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Journal Cover Journal of Clinical and Experimental Hepatology
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   ISSN (Print) 0973-6883
   Published by Elsevier Homepage  [2970 journals]
  • Can Testing the Impact of Minimal Hepatic Encephalopathy on Driving Skills
           be Prolific to Translate Research to Real Life Clinical Medicine'
    • Authors: Sunil Taneja; Radha K. Dhiman
      Pages: 1 - 2
      Abstract: Minimal hepatic encephalopathy (HE) is considered a continuum of spectrum of HE. As the liver disease progresses, the abnormalities in central nervous function with impairment in attention, psychomotor speed, visuo-spatial perception and delayed information processing start disquieting the patient without any obvious clinical signs of HE. This cognitive impairment is so subtle to be picked up by the routine neurological clinical examination and requires specialized tests for diagnosis, hence unless specifically looked for will be missed in the outpatient clinic.
      Citation: Journal of Clinical and Experimental Hepatology 6, 1 (2016)
      PubDate: 2016-03
      DOI: 10.1016/j.jceh.2016.03.007
      Issue No: Vol. 6, No. 1 (2016)
       
  • Advances in Management of Hepatocellular Carcinoma
    • Authors: Soumya Jagannath; Shalimar
      Pages: 68 - 70
      Abstract: Gastroenterology 2016;150:488–498.
      Citation: Journal of Clinical and Experimental Hepatology 6, 1 (2016)
      PubDate: 2016-03
      DOI: 10.1016/j.jceh.2016.03.006
      Issue No: Vol. 6, No. 1 (2016)
       
  • Hepatobiliary Quiz—17 (2016)
    • Authors: Sahaj Rathi; Radha K. Dhiman
      Pages: 71 - 72
      Citation: Journal of Clinical and Experimental Hepatology 6, 1 (2016)
      PubDate: 2016-03
      DOI: 10.1016/j.jceh.2016.03.004
      Issue No: Vol. 6, No. 1 (2016)
       
  • Hepatobiliary Quiz Answers—17 (2016)
    • Authors: Sahaj Rathi; Radha K. Dhiman
      Pages: 73 - 76
      Abstract: Hepatorenal syndrome (HRS) represents a life-threatening form of renal failure in patients with decompensated cirrhosis. It occurs in 18% of patients with decompensated cirrhosis annually.1 Terlipressin, along with volume expansion-using albumin, is one of the most effective forms of therapy, leading to a reversal in about a third of cases. Baseline serum creatinine is the strongest predictor of reversal of HRS. Patients with serum creatinine
      Citation: Journal of Clinical and Experimental Hepatology 6, 1 (2016)
      PubDate: 2016-03
      DOI: 10.1016/j.jceh.2016.03.005
      Issue No: Vol. 6, No. 1 (2016)
       
  • Hepatocyte Regeneration and Inhibition of Proliferation: Two Sides of a
           Coin
    • Authors: Soumya J. Mahapatra; Shalimar
      Abstract: J Hepatol (2016), http://dx.doi.org/10.1016/j.jhep.2016.02.040
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-06-15
      DOI: 10.1016/j.jceh.2016.06.001
       
  • Enucleation Sign: A Computed Tomographic Appearance of Ruptured
           Hepatocellular Carcinoma
    • Authors: Manphool Singhal; Upasna Sinha, Naveen Kalra, Ajay Duseja, Niranjan Khandelwal
      Abstract: Rupture of hepatocellular carcinoma (HCC) is a catastrophic complication, which carries high mortality. We report a case of spontaneous rupture of HCC, diagnosis of which was considered on clinical presentation and confirmed on computed tomographic (CT) scan. On CT scan, characteristic ‘enucleation sign’ was observed on arterial phase imaging, where a hypervascular peripheral mass showing central necrosis was seen protruding from liver surface with discontinuity of hepatic parenchyma associated with high attenuation ascites.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-06-06
      DOI: 10.1016/j.jceh.2016.05.004
       
