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Journal Cover   Acta Informatica Medica
  [SJR: 0.217]   [H-I: 4]   [0 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Print) 0353-8109 - ISSN (Online) 1986-5988
   Published by ScopeMed Homepage  [97 journals]
  • The Comparison of the Minimum Data Set for Elderly Health in Selected

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Nasrin Davaridolatabadi, Mehraban Shahi, Farahnaz Sadoughi, Maryam Ahmadi.
      Introduction: Ongoing increase in the elderly population in many developed countries has drawn attention to health of this age group. Recording adequate and relevant data for the elderly is considered as the basis for future planning for this segment of society. So this study was conducted to compare minimum data about elderly health in selected countries. Methods: This review study was conducted through Internet and library studies. Key words were extracted from search engines and data bases including Google, Yahoo, Google Scholar, PubMed, ProQuest and Iranian National Medical Digital Library. Inclusion criteria included English language with no time limits. All articles, research projects, theses, guidelines and progress reports were retrieved from the United States, Sweden, Japan and Iran and reviewed. Also, websites of organizations responsible for elderly health in selected countries were visited and their documents were reviewed. Results from this search were provided narratively and finally were presented within comparison tables. Findings: The findings of this study showed that elderly data in the selected countries are collected around four axis including minimum demographic data, medical histories, health assessment and financial data of elderly health. Discussion and Conclusion: Given the importance of the minimum data set of elderly health for future planning, the use of experiences of leading countries in elderly health seems necessary; however, localization of it according to the country’s needs is inevitable.

      PubDate: Sun, 22 Nov 2015 01:48:32 GMT
  • Discovering Diabetes Complications: an Ontology Based Model

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Tahani Daghistani, Riyad Al Shammari, Muhammad Imran Razzak.
      Background: Diabetes is a serious disease that spread in the world dramatically. The diabetes patient has an average of risk to experience complications. Take advantage of recorded information to build ontology as information technology solution will help to predict patients who have average of risk level with certain complication. It is helpful to search and present patient’s history regarding different risk factors. Discovering diabetes complications could be useful to prevent or delay the complications. Method: We designed ontology based model, using adult diabetes patients’ data, to discover the rules of diabetes with its complications in disease to disease relationship. Result: Various rules between different risk factors of diabetes Patients and certain complications generated. Furthermore, new complications (diseases) might be discovered as new finding of this study, discovering diabetes complications could be useful to prevent or delay the complications. Conclusion: The system can identify the patients who are suffering from certain risk factors such as high body mass index (obesity) and starting controlling and maintaining plan.

      PubDate: Sun, 22 Nov 2015 01:46:44 GMT
  • Research on the Submission, Acceptance and Publication Times of Articles
           Submitted to International Otorhinolaryngology Journals

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      M. Tayyar Kalcioglu, Yavuz Ileri, Servet Karaca, Oguz Kadir Egilmez, Numan Kokten.
      Objective: The aim of this study was to provide insight into the acceptance and publication times of articles submitted to international otolaryngology journals. Material and Methods: The study was carried out by examining the top 37 journal titles returned in an online search for otolaryngology journals published from 1999 to 2013 that have an international status based on their impact factor. Results: In total, 9,765 publications were examined. When journals were compared based on journal impact factor, statistically significant differences (p

      PubDate: Sun, 22 Nov 2015 01:43:58 GMT
  • Epilepsy Research in Iran: a Scientometric Analysis of Publications Output
           During 2000-2014

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Masoud Rasolabadi, Seyedeh Moloud Rasouli-Ghahfarkhi, Marlin Ardalan, Marya Maryam Kalhor, Jamal Seidi, Alireza Gharib.
      Aim: The aim of this study is to analyze the epilepsy research output of Iran in national and global contexts, as reflected in its publication output indexed in Scopus citation database during 2000-2014.Methods: This study was based on the publications of epilepsy research from Iranian authors retrieved Feb. 2015 from Scopus Citation database []. The string used to retrieve the data was developed using “epilepsy OR epilepsies” keywords in title, abstract and keywords and Iran in affiliation field was our main string. Results: Cumulative publication output of Iran in epilepsy research consisted of 702 papers from 2000 to 2014, with an average number of 46.53 papers per year. The total publication output of Iran in epilepsy research increased from 2 papers in 2000 to 88 papers in 2014. Hence, with 702 paper, Iran ranked 25th among the top 25 countries with a global share of 0.82 %. Iranian publication average citation per paper increased from 0 in 2000 to 7.88 in 2014. Overall, the received citations were 3184 citations during those years. Conclusion: Iran is collaborating with 36 countries with no more than 244 of its papers (35% of its total papers). It is necessary to prepare conditions for epilepsy researchers to collaborate more with international scientific societies in order to produce more and high quality papers.

      PubDate: Sun, 22 Nov 2015 01:42:16 GMT
  • The Evaluation of SEPAS National Project Based on Electronic Health Record
           System (EHRS) Coordinates in Iran

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Farkhondeh Asadi, Hamid Moghaddasi, Reza Rabiei, Forough Rahimi, Soheila Jahangiri Mirshekarlou.
      Background: Electronic Health Records (EHRs) are secure private lifetime records that can be shared by using interoperability standards between different organizations and units. These records are created by the productive system that is called EHR system. Implementing EHR systems has a number of advantages such as facilitating access to medical records, supporting patient care, and improving the quality of care and health care decisions. The project of electronic health record system in Iran, which is the goal of this study, is called SEPAS. With respect to the importance of EHR and EHR systems the researchers investigated the project from two perspectives: determining the coordinates of the project and how it evolved, and incorporating the coordinates of EHR system in this project. Methods: In this study two evaluation tools, a checklist and a questionnaire, were developed based on texts and reliable documentation. The questionnaire and the checklist were validated using content validity by receiving the experts’ comments and the questionnaire’s reliability was estimated through Test-retest(r =87%).Data were collected through study, observation, and interviews with experts and specialists of SEPAS project. Results: This research showed that SEPAS project, like any other project, could be evaluated. It has some aims; steps, operational phases and certain start and end time, but all the resources and required facilities for the project have not been considered. Therefore it could not satisfy its specified objective and the useful and unique changes which are the other characteristics of any project have not been achieved. In addition, the findings of EHR system coordinates can be determined in 4 categories as Standards and rules, Telecommunication-Communication facilities, Computer equipment and facilities and Stakeholders. Conclusions: The findings indicated that SEPAS has the ability to use all standards of medical terminology and health classification systems in the case of Maksa approval (The reference health coding of Iran).ISO13606 was used as the main standard in this project. Regarding the telecommunication-communication facilities of the project, the findings showed that its link is restricted to health care centers which does not cover other institutions and organizations involved in public health. The final result showed that SEPAS is in the early stages of execution. And the full implementation of EHR needs the provision of the infrastructure of the National Health Information Network that is the same as EHR system.

      PubDate: Sun, 22 Nov 2015 01:40:20 GMT
  • Computer Based Assessment of Cervical Vertebral Maturation Stages Using
           Digital Lateral Cephalograms

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Vildana Dzemidzic, Emir Sokic, Alisa Tiro, Enita Nakas.
      Objective: This study was aimed to investigate the reliability of a computer application for assessment of the stages of cervical vertebra maturation in order to determine the stage of skeletal maturity. Material and methods: For this study, digital lateral cephalograms of 99 subjects (52 females and 47 males) were examined. The following selection criteria were used during the sample composition: age between 9 and 16 years, absence of anomalies of the vertebrae, good general health, no history of trauma at the cervical region. Subjects with lateral cephalograms of low quality were excluded from the study.For the purpose of this study a computer application Cephalometar HF V1 was developed. This application was used to mark the contours of the second, third and fourth cervical vertebrae on the digital lateral cephalograms, which enabled a computer to determine the stage of cervical vertebral maturation. The assessment of the stages of cervical vertebral maturation was carried out by an experienced orthodontist. The assessment was conducted according to the principles of the method proposed by authors Hassel and Farman. The degree of the agreement between the computer application and the researcher was analyzed using by statistical Cohen Kappa test. Results: The results of this study showed the agreement between the computer assessment and the researcher assessment of the cervical vertebral maturation stages, where the value of the Cohen Kappa coefficient was 0.985. Conclusion: The computer application Cephalometar HF V1 proved to be a reliable method for assessing the stages of cervical vertebral maturation. This program could help the orthodontists to identify the stage of cervical vertebral maturation when planning the orthodontic treatment for the patients with skeletal disharmonies.

