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Blood
Journal Prestige (SJR): 6.434
Citation Impact (citeScore): 7
Number of Followers: 373  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0006-4971 - ISSN (Online) 1528-0020
Published by American Society of Hematology Homepage  [2 journals]
  • "> Introduction to a review series on secondary leukemia
    • Authors: Soulier; Jean
      Abstract: In this commissioned series of reviews introduced by Associate Editor Jean Soulier, experts provide new insights into the pathobiology of secondary acute myeloid leukemias arising in diverse genetic or acquired, benign or malignant hematologic disorders.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Oncogenesis by E2A-PBX1 in ALL: RUNX and more
    • Authors: Licht; Jonathan
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Occupy BTK: the key to controlling CLL
    • Authors: Thompson; Philip
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Mutant CALR functions: gains and losses
    • Authors: Prins; Daniel, Green, Anthony
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Create a healthy diet after transplant!
    • Authors: Teshima; Takanori
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> E2A-PBX1 functions as a coactivator for RUNX1 in acute lymphoblastic
           leukemia
    • Authors: Pi; Wen-Chieh, Wang, Jun, Shimada, Miho, Lin, Jia-Wei, Geng, Huimin, Lee, Yu-Ling, Lu, Rui, Li, Dongxu, Wang, Gang, Roeder, Robert, Chen, Wei-Yi
      Abstract: In a study reported in this Plenary Paper, Pi and colleagues used unbiased genomic profiling approaches and mechanistic studies to identify the direct and indirect target sites of the oncogenic fusion protein E2A-PBX1 in t(1,19)-positive pre-B acute lymphoblastic leukemia cells. They revealed how E2A-PBX1 acts in concert with RUNX1 to enforce transcriptome alterations underpinning the development of leukemia.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • child"> Oncogenesis by E2A-PBX1 in ALL: RUNX and more
    • Authors: Licht; Jonathan
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Secondary leukemia in patients with germline transcription factor
           mutations (RUNX1, GATA2, CEBPA)
    • Authors: Brown; Anna, Hahn, Christopher, Scott, Hamish
      Abstract: In this commissioned series of reviews introduced by Associate Editor Jean Soulier, experts provide new insights into the pathobiology of secondary acute myeloid leukemias arising in diverse genetic or acquired, benign or malignant hematologic disorders.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Secondary myelodysplastic syndrome and leukemia in acquired aplastic
           anemia and paroxysmal nocturnal hemoglobinuria
    • Authors: Sun; Lova, Babushok, Daria
      Abstract: In this commissioned series of reviews introduced by Associate Editor Jean Soulier, experts provide new insights into the pathobiology of secondary acute myeloid leukemias arising in diverse genetic or acquired, benign or malignant hematologic disorders.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Genetics of progression from MDS to secondary leukemia
    • Authors: Menssen; Andrew, Walter, Matthew
      Abstract: In this commissioned series of reviews introduced by Associate Editor Jean Soulier, experts provide new insights into the pathobiology of secondary acute myeloid leukemias arising in diverse genetic or acquired, benign or malignant hematologic disorders.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Leukemia secondary to myeloproliferative neoplasms
    • Authors: Dunbar; Andrew, Rampal, Raajit, Levine, Ross
      Abstract: In this commissioned series of reviews introduced by Associate Editor Jean Soulier, experts provide new insights into the pathobiology of secondary acute myeloid leukemias arising in diverse genetic or acquired, benign or malignant hematologic disorders.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Daratumumab plus CyBorD for patients with newly diagnosed AL
