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Journal Cover Nature Reviews Neuroscience
  [SJR: 14.685]   [H-I: 259]   [246 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
   Published by NPG Homepage  [123 journals]
  • Behavioural neuroscience: On the defensive
    • Authors: Natasha Bray
      Pages: 463 - 463
      Abstract: A disinhibitory circuit involving the central nucleus of the amygdala, inhibitory and excitatory neurons in the ventrolateral periaqueductal grey and premotor neurons in the medulla controls freezing behaviour in response to threat.
      Citation: Nature Reviews Neuroscience 17, 463 (2016)
      PubDate: 2016-06-23
      DOI: 10.1038/nrn.2016.88
      Issue No: Vol. 17, No. 8 (2016)
       
  • Neurodevelopmental disorders: Touching on the issue
    • Authors: Darran Yates
      Pages: 464 - 465
      Abstract: Developmental dysfunction in peripheral somatosensory neurons causes altered responses to tactile stimuli and other behavioural deficits in mouse models of autism spectrum disorder.
      Citation: Nature Reviews Neuroscience 17, 464 (2016)
      PubDate: 2016-07-07
      DOI: 10.1038/nrn.2016.91
      Issue No: Vol. 17, No. 8 (2016)
       
  • Spatial processing: Route finder
    • Authors: Darran Yates
      Pages: 465 - 465
      Abstract: Hippocampal place cell firing is thought to encode the location of an animal in its environment. However, in rats continually passing the same location to reach different places, the firing of place cells linked to that location seems to be influenced by their start or
      Citation: Nature Reviews Neuroscience 17, 465 (2016)
      PubDate: 2016-07-19
      DOI: 10.1038/nrn.2016.98
      Issue No: Vol. 17, No. 8 (2016)
       
  • GLIA: Matching the demand
    • Authors: Darran Yates
      Pages: 465 - 465
      Abstract: Oligodendrocytes provide support to axons by supplying lactate for aerobic ATP production, but the regulation of this process is unclear. Axons can release glutamate during phases of neuronal activity, and NMDA-type glutamate receptors (NMDARs) are found in oligodendrocytes, although the function of these receptors is
      Citation: Nature Reviews Neuroscience 17, 465 (2016)
      PubDate: 2016-07-19
      DOI: 10.1038/nrn.2016.97
      Issue No: Vol. 17, No. 8 (2016)
       
  • Metabolism: Promoting obesity
    • Authors: Darran Yates
      Pages: 465 - 465
      Abstract: Obesity has been linked to changes in plasma and faecal levels of short-chain fatty acids, including acetate, but whether these changes cause weight gain is unclear. Perry et al. found that rats receiving a high-fat diet developed an increase in whole-body acetate levels that
      Citation: Nature Reviews Neuroscience 17, 465 (2016)
      PubDate: 2016-07-19
      DOI: 10.1038/nrn.2016.96
      Issue No: Vol. 17, No. 8 (2016)
       
  • Emotion: Fast fear
    • Authors: Darran Yates
      Pages: 465 - 465
      Abstract: Rodent studies suggest the existence of a subcortical pathway that rapidly processes threat-related information, but direct evidence for such a pathway in primates has been lacking. Here, people with epilepsy who had been implanted with intracranial electrodes in the amygdala and, in some cases, in
      Citation: Nature Reviews Neuroscience 17, 465 (2016)
      PubDate: 2016-07-19
      DOI: 10.1038/nrn.2016.95
      Issue No: Vol. 17, No. 8 (2016)
       
  • Synaptic plasticity: Keeping synapses quiet
    • Authors: Sian Lewis
      Pages: 465 - 465
      Abstract: Although both cocaine and morphine administration induce silent synapses in dopaminergic medium spiny neurons and produce similar behavioural changes, they do so through different mechanisms and by affecting different neuronal sub-populations.
      Citation: Nature Reviews Neuroscience 17, 465 (2016)
      PubDate: 2016-06-23
      DOI: 10.1038/nrn.2016.89
      Issue No: Vol. 17, No. 8 (2016)
       
  • Neurophysiology: Local tuning of spike shape
    • Authors: Katherine Whalley
      Pages: 466 - 466
      Abstract: In stellate cell axons, axon potential width is determined in a synapse-specific manner by the compartmentalized clustering of Kv3 channels.
      Citation: Nature Reviews Neuroscience 17, 466 (2016)
      PubDate: 2016-07-19
      DOI: 10.1038/nrn.2016.99
      Issue No: Vol. 17, No. 8 (2016)
       
  • Synaptic plasticity: Feast or famine
    • Authors: Sian Lewis
      Pages: 466 - 466
      Abstract: AMP-activated protein kinase (AMPK), which is expressed in the hypothalamus and activated by fasting, is shown to increase the phosphorylation of p21-activated kinase 2 (PAK2), and induce spinogenesis and an increase in excitatory neurotransmission in hypothalamic AgRP neurons.
      Citation: Nature Reviews Neuroscience 17, 466 (2016)
      PubDate: 2016-07-07
      DOI: 10.1038/nrn.2016.90
      Issue No: Vol. 17, No. 8 (2016)
       
