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Journal Cover Archives of Pathology & Laboratory Medicine
  [SJR: 1.158]   [H-I: 92]   [25 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 0003-9985 - ISSN (Online) 1543-2165
   Published by College of American Pathologists Homepage  [1 journal]
  • Histologic Mimics of Basal Cell Carcinoma
    • Abstract: Basal cell carcinoma (BCC) is the most common malignant neoplasm, with an estimated overall lifetime risk of 30% in the United States.1,2 Although BCC may cause extensive local tissue destruction if not adequately managed, metastasis is exceedingly rare.2 The diagnosis of BCC is usually ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • A Complete Histologic Approach to Gastrointestinal Biopsy from
           Hematopoietic Stem Cell Transplant Patients with Evidence of
           Transplant-Associated Gastrointestinal Thrombotic Microangiopathy
    • Abstract: Thrombotic microangiopathy (TMA) is characterized by microvascular endothelial cell injury and associated thrombosis. Thrombotic microangiopathy is best known as the main pathologic feature of thrombotic thrombocytopenic purpura and hemolytic uremic syndrome in the kidney.1 However, the same ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Biotin Interference in Clinical Immunoassays: A Cause for Concern
    • Abstract: To the Editor.-An increase in the use of biotin supplements by the general public is producing an increase in the number of reports of analytic interference in biotin-based immunoassays (BBAs) used to evaluate endocrine function.1,2 The fact that BBAs of similar design are currently used to ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Sustainable Development of Pathology in Sub-Saharan Africa: An Example
           from Ghana
    • Abstract: Pathology services are poorly developed in Sub-Saharan Africa. Most countries have less than 1 pathologist per 1 million inhabitants.1-3 This is a particular problem for the treatment of cancer, which is a rapidly increasing health problem in developing countries.4,5 To select the appropriate ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • The Accuracy of the Sysmex UF-1000i in Urine Bacterial Detection Compared
           with the Standard Urine Analysis and Culture
    • Abstract: Urinary tract infections (UTIs) are characterized by the presence of microbial pathogens within the urinary tract, and they represent one of the most common infections identified in both hospitalized and clinic patients. Most UTIs are easily treated without difficulty; however, in certain patient ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • If You Are Not on Social Media, Here’s What You’re Missing!
           #DoTheThing
    • Abstract: What's all this buzz about social media' Why are people tweeting and ideas trending' What am I missing'If you have these thoughts, you are not alone. In this editorial, we share our personal inroads to Twitter (Twitter Inc, San Francisco, California), explain why we believe social media has staying ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • IgG4-Related Disease: A Reminder for Practicing Pathologists
    • Abstract: IgG4-related disease (IgG4-RD) is a systemic autoimmune disorder characterized by elevated serum immunoglobulin (Ig) G4 levels and tumorlike fibroinflammatory masses with distinctive histopathologic features that almost always include infiltrates of IgG4+ plasma cells. Described initially as a form ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Primary Cutaneous Acral CD8+ T-Cell Lymphoma
    • Abstract: In 2007, Petrella and colleagues1 described 4 cases of cutaneous lymphomas, localized to the ear, with indolent clinical behavior despite high-grade morphologic findings. Each patient presented with a slow-growing nodule localized to the ear, and all cases demonstrated an indolent clinical course, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Pathologic Findings of Breast Lesions Detected on Magnetic Resonance
           Imaging
    • Abstract: During the last 20 years, magnetic resonance imaging (MRI) has emerged as the most sensitive imaging technique for detecting breast cancers. Currently it is used for evaluation of extent of disease in patients with newly diagnosed breast cancer, screening of high-risk patients for early diagnosis ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Recommendations for Pathologic Evaluation of Reduction Mammoplasty
           Specimens: Prospective Study with Systematic Tissue Sampling
    • Abstract: Reduction mammaplasty (RMP) is a very common surgical procedure. In their 2015 procedural statistics, the American Society of Plastic Surgeons reported 106 338 breast reconstructive procedures performed in the United States.1 Bilateral breast reduction is most commonly performed for symptomatic ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Mixed-Phenotype Acute Leukemia: Diagnostic Criteria and Pitfalls
    • Abstract: CLASSIFICATION OF ACUTE LEUKEMIA BASED ON LINEAGEThe first step in classification of acute leukemia is to assign lineage by resemblance to normal progenitor cells. This approach provides descriptive information about the blast cells that is useful for disease monitoring, provides clues to molecular ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Programmed Death Ligand-1 (PD-L1) Expression in Either Tumor Cells or
           Tumor-Infiltrating Immune Cells Correlates with Solid and High-Grade Lung
           Adenocarcinomas
    • Abstract: Several immune checkpoint inhibitors that target the interaction between programmed death receptor-1 (PD-1) and programmed death ligand-1 (PD-L1) have been successful in clinical trials for the treatment of non-small cell lung carcinoma (NSCLC). Nivolumab and pembrolizumab target PD-1, thereby ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Whole Slide Imaging of Large Format Histology in Prostate Pathology:
           Potential for Information Fusion
    • Abstract: To the Editor.-We read with considerable interest the contribution written by Alton Brad Farris, MD, and colleagues1 in the April 2017 issue of the Archives of Pathology & Laboratory Medicine, entitled "Whole Slide Imaging for Analytical Anatomic Pathology and Telepathology: Practical Applications ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Review of Clinical Next-Generation Sequencing
    • Abstract: Next-generation sequencing (NGS) or massively parallel sequencing, a method of simultaneously sequencing millions of fragments of DNA (or complementary DNA), has been rapidly adopted in the clinical laboratory because of its ability to simultaneously analyze several genes or gene regions with a ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Myxoinflammatory Fibroblastic Sarcoma: Review and Update
    • Abstract: BACKGROUNDMyxoinflammatory fibroblastic sarcoma (MIFS) is a rare soft tissue tumor first reported in 1998 by 3 independent investigators. Montgomery et al1 described 51 cases that they called inflammatory myxohyaline tumor of distal extremities with virocyte or Reed-Sternberg-like cells. They ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Neuroendocrine Tumors of the Breast
    • Abstract: Primary neuroendocrine tumors (NETs) of the breast are a unique but rare subtype of breast cancer.1 Neuroendocrine differentiation in breast carcinomas was first described by Feyrter and Hartmann2 in 1963, based on positive silver staining in mucinous carcinomas of the breast. In 1977 Cubilla and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Fetal Vascular Malperfusion
    • Abstract: Although fetal thrombotic vasculopathy diagnosis has been emphasized recently,1-4 it is still an underrecognized, clinically important entity that should be identified during placental examination. Fetal vascular malperfusion (FVM) is the recommended new terminology for fetal thrombotic ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Template for Reporting Results of Biomarker Testing of Specimens from
           Patients with Carcinoma of the Endometrium
    • Abstract: The College of American Pathologists (CAP) offers these templates to assist pathologists in providing clinically useful and relevant information when reporting results of biomarker testing. The CAP regards the reporting elements in the templates as important elements of the biomarker test report, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Nov 2017 00:00:00 -040
       