           amyloidosis: safety run-in results of ANDROMEDA
    • Authors: Palladini; Giovanni, Kastritis, Efstathios, Maurer, Mathew, Zonder, Jeffrey, Minnema, Monique, Wechalekar, Ashutosh, Jaccard, Arnaud, Lee, Hans, Bumma, Naresh, Kaufman, Jonathan, Medvedova, Eva, Kovacsovics, Tibor, Rosenzweig, Michael, Sanchorawala, Vaishali, Qin, Xiang, Vasey, Sandra, Weiss, Brendan, Vermeulen, Jessica, Merlini, Giampaolo, Comenzo, Raymond
      Abstract: Palladini et al provide early results of a prospective trial of subcutaneous daratumumab in combination with cyclophosphamide, bortezomib, and dexamethasone as first-line therapy for AL amyloidosis. They report that the regimen has high complete hematological and organ response rates and that toxicity is as expected with these classes of drugs.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Mitochondrial carrier homolog 2 is necessary for AML survival
    • Authors: Khan; Dilshad, Mullokandov, Michael, Wu, Yan, Voisin, Veronique, Gronda, Marcela, Hurren, Rose, Wang, Xiaoming, MacLean, Neil, Jeyaraju, Danny, Jitkova, Yulia, Xu, G., Laister, Rob, Seneviratne, Ayesh, Blatman, Zachary, Ketela, Troy, Bader, Gary, Marhon, Sajid, Carvalho, Daniel, Minden, Mark, Gross, Atan, Schimmer, Aaron
      Abstract: Arising in a screen to identify mitochondrial gene products necessary for the growth of acute myeloid leukemia (AML) cells, mitochondrial carrier homolog 2 (MTCH2) is shown to influence the differentiation of AML cells by toggling histone acetylation downstream of regulation of pyruvate metabolism.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Clinical and biological implications of target occupancy in CLL treated
           with the BTK inhibitor acalabrutinib
    • Authors: Sun; Clare, Nierman, Pia, Kendall, Ellen, Cheung, Jean, Gulrajani, Michael, Herman, Sarah, Pleyer, Christopher, Ahn, Inhye, Stetler-Stevenson, Maryalice, Yuan, Constance, Maric, Irina, Gaglione, Erika, Harris, Hailey, Pittaluga, Stefania, Wang, Min, Patel, Priti, Farooqui, Mohammed, Izumi, Raquel, Hamdy, Ahmed, Covey, Todd, Wiestner, Adrian
      Abstract: In a randomized phase 2 trial of acalabrutinib in patients with chronic lymphocytic leukemia (CLL), Sun et al documented that twice-daily dosing achieves higher Bruton tyrosine kinase (BTK) occupancy and pathway inhibition in lymph nodes than once-daily dosing and established the rate of BTK resynthesis in CLL cells. Both findings support the rationale for twice-daily dosing with this drug.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • child"> Occupy BTK: the key to controlling CLL
    • Authors: Thompson; Philip
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Calreticulin haploinsufficiency augments stem cell activity and is
           required for onset of myeloproliferative neoplasms in mice
    • Authors: Shide; Kotaro, Kameda, Takuro, Kamiunten, Ayako, Ozono, Yoshinori, Tahira, Yuki, Yokomizo-Nakano, Takako, Kubota, Sho, Ono, Masaya, Ikeda, Kazuhiko, Sekine, Masaaki, Akizuki, Keiichi, Nakamura, Kenichi, Hidaka, Tomonori, Kubuki, Yoko, Iwakiri, Hisayoshi, Hasuike, Satoru, Nagata, Kenji, Sashida, Goro, Shimoda, Kazuya
      Abstract: Shide and colleagues separated the functional roles of loss of a normal CALR allele and gain of a mutant CALR allele in murine models of CALR-driven essential thrombocythemia, providing insights into the development of some myeloproliferative neoplasms and stem cell biology.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • child"> Mutant CALR functions: gains and losses
    • Authors: Prins; Daniel, Green, Anthony