  • Progressive Familial Intrahepatic Cholestasis (PFIC) in Indian Children:
           Clinical Spectrum and Outcome
    • Authors: Sajan Agarwal; Bikrant Bihari Lal, Dinesh Rawat, Archana Rastogi, Kishore G.S. Bharathy, Seema Alam
      Abstract: To study the clinical and laboratory profile of children with progressive familial intrahepatic cholestasis (PFIC) and evaluate their outcome.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-06-04
      DOI: 10.1016/j.jceh.2016.05.003
       
  • The Mystique of Brain Death
    • Authors: Padmashri Rastogi
      Abstract: “No one wants to die. Even people who want to go to heaven don’t want to die to go there. And yet death is the destination we all share. No one has ever escaped it. And that is as it should be, because Death is very likely the single best invention of life.”1 “Those who have the strength and the love to sit with the dying patient in the silence that goes beyond words will know that this moment is neither frightening nor painful but a peaceful cessation of the functioning of the body.”2 “If you don’t know how to die, don’t worry.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-06-03
      DOI: 10.1016/j.jceh.2016.05.007
       
  • Anti-HBc Screening of Blood Donors in Bangladesh: Relevance to Containment
           of HBV Propagation
    • Authors: Munira Jahan; Md Asadul Islam, Sheikh Mohammad Fazle Akbar, Kazuaki Takahashi, Shahina Tabassum, Atiar Rahman, Md Atiqul Haque, Joly Biswas, Shunji Mishiro, Mamun Al-Mahtab
      Abstract: To avoid further transmission of hepatitis B virus (HBV) infection, blood is tested for hepatitis B surface antigen (HBsAg) before transfusion. However, post-transfusion hepatitis B has been detected in clinics after transfusion of HBsAg-negative blood. The study presented here was undertaken to assess if HBsAg-negative blood is free from HBV or not.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-06-02
      DOI: 10.1016/j.jceh.2016.05.002
       
  • Iatrogenic Cushing Syndrome from Interaction Between Ritonavir and Oral
           Budesonide During Direct Acting Antiviral Hepatitis C Therapy
    • Authors: Sern Wei Yeoh
      Abstract: Direct acting antiviral (DAA) regimens containing ritonavir have been developed to treat hepatitis C, with fewer side effects than that by interferon-based regimens. However prescribers must be aware of drug–drug interactions. There are multiple reports of iatrogenic Cushing syndrome (CS) caused by ritonavir, when used to treat human immunodeficiency virus, increasing the bioavailability of exogenous steroids by inhibiting cytochrome p450 enzymes in the liver and gut wall and thus reducing steroid metabolism.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-05-31
      DOI: 10.1016/j.jceh.2016.05.006
       
  • Hepatocellular Carcinoma Presenting as Dyspnea at Rest due to Innumerable
           Lung Metastasis
    • Authors: Naveen Kumar; Narendra Singh Choudhary, Neeraj Saraf, Sanjiv Saigal
      Abstract: Hepatocellular carcinoma (HCC) the most common primary tumor of the liver usually develops in the setting of chronic liver disease. The presentation is usually due to worsening of chronic liver disease or being detected incidentally on imaging. Rarely metastasis to distant organ becomes the presentation. The authors describe a case of a 70-year-old woman who presented with dyspnea of 2 weeks duration. She was diagnosed as having HCC and extensive multiple pulmonary metastases. She was symptomatic only for the pulmonary metastasis with only 2 lesions in the liver.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-05-31
      DOI: 10.1016/j.jceh.2016.05.005
       
  • Non-invasive Diagnosis of Oesophageal Varices Using Systemic Haemodynamic
           Measurements by Finometry: Comparison with Other Non-invasive Predictive
           Scores
    • Authors: Kara Rye; Gerri Mortimore, Andrew Austin, Jan Freeman
      Abstract: Cirrhosis and portal hypertension are characterised by a hyperdynamic circulation, which is independently associated with variceal size. Non-invasive techniques for measurement of systemic haemodynamics are now available.The aim of the study was to prospectively assess the accuracy of systemic haemodynamics measured non-invasively for the detection of oesophageal varices in cirrhotic patients as compared to other currently available non-invasive methods.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-05-20
      DOI: 10.1016/j.jceh.2016.05.001
       
