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Journal Cover Nature Reviews Neuroscience
  [SJR: 21.499]   [H-I: 309]   [299 followers]  Follow
    
   Full-text available via subscription Subscription journal  (Not entitled to full-text)
   ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
   Published by NPG Homepage  [127 journals]
  • Learning and memory: Space and time connections
    • Authors: Natasha Bray
      Pages: 127 - 127
      Abstract: Direct projections from the dorsal and intermediate CA1 to the medial prefrontal cortex in rats are crucial for the retrieval of temporal and spatial aspects of episodic memory, respectively.
      Citation: Nature Reviews Neuroscience 18, 127 (2017)
      PubDate: 2017-01-27
      DOI: 10.1038/nrn.2017.11
      Issue No: Vol. 18, No. 3 (2017)
       
  • Learning and memory: I remember it well...
    • Authors: Sian Lewis
      Pages: 128 - 128
      Abstract: Extended periods of exposure to emotional stimuli result in increased functional connectivity between the amygdala and the anterior hippocampus, which strengthens memory consolidation and subsequent recall of neutral stimuli experienced during this altered brain state.
      Citation: Nature Reviews Neuroscience 18, 128 (2017)
      PubDate: 2017-01-27
      DOI: 10.1038/nrn.2017.12
      Issue No: Vol. 18, No. 3 (2017)
       
  • Sensory systems: Sensational organization in the dorsal horn
    • Authors: Katherine Whalley
      Pages: 128 - 128
      Abstract: This study dissects the complex interneuron networks that contribute to the processing of innocuous touch-information in the spinal cord.
      Citation: Nature Reviews Neuroscience 18, 128 (2017)
      PubDate: 2017-01-27
      DOI: 10.1038/nrn.2017.9
      Issue No: Vol. 18, No. 3 (2017)
       
  • Prefrontal cortex: Down in front
    • Authors: Natasha Bray
      Pages: 129 - 129
      Abstract: Disruption of nicotinic acetylcholine receptor (nAChR) signalling in the prefrontal cortex has been suggested to underlie cognitive deficits in schizophrenia. In this study, mice expressing a variant of human nAChR subunit α5 implicated in schizophrenia showed impaired sociability and sensorimotor gating. Two-photon calcium imaging revealed
      Citation: Nature Reviews Neuroscience 18, 129 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.16
      Issue No: Vol. 18, No. 3 (2017)
       
  • Neurodegenerative disease: Losing the way
    • Authors: Natasha Bray
      Pages: 129 - 129
      Abstract: Individuals with Alzheimer disease (AD) often have difficulties with spatial navigation, which depends on the entorhinal cortex (EC), but whether tau aggregates affect the EC in AD is unclear. Fu et al. studied mice expressing aggregable human tau in the hippocampal formation (EC-tau mice). Compared
      Citation: Nature Reviews Neuroscience 18, 129 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.17
      Issue No: Vol. 18, No. 3 (2017)
       
  • Behavioural neuroscience: Right on (social) cue
    • Authors: Natasha Bray
      Pages: 129 - 129
      Abstract: The neural circuitry mediating the ability to produce learned responses to social cues is unknown. Here, 'observer' rats watched 'demonstrator' rats that received footshocks paired with a tone; with social learning, observers learned to freeze in response to the tone. Chemogenetic inhibition of lateral amygdala
      Citation: Nature Reviews Neuroscience 18, 129 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.18
      Issue No: Vol. 18, No. 3 (2017)
       
  • Cell biology of the neuron: Adding fuel to the firing
    • Authors: Natasha Bray
      Pages: 129 - 129
      Abstract: Neuronal activity promotes glycolysis at terminals to sustain synaptic vesicle (SV) recycling; however, the underlying mechanisms are not known. Ashrafi et al. expressed a pHluorin-tagged variant of the glucose transporter GLUT4 in rat hippocampal neurons and showed that, with sustained firing of action potentials,
      Citation: Nature Reviews Neuroscience 18, 129 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.19
      Issue No: Vol. 18, No. 3 (2017)
       
  • Synaptic transmission: Recycling regulators
    • Authors: Katherine Whalley
      Pages: 130 - 130
      Abstract: The mechanisms that regulate synaptic vesicle recycling are unclear. Here, Li et al. show that Ca2+ sensors that drive vesicle fusion also influence vesicle endocytosis. High-resolution recordings of fluorescently tagged vesicles revealed a role of synaptotagmin 1 in the regulation of the
      Citation: Nature Reviews Neuroscience 18, 130 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.20
      Issue No: Vol. 18, No. 3 (2017)
       
  • Sleep and memory: REM sleep targets new synapses
    • Authors: Katherine Whalley
      Pages: 130 - 130
      Abstract: To support neural circuit stability and memory function, new synapses must be selectively pruned or maintained. Li et al. used two-photon imaging of the dendritic spines of mouse primary motor cortex pyramidal neurons to demonstrate the role of rapid eye movement (REM) sleep in
      Citation: Nature Reviews Neuroscience 18, 130 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.21
      Issue No: Vol. 18, No. 3 (2017)
       
