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Journal Cover   Acta Radiologica Open
  [3 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Online) 2058-4601
   Published by Sage Publications Homepage  [827 journals]
  • MRI with intrathecal MRI gadolinium contrast medium administration: a
           possible method to assess glymphatic function in human brain

    • Authors: Eide, P. K; Ringstad, G.
      Pages: 2058460115 - 2058460115
      Abstract: Recently, the "glymphatic system" of the brain has been discovered in rodents, which is a paravascular, transparenchymal route for clearance of excess brain metabolites and distribution of compounds in the cerebrospinal fluid. It has already been demonstrated that intrathecally administered gadolinium (Gd) contrast medium distributes along this route in rats, but so far not in humans. A 27-year-old woman underwent magnetic resonance imaging (MRI) with intrathecal administration of gadobutrol, which distributed throughout her entire brain after 1 and 4.5 h. MRI with intrathecal Gd may become a tool to study glymphatic function in the human brain.
      PubDate: 2015-11-17T05:47:40-08:00
      DOI: 10.1177/2058460115609635
      Issue No: Vol. 4, No. 11 (2015)
  • Scoring of the radiological picture of idiopathic interstitial pneumonia:
           a study to verify the reliability of the method

    • Authors: Kocova, E; Vanasek, J, Koblizek, V, Novosad, J, Elias, P, Bartos, V, Sterclova, M.
      Pages: 2058460115 - 2058460115
      Abstract: Background Idiopathic pulmonary fibrosis (IPF) is a clinical form of usual interstitial pneumonia (UIP). Computed chest tomography (CT) has a fundamental role in the multidisciplinary diagnostics. However, it has not been verified if and how a subjective opinion of a radiologists or pneumologists can influence the assessment and overall diagnostic summary. Purpose To verify the reliability of the scoring system. Material and Methods Assessment of conformity of the radiological score of high-resolution CT (HRCT) of lungs in patients with IPF was performed by a group of radiologists and pneumologists. Personal data were blinded and the assessment was performed independently using the Dutka/Vasakova scoring system (modification of the Gay system). The final score of the single assessors was then evaluated by means of the paired Spearman’s correlation and analysis of the principal components. Results Two principal components explaining cumulatively a 62% or 73% variability of the assessment of the single assessors were extracted during the analysis. The groups did not differ both in terms of specialty and experience with the assessment of the HRCT findings. Conclusion According to our study, scoring of a radiological image using the Dutka/Vasakova system is a reliable method in the hands of experienced radiologists. Significant differences occur during the assessment performed by pneumologists especially during the evaluation of the alveolar changes.
      PubDate: 2015-11-04T07:37:10-08:00
      DOI: 10.1177/2058460115605865
      Issue No: Vol. 4, No. 11 (2015)
  • Diagnosis of bone metastasis from thyroid carcinoma: a multidisciplinary

    • Authors: Bechsgaard, T; Lelkaitis, G, Jensen, K. E, Ewertsen, C.
      Pages: 2058460115 - 2058460115
      Abstract: Sarcomas are rare tumors originating from soft tissue or bone. Diagnosis and treatment of sarcomas should be performed at specialized sarcoma centers, where patients are evaluated at a multidisciplinary tumor conference. We present a case where sarcoma was suspected from magnetic resonance imaging (MRI), but histology revealed a metastasis from thyroid carcinoma, although the patient had no previous history of thyroid malignancy and resection of the thyroid gland was without malignancy. Ultrasound-guided biopsy was possible due to cortical destruction and the multidisciplinary approach with re-evaluation of previous pathology and a thorough patient history enabled a final diagnosis.
      PubDate: 2015-11-04T07:37:10-08:00
      DOI: 10.1177/2058460115603248
      Issue No: Vol. 4, No. 11 (2015)
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