  • Why are we Poor Organ Donors: A Survey Focusing on Attitudes of the Lay
           Public From Northern India
    • Authors: Rajesh Panwar; Sujoy Pal, Nihar R. Dash, Peush Sahni, Aarti Vij, Mahesh C. Misra
      Abstract: Knowledge, sociocultural views, and awareness about organ donation in the general population are important for the success of deceased organ donation. There is an urgent need to gather this information in order to find out the reasons for poor organ donation rates in India.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-05-09
      DOI: 10.1016/j.jceh.2016.04.001
       
  • Urinary Metabotyping of Hepatocellular Carcinoma in a UK Cohort Using
           Proton Nuclear Magnetic Resonance Spectroscopy
    • Authors: Mohamed I.F. Shariff; Jin U. Kim, Nimzing G. Ladep, Mary M.E. Crossey, Larry K. Koomson, Abigail Zabron, Helen Reeves, Matthew Cramp, Stephen Ryder, Shaun Greer, I. Jane Cox, Roger Williams, Elaine Holmes, Kathryn Nash, Simon D. Taylor-Robinson
      Abstract: Discriminatory metabolic profiles have been described in urinary 1H nuclear magnetic resonance (NMR) spectroscopy studies of African patients with hepatocellular carcinoma (HCC). This study aimed to assess similarities in a UK cohort, where there is a greater etiological diversity.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-04-27
      DOI: 10.1016/j.jceh.2016.03.003
       
  • A Rare Congenital Disorder of Intrahepatic Bile Ducts
    • Authors: Krishnasamy Narayanasamy; Jaiganesh Mohan, Kumagurubaran Sivanesan, Shifa Babu, Prem Kumar, Karthick Rajendran
      Abstract: A 34-year-old male presented with chief complaints of jaundice for last 4 weeks and abdominal distension and swelling of the legs for 3 weeks. There was no associated abdominal pain, pale stools, or itching. He is a known diabetic on insulin therapy, and occasionally consumes alcohol. There was no family history of any liver-related diseases. His initial workup showed hemoglobin of 8.8g%, total counts of 9800cells/cumm, and platelets counts of 58000cells/cumm. Liver function tests showed total bilirubin of 13.5, direct bilirubin of 10.4, alanine transaminase of 1560IU/L (normal 8
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-31
      DOI: 10.1016/j.jceh.2016.02.004
       
  • Limited Fibrosis Progression but Significant Mortality in Patients
           Ineligible for Interferon-Based Hepatitis C Therapy
    • Authors: Manhal Izzy; Ghalib Jibara, Aws Aljanabi, Mustafa Alani, Emily Giannattasio, Hina Zaidi, Zaid Said, Paul Gaglio, Allan Wolkoff, John F. Reinus
      Abstract: Individuals ineligible for interferon-based hepatitis C therapy may have a worse prognosis than patients who have failed or not received treatment.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-25
      DOI: 10.1016/j.jceh.2016.02.006
       
  • Long-Term Outcomes of Liver Transplantation for Hepatic Sarcoidosis: A
           Single Center Experience
    • Authors: Muhammad Bilal; Sanjaya K. Satapathy, Mohammad K. Ismail, Jason M. Vanatta
      Abstract: Hepatic sarcoidosis is a rare indication for orthotopic liver transplantation (OLT). Hence, studies evaluating these patients are scarce. We present a single center experience with OLT for hepatic sarcoidosis in a case–control study.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-21
      DOI: 10.1016/j.jceh.2016.02.005
       