  • Pain: Improving opioids
    • Authors: Katherine Whalley
      Pages: 130 - 130
      Abstract: Chronic use of opioid analgesics can cause analgesic tolerance and opioid-induced hyperalgesia (OIH), contributing to dose escalation in patients. Corder et al. here provide evidence that, in mice, these unwanted effects, and the underlying altered circuit plasticity, are mediated by μ opioid receptors (MORs)
      Citation: Nature Reviews Neuroscience 18, 130 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.22
      Issue No: Vol. 18, No. 3 (2017)
       
  • Neuromodulation: A circuit modulator
    • Authors: Katherine Whalley
      Pages: 130 - 130
      Abstract: The cytokine IL-17 is expressed in the brain, but its function is not known. Chen et al. found that the Caenorhabditis elegans orthologue of IL-17 regulates the aggregation of worms following a rise in environmental oxygen and that it mediates this effect by
      Citation: Nature Reviews Neuroscience 18, 130 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2017.23
      Issue No: Vol. 18, No. 3 (2017)
       
  • Glia: A toxic reaction
    • Authors: Darran Yates
      Pages: 130 - 130
      Abstract: Activated microglia induce a subtype of reactive astrocytes that is toxic to various neuronal types and oligodendrocytes and that is found in various neurological disorders.
      Citation: Nature Reviews Neuroscience 18, 130 (2017)
      PubDate: 2017-02-02
      DOI: 10.1038/nrn.2017.13
      Issue No: Vol. 18, No. 3 (2017)
       
  • Micro-connectomics: probing the organization of neuronal networks at the
           cellular scale
    • Authors: Manuel Schröter, Ole Paulsen, Edward T. Bullmore
      Pages: 131 - 146
      Abstract: Defining the organizational principles of neuronal networks at the cellular scale, or micro-connectomics, is a key challenge of modern neuroscience. In this Review, we focus on graph theoretical parameters of micro-connectome topology, often informed by economical principles that conceptually originated with Ramón y Cajal's conservation
      Citation: Nature Reviews Neuroscience 18, 131 (2017)
      PubDate: 2017-02-02
      DOI: 10.1038/nrn.2016.182
      Issue No: Vol. 18, No. 3 (2017)
       
  • SHANK proteins: roles at the synapse and in autism spectrum disorder
    • Authors: Patricia Monteiro, Guoping Feng
      Pages: 147 - 157
      Abstract: Several large-scale genomic studies have supported an association between cases of autism spectrum disorder and mutations in the genes SH3 and multiple ankyrin repeat domains protein 1 (SHANK1), SHANK2 and SHANK3, which encode a family of postsynaptic scaffolding proteins that are
      Citation: Nature Reviews Neuroscience 18, 147 (2017)
      PubDate: 2017-02-09
      DOI: 10.1038/nrn.2016.183
      Issue No: Vol. 18, No. 3 (2017)
       
  • Fractionating impulsivity: neuropsychiatric implications
    • Authors: Jeffrey W. Dalley, Trevor W. Robbins
      Pages: 158 - 171
      Abstract: The ability to make decisions and act quickly without hesitation can be advantageous in many settings. However, when persistently expressed, impulsive decisions and actions are considered risky, maladaptive and symptomatic of such diverse brain disorders as attention-deficit hyperactivity disorder, drug addiction and affective disorders. Over
      Citation: Nature Reviews Neuroscience 18, 158 (2017)
      PubDate: 2017-02-17
      DOI: 10.1038/nrn.2017.8
      Issue No: Vol. 18, No. 3 (2017)
       
  • A distributed, hierarchical and recurrent framework for reward-based
           choice
    • Authors: Laurence T. Hunt, Benjamin Y. Hayden
      Pages: 172 - 182
      Abstract: Many accounts of reward-based choice argue for distinct component processes that are serial and functionally localized. In this Opinion article, we argue for an alternative viewpoint, in which choices emerge from repeated computations that are distributed across many brain regions. We emphasize how several features
      Citation: Nature Reviews Neuroscience 18, 172 (2017)
      PubDate: 2017-02-17
      DOI: 10.1038/nrn.2017.7
      Issue No: Vol. 18, No. 3 (2017)
       
  • The contribution of the human posterior parietal cortex to episodic memory
    • Authors: Carlo Sestieri, Gordon L. Shulman, Maurizio Corbetta
      Pages: 183 - 192
      Abstract: The posterior parietal cortex (PPC) is traditionally associated with attention, perceptual decision making and sensorimotor transformations, but more recent human neuroimaging studies support an additional role in episodic memory retrieval. In this Opinion article, we present a functional–anatomical model of the involvement of the PPC
      Citation: Nature Reviews Neuroscience 18, 183 (2017)
      PubDate: 2017-02-17
      DOI: 10.1038/nrn.2017.6
      Issue No: Vol. 18, No. 3 (2017)
       
 
 
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