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Journal Cover Science
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     ISSN (Print) 0036-8075 - ISSN (Online) 1095-9203
     Published by American Association for the Advancement of Science (AAAS) Homepage  [3 journals]   [SJR: 10.618]   [H-I: 739]
  • [Editorial] China's private universities
    • Authors: Huiqing Jin
      Abstract: China's expansion of universities has not been on a level playing field. Earlier this year, Education Minister Guiren Yuan declared that the government must treat both public and private universities equally. As founder and president of one of China's largest private universities, I wholeheartedly agree. China's private universities can help usher in new opportunities for social and economic development, but they must be enabled to launch robust education programs and compete for research grants. Unless the government loosens restrictions on such endeavors, private universities could enter a tailspin, and such an erosion of higher education could threaten social stability. Author: Huiqing Jin
      PubDate: 2014-10-24
      DOI: 10.1126/science.1262035
       
  • [In Brief] This week's section
    • Abstract: A roundup of weekly science policy and related news.
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.402
       
  • [In Depth] U.S. halts two dozen risky virus studies
    • Authors: Jocelyn Kaiser
      Abstract: One-year “pause” to develop new policy on controversial research that enhances pathogens. Author: Jocelyn Kaiser
      Keywords: Biosecurity
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.404
       
  • [In Depth] How we tamed ourselves—and became modern
    • Authors: Ann Gibbons
      Abstract: “Self-domestication” turned humans into the cooperative species we are today. Author: Ann Gibbons
      Keywords: Human Evolution
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.405
       
  • [In Depth] Epic pre-Columbian voyage suggested by genes
    • Authors: Andrew Lawler
      Abstract: South American DNA found in Easter Islanders. Author: Andrew Lawler
      Keywords: Migrations
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.406
       
  • [In Depth] Taiwan's ocean program reels from loss of ship, scientists
    • Authors: Dennis Normile
      Abstract: New vessel was sparking international collaborations. Author: Dennis Normile
      Keywords: Ocean Research
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.407
       
  • [In Depth] Election stakes go beyond control of the Senate
    • Authors: Jeffrey Mervis
      Abstract: Funding, peer review, water rules, fusion, and other science issues on tap after the vote. Author: Jeffrey Mervis
      Keywords: U.S. Policy
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.408-a
       
  • [In Depth] Does science suffer an ‘innovation deficit’?
    • Authors: Jeffrey Mervis
      Abstract: New catch phrase represents a two-edged sword for research community. Author: Jeffrey Mervis
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.408-b
       
  • [In Depth] Searching for science in India's traditional medicine
    • Authors: Priyanka Pulla
      Abstract: Critics say ayurgenomics is at best a quixotic quest. Author: Priyanka Pulla
      Keywords: Biomedical Research
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.410
       
  • [Feature] Show me the money
    • Authors: Mara Hvistendahl
      Abstract: A bitter dispute lays bare questionable practices in China's foreign-talent programs. Author: Mara Hvistendahl
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.411
       
  • [Perspective] Beyond the rainbow
    • Authors: Marie-Claire Koschowitz
      Abstract: Dinosaur color vision may have been key to the evolution of bird feathers
      Authors : Marie-Claire Koschowitz, Christian Fischer, Martin Sander
      Keywords: Evolution
      PubDate: 2014-10-24
      DOI: 10.1126/science.1258957
       
  • [Perspective] Terminating the replisome
    • Authors: Stephen P. Bell
      Abstract: Multiple proteins modify and dismantle a key enzyme after DNA replication terminates [Also see Research Article by Maric et al. and Report by Priego Moreno et al.] Author: Stephen P. Bell
      Keywords: DNA Replication
      PubDate: 2014-10-24
      DOI: 10.1126/science.1261245
       
  • [Perspective] Boundless no more
    • Authors: Amanda C. J. Vincent
      Abstract: Ending illegal, unregulated, and unreported fishing would bring hope for ocean wildlife
      Authors : Amanda C. J. Vincent, Jean M. Harris
      Keywords: Marine Science
      PubDate: 2014-10-24
      DOI: 10.1126/science.1255923
       
  • [Perspective] Harnessing chirality for valleytronics
    • Authors: Mark B. Lundeberg
      Abstract: Artificial magnetic fields bend electron trajectories in gapped graphene [Also see Report by Gorbachev et al.]
      Authors : Mark B. Lundeberg, Joshua A. Folk
      Keywords: Physics
      PubDate: 2014-10-24
      DOI: 10.1126/science.1260989
       