  • Honeycomb Cyst of the Liver
    • Authors: Sunil Taneja; Pramod Kumar, Ajay Duseja, Virendra Singh, Radha K. Dhiman, Yogesh Chawla
      Abstract: A 34-year-old female presented with pain in the abdomen for 5 months. The general physical and systemic examination was normal. Ultrasound of abdomen showed two well-defined exophytic multiloculated cystic lesion of size 8.4cm×7cm and 5cm×3.2cm in segment 2/4 and 8 of the liver. Radial endoscopic ultrasound was done to confirm the diagnosis of hydatid cyst, which showed two anechoic multiseptated honeycomb-shaped cysts in liver with daughter cysts and hydatid sand (Figure 1). Later the serology for IgG antibody for hydatidosis came positive in 1:1600 titres.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-19
      DOI: 10.1016/j.jceh.2016.03.001
       
  • Giant-cell Hepatitis—Rare Entity in Adults
    • Authors: Shiran Shetty; Krishnaveni Janarthanan, Venkatakrishnan Leelakrishnan, Vadakkepat Nirmala
      Abstract: Giant-cell hepatitis (GCH) is characterized by parenchymal inflammation with formation of large multinucleated hepatocytes in response to a variety of insults to the liver. Although it is commonly described in neonates, it rarely occurs in adults. Here we report a case of GCH because of herbal medicine intake.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-16
      DOI: 10.1016/j.jceh.2016.02.007
       
  • Unusual Cause of Cholestatic Jaundice in a Young Immunocompetent Male
    • Authors: Puneet Chhabra; Surinder S. Rana, Deepak Gunjan, Vishal Sharma, Pranab Dey, Deepak K. Bhasin
      Abstract: A 18-year-old boy with no previous comorbidities presented with jaundice, fever, and loss of weight and appetite of one-month duration. He had no previous history of long-standing fatigue, jaundice, ascites, upper gastrointestinal bleeding, or encephalopathy. Based on chest skiagram findings of nonhomogenous opacities in right upper lobe (Figure 1; arrow), he was started on antitubercular therapy (ATT) in an outside medical facility. Following this, he had worsening of jaundice and four weeks later developed progressively increasing abdominal distension.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-15
      DOI: 10.1016/j.jceh.2016.03.002
       
  • Coffee and Liver Disease
    • Authors: Manav Wadhawan; Anil C. Anand
      Abstract: Coffee is the most popular beverage in the world. Consumption of coffee has been shown to benefit health in general, and liver health in particular. This article reviews the effects of coffee intake on development and progression of liver disease due to various causes. We also describe the putative mechanisms by which coffee exerts the protective effect. The clinical evidence of benefit of coffee consumption in Hepatitis B and C, as well as nonalcoholic fatty liver disease and alcoholic liver disease, has also been presented.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-08
      DOI: 10.1016/j.jceh.2016.02.003
       
  • Liver Transplantation for Alcohol-Related Liver Disease
    • Authors: Narendra S. Choudhary; Naveen Kumar, Sanjiv Saigal, Rahul Rai, Neeraj Saraf, Arvinder S. Soin
      Abstract: Alcoholic liver disease (ALD) is a common indication for liver transplantation. It is a much debated indication for deceased donor liver transplantation due to organ shortage and potential of alcohol relapse after liver transplantation. A six-month abstinence before liver transplantation is required at most centers to decrease chances of alcohol relapse after liver transplantation. However, this rule is not relevant for patients with severe alcoholic hepatitis or severely decompensated patients who are unlikely to survive till 6 months.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-07
      DOI: 10.1016/j.jceh.2016.02.001
       
  • Delayed Severe Hemobilia Due to Bilio-venous Fistula After Percutaneous
           Transhepatic Biliary Drainage: Treatment With Covered Stent Placement
    • Authors: Kumble S. Madhusudhan; Nihar R. Dash, Adil Afsan, Shivanand Gamanagatti, Deep N. Srivastava, Arun K. Gupta
      Abstract: Biliovenous fistula occurs due to development of a communication between hepatic duct and portal vein branches and is a rare complication of percutaneous transhepatic biliary drainage (PTBD). Most of them are self-limiting and only occasionally they need interventional management. Placement of biliary stent graft is a viable option. We present here a case of a 56-year-old male with carcinoma of gall bladder presenting with hemodynamic shock due to severe hemobilia after PTBD and treated successfully by biliary covered stent placement.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-03-04
      DOI: 10.1016/j.jceh.2016.02.002
       