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> The role of AGK in thrombocytopoiesis and possible therapeutic
           strategies
    • Authors: Jiang; Haojie, Yu, Zhuo, Ding, Nan, Yang, Mina, Zhang, Lin, Fan, Xuemei, Zhou, Yuan, Zou, Qiang, Hou, Jian, Zheng, Junke, Zhang, Lei, Xu, Yanyan, Liu, Junling
      Abstract: Jiang et al used murine models to reveal critical nonenzymatic roles for acylglycerol kinase (AGK) in megakaryocyte differentiation and platelet biogenesis by enhancing JAK2/STAT3 signaling triggered by thrombopoietin.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> The microbe-derived short-chain fatty acids butyrate and propionate are
           associated with protection from chronic GVHD
    • Authors: Markey; Kate, Schluter, Jonas, Gomes, Antonio, Littmann, Eric, Pickard, Amanda, Taylor, Bradford, Giardina, Paul, Weber, Daniela, Dai, Anqi, Docampo, Melissa, Armijo, Gabriel, Slingerland, Ann, Slingerland, John, Nichols, Katherine, Brereton, Daniel, Clurman, Annelie, Ramos, Ruben, Rao, Arka, Bush, Amy, Bohannon, Lauren, Covington, Megan, Lew, Meagan, Rizzieri, David, Chao, Nelson, Maloy, Molly, Cho, Christina, Politikos, Ioannis, Giralt, Sergio, Taur, Ying, Pamer, Eric, Holler, Ernst, Perales, Miguel-Angel, Ponce, Doris, Devlin, Sean, Xavier, Joao, Sung, Anthony, Peled, Jonathan, Cross, Justin, Brink, Marcel
      Abstract: Markey and colleagues investigated the relationship between the gastrointestinal microbiome and chronic graft-versus-host disease (cGVHD), revealing that lower systemic concentrations of microbe-derived butyrate and propionate are associated with a higher chance of developing cGVHD in allogeneic hematopoietic stem cell transplant patients.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • child"> Create a healthy diet after transplant!
    • Authors: Teshima; Takanori
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Tocilizumab not associated with increased infection risk after CAR
           T-cell therapy: implications for COVID-19'
    • Authors: Frigault; Matthew, Nikiforow, Sarah, Mansour, Michael, Hu, Zhen-Huan, Horowitz, Mary, Riches, Marcie, Hematti, Peiman, Turtle, Cameron, Zhang, Mei-Jie, Perales, Miguel-Angel, Pasquini, Marcelo
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> RBCs prevent rapid PIEZO1 inactivation and expose slow deactivation as
           a mechanism of dehydrated hereditary stomatocytosis
    • Authors: Evans; Elizabeth, Povstyan, Oleksandr, Vecchis, Dario, Macrae, Fraser, Lichtenstein, Laeticia, Futers, T., Parsonage, Gregory, Humphreys, Neil, Adamson, Antony, Kalli, Antreas, Ludlow, Melanie, Beech, David
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> Impact of anticoagulation prior to COVID-19 infection: a propensity
           score–matched cohort study
    • Authors: Tremblay; Douglas, Gerwen, Maaike, Alsen, Mathilda, Thibaud, Santiago, Kessler, Alaina, Venugopal, Sangeetha, Makki, Iman, Qin, Qian, Dharmapuri, Sirish, Jun, Tomi, Bhalla, Sheena, Berwick, Shana, Feld, Jonathan, Mascarenhas, John, Troy, Kevin, Cromwell, Caroline, Dunn, Andrew, Oh, William, Naymagon, Leonard
      Abstract: Tremblay and colleagues asked whether patients receiving either routine anticoagulation or antiplatelet therapy for existing conditions prior to becoming ill with COVID-19 have different outcomes from patients receiving neither therapy. After matching for existing comorbidities, this retrospective observational study finds no evidence for an effect of prediagnosis anticoagulation on mortality.
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
  • "> A splenic lymphoma/leukemia with a spontaneous blast decrease without
           treatment
    • Authors: Friedrich; Chloé, Barreau, Sylvain
      PubDate: 2020-07-06T23:20:50-05:00
      Issue No: Vol. 136, No. 1 (2020)
       
 
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