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Journal Cover   Acta Radiologica Short Reports
  [3 followers]  Follow
  This is an Open Access Journal Open Access journal
   ISSN (Print) 2047-9816 - ISSN (Online) 2047-9816
   Published by Sage Publications Homepage  [813 journals]
  • MRI demyelination pattern and clinical course in a child with cerebral
           X-linked adrenoleukodystrophy (X-ALD)

    • Authors: Nowak, J; Lobel, U, Wolfl, M, Schlegel, P.-G, Warmuth-Metz, M.
      Pages: 2047981615 - 2047981615
      Abstract: The clinical spectrum in boys with X-linked adrenoleukodystrophy (X-ALD) ranges from isolated adrenocortical insufficiency and slowly progressive myelopathy to devastating cerebral demyelination. In the individual case, the disease course still remains unpredictable. Research findings suggest an important role of brain magnetic resonance imaging (MRI) lesion patterns as prognostic markers for X-ALD. Hence, familiarity with imaging features of childhood X-ALD in combination with clinical manifestation is required in order to stratify affected patients for therapy. We report on MRI findings and clinical course of cerebral X-ALD in a young boy with a rare subtype of white matter demyelination.
      PubDate: 2015-04-02T01:59:45-07:00
      DOI: 10.1177/2047981615573655
      Issue No: Vol. 4, No. 4 (2015)
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