  • Addition of Dexamethasone Alters the Bile Acid Composition by Inducing
           CYP8B1 in Primary Cultures of Human Hepatocytes
    • Abstract: Primary human hepatocytes offer the best human in vitro model for studies on human liver cell metabolism. Investigators use a variety of different media supplements and matrix biocoatings and the type of culture system used may influence the outcome.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-02-22
      DOI: 10.1016/j.jceh.2016.01.007
       
  • Acute Liver Failure Caused by Hepatitis A Virus with Dengue Coinfection
    • Authors: Sunil Taneja; Amritangsu Borakokty, Ajay Duseja, Radha Krishan Dhiman, Yogesh Chawla
      Abstract: Hepatitis A (HAV) infection and dengue fever are endemic in developing countries and are associated with increased morbidity and mortality. Both the infections are commonly seen during the rainy season and are associated with poor sanitation and low socioeconomic status.1 Due to diverse presentation, their coexistence can present a diagnostic dilemma and at times a difficult clinical scenario to manage due to the complicated course of the illness.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-02-10
      DOI: 10.1016/j.jceh.2016.01.006
       
  • Hemodynamic Response to Carvedilol is Maintained for Long Periods and
           Leads to Better Clinical Outcome in Cirrhosis: A Prospective Study
    • Authors: Vijendra Kirnake; Anil Arora, Varun Gupta, Praveen Sharma, Vikas Singla, Naresh Bansal, Mohan Goyal, Romesh Chawlani, Ashish Kumar
      Abstract: Non-selective beta-blockers (NSBBs), e.g. propranolol, are recommended for prophylaxis of variceal bleeding in cirrhosis. Carvedilol, a newer NSBB with additional anti-α1-adrenergic activity, is superior to propranolol in reducing portal pressure. Repeated HVPG measurements are required to identify responders to NSBB. We aimed to determine whether a single-time HVPG measurement, using acute-hemodynamic-response-testing, is sufficient to predict long-term response to carvedilol, and whether these responders have better clinical outcome.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-02-06
      DOI: 10.1016/j.jceh.2016.01.004
       
  • Dengue Virus Transmission from Living Donor to Recipient in Liver
           Transplantation: A Case Report
    • Authors: Raman K. Gupta; Gaurav Gupta, Vishal K. Chorasiya, Pradyut Bag, Rajeev Shandil, Vikram Bhatia, Manav Wadhawan, Vivek Vij, Ajay Kumar
      Abstract: Many infections are transmitted from a donor to a recipient through organ transplantations. The transmission of dengue virus from a donor to a recipient in liver transplantation is a rare entity, and currently, there is no recommendation for screening this virus prior to transplantation. We report a case of transmission of dengue virus from donor to recipient after liver transplantation. The recipient had a history of multiple admissions for hepatic encephalopathy and ascites. He was admitted in the ICU for 15 days for chronic liver disease, ascites, and acute kidney injury before transplantation.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-02-04
      DOI: 10.1016/j.jceh.2016.01.005
       
  • Innovative Approach of Using Esophageal Stent for Refractory Post-Band
           Ligation Esophageal Ulcer Bleed Following Living Donor Liver
           Transplantation
    • Authors: Narendra S. Choudhary; Rajesh Puri, Sanjiv Saigal, Neeraj Saraf, Randhir Sud, Arvinder S. Soin
      Abstract: Bleeding from post-banding esophageal ulcers is uncommon. It is associated with significant morbidity and mortality. The bleeding from post-banding ulcers is difficult to manage and may be refractory to endotherapy and pharmacological treatment; transjugular intrahepatic portosystemic shunt can be used in such cases. We present a case of refractory post-banding ulcer bleed in a liver transplant recipient, which was managed by placement of removable esophageal metal stent.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-01-29
      DOI: 10.1016/j.jceh.2016.01.003
       
