determine the significance of PSAT in diagnosis of benign prostate hyperplasia, precancerous conditions and inflammatory and atrophic changes of the prostate. Material and methods: Data were collected from the “Register of PH biopsy” of Clinic of Urology, CCU Sarajevo. Results: Analysis of correlation between the diagnosis and the PSAT value shows statistically significant negative correlation (r =-0,186; p = 0.006) in the sense that the value of the PSAT is highest in cancer patients, and the lowest in patients with benign prostatic hyperplasia. PSAT increases with age (r = 0.152; p = 0.025). For prostate cancer optimal sensitivity and specificity for PSAT value occurs at cut off value of> 8.6 ng /mL. Values lower than 2 ng/mL and higher than 10 ng/mL are most specific, and PPV increases with increasing value of PSAT. PSAT at values of 10 ng/mL are at high levels of specificity, and value> 10 ng / mL is also of high sensitivity in the detection of prostate cancer, and in this moment these values represent the optimal mode for the subsequent treatment. Conclusion: PSAT has a relative significance in the detection of prostate cancer, and should not be used as a guideline without DRE.

      PubDate: Fri, 03 Jun 2016 21:49:28 GMT
       
  • Investigation of the Impact of Extracting and Exchanging Health
           Information by Using Internet and Social Networks

    • Abstract: 2016-04-06T20-37-13Z
      Source: Acta Informatica Medica
      John Pistolis, Stelios Zimeras, Kostas Chardalias, Zoe Roupa, George Fildisis, Marianna Diomidous.
      Introduction: Social networks (1) are embedded in our daily life a long time ago. They constitute a powerful tool (1, 2) used nowadays for both searching and exchanging information on different issues by using internet searching engines (Google, Facebook, e.t.c.). In this paper, a research is presented based on the issue of the usage of internet & social networks by the general public and the health professionals. Objectives: The objective was to investigate the frequency of seeking and meticulously searching for health information in the social media by both individuals and health practitioners. The exchanging of information is a procedure that involves the issues of reliability and quality of information (1). Methods: In this work, by using advanced statistical techniques an effort is made to investigate the participant’s profile in using social networks for digging and exchanging information on health issues. Results: Based on the answers 93 % of the people are using the internet for finding information on health-subjects. Considering principal component analysis, the most important subjects were nutrition (0.719 %), respiratory issues (0.79 %), cardiological issues (0.777%), psychological issues (0.667%) and total (73.8 %). Conclusions: On the final conclusion, based on different statistical techniques, the findings were that the 61.2% of the males and 56.4% of the females indented to use the social networks for searching medical information. Based on the principal components analysis, the most important human-sources that people mentioned, those on the use of internet and social networks for exchanging information on health issues is of paramount importance. The same holds for nursing, medical and administrative staff in hospitals.

      PubDate: Sat, 02 Apr 2016 11:27:21 GMT
       
  • The Most Influential Scientist in the Development of Medical informatics
           (11): David B. Shires

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Sat, 26 Mar 2016 08:55:50 GMT
       
