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Nature Reviews Neuroscience    [147 followers]  Follow    
  Full-text available via subscription Subscription journal
     ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
     Published by Nature Publishing Group Homepage  [108 journals]   [SJR: 8.65]   [H-I: 232]
  • Neurodegeneration: Ageing neurons need REST
    • Authors: Katherine Whalley
      Pages: 279 - 279
      Abstract: The transcription factor REST has a neuroprotective role in the healthy ageing brain that is disrupted in Alzheimer's disease.
      Citation: Nature Reviews Neuroscience 15, 279 (2014)
      PubDate: 2014-04-03
      DOI: 10.1038/nrn3728
      Issue No: Vol. 15, No. 5 (2014)
       
  • Synaptic plasticity: Microglial cell-mediated depression
    • Authors: Darran Yates
      Pages: 280 - 281
      Abstract: Activation of microglial complement receptor 3 by an inflammatory stimulus in the presence of hypoxia induces long-term depression of synaptic transmission in the hippocampus.
      Citation: Nature Reviews Neuroscience 15, 280 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3733
      Issue No: Vol. 15, No. 5 (2014)
       
  • Neurodevelopment: Pruning: a class I act
    • Authors: Leonie Welberg
      Pages: 280 - 281
      Abstract: Neuronally expressed major histocompatibility complex class I molecule H2-Db regulates structural and functional plasticity at retinogeniculate synapses.
      Citation: Nature Reviews Neuroscience 15, 280 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3732
      Issue No: Vol. 15, No. 5 (2014)
       
  • A blood test for Alzheimer's disease'
    • Authors: Leonie Welberg
      Pages: 280 - 280
      Abstract: A recent study has identified a potential blood-based biomarker for Alzheimer's disease.
      Citation: Nature Reviews Neuroscience 15, 280 (2014)
      PubDate: 2014-03-19
      DOI: 10.1038/nrn3726
      Issue No: Vol. 15, No. 5 (2014)
       
  • Olfaction: The nose knows one trillion smells
    • Authors: Natasha Bray
      Pages: 281 - 281
      Abstract: How many smells can a person discriminate' Bushdid et al. created mixtures comprising 10, 20 or 30 components from a collection of 128 different odorous molecules and asked participants to identify the 'odd-one-out' from three mixtures. Each participant completed 264 of these tests in
      Citation: Nature Reviews Neuroscience 15, 281 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3736
      Issue No: Vol. 15, No. 5 (2014)
       
  • Learning and memory: The hippocampus encodes objects in time
    • Authors: Natasha Bray
      Pages: 281 - 281
      Abstract: The hippocampus has an essential role in episodic memory, but its encoding mechanisms remain unclear. Two studies used pattern similarity analysis of functional MRI data from tasks involving learning objects in temporal orders. Hsieh et al. found that hippocampal activity patterns contained information about
      Citation: Nature Reviews Neuroscience 15, 281 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3735
      Issue No: Vol. 15, No. 5 (2014)
       
  • Sensory processing: 'Seeing' bodies via sounds
    • Authors: Natasha Bray
      Pages: 281 - 281
      Abstract: In sighted people, seeing human bodies or body parts selectively activates the extrastriate body area (EBA) of the visual cortex; however, it is not known whether EBA activation and hence development of a body-image network occurs in the absence of visual stimuli. Striem-Amit and Amedi
      Citation: Nature Reviews Neuroscience 15, 281 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3734
      Issue No: Vol. 15, No. 5 (2014)
       
  • Gap junctions: Inputs alter coupling strength
    • Authors: Leonie Welberg
      Pages: 282 - 283
      Abstract: Both GABAergic and glutamatergic projections can modulate the strength of electrical coupling between inferior olive neurons and alter neuron synchronization in the cerebellar inferior olive.
      Citation: Nature Reviews Neuroscience 15, 282 (2014)
      PubDate: 2014-04-17
      DOI: 10.1038/nrn3741
      Issue No: Vol. 15, No. 5 (2014)
       
  • Learning and memory: Out of body, out of mind
    • Authors: Leonie Welberg
      Pages: 282 - 283
      Abstract: An event that is experienced from an 'out-of-body' perspective is remembered less well and its recall does not induce the usual pattern of hippocampal activation.
      Citation: Nature Reviews Neuroscience 15, 282 (2014)
      PubDate: 2014-04-03
      DOI: 10.1038/nrn3727
      Issue No: Vol. 15, No. 5 (2014)
       
  • Sensory processing: Shifting states
    • Authors: Leonie Welberg
      Pages: 283 - 283
      Abstract: Cortical neurons show irregular spiking activity during rest and sensory stimulation. This could mean that the cortex is in an asynchronous cortical state in which the membrane potential (Vm) is just below the spike threshold and irregular spiking results from converging uncorrelated
      Citation: Nature Reviews Neuroscience 15, 283 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3740
      Issue No: Vol. 15, No. 5 (2014)
       
