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Journal Cover Archives of Pathology & Laboratory Medicine
  [SJR: 1.258]   [H-I: 80]   [17 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 0003-9985 - ISSN (Online) 1543-2165
   Published by College of American Pathologists Homepage  [1 journal]
  • Uniform Labeling of Blocks and Slides in Surgical Pathology: Guideline
           from the College of American Pathologists Pathology and Laboratory Quality
           Center and the National Society for Histotechnology
    • Abstract: The diagnosis of biopsy and surgical tissue samples depends to a great extent and often entirely on the interpretation by the pathologist of the microscopic features of the case as evaluated in sections obtained from paraffin blocks and placed on glass slides. It is therefore imperative for these ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Clinical Applications of 4-Factor Prothrombin Complex Concentrate: A
           Practical Pathologist's Perspective
    • Abstract: Anonactivated, 4-factor prothrombin complex concentrate (4F-PCC) known as Kcentra (CSL Behring, Kankakee, Illinois) has been approved in the United States for the reversal of vitamin K antagonist (VKA) anticoagulation in patients with major acute hemorrhage, or in patients who require urgent ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Value of Molecular Tests in Cytologically Indeterminate Lesions of Thyroid
    • Abstract: Thyroid fine-needle aspiration (FNA) has become the effective first-line workup of thyroid nodules. Since its initial clinical application, the number of patients undergoing thyroidectomy has decreased 25%, and the yield of carcinoma in patients who undergo surgery has increased from 15% to at ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Microscopic Image Photography Techniques of the Past, Present, and Future
    • Abstract: The field of pathology is driven by images, both in gross pathology and in microscopic findings. Trainees learn from exposure to a variety of pathologic entities through their clinical duties, in textbooks, and from online tutorials, lectures, and interdepartmental conferences. Practicing ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Diagnostic Discrepancies in Mandatory Slide Review of Extradepartmental
           Head and Neck Cases: Experience at a Large Academic Center
    • Abstract: Medical errors are a major issue for patient safety and occur when a health care provider makes an inaccurate or incomplete diagnosis, chooses an inappropriate type of care, fails to properly administer that care, or counsels the patient in an inaccurate manner for their disease or prognosis.1 ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Fine-Needle Aspiration Biopsy of Salivary Gland Lesions
    • Abstract: Masses or cystic lesions of salivary glands have a wide range of differential diagnoses, from inflammatory response to neoplasm and to less common causes of infection.1 The World Health Organization has described 45 morphologic types of primary salivary gland tumors.2 Fine-needle aspiration (FNA) ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Pathology Education: Moving On
    • Abstract: The study of human disease has led to new discoveries and insights, resulting in improved patient care. Early scientific inquiries were inspired by the observations of anatomists, who noted morphologic deviations from normal in postmortem dissections.1 Once morbid anatomy was found to correlate ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Challenges to Biomarker Testing for PD-1/PD-L1 Checkpoint Inhibitors for
           Lung Cancer
    • Abstract: Immune checkpoint therapy shows great promise for many cancer patients and includes cytotoxic T lymphocyte-associated antigen 4 (CFLA-4) checkpoint inhibitors and PD-i (programmed death receptor-i)/PD-Li (programmed death-ligand 1) checkpoint inhibitors.t2 Several PD-i/PD-Li checkpoint inhibitors ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Expression of Angiogenic Factors in Invasive Retinoblastoma Tumors Is
           Associated with Increase in Tumor Cells Expressing Stem Cell Marker Sox2
    • Abstract: Retinoblastoma is the most common intraocular malignant neoplasm in children, with most cases initiated by a mutation of the tumor-suppressor gene RB1 .1-3 Despite extensive research efforts, retinoblastoma-associated mortality rate remains around 70%, especially in lower-income countries.4 These ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Comparison of Oncotype DX Recurrence Score by Histologic Types of Breast
           Carcinoma
    • Abstract: Breast cancer accounts for more than 232 000 newly diagnosed cases and approximately 40 000 deaths in women in 2014 within the United States alone.1 An estimated 50% of these total cases will be estrogen receptor (ER) positive, lymph node negative.2 The development and improvement of adjuvant ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Differential Diagnosis of Necrotizing Sinonasal Lesions
    • Abstract: The sinonasal tract may be involved by numerous neoplastic and nonneoplastic lesions, which can result in significant necrosis of the mucosa and associated surrounding structures. These processes can lead to destruction of the nasal septum, and subsequently facial deformities and even death if the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Telepathology Impacts and Implementation Challenges: A Scoping Review
    • Abstract: Telepathology is defined by the American Telemedicine Association as ''the electronic multimedia communication across a network of pathology-related information, between 2 or more locations for use-cases between pathologists and/or qualified laboratory personnel, and may include involvement by ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Performance Characteristics of Adenoid Cystic Carcinoma of the Salivary
           Glands in Fine-Needle Aspirates: Results from the College of American
           Pathologists Nongynecologic Cytology Program
    • Abstract: Adenoid cystic carcinoma (ACC) is a relatively rare, slowgrowing, malignant salivary gland tumor with poor long-term prognosis.1 Cytologic features of ACC have been well described2-14; however, the reproducibility of this diagnosis in fine-needle aspirates (FNAs) of the salivary gland has not been ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Mammary Hibernoma: A Rare Entity
    • Abstract: Hibernoma is a benign lipomatous tumor made of brown fat, a specialized form of adipose tissue. Although these tumors can arise in various sites, mammary hibernomas remain extraordinarily uncommon, with fewer than 10 cases reported thus far in the English literature.1-5 This review discusses the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Who Will Do My Autopsy?
    • Abstract: To the Editor.-As a recently retired pathology chief of a large-volume anatomic and clinical laboratory service at a community hospital, I want to applaud Dr Stephen A. Geller's editorial letter, ''Who Will Do My Autopsy1 I share his frustration and concerns with the state of autopsy pathology ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • The Differential Diagnosis of Sinonasal/Nasopharyngeal
           Neuroendocrine/Neuroectodermally Derived Tumors
    • Abstract: Avariety of different neoplastic tumors including those with epithelial, mesenchymal, or neuroectodermal differentiation may arise in the sinonasal tract and should be considered in the differential diagnosis of sinonasal tract neoplasms.1-4 Neuroendocrine/neuroectodermally derived sinonasal tumors ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Edoxaban: Efficacy, Laboratory Monitoring, and Approach to Reversal
    • Abstract: To the Editor.-In an article,1 published in the May 2015 edition of Archives of Pathology & Laboratory Medicine, the efficacy, methods of laboratory monitoring, and approach to emergent ''reversal'' of warfarin, dabigatran, rivaroxaban, and apixaban were discussed. However, a third direct factor Xa ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Updates on Surgical and Molecular Pathology concerning Head and Neck
           Diseases
    • Abstract: The following 4 review articles are derived from the lectures presented at the First Princeton Integrated Pathology Symposium: Head and Neck Pathology, which took place at University Medical Center of Princeton, Plainsboro, New Jersey, on February 9, 2014. It is our honor and privilege to edit this ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Dec 2015 00:00:00 -050
       
  • Glandular Lesions of the Cervix in Clinical Practice: A Cytology,
           
    • Abstract: The Papanicolaou (Pap) test has substantially decreased cervical cancer rates and mortality since its widespread implementation in the early 1970s.1 In 1975 the incidence of cervical cancer was 14.8 per 100 000 women in the United States and in 2011 the incidence was 6.2 cases per 100 000 women,2,3 ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Cancer as the Disintegration of Robustness: Population-Level Variance in
           Gene Expression Identifies Key Differences between Tobacco- and
           HPV-Associated Oropharyngeal Carcinogenesis
    • Abstract: Head and neck squamous cell carcinoma is the seventh most common cancer worldwide.1 Risk factors include tobacco use, alcohol consumption, and human papillomavirus (HPV) infection (predominantly HPV type 16).2-4 Human papillomavirus-positive tumors are frequently found within the oropharynx.3 ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Epigenetic Mechanisms of Human Papillomavirus-Associated Head and Neck
           Cancer
    • Abstract: Growing evidence suggests that as many as half of all oropharyngeal squamous cell carcinomas (OPSCCs) harbor human papillomavirus (HPV) infections.1 Human papillomavirus DNA in these tumors (overwhelmingly genotype 16, a high-risk type also found in most cervical cancers) is often transcriptionally ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Emerging Concepts in Head and Neck Squamous Cell Carcinoma
    • Abstract: The upper aerodigestive tract is lined by a squamous epithelium. This squamous mucosa continuously regenerates from a proliferating basal layer that differentiates and eventually dies as it moves to the surface. Under this overlying squamous mucosal barrier, the tissues in different regions of the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Autoimmune Hemolytic Anemia and Red Blood Cell Autoantibodies
    • Abstract: Autoimmune hemolytic anemia (AIHA), caused by autoreactive red blood cell (RBC) antibodies along with clinical and laboratory evidence of hemolysis, is estimated to occur in approximately 1 in 80 000 patients annually.1 Although AIHA is rare, RBC autoantibodies that bind to RBCs are frequently ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • A New Immunotherapy Drug Creates a Watershed for the Surgical
           Pathologist's Role in Patient Care
    • Abstract: Advances in lung cancer therapy and the associated need for biomarker testing have enhanced the pathologist's role in the primary care of lung cancer patients. Early developments involved biomarker testing using molecular techniques to identify actionable mutations and translocations that respond ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Considerations for Conducting Meta-Analysis in Diagnostic Pathology
    • Abstract: To the Editor.-We read with great interest the recently published article entitled ''Evidence-Based Pathology: Systematic Literature Reviews as the Basis for Guidelines and Best Practices'' by Marchevsky and Wick1 and here submit the following comments concerning systematic review (SR) and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • MicroRNA-375 Suppresses Extracellular Matrix Degradation and Invadopodial
           Activity in Head and Neck Squamous Cell Carcinoma
    • Abstract: Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer worldwide with roughly 50 000 new cases and 11 000 cancer deaths in the United States every year.1 HNSCC develops in the mucosal layer of the upper aerodigestive tract. Owing to the highly invasive nature of HNSCC, it is ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Effective Biomarkers and Radiation Treatment in Head and Neck Cancer
    • Abstract: Radiation has a significant role in the management of head and neck squamous cell carcinomas (HNSCCs). Strategies to use radiation for the treatment of HNSCC have improved significantly during the past 2 decades. Radiation delivered postoperatively in the adjuvant setting significantly improves ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Honeycomb Lung: Time for a Change
    • Abstract: The current criteria for the diagnosis of idiopathic interstitial fibrosis (IPF) include a clinicoradiographic-pathologic consensus, heavily weighted toward the presence of usual interstitial pneumonitis (UIP) in the lung, or a radiographic appearance that shows high specificity for UIP. The ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Transoral Robotic Surgery in Oropharyngeal Carcinoma
    • Abstract: The management of oropharyngeal squamous cell carcinoma (OPSCCA) is the product of myriad advances in surgical, medical, and radiation oncology. This article reviews the treatment modalities for OPSCCA with a particular emphasis on the tonsillar carcinoma and will discuss treatment approaches for ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Examination of Surgical Specimens of the Esophagus
    • Abstract: Esophageal carcinoma is one of the most lethal of all of the gastrointestinal malignancies. The most frequent esophageal malignancy is adenocarcinoma, which continues to be diagnosed at a rate of 5% to 10% per year in some Western populations, in part because of the rise of Barrett esophagus and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Standards for Clinical Grade Genomic Databases
    • Abstract: Next-generation sequencing (NGS) technology is now affordable for clinical laboratories, and many are implementing NGS tests for patient care. Because of major differences in how NGS data are produced and analyzed, compared with other laboratory tests, pathologists and other laboratory ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Sensitivity and Specificity of Community Fecal Immunotesting Screening for
           Colorectal Carcinoma in a High-Risk Canadian Population
    • Abstract: Noninvasive screening tests for colorectal carcinoma include fecal occult blood tests and fecal immunochemical tests (FIT).1 Screening programs based on these tests not only are important for detecting early disease2-4 but may also be efficiently promoted by primary care physicians.5 Recent ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • The Role of High-Risk Human Papilloma Virus Testing in the Surveillance of
           Cervical Cancer after Treatment
    • Abstract: Cervical cancer is associated with persistence of high-risk (hr) human papilloma viral (HPV) infections.1 As the second most common malignancy worldwide, it is responsible for 275 000 deaths annually.2 Even though screening programs have dramatically decreased the incidence of cervical cancer, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • The Pathologist Workforce in the United States: II. an Interactive
           Modeling Tool for Analyzing Future Qualitative and Quantitative Staffing
           Demands for Services
    • Abstract: Pathologists are physicians who make diagnoses based on interpretation of tissue and cellular specimens (anatomic pathology [AP provide medical direction to clinical laboratories (laboratory medicine [LM], commonly called clinical pathology [CP and support the health care teams of institutions and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Alveolar Soft Part Sarcoma
    • Abstract: Alveolar soft part sarcoma (ASPS) is a rare neoplasm. It represents 0.2% to 0.9% of all soft tissue sarcomas1 and tends to occur between ages 15 to 35 years and is rare in patients younger than 5 years and older than 50 years.2 It is more common in females than it is in males with a 2:1 ratio. This ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Mechanisms of Invasion in Head and Neck Cancer
    • Abstract: The ability of tumors to invade into surrounding tissues is a ''hallmark of cancer''1 and is arguably the property that most greatly affects morbidity and mortality. The head and neck region is very complex, with a dense organization of fascial planes, bony and cartilaginous scaffolding, and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sun, 01 Nov 2015 00:00:00 -040
       
  • Underutilization of Meta-Analysis in Diagnostic Pathology
    • Abstract: * Context. - No studies to our knowledge have investigated citations and utilization of meta-analysis in diagnostic pathology (DP).Objective.-To characterize meta-analyses in DP compared with meta-analyses in medicine.Design.-We searched PubMed for meta-analyses in 12 major DP journals without ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Langerhans Cell Histiocytosis: A Clinicopathologic Review and Molecular
           Pathogenetic Update
    • Abstract: ^ Langerhans cell histiocytosis (LCH) comprises a wide spectrum of clinical disorders that have in common a proliferation of Langerhans-type cells with characteristic morphologic, immunophenotypic, and ultrastructural features. In part because of the diverse clinical manifestations of LCH, there ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Olmesartan-Associated Enteropathy: A Review of Clinical and Histologic
           Findings
    • Abstract: * Olmesartan is an antihypertensive medication belonging to the angiotensin II receptor blocker class of drugs that has recently been associated with severe enteropathy. Olmesartan-associated enteropathy is uncommon and may be difficult to recognize because of its clinical and histologic ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Acute Promyelocytic Leukemia: A Review and Discussion of Variant
           Translocations
    • Abstract: * The majority of patients with acute promyelocytic leukemia (APL) manifest the t(15;17)(q24.1;q21.2) translocation; however, a minor but significant proportion of patients with APL harbor complex, cryptic, or variant translocations, which typically involve RARA. With the exception of ZBTB16/RARA, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Abstracts and Case Studies from the College of American Pathologists 2015
           Annual Meeting (CAP '15)
    • Abstract: Abstract and case study poster sessions will be conducted during the 2015 College of American Pathologists Annual Meeting, which is scheduled for October 4 to 7, 2015. The meeting will take place at the Gaylord Opryland Resort and Convention Center, Nashville, Tennessee. The poster sessions will ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Metastatic Tumor Volume and Extranodal Tumor Extension: Clinical
           Significance in Patients with Stage II Breast Cancer
    • Abstract: * Context. - Lymph node status and the number of lymph node (LN) positive for cancer cells are the most important prognostic factors in breast cancer. Extranodal tumor extension (ENTE) has been used as a histopathologic feature to classify patients into high risk versus low risk for local ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Atypical Spitz Tumors: A Diagnostic Challenge
    • Abstract: * Spitzoid melanocytic lesions encompass a spectrum from benign Spitz nevi to malignant spitzoid melanomas. Spitzoid melanocytic neoplasms have significant morphologic and molecular differences from conventional melanocytic lesions, and prediction of biologic behavior and metastatic risk may be ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Marked Variability in Reported Minimal Residual Disease Lower Level of
           Detection of 4 Hematolymphoid Neoplasms: A Survey of Participants in the
           College of American Pathologists Flow Cytometry Proficiency Testing
           Program
    • Abstract: * Context. - Flow cytometry is often applied to minimal residual disease (MRD) testing in hematolymphoid neoplasia. Because flow-based MRD tests are developed in the laboratory, testing methodologies and lower levels of detection (LODs) are laboratory dependent.Objectives.-To broadly survey flow ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Abstract/Case Study Review Committee for the College of American
           Pathologists 2015 Annual Meeting
    • Abstract: The Archives of Pathology & Laboratory Medicine acknowledges the following individuals for volunteering to review abstract and case study submissions for the CAP '15 meeting.Hussam Abu-FarsakhJill AdamskiRichard AttanoosSusan C. BaerRoberto BarriosAngela N. BartleyMary Beth BeasleyAlain C. ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Morphologic Mimics of Invasive Lobular Carcinoma
    • Abstract: * Invasive lobular carcinoma of the breast is a relatively common diagnosis. However, other carcinomatous as well as noncarcinomatous neoplasms, either primary or metastatic to the breast, may mimic invasive lobular carcinoma. As treatment may differ, establishing the correct diagnosis is paramount ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Pulmonary Apical Cap-What's Old Is New Again
    • Abstract: * The pulmonary apical cap (PAC) is a morphologically distinct type of unilateral or bilateral fibroelastotic scar involving the lung apices. Despite being relatively common and having been described more than a hundred years ago, it remains underappreciated as a unique diagnostic entity by ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Assessing the Impact of Analytical Error on Perceived Disease Severity
    • Abstract: * Context. - The perception of the severity of disease from laboratory results assumes that the results are free of analytical error; however, analytical error creates a spread of results into a band and thus a range of perceived disease severity.Objective.-To assess the impact of analytical errors ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Acute Myeloid Leukemia Genetics: Risk Stratification and Implications for
           Therapy
    • Abstract: ^ Acute myeloid leukemia is a category of diseases with a common aggressive clinical presentation but with a prognosis and management that is dependent upon the underlying genetic characteristics of the neoplasm. The purpose of this brief review is to update the practicing pathologist on the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • MiT Family Translocation-Associated Renal Cell Carcinoma: A Contemporary
           Update with Emphasis on Morphologic, Immunophenotypic, and Molecular
           Mimics
    • Abstract: * Translocation-associated renal cell carcinoma (t-RCC) is a relatively uncommon subtype of renal cell carcinoma characterized by recurrent gene rearrangements involving the TFE3 or TFEB loci. TFE3 and TFEB are members of the microphthalmia transcription factor (MiT) family, which regulates ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Metastases to the Pancreas Encountered on Endoscopic Ultrasound-Guided,
           Fine-Needle Aspiration
    • Abstract: * Metastatic lesions in the pancreas are very uncommon and may be difficult to differentiate from the more commonly encountered primary neoplasms derived from the exocrine and endocrine pancreas because of the significant overlap in clinical presentation, imaging, and cytologic features. Metastasis ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Reed-Sternberg-Like Cells in Non-Hodgkin Lymphomas
    • Abstract: ^ Large atypical cells with morphologic and immunophenotypic features resembling Reed-Sternberg cells can be seen in the background of reactive lymphadenopathies as well as non-Hodgkin lymphomas. The presence of these cells is an important diagnostic pitfall that must be recognized by pathologists ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Intraductal Carcinoma of the Prostate: Morphologic Features, Differential
           Diagnoses, Significance, and Reporting Practices
    • Abstract: * The differential diagnosis for atypical cribriform lesions of the prostate has become increasingly complex and includes intraductal carcinoma of the prostate, high-grade prostatic intraepithelial neoplasia, and atypical intraductal proliferations. In this review, we summarize the morphologic and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Safety Assurance Factors for Electronic Health Record Resilience (SAFER)
           Guidelines
    • Abstract: To the Editor.-We read with interest the Special Section in the March 2015 issue of the ARCHIVES about ''Empowering Pathology in the Era of the Electronic Health Record comprising 5 articles commissioned by the Diagnostic Intelligence and Health Information Technology Committee of the College of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • The World Health Organization Classification of Skeletal Muscle Tumors in
           Pediatric Rhabdomyosarcoma: A Report from the Children's Oncology Group
    • Abstract: * Context. - Since 1995, the International Classification of Rhabdomyosarcoma has provided prognostically relevant classification for rhabdomyosarcoma (RMS) and allowed risk stratification for children with RMS. The International Classification of Rhabdomyosarcoma includes botryoid and spindle cell ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Advanced Companion Diagnostics Facilities: Opportunity Favors the Prepared
           Laboratory
    • Abstract: To the Editor.-It is with great interest that we read the recent editorial by Drs Khoury and Catenacci.1 As pathologists working in a College of American Pathologists (CAP)-accredited laboratory that specializes in supporting clinical trials (including those that require an investigational device ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Template for Reporting Results of Biomarker Testing of Specimens from
           Patients with Gastrointestinal Stromal Tumors
    • Abstract: The College of American Pathologists offers these templates to assist pathologists in providing clinically useful and relevant information when reporting results of biomarker testing. The College regards the reporting elements in the templates as important elements of the biomarker test report, but ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Thu, 01 Oct 2015 00:00:00 -040
       
  • Assessing Clinical Laboratory Quality: A College of American Pathologists
           Q-Probes Study of Prothrombin Time INR Structures, Processes, and Outcomes
           in 98 Laboratories
    • Abstract: In 2011, two million patientswereinjuredseriously inthe United States by prescription drug therapy, ultimately resulting in 128 000 patient deaths.1 A 2013 report summarizing patient drug safety issues found that the anticoagulation drugs dabigatran and warfarin were the 2 drugs most frequently ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Template for Reporting Results of Biomarker Testing of Specimens from
           Patients with Tumors of the Central Nervous System
    • Abstract: The College of American Pathologists offers these templates to assist pathologists in providing clinically useful and relevant information when reporting results of biomarker testing. The College regards the reporting elements in the templates as important elements of the biomarker test report, but ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Decreased Clinical Laboratory Turnaround Time after Implementation of a
           Collection Manager System
    • Abstract: To the Editor.-Patient safety and specimen analysis turnaround time are of utmost importance in the clinical laboratory of a busy tertiary care hospital. Many institutions have employed lean and Six Sigma strategies to improve these metrics.1-3 At our institution, a 635-bed hospital with an average ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • A Brief Review and Update of the Clinicopathologic Diagnosis of
           Arrhythmogenic Cardiomyopathy
    • Abstract: Arrhythmogenic cardiomyopathy (AC) is a primarily autosomal-dominant cardiomyopathy resulting from defects of desmosomal proteins that would normally provide structural integrity to cardiomyocytes.1 The incidence is frequently cited as 1 in 5000, but it is arguably greater than 1 per 1000 if mild ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Primary Anal Canal Syphilis in Men: The Clinicopathologic Spectrum of an
           Easily Overlooked Diagnosis
    • Abstract: While rates of primary and secondary syphilis in the United States reached a low in the 1990s and 2000,1 there has been a steady increase of syphilis in the male population since 2001, particularly in men who are human immunodeficiency virus (HIV) positive (HIVþ) and men who have sex with men ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Malignant (Diffuse) Mesothelioma in Patients with Hematologic
           Malignancies: A Clinicopathologic Study of 45 Cases
    • Abstract: Malignant mesothelioma is a universally fatal malignancy with most cases attributable to prior asbestos exposure.1 A number of case reports have suggested a relationship between asbestos exposure and hematologic malignancies, including non-Hodgkin lymphoma, leukemia, and multiple ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Primary Bone Tumors: Epidemiologic Comparison of 9200 Patients Treated at
           Beijing Ji Shui Tan Hospital, Beijing, China, with 10 165 Patients at Mayo
           Clinic, Rochester, Minnesota
    • Abstract: Worldwide, cancer is the second leading cause of death, following heart disease, accounting for 23% of all deaths.1 Although most cancers causing death are carcinomas of lung, prostate, and breast, primary malignancy of the bone and joints is ranked as the third leading cause of death in patients ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Advocating Nonsurgical Management of Patients with Small, Incidental
           Radial Scars at the Time of Needle Core Biopsy: A Study of 77 Cases
    • Abstract: Radial scars of the breast are benign sclerosing lesions commonly found as incidental microscopic findings in surgical excision specimens. These reactive proliferations are associated with a slight increase in risk for the development of subsequent breast cancer, similar to that of proliferative ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Rhesus Immune Globulin Dosing in the Obesity Epidemic Era
    • Abstract: To the Editor.-Rhesus immune globulin (RhIG) has been licensed in the United States since 1968 and has dramatically reduced the incidence of Rh (D) alloimmunization from 16% to less than 0.1%.1 Because as little as 0.1 mL of Dþ erythrocytes can result in alloimmunization,1 adequate dosing of RhIG ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Hepatosplenic T-Cell Lymphoma: A Clinicopathologic Review with an Emphasis
           on Diagnostic Differentiation from Other T-Cell/Natural Killer-Cell
           Neoplasms
    • Abstract: Hepatosplenic T-cell lymphoma (HSTL) is an aggressive T-cell lymphoma that accounts for less than 1% of non-Hodgkin lymphoma and about 3% of all T-cell lymphomas/leukemias.1 It is characterized by a primary extranodal involvement of medium-sized lymphoid cells, typically with sinusoidal ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Keratin Expression Patterns in Stromal Cells of Benign Sclerosing Lesions
           of the Breast: A Potential Diagnostic Pitfall
    • Abstract: Metaplastic carcinomas arising in association with benign sclerosing lesions are rare lesions in which a neoplastic spindle cell proliferation with varying degrees of cytologic atypia can be recognized extending beyond the boundaries of the complex sclerosing lesion or papilloma.1,2 However, in ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Molecular Testing in Anatomic Pathology and Adherence to Guidelines: A
           College of American Pathologists Q-Probes Study of 2230 Testing Events
           Reported by 26 Institutions
    • Abstract: With the rapid growth of specialized ancillary testing, laboratories are frequently asked to use anatomic pathology material to perform molecular testing. Such testing may be conducted either in-house or as a send-out to a reference laboratory, and the testing may be quite costly. In some cases, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Practical Applications in Immunohistochemistry: Evaluation of Diffuse
           Large B-Cell Lymphoma and Related Large B-Cell Lymphomas
    • Abstract: Diffuse large B-cell lymphoma (DLBCL) is one of the most common diagnoses in hematopathology, typically including approximately 30% to 40% of non-Hodgkin lymphoma cases. In spite of being a common diagnosis, it represents a heterogeneous group of disorders that are related by the identification of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • A Call to Standardize Preanalytic Data Elements for Biospecimens, Part II
    • Abstract: The College of American Pathologists (CAP) is committed to helping pathologists and the medical specialty of pathology successfully implement genomically informed, personalized precision health care. As part of this mission, the CAP published a practical resource for community pathologists.1 This ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Tue, 01 Sep 2015 00:00:00 -040
       
  • Sclerosing Thymoma
    • Abstract: Although thymomas account for about 20% of mediastinal neoplasms and are the most-common anterior mediastinal neoplasm,1 the overall incidence of thymomas is rare. Here. we present an extremely rare variant of thymomas, the so-called sclerosing thymomas. First reported in 1994 by Kuo2 only a ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Development and Evaluation of a Logical Delta Check for Identifying
           Erroneous Blood Count Results in a Tertiary Care Hospital
    • Abstract: Mislabeled laboratory specimens have the potential to lead to adverse patient outcomes through misdiagnosis, delayed treatment, and inappropriate treatment. For this reason, The Joint Commission, formerly The Joint Commission on Accreditation of Healthcare Organizations, has listed ''Improve the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Interstitial Lung Diseases That Are Difficult to Classify: A Review of
           Bronchiolocentric Interstitial Lung Disease
    • Abstract: The spectrum of disorders included in the category of idiopathic interstitial lung disease is vast and complex. How to separate and classify these disorders become a perplexing problem because the various disorders could be categorized in a variety of ways: diffuse or localized; predominant ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Standardized Molecular Monitoring for Variant BCR-ABL1 Transcripts in
           Chronic Myeloid Leukemia
    • Abstract: To the Editor.-Molecular monitoring of the BCR-ABL1 fusion gene transcripts in response to tyrosine kinase inhibitor (TKI) therapy, achieved by relative quantitative polymerase chain reaction (RQ-PCR), is an essential part of the modern management of chronic myeloid leukemia (CML). Efforts to ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • The So-Called Short-Fiber Controversy: Literature Review and Critical
           Analysis
    • Abstract: Early on during studies of experimental animals exposed by inhalation to asbestos fibers, it was recognized that fiber length was a determining factor in pathogenicity. Vorwald et al1 concluded that fibrogenicity of chrysotile asbestos was related to fibers 20 lm or greater in length. The authors ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • The Processing of Surgical Specimens with Forensic Evidence: Lessons
           Learned from the Boston Marathon Bombings
    • Abstract: On April 15, 2013, 2 pressure-cooker type bombs detonated near the Boston Marathon finish line, killing 3 people and injuring an estimated additional 264 people.1 The bombing victims were treated at the Boston, Massachusetts area's 6 major trauma centers and other local hospitals for a multitude of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Acid-Fast Smear and Histopathology Results Provide Guidance for the
           Appropriate Use of Broad-Range Polymerase Chain Reaction and Sequencing
           for Mycobacteria
    • Abstract: Selection of the optimum tests for a specimen becomes more challenging as newer testing methods become increasingly available for the detection of microorganisms. Polymerase chain reaction (PCR)-based methods for microorganism detection and identification are attractive given the sensitivity and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Brief Updates in Lung Pathology
    • Abstract: This issue of the Archives of Pathology & Laboratory Medicine brings another installment of the ongoing series titled Top Stories in Anatomic Pathology. Previous editions of Top Stories have presented views and opinions of the faculty of the Department of Pathology at the University of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Performance Characteristics of Urinary Tract Cytology: Observations from
           the College of American Pathologists Interlaboratory Comparison Program in
           Nongynecologic Cytopathology
    • Abstract: The earliest attempts at microscopic evaluation of urinary samples date back to the mid-19th century, when Sanders1 and Lambl2 independently described abnormal cells in urinary specimens. In the mid-1940s, urinary cytology became an established means to evaluate the urinary tract through the work ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Changes of Ischemia-Modified Albumin during the Postoperative Period in
           Patients with Colorectal Surgery
    • Abstract: To the Editor.-Albumin is a crucial protein with many functions, and serum albumin decreases in cases of critical pathologies.1 The albumin (an N-terminal region) is modified by oxidative stress, called ischemia-modified albumin (IMA), a dysfunctional form of albumin.2 Higher IMA levels are ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Smoking-Related "Interstitial" Lung Disease
    • Abstract: Human lung tissue responds to injury with a combination of destruction, remodeling, and repair that is manifest by airspace enlargement and laying down of collagen and elastin.1,2 The process of remodeling and repair has been well documented as a response to the inflammation and destruction from ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Malignant Mesothelioma Diagnosis
    • Abstract: The diagnosis of malignant mesothelioma continues to be challenging. There are several aspects that have recently been addressed by consensus by pathologists with expertise in the subject.1 Several recent articles2-5 have provided much needed data on histologic variants and light microscopic ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Comes Digital Pathology
    • Abstract: One year ago, it was predicted that the US Food and Drug Administration (FDA) was likely to approve whole slide imaging (WSI) for digital pathology ''within the next few months1 Get ready. Digital pathology will soon be the glass slide's diagnostic companion. On February 25, 2015, the FDA issued ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • American Society of Clinical Oncology/College of American Pathologists
           Human Epidermal Growth Factor Receptor 2 Testing Clinical Practice
           Guideline Upcoming Modifications: Proof That Clinical Practice Guidelines
           Are Living Documents
    • Abstract: Recently, the Journal of Clinical Oncology ( JCO ) received a letter to the editor from Rakha et al1 about the American Society of Clinical Oncology (ASCO)/College of American Pathologists (CAP) Recommendations for Human Epidermal Growth Factor Receptor 2 (HER2) Testing in Breast Cancer Clinical ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Levamisole-Induced Vasculitis: A Characteristic Cutaneous Vasculitis
           Associated with Levamisole-Adulterated Cocaine
    • Abstract: Levamisole is a veterinary antihelminthic drug that, in the past, was a US Food and Drug Administration-approved drug in humans used to treat various cancers and rheumatoid arthritis because of its immunomodulating effects.1,2 The Food and Drug Administration banned the use of levamisole in the ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Classification of Psammoma Bodies in the Revised College of American
           Pathologists Thyroid Cancer Protocol/In Reply
    • Abstract: To the Editor.-We read with great interest the revised College of American Pathologists (CAP) thyroid cancer protocol that was published in August of 2014.1 Many of the updates add clarity to the 2012 version of the document as well as incorporate new information. However, one point of concern is ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • The Cancer Genomics Resource List 2014
    • Abstract: The last 10 years have seen a transformation in genomic medicine and its application to cancer research and clinical care.1,2 Comprehensive sequencing efforts have identified at least 140 genes that are somatically mutated in cancer,3 some of which can promote or drive tumorigenesis. In several ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Introducing 3-Dimensional Printing of a Human Anatomic Pathology Specimen:
           Potential Benefits for Undergraduate and Postgraduate Education and
           Anatomic Pathology Practice
    • Abstract: Three-dimensional (3D) printing technology is a safe and affordable technique capable of producing 3D physical models of factual objects or constructed designs. It creates a 3D model of objects with realistic representation of depth, shape, and texture, producing a sharp, precise copy of portrayed ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Practices for Identifying and Rejecting Hemolyzed Specimens Are Highly
           Variable in Clinical Laboratories
    • Abstract: Hemolysis is the disruption of the blood cell membranes, with the release of the cell contents and membrane fragments into the surrounding fluid. Unfortunately, in most clinical laboratories, hemolysis interferes with a variety of measurements made on analytes occurring in patient specimens, making ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • The Demise of the Term Bronchioloalveolar Carcinoma
    • Abstract: In the mid-1920s, Edmund Vincent Cowdry, esteemed physician of Cowdry type A and type B inclusion bodies fame, among other entities, published 3 articles about jaagsiekte (from Afrikaans, meaning driving or chasing sickness) and progressive pneumonia in American and South African sheep, in which he ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Erratum
    • Abstract: The article titled Practical Applications in Immunohistochemistry: Evaluation of Diffuse Large B-Cell Lymphoma and Related Large B-Cell Lymphomas (O'Malley DP, Auerbach A, Weiss LM; Arch Pathol Lab Med. 2015 [published online ahead of print January 2, 2015]; doi:10.5858/arpa. 2014-0451-CP) contains ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Sat, 01 Aug 2015 00:00:00 -040
       
  • Sex Differences in Workplace Satisfaction and Engagement of Academic
           Pathologists: Opportunities to Enhance Faculty Diversity
    • Abstract: * Context.-There is attrition of women across professorial ranks in academic pathology. Women are underrepresented as leaders; 15.4% of academic pathology departments are chaired by women, according to the Association of American Medical Colleges (AAMC).Objective.-To identify areas for targeted ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Clinicopathologic Correlates of Primary Aldosteronism
    • Abstract: * Primary aldosteronism is the most common cause of secondary hypertension, incurring significant cardiovascular morbidity and mortality. Our understanding of this disease has evolved substantially during the past decade. Recently, the molecular basis of primary aldosteronism has begun to be ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Performance in Measurement of Serum Cystatin C by Laboratories
           Participating in the College of American Pathologists 2014 CYS Survey
    • Abstract: ^ Context. - Cystatin C is becoming an increasingly popular biomarker for estimating glomerular filtration rate, and accurate measurements of cystatin C concentrations are necessary for accurate estimates of glomerular filtration rate.Objective.-To assess the accuracy of cystatin C concentration ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Design of a Genomics Curriculum: Competencies for Practicing Pathologists
    • Abstract: * Context. - The field of genomics is rapidly impacting medical care across specialties. To help guide test utilization and interpretation, pathologists must be knowledgeable about genomic techniques and their clinical utility. The technology allowing timely generation of genomic data is relatively ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Calcifying Fibrous Tumor of the Gastrointestinal Tract
    • Abstract: * Calcifying fibrous tumor is a benign mass lesion classically described as a softtissue tumor. However, a thorough review of the literature reveals that it can occur virtually anywhere, including the tubular gastrointestinal (GI) tract. Its clinical manifestations are variable in the GI tract, and ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Hepatic Granulomas: A Review with Emphasis on Infectious Causes
    • Abstract: Context.-Many diseases that cause granulomas or granulomatous inflammation involve the liver. Some of these disease processes are intrinsic hepatic diseases, whereas others are disseminated systemic diseases that involve the liver as well as other organs.Objective.-To review the evaluation of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Sentinel Node Biopsy after Neoadjuvant Chemotherapy: Prechemotherapy Nodal
           Status Is Crucial for Test Performance/In Reply
    • Abstract: To the Editor.-We read with interest the publication by Elliott et al1 about sentinel node biopsy (SNB) after neoadjuvant chemotherapy (NAC). Sentinel node biopsy predicts axillary status, with negative predictive value around 95% in patients with cT1-T2 cN0 breast cancer. In the NAC scenario, ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
  • Clinical Laboratory Quality Practices When Hemolysis Occurs
    • Abstract: * Context. - Hemolyzed specimens delay clinical laboratory results, proliferate unnecessary testing, complicate physician decisions, injure patients indirectly, and increase health care costs.Objective.-To determine quality improvement practices when hemolysis occurs.Design.-We used the College of ... (Publication: Archives of Pathology & Laboratory Medicine)
      PubDate: Wed, 01 Jul 2015 00:00:00 -040
       
 
 
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