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Journal Cover Journal of Clinical Urology
  [SJR: 0.183]   [H-I: 5]   [18 followers]  Follow
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Print) 2051-4158 - ISSN (Online) 2051-4166
   Published by Sage Publications Homepage  [842 journals]
  • Editorial
    • Authors: Pearce; I.
      Pages: 140 - 140
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415816640990
      Issue No: Vol. 9, No. 3 (2016)
  • Clinical Research Toolkit for Urologists
    • Authors: Lamb, B. W; Rajan, P.
      Pages: 141 - 141
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415816632390
      Issue No: Vol. 9, No. 3 (2016)
  • Radiation therapy for urological cancers
    • Authors: Ahmad, S; Zakikhani, P, Gietzman, W, Macdonald, G, Royle, J.
      Pages: 142 - 150
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415816634564
      Issue No: Vol. 9, No. 3 (2016)
  • Erectile dysfunction following end-to-end urethroplasty in pelvic fracture
           urethral distraction defect patients
    • Authors: Patwardhan, S. K; Shelke, U. R, Ismail, A. M, Kaje, Y. D, Singh, A. G, Daga, S.
      Pages: 151 - 155
      Abstract: Objectives: The close relationship of the neuro-vascular bundle, cavernosal tissue of the penis and the bony pelvis results in high risk of concomitant injury associated with pelvis fractures, with resultant urethral defect and erectile dysfunction (ED). The present study aims to analyse and correlate the type of trauma, number of surgical interventions, urethral defect length and surgical steps performed during urethroplasty with erectile function. Method: This was an observational study. All patients with pelvis fracture urethral distraction defect (PFUDD) who required end-to-end urethroplasty (E-E urethroplasty) from August 2010 to July 2014 were included. Results: Thirty-four per cent had defect length of 0.5–2 cm, 50% had defect length of 2.1–4 cm. Of 32, 34% required re-intervention. Inferior pubectomy was required in 36% in the 0.5–2 cm group and in 94% in the 2.1–4 cm group. On follow-up, 22% of patients had neurogenic ED, and 63% had vascular ED, of whom 44% had arterial, 3% had venous, and 16% had mixed aetiology. Patients with neurogenic aetiology had shorter urethral defect and 43% needed inferior pubectomy. Patients with vascular aetiology had longer urethral defect, 90% required inferior pubectomy. Conclusions: ED is related to the length of urethral defect, and operative manoeuvers performed during E-E urethroplasty.
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415815606855
      Issue No: Vol. 9, No. 3 (2016)
  • Acute cholecystitis after urological surgery: A report of 11 cases in our
           department and a review of the literature
    • Authors: Yokoyama, H; Hara, H, Ogawa, T, Ishizuka, O.
      Pages: 156 - 161
      Abstract: Objective: Postoperative acute cholecystitis (PAC) after gastrointestinal surgery is considered to be a relatively common complication. However, PAC after urological surgery is extremely rare. Patients and methods: We conducted a retrospective review of 2583 patients who underwent urological surgery in our department from 2006 to 2014 to identify those who developed acute cholecystitis in the postoperative period. Results: Of the 2583 patients, 11 (0.4%) were diagnosed with PAC. The study population consisted of 10 (91%) men and one (9%) woman. Among them, five (45%) patients had acalculous cholecystitis. The median interval between the preceding urological surgery and the onset of PAC was 16 days (range, 3–39 days). Emergent cholecystectomy and/or gallbladder drainage was performed in eight (73%) cases. Although four (36%) patients developed septic shock and were treated in the intensive care unit, cholecystitis improved in all cases. One patient died of her underlying disease (adrenal cancer) two months after PAC. Conclusion: Most routinely performed urological surgeries can cause PAC. The symptoms of PAC may be masked in the postoperative period. Urologists must be aware of PAC and should not hesitate to perform further inspection and consultation with a gastroenterologist in cases in which it is suspected.
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415815603600
      Issue No: Vol. 9, No. 3 (2016)
  • Post-operative use of Low Molecular Weight Heparin: Are patients doing
           their bit?