  • Transporters: Channelling seizure susceptibility
    • Authors: Leonie Welberg
      Pages: 283 - 283
      Abstract: Mice lacking K+-Cl− cotransporter 2 (KCC2; also known as SLC12A5) have seizures. Investigating possible KCC2 mutations in human families with seizure disorders, the authors identified a variant, KCC2-R952H, that was associated with febrile seizures. Mouse cortical neurons transfected with KCC2-R952H
      Citation: Nature Reviews Neuroscience 15, 283 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3739
      Issue No: Vol. 15, No. 5 (2014)
       
  • Neuroimaging: Functional networks are short-lived
    • Authors: Leonie Welberg
      Pages: 283 - 283
      Abstract: Functional MRI (fMRI) studies have shown that activity in resting-state networks (RSNs) fluctuates over seconds. To assess functional connectivity with a temporal resolution higher than that of fMRI, Baker et al. used a novel, magnetoencephalography-based approach. This revealed several brain 'states' that were each
      Citation: Nature Reviews Neuroscience 15, 283 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3738
      Issue No: Vol. 15, No. 5 (2014)
       
  • Neurophysiology: Pericytes set the tone
    • Authors: Leonie Welberg
      Pages: 283 - 283
      Abstract: Do pericytes have a role in regulating cerebral blood flow' Attwell and colleagues showed that in rat cerebellar slices, glutamate application triggered dilation of pericytes and capillaries. Whisker pad stimulation evoked pericyte dilation and then capillary dilation in the somatosensory cortex, particularly at locations apposed
      Citation: Nature Reviews Neuroscience 15, 283 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3737
      Issue No: Vol. 15, No. 5 (2014)
       
  • Nuclear and cytosolic JNK signalling in neurons
    • Authors: Eleanor T. Coffey
      Pages: 285 - 299
      Abstract: It has been over 20 years since JUN amino-terminal kinases (JNKs) were identified as protein kinases that are strongly activated by cellular stress and that have a key role in apoptosis. Examination of Jnk-knockout mice and characterization of JNK behaviour in neuronal cells has
      Citation: Nature Reviews Neuroscience 15, 285 (2014)
      PubDate: 2014-04-17
      DOI: 10.1038/nrn3729
      Issue No: Vol. 15, No. 5 (2014)
       
  • Microglia and brain macrophages in the molecular age: from origin to
           neuropsychiatric disease
    • Authors: Marco Prinz, Josef Priller
      Pages: 300 - 312
      Abstract: Mononuclear phagocytic cells in the CNS used to be defined according to their anatomical location and surface marker expression. Recently, this concept has been challenged by the results of developmental and gene expression profiling studies that have used novel molecular biological tools to unravel the
      Citation: Nature Reviews Neuroscience 15, 300 (2014)
      PubDate: 2014-04-09
      DOI: 10.1038/nrn3722
      Issue No: Vol. 15, No. 5 (2014)
       
  • Restoring sensorimotor function through intracortical interfaces: progress
           and looming challenges
    • Authors: Sliman J. Bensmaia, Lee E. Miller
      Pages: 313 - 325
      Abstract: The loss of a limb or paralysis resulting from spinal cord injury has devastating consequences on quality of life. One approach to restoring lost sensory and motor abilities in amputees and patients with tetraplegia is to supply them with implants that provide a direct interface
      Citation: Nature Reviews Neuroscience 15, 313 (2014)
      PubDate: 2014-04-17
      DOI: 10.1038/nrn3724
      Issue No: Vol. 15, No. 5 (2014)
       
  • Astrocyte Ca2+ signalling: an unexpected complexity
    • Authors: Andrea Volterra, Nicolas Liaudet, Iaroslav Savtchouk
      Pages: 327 - 335
      Abstract: Astrocyte Ca2+ signalling has been proposed to link neuronal information in different spatial–temporal dimensions to achieve a higher level of brain integration. However, some discrepancies in the results of recent studies challenge this view and highlight key insufficiencies in our current understanding. In
      Citation: Nature Reviews Neuroscience 15, 327 (2014)
      PubDate: 2014-04-17
      DOI: 10.1038/nrn3725
      Issue No: Vol. 15, No. 5 (2014)
       
  • How does the bilingual experience sculpt the brain'
    • Authors: Albert Costa, Núria Sebastián-Gallés
      Pages: 336 - 345
      Abstract: The ability to speak two languages often marvels monolinguals, although bilinguals report no difficulties in achieving this feat. Here, we examine how learning and using two languages affect language acquisition and processing as well as various aspects of cognition. We do so by addressing three
      Citation: Nature Reviews Neuroscience 15, 336 (2014)
      PubDate: 2014-04-17
      DOI: 10.1038/nrn3709
      Issue No: Vol. 15, No. 5 (2014)
       
 
 
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