      PubDate: Sun, 22 Nov 2015 01:38:52 GMT
  • Gender Differences in Biochemical and Electroneurographic Parameters of
           Median and Ulnar Nerve

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Merita Tiric-Campara, Emir Tupkovic, Miro Denislic, Mirza Biscevic, Amira Skopljak, Jasminka Djelilovic-Vranic, Azra Alajbegovic.
      Introduction: In this article are demonstrated differences in the aspects of the metabolic syndrome (MSy) between genders, as well as the association of MSy and neuropathy. The aim: The aim of our study was that in patients with newly discovered metabolic syndrome of both sexes make comparison of fasting blood glucose levels and after oral glucose tolerance test, as well as neurophysiological parameters of n.medianus and n.ulnaris. Patients and methods: All participants were examined dermatologically. The analysis included the 36 male and 36 female respondents with a newly discovered MSy. Results: The average age of men was 52.75±7.5 (40-65) years and women 52.1±7.7 (38-67) years. The average value of fasting blood glucose in women was 5.86±0.87 (4.5-8) mmol/L, and non significantly higher in men (p=0.0969) as 6.19±0.8 (4.7-8) mmol/L. Average values of blood sugar 120 minutes after oral glucose tolerance test were not significantly different (p=0.7052), and was 5.41±1.63 (3.3-9.7) mmol/L in women and 5.27±1.52 (2.7-9.8) mmol/L in men. Median motor velocity were significantly higher in women for n.medianus on the left (p=0.0024), n.ulnaris on the left (p=0.0081) and n.ulnaris on the right side (p=0.0293), and the median motor terminal latency were significantly longer in n.ulnaris on the left (p=0.0349) and n.ulnaris on the right side (p=0.011). There was no significant difference in the sensory conductivity velocity in n.medianus and n.ulnaris between the groups, but the amplitude with the highest peak of the sensory response was significantly higher in n.medianus on the left (p=0.0269) and n.ulnaris on the left side (p=0.0009) in female patients. Conclusion: The results indicate that there are differences in neurophysiological parameters of the investigated nerves between the genders, and that tested nerve structures in the course of MSy are affected slightly more in men. There were no significant differences in skin changes between genders.

      PubDate: Sun, 22 Nov 2015 01:37:01 GMT
  • The Usage of Association Rule Mining to Identify Influencing Factors on
           Deafness After Birth

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Azimeh Danesh Shahraki, Reza Safdari, Hamid Habibi Gahfarokhi, Shahram Tahmasebian.
      Background: Providing complete and high quality health care services has very important role to enable people to understand the factors related to personal and social health and to make decision regarding choice of suitable healthy behaviors in order to achieve healthy life. For this reason, demographic and clinical data of person are collecting, this huge volume of data can be known as a valuable resource for analyzing, exploring and discovering valuable information and communication. This study using forum rules techniques in the data mining has tried to identify the affecting factors on hearing loss after birth in Iran. Materials and Methods: The survey is kind of data oriented study. The population of the study is contained questionnaires in several provinces of the country. First, all data of questionnaire was implemented in the form of information table in Software SQL Server and followed by Data Entry using written software of C # .Net, then algorithm Association in SQL Server Data Tools software and Clementine software was implemented to determine the rules and hidden patterns in the gathered data. Findings: Two factors of number of deaf brothers and the degree of consanguinity of the parents have a significant impact on severity of deafness of individuals. Also, when the severity of hearing loss is greater than or equal to moderately severe hearing loss, people use hearing aids and Men are also less interested in the use of hearing aids. Conclusion: In fact, it can be said that in families with consanguineous marriage of parents that are from first degree (girl/boy cousins) and 2nd degree relatives (girl/boy cousins) and especially from first degree, the number of people with severe hearing loss or deafness are more and in the use of hearing aids, gender of the patient is more important than the severity of the hearing loss.

      PubDate: Sun, 22 Nov 2015 01:35:21 GMT
  • Pachymetric Changes of the Cornea Amongst Patients Treated with LASIK

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Afrim Shabani, Minir Asani, Gazmend Kaçaniku, Valbon Ajazaj, Ermal Dida, Pajtim Lutaj.
      Purpose: In this study, we have researched the possible parametrically changes before and after LASIK (laser-assisted in situ keratomileusis) and the influence of these changes in the cause of post LASIK ectasia. Materials and methods: In this study 204 eyes with different refractive anomalies were included. Candidates that underwent refractive surgery first have to undergo many ophthalmological examinations, firstly by evaluating their visual acuity, subjective and objective refraction with and without cycloplegia, slight lamp evaluation, computerized topography, pupillometry, retina examination and measurement of intraocular pressure. Pachymetric values were measured with Orbscan IIz (Bausch – Lomb). Refractive surgery was done with LASIK under local anesthesia. Results: In this study 102 patients were treated with LASIK who were with different refractive anomalies. According to the group age 44 or 43.1% were of the age 20 – 29, 46 or 45.1% were of the age 30 – 39, 11 or 10.8% were 40 – 49 years of age and 1 or 1% were above the age of 50 +. Pachymetric before surgery in right eye was approximately 565.4 μm (DS+- 39.4), from 507 μm up to 678 μm, but after surgery it was approximately 497.5 μm (DS+-61.7) from 346 μm up to 644 μm. Pachymetric on the left eye before surgery was approximately 564.8 μm (DS+-41.5) from 504 μm up to 696 μm but after surgery it was approximately 498.3 μm (DS+-62.2), from 329 μm up to 646 μm. Pachymetric in both eyes before surgery was approximately 549.1 μm (DS+=73.9), from 263 μm up to 687 μm. Pachymetric on both eyes after surgery was approximately 496.9 μm (DS+-60.1), from 337.5 μm up to 645 μm. With the “ Paired T – test ” we have reached a significant statistical change between the pachymetric values in both eyes before and after the surgery (P

      PubDate: Sun, 22 Nov 2015 01:33:35 GMT
  • Comparison of Glucocorticoid (Budesonide) and Antileukotriene
           (Montelukast) Effect in Patients with Bronchial Asthma Determined with
           Body Plethysmography

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Njomza Lajqi, Ali Ilazi, Bashkim Kastrati, Hilmi Islami.
      Objective: Effect of glucocorticoids-budesonide and antileukotriene–montelukast in patients with bronchial asthma and bronchial increased reactivity was studied in this work. Methods: Parameters of the lung function are determined with Body plethysmography. Raw and ITGV were registered and specific resistance (SRaw) was also calculated. Results: Results of this research, in patients with bronchial asthma, indicate that glucocorticoids – budesonide (Pulmicort; 2 x 2 mg inh) has significant action (p< 0.01) on reduction of the specific resistance (SRaw) of airways, applied to the same patients 3 days after administration of montelukast, at home (2 x 10 mg). Three days after administration of the montelukast, antileukotriene medicine, at home, on the fourth day same patients administered a capsule of montelukast, 10 mg dose per os, and significantly (p < 0.05) reduced the increased bronchomotor tonus; and the effect of the control with salbutamol (beta2-adrenergic agonist) is effective in removal of the increased bronchomotor tonus, causing significant decrease of the resistance (Raw), respectively of the specific resistance (SRaw), (p < 0, 01). Conclusion: This suggests that the bronchodilator effect of glucocorticoids is more powerful than of the leukotriene, because glucocorticoids terminate the early stage of chemical mediator release (prostaglandins PgD2, SRS, and leukotriene LTC4, LTD4, LTE4 and Cytokinins also etc.) as powerful bronchoconstriction substances, whilst antileukotriene substances does not have this feature.

      PubDate: Sun, 22 Nov 2015 01:31:50 GMT
  • Interictal Electroencephalography (EEG) Findings in Children with Epilepsy
           and Bilateral Brain Lesions on Magnetic Resonance Imaging (MRI)

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Smail Zubcevic, Maja Milos, Feriha Catibusic, Sajra Uzicanin, Belma Krdzalic.
      Introduction: Neuroimaging procedures and electroencephalography (EEG) are basic parts of investigation of patients with epilepsies. Aim: The aim is to try to assess relationship between bilaterally localized brain lesions found in routine management of children with newly diagnosed epilepsy and their interictal EEG findings. Patients and methods: Total amount of 68 patients filled criteria for inclusion in the study that was performed at Neuropediatrics Department, Pediatric Hospital, University Clinical Center Sarajevo, or its outpatient clinic. There were 33 girls (48,5%) and 35 boys (51,5%). Average age at diagnosis of epilepsy was 3,5 years. Results: Both neurological and neuropsychological examination in the moment of making diagnosis of epilepsy was normal in 27 (39,7%) patients, and showed some kind of delay or other neurological finding in 41 (60,3%). Brain MRI showed lesions that can be related to antenatal or perinatal events in most of the patients (ventricular dilation in 30,9%, delayed myelination and post-hypoxic changes in 27,9%). More than half of patients (55,9%) showed bilateral interictal epileptiform discharges on their EEGs, and further 14,7% had other kinds of bilateral abnormalities. Frequency of bilateral epileptic discharges showed statistically significant predominance on level of p

      PubDate: Sun, 22 Nov 2015 01:30:25 GMT
  • The Event-related Potential P300 in Patients with Migraine

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Marina Titlic, Nikolina Ivica Mise, Irena Pintaric, Veljko Rogosic, Lucija Vanjaka-Rogosic, Mario Mihalj, Pavao Jurinovic, Ana Curkovi&#; Katic, Maja Andjelinovic.
      Objective: Recording of event-related potentials by using oddball paradigm of auditory P300 has yielded conflicting results in migraine. The aim of this study was to demonstrate that migraine patients have reduced P300 amplitude and prolonged P300 latency, suggesting alterations of the cognitive-evaluative component. Methods: We recruited 29 migraine patients (24 females; median age 40 years) and 29 healthy age- and gender-matched participants. Participants were subjected to the same testing procedures of auditory P300 by discrimination the target auditory stimulus from the frequent stimulus, and analyzing P300 target/frequent stimulus amplitudes, and P300 target/frequent stimulus latencies. Results: Patients with migraine don’t have prolonged P300 target stimulus latency, but have a longer P300 frequent stimulus latency for 17.5ms. Out of 29 participants with migraine 8 had pathological P300 target stimulus amplitude, and 19 had pathological P300 frequent stimulus amplitude. Conclusion: People with migraine have altered the P300 which indicates the presence of cognitive dysfunction in these patients and importance of early diagnosis and intervention to preventing any deterioration in cognitive functions.