    • Authors: Hardy, T; Upchurch, E, Duff, H, Davenport, K.
      Pages: 162 - 165
      Abstract: Introduction: Current National Institute for Health and Care Excellence (NICE) guidelines recommend the use of Low Molecular Weight Heparin (LMWH) for one month post-operatively in abdominal and pelvic cancer surgery to reduce risk of venous thromboembolism. We audited the prescription of LMWH at discharge and the compliance of patients with LMWH post-operatively and instigated measures to improve compliance. Materials and Methods: All patients undergoing major urological surgery from November 2011 to April 2012 were audited, with data collected on evidence of post-operative prescription (from discharge summaries). Patients within this 3-month period were questioned regarding compliance following discharge. Following this, changes were instigated to improve compliance (earlier discussion of post-operative LMWH administration in clinic, improved patient and junior doctor education). All patients undergoing surgery from November 2012 to June 2013 were identified and a re-audit completed. Results: Post-operative prescription of LMWH improved overall from 73% to 88%. Patient compliance to complete LMWH course improved from 23% to 88%. At re-audit, 97% of patients felt that training was adequate, and 94% of patients understood the rationale for taking LMWH at re-audit. Conclusion: Education of junior doctors improved prescription of LMWH at discharge. Improved patient education improves community LMWH use compliance post-discharge.
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415815606847
      Issue No: Vol. 9, No. 3 (2016)
  • The outcome of intravesical onabotulinum toxin injections for salvage
           therapy of refractory detrusor overactivity following augmentation
    • Authors: Mishra, V; Pakzad, M, Hamid, R, Shah, P. J. R, Ockrim, J. L, Greenwell, T. J.
      Pages: 166 - 169
      Abstract: Objective: The objective of this article is to assess the effect of intravesical onabotulinum toxin A (OBTX-A) injections in patients with persistent/refractory symptomatic detrusor overactivity (DO) and urge urinary incontinence (UUI) following previous augmentation enterocystoplasty. Patients and methods: We conducted a retrospective review of all patients with previous augmentation enterocystoplasty having intravesical OBTX-A for persistent/refractory DO and UUI. Information on demographics, original diagnosis, date and technique of enterocystoplasty, dose of OBTX-A and symptomatic outcomes was recorded. Results: Fifteen patients (three men) with mean age 42 years were studied. Eight out of 15 (53%) reported complete continence or significant improvement, while the remaining seven (47%) noticed no difference in their symptoms. Urodynamics were repeated in these seven patients and persistent DO was confirmed. Four out of five (80%) NDO patients who received 300 U of OBTX-A reported a favourable outcome, whereas a favourable response was noted in only four out of 10 IDO (40%) when smaller amounts of OBTX-A (100 U or 200 U) were used. Conclusions: Intravesical OBTX-A injections completely resolved or significantly improved persistent/recurrent symptoms of DO in 53% of patients with a previous augmentation enterocystoplasty. The success rate was higher for those receiving the higher dose of 300 U and/or those with NDO.
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415815605017
      Issue No: Vol. 9, No. 3 (2016)
  • Incidental prostate cancer diagnosed following a transurethral resection
           of the prostate: A national database analysis in England
    • Authors: Anastasiadis, E; van der Meulen, J, Emberton, M.
      Pages: 170 - 176
      Abstract: Objectives: The aim was to compare prostate cancer and all-cause mortality in patients diagnosed with prostate cancer following a transurethral resection of the prostate (TURP) (incidental prostate cancer, IPC), to men diagnosed with localised non-incidental prostate cancer (NIPC). Patients and methods: Men diagnosed with localised prostate cancer between 2000 and 2008 were identified from the English national cancer registry. Their records were linked to the Hospital Episode Statistics (HES) database of hospital admissions in England to identify men who had a TURP. Men were considered to have IPC if prostate cancer was diagnosed less than 60 days after TURP. Mortality rates were calculated using the Kaplan–Meier method. Mortality rate ratios (RR) comparing IPC and NIPC were calculated with multivariable Poisson regression adjusting for age group, co-morbidities, year of diagnosis and radical treatment. Results: A total of 192,960 men were included. Of these, 6666 (3.5%) had IPC and 186,294 (96.5%) NIPC. Median follow-up was 4.7 years (0.5–11.0). Ten-year prostate cancer mortality was 17.1% in IPC, 19.0% in NIPC. With adjustment, the prostate cancer-specific mortality in IPC was 30% lower than NIPC (RR 0.70, 95% CI 0.65–0.75, p
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415815603275
      Issue No: Vol. 9, No. 3 (2016)
  • The place of antifungal treatment in interstitial cystitis
    • Authors: Murshidi; M. S.