  • Silibinin Inhibits Proliferation and Migration of Human Hepatic Stellate
           LX-2 Cells
    • Authors: Devaraj Ezhilarasan; Jonathan Evraerts, Sid Brice, Pedro Buc-Calderon, Sivanesan Karthikeyan, Etienne Sokal, Mustapha Najimi
      Abstract: Proliferation of hepatic stellate cells (HSCs) play pivotal role in the progression of hepatic fibrosis consequent to chronic liver injury. Silibinin (SBN), a flavonoid compound, has shown to possess cell cycle arresting potential against many actively proliferating cancers cell lines. The objective of this study was to evaluate the anti-proliferative and cell cycle arresting properties of SBN in rapidly proliferating human hepatic stellate LX-2 cell line.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-01-29
      DOI: 10.1016/j.jceh.2016.01.002
       
  • A Rare Presentation of Leishmaniasis
    • Authors: Ritesh Prajapati; Ashish Kumar, Praveen Sharma, Vikas Singla, Naresh Bansal, Shashi Dhawan, Anil Arora
      Abstract: Leishmaniasis or kala-azar is a protozoan disease that can present as cutaneous, mucocutaneous, visceral, and disseminated disease. In India, it is usually localized in distinct areas of Bihar, Jharkhand, West Bengal, and parts of Eastern Uttar Pradesh. Visceral leishmaniasis (VL) involves the visceral organs, mainly the liver, the spleen and bone marrow. VL is characterized by prolonged fever, massive splenomegaly, weight loss, progressive anemia, pancytopenia, and hypergammaglobulinemia, and can be complicated by serious infections.
      Citation: Journal of Clinical and Experimental Hepatology (2016)
      PubDate: 2016-01-23
      DOI: 10.1016/j.jceh.2016.01.001
       
  • Pyoderma Gangrenosum—A New Manifestation of Wilson Disease?
    • Authors: George Naiem Ibrahiem Freg; Venisha Shah, Aabha Nagral, Ajay Jhaveri
      Abstract: Seventeen year old girl, a known case of Wilson disease presented to us with a non-healing skin ulcer followed by appearance of jaundice, ascites and progressive fatigue of 1 month duration. She was diagnosed to have Wilson disease 5 years back and had been well controlled on d-penicillamine. On enquiry, she was found to be noncompliant with her medication in the preceding 6 months. On examination, she had severe pallor, icterus with moderate ascites and oedema feet. Investigations revealed severe haemolytic anemia and deranged liver function.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-12-21
      DOI: 10.1016/j.jceh.2015.11.005
       
  • PAI-1 4G-4G, MTHFR 677TT, V Leiden 506Q, and Prothrombin 20210A in
           Splanchnic Vein Thrombosis: Analysis of Individual Patient Data From Three
           Prospective Studies
    • Abstract: There are no univocal opinions on the role of genetic thrombophilia on splanchnic vein thrombosis (SVT). We defined genetic thrombophilia the presence of one of these thrombophilic genetic factors (THRGFs): PAI-1 4G-4G, MTHFR 677TT, V Leiden 506Q, and prothrombin 20210A.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-12-18
      DOI: 10.1016/j.jceh.2015.11.002
       
  • Changes in Liver Volume in Patients with Chronic Hepatitis C Undergoing
           Antiviral Therapy
    • Authors: Julie A. Fitzpatrick; Jin Un Kim, Jeremy F.L. Cobbold, Mark J.W. McPhail, Mary M.E. Crossey, Aluel A. Bak-Bol, Ashraf Zaky, Simon D. Taylor-Robinson
      Abstract: Liver volumetric analysis has not been used to detect hepatic remodelling during antiviral therapy before. We measured liver volume (LV) changes on volumetric magnetic resonance imaging during hepatitis C antiviral therapy.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-12-18
      DOI: 10.1016/j.jceh.2015.11.004
       
  • Variceal Banding: A Lesser-Known Complication
    • Authors: Ashish Kumar Jha; Vishwa Mohan Dayal, Baraq Ahmed, Uday Kumar, Sharad Kumar
      Abstract: Band ligation is the cornerstone of the treatment of esophageal varices. Band ligation is one of the most commonly performed endoscopic procedures. Although variceal banding is mostly a safe procedure, it may be complicated by serious adverse event.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-11-26
       