      PubDate: Sun, 22 Nov 2015 01:28:55 GMT
  • Designing Decision Support System to Detect Drug Interactions Type 2

    • Abstract: 2015-11-24T23-17-18Z
      Source: Acta Informatica Medica
      Mehdi Rasoolimoghadam, Reza Safdari, Marjan Ghazisaeidi, MohammadReza Maharanitehrani, Shahram Tahmasebiyan.
      Background and Aim: Type II Diabetes is the most common diseases of metabolic disorders and the treatment of oral anti-diabetic drug use takes place But The problem of using multi-drug and interactions at the same time is an issue that has always been a major challenge And diagnosis of drug interactions, particularly in Diabetic patients due to the problem with the disease is very important. The purpose of this studying is, to design a clinical assistant decided to use this approach to determine the type II diabetes drug interactions this makes it easy for those who are active in the field. Materials and Methods: Study is Developmental that to determine the content of the system a self-made checklist was used. Checklist Validity and reliability has been confirmed by four professors. The Research community to determine the content of the system was country endocrine that are 124 people.  The sample size was calculated using Cochran that was 57 people. The Score of checklist was calculated in SPSS version 20 .finally, the checklist was approved by at least 70% points. The system by using Microsoft SQL server 2008 and visual Studio 2012 development environment was designed in In the end, In order to evaluate the software to determine the level of satisfaction, usability and ease of use, designed systems sharing with all Medical Informatics students of Tehran University of Medical Sciences. For this purpose a self-made questionnaire was used. Questionnaire Validity has been confirmed by four professors and reliability was assessed by Cronbach method. Results: The results of the survey are showing that the majority of students found out and believed the software is useful and easy to use and generally expressed their satisfaction software. Conclusions: The methodology provides a suitable approach for analysis and modeling of data in the medical field and the performance is good.

      PubDate: Sun, 22 Nov 2015 01:27:33 GMT
  • The Most Influential Scientists in the Development of Medical Informatics
           (8): Jean Raoul Scherrer

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Mon, 05 Oct 2015 13:03:25 GMT
  • Chromatography as Method for Analytical Confirmation of Paracetamol in
           Postmortem Material Together with Psychoactive Substances

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Jasmina Biscevic-Tokic, Nedim Tokic, Elma Ibrahimpasic.
      Introduction: Paracetamol (Acetaminophen) in addition to aspirin is the most commonly used analgesic and antipyretic medication by millions of patients worldwide. It is an example that paracetamol as medicine that in the world is provided without a doctor’s prescription, can lead to death. Today paracetamol became an integral part of a heroin mixture and is very popular at the street market. The main reason for this is that it can be obtained without a prescription, it is cheap, and by most people well tolerated without side effects. It is probably used for “cutting” the pure heroin, as it says in the jargon, and in that manner from small amount of pure drug is obtained greater amount, which is then sold on the street. The goal is to identify presence of paracetamol, by analytical method of gas chromatography mass spectrometer (GC-MS) in postmortem material together with psychoactive substances. Material and methods: For chemical-toxicological analysis is used biological material collected trough autopsy of 20 deceased people, suspected to have died due to psychoactive substance overdose. All received samples are stored at -20 ° C until analysis at our laboratory. From processed 47 samples that were analyzed in the period from 2014 to 2015, 19 are blood samples, urine 19, 3 samples of stomach contents, and 6 samples of bile content. Deceased were middle-aged, of which only 7 were female. The tested samples were processed according to two methods of extraction. Extraction by XAD-2 resin, and the extraction by the method of salting out with sodium tungstate. Extracts of the samples were then dissolved in chloroform and continued analysis at the analytical instrument. Identification of the paracetamol presence, in the test biological samples is demonstrated by the technique of gas chromatography with mass spectometry (hereinafter referred to as GC-MS). The technique of GC-MS is a selective, sensitive and reliable, and is therefore considered a “gold standard” for determining the drug, and the drug substance. Used GC-MS instrument was an Agilent 7890A with helium as the carrier gas. Results: The analysis of blood samples, urine, bile and stomach contents, obtained after the autopsy of deceased persons, by using gas chromatography with mass spectrometry, in analytical manner confirmed the fact that paracetamol is a very common component of psychoactive substances poisoning. In our assay of samples we detected psychoactive substances (heroin, codeine, morphine, sertraline, diazepam), and almost all were found in the combination with paracetamol, indicating the poor quality of illicit drugs sold on the market. Discussion: Paracetamol (Acetaminophen) is a very common component in mixtures of street drugs. Such mixtures almost anyone can afford, but the very quality of these drugs has become extremely low, because it does not sell the pure substance, but is mixed with various medications. According to research Pantazia et al. the heroin mixture proportion of the heroin is very small so a lot of that mixture has only 3% of heroin, a large number of cases can be only 1% of pure heroin. Most of the time it replaces caffeine and paracetamol. According to the Risser et al. reason why acetaminophen component is present in these mixtures is because it can be purchased without a prescription, it is cheap, well tolerated by most people and shows no side effects. Conclusion: When we talk about illegal drugs, we must emphasize the fact that there is no quality control, or the composition of the drug. The composition of the drug purchased on the black market is still unknown to potential user. While reaching the final drug users it pass through many hands, and at each step something is added to increase earnings. Most often present additives or impurities in narcotic drugs that are added are caffeine, ephedrine, acetaminophen, acetylsalicylic acid (aspirin) and additives such as powders, cement and chalk.

      PubDate: Mon, 05 Oct 2015 13:01:20 GMT
  • Development of Performance Dashboards in Healthcare Sector: Key Practical

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Marjan Ghazisaeidi, Reza Safdari, Mashallah Torabi, Mahboobeh Mirzaee, Jebraeil Farzi, Azadeh Goodini.
      Background: Static nature of performance reporting systems in health care sector has resulted in inconsistent, incomparable, time consuming, and static performance reports that are not able to transparently reflect a round picture of performance and effectively support healthcare managers’ decision makings. So, the healthcare sector needs interactive performance management tools such as performance dashboards to measure, monitor, and manage performance more effectively. The aim of this article was to identify key issues that need to be addressed for developing high-quality performance dashboards in healthcare sector. Methods: A literature review was established to search electronic research databases, e-journals collections, and printed journals, books, dissertations, and theses for relevant articles. The search strategy interchangeably used the terms of “dashboard”, “performance measurement system” and “executive information system” with the term of “design” combined with operator “AND”. Search results (n=250) were adjusted for duplications, screened based on their abstract relevancy and full-text availability (n=147) and then assessed for eligibility (n=40). Eligible articles were included if they had explicitly focused on dashboards, performance measurement systems or executive information systems design. Finally, 28 relevant articles included in the study. Results: Creating high-quality performance dashboards requires addressing both performance measurement and executive information systems design issues. Covering these two fields, identified contents were categorized to four main domains: KPIs development, Data Sources and data generation, Integration of dashboards to source systems, and Information presentation issues. Conclusion: This study implies the main steps to develop dashboards for the purpose of performance management. Performance dashboards developed on performance measurement and executive information systems principles and supported by proper back-end infrastructure will result in creation of dynamic reports that help healthcare managers to consistently measure the performance, continuously detect outliers, deeply analyze causes of poor performance, and effectively plan for the future.