      Pages: 177 - 179
      Abstract: Background and objectives: Initial study to treat interstitial cystitis with anti-fungal treatment. Methods and results: This is an initial report about anti-fungal treatment in three patients with interstitial cystitis. All patients had been diagnosed and receiving treatment for at least two years. Various modalities had led only to minimal improvement. Anti-fungal therapy in the form of fluconazole was commenced in these patients. There was significant response in two cases; the third one had a moderate response. Conclusion: Anti-fungal treatment may play a role in the treatment of interstitial cystitis; further elaborate studies are needed. Research is also needed to study the role of fungal infection in the pathogenesis of interstitial cystitis.
      PubDate: 2016-04-20T03:29:05-07:00
      DOI: 10.1177/2051415815608578
      Issue No: Vol. 9, No. 3 (2016)
  • Influence of different doses of trospium and solifenacin on manageability
           of OAB symptoms with different severity in elderly men and women
    • Authors: Kosilov, K. V; Loparev, S. A, Ivanovskaya, M. A, Kosilova, L. V.
      Pages: 180 - 188
      Abstract: Objective: We studied the rationale for using standard and increased dosages of solifenacin and trospium against overactive bladder (OAB) symptoms of different severity among elderly patients. Methods: A total of 327 patients took part in the study: 199 women and 128 men older than 65 years (median age 69.1). The state of the lower urinary tracts was estimated by cystometry, ICIQ-SF and bladder diaries. Frequency of urgency urinary incontinence (UUI) was taken as a criterion of OAB symptom severity. Result: Administration of double-dosed trospium and solifenacin leads to decrease of frequency of UUI both in the group with severe symptoms (B1: 6.1 (0.5) ->2.4 (0.9), p 0.5 (0.4), p 0.9 (0.5), p 4.3 (1.5), p >= 0.05). During the experiment six patients (1.8%) elected not to participate because of intolerable adverse events. Forty-seven more individuals (14.4%) felt adverse effects, among which the most frequent were: xerostomia (15 patients or 4.6%), faintness (nine patients or 3.8%), dryness of integuments (six patients or 1.8%). Conclusion: A standard-dose combination of solifenacin and trospium in older patients with moderate symptoms of OAB enables a good therapeutic effect in a short time without increasing risk of side effects. High therapeutic doses of antimuscarinic drugs are reasonable for older men and women with severe symptoms of OAB. Increasing the dose of simultaneous use of solifenacin and trospium yields a good therapeutic effect to correct UUI; however, it raises the hazard of appearance of adverse effects. The number of side effects in the group of elderly individuals who were taking the combination of increased and standard dosages of solifenacin and trospium does not significantly differ.
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415815600970
      Issue No: Vol. 9, No. 3 (2016)
  • Teaching of intermittent self-catheterisation through dedicated nurse-led
           TOV clinic for patients with uncomplicated acute urinary retention: How
           useful is it in practice?
    • Authors: Bekarma, H; Rooney, H, Khan, R, Miller, G, Dunn, I.