  • Gangliocytic Paraganglioma Is Often Misdiagnosed as Neuroendocrine Tumor
           G1
    • Abstract: To the Editor.-We wish to comment on the article by Park and Han1 on gangliocytic paraganglioma (GP) with lymph node metastasis. As they described, GP is a rare neuroendocrine tumor comprising epithelioid cells, spindle-shaped cells, and ganglionlike cells and this neuroendocrine tumor commonly ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Perceptions of Unprofessional Attitudes and Behaviors: Implications for
           Faculty Role Modeling and Teaching Professionalism during Pathology
           Residency
    • Abstract: Physician professionalism has received increased attention in recent decades as changes in health care delivery and payment, technologic advances, an explosion in information, and a more complex practice environment have all changed the practice of medicine and are changing the relationships ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Commutability of Reference Materials for [Alpha]-Fetoprotein in Human
           Serum
    • Abstract: [alpha]-Fetoprotein (AFP) is one of the most commonly used markers in the clinical diagnosis of cancer. Its expression is highly specific for liver, and it is commonly used in screening of high-risk populations for primary liver cancer and in diagnosis and monitoring of therapeutic outcome and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Pediatric Thalamic Gliomas: An Updated Review
    • Abstract: Neoplasms originating in the thalamus are rare overall (1% of all brain tumors); however, they comprise approximately 5% of pediatric intracranial tumors and approach 15% of all malignant pediatric intracranial tumors in some series. (1) Prognosis, poor overall and difficult to assess in the uneven ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Oncocytic Renal Neoplasms on Resections and Core Biopsies: Our Approach to
           This Challenging Differential Diagnosis
    • Abstract: Discussing the differential diagnosis of low-grade oncocytic renal neoplasms is difficult because the main differential is between low-grade oncocytic renal cell carcinomas, which generally behave indolently, and benign oncocytomas. In general, low-grade oncocytic renal cell carcinomas have a real ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Simple Mucinous Cyst of the Pancreas: Review and Update
    • Abstract: HISTORICAL PERSPECTIVEMucinous pancreatic cystic lesions are generally considered to be precursor lesions of pancreatic adenocarcinoma owing to their common association or coexistence with cancer.1 The only 2 mucinous pancreatic cystic neoplasms recognized by the World Health Organization (WHO) are ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • SATB2 as an Immunohistochemical Marker for Colorectal Adenocarcinoma: A
           Concise Review of Benefits and Pitfalls
    • Abstract: Colorectal cancer is the fourth most common cancer and the second leading cause of cancer death in the United States. (1) Pathologic identification of colonic adenocarcinoma presenting as a mass in the colon does not generally pose diagnostic difficulties; however, approximately 3% to 5% of all new ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Serous Tubal Intraepithelial Carcinoma or Not' Metastases to Fallopian
           Tube Mucosa Can Masquerade as in Situ Lesions
    • Abstract: Worldwide, ovarian carcinoma is the seventh most common cancer and the eighth most common cause of death from cancer in women. (1) High-grade serous carcinoma (HGSC) is the most common and most lethal type of ovarian carcinoma. For many decades it was assumed that HGSCs arise from the ovarian ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Comparison of Estrogen and Progesterone Receptor Antibody Reagents Using
           Proficiency Testing Data
    • Abstract: Analysis of estrogen receptor (ER) and progesterone (PgR) expression in breast cancer began more than 30 years ago, and indeed these were the first widely applied prognostic and predictive biomarkers in cancer therapy. (1) Estrogen receptor-expressing breast cancers tend to have better prognosis ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Localization for Breast Surgery: The Next Generation
    • Abstract: In the 1970s, the development of screen-film mammography and publication of studies showing decrease in mortality from breast cancer in women who were offered screening led to the rise of mammography. With screening mammography, nonpalpable abnormalities were detected that required biopsy. Before ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Initial Diagnostic Workup of Acute Leukemia: Guideline from the College of
           American Pathologists and the American Society of Hematology
    • Abstract: The laboratory evaluation of patients suspected of having acute leukemia (AL) is complex and has evolved significantly with the incorporation of advanced laboratory techniques. The first broadly accepted classification in modern history was that of the French-American-British (FAB) cooperative ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Pathologists’ Computer-Assisted Diagnosis: A Mock-Up of a Prototype
           Information System to Facilitate Automation of Pathology Sign-Out
    • Abstract: Whole-slide imaging (WSI), initially introduced at the turn of the 21st century, is just now beginning to gain traction in routine clinical pathology workflow.1-3 Currently, the bulk of existing platforms is used for highly specialized applications such as telepathology, expert or second-opinion ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Contributions from University of Michigan 2016 New Frontiers in Pathology
           Conference
    • Abstract: Every autumn the Department of Pathology at the University of Michigan (UM; Ann Arbor, Michigan) organizes a case-based continuing medical education conference directed toward an audience of community and academic pathologists and trainees with the intent of providing up-to-date and cutting-edge ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Pathologists' Computer-Assisted Diagnosis: A Mock-Up of a Prototype
           Information System to Facilitate Automation of Pathology Sign-Out
    • Abstract: Whole-slide imaging (WSI), initially introduced at the turn of the 21st century, is just now beginning to gain traction in routine clinical pathology workflow. (1-3) Currently, the bulk of existing platforms is used for highly specialized applications such as telepathology, expert or second-opinion ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Initial Diagnostic Workup of Acute Leukemia Guideline from the College of
           American Pathologists and the American Society of Hematology
    • Abstract: The laboratory evaluation of patients suspected of having acute leukemia (AL) is complex and has evolved significantly with the incorporation of advanced laboratory techniques. The first broadly accepted classification in modern history was that of the French-American-British (FAB) cooperative ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Serous Tubal Intraepithelial Carcinoma or Not': Metastases to
           Fallopian Tube Mucosa Can Masquerade as in Situ Lesions
    • Abstract: Worldwide, ovarian carcinoma is the seventh most common cancer and the eighth most common cause of death from cancer in women.1 High-grade serous carcinoma (HGSC) is the most common and most lethal type of ovarian carcinoma. For many decades it was assumed that HGSCs arise from the ovarian surface ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Commutability of Reference Materials for '-Fetoprotein in Human Serum
    • Abstract: a-etoprotein (AFP) is one of the most commonly used a-F markers in the clinical diagnosis of cancer. Its expression is highly specific for liver, and it is commonly used in screening of high-risk populations for primary liver cancer and in diagnosis and monitoring of therapeutic outcome and tumor ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Oct 2017 00:00:00 -040
       