      PubDate: Mon, 05 Oct 2015 12:59:37 GMT
  • Designing of Intelligent Multilingual Patient Reported Outcome System

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Faramarz Pourasghar, Yeganeh Partovi.
      Background: By self-reporting outcome procedure the patients themselves record disease symptoms outside medical centers and then report them to medical staff in specific periods of time. One of the self-reporting methods is the application of interactive voice response (IVR), in which some pre-designed questions in the form of voice tracks would be played and then the caller responses the questions by pressing phone’s keypad bottoms. Aim: The present research explains the main framework of such system designing according to IVR technology that is for the first time designed and administered in Iran. Methods: Interactive Voice Response system was composed by two main parts of hardware and software. Hardware section includes one or several digital phone lines, a modem card with voice playing capability and a PC. IVR software on the other hand, acts as an intelligent control center, records call information and controls incoming data. Results: One of the main features of the system is its capability to be administered in common PCs, utilizing simple and cheap modems, high speed to take responses and it’s appropriateness to low literate patients. The system is applicable for monitoring chronic diseases, cancer and also in psychological diseases and can be suitable for taking care of elders and Children who require long term cares. Other features include user-friendly, decrease in direct and indirect costs of disease treatment and enjoying from high level of security to access patients’ profiles. Conclusions: Intelligent multilingual patient reported outcome system (IMPROS) by controlling diseases gives the opportunity to patients to have more participation during treatment and it improves mutual interaction between patient and medical staff. Moreover it increases the quality of medical services, Additional to empowering patients and their followers.

      PubDate: Mon, 05 Oct 2015 12:57:28 GMT
  • Quantitative and Qualitative Evaluation of The Structural Designing of
           Medical Informatics Dynamic Encyclopedia

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Reza Safdari, Leila Shahmoradi, Molouk-sadat Hosseini-beheshti, Ahmadreza Farzaneh Nejad, Mohammad Hosseiniravandi.
      Introduction: Encyclopedias and their compilation have become so prevalent as a valid cultural medium in the world. The daily development of computer industry and the expansion of various sciences have made indispensable the compilation of electronic, specialized encyclopedias, especially the web-based ones. Materials and Methods: This is an applied-developmental study conducted in 2014. First, the main terms in the field of medical informatics were gathered using MeSH Online 2014 and the supplementary terms of each were determined, and then the tree diagram of the terms was drawn based on their relationship in MeSH. Based on the studies done by the researchers, the tree diagram of the encyclopedia was drawn with respect to the existing areas in this field, and the terms gathered were put in related domains. Findings: In MeSH, 75 preferred terms together with 249 supplementary ones were indexed. One of the informatics’ sub-branches is biomedical informatics and health which itself consists of three sub-divisions of bioinformatics, clinical informatics, and health informatics. Medical informatics which is a subdivision of clinical informatics has developed from the three fields of medical sciences, management and social sciences, and computational sciences and mathematics. Results and Discussion: Medical Informatics is created of confluence and fusion and applications of the three major scientific branches include health and biological sciences, social sciences and management sciences, computing and mathematical sciences, and according to that the structure of MeSH is weak for future development of Encyclopedia of Medical Informatics.

      PubDate: Mon, 05 Oct 2015 12:55:42 GMT
  • Quantitative and Qualitative Evaluation of Iranian Researchers’
           Scientific Production in Dentistry Subfields

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Mousa Yaminfirooz, Mina Motallebnejad, Hemmat Gholinia, Somayeh Esbakian.
      Background: As in other fields of medicine, scientific production in the field of dentistry has significant placement. This study aimed at quantitatively and qualitatively evaluating Iranian researchers’ scientific output in the field of dentistry and determining their contribution in each of dentistry subfields and branches. Methods: This research was a scientometric study that applied quantitative and qualitative indices of Web of Science (WoS). Research population consisted of927indexed documents published under the name of Iran in the time span of 1993-2012 which were extracted from WoS on 10 March 2013. The Mann-Whitney test and Pearson correlation coefficient were used to data analyses in SPSS 19. Results: 777 (83. 73%) of indexed items of all scientific output in WoS were scientific articles. The highest growth rate of scientific productionwith90% belonged to endodontic sub field. The correlation coefficient test showed that there was a significant positive relationship between the number of documents and their publication age (P < 0. 0001). There was a significant difference between the mean number of published articles in the first ten- year (1993-2003) and that of the second one (2004-2013), in favor of the latter (P = 0. 001). Conclusions: The distribution frequencies of scientific production in various subfields of dentistry were very different. It needs to reinforce the infrastructure for more balanced scientific production in the field and its related subfields.

      PubDate: Mon, 05 Oct 2015 12:53:40 GMT
  • A Comparison of Logistic Regression Model and Artificial Neural Networks
           in Predicting of Student’s Academic Failure

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Saeed Hosseini Teshnizi, Sayyed Mohhamad Taghi Ayatollahi.
      Background and objective: Artificial Neural Networks (ANNs) have recently been applied in situations where an analysis based on the logistic regression (LR) is a standard statistical approach; direct comparisons of the results, however, are seldom attempted. In this study, we compared both logistic regression models and feed-forward neural networks on the academic failure data set. Methods: The data for this study included 18 questions about study situation of 275 undergraduate students selected randomly from among nursing and midwifery and paramedic schools of Hormozgan University of Medical Sciences in 2013. Logistic regression with forward method and feed forward Artificial Neural Network with 15 neurons in hidden layer were fitted to the dataset. The accuracy of the models in predicting academic failure was compared by using ROC (Receiver Operating Characteristic) and classification accuracy. Results: Among nine ANNs, the ANN with 15 neurons in hidden layer was a better ANN compared with LR. The Area Under Receiver Operating Characteristics (AUROC) of the LR model and ANN with 15 neurons in hidden layers, were estimated as 0.55 and 0.89, respectively and ANN was significantly greater than the LR. The LR and ANN models respectively classified 77.5% and 84.3% of the students correctly. Conclusion: Based on this dataset, it seems the classification of the students in two groups with and without academic failure by using ANN with 15 neurons in the hidden layer is better than the LR model.

      PubDate: Mon, 05 Oct 2015 12:52:25 GMT
  • The Use of an Adapted Health IT Usability Evaluation Model (Health-ITUEM)
           for Evaluating Consumer Reported Ratings of Diabetes mHealth Applications:
           Implications for Diabetes Care and Management

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Mowafa S. Househ, Mamdouh M. Shubair, Faisel Yunus, Amr Jamal, Bakheet Aldossari.
      Background: The aim of this paper is to present a usability analysis of the consumer ratings of key diabetes mHealth applications using an adapted Health IT Usability Evaluation Model (Health-ITUEM). Methods: A qualitative content analysis method was used to analyze publicly available consumer reported data posted on the Android Market and Google Play for four leading diabetes mHealth applications. Health-ITUEM concepts including information needs, flexibility/customizability, learnability, performance speed, and competency guided the categorization and analysis of the data. Health impact was an additional category that was included in the study. A total of 405 consumers’ ratings collected from January 9, 2014 to February 17, 2014 were included in the study. Results: Overall, the consumers’ ratings of the leading diabetes mHealth applications for both usability and health impacts were positive. The performance speed of the mHealth application and the information needs of the consumers were the primary usability factors impacting the use of the diabetes mHealth applications. There was also evidence on the positive health impacts of such applications. Conclusions: Consumers are more likely to use diabetes related mHealth applications that perform well and meet their information needs. Furthermore, there is preliminary evidence that diabetes mHealth applications can have positive impact on the health of patients.

      PubDate: Mon, 05 Oct 2015 12:51:00 GMT
  • Evaluation of Pharyngeal Space in Different Combinations of Class II
           Skeletal Malocclusion

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Jay Soni, Tarulatha R. Shyagali, Deepak P. Bhayya, Romil Shah.
      Objectives: The study was aimed to evaluate the pharyngeal airway linear measurements of untreated skeletal class II subjects with normal facial vertical pattern in prognathic maxilla with orthognathic mandible and orthognathic maxilla with retrognathic mandible. Materials and method: the sample comprised of lateral Cephalograms of two groups (30 each) of class II malocclusion variants. Group 1 comprised of class II malocclusion with prognathic maxilla and orthognathic mandible, whereas group 2 comprised of class II malocclusion with orthognathic maxilla and retrognathic mandible. Each group was traced for the linear measurements of the pharyngeal airway like the oropharynx, nasopharynx and soft palate. The obtained data was subjected to independent t test and the Mann Whitney test to check the difference between the two groups and within the groups respectively. Results: there was significant difference between all the linear measurements at the soft palate region and the distance between the tip of soft palate to its counter point on the pharyngeal wall in oropharynx region (p-ppm). Conclusion: the pharyngeal airway for class II malocclusion with various combination in an average growth pattern adult showed significant difference. The present results suggested, that the pharyngeal airway space might be the etiological factor for different sagittal growth pattern of the jaws and probable usage of different growth modification appliance can influence the pharyngeal airway.