  • MRI Verification of a Case of Huge Infantile Rhabdomyoma

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Naser Ramadani, Kreshnike Dedushi Kreshnike, Sefedin Muçaj, Serbeze Kabashi, Astrit Hoxhaj, Naim Jerliu, Ramush Bejiçi.
      Introduction: Cardiac rhabdomyoma is type of benign myocardial tumor that is the most common fetal cardiac tumor. Cardiac rhabdomyomas are usually detected before birth or during the first year of life. They account for over 60% of all primary cardiac tumors. Case report: A 6 month old child with coughing and obstruction in breathing, was hospitalized in the Pediatric Clinic in UCCK, Pristine. The difficulty of breathing was heard and the pathological noise of the heart was noticed from the pediatrician. In the echo of the heart at the posterior and apico-lateral part of the left ventricle a tumoral mass was presented with the dimensions of 56 x 54 mm that forwarded the contractions of the left ventricle, the mass involved also the left ventricle wall and was not vascularized. The right ventricle was deformed and with the shifting of the SIV on the right the contractility was preserved. Aorta, the left arch and AP were normal with laminar circulation. The pericard was presented free. Radiography of thoracic organs was made; it resulted on cardiomegaly and significant bronchovascular drawing. It was completed with an MRI and it resulted on: Cardiomegaly due to large tumoral mass lesion (60x34 mm) involving lateral wall of left ventricle. It was isointense to the muscle on T1W images, markedly hyperintense on T2W images. There were a few septa or bant like hypointensities within lesion. On postcontrast study it showed avid enhancement. The left ventricle volume was decreased. Mild pericardial effusion was also noted. Surgical intervention was performed and it resulted on the histopathological aspect as a huge infantile rhadbomyoma. Conclusion: In most cases no treatment is required and these lesions regress spontaneously. Patients with left ventricular outflow tract obstruction or refractory arrhythmias respond well to surgical excision. Rhabdomyomas are frequently diagnosed by means of fetal echocardiography during the prenatal period.

      PubDate: Sat, 26 Mar 2016 08:55:10 GMT
       
  • Hashimoto Thyroiditis and Nephrocalcinosis in a Child with Down Syndrome

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Lidvana Spahiu, Haki Jashari, Vjosa Mulliqi-Kotori, Blerta Elezi-Rugova, Besart Merovci.
      Introduction: Hypothyroidism has been reported to affect renal function and structure. However, the association of hypothyroidism with distal renal tubular acidosis (dRTA) is rarely reported in children. Case Presentation: We present a 6-year-boy with Down syndrome admitted in our department due to vomiting, weakness, polyuria, polydipsia, irritability and weight loss in the last few weeks. Investigations revealed features of hypokalemia, metabolic acidosis and alkaline urine consistent with dTRA. Abdominal ultrasound found nephrocalcinosis. In addition, Antithyroid peroxidase antibodies were positive, suggesting an autoimmune background for the pathogenesis of the tubular dysfunction. Treatment for dRTA and hypothyroidism was started and symptomatic improve was noticed. Conclusion: dRTA should be excluded in children with autoimmune disorders who develop weakness, polyuria, polydipsia or growth failure. Early diagnosis would reduce long-term complications.

      PubDate: Sat, 26 Mar 2016 08:52:39 GMT
       
  • Bariatric Surgery in University Clinic Center Tuzla - Results After 30
           Operations

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Amir Ahmetasevic, Fuad Pasic, Miroslav Bekavac Beslin, Miroslav Ilic, Dzenita Ahmetasevic, Mirza Mesic.
      Introduction: Project of Bariatric surgery in University clinic center (UCC) Tuzla has been initiated in 2009 as an idea of professor Dešo Mešić and soon after that Bariatric surgical team led by doctor Fuad Pasic has been created. Material and methods: Practical team education was realized in Croatia in hospital „Sisters of Mercy“ under supervision of professor Miroslav-Bekavac Beslin. First bariatric operations in UCC Tuzla has been done in 2011 and it was biliopancreatic diversion (BPD) Scopinaro. Results and discussion: So far there has been done 30 operations and among them there have been used almost all operative modalities - restrictive, malabsorptive and combined (laparoscopic gastric banding-LAPGB, Roux-y mini gastric bypass,open and laparoscopic gastric sleeve resection, and over mentioned Scopinaro’s BPD). Beginning results are very promising according to the fact that almost all operated patients after one year stopped using antihypertensive, antidiabetic and antidepressant therapy, that average year’s weight loss is 35-100 kilograms and total satisfactions of patients after surgeries is obvious.