      Pages: 189 - 192
      Abstract: Objectives: Acute urinary retention (AUR) is a common urological emergency. Our institution has established an outpatient pathway for managing patients with uncomplicated AUR on discharge from A&E: with catheter education and alpha-blocker therapy. They are followed up in a nurse-led clinic where intermittent self-catheterisation (ISC) can be taught if required. The aim of this study is to investigate the outcomes of our nurse-led trial of void (TOV) clinic and specifically the merit of teaching ISC. Methods: Data was prospectively collected and analysed for all patients with AUR who were followed up in the nurse-led TOV clinic between October 2012 and December 2014. Results: Over 26 months, 120 men with AUR attended the TOV clinic with an average age of 71 years (range 28–94 years). Forty-nine of 120 (41%) patients had an identifiable cause for AUR (UTI=13, constipation=13, alcohol=11, anti-cholinergics=7, post-operative=4 and post-brachytherapy=1). Sixty-four men passed and 50 failed TOV. Six were excluded from this analysis as they did not proceed to TOV in clinic (three requested LTC and three were not appropriate for outpatient clinic). All 50 patients who failed TOV were offered ISC. Thirty-two of 50 patients (64%) learnt ISC. Ten declined and eight were unable to perform ISC. Only seven of 50 patients (14%) went on to have a TURP, four of whom had declined to learn ISC. Of the remaining 43 patients, 24 (56%) had return of spontaneous voiding. Conclusion: In our experience, a pathway for reviewing AUR patients in a nurse-led TOV clinic where expertise for ISC tuition is available is extremely useful. In our series, only 14% of patients who failed TOV required TURP. Bladder function often returns to normal over time but ISC offers patients an autonomous management option if satisfactory to themselves whilst avoiding the complications of LTC.
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415815603602
      Issue No: Vol. 9, No. 3 (2016)
  • Medullary sponge kidney: A treatment conundrum
    • Authors: Kass-Iliyya, A; Young, J. G.
      Pages: 193 - 200
      Abstract: Medullary sponge kidney (MSK) is a congenital kidney malformation that is characterized by dilatation of the collecting tubules in the medullary pyramids. Cyst-like areas then form which predispose to nephrocalcinosis, stone formation and recurrent urinary tract infection (UTI). There is an association with defective distal renal tubular acidification and concentration abnormalities such as hypocitraturia. MSK is generally believed to be a sporadic disorder, but an autosomal dominant inheritance is also reported. More recently genetic mutations have been recognised as a possible contributor to the aetiology of the condition. In this article we summarize the available English language literature on the subject of MSK, including its pathogenesis, diagnosis, prognosis and treatment.
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415816632075
      Issue No: Vol. 9, No. 3 (2016)
  • Applying for research funding. Part 1 - sources of funding.
    • Authors: Nelson, A. W; Gnanapragasam, V. J.
      Pages: 201 - 204
      Abstract: Objective: In this article we summarise sources of research funding, principally for individuals seeking to undertake research for a higher degree at the beginning of their research careers. Features of individual funding schemes are highlighted, along with an overview of the process of applying for research funding. It is intended that this article should be a useful resource for those entering research careers. Conclusion: Funding available from the Medical Research Council, Wellcome Trust, National Institute for Health Research, Royal College of Surgeons of England, Royal College of Surgeons of Edinburgh and The Urology Foundation is summarised.
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415815626322
      Issue No: Vol. 9, No. 3 (2016)
  • Unexpected outcome after partial epididymectomy for chronic testicular
    • Authors: Nandwani, G. M; Elmasry, Y, Dabbagh, V, Chaplin, B. J.
      Pages: 205 - 207
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415814536386
      Issue No: Vol. 9, No. 3 (2016)
  • Bucking the trend with buccal mucosa: long-term durability of substitution
           buccal mucosa graft ureteroplasty in the management of a difficult
           anastomotic stricture following trans-ureteroureterostomy
    • Authors: Rudd, I. D; Nair, R, Anderson, C. J.
      Pages: 208 - 210
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415814532639
      Issue No: Vol. 9, No. 3 (2016)
  • Journal of Clinical Urology - Abbreviated Manuscript Submission Guidelines
    • Pages: 211 - 212
      PubDate: 2016-04-20T03:29:06-07:00
      DOI: 10.1177/2051415816630893
      Issue No: Vol. 9, No. 3 (2016)
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