      PubDate: Mon, 05 Oct 2015 12:49:39 GMT
  • Evaluation of the Hemodynamic Response to Endotracheal Intubation
           Comparing the Airtraq® with Macintosh Laryngoscopes in Cardiac
           Surgical Patients

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Aleksandra Gavrilovska-Brzanov, Mohhamed Al Jarallah, Andrea Cogliati, Maja Mojsova-Mijovska, Dragan Mijuskovic, Dimce Slaveski.
      Introduction: Cardiac patients are more prone to develop hemodynamic instability on induction of anesthesia and endotracheal intubation. The Airtraq® ® optical laryngoscope is a single-use rigid video laryngoscope that has been developed to facilitate tracheal intubation. There are limited studies comparing differences in the circulatory responses to Airtraq® and direct Macintosh larynngoscopy in cardiac patients. Aim: The purpose of our study was to evaluate whether there was clinically significant difference between the hemodynamic response to orotracheal intubation guided by either of the two devices (Airtraq® and Macintosh laryngoscopes) in patients who underwent coronary artery bypass grafting surgery. Material and methods: In this clinical study we analyzed the hemodynamic response to endotracheal intubation performed with Airtraq® or Macintosh laryngoscopes in patients who underwent elective coronary artery bypass graft surgery under general anesthesia. Results: We analyzed: blood pressure (systolic, diastolic, mean), heart rate and peripheral oxygen saturation (all notified before induction in anesthesia, immediately after induction, at the time of intubation and thereafter one and five minutes after intubation). We also recorded the maximal values of blood pressure and heart rate, as well as calculated the product of heart rate and systolic blood pressure. There were statistically significant differences in the hemodynamic response between the groups. At the time of intubation, there was significant inter-group difference in heart rate, systolic, diastolic and mean blood pressure. Endotracheal intubation with Macintosh laryngoscope was accompanied by significant increase in blood pressure and heart rate compared to Airtraq® group. Conclusion: The Airtraq® laryngoscope performed better than the Macintosh laryngoscope in terms of hemodynamic to the patient undergoing routine coronary artery bypass graft surgery.

      PubDate: Mon, 05 Oct 2015 12:48:21 GMT
  • Echocardiography Differences Between Athlete’s Heart Hearth and
           Hypertrophic Cardiomyopathy

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Amir Kreso, Fahir Barakovic, Esad Medjedovic, Amila Halilbasic, Muhamed Klepic.
      Introduction: Among long term athletes there is always present hypertrophy of the left ventricle walls as well as increased cardiac mass. These changes are the result of the heart muscle adaptation to load during the years of training, which should not be considered as pathology. In people suffering from hypertrophic cardiomyopathy (HCM), there is also present hypertrophy of the left ventricle walls and increased mass of the heart, but these changes are the result of pathological changes in the heart caused by a genetic predisposition for the development HCM of. Differences between myocardial hypertrophy in athletes and HCM are not clearly differentiated and there are always dilemmas between pathological and physiological hypertrophy. The goal of the study is to determine and compare the echocardiographic cardiac parameters of longtime athletes to patients with hypertrophic cardiomyopathy. Material and methods: The study included 60 subjects divided into two groups: active athletes and people with hypertrophic cardiomyopathy. Results: Mean values of IVSd recorded in GB is IVSd=17.5 mm (n=20, 95% CI, 16.00–19.00 mm), while a significantly smaller mean value is recorded in GA, IVSd=10.0 mm (n=40, 95% CI, 9.00-11.00 mm). The mean value of the left ventricle in diastole (LVDd) recorded in the GA is LVDd=51 mm (n=40; 95% CI, 48.00 to 52.00 mm), while in the group with hypertrophic cardiomyopathy (GB) mean LVDd value is 42 mm (n=20; 95% CI, 40.00 to 48.00 mm). The mean value of the rear wall of the left ventricle (LVPWd) recorded in the GA is LVDd=10 mm (n=40; 95% CI, 9.00-10.00 mm) while in the group with hypertrophic cardiomyopathy (GB) mean LVDd is 14 mm (n=20; 95% CI, 12.00 to 16.00 mm). The mean of the left ventricle during systole (LVSD) observed in GA is LVSD=34 mm (n=40; 95% CI, 32.00 to 36.00 mm), while in the group with hypertrophic cardiomyopathy (GB) mean LVSD is 28 mm (n=20; 95% CI, 24.00 to 28.83 mm). The mean ejection fraction (EF%) observed in GA is EF=60% (n=40; 95% CI, 56.41 to 63.00%), while in the group with hypertrophic cardiomyopathy (GB) mean EF value is 69% (n=20; 95% CI, 62.00 to 70.83 mm). Somewhat higher mean diastolic left ventricular function (E/A) was observed in GA, E/A=1.76±0.15, and lower average values in the group with hypertrophic cardiomyopathy (GB) E/A=0.78±0.02. Conclusion: Mean values of parameters: intraventricular septum thickness in diastole (IVSd), the thickness of the rear wall of the left ventricle (LVPWd), the diameter of the left ventricle during systole (LVSD) were statistically different between groups of athletes (GA) compared to the group of patients with hypertrophic cardiomyopathy (GB).

      PubDate: Mon, 05 Oct 2015 12:45:53 GMT
  • Contrast Media Injector Technology - Renal Safety During Coronarography

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Ermina Mujicic, Ekrem Kevric, Senija Rasic, Amina Selimovic, Nermir Granov, Dinka Music.
      Aim: This study sought to assess whether the volume and osmolarity of contrast media (CM) influences the occurrence of contrast induced nephropathy (CIN) following coronarography procedure. CIN can be defined as an increase in the serum concentration of creatinine greater than a 25% from baseline during the period of 12 to 48 hours after the administration of radiocontrast media. Material and methods: We examined 100 patients without diabetes with serum creatinine concentration from 45 mmol/l to 141 mmol/l and 100 patients with diabetes with serum creatinine concentration from 46 mmol/l to 161 mmol/l who underwent coronary angiography. During procedure they received iso-osmolar contrast medium, Visipaque 320 (iodixanol-320), for group without diabetes from 40 to 340 ml and for group with diabetes from 49 to 310 ml. Results: CIN occurred in 27 (13,5%) of the 200 study patients. There was a trend toward higher prevalence of CIN (16% vs.11%, p = 0.086) in the diabetic group compared with the non-diabetic group. Patient with diabetes received less contrast media, they are younger but number patients with CIN are higher. Conclusion: Increasing contrast media dose is associated with the occurrence of CIN following coronarography. But, another risk factors like diabetes mellitus, old age, male sex and preexisting kidney disease have influence of developing CIN after coronarography.

      PubDate: Mon, 05 Oct 2015 12:44:46 GMT
  • Significance of Sonographically Demonstrated Ureteral Dilatation in
           Evaluation of Vesicoureteral Reflux Verified with Voiding Urosonography in
           Children with Urinary Tract Infection

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Aladin Carovac, Sandra Vegar Zubovic, Marklena Carovac, Irmina Sefic Pasic.
      Objectives. The aim of this study was to determine sensitivity, specificity, and predictive values of sonographically demonstrated ureteral dilatation in detecting vesicoureteral reflux (VUR). Methods. Ethical approval from the Ethical Committee of Clinical Center University of Sarajevo and parental consent were obtained for this prospective study involving 120 children with history of urinary tract infections (UTIs). Ultrasound examination included the evaluation of the urinary tract, with a special emphasis on evaluation of ureteral dilatation. Voiding urosonography (VUS) was carried out according to a standard protocol with the use of ultrasound contrast agent Sono Vue of second generation. Ureteral diameter greater than 3 mm was considered pathological. Proven VUR was graded into one of three stages. Results. Infectio tracti urinarii recidivans was referral diagnosis in the majority of patients. The average age of patients was 4.33 ± 3.88 years (from 2 months to 16 years of age). VUS findings were normal in 59 (49.2%), and pathological in 61 (50.8%) patients. Statistical analysis showed significant correlation between type and grade of VUR. Our data confirmed predominance of VUR in females and in children under the age of 5. Statistically significant correlation between ureteral dilatation and the existence of VUR was found, with relatively high sensitivity (67.2%), specificity (81.4%), and high positive (78.8%) and negative predictive value (70.6%), total diagnostic accuracy of 74.2% in detecting VUR, and significantly increased probability (20 – 25%) of detecting VUR in patients with sonographically confirmed ureteral dilatation. Conclusion. Sonographically confirmed ureteral dilatation can be used as a predictor of VUR in children with UTIs, and in combination with other predictors, might find a place in an evidence-based selective strategy in children with suspected VUR.