  • [Perspective] Sex and the single fern
    • Authors: Tai-ping Sun
      Abstract: Separation of the synthesis and sensing of a signaling molecule controls sex in ferns [Also see Report by Tanaka et al.] Author: Tai-ping Sun
      Keywords: Plant Science
      PubDate: 2014-10-24
      DOI: 10.1126/science.1260948
       
  • [Perspective] Breathing the unbreathable
    • Authors: Elizabeth Anne Edwards
      Abstract: A crystal structure reveals how some bacteria break down organohalide pollutants [Also see Report by Bommer et al.] Author: Elizabeth Anne Edwards
      Keywords: Microbiology
      PubDate: 2014-10-24
      DOI: 10.1126/science.1261194
       
  • [Perspective] Ratcheting the evolution of multicellularity
    • Authors: Eric Libby
      Abstract: Traits that entrench cells in a group lifestyle may pave the way for complexity
      Authors : Eric Libby, William C. Ratcliff
      Keywords: Evolution
      PubDate: 2014-10-24
      DOI: 10.1126/science.1262053
       
  • [Perspective] Unanchored ubiquitin in virus uncoating
    • Authors: Ricardo Rajsbaum
      Abstract: Components of a cellular degradation system are exploited by influenza virus during infection [Also see Report by Banerjee et al.]
      Authors : Ricardo Rajsbaum, Adolfo García-Sastre
      Keywords: Virology
      PubDate: 2014-10-24
      DOI: 10.1126/science.1261509
       
  • [Policy Forum] Coping with the curse of freshwater variability
    • Authors: J. W. Hall
      Abstract: Institutions, infrastructure, and information for adaptation
      Authors : J. W. Hall, D. Grey, D. Garrick, F. Fung, C. Brown, S. J. Dadson, C. W. Sadoff
      Keywords: Water Security
      PubDate: 2014-10-24
      DOI: 10.1126/science.1257890
       
  • [Book Review] The rise and fall of the nation's doctor
    • Authors: Jonathan M. Samet
      Abstract: Author: Jonathan M. Samet
      Keywords: History of Medicine
      PubDate: 2014-10-24
      DOI: 10.1126/science.1260189
       
  • [Book Review] Science on the silver screen
    • Authors: Caroline Ash
      Abstract: Author: Caroline Ash
      Keywords: Film
      PubDate: 2014-10-24
      DOI: 10.1126/science.1261999
       
  • [Books et al.] Books Received
    • Abstract: A listing of books received at Science during the week ending 17 October 2014.
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.432-b
       
  • [Letter] Ebola: Mobility data
    • Authors: M. Elizabeth Halloran
      Abstract:
      Authors : M. Elizabeth Halloran, Alessandro Vespignani, Nita Bharti, Leora R. Feldstein, K. A. Alexander, Matthew Ferrari, Jeffrey Shaman, John M. Drake, Travis Porco, Joseph N. S. Eisenberg, Sara Y. Del Valle, Eric Lofgren, Samuel V. Scarpino, Marisa C. Eisenberg, Daozhou Gao, James M. Hyman, Stephen Eubank, Ira M. Longini
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.433-a
       
  • [Letter] Ebola: Public-private partnerships
    • Authors: L. A. Reperant
      Abstract:
      Authors : L. A. Reperant, L. H. M. van de Burgwal, E. Claassen, A. D. M. E. Osterhaus
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.433-b
       
  • [Letter] Ebola: Social research overlooked
    • Authors: Gilles Guerrier
      Abstract: Author: Gilles Guerrier
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.434-a
       
  • [Technical Comment] Comment on “A Jurassic ornithischian dinosaur
           from Siberia with both feathers and scales”
    • Authors: Theagarten Lingham-Soliar
      Abstract: Godefroit et al. (Reports, 25 July 2014, p. 451) reported scales and feathers, including “basal plates,” in an ornithischian dinosaur. Their arguments against the filaments being collagen fibers are not supported because of a fundamental misinterpretation of such structures and underestimation of their size. The parsimonious explanation is that the filaments are support fibers in association with badly degraded scales and that they do not represent early feather stages. Author: Theagarten Lingham-Soliar
      PubDate: 2014-10-24
      DOI: 10.1126/science.1259983
       
  • [Technical Response] Response to Comment on “A Jurassic
           ornithischian dinosaur from Siberia with both feathers and scales”
    • Authors: Pascal Godefroit
      Abstract: Lingham-Soliar questions our interpretation of integumentary structures in the Middle-Late Jurassic ornithischian dinosaur Kulindadromeus as feather-like appendages and alternatively proposes that the compound structures observed around the humerus and femur of Kulindadromeus are support fibers associated with badly degraded scales. We consider this hypothesis highly unlikely because of the taphonomy and morphology of the preserved structures.
      Authors : Pascal Godefroit, Sofia M. Sinitsa, Danielle Dhouailly, Yuri L. Bolotsky, Alexander V. Sizov, Maria E. McNamara, Michael J. Benton, Paul Spagna
      PubDate: 2014-10-24
      DOI: 10.1126/science.1260146
       
  • This Week in Science
    • Authors: Sacha Vignieri
      Abstract: Making adjustments for a new neighborhood Digital amplification of T cell receptor signals Mountain dwellers of the Pleistocene Flu mimics damaged proteins during entry Making use of graphene's valleys Layering on solar cell power and stability Building with alphahelical coiled coils Anticancer drug coming out on TOPK How bacteria break down organohalides Experimental platforms for probing bacteria From single molecules to embryos in living color How to stop after copying the genome How to make vanadium dioxide metallic Ensuring handedness when breaking C-H bonds Identifying the workhorse of working memory Sex determination driven by community cooperation Addressing fishing threats to ocean wildlife Dinosaur color vision and the evolution of feathers
      Keywords: Evolutionary Biology
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.435-a
       
  • Editors' Choice
    • Authors: Stella M. Hurtley
      Abstract: Actin reins in plant cell division When winter snowfall trumps summer melting A primate model of Alzheimer's disease Helping palladium atoms stand apart For radiotherapy, less can be more Blending polymers with Janus particles A microRNA for retinal regeneration
      Keywords: Plant Cell Division
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.436-a
       
  • [Review] Zooming in to see the bigger picture: Microfluidic and
           nanofabrication tools to study bacteria
    • Authors: Felix J. H. Hol
      Abstract: The spatial structure of natural habitats strongly affects bacterial life, ranging from nanoscale structural features that individual cells exploit for surface attachment, to micro- and millimeter-scale chemical gradients that drive population-level processes. Nanofabrication and microfluidics are ideally suited to manipulate the environment at those scales and have emerged as powerful tools with which to study bacteria. Here, we review the new scientific insights gained by using a diverse set of nanofabrication and microfluidic techniques to study individual bacteria and multispecies communities. This toolbox is beginning to elucidate disparate bacterial phenomena—including aging, electron transport, and quorum sensing—and enables the dissection of environmental communities through single-cell genomics. A more intimate integration of microfluidics, nanofabrication, and microbiology will enable further exploration of bacterial life at the smallest scales.
      Authors : Felix J. H. Hol, Cees Dekker
      PubDate: 2014-10-24
      DOI: 10.1126/science.1251821
       
  • [Research Article] Lattice light-sheet microscopy: Imaging molecules to
           embryos at high spatiotemporal resolution
    • Authors: Bi-Chang Chen
      Abstract: A new microscope allows three-dimensional imaging of living systems at very high resolution in real time.
      Authors : Bi-Chang Chen, Wesley R. Legant, Kai Wang, Lin Shao, Daniel E. Milkie, Michael W. Davidson, Chris Janetopoulos, Xufeng S. Wu, John A. Hammer, Zhe Liu, Brian P. English, Yuko Mimori-Kiyosue, Daniel P. Romero, Alex T. Ritter, Jennifer Lippincott-Schwartz, Lillian Fritz-Laylin, R. Dyche Mullins, Diana M. Mitchell, Joshua N. Bembenek, Anne-Cecile Reymann, Ralph Böhme, Stephan W. Grill, Jennifer T. Wang, Geraldine Seydoux, U. Serdar Tulu, Daniel P. Kiehart, Eric Betzig
      PubDate: 2014-10-24
      DOI: 10.1126/science.1257998
       
  • [Research Article] Cdc48 and a ubiquitin ligase drive disassembly of the
           CMG helicase at the end of DNA replication
    • Authors: Marija Maric
      Abstract: DNA replication machinery stably encircles replicating DNA and is actively disassembled once replication is complete. [Also see Perspective by Bell]
      Authors : Marija Maric, Timurs Maculins, Giacomo De Piccoli, Karim Labib
      PubDate: 2014-10-24
      DOI: 10.1126/science.1253596
       
  • [Report] Fulleropyrrolidine interlayers: Tailoring electrodes to raise
           organic solar cell efficiency
    • Authors: Zachariah A. Page
      Abstract: A polar fullerene derivative layered on the cathode of a polymer solar cell fosters simultaneous stability and efficiency.
      Authors : Zachariah A. Page, Yao Liu, Volodimyr V. Duzhko, Thomas P. Russell, Todd Emrick
      PubDate: 2014-10-24
      DOI: 10.1126/science.1255826
       
  • [Report] A photoinduced metal-like phase of monoclinic VO2 revealed by
           ultrafast electron diffraction
    • Authors: Vance R. Morrison
      Abstract: Simultaneous measurements of structural and optical properties are used to study optically excited vanadium dioxide.
      Authors : Vance R. Morrison, Robert. P. Chatelain, Kunal L. Tiwari, Ali Hendaoui, Andrew Bruhács, Mohamed Chaker, Bradley J. Siwick
      PubDate: 2014-10-24
      DOI: 10.1126/science.1253779
       
  • [Report] Detecting topological currents in graphene superlattices
    • Authors: R. V. Gorbachev
      Abstract: Graphene is aligned with a layer of hexagonal boron nitride to achieve the valley Hall effect. [Also see Perspective by Lundeberg and Folk]
      Authors : R. V. Gorbachev, J. C. W. Song, G. L. Yu, A. V. Kretinin, F. Withers, Y. Cao, A. Mishchenko, I. V. Grigorieva, K. S. Novoselov, L. S. Levitov, A. K. Geim
      PubDate: 2014-10-24
      DOI: 10.1126/science.1254966
       
  • [Report] Room-temperature enantioselective C–H iodination via
           kinetic resolution
    • Authors: Ling Chu
      Abstract: Palladium catalysis produces benzylamine derivatives of interest in medicinal chemistry.
      Authors : Ling Chu, Kai-Jiong Xiao, Jin-Quan Yu
      PubDate: 2014-10-24
      DOI: 10.1126/science.1258538
       
  • [Report] Structural basis for organohalide respiration
    • Authors: Martin Bommer
      Abstract: The crystal structure of a reductive dehalogenase shows how bacteria break down organohalide contaminants. [Also see Perspective by Edwards]
      Authors : Martin Bommer, Cindy Kunze, Jochen Fesseler, Torsten Schubert, Gabriele Diekert, Holger Dobbek
      PubDate: 2014-10-24
      DOI: 10.1126/science.1258118
       
  • [Report] Medial prefrontal activity during delay period contributes to
           learning of a working memory task
    • Authors: Ding Liu
      Abstract: Optogenetic manipulation of neuronal activity as memories form can impair acquisition of working memory.
      Authors : Ding Liu, Xiaowei Gu, Jia Zhu, Xiaoxing Zhang, Zhe Han, Wenjun Yan, Qi Cheng, Jiang Hao, Hongmei Fan, Ruiqing Hou, Zhaoqin Chen, Yulei Chen, Chengyu T. Li
      PubDate: 2014-10-24
      DOI: 10.1126/science.1256573
       
  • [Report] Rapid evolution of a native species following invasion by a
           congener
    • Authors: Y. E. Stuart
      Abstract: On small islands in Florida, native lizards adapt to higher perches following invasion by a related species.
      Authors : Y. E. Stuart, T. S. Campbell, P. A. Hohenlohe, R. G. Reynolds, L. J. Revell, J. B. Losos
      PubDate: 2014-10-24
      DOI: 10.1126/science.1257008
       
  • [Report] Paleoindian settlement of the high-altitude Peruvian Andes
    • Authors: Kurt Rademaker
      Abstract: Artifacts and rock shelters indicate hunter-gatherer presence at ~4500 meters above sea level, 12.8 to 11.5 thousand years ago.
      Authors : Kurt Rademaker, Gregory Hodgins, Katherine Moore, Sonia Zarrillo, Christopher Miller, Gordon R. M. Bromley, Peter Leach, David A. Reid, Willy Yépez Álvarez, Daniel H. Sandweiss
      PubDate: 2014-10-24
      DOI: 10.1126/science.1258260
       
  • [Report] Antheridiogen determines sex in ferns via a spatiotemporally
           split gibberellin synthesis pathway
    • Authors: Junmu Tanaka
      Abstract: A biosynthetic pathway split between young and old individual ferns controls hormonal signaling that regulates sex determination. [Also see Perspective by Sun]
      Authors : Junmu Tanaka, Kenji Yano, Koichiro Aya, Ko Hirano, Sayaka Takehara, Eriko Koketsu, Reynante Lacsamana Ordonio, Seung-Hyun Park, Masatoshi Nakajima, Miyako Ueguchi-Tanaka, Makoto Matsuoka
      PubDate: 2014-10-24
      DOI: 10.1126/science.1259923
       
  • [Report] Influenza A virus uses the aggresome processing machinery for
           host cell entry
    • Authors: Indranil Banerjee
      Abstract: A flu virus mimics misfolded protein aggregates and hijacks associated cellular machinery early during infection. [Also see Perspective by Rajsbaum and García-Sastre]
      Authors : Indranil Banerjee, Yasuyuki Miyake, Samuel Philip Nobs, Christoph Schneider, Peter Horvath, Manfred Kopf, Patrick Matthias, Ari Helenius, Yohei Yamauchi
      PubDate: 2014-10-24
      DOI: 10.1126/science.1257037
       
  • [Report] Polyubiquitylation drives replisome disassembly at the
           termination of DNA replication
    • Authors: Sara Priego Moreno
      Abstract: DNA replication machinery stably encircles replicating DNA and is actively disassembled once replication is complete. [Also see Perspective by Bell]
      Authors : Sara Priego Moreno, Rachael Bailey, Nicholas Campion, Suzanne Herron, Agnieszka Gambus
      PubDate: 2014-10-24
      DOI: 10.1126/science.1253585
       
  • [Report] High thermodynamic stability of parametrically designed helical
           bundles
    • Authors: Po-Ssu Huang
      Abstract: Protein design expands the repertoire of coiled-coil structures to α-helical barrels and hyperstable helical bundles.
      Authors : Po-Ssu Huang, Gustav Oberdorfer, Chunfu Xu, Xue Y. Pei, Brent L. Nannenga, Joseph M. Rogers, Frank DiMaio, Tamir Gonen, Ben Luisi, David Baker
      PubDate: 2014-10-24
      DOI: 10.1126/science.1257481
       
  • [Report] Computational design of water-soluble α-helical barrels
    • Authors: Andrew R. Thomson
      Abstract: Protein design expands the repertoire of coiled-coil structures to α-helical barrels and hyperstable helical bundles.
      Authors : Andrew R. Thomson, Christopher W. Wood, Antony J. Burton, Gail J. Bartlett, Richard B. Sessions, R. Leo Brady, Derek N. Woolfson
      PubDate: 2014-10-24
      DOI: 10.1126/science.1257452
       
  • [New Products] New Products
    • Abstract: A weekly roundup of information on newly offered instrumentation, apparatus, and laboratory materials of potential interest to researchers.
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.489-a
       
  • [Podcast] Science Podcast: 24 October Show
    • Abstract: On this week's show: The earliest high-altitude humans.
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.489-b
       
  • [Business Office Feature] Innovations in light sheet microscopy:
           Strategies and new applications
    • Authors: Thai Truong
      Abstract: Thai Truong
      Keywords: Science Webinar Series
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.489-c
       
  • [Association Affairs] AAAS 2015 Annual Meeting Program
    • Abstract: This issue of Science includes the program of the 2015 AAAS Annual Meeting. The theme of the AAAS Annual Meeting in San Jose, CA, 12 to 16 February 2015, is Innovations, Information, and Imaging.A PDF of the program as it appears in this issue is available here; for more information on the meeting (including registration forms and information on accommodations), please visit www.aaas.org/meetings/.
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.490
       
  • [Working Life] A double dose of advice
    • Authors: Huan Wang
      Abstract: Author: Huan Wang
      PubDate: 2014-10-24
      DOI: 10.1126/science.346.6208.510
       
 
 
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