  • Donor Factors Including Donor Risk Index Predict Fibrosis Progression,
           Allograft Loss, and Patient Survival following Liver Transplantation for
           Hepatitis C Virus
    • Authors: Arun Jesudian; Sameer Desale, Jonathan Julia, Elizabeth Landry, Christopher Maxwell, Bhaskar Kallakury, Jacqueline Laurin, Kirti Shetty
      Abstract: The utilization of liver transplantation (LT) is limited by the availability of suitable organs. This study aimed to assess the impact of the donor risk index (DRI) and other donor characteristics on fibrosis progression, graft, and patient survival in hepatitis C virus (HCV)-infected LT recipients.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-11-26
       
  • “Hockey Stick” may Strike Back: Hepatocellular Carcinoma on
           Noncirrhotic Liver as a Late Toxicity of Lombo-Aortic Radiotherapy for
           Seminoma. A Review Triggered by an Unusual Case
    • Authors: Clement Korenbaum; Philippe Barthelemy, Alina Onea, Pierre Salze, Jean-Emmanuel Kurtz
      Abstract: Most patients with testicular seminoma have been treated with a curative intent for decades. Second cancers after radiotherapy for testicular seminoma before 1990 are a growing issue, and are related to previous generation of dose planning and delineating strategies. Among those cancers, hepatocellular carcinoma is an extremely rare occurrence, especially when affecting patients with healthy, noncirrhotic liver. Here, we describe such a case in a patient of our institution, and subsequently review the relevant literature and large epidemiologic studies.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-11-24
       
  • Multiplex Reverse Transcriptase-PCR for Simultaneous Detection of
           Hepatitis B, C, and E Virus
    • Authors: Gunjan Garg; Deepak Kumar, Mohammad Asim, Syed Akhtar Husain, Bhudev C. Das, Premashis Kar
      Abstract: The hepatitis B virus (HBV), HCV, and HEV may occur as singly or concurrently in patients of different kind of liver disease. The rapid, reliable, and cost-effective screening of these pathogens is required for the large epidemiological studies. Therefore, a study has been planned to develop a multiplex Reverse Transcriptase-PCR assay which can be used for the screening of maximum number of pathogens at a time.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-10-30
       
  • Driving Performance Among Patients with Cirrhosis Who Drove to Their
           Outpatient Hepatology Clinic Appointments
    • Authors: Paul J. Thuluvath; Anantha Nuthalapati, Jennifer Price, Anurag Maheshwari
      Abstract: Minimal hepatic encephalopathy (MHE) may adversely affect driving skills.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-10-15
      DOI: 10.1016/j.jceh.2015.09.003
       
  • Acute-On-Chronic Liver Failure (ACLF) in Coastal Eastern India: “A
           Single-Center Experience”
    • Authors: Girish Kumar Pati; Ayaskanta Singh, Bijay Misra, Debasis Misra, Haribhakti Seba Das, Chittaranjan Panda, Shivaram Prasad Singh
      Abstract: Acute-On-Chronic liver failure (ACLF) is an emerging entity. The present study was undertaken to analyze the clinical profile and natural course of ACLF patients.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-09-01
      DOI: 10.1016/j.jceh.2015.08.002
       
  • Hepatitis C Virus (HCV) Infection in Patients with End Stage Renal
           Disease: A Study from a Tertiary Care Centre in India
    • Authors: Anil Arora; Naresh Bansal, Praveen Sharma, Vikas Singla, Varun Gupta, Pankaj Tyagi, Manish Malik, Ashish Kumar
      Abstract: Hepatitis C Virus (HCV) infection is common in patients with end stage renal disease (ESRD) and is an important cause of liver disease. We describe the demographic, clinical and biochemical profile of these patients from a tertiary care center of north India.
      Citation: Journal of Clinical and Experimental Hepatology (2015)
      PubDate: 2015-05-15
      DOI: 10.1016/j.jceh.2015.04.004
       
 
 
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