      PubDate: Mon, 05 Oct 2015 12:42:45 GMT
  • Influence of the Inherited Glucose-6-phosphate Dehydrogenase Deficiency on
           the Appearance of Neonatal Hyperbilirubinemia in Southern Croatia

    • Abstract: 2015-10-06T23-18-19Z
      Source: Acta Informatica Medica
      Anet Papazovska Cherepnalkovski, Eugenija Marusic, Katica Piperkova, Bernarda Lozic, Ana Skelin, Todor Gruev, Vjekoslav Krzelj.
      Background: Neonatal hyperbilirubinemia is a common clinical manifestation of the inherited glucose-6-phosphate dehydrogenase (G6PD) deficiency. Aim of the study: The aim of this study was to investigate the influence of the inherited G6PD deficiency on the appearance of neonatal hyperbilirubinemia in southern Croatia. Methods: The fluorescent spot test (FST) was used in a retrospective study to screen blood samples of 513 male children who had neonatal hyperbilirubinemia, of unknown cause, higher than 240 µmol/L. Fluorescence readings were performed at the beginning and at the fifth and tenth minute of incubation and were classified into three groups: bright fluorescence (BF), weak fluorescence (WF) and no fluorescence (NF). Normal samples show bright fluorescence. All NF and WF samples at the fifth minute were quantitatively measured using the spectrophotometric method. Results: Bright fluorescence was present in 461 patients (89.9%) at the fifth minute. The remaining 52 (10.1%) were quantitatively estimated using the spectrophotometric method. G6PD deficiency was observed in 38 patients (7.4%). Conclusions: Prevalence rate of G6PD deficiency among male newborns with hyperbilirubinemia in southern Croatia is significantly higher (p < 0.01) compared with the previously reported prevalence rate among male in general population of southern Croatia (0.75%). We recommend FST to be performed in hyperbilirubinemic newborns in southern Croatia.

      PubDate: Mon, 05 Oct 2015 12:41:17 GMT
  • Biographical Lexicon of Medical Informatics

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Gjuro Dezelic.
      Author: Prof Izet Masic, MD, PhD Publisher: AVICENA, d.o.o., Sarajevo, year 2015., 300 pages, hard cover. ISBN 978-9958-720-57-4; COBISS.BH-ID 21884422

      PubDate: Thu, 30 Jul 2015 07:25:34 GMT
  • 13th International Conference on Informatics, Management and Technology in
           Healthcare, Athens, Greece, 9-11 July, 2015

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Thu, 30 Jul 2015 07:24:23 GMT
  • International Joint Meeting EuroMISE 2015 Prague, Czech Republic, June
           16-18, 2015

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Thu, 30 Jul 2015 07:21:18 GMT
  • The Most Influential Scientists in the Development of the Medical
           Informatics (7): Shigekoto Kaihara

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Thu, 30 Jul 2015 07:19:39 GMT
  • MRI Findings of Talocalcaneal Coalition: Two Case Reports

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Ayşe Umul.
      Introduction: Tarsal coalition is abnormal fusion of two or more tarsal bones and is a common cause of foot pain. There are osseous, cartilaginous and fibrous subtypes. Calcaneonavicular and talocalcaneal coalitions are more frequent. Radiography is the primary diagnostic tool, however CT and MRI are precious examinations for differential diagnosis of osseous /non-osseous coalitions separations. Furthermore, cross-sectional imaging methods indicate the extension and secondary degenerative joint changes. Case reports: The detection of bone marrow of edema in the articulation area is valuable for diagnosis Hereby, we present two cases, 24 years old female and 35 years old male, with the diagnosis of talocalcaneal coaliation. We also discuss MRI and radiographic findings.

      PubDate: Thu, 30 Jul 2015 07:17:18 GMT
  • Suggested Minimum Data Set for Speech Therapy Centers Affiliated to Tabriz
           University of Medical Sciences

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Shahla Damanabi, Shawbo Abdolnejad, Gelavizh Karimi.
      Background: The minimum data considered as a conceptual framework, based on the achievement of effectiveness indicators and it ensures to access of precise and clear health data. The aims of the present study were identified and proposed a data element set of speech therapy centers affiliated with Tabriz University of Medical Sciences. Material and Methods: This study that was cross – sectional type, performed in 9 speech therapy clinic from medical university in 2014. Firstly, the minimum data elements set evaluated using the check list in these centers. Using the findings from the first step and survey of internal and external documentation forms, designed a questionnaire containing a minimum data speech therapy files and it shared between 36 Speech therapy experts using 5 options of Likert scale. Validity of questionnaire was examined through its validity and reliability of content by retest. For data analysis, data processing was performed using descriptive statistics by SPSS21 software. Results: The minimum data set for speech therapy were divided into two categories: clinical and administrative data. The Name and surname, date of birth, gender, address, telephone number, date of admission and the number of treatments, the patient’s complaint, the time of occurrence of injury or disorder, reason and age of disease considered as the most important elements for management data and health history. For the most important elements of clinical information were selected Short-term and long-term aims and development of speech history .Conclusion: The design and implementation of suitable data collection of speech therapy for gathering of data, we recommended planning for the control and prevention of speech disorders to providing high quality and good care of patient in speech therapy centers.

      PubDate: Thu, 30 Jul 2015 07:15:54 GMT
  • Hemodialysis Adequacy Monitoring Information System: Minimum Data Set and
           Capabilities Required

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Mohamad Jebraeily, Marjan Ghazisaeidi, Reza Safdari, Khadijeh Makhdoomi, Bahlol Rahimi.
      Introduction: In dialysis centers both nephrologists and nurses are faced with the challenge of ensuring reliable and efficient care accordance with the clinical guideline. Hemodialysis adequacy monitoring information system therefore enable the automation of tasks, which ultimately allows doctors and nursing staff more time to dedicate to the individual treatment of patients. Development of the information systems in healthcare has made the use of the Minimum data set inevitable. The purpose of this study was determined MDS and capabilities required in hemodialysis adequacy monitoring information system. Method and materials: This is a cross-sectional survey conducted with participation of 320 nephrology specialists in 2015. Data were collected using an electronic questionnaire which was estimated as both reliable and valid. The data were analyzed by SPSS software descriptive statistics and analytical statistics. Results: Overall 42 data elements were determined as final set in 4 major categories (patient demographics, medical history, treatment plan and hemodialysis adequacy). The most capabilities required of hemodialysis information system were related to calculate of dialysis adequacy Index (4.80), advice optimal dose of dialysis for each patient (4.63), Easy access to information system without restrictions of time and place (4.61), providing alerts when dialysis adequacy index below the standard (4.55) and Interchange to other information systems in hospitals (4.46) respectively. Conclusion: In design and implementation of information systems focus on MDS and identification IS capabilities based on the users’ needs, due to the wide participation users and also the success of the information system. Therefore it is necessary that MDS evaluated carefully with regard to the intended uses of the data. Also information systems based on capabilities the ability to meet the needs of their users.

      PubDate: Thu, 30 Jul 2015 07:13:30 GMT
  • Inhibition on JAK-STAT3 Signaling Transduction Cascade Is Taken by
           Bioactive Peptide Alpha-S2 Casein Protein from Goat Ethawah Breed Milk

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Rista Nikmatu Rohmah, Ferlany Hardiyanti, Fatchiyah Fatchiyah.
      Background: RA is a systemic inflammatory disease that causes developing comorbidity conditions. This condition can cause by overproduction of pro-inflammatory cytokine. In a previous study, we have found bioactive peptide CSN1S2 from Ethawah goat milk for anti-inflammatory for repair the ileum destruction. However, the signaling transduction cascade of bioactive peptides inhibits inflammation still not clear yet. Therefore, we analyzed the signaling transduction cascade via JAK-STAT3 pathway by in vivo and in silico. Methods: The ileum was isolated DNA and amplification with specific primer. The sequence was analyzed using the Sanger sequencing method. Modeling 3D-structure was predicted by SWISS-MODEL and virtual interaction was analyzed by docking system using Pymol and Discovery Studio 4.0 software. Results: This study showed that STAT3 has target gene 480bp. The normal group and normal treating- CSN1S2 of goat milk have similarity from gene bank. Whereas, RA group had transversion mutation that the purine change into pyrimidine even cause frameshift mutation. Interestingly, after treating with the CSN1S2 protein of goat milk shows reverse to the normal acid sequence group. Based on in silico study, from eight peptides, only three peptides of CSN1S2 protein, which carried by PePT1 to enter the small intestine. The fragments are PepT1-41-NMAIHPR-47; PepT1-182-KISQYYQK-189 and PepT1-214-TNAIPYVR-221. We have found just one bioactive peptide of f182-KISQYYQK-189 is able bind to STAT3. The energy binding of f182-KISQYYQK-189 and RA-STAT3 amino acid, it was Σ = -402.43 kJ/mol and the energy binding of f182-KISQYYQK-189 and RAS-STAT3 amino acid is decreasing into Σ = -407.09 kJ/mol. Conclusion: This study suggested that the fragment 182-KISQYYQK-189 peptides from Ethawah goat milk may act as an anti-inflammatory agent via JAK-STAT3 signal transduction cascade at the cellular level.