  • Autophagy in acute brain injury
    • Pages: 467 - 484
      Abstract: Autophagy is an evolutionarily ancient mechanism that ensures the lysosomal degradation of old, supernumerary or ectopic cytoplasmic entities. Most eukaryotic cells, including neurons, rely on proficient autophagic responses for the maintenance of homeostasis in response to stress. Accordingly, autophagy mediates neuroprotective effects following some forms
      Citation: Nature Reviews Neuroscience 17, 467 (2016)
      PubDate: 2016-06-03
      DOI: 10.1038/nrn.2016.51
      Issue No: Vol. 17, No. 8 (2016)
       
  • Synaptic plasticity in the anterior cingulate cortex in acute and chronic
           pain
    • Authors: Tim V. P. Bliss, Graham L. Collingridge, Bong-Kiun Kaang, Min Zhuo
      Pages: 485 - 496
      Abstract: The anterior cingulate cortex (ACC) is activated in both acute and chronic pain. In this Review, we discuss increasing evidence from rodent studies that ACC activation contributes to chronic pain states and describe several forms of synaptic plasticity that may underlie this effect. In particular,
      Citation: Nature Reviews Neuroscience 17, 485 (2016)
      PubDate: 2016-06-16
      DOI: 10.1038/nrn.2016.68
      Issue No: Vol. 17, No. 8 (2016)
       
  • Integrating neuroimmune systems in the neurobiology of depression
    • Authors: Eric S. Wohleb, Tina Franklin, Masaaki Iwata, Ronald S. Duman
      Pages: 497 - 511
      Abstract: Data from clinical and preclinical studies indicate that immune dysregulation, specifically of inflammatory processes, is associated with symptoms of major depressive disorder (MDD). In particular, increased levels of circulating pro-inflammatory cytokines and concomitant activation of brain-resident microglia can lead to depressive behavioural symptoms. Repeated exposure
      Citation: Nature Reviews Neuroscience 17, 497 (2016)
      PubDate: 2016-06-09
      DOI: 10.1038/nrn.2016.69
      Issue No: Vol. 17, No. 8 (2016)
       
  • Over the river, through the woods: cognitive maps in the hippocampus and
           orbitofrontal cortex
    • Authors: Andrew M. Wikenheiser, Geoffrey Schoenbaum
      Pages: 513 - 523
      Abstract: The hippocampus and the orbitofrontal cortex (OFC) both have important roles in cognitive processes such as learning, memory and decision making. Nevertheless, research on the OFC and hippocampus has proceeded largely independently, and little consideration has been given to the importance of interactions between these
      Citation: Nature Reviews Neuroscience 17, 513 (2016)
      PubDate: 2016-06-03
      DOI: 10.1038/nrn.2016.56
      Issue No: Vol. 17, No. 8 (2016)
       
  • Dysregulation of the dopamine system in the pathophysiology of
           schizophrenia and depression
    • Authors: Anthony A. Grace
      Pages: 524 - 532
      Abstract: The dopamine system is unique among the brain's modulatory systems in that it has discrete projections to specific brain regions involved in motor behaviour, cognition and emotion. Dopamine neurons exhibit several activity patterns — including tonic and phasic firing — that are determined by a
      Citation: Nature Reviews Neuroscience 17, 524 (2016)
      PubDate: 2016-06-03
      DOI: 10.1038/nrn.2016.57
      Issue No: Vol. 17, No. 8 (2016)
       
  • Emotion regulation involves both model-based and model-free processes
    • Pages: 532 - 532
      Abstract: In response to our Opinion article (The neural bases of emotion regulation. Nat. Rev. Neurosci.16, 693–700 (2015)) Raio et al. (Classifying emotion regulation strategies. Nat. Rev. Neurosci.http://dx.doi.org/10.1038/nrn.2016.78 (2016)) state that “linking emotion regulation to computational decision making is
      Citation: Nature Reviews Neuroscience 17, 532 (2016)
      PubDate: 2016-06-09
      DOI: 10.1038/nrn.2016.79
      Issue No: Vol. 17, No. 8 (2016)
       
  • Classifying emotion regulation strategies
    • Authors: Candace M. Raio, Elizabeth V. Goldfarb, Karolina M. Lempert, Peter Sokol-Hessner
      Pages: 532 - 532
      Abstract: In their recent article (The neural bases of emotion regulation. Nat. Rev. Neurosci. 16, 693–700 (2015)), Etkin, Büchel and Gross proposed testing emotion regulation using computational approaches that are anchored in reinforcement learning. Their framework classifies emotion regulation strategies as model-based (MB; computationally
      Citation: Nature Reviews Neuroscience 17, 532 (2016)
      PubDate: 2016-06-09
      DOI: 10.1038/nrn.2016.78
      Issue No: Vol. 17, No. 8 (2016)
       
 
 
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