  • Giant Cell Arteritis of the Breast
    • Abstract: Giant cell arteritis (GCA) is an inflammatory lesion of the large- and medium-sized arteries, which usually involves the cranial arteries of older women. Patients commonly present with temporal headaches, visual impairment, fever, scalp tenderness, jaw claudication, and polymyalgia rheumatica ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Analytic Validation of Immunohistochemical Assays: A Comparison of
           Laboratory Practices before and after Introduction of an Evidence-Based
           Guideline
    • Abstract: The College of American Pathologists (CAP) Pathology and Laboratory Quality Center (the CAP Center) develops and maintains evidence-based laboratory practice guidelines (LPGs) that follow the US Institute of Medicine's Clinical Practice Guidelines We Can Trust standards.1 In 2014, the CAP Center ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Comparison of Clinical Diagnoses and Autopsy Findings: Six-Year
           Retrospective Study
    • Abstract: Hospital autopsy rates in the United States declined from 30% to 40% in the 1960s1 to 8% in the early 2000s.2 Multiple factors, such as the elimination of the hospital autopsy rate requirement in 1972, lack of reimbursement, cultural and religious objections by families, and increasing workload for ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Analytic Validation of Immunohistochemistry Assays: New Benchmark Data
           from a Survey of 1085 Laboratories
    • Abstract: In 2015, the College of American Pathologists (CAP) conducted a survey of laboratory practices to examine the current state of immunohistochemical assay (IHC) validation procedures, assess general awareness of the CAP's 2014 evidence-based laboratory practice guideline (LPG) on IHC validation,1 and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Practical Immunohistochemistry in Neoplastic Pathology of the
           Gastrointestinal Tract, Liver, Biliary Tract, and Pancreas
    • Abstract: Malignant neoplasms of the gastrointestinal (GI) tract, liver, biliary tract, and pancreas are the most common cancers of the body, with an estimated 304 930 new cases and an estimated 153 030 deaths in the year 2016 in the United States.1 Most of these neoplasms are aggressive malignancies with ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Practical Applications of Immunohistochemistry in the Diagnosis of
           Genitourinary Tumors
    • Abstract: Immunohistochemical techniques with a variety of markers have been applied frequently in the diagnosis of neoplasms and have become indispensable in some situations.1,2 In this article, we review the commonly used immunohistochemical markers in the diagnosis of genitourinary tumors. This review ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Updates on Immunohistochemical and Molecular Markers in Selected Head and
           Neck Diagnostic Problems
    • Abstract: The head and neck branch of surgical pathology embraces diseases arising from the ear, nose, sinuses, mouth, pharynx, larynx, trachea, thyroid, parathyroid, and salivary glands. The most common malignant neoplasm in these regions is squamous cell carcinoma. However, owing to the complex anatomic ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • The Gold Standard Paradox in Digital Image Analysis: Manual versus
           Automated Scoring as Ground Truth
    • Abstract: Anatomic pathology, as a discipline, seeks to render a precise and complete diagnosis of lesions produced by a particular disease, to the correct patient, in a timely fashion, and in a way that is understandable and useful to the physician treating the patient.1 In a research setting, this ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Application of Immunohistochemistry in the Diagnosis of Pulmonary and
           Pleural Neoplasms
    • Abstract: Biopsies of lung and pleural neoplasms play an important role in the characterization and staging of lung cancers, particularly for patients with advanced disease (stages III and IV) and for patients who are not candidates for surgical procedures. Clinical and imaging correlation in conjunction ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Diagnostic Algorithm of Common Mature B-Cell Lymphomas by
           Immunohistochemistry
    • Abstract: Immunophenotyping with immunohistochemistry (IHC) remains an essential diagnostic tool for mature lymphomas, in combination with cytogenetics, molecular genomics, and clinical, radiologic, and other laboratory tests. As a technique, IHC is relatively easy to perform and is readily available in ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Fri, 01 Sep 2017 00:00:00 -040
       
  • Best Practices in Immunohistochemistry in Surgical Pathology and
           Cytopathology
    • Abstract: This special section on diagnostic immunohistochemistry (IHC) consists of a series of 10 articles from the first Chinese American Pathologists Association (CAPA) diagnostic pathology course, Best Practices in Immunohistochemistry in Surgical Pathology and Cytopathology, which took place in ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Soft Tissue Tumor Immunohistochemistry Update: Illustrative Examples of
           Diagnostic Pearls to Avoid Pitfalls
    • Abstract: Current 2013 World Health Organization (WHO) classification of tumors of soft tissue arranges these tumors into 12 groups according to their histiogenesis as follows: adipocytic, fibroblastic/myofibroblastic, fibrohistiocytic, smoothmuscle, pericytic (perivascular), skeletal-muscle, vascular, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • A Novel Automated Slide-Based Technology for Visualization, Counting, and
           Characterization of the Formed Elements of Blood: A Proof of Concept Study
           
    • Abstract: The most commonly performed clinical laboratory test is the complete blood count (CBC). Currently, laboratory CBC systems obtain cell counts and morphologic information by maintaining the blood cells in a liquid "flow" and by using the Coulter impedance-based orifice or laser-based cytometry. In ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Fabry Nephropathy
    • Abstract: Fabry disease is a panethnic lipidosis first described in 1898 by Johannes Fabry and William Anderson. It is the second most frequent lysosomal storage disease after Gaucher disease. Its incidence rate is estimated at between 1 in 40 000 and 1 in 117 000 births worldwide by the Fabry Outcome ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Cutaneous and Superficial Soft Tissue CD34^sup +^ Spindle Cell
           Proliferation
    • Abstract: Cutaneous and superficial soft tissue spindle cell proliferation is a commonly encountered diagnostic problem in the daily practice of pathologists and dermatopathologists. Among the spindle cell neoplasms, CD34+ lesions constitute a unique heterogeneous group spanning from fibrohistiocytic, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Application of Immunohistochemistry in Undifferentiated Neoplasms: A
           Practical Approach
    • Abstract: Advances in interventional technology have enhanced the ability to safely sample deep-seated suspicious lesions by fine-needle aspiration (FNA) procedures as well as core needle biopsies. In addition, the discovery of specific genomic alterations in tumors has led to the development of targeted ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Evaluation of Testing of Acute Leukemia Samples: Survey Result from the
           College of American Pathologists
    • Abstract: The 2016 revision to the World Health Organization (WHO) classification of acute leukemia (AL) illustrates the increasing complexity driving the classification of AL.1 The classification includes 23 subtypes of acute myeloid leukemia (AML) and 2 provisional entities, 9 subtypes of acute ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Hippocampal Sclerosis in Older Patients: Practical Examples and Guidance
           with a Focus on Cerebral Age-Related TDP-43 with Sclerosis
    • Abstract: Autopsy-based studies of cognitive impairment in the older US population (>65 years of age1) show that most dementias arise in the setting of 2 or more different neuropathologies.2,3 Among the common dementia-related diseases, cerebrovascular,4 Alzheimer disease (AD), and Lewy body disease (LBD) ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Update on Immunohistochemical Analysis in Breast Lesions
    • Abstract: DIFFERENTIAL DIAGNOSIS IN NONPAPILLARY AND PAPILLARY BREAST LESIONS BY IMMUNOHISTOCHEMISTRYDistinguishing Between Usual Ductal Hyperplasia and Atypical Ductal Hyperplasia/Low-Grade Ductal Carcinoma In SituUsual ductal hyperplasia (UDH) and atypical ductal hyperplasia (ADH)/low-grade ductal ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Aug 2017 00:00:00 -040
       
  • Evaluation of the Afirma Gene Expression Classifier in Repeat
           Indeterminate Thyroid Nodules
    • Abstract: Thyroid nodules are a common clinical concern. Increasing use of diagnostic imaging likely explains a large part of the increased incidence of thyroid nodules and the subsequent diagnosis of thyroid cancer that has been observed during the last 3 decades.1,2Ultrasound-guided fine-needle aspiration ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Challenges of Frozen Section in Thoracic Pathology: Lepidic Lesions,
           Limited Resections, and Margins
    • Abstract: The use of frozen section in many subspecialty areas of pathology has diminished and its role altered as a result of changes in surgical technique and approach. In addition, although it is overall an accurate process,1 experience with frozen section has identified pitfalls in its execution that ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Pulmonary Manifestations of Acute Lung Injury: More Than Just Diffuse
           Alveolar Damage
    • Abstract: Acute respiratory distress syndrome (ARDS) is a significant cause of pulmonary morbidity and mortality. As a clinical term, acute lung injury (ALI) was previously defined along with ARDS by the 1994 North AmericanEuropean consensus classification. Both met certain clinical and radiographic criteria ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Transbronchial Cryobiopsy in Diffuse Lung Disease: Update for the
           Pathologist
    • Abstract: Transbronchial cryobiopsies are now used at many centers around the world to assess patients with diffuse lung disease,1-13 and this has implications for pathologists who will encounter them.WHAT IS A TRANSBRONCHIAL LUNG CRYOBIOPSY'Put simply, a cryoprobe is inserted into the lung, cooled below ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Solid Pseudopapillary Neoplasm of the Pancreas: A Rare Entity with Unique
           Features
    • Abstract: Solid pseudopapillary neoplasm (SPN), an uncommon entity first described by Frantz in 1959,1 reportedly accounts for between 2% and 3% of pancreatic neoplasms and 0.9% to 2.7% of exocrine pancreatic neoplasms.2,3 This neoplasm, which has had a variety of names such as solid and papillary epithelial ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Diagnostic Approach to Advanced Fibrotic Interstitial Lung Disease:
           Bringing Together Clinical, Radiologic, and Histologic Clues
    • Abstract: In mammals, fibrosis is a final consequence of cell and/or matrix injury by virtually any mechanism, including traumatic, thermal, chemical, hypoxic, infectious, and immune-mediated insults, among others. Fibrosis serves not only as a repair mechanism to restore the integrity of the native tissue, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Management of the Solitary Pulmonary Nodule
    • Abstract: A solitary pulmonary nodule (SPN) is defined as a single, well-circumscribed lesion evident on radiographic imaging and surrounded by lung parenchyma that measures 3 cm or less.1-3 A similar lesion that measures greater than 3 cm is classified as a lung mass. Although they are entities along the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Interstitial Pneumonia with Autoimmune Features: Value of Histopathology
    • Abstract: Interstitial lung diseases (ILDs) often occur as a complication of connective tissue disease (CTD). It has been recognized that patients with ILD may demonstrate clinical or serologic features suggestive of an underlying autoimmune process but not fulfill diagnostic criteria for a defined CTD. The ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Analytic and Clinical Validation of an Ultrasensitive, Quantitative
           Polymerase Chain Reaction Assay for EGFR Mutation Analysis with
           Circulating Tumor DNA
    • Abstract: Non-small cell lung cancer (NSCLC) is the leading cause of cancer-related mortality worldwide, and most patients are diagnosed at advanced stages and have poor prognoses.1 The status is being changed by the clinical application of epidermal growth factor receptor (EGFR) tyrosine kinase ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Frontiers in Thoracic Pathology
    • Abstract: In this third special section of the Princeton Integrated Pathology Symposium (PIPS), we present 7 articles as the proceedings of the Third PIPS: Thoracic Pathology. This symposium, co-organized by Philip T. Cagle, MD, and me, took place at the University Medical Center of Princeton, Plainsboro, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Implementation of Whole Slide Imaging for Clinical Purposes: Issues to
           Consider from the Perspective of Early Adopters
    • Abstract: Interest in the use of digital pathology in clinical practice continues to grow. Digital pathology is being used for clinical work such as telepathology, education, and research.1 Telepathology is defined as the transmission of pathology images and patient information for a variety of clinical ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Morphological Features and Prognostic Significance of ARID1A-Deficient
           Esophageal Adenocarcinomas
    • Abstract: Esophageal adenocarcinomas (EACs) are morphologically heterogeneous tumors.1-3 This phenotypic diversity is reflected in the heterogeneous molecular pathways described in EACs. Mutations of tumor suppressor genes TP534 and pió5; dysregulation of proto-oncogenes EGF,6 EGFR,7 TGF,8 and HER29; and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Lung Carcinoma Staging Update
    • Abstract: The International Association for the Study of Lung Cancer (IASLC) Staging Committee recently published its proposed changes in lung carcinoma staging, which will be included in the 8th edition of the American Joint Committee on Cancer (AJCC)/Union for International Cancer Control criteria. The ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Jul 2017 00:00:00 -040
       
  • Gastric Angiolipoma: A Rare Entity
    • Abstract: Angiolipoma was delineated as a new entity in 1960 because of its different clinicopathologic features from those of regular lipoma.1 It is a benign tumor composed of adipose tissue and proliferating blood vessels and is commonly found in the subcutaneous tissue of the trunk and extremities.2,3 ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Development and Validation of Targeted Next-Generation Sequencing Panels
           for Detection of Germline Variants in Inherited Diseases
    • Abstract: With the advent of massively parallel sequencing, commonly called next-generation sequencing (NGS), methodologies, the number of genes implicated in human disease has increased substantially in the last decade. The increase in gene discovery has led to a surge in the number of clinical laboratory ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Targeted Next-Generation Sequencing for Human Leukocyte Antigen Typing in
           a Clinical Laboratory: Metrics of Relevance and Considerations for Its
           Successful Implementation
    • Abstract: Advances in technology have resulted in the evolution of human leukocyte antigen (HLA) typing from serologic-based methods to molecular methods. This has enabled the characterization of HLA antigens and alleles.1 The HLA antigens are highly immunogenic and mostly polymorphic,2 and matching HLA ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Delta Check Practices and Outcomes: A Q-Probes Study Involving 49 Health
           Care Facilities and 6541 Delta Check Alerts
    • Abstract: The delta check is a measurement of the difference between a patient's sequential test results. A largerthan-expected interval change in results may indicate a testing problem associated with either the former or the current specimen and prompt an investigation before results are reported. Delta ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Immunohistochemical Detection of Hairy Cell Leukemia in Paraffin Sections:
           The Role of Pax5 and CD103 Double Staining to Improve Specificity and
           Sensitivity
    • Abstract: CD103 is an integrin aE chain that upon heterodimerization with the integrin b7 constitutes the receptor for Ecadherin. This interaction plays a role in various cellular interactions within the immune system.1 CD103 is expressed on intraepithelial T cells, some subsets of memory T cells (CD8 ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Programmed Death Ligand-1 (PD-L1) Expression in the Programmed Death
           Receptor-1 (PD-1)/PD-L1 Blockade: A Key Player against Various Cancers
    • Abstract: During the past several decades, the efforts of antitumor immune therapy have been focused on identification of specific tumor antigens to augment antitumor immunity. However, this approach has been constantly challenged by the complexity and diversity of gene mutation and protein modification ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • FDA Oversight of Laboratory-Developed Tests: Where Are We Now'
    • Abstract: On November 18, 2016, the US Food and Drug Administration (FDA) announced it would not issue a final guidance for laboratory-developed tests (LDTs).1 The draft guidance for LDTs, released in 2014, had generated vigorous criticisms and praise, with stakeholders putting great effort into analyzing, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Validation of OncoPanel: A Targeted Next-Generation Sequencing Assay for
           the Detection of Somatic Variants in Cancer
    • Abstract: The understanding of cancer as a genomic disease, coupled with the introduction of targeted therapeutic agents to treat cancer, has propelled the genomic profiling of tumor samples to aid in assigning diagnosis and prognosis as well as selecting treatment. The identification of actionable cancer ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Development and Validation of Clinical Whole-Exome and Whole-Genome
           Sequencing for Detection of Germline Variants in Inherited Disease
    • Abstract: The onset of next-generation sequencing (NGS) technology has resulted in a vast increase in genetic diagnostic testing available to the ordering physician. Whole-exome sequencing (WES) has become available as a diagnostic test performed in Clinical Laboratory Improvement Amendments-certified and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • The Next Generation of Molecular Pathology Is Here: Validation of
           Next-Generation Sequencing Technology for Clinical Molecular Testing
           across Multiple Different Disciplines
    • Abstract: Massively parallel sequencing technologies, commonly known as next-generation sequencing (NGS), have revolutionized molecular diagnostic testing. Not since the advent of the polymerase chain reaction (PCR) has there been such a dramatic transformation in the capabilities of molecular analysis of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Medicare’s New Quality Payment Program Has Started-Are You
           Ready'
    • Abstract: A 2016 survey from Deloitte found that half of physicians were unaware of important changes to the Medicare reimbursement policy that were set to begin on January 1, 2017, and thus questioned the readiness of hundreds of thousands of physicians expected to participate and meet certain performance ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Chondroblastoma: An Update
    • Abstract: Chondroblastoma (CBT) is a rare, cartilage-producing bone tumor that tends to occur in the long bones of skeletally immature individuals. It was originally described by Ewing in 1928 as a "calcifying giant cell tumor." 1 Subsequent terms have included epiphyseal chondromatous giant cell tumor,2 and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Integration of Technical, Bioinformatic, and Variant Assessment Approaches
           in the Validation of a Targeted Next-Generation Sequencing Panel for
           Myeloid Malignancies
    • Abstract: Next-generation sequencing (NGS), or massively parallel sequencing, analysis of myeloid malignancies, including acute myeloid leukemias (AMLs),1-5 myelodysplastic syndromes (MDSs),6 myeloproliferative neoplasms (MPNs),1 and MDS/MPNs,7 has yielded a number of significant advances in the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Validation of Metagenomic Next-Generation Sequencing Tests for Universal
           Pathogen Detection
    • Abstract: Accurate diagnosis of infections, such as pneumonia, meningitis/encephalitis, and sepsis, in hospitalized patients is an area of great clinical unmet need. More than 1 million patients are admitted for pneumonia alone in the United States per year, incurring ~$10 billion in associated costs.1,2 For ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Pathologists’ Perspectives on Disclosing Harmful Pathology Error
    • Abstract: Communicating to patients that a harmful error has occurred in their care is a daunting task for any physician.1 The recent Institute of Medicine (IOM) report on diagnostic error emphasized the importance of communication and error disclosure in medicine. The report details tactics for effective ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • The Significance of Lymphovascular Invasion of the Spermatic Cord in the
           Absence of Cord Soft Tissue Invasion
    • Abstract: In the United States, testicular cancer is the most common cancer in men between the ages of 15 and 40 years.1 Although the incidence of testicular cancer has been increasing during the past century, because of advances in therapy, the prognosis for most patients is excellent.1 Surgery, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Serum Bilirubin Concentrations in Patients with Takayasu Arteritis
    • Abstract: Takayasu arteritis (TA) is a chronic, recurrent, inflammatory vasculitis characterized by granulomatous inflammation in the vessel wall, and mainly affects young females.1 The aortic arch and its primary branches, such as the ascending aorta, abdominal aorta, and thoracic descending aorta, are ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Jun 2017 00:00:00 -040
       
  • Straw Men, Deep Learning, and the Future of the Human Microscopist:
           Response to ''Artificial Intelligence and the Pathologist: Future
           Frenemies'''
    • Abstract: We are pleased the authors of ''Artificial Intelligence and the Pathologist: Future Frenemies have taken an interest in our essay ''AlphaGo, Deep Learning, and the Future of the Human Microscopist But we find ourselves in the odd position of being challenged to defend positions we never expressed ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Mon, 01 May 2017 00:00:00 -040
       
  • Reporting Results of Molecular Tests: A Retrospective Examination of BRAF
           Mutation Reporting
    • Abstract: The fields of genomics and molecular pathology are evolving rapidly with increasing complexity of available technologies. Reporting the results of molecular testing must be comprehensive and yet concise so that the information gleaned accurately conveys the findings to clinicians and other ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Mon, 01 May 2017 00:00:00 -040
       
  • AlphaGo, Deep Learning, and the Future of the Human Microscopist
    • Abstract: In March of last year, Google's (Menlo Park, California) artificial intelligence (AI) computer program AlphaGo beat the best Go player in the world, 18-time champion Lee Se-dol, in a tournament, winning 4 of 5 games.1 At first glance this news would seem of little interest to a pathologist, or to ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Mon, 01 May 2017 00:00:00 -040
       
  • Splenic Epstein-Barr Virus-Associated Inflammatory Pseudotumor
    • Abstract: Inflammatory pseudotumor (IPT) is a mass lesion of uncertain etiology that occurs in multiple anatomic sites. Inflammatory pseudotumor of the spleen is an uncommon lesion.1,2 Regardless of location, IPTs share certain histologic features. They are composed, in varying proportions, of spindle cells ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Mon, 01 May 2017 00:00:00 -040
       
  • Low-Grade Sinonasal Sarcoma with Neural and Myogenic Features: A Recently
           Discovered Entity with Unique Features and Diagnostic Challenge
    • Abstract: Since the publication of the World Health Organization classification of head and neck tumors,1 a number of new sinonasal lesions have been described in the literature, including seromucinous hamartoma, human papillomavirus- related carcinoma with adenoid cysticlike features, and low-grade ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Mon, 01 May 2017 00:00:00 -040
       
  • The Evolving Classification of Pulmonary Hypertension
    • Abstract: Our understanding of pulmonary hypertension (PH) has grown during the past century and significantly progressed, particularly in the past few decades. Changes in the classification of PH have evolved with the technologic advancements in medical diagnostics, pharmacologic management, and molecular ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Mon, 01 May 2017 00:00:00 -040
       
  • Professional Practice Evaluation for Pathologists: The Development, Life,
           and Death of the Evalumetrics Program
    • Abstract: In 2008, the Joint Commission (JC) implemented a new standard mandating evaluation of practitioners' professional performance as part of the process of granting and maintaining practice privileges in a health care organization.1-3 The mandate included 2 distinct forms of evaluation: (1) Ongoing ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • The Impact of New Technologic and Molecular Advances in the Daily Practice
           of Gastrointestinal and Hepatobiliary Pathology
    • Abstract: The hematoxylin-eosin (H&E)-stained slide is still the main diagnostic tool used by surgical pathologists. Although the basic practice of interpreting an H&E-stained section has not changed over the years, how we incorporate the findings into a meaningful and complete diagnosis has become more ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • New-Generation Thromboelastography: Comprehensive Evaluation of Citrated
           and Heparinized Blood Sample Storage Effect on Clot-Forming Variables
    • Abstract: Assessment of hemostasis with a thromboelastography (TEG) system has been used clinically for 50 years to identify, monitor, and guide treatment of coagulopathies in both laboratories and in point-of-care facilities.1 By individualizing goal-directed coagulation management, it is possible to reduce ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • Recent Developments in Surgical Pathology of the Uterine Corpus
    • Abstract: Over the past few years, numerous significant developments have taken place regarding the classification, terminology, and daily surgical pathology practice of tumors of uterine corpus. The morphology-based classification of endometrial carcinomas (ECs) by the 2014 World Health Organization (WHO) ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • SP174, NRAS Q61R Mutant-Specific Antibody, Cross-Reacts with KRAS Q61R
           Mutant Protein in Colorectal Carcinoma
    • Abstract: The RAS proto-oncogenes (HRAS, KRAS, and NRAS) encode HRAS, KRAS 4A, KRAS 4B, and NRAS, 4 distinct but closely related and highly homologous proteins. These enzymes, located on the inner surface of the cell membrane, represent GDP/GTP-regulated switches that convey extracellular signals and play a ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • Benchmarking after Large-Scale, Comparative Data Analysis Improves the Use
           of Laboratory Tests: Lessons from the REDCONLAB Initiative
    • Abstract: To the Editor.-Quality tools and information technologies can be used to manage metadata regarding the use of laboratory tests. Benchmarking and the laboratory information management system can be used to search and manage data from large laboratory patient data bases.The Appropriate Utilization of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • Whole Slide Imaging for Analytical Anatomic Pathology and Telepathology:
           Practical Applications Today, Promises, and Perils
    • Abstract: Pathologists make crucial diagnoses and issue reports that directly affect patient care, primarily using microscopes and hematoxylin-eosin (H&E)-stained tissue with techniques that have not changed since the 19th century1,2 and that are likely to remain for decades to come with supplements from the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • Acquired Cystic Disease-Associated Renal Cell Carcinoma: Review of
           Pathogenesis, Morphology, Ancillary Tests, and Clinical Features
    • Abstract: Acquired cystic disease-associated renal cell carcinoma (ACD-RCC) is a relatively new subtype of RCC that characteristically arises in individuals with acquired cystic kidney disease (ACKD) in the setting of end-stage renal disease (ESRD). It is regarded as the predominant subtype of RCC occurring ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • To Fast or Not to Fast'
    • Abstract: Comments on the Consensus Statement From the European Atherosclerosis Society/European Federation of Clinical Chemistry and Laboratory MedicineThe European Atherosclerosis Society/European Federation of Clinical Chemistry and Laboratory Medicine recently published a consensus statement promoting ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
  • Template for Reporting Results of Biomarker Testing of Specimens from
           Patients with Thyroid Carcinoma
    • Abstract: The College of American Pathologists (CAP) offers these templates to assist pathologists in providing clinically useful and relevant information when reporting results of biomarker testing. The CAP regards the reporting elements in the templates as important elements of the biomarker test report, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Apr 2017 00:00:00 -040
       
 
 
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