      PubDate: Thu, 30 Jul 2015 07:12:19 GMT
  • Regulation by Phloroglucinol of Nrf2/Maf-Mediated Expression of
           Antioxidant Enzymes and Inhibition of Osteoclastogenesis via the
           RANKL/RANK Signaling Pathway: In Silico study

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Agus Hadian Rahim, Bambang Setiawan, Firli Rahmah Primula Dewi, Zairin Noor.
      Introduction: Phloroglucinol is an antioxidant compound with many positive effects on health. The purpose of this study was to determine the role of phloroglucinol in osteoclastogenesis via the RANKL/RANK signaling pathway and the activity of the transcription factor Nrf2. Material and methods: Analysis was performed in silico using the primary method of docking by the use of Hex 8.0 software and Haddock web server. Analysis of interactions was then performed to determine interactions between the ligand and its receptors by using the software LigPlus and LigandScout 3.1. Results: Results indicated that phloroglucinol compound was thought to inhibit osteoclastogenesis via three mechanisms: inhibiting RANKL−RANK interaction, sustaining the RANKL−OPG bond, and increasing the activity of the transcription factor Nrf2.

      PubDate: Thu, 30 Jul 2015 07:10:41 GMT
  • Electronic Health Record for Intensive Care based on Usual Windows Based

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Arnaud Reper, Pascal Reper.
      Background and objectives: In Intensive Care Units, the amount of data to be processed for patients care, the turn over of the patients, the necessity for reliability and for review processes indicate the use of Patient Data Management Systems (PDMS) and electronic health records (EHR). To respond to the needs of an Intensive Care Unit and not to be locked with proprietary software, we developed an EHR based on usual software and components. Methods: The software was designed as a client–server architecture running on the Windows operating system and powered by the access data base system. The client software was developed using Visual Basic interface library. The application offers to the users the following functions: medical notes captures, observations and treatments, nursing charts with administration of medications, scoring systems for classification, and possibilities to encode medical activities for billing processes. Results: Since his deployment in September 2004, the EHR was used to care more than five thousands patients with the expected software reliability and facilitated data management and review processes. Communications with other medical software were not developed from the start, and are realized by the use of basic functionalities communication engine. Further upgrade of the system will include multi-platform support, use of typed language with static analysis, and configurable interface. Conclusion: The developed system based on usual software components was able to respond to the medical needs of the local ICU environment. The use of Windows for development allowed us to customize the software to the preexisting organization and contributed to the acceptability of the whole system.

      PubDate: Thu, 30 Jul 2015 07:08:27 GMT
  • Developing an Intelligent System for Diagnosis of Asthma Based on
           Artificial Neural Network

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Behrouz Alizadeh, Reza Safdari, Maryam Zolnoori, Azadeh Bashiri.
      Introduction: Lack of proper diagnosis and inadequate treatment of asthma, leads to physical and financial complications. This study aimed to use data mining techniques and creating a neural network intelligent system for diagnosis of asthma. Methods: The study population is the patients who had visited one of the Lung Clinics in Tehran. Data were analyzed using the SPSS statistical tool and the chi-square Pearson’s coefficient was the basis of decision making for data ranking. The considered neural network is trained using back propagation learning technique. Results: According to the analysis performed by means of SPSS to select the top factors, 13 effective factors were selected, in different performances, data was mixed in various forms, so the different modes was made for training the data and testing networks and in all different modes, the network was able to predict correctly 100% of all cases. Conclusion: Using data mining methods before the design structure of system, aimed to reduce the data dimension and the optimum choice of the data, will lead to a more accurate system. So considering the data mining approaches due to the nature of medical data is necessary.

      PubDate: Thu, 30 Jul 2015 07:07:04 GMT
  • The Webometric Status of Isfahan University of Medical Sciences, Iran

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Behjat Taheri, Roghayeh Ghazavi, Arash Zahed, Zahra Otroj, Elahe Mazaheri, Nayere-Sadat Soleimanzade-Najafi.
      Background: Webometrics refers to the quantitative study of science production, application, structure and technology in the cyber environment. Impact analysis, website collaboration, and recognition of core websites are regarded as the most practical advantages of webometrics. Furthermore, webometrics is applied in ranking studies for universities and academic institutes. This serves as an internationally approved means of academic ranking worldwide. Our study aimed to evaluate the webometric status of Isfahan University of Medical Sciences (IUMS) and its place in the Webometric Ranking of World Universities. We also tried to comment on how to improve the university’s webometric rank at national, regional, and international levels. Material and Methods: This was a descriptive cross-sectional study including all websites of Iranian universities. Census sampling was applied to cover all Iranian university websites. Then the websites were evaluated according to the latest criteria for the international webometric ranking methodology (Cyberometric Lab, July 2012) and their webometric rank at the international level as well as the changes in the rank between July 2012 and January 2013 were analyzed. The webometric rank of IUMS was compared with other medical universities at different levels as well. Findings: According to the findings, from July 2012 to January 2013, IUMS webometric rank improved by 707, 5 and 2 at international, national and ministerial levels, respectively. Moreover, the rank of IUMS for openness rose from 4477 to 193 during the mentioned period (∆ 4284). In excellence, the university rank did not change sensibly (1537 /1538). In the same period, the rank in presence shifted from 1137 to 1091. Meanwhile, growth in website impact was negative as the university impact rank declined from 3369 to 3393. Conclusion: It seems that impact as the most influential ranking indicator fails to grow proportionately as other factors of IUMS website. This is potentially due to the content language (Farsi) which is an important barrier to easy retrieval of information by non-Farsi speakers. However, the scientific content and SEO (Search Engine Optimization) standards of the website need serious improvement.

      PubDate: Thu, 30 Jul 2015 07:01:38 GMT
  • A Map for Clinical Laboratories Management Indicators in the Intelligent

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Zahra Azadmanjir, Mashallah Torabi, Reza Safdari, Maryam Bayat, Fatemeh Golmahi.
      Introduction: management challenges of clinical laboratories are more complicated for educational hospital clinical laboratories. Managers can use tools of business intelligence (BI), such as information dashboards that provide the possibility of intelligent decision-making and problem solving about increasing income, reducing spending, utilization management and even improving quality. Critical phase of dashboard design is setting indicators and modeling causal relations between them. The paper describes the process of creating a map for laboratory dashboard. Methods: the study is one part of an action research that begins from 2012 by innovation initiative for implementing laboratory intelligent dashboard. Laboratories management problems were determined in educational hospitals by the brainstorming sessions. Then, with regard to the problems key performance indicators (KPIs) specified. Results: the map of indicators designed in form of three layered. They have a causal relationship so that issues measured in the subsequent layers affect issues measured in the prime layers. Conclusion: the proposed indicator map can be the base of performance monitoring. However, these indicators can be modified to improve during iterations of dashboard designing process.

      PubDate: Thu, 30 Jul 2015 07:00:06 GMT
  • Scientific Production of Medical Universities in the West of Iran: a
           Scientometric Analysis

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Masoud Rasolabadi, Shahnaz Khaledi, Fariba Khayati, Marya Maryam Kalhor, Susan Penjvini, Alireza Gharib.
      Introduction: This study aimed to compare scientific production by providing quantitative evaluation of science output in five Western Iranian Medical Universities including Hamedan, Ilam, Kermanshah, Kurdistan and Lorestan University of Medical Sciences using scientometrics indicators based on data indexed in Scopus for period between the years 2010 to 2014. Methods: In this scientometric study data were collected using Scopus database. Both searching and analyzing features of Scopus were used to data retrieval and analysis. We used Scientometrics indicators including number of publications, number of citations, nationalization index (NI), Internationalization Index (INI), H-index, average number of citations per paper, and growth index. Results: Five Western Iranian Universities produced over 3011 articles from 2010 to 2014. These articles were cited 7158 times with an average rate of 4.2 citations per article. H- Index of under study universities are varying from 14 to 30. Ilam University of Medical Sciences had the highest international collaboration with an INI of 0.33 compared to Hamedan and Kermanshah universities with INI of 0.20 and 0.16 respectively. The lowest international collaboration belonged to Lorestan University of Medical Sciences (0.07). The highest Growth Index belonged to Kurdistan University of Medical Sciences (69.7). Conclusion: Although scientific production of five Western Iranian Medical Universities was increasing, but this trend was not stable. To achieve better performance it is recommended that five Western Iranian Universities stabilize their budgeting and investment policies in research.

      PubDate: Thu, 30 Jul 2015 06:58:56 GMT
  • Family Medicine Education with Virtual Patients: a Qualitative Study

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Monika Sobocan, Zalika Klemenc-Ketis.
      Objectives: Virtual patients (VP) have been present within the medical education process for some time. Although they are assumed to be of great benefit for student learning, very little is know about student perception and outcomes of learning, especially during the pre-clerkship years. Therefore we have decided to investigate the use of VPs during lectures, which has never been analyzed before, but could present an opportunity for more effective and holistic learning. Methods: This was a qualitative study among the 4th year undergraduate medical students at the Medical Faculty, University of Maribor, Slovenia. Students, after completing 4 virtual patient cases during the semester, were asked to participate in focus groups. Using these focus groups we asked students to provide information about their perceptions of VP cases, their learning, and suggestions for educational improvements. Data was transcribed and analyzed using the grounded theory-based coding method (open coding). Results: Medical students reported having a positive attitude towards virtual patient learning. They perceived them as helpful for filling in knowledge gaps, learning appropriate patient care and clinical reasoning. However, especially within the setting of early clinical learning, students felt the need to discuss their questions with their tutors in order to achieve better learning outcomes. Conclusion: Students on teaching courses feel the need for structured instructor sessions and the integration of VPs in the course planning in order to maximize their learning outcomes.

