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JRSM Cardiovascular Disease

Open Access journal
ISSN (Online) 2048-0040
Published by Sage Publications

[676 journals]

Thrombolysis of an acute stroke presentation with an incidental unruptured aneurysm
- Authors: Ganesalingam, J; Redwood, R, Jenkins, I.
  Pages: 1 - 1
  Abstract: Many patients with acute ischaemic stroke have contraindications to thrombolytic therapy. We describe a 45 yr old Afro-Caribbean female with HbSC disease whom was electively admitted for a cerebral angiogram to evaluate an intracavernous aneurysm measuring 20 mm in diameter. During the procedure, she suffered a right MCA territory ischaemic event with a NIHSS of 10. A CT angiogram demonstrated no dissection and no evidence of a major vessel occlusion. Tissue plasminogen activator (tPA) was administered intravenously within 60 minutes of symptom onset. She had clinical and haematological evidence of a painful sickle cell crisis and required manual exchange transfusion within a few hours of thrombolysis. This is the first reported case of the use of thrombolysis for acute stroke in a sickle cell crisis; and in the presence of such a large unruptured aneurysm. A registry of unusual thrombolysis cases might help clinicians in cases when there is little evidence to support decision-making.
  Keywords: Elder abuse
  PubDate: 2012-03-01T00:00:00-08:00
  DOI: 10.1177/2048004013478808|hwp:resource-id:rsmcardio;2/1/1
  Issue No: Vol. 2, No. 1 (2012)