      PubDate: Sat, 26 Mar 2016 08:51:01 GMT
       
  • Social Network Sites as Educational Factors

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Alireza Ebrahimpour, Farnaz Rajabali, Fatemeh Yazdanfar, Reza Azarbad, Majid Rezaei Nodeh, Hasan Siamian, Mohammad Vahedi.
      Background: in this present era, the technology development has established certain type of communication. Nowadays education as the fundamental principle in transferring cognition to the learners has found various methods. Recently the concept that social networks could be effective tool in easing the achievement to the educational goals has been under attention. Therefore, this investigation is trying to find out whether, the social networks could play role on the process of education among students' Materials and Methods: This cross sectional descriptive study was performed on 1000 students from 7 medical universities in 2015. The data collection tool was questionnaire that was approved Cronbach’s alpha was 0.85. Meanwhile its validity was confirmed too. The obtained data were analyzed by the descriptive statistic, ANOVA, Turkey and used X2 SPSS-19. Results: In this investigation, 940 subjects were under study. 85% used daily the social network. The highest usage was attributed to the Telegram. 52% preferred image suitable for transferring of information. Even though, 73% believed that these networks have significant effects on coordinating of students with in university charges. Conclusion: Considering the findings of the present study, it is proposed that the universities integrate the social networks in the education programs and recognize it as the awareness factor, therefore benefit it in the educational affairs.

      PubDate: Sat, 26 Mar 2016 08:41:31 GMT
       
  • Quality of Public Hospitals Websites: A Cross-Sectional Analytical Study
           in Iran

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Salarvand Shahin, Samadbeik Mahnaz, Tarahi Mohammad Javad, Salarvand Hamed.
      Introduction: Nowadays, hospitals have turned increasingly towards the Internet and develop their own web presence. Hospital Websites could be operating as effective web resources of information and interactive communication mediums to enhance hospital services to the public. Aim: Therefore, the aim of this study was to assess the quality of websites in Tehran’s public hospitals. Material and methods: This cross-sectional analysis involved all public hospitals in Iran’s capital city, Tehran, with a working website or subsites between April and June, 2014 (N=59). The websites were evaluated using three validated instruments: a localized checklist, Google page rank, and the Alexa traffic ranking. The mentioned checklist consisted of 112 items divided into five sections: technical characteristics, hospital information and facilities, medical services, interactive on-line services and external activities. Data were analyzed using descriptive and analytical statistics. Results: The mean website evaluation score was 45.7 out of 224 for selected public hospitals. All the studied websites were in the weak category based on the earned quality scores. There was no statistically significant association between the website evaluation score with Google page rank (P=0.092), Alexa global traffic rank and Alexa traffic rank in Iran (P>0.05). The hospital websites had a lower quality score in the interactive online services and external activities criteria in comparing to other criteria. Due to the low quality level of the studied websites and the importance of hospital portals in providing information and services on the Internet, the authorities should do precise planning for the appreciable improvement in the quality of hospital websites.

      PubDate: Sat, 26 Mar 2016 08:40:12 GMT
       
  • Accreditation of Management Communication and Information Systems in
           Public Hospitals of Sabzevar City, Iran

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Fereshteh Farzianpour, Saeed Shojaei, Mohammad Arab, Abbas Rahimi Foroushani.
      Objective: Information systems are “computer systems that collect, store, process, retrieve, show, and provide timely information required in practice, education, management, and research”. The purpose of these systems is to support hospital activities in practical, tactical, and strategic levels in order to provide better service to patients. This study aimed to evaluate the communication and information system (MCI) in public hospitals in Sabzevar city in 2014 from the perspective of human resources according to international standards of the Joint Commission Accreditation Hospital (JCAH). Methods: This study was a practical, descriptive, cross-sectional study. The study population consisted of Sabzevar nurses who used hospital information system. Sampling was done by classification method and in proportion to the number of nurses in each health care units in hospitals in 2014. The sample size was 200 and after referring to hospitals, 200 questionnaires were completed. Sample size was calculated by the formula n=Z2P (1-P)/d2 with P=0.5, α=0.05, d=0.05, and Z=1.96. Data collection tool was the questionnaire of assessment of hospital information systems of JCAH, which has 124 specific questions, including 6 areas. To assess the effect of demographic variables with MCI standards of two questionnaires (feasibility and implementation), the following steps were taken. 1. Kolmogorov-Smirnov test was used to determine whether responses were normal or not. 2. In case of normal data, t-test was used for dual groups and one-way ANOVA test for groups of three or more. 3. If not normal, Mann-Whitney test was used for dual groups and Kruskal-Wallis test for groups of three or more. Results: Research findings show the mean results of feasibility and implementation of all 6 areas of international standards MCI have feasibility in three hospitals in Sabzevar in 20 sections (H1=105.01±10.468), (H1=196.31±4.662), (H2=104.26±9.099), (H2=195.33±3.778) (H3=106.48±11.545) and (H3=197.57±4.943), respectively. Conclusion: The results showed that the mean feasibility and implementation of all six areas of MCI international standards is practical in three hospitals in Sabzevar in 20 wards. Also, 50% of users in clinical departments, physicians, and nurses agreed to appropriateness of the hospital information and communication systems for doing their duties.