      PubDate: Thu, 30 Jul 2015 06:57:10 GMT
  • Those Responsible for Approving Research Studies Have Poor Knowledge of
           Research Study Design: a Knowledge Assessment of Institutional Review
           Board Members

    • Abstract: 2015-08-03T23-18-06Z
      Source: Acta Informatica Medica
      Rahul Mhaskar, Elizabeth Barnett Pathak, Sarah Wieten, Thomas M. Guterbock, Ambuj Kumar, Benjamin Djulbegovic.
      Background: Institutional Review Board (IRB) members have a duty to protect the integrity of the research process, but little is known about their basic knowledge of clinical research study designs. Methods: A nationwide sample of IRB members from major US research universities completed a web-based questionnaire consisting of 11 questions focusing on basic knowledge about clinical research study designs. It included questions about randomized controlled trials (RCTs) and other observational research study designs. Potential predictors (age, gender, educational attainment, type of IRB, current IRB membership, years of IRB service, clinical research experience, and self-identification as a scientist) of incorrect answers were evaluated using multivariate logistic regression models. Results: 148 individuals from 36 universities participated. The majority of participants, 68.9% (102/148), were holding a medical or doctoral degree. Overall, only 26.5% (39/148) of participants achieved a perfect score of 11. On the six-question subset addressing RCTs, 46.6% (69/148) had a perfect score. Most individual questions, and the summary model of overall quiz score (perfect vs. not perfect), revealed no significant predictors – indicating that knowledge deficits were not limited to specific subgroups of IRB members. For the RCT knowledge score there was one significant predictor: compared with MDs, IRB members without a doctoral degree were three times as likely to answer at least one RCT question incorrectly (Odds Ratio: 3.00, 95% CI 1.10-8.20). However, even among MD IRB members, 34.1% (14/41) did not achieve a perfect score on the six RCT questions. Conclusions: This first nationwide study of IRB member knowledge about clinical research study designs found significant knowledge deficits. Knowledge deficits were not limited to laypersons or community advocate members of IRBs, as previously suggested. Akin to widespread ethical training requirements for clinical researchers, IRB members should undergo systematic training on clinical research designs.

      PubDate: Thu, 30 Jul 2015 06:53:12 GMT
  • In Memoriam on Assa Reichert (1943 - 2015)

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Tue, 26 May 2015 03:58:23 GMT
  • The Most Influential Scientists in the Development of Medical Informatics
           (6): Heinz Zemanek

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Izet Masic.

      PubDate: Tue, 26 May 2015 03:55:34 GMT
  • Dermatoglyphics and Reproductive Risk in a Family with Robertsonian
           Translocation 14q;21q

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Selim Kolgeci, Jehona Kolgeci, Mehmedali Azemi, Aferdita Daka, Ruke Shala-Beqiraj, Ilir Kurtishi, Mentor Sopjani.
      Aim: The present study is carried out to evaluate the risk of giving birth to children with Down syndrome in a family with Robertsonian translocation 14q;21q, and to find the dermatoglyphic changes present in carriers of this translocation. Methods: Cytogenetics diagnosis has been made according to Moorhead and Seabright method, while the analysis of prints (dermatoglyphics analysis) was made with the Cummins and Midlo method. Results: Cytogenetic diagnosis has been made in a couple who suffered the spontaneous miscarriages and children with Down syndrome. Robertsonian translocation between chromosomes 14 and 21 (45, XX, der (14; 21) (q10; q10)) was found in a female partner who had four pregnancies, in two of which was found fetus karyotype with trisomy in chromosome 21 and pregnancies were terminated. The outcome of fourth pregnancy was twin birth, one of them with normal karyotype and another with Down syndrome due to Robertsonian translocation inherited by mother side. Specific dermatoglyphics traits are found in the child carrying Down syndrome, whereas several traits of dermatoglyphics characteristic of Down syndrome have been displayed among the silent carriers of Robertsonian translocation 14q;21q. Conclusion: Robertsonian translocation found in female partner was the cause of spontaneous miscarriages, of giving birth to a child with Down syndrome, and of trisomy of chromosome 21 due to translocation in two pregnancies.

      PubDate: Tue, 26 May 2015 03:53:51 GMT
  • Successful Implantation of Bipolar Epicardial Leads and Dual Chamber
           Pacemaker in Infant After Postoperative Atrioventricular Heart Block

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Edin Omerbasic, Ilirijana Haxhibeqiri Karabdic, Elnur Tahirovic.
      Total atrioventricular (AV) block is inconvenient and serious complication of open heart surgery. Permanent total AV block requires the implantation of permanent pacemaker in order to allow normal hemodynamics and patient's survival. In infancy additional challenge is the surgical approach, the selection of electrodes and PM, as well as place of implantation. We are publishing case report of successful double-chamber DDD pacemaker implantation at an infant born with Fallot tetralogy and with low birth weight due to complete AV block after primary surgical correction of these congenital defects.

      PubDate: Tue, 26 May 2015 03:48:35 GMT
  • Information Retrieval in Telemedicine: a Comparative Study on
           Bibliographic Databases

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Maryam Ahmadi, Roghayeh Ershad Sarabi, Roohangiz Jamshidi Orak, Kambiz Bahaadinbeigy.
      Background and Aims: The first step in each systematic review is selection of the most valid database that can provide the highest number of relevant references. This study was carried out to determine the most suitable database for information retrieval in telemedicine field. Methods: Cinhal, PubMed, Web of Science and Scopus databases were searched for telemedicine matched with Education, cost benefit and patient satisfaction. After analysis of the obtained results, the accuracy coefficient, sensitivity, uniqueness and overlap of databases were calculated. Results: The studied databases differed in the number of retrieved articles. PubMed was identified as the most suitable database for retrieving information on the selected topics with the accuracy and sensitivity ratios of 50.7% and 61.4% respectively. The uniqueness percent of retrieved articles ranged from 38% for Pubmed to 3.0% for Cinhal. The highest overlap rate (18.6%) was found between PubMed and Web of Science. Less than 1% of articles have been indexed in all searched databases. Conclusion: PubMed is suggested as the most suitable database for starting search in telemedicine and after PubMed, Scopus and Web of Science can retrieve about 90% of the relevant articles.

      PubDate: Tue, 26 May 2015 03:46:59 GMT
  • Education and Training for Major Incidents Through Medical Response to
           Major Incidents–MRMI course

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Josip Samardzic, Boris Hreckovski, Ismar Hasukic.
      Incidence of major incidents nowadays is in constant growth, especially in last decade. Main goal of all health systems is to minimize and prevent tragic outcomes of major incidents, thus reducing morbidity and mortality and psychological and physical suffering. Lessons learned from Major Incidents throughout the World point out that tragical outcomes could be avoided through adequate preparation and planning. Necessity to plan and to educate to response to Major incident is greater than ever. Finally it is legal obligation that every hospital has plan in case of Major Incident. Effective planning must incorporate: identification of risks, methods of prevention, identification of all recourses, anticipation of errors and detailed protocol of response for each participant. Knowledge and skills needed for Major incident situations must be adopted through interactive training and practical exercise („learning by doing„). That can be achieved by field exercises and by simulation model. Simulation model has many advantages and enables simultaneous education and training of all participants; scene, transport, hospitals, communication and command which than can be evaluated through objective outcomes. The goal is to train medical staff in real time, on position they are assigned to, with available resources in conditions of Major incident.

      PubDate: Tue, 26 May 2015 03:45:42 GMT
  • Data Standards in Tele-radiology

    • Abstract: 2015-05-27T14-20-52Z
      Source: Acta Informatica Medica
      Mansoor Fatehi, Reza Safdari, Marjan Ghazisaeidi, Mohamad Jebraeily, Mahdi Habibi-koolaee.
      Data standards play an important role to provide interoperability among different system. As other applications of telemedicine, the tele-radiology needs these standards to work properly. In this article, we conducted a review to introduce some data standards about tele-radiology. By searching PUBMED and Google Scholar database, we find more relevant articles about data standards in tele-radiology. Three categories of standards identified, including data interchange, document and terminology standards. Data interchange standards, including those which facilitate the understanding of the format of a massage between systems, such as DICOM and HL7. Document standards, including those which facilitate the contents of a massage, such as DICOM SR and HL7 CDA. And terminology standards, including those which facilitate the understanding of concepts of the domain. Since, the harmonization between different standards are important to meet interoperability, so the more effort is needed to conduct harmonization between tele-radiology standards and other domain.

      PubDate: Tue, 26 May 2015 03:44:13 GMT
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