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Nature Reviews : Neuroscience

[119 followers] Follow
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ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
Published by Nature Publishing Group

[134 journals]

Neuroendocrinology: Hypothalamic self-tuning to stress
- Authors: Leonie Welberg
  Pages: 377 - 377
  Abstract: Stress induces a metaplastic signal at GABA synapses in the paraventricular nucleus of the hypothalamