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     ISSN (Print) 1082-801X
     Published by Advanstar Communications, Inc. Homepage  [9 journals]   [SJR: 0.112]   [H-I: 11]
  • Strep Throat Risk Score Brings Together Patient Data and Big Data to
           Potentially Reduce Unnecessary Doctors' Visits
    • Abstract: A new risk measure called a "home score" could potentially prevent 230,000 trips to US doctors' offices every year for suspected strep throat, according to a study online in Annals of Internal Medicine.The score combines patients' symptoms and demographic information with data on local strep throat ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Minimize Risk of Healthcare-Associated Infections in Critical Care
           Environments with Best Practices
    • Abstract: Healthcare-associated infections (HAIs) are less likely to occur in favorable critical care work environments, said a study in the American Journal of Critical Care.The study found nurses working in favorable critical care environments were about 40% less likely to report that HAIs, including ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • High-Dose Isotretinoin Reduces Risk of Acne Vulgaris Relapse
    • Abstract: Higher doses of isotretinoin can effectively treat patients with acne vulgaris and reduce the relapse rate without significant increased adverse events, according to a recent report published in JAMA Dermatology.Rachel C. Blasiak, MD, MPH, and her colleagues from the department of dermatology, ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Depression in the Elderly: A Pharmacist's Perspective
    • Abstract: PEER-REVIEWEDAbstractDepression is a disease state that is commonly underdiagnosed and undertreated in patients over the age of 65 years. Elderly patients may differ from younger patients in the presentation of symptoms and in the prevalence of comorbidities. Risk factors for the development of ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Warnings on Kids' Cold Products Slashed ER Visits
    • Abstract: FROM THE LITERATUREfrom. Staff ReportsAfter manufacturers began printing new warnings on medicine bottles, a smaller percentage of emergency room (ER) visits resulted from children taking cold and cough products, according to a study in Pediatrics.Drug-makers voluntarily recalled over-the-counter ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Collaborative Care to Boost Medication Adherence May Not Improve Outcomes
           Significantly
    • Abstract: Collaborative care with pharmacists helped to boost medication adherence in patients with acute coronary syndrome (ACS) after hospital discharge. However, after 12- month follow-up, the proportion of patients who achieved blood pressure and LDL-cholesterol goals were not significantly different ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Studies: Lurasidone Effective for Treating Depression Associated with
           Bipolar Disorder
    • Abstract: Lurasidone HC1 (Latuda) reduces depressive symptoms in adult patients with bipolar depression when used as monotherapy and adjunctive therapy to lithium or valproate. This flexibility is important given the multiple unmet needs of patients with bipolar depression, according to two phase 3 studies ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • New Molecular Entity
    • Abstract: TivicayDolutegravirGLAXOSMITHKLINEAn integrase strand transfer inhibitor for treatment of HIV 1 infection in adults and pediatric patients aged 12 years and older and weighing at least 40 kilograms, as part of combination antiretroviral therapy.FDA approved dolutegravir (Tivicay, GlaxoSmithKline) ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • FDA Actions in Brief
    • Abstract: Luliconazole (Luzu Cream, 1%, Valeant Pharmaceuticals) was approved for the 1-week, once-daily treatment of interdigital tinea pedis, tinea cruris, and tinea corporis, caused by the organisms Trichophyton rubrum and Epidermophyton floccosum, in patients aged 18 years and older.Ibrutinib (Imbruvica, ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Long-Term Oral Contraceptive Users at Risk for Glaucoma
    • Abstract: Women using oral contraceptives for 3 years or more may be at risk for developing glaucoma and should be screened for the eye disease if they have additional risk factors, according to researchers at the American Academy of Ophthalmology annual meeting in New Orleans.Shan C. Lin, MD, the lead ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Chemotherapy Outpatients May Benefit from Blood-Thinners to Prevent VTE:
           Study
    • Abstract: Outpatients receiving chemotherapy are at high risk of developing venous thromboembolism (VTE) and of major bleeding complications, especially those with pancreas, stomach and lung cancer, according to a study published online in The Oncologist. Therefore thromboprophylaxis, or blood thinning ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Alzheimer's Research: Now Is the Time for Advocates to Unite
    • Abstract: A dozen promising trials of Alzheimer's disease could be launched today, if funds were available, said Paul Aisen, MD, director of the Alzheimer's Disease Cooperative Study at the University of California, San Diego. "We know how to pick the drugs. We even know what designs we would use for the ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Pipeline Preview
    • Abstract: Complete response* Cariprazine (Forest Laboratories and Gedeon Richter Pic) an atypical antipsychotic for the treatment of schizophrenia and for the acute treatment of manic or mixed episodes associated with bipolar I disorder in adults. In the complete response letter, FDA acknowledged that ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Focus on Tapentadol: Role in the Treatment of Neuropathic Pain
    • Abstract: AbstractNeuropathic pain is a difficult-to-treat condition; pathologic changes in neuronal pathways may result in suboptimal analgesic control with opioid agents alone. Polypharmacy is employed often to simultaneously target multiple levels of the pain pathway, at the expense of escalated ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Statins May Lower Prostate Cancer-Related Mortality Risk
    • Abstract: from Staff ReportsPatients with prostate cancer who use statins may have a lower risk of death from their disease, according to a study published online ahead of print in the Journal of Clinical Oncology.Using large population-based databases from the United Kingdom, Canadian researchers assembled ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Analgesic Overuse Can Exacerbate Chronic Post-Traumatic Headaches in
           Adolescent Concussion Patients
    • Abstract: from Staff ReportsExcessive analgesics use can contribute to the chronic headache associated with concussion in some adolescent patients and discontinuing these drugs can improve symptoms, according to researchers at the 42nd Annual Meeting of the Child Neurology Society, in Austin, Texas.In a ... (Publication: Formulary)
      PubDate: Sun, 01 Dec 2013 00:00:00 -050
       
  • Specialty Pharmaceuticals: Transparency, Collaboration for Improving Drug
           and Diagnosis Coding on Medical Claims
    • Abstract: AbstractAccording to an industry survey conducted earlier this year by PhRMA, more than 900 medicines and vaccines have been identified in various stages of development. To keep pace, the strategies that were adequate for the 'empty pipeline' scenarios of a few years ago-to code each agent, ... (Publication: Formulary)
      PubDate: Fri, 01 Nov 2013 00:00:00 -040
       
  • Study Highlights Need to Address Anaphylaxis Prevention
    • Abstract: WHAT'S NEW IN DRUG RESEARCH AND MANAGED CARE PHARMACYSevere life-threatening allergic reactions are more common than many thought. Anaphylaxis very likely occurs in nearly 1 in 50 Americans (1.6 and the rate is probably higher, close to 1 in 20 (5.1 according to a study published in the Journal of ... (Publication: Formulary)
      PubDate: Fri, 01 Nov 2013 00:00:00 -040
       
  • Emerging Therapies for Treating Type 2 Diabetes
    • Abstract: AbstractType 2 diabetes mellitus presents multiple treatment dilemmas for prescribers and healthcare clinicians. The number of oral agents for treating diabetes has increased over the past decade, and the best treatment regimen for each patient often varies based on comorbid conditions and ... (Publication: Formulary)
      PubDate: Fri, 01 Nov 2013 00:00:00 -040
       
  • Off-Label Use of Atypical Antipsychotics: Lack of Evidence for Their Use
           in Primary Insomnia
    • Abstract: PEER REVIEWEDAbstractAtypical antipsychotics are some of the most commonly prescribed psychotropic medications in the United States. There is increasing off-label use despite lack of evidence to support it in some of these medical or psychiatric conditions. One of these growing uses is for the ... (Publication: Formulary)
      PubDate: Fri, 01 Nov 2013 00:00:00 -040
       
  • Sunscreen Recommendation Rates Low
    • Abstract: Physicians discussed sunscreen use with patients at less than 1% of visits, according to recent study results.Overall, healthcare practitioners mentioned sunscreen use at approximately 12.83 million visits (0.07 In visits with patients with a skin disease diagnosis, sunscreen use was reportedly ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Cognitive Enhancers Don't Help after 96 Weeks in Mild Cognitive Impairment
           for Alzheimer's Patients
    • Abstract: Cognitive enhancers-drugs taken to enhance concentration, memory, alertness, and moods- that are often given to patients with Alzheimer's disease do not improve cognition or function for those with mild cognitive impairment (MCI) in the long term-about 96 weeks, according to a study published ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • For Children, Skipped Medications Often Lead to Emergency Department
           Visits
    • Abstract: Poor medication adherence causes more frequent hospitalizations and emergency department (ED) visits among children and adolescents who have a chronic medical condition, such as asthma and type 1 diabetes, according to a study recently published in Pediatrics.Lead author Meghan McGrady, PhD, of the ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Kaiser Permanente's Large-Scale Hypertension Program Nearly Doubles BP
           Control Rates
    • Abstract: Kaiser Permanente (KP) Northern California nearly doubled the rate of blood pressure control among adult members with diagnosed hypertension between 2001 and 2009 through a large-scale community-based program, the Journal of the American Medical Association reported recently.In 2001, lead author ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Will Crowdfunding and General Solicitation Spur Orphan Drug Development
           for Biotechs'
    • Abstract: Ever since the passage of the Orphan Drug Act (ODA) 30 years ago, more than 350 orphan drugs have been developed to help treat patients with rare diseases. FDA has provided many incentives to biotech companies-such as shorter clinical trials, longer patent times, and tax breaks-making it an ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • CDC Seeks Answers on E-Cigarettes
    • Abstract: About half of the 45 million Americans who smoke cigarettes try to quit each year, according to the Centers for Disease Control and Prevention (CDC). One of the ways to attempt quitting is to use a substitute such as nicotine gum or the electronic cigarette, which is rising in popularity.Electronic ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Location Helps Determine Access to Affordable, Quality Healthcare for
           Americans
    • Abstract: For healthcare consumers, low household income need not condemn them to low quality, but high income is not the panacea either. A state scorecard released in September by the Commonwealth Fund indicated that the wide differences in healthcare experiences found in a state-by-state comparison often ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Antibiotic Formulary Guidelines for Health Systems: Balancing Evidence and
           Stewardship
    • Abstract: PEER-REVIEWEDAbstractFew antibiotics are expected to enter the market in the near future, therefore health systems must routinely optimize their available armamentarium of antibiotics. Antibiogram data provide helpful information on acceptable empiric treatment strategies and whether adjustments ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Infant Motrin Recalled Because of Possible Contamination
    • Abstract: FROM THE LITERATUREfrom. Staff ReportsThe McNeil Consumer Healthcare Division of Johnson & Johnson (J&J) last month recalled 3 lots-approximately 200,000 bottles-of Motrin Infants' formula because of possible contamination with specks of plastic.The company asked retailers to remove the affected ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Clear Marking on Pain Patches Required by FDA
    • Abstract: from Staff ReportsFDA is requiring color changes to the printing on fentanyl (Duragesic) pain patches so that it is clearly visible, to help avoid risk of accidental exposure. Accidental exposure to these patches that contain a narcotic opioid can cause serious harm and death in children, pets, and ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Reducing Adverse Drug Events by Targeting At-Risk Patients
    • Abstract: Knowing which patients are most at-risk for adverse drug events would help hospitals direct pharmacist-led counseling services to those who need it the most. The American Society of Health-System Pharmacists (ASHP) Foundation is funding research it believes will make it easier to identify those ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • One Quarter of Heart Disease Deaths Are Preventable
    • Abstract: from Staff ReportsAt least one quarter of the 800,000 deaths annually attributed to cardiovascular disease could be prevented if people stopped smoking, reduced salt intake, and adopted other healthy habits, according to a report by the US Centers for Disease Control and Prevention (CDC).Heart ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Some Opioids Linked to Certain Birth Defects
    • Abstract: Women taking opioids just before or during early pregnancy are 2 times more likely to have a pregnancy affected by a neural tube defect, such as spina bifida, according to a study published online September 9 in Obstetrics & Gynecology in advance of the October 2013 print issue."We found that use ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Mental 'Fogginess' with Tamoxifen Use Should Be Taken Seriously
    • Abstract: Tamoxifen use among some women with breast cancer has been reported to cause mental "fogginess" while on the medication, and researchers have demonstrated that the side effect is real, according to an online study published September 17 in the Journal of Neuroscience.Tamoxifen, one of the most ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Varenicline May Help Some Patients with Depression Quit Smoking
    • Abstract: from Staff ReportsAbout half of smokers seeking treatment for smoking cessation have a history of depression. Compared with smokers who are not depressed, those who suffer from a major depressive disorder (MDD) have greater difficulty quitting, according to a study published September 17 in the ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • New Formulation
    • Abstract: SitavigAcyclovir mucoadhesive buccal tabletsBIOALLIANCE PHARMAA mucoadhesive buccal tablet containing 50 mg of acyclovir for the treatment of recurrent herpes labialis (cold sores) in immunocompetent adultsIn April 2013, FDA approved acyclovir (Sitavig, BioAlliance Pharma) mucoadhesive buccal ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Better Adherence, Lower Healthcare Costs for Diabetes Patients Enrolled in
           Value-Based Insurance Designs
    • Abstract: A recent study, coordinated by the Florida Health Care Coalition (FHCC), with primary analysis conducted by Truven Health Analytics, expands the current research efforts on value-based insurance design. FHCC is a non-profit group of employers from Florida representing nearly 2 million covered ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Children Who Miss Vaccinations at Increased Risk for Whooping Cough
    • Abstract: from. Staff ReportsChildren who miss diphtheria, tetanus toxoid, and acellular pertussis (DTaP) vaccine doses are more likely to develop whooping cough, according to a study in JAMA Pediatrics.Jason Glanz, PhD, of Kaiser Permanente Colorado, and colleagues studied the correlation between ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Concerns about Effectiveness of Preservative Lead to Recall of Dry-Eye
           Solution
    • Abstract: from Staff ReportsAltaire Pharmaceuticals is voluntarily recalling a total of 9 lots of carboxymethylcellulose sodium 0.5% ophthalmic solution, 30 mL, at the consumer level. No adverse effects to consumers have been reported, but complaints of mold found in the 30-mL bottles after use raised ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Oral Oncolytics Part 2: Assessing the Value of Newer Agents versus Current
           Standards of Care as Part of P&T Processes
    • Abstract: AbstractPart 1 focused on comparing newer oral oncolytics to older ones in chronic myelogenous leukemia, advanced kidney cancer, medullary thyroid cancer, and metastatic melanoma. Part 2 focuses on comparing newer oral chemotherapies to current intravenous (IV) chemotherapy. There are several ... (Publication: Formulary)
      PubDate: Tue, 01 Oct 2013 00:00:00 -040
       
  • Catamaran Anticipates New Advantages with Recent PBM Acquisitions
    • Abstract: Catamaran, a pharmacy benefits manager (PBM) has been on a buying binge since 2008, snapping up its sixth PBM, Restât. The $409.5 million cash purchase is expected to close in the fourth quarter of 2013."Restât will be the first PBM we have acquired that is not a current client," said Tony Perkins, ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Many US Neurologists May Be Ignorant of Serious Epilepsy Drug Side Effects
    • Abstract: FROM THE LITERATUREOne-fifth of US neurologists appear unaware of serious drug safety risks associated with various antiepilepsy drugs, according to a study published online in Epilepsy and Behavior.The findings suggest that FDA needs a better way to communicate information to specialists about ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Canadian Medical Association Finds Expanded Pharmacist Functions
           Beneficial
    • Abstract: Pharmacists in Canada were recently given broader responsibilities including, in certain provinces, prescribing privileges, vaccination abilities, and the ability to order and interpret laboratory tests. This newly expanded role for Canadian pharmacists can benefit both patients and physicians, ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Heavy Coffee Consumption May Endanger Health in Adults Younger Than 55
    • Abstract: Drinking more than 28 cups of coffee per week may be unhealthy for people younger than 55, according to a recent study published in Mayo Clinic Proceedings.A multicenter research team, including Carl J. Lavie, MD, of the Ochsner Medical Center, New Orleans, investigated the effect of coffee ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • FDA Issues Neuropathy Warning on Fluoroquinolones
    • Abstract: FROM THE LITERATUREfrom Staff ReportsDrug labels and Medication Guides for all fluoroquinolone antibacterial drugs should be updated to better describe the serious side effect of peripheral neuropathy, a nerve disorder occurring in the arms or legs, according to an FDA Drug Safety Communication. ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Broader-Spectrum Antibiotics Overprescribed in Ambulatory Settings
    • Abstract: The majority of antibiotics prescribed for adults in ambulatory care settings are broad-spectrum agents, most commonly fluoroquinolones and macrolides. These are frequently prescribed for conditions where no antibiotic therapy is needed at all, such as for bronchitis and colds, which are caused by ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • The Risk of Guillain-Barré Syndrome after Influenza Vaccination
    • Abstract: FROM THE LITERATUREGuillain-Barré syndrome (GBS) is an immune-mediated flaccid paralysis that can range from muscle weakness and tingling to respiratory paralysis requiring prolonged respiratory support and ventilation. Overall, GBS is a rare disease, with annual incidence averaging 1 to 2 cases ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • ACOs Prompt P&T Committees to Rethink Medication Analysis to Support
           Contractual Arrangements
    • Abstract: Accountable care organizations (ACOs) are groups of doctors, hospitals, and other healthcare providers, who come together voluntarily to give coordinated high-quality care to the patients they serve. Coordinated care helps ensure that patients, especially the chronically ill, get the right care at ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Real-World Performance Becomes Payers' Key Metric in Drug Selection
    • Abstract: Drug evaluation and selection models are changing. Safety and efficacy have become the starting point for consideration by many payers. What today's payers really want to see, however, is evidence of superior performance in real world patient populations."We have heard from managed care executives ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • At Least 1 in 10 Americans Have Taken Another's Rx
    • Abstract: At least 1 in 10 Americans admit taking someone else's prescription drug, according to an ongoing Reuters/psos online survey. About a quarter of those people used the prescription drugs to get high, according to the survey.While nearly 75% of those surveyed said they have never taken a prescription ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Naltrexone Plus Prolonged Exposure Therapy Helps Alcohol-Dependent PTSD
           Patients
    • Abstract: In a study of patients with alcohol dependence and post-traumatic stress disorder (PTSD), treatment with naltrexone resulted in a decrease in the percentage of patient drinking days. Prolonged exposure therapy was not associated with an exacerbation of alcoholuse disorder.Lead author Edna B. Foa, ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Pilot Program Explores Use of 2D Barcodes in Vaccine Record-Keeping
    • Abstract: In an effort to help facilitate accurate and uniform records of US vaccine usage, the Centers for Disease Control and Prevention (CDC) and immunization community stakeholders are exploring the potential of 2-dimensional (2D) barcoding to streamline immunization practices.The 2D vaccine pilot ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Brinzolamide-Brimonidine May Benefit Patients Who Have Contraindications
           to Beta-Blocker
    • Abstract: The new fixed-combination of brinzolamide 1% plus brimonidine 0.2% (Simbrinza Suspension, Alcon Laboratories) is a safe and effective option for lowering intraocular pressure (IOP) in patients with glaucoma or ocular hypertension uncontrolled on monotherapy.The medication also brings the benefits ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Health Insurance Exchange Formularies: Charting New Waters in the World of
           Formulary
    • Abstract: PEER-REVIEWEDAbstractNew regulations in the Patient Protection and Affordable Care Act have led to the birth of essential health benefits. The Centers for Medicare and Medicaid Services' (CMS) new division, the Center for Consumer Information and Insurance Oversight (CCIIO), is responsible for the ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Recognizing Pharmacists as Healthcare Providers-A Solution for the Patient
           Protection and Affordable Care Act Roll-Out
    • Abstract: AbstractThe Patient Protection and Affordable Care Act includes availability of preventive care services covering immunizations, wellness visits, and access to primaiy care. Four of 5 patients who visit a medical provider leave with at least 1 prescription. Though medications rank as the number one ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Insulin Pumps Outperform Injections in Diabetic Children
    • Abstract: Insulin pumps control blood sugar in children with diabetes better than insulin injections, according to a new study.Published in the August 18, 2013, issue of the journal Diabetologia, the study was led by Stephanie R. Johnson with the Department of Endocrinology and Diabetes at the Princess ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • State Limits Specialty Copays to $150 Maximum per Fill
    • Abstract: Member cost sharing is one of the mainstays in pharmacy benefit management. In the state of Delaware, however, a new law puts a SI50 cap on specialty-drug copays, which will have insurers relying more heavily on other interventions to manage spending.The law signed by Governor Jack Markell will go ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Illinois Adopts Medical Marijuana Law
    • Abstract: from Staff ReportsIllinois has become the 21st state to legalize some form of medical marijuana with the establishment of a four-year pilot program that targets patients with chronic pain and debilitating conditions such as muscular dystrophy, cancer, and HIV.The Compassionate Use of Medical ... (Publication: Formulary)
      PubDate: Sun, 01 Sep 2013 00:00:00 -040
       
  • Breakthrough Therapy: FDA's New Designation for Accelerating Approval of
           Promising Pipeline Therapies
    • Abstract: FEDERAL AND STATE GOVERNMENT ACTIONS AND THEIR IMPACT ON DRUG DECISION-MAKERSIn July of 2012, a provision in the newly ratified FDA Safety and Innovation Act (FDASIA), paved the way for FDA to further assist drug manufacturers in expediting the development and introduction of new drugs ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Study Finds That Dapagliflozin Demonstrates Glycemic Responses Similar to
           Other Oral Agents
    • Abstract: from Staff ReportsDapagliflozin produces larger reductions in HbA]c in individuals who have higher baseline levels, according to a study presented in June at the American Diabetes Association 73rd Scientific Sessions, in Chicago.Dapagliflozin is a selective SGLT2 inhibitor that reduces ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Weekly Exenatide Treatment Yields Better Glycemic Control, Weight Loss
           Than Treatment with Insulin Glargine
    • Abstract: from Staff ReportsA recent international, open-label, randomized, controlled study of patients with type 2 diabetes mellitus compared once-weekly exenatide to titrated insulin glargine.The study, presented in June at the American Diabetes Association 73rd Scientific Sessions, in Chicago, included ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Patients with Type 2 Diabetes, History of CV Events Have High Rates of
           Additional CV Events
    • Abstract: 2013 AMERICAN DIABETES ASSOCIATION 73RD SCIENTIFIC SESSIONSfrom Staff ReportsIt is well known that type 2 diabetes mellitus is associated with increased risk of cardiovascular disease. A recent epidemiologic study conducted in the United Kingdom assessed the time to first major cardiovascular event ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Oral Oncolytics: Assessing Value of Newer Agents versus Current Standards
           of Care as Part of P&T Processes
    • Abstract: PEER-REVIEWED*AbstractOral oncolytics are relatively new to the field of cancer therapy. They currently make up about 25% of the oncology market and their use is continually expanding. The current insurance system is not efficiently equipped to handle the rapid expansion of oral oncolytics into the ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Rise in Mortality Risk Seen in Hysterectomized Women Aged 50 to 59 Not
           Using Estrogen Therapy
    • Abstract: A severe decline in the use of estrogen therapy (ET) due to misunderstanding the findings of the Women's Health Initiative (WHI) Estrogen Plus Progestin Trial has particularly affected hysterectomized women in their 50 s, leading to excess mortality, according to a study published online in the ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Lower Risk of Heart Failure and Stroke with Exenatide Than with Insulin
    • Abstract: 2013 AMERICAN DIABETES ASSOCIATION 73RD SCIENTIFIC SESSIONSIn this study, a group of 54,342 patients who were taking exenatide or insulin combined with oral anti-diabetes agents was followed for at least 3 years. Of this group, 39% of patients taking exenatide and 47% of patients taking insulin ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Examining Medication Reconciliation from a Perspective of Safety
    • Abstract: AbstractThe impact of medication reconciliation efforts on patient safety remains largely unknown. Recently published, systematically reviewed evidence suggests that there are certain characteristics of medication reconciliation processes that correlate favorably with clinically important patient ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Study Finds That Dapagliflozin Produces Similar Glycemic Efficacy to
           Glipizide
    • Abstract: from. Staff ReportsWhen metformin cannot maintain glycemic control, sulfonylureas are often used as add-on therapy in type 2 diabetes; however, risks include weight gain and hypoglycemia. Dapagliflozin is an SGLT2 inhibitor and increases urinary glucose excretion and reduces hyperglycemia ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Concomitant Control of BP, Cholesterol Is Difficult
    • Abstract: from Staff ReportsMany patients suffer from both hypertension and high cholesterol, putting them at greater risk of coronary heart disease (CHD). Controlling the hypertension and high cholesterol would reduce CHD risk by 50% or more, but less than a third of patients have achieved adequate control ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Triptans Widely Prescribed but Contraindicated in Patients with CV
           Conditions
    • Abstract: from Staff ReportsAlmost 5 million Americans with episodic migraine (EM) should not be prescribed a triptan-the only class of acute medications FDA approved and developed for migraine-because of the presence of cardiovascular contraindications, according to results from the American Migraine ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Once-Weekly Exenatide Is an Alternative Treatment to Daily Basal Insulin
    • Abstract: 2013 AMERICAN DIABETES ASSOCIATION 73RD SCIENTIFIC SESSIONSfrom Staff ReportsTypically, basal insulin is chosen as the add-on treatment in patients with severe hyperglycemia. However, it has been questioned whether it is the best option, according to research presented in June at American Diabetes ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Guideline Adds Aromatase Inhibitor for Breast Cancer Prevention
    • Abstract: from. Staff ReportsThe new update to the 2009 American Society of Clinical Oncology (ASCO) guideline on the pharmacologic interventions for breast cancer risk reduction now lists aromatase inhibitor exemestane (Aromasin, Pfizer) as an option for postmenopausal women for primary risk reduction who ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Ample Vaccine Supply Key to Combatting Unpredictability of Flu Season
    • Abstract: from Staff ReportsThe only predictable aspect of the influenza season is its unpredictability, according to experts.For example, the 2012-2013 influenza season was moderately severe, that started early and lasted longer than a usual influenza season. On the other hand, the 2011-2012 year was a mild ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Health Economic Analysis Shows Canagliflozin Monotherapy May Reduce Costs
           of Type 2 Diabetes
    • Abstract: Results from a health economic and outcomes research (HECOR) simulation analysis show that canagliflozin (Invokana, Janssen), along with lifestyle management, may reduce long-term complications and associated costs for adult patients with type 2 diabetes compared to a treatment sequence without ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Responsible Use of Drugs Could Save $200B Annually
    • Abstract: Delays in treatment and medication nonadherence are the major reasons behind avoidable costs in the healthcare system, according to an IMS study recently released.Avoidable costs of more than $200 billion are incurred each year in the US healthcare system, representing 8% of the country's total ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Without Optimal Treatment, Episodic Migraine May Progress to Chronic
           Migraine
    • Abstract: from Staff ReportsIndividuals with episodic migraine (EM; ICHD-2 defined migraine with headache on average 15 days per month) at higher rates without optimal treatment, according to a recent ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Unauthorized Prescribers Bill Part D $5 Million
    • Abstract: Estimates of the cost of fraud in the Medicare system range broadly from $17 billion to $90 billion. However, there are no estimates of-or methods to detect-how much of the wasted money is attributable to old-fashioned human error rather than blatant crime.A recent study from the Office of the ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • International Study Finds That Dapagliflozin Has Metabolic Benefits
    • Abstract: 2013 AMERICAN DIABETES ASSOCIATION 73RD SCIENTIFIC SESSIONSfrom Staff ReportsAn international study has found that dapagliflozin has sustained metabolic benefits compared with glipizide. Benefits included stable weight loss and low rates of hypoglycemia. Additionally, therapy was well-tolerated by ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Adherence Varies across Market Segments
    • Abstract: from Staff ReportsThe US healthcare system could avoid hundreds of millions of dollars in medical costs if medication adherence rates improved, according to a CVS Caremark report.The 2013 State of the States: Adherence Report projects potential costsavings within each state by examining medication ... (Publication: Formulary)
      PubDate: Thu, 01 Aug 2013 00:00:00 -050
       
  • Men's Health Network Urges Men to Get HPV Vaccine
    • Abstract: The Men's Health Network (MHN) is hoping actor Michael Douglas' assertion that his throat cancer was caused by human papillomavirus (HPV) contracted during oral sex will provoke more males to get the HPV vaccine."It's important to vaccinate boys as well as girls for the HPV virus; it is inefficient ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Efficacy of New Drugs Compared to Older Ones Not Dramatic, Study Says
    • Abstract: The effectiveness of new drugs compared with that of older drugs has fallen since the 1970s, according to a new study in Health Affairs.In the study, researchers randomly selected and analyzed the results of 315 clinical trials that compared a drug to a placebo from 4 medical journals: New England ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Underdosing in Obesity-An Epidemic: Focus on Antibiotics
    • Abstract: AbstractObesity is associated with an increased risk of infection. Unfortunately clinical tilals examining the safety and efficacy of antibiotics in obese patients are deficient Thus, clinicians predominately rely on pharmacokinetic and pharmacodynamic data for appropriate antibiotic dosing. The ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Utilization Management Programs May Increase Appropriate Use of Medication
           and Quality of Healthcare
    • Abstract: Prime Therapeutics LLC (Prime) is headquartered in St. Paul, Minn., and manages pharmacy benefits for health plans, employers, and government programs including Medicare and Medicaid. The company processes claims and delivers medicine to more than 21 million members, offering clinical services for ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Current Trends in Specialty Drug Utilization and Management: Payer
           Interventions in the Shadow of a Burgeoning Pipeline
    • Abstract: AbstractThe overall cost of medical benefits, provider-adminstered specialty drugs is roughly a quarter of a billion dollars per 1 million commercial lives, and the trend for the top 25 most costly drugs was 16%, a significant increase over last year's virtually flat trend. Payers are increasing ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Everolimus Combination Prolongs PFS in HER2-Positive Advanced Breast
           Cancer
    • Abstract: The addition of everolimus, an mTOR inhibitor, to trastuzumab and vinorelbine in heavily pretreated advanced breast cancer patients led to a 22% reduction in the risk of disease progression in the first phase 3 study showing that inhibition of human epidermal growth factor receptor-2 positive ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Nilotinib Leads to Sustained Responses in CML Patients with Residual
           Disease on Imatinib
    • Abstract: For chronic myeloid leukemia (CML) patients with minimal residual disease on long-term imatinib (Gleevec) therapy, switching to nilotinib (Tasigna) can lead to deep, sustained responses.The 2-year results from the ENESTcmr (Evaluating Nilotinib Efficacy and Safety in Clinical Trials - Complete ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Take 2 to 3 Minutes to Identify CVD Patients for More Counseling
    • Abstract: Face-to-face interaction between pharmacists and patients will be key to the success or failure of the federal government's Million Hearts initiative to prevent heart attacks and strokes, Salvatore Giorgianni, PharmD, told participants during the June 3 State of Men's HeartWebinar.Dr Giorgianni is ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Long-Term Data Reinforce Safety Profile of Dabigatran Etexilate Mesylate
    • Abstract: Results from the RELYABLE trial, the RE-LY extension study, support the long-term safety profile of dabigatran etexilate mesylate (Pradaxa, Boehringer Ingelheim Pharmaceuticals) 150 mg twice daily in patients with nonvalvular atrial fibrillation (NVAF), according to a study published in ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • AREDS Gets Another Look: Removing Beta-Carotene, Adding Lutein/zeaxanthin
           Shows Clear Benefits
    • Abstract: Investigators had already determined that the Age-Related Eye Disease Study (AREDS) formulation slowed the progression to advanced age-related macular degeneration (AMD), with a 25% decrease in the likelihood of progression to advanced AMD compared with placebo.Emily Y. Chew, MD, described those ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Octreotide LAR Extends Survival in Low Hepatic Load Neuroendocrine Tumors
    • Abstract: Octreotide LAR not only prolongs time to progression (TTP) but also appears to extend overall survival (OS) in a subgroup of patients with metastatic midgut neuroendocrine tumors (NETs) and a low hepatic load."A trend in longer survival in this subgroup is further indication to give octreotide LAR ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Training, Advising Pediatricians in Antibiotic Usage Improves Compliance
           with Prescription Guidelines
    • Abstract: Educating pediatricians in their offices, auditing their prescription patterns, and leveraging a shared electronic health record, encourages them to choose more appropriate antibiotics for children with commonrespiratory infections, according to a study published in the June 12 issue of the Journal ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • The Current State of HIV Therapy
    • Abstract: AbstractIncidence of human immunodeficiency viws (HIV) has decreased dramatically since its emergence in the early 1980s, but it remains a wotidwide epidemic. There is a reduction in newly diagnosed patients, but prevalence is increasing due to a longer life expectancy, which is attñbuted in part ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Four-Year Update Shows Nilotinib Induces Significantly Deeper Molecular
           Responses Than Imatinib
    • Abstract: The 4-year data from the landmark ENESTnd (Evaluating Nilotinib Efficacy and Safety in Clinical Trials - Newly Diagnosed Patients) trial continues to demonstrate the improved clinical benefit of front-line nilotinib (Tasigna) versus imatinib (Gleevec) in patients with newly diagnosed, Philadelphia ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Medicinal Cannabis Presents Unique Issues in Managed Care
    • Abstract: Medicinal cannabis, despite its emerging popularity, presents unique issues to managed care and hospital decision-makers. Exactly how does a quasi-legal substance, which has existed outside the sphere of mainstream medicine, become integrated into a traditional hospital and managed care ... (Publication: Formulary)
      PubDate: Mon, 01 Jul 2013 00:00:00 -050
       
  • Study Shows Patient Satisfaction with Pharmacy Program
    • Abstract: WHAT'S NEW IN DRUG RESEARCH AND MANAGED CARE PHARMACYImplementation of a pharmacy service that provides dosing, monitoring, education, and ensures safe transition from the inpatient to the outpatient setting is associated with improved patient satisfaction with overall care and with care related to ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -050
       
  • Increase in Genetic Tests Highlights Need for Oversight
    • Abstract: The availability of genetic and genomic tests is increasing at a rapid rate. The website genetests.org currently lists more than 2,700 inherited genetic disorders for which tests are available, and the number of available tests for inherited disorders increases at an annual rate of 25%, based on ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -050
       
  • Studies Show Increase Costs, Higher Use of Specialty Drugs to Treat
           Inflammatory Autoimmune Conditions
    • Abstract: FROM THE ACADEMY OF MANAGED CARE PHARMACY 2013 ANNUAL MEETINGBiologic anti-inflammatory (BAI) specialty medications to treat autoimmune inflammatory conditions-such as rheumatoid arthritis (RA), psoriasis or inflammatory bowel disease (eg, Crohn's disease, ulcerative colitis)- are among the most ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -050
       
  • Specialty Drugs Will Account for 50% of All Drug Costs by 2018
    • Abstract: FROM THE ACADEMY OF MANAGED CARE PHARMACY 2013 ANNUAL MEETINGHealth insurers should use both medical and pharmacy data to forecast specialty drug costs, which are predicted to rise to 50% of commercially insured total drug costs by 2018, according to a new study presented at the Academy of Managed ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -050
       
  • Increased Cardiac Risks in COPD with New Rx Inhalers
    • Abstract: Older patients with chronic obstructive pulmonary disease (COPD) may be at increased risk for cardiovascular events with newly prescribed long-acting beta-agonists (LABAs) and long-acting anticholinergics (LAAs) and need to be followed closely by their healthcare providers, according to a study ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -050
       
  • Efficiency, Less Utilization Fuels US Drug Spending Decline
    • Abstract: The growing use of generic medications and brand patent expirations are a major reasons that US spending on drugs declined in 2012, according to a new report.Total spending on medicines declined by 3.5%, according to the IMS Institute for Healthcare Informatics report, Declining Medicine Use and ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -050
       
  • Adhering to Generic Cholesterol-Lowering Drugs Is Associated with Lower
           Overall Costs of Care
    • Abstract: FROM THE ACADEMY OF MANAGED CARE PHARMACY 2013 ANNUAL MEETINGIndividuals who regularly take statins to reduce high cholesterol will see lower hospitalization rates according to a study presented at the Academy of Managed Care Pharmacy's 25th Annual Meeting & Expo in San Diego, in April.The study ... (Publication: Formulary)
      PubDate: Sat, 01 Jun 2013 00:00:00 -040
       
 
 
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