      PubDate: Sat, 26 Mar 2016 08:37:54 GMT
       
  • Conceptual Model of Clinical Governance Information System for Statistical
           Indicators by Using UML in Two Sample Hospitals

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Fatemeh Rangraz Jeddi, Mehrdad Farzandipoor, Masoud Arabfard, and Azam Haj Mohammad Hosseini.
      Objective: The purpose of this study was investigating situation and presenting a conceptual model for clinical governance information system by using UML in two sample hospitals. Background: However, use of information is one of the fundamental components of clinical governance; but unfortunately, it does not pay much attention to information management. Material and Methods: A cross sectional study was conducted in October 2012- May 2013. Data were gathered through questionnaires and interviews in two sample hospitals. Face and content validity of the questionnaire has been confirmed by experts. Data were collected from a pilot hospital and reforms were carried out and Final questionnaire was prepared. Data were analyzed by descriptive statistics and SPSS 16 software. Results: With the scenario derived from questionnaires, UML diagrams are presented by using Rational Rose 7 software. The results showed that 32.14 percent Indicators of the hospitals were calculated. Database was not designed and 100 percent of the hospital’s clinical governance was required to create a database. Conclusion: Clinical governance unit of hospitals to perform its mission, do not have access to all the needed indicators. Defining of Processes and drawing of models and creating of database are essential for designing of information systems.

      PubDate: Sat, 26 Mar 2016 08:36:39 GMT
       
  • Determination of Minimum Data Set (MSD) in Echocardiography Reporting
           

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Zahra Mahmoudvand, Mehran Kamkar, Leila Shahmoradi, Ahmadreza Farzaneh Nejad.
      Background: Determination of minimum data set (MDS) in echocardiography reports is necessary for documentation and putting information in a standard way, and leads to the enhancement of electrocardiographic studies through having access to precise and perfect reports and also to the development of a standard database for electrocardiographic reports. Aim: to determine the minimum data set of echocardiography reporting system to exchange with Iran’s electronic health record (EHR) system. Methods: First, a list of minimum data set was prepared after reviewing texts and studying cardiac patients’ records. Then, to determine the content validity of the prepared MDS, the expert views of 10 cardiologists and 10 health information management (HIM) specialists were obtained; to estimate the reliability of the set, test-retest method was employed. Finally, the data were analyzed using SPSS software. Results: The highest degree of consensus was found for the following MDSs: patient’s name and family name (5), accepting doctor’s name and family name, familial death records due to cardiac disorders, the image identification code, mitral valve, aortic valve, tricuspid valve, pulmonary valve, left ventricle, hole, atrium valve, Doppler examination of ventricular and atrial movement models and diagnoses with an average of. Conclusions: To prepare a model of echocardiography reporting system to exchange with EHR system, creation a standard data set is the vital point. Therefore, based on the research findings, the minimum reporting system data to exchange with Iran’s electronic health record system include information on entity, management, medical record, carried-out acts, and the main content of the echocardiography report, which the planners of reporting system should consider.

      PubDate: Sat, 26 Mar 2016 08:35:12 GMT
       
  • Design and Development of a Clinical Risk Management Tool Using Radio
           Frequency Identification (RFID)

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Faramarz Pourasghar, Jafar Sadegh Tabrizi, Khadijeh Yarifard.
      Background: Patient safety is one of the most important elements of quality of healthcare. It means preventing any harm to the patients during medical care process. Objective: This paper introduces a cost-effective tool in which the Radio Frequency Identification (RFID) technology is used to identify medical errors in hospital. Methods: The proposed clinical error management system (CEMS) is consisted of a reader device, a transfer/receiver device, a database and managing software. The reader device works using radio waves and is wireless. The reader sends and receives data to/from the database via the transfer/receiver device which is connected to the computer via USB port. The database contains data about patients’ medication orders. Results: The CEMS has the ability to identify the clinical errors before they occur and then warns the care-giver with voice and visual messages to prevent the error. This device reduces the errors and thus improves the patient safety. Conclusion: A new tool including software and hardware was developed in this study. Application of this tool in clinical settings can help the nurses prevent medical errors. It can also be a useful tool for clinical risk management. Using this device can improve the patient safety to a considerable extent and thus improve the quality of healthcare.

      PubDate: Sat, 26 Mar 2016 08:33:03 GMT
       
  • The Diagnostic Value of MRI in Brucella Spondylitis With Comparison to
           Clinical and Laboratory Findings

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Ali Baradaran Bagheri, Koorosh Ahmadi, Niaz Mohamad Jafari Chokan, Bita Abbasi, Reza Akhavan, Ehsan Bolvardi, Somayeh Soroureddin.
      Background: Brucellosis is an endemic zoonotic disease, especially in the Middle East and Mediterranean regions and can involve many organs and tissue. Osteoarticular involvement is the most common complication. Spondylitis is its most prevalent clinical form in adults, and there may be difficult in diagnosis and treatment. In present study, we aimed to assess these diagnostic value of MRI, in patients with spondylitis due to brucella, comparing with clinical and laboratory findings. Method: Patients with low back pain who were admitted to Sheikhol-raees MRI center were included in this study. None of these patients had any documented infectious disease. Diagnosis of brucellosis was made, based on MRI findings, which would be approved by serology. After confirmation with serology, the group with positive serology were compared with the negative group, in sex, age, MRI findings level of vertebral involvements, signal intensity in T1 weighted and T2 weighted. Results: Among 53 patients with diagnosis of brucella spondylitis, 33 underwent serology study, 20 were positive and 13 were negative and the others consider out of study. From these 20, 3 had tuberculosis spondylitis, whose mean age was 56 and the 67% of them were male. Mean age in the positive brucella spondylitis were 46 and 67% of them were male. In negative group mean age was 55, and of whom 57% were male. There was no statistically significant difference in MRI findings such as changes in signal intensity, disk space narrowing, Intracanalicular mass, Abscess formation. Level of invlovment in vertebrae. Conclusion: The results of this study shows that although MRI is Modality of choice in diagnosis of spondylitis, it is not enough specific to diagnosis the reasons of spondylitis.

      PubDate: Sat, 26 Mar 2016 08:31:21 GMT
       
  • The Significance of MRI Evaluation of the Uterine Junctional Zone in the
           Early Diagnosis of Adenomyosis

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Amela Sofic, Azra Husic-Selimovic, Aladin Carovac, Elma Jahic, Velda Smailbegovic, Jana Kupusovic.
      Goal: The aim of the study is to define the MRI appearance of disorder in the Junctional zone (JZ) in women with adenomyosis compared to those without it, given the importance of the JZ in the regulation of various reproductive events. Materials and methods: This was a prospective, comparative and open study. Patients with adenomyosis have been sorted in target group, n = 82, while the control group consisted of patients without adenomyosis, n = 82. All patients, from both groups have undergone a magnetic resonance imaging of the pelvis. Using a software tool for measurement, the thickness of the JZ was measured in T2w sag sequences in all patients from both groups (target and control) n = 164. Patients in the target group type adenomyosis were assessed and categorized either as: diffuse, focal, or Adenomyoma and the results were compared. The presence of endometriosis and myomas in both groups was evaluated and its coexistence with adenomyosis was analyzed as well. Results: Of the 82 patients in the target group, 81.7% of the patients had diffuse adenomyosis, while 18.3% had focal type with statistically significant difference (p

      PubDate: Sat, 26 Mar 2016 08:29:48 GMT
       
  • Advantages of Combined PET-CT in Mediastinal Staging in Patients with
           Non-small Cell Lung Carcinoma

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Nermina Beslic, Amera Sadija, Renata Milardovic, Timur Ceric, Sejla Ceric, Adnan Beganovic, Spomenka Kristic, Semra Cavaljuga.
      Introduction: Precise mediastinal lymph node staging in patients with non-small cell lung carcinoma (NSCLC) provides important prognostic information and it is obligatory in treatment strategy planning. 18Fluoro-deoxy-glucose (18F-FDG) positron emission tomography - computerized tomography (PET-CT) based on detection of metabolic activity showed superiority in preoperative staging of lung carcinoma. Materials and Methods: Total number of 26 patients diagnosed with NSCLC were included in this retrospective, cross-sectional study. Status of mediastinal lymph nodes was assessed in all patients comparing contrast enhanced CT and 18F-FDG PET-CT findings. Discussion: We found in our study that 50% of patients had different N stage on contrast enhanced CT comparing to 18F-FDG PET-CT findings. Among the total number of patients which had different nodal status on PET-CT comparing to CT alone, we found in our study that 54% of patients had change in further therapy protocol after PET-CT change of nodal stage. Conclusion: Combined PET-CT which offers advantages of both modalities is excellent method for nodal (N) staging, so it is recommended in initial staging in patients with NSCLC. PET-CT used preopratively for mediastinal nodal staging has significant impact on further therapy planning and also has an consequential impact on health system savings.

      PubDate: Sat, 26 Mar 2016 08:27:42 GMT
       
  • Evaluation of Diagnostic Methods in the Differentiation of Heart Murmurs
           in Children

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Zijo Begic, Senad Pesto, Senka Mesihovic Dinarevic, Edin Begic, Amra Dobraca, Izet Masic.
      Introduction: The most common clinical sign in pediatric cardiology is a heart murmur (organic and inorganic). Organic are sign of heart disease, while inorganic (basically divided into accidental and functional) murmurs occur on anatomically healthy heart.. Aim: To determine the justification of the application of the methods of cardiac treatment. Patients and methods: Study included 116 children aged from 1 to 15 years, who were referred due to cardiac treatment to Pediatric Clinic, of Sarajevo University Clinical Center. Results: The first group consisted of children with innocent heart murmur, 97 (53 males). The second group consisted of patients with organic murmur, 19 (13 males). The average age of the first group was 7.69 (1.01–15.01) years old, and of the second group 3.15 (1.01- 8.06) years old, and there is a significant difference between these two groups (p

      PubDate: Sat, 26 Mar 2016 08:25:37 GMT
       
  • Use of Databases for Early Recognition of Risk of Diabetic Complication by
           Analysis of Liver Enzymes in Type 2 Diabetes Mellitus

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Maja Malenica, Besim Prnjavorac, Adlija Causevic, Tanja Dujic, Tamer Bego, Sabina Semiz.
      Introduction: Because of increasing prevalence of T2MD worldwide, it’s very important to recognize risk factors for diabetic complications, as soon as possible. Symptoms of complications appear a few or many years after tissue damage. So, it’s imperative to establish surveillance of diabetics with laboratory and other diagnostic procedures for early recognition of diabetic complications. Follow up of clinical curs of diabetes, by using databases of patients, provide possibility for permanent analysis of important laboratory parameters and any changes could be registered. Although an emerging evidence suggests a strong association of ALT (alanine aminotransferase) and γGT (gamma glutamyl transferase) activity with type 2 diabetes mellitus (T2DM), only a limited number of studies have analyzed the association of AST (aspartate aminotransferase), ALT, γGT, and ALP (alkaline phosphatase) activities in controlled T2DM. Material and Methods: Gender differences are of special interest in trying to follow diabetes progression and development of its complications. Here the activities of ALT, AST, γGT, ALP were analyzed as well as levels of glycosylated hemoglobin (HbA1c) and fasting plasma glucose (FPG) in 40 T2DM patients and 40 age-matched healthy subjects. Blood samples were collected from all participants in regular 3-months intervals up to 6 months period. Standard IFCC enzyme protocols were used to determine enzyme activities. Results and discussion: In first measured interval, significantly higher activities of ALT (p= 0,050) and glucose levels (p=0,045) were shown in male. A significant correlation was shown between ALT and AST activity with FPG and HbA1c levels in first and third measured interval. ALT activity was much higher in the group of patients with poor glycemia control. Average levels of activities of enzymes stay nearly in normal limits, but changes of enzymes activities should be recognized as soon as possible, earlier than tissue changes and diabetic complications become irreversible.

      PubDate: Sat, 26 Mar 2016 08:23:45 GMT
       
  • Review of the Journal Acta Informatica Medica During Eight Year Period:
           2008-2015

    • Abstract: 2016-03-28T04-23-16Z
      Source: Acta Informatica Medica
      Izet Masic, Edin Begic, Lejla Zunic.
      Introduction: Acta Informatica Medica is official journal of the Academy for Medical Sciences of Bosnia and Herzegovina (from 2014 Acta Inform Med is published bimonthly). Aim: To evaluate journal “Acta Informatica Medica” in 2015 and compare findings to previous years. Material and methods: The study has retrospective and descriptive character, and included the period 2008-2015 (included 36 issues of journal). Results: A total of 83 (average 13,8 articles per journal) articles were published in Acta Informatica Medica during 2015. Analyzing the type of articles, original articles are present in majority during 2015 (68,6%) (by analyzing last eight years, 310 (67,3%) were original). During 2015, 27,7% of articles were related to the applied of Health informatics in field of clinical medicine, 63,8% preclinical medicine and 8,5% to public health. Collaboration rate in 2015 was 0,84. Most often the time required for decision on acceptance of article in 2015 is between 50 and 60 days. Articles came from 16 countries. According to scimagojr.com for 2014, Acta Informatica Medica has SCImago Journal Rank 0,166, while Cites / Doc. (2years) parameter (widely used as impact index) is 0,70. According to GoogleScholar, h5 index is 11 and h5 median is 19. We analyzed the Acta Informatica Medica by “Publish or Perish” software - H index was 14, g index was 19 and e-index was 10.39. Conclusion: Year after year the highest number of original articles are published. Although the period of revision of articles is acceptable, the period up to two months is certainly not long, the goal is to reduce this period. Although the magazine in mentioned field found its place, although it is indexed in numerous bases, including: PubMed, PubMed Central, SCOPUS, EMBASE, EBSCO, etc. The main goal for next year is that the magazine becomes part of the Web of Science. Imperative is further internationalization of the magazine.

      PubDate: Sat, 26 Mar 2016 08:21:19 GMT
       
  • The Most Influential Scientist in the Development of Medical informatics
           (10): Marsden S. Blois

    • Abstract: 2016-02-10T04-32-18Z
      Source: Acta Informatica Medica
      Izet Masic.


      PubDate: Tue, 02 Feb 2016 05:45:28 GMT
       
 
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
 
Home (Search)
Subjects A-Z
Publishers A-Z
Customise
APIs
Your IP address: 54.81.190.231
 
About JournalTOCs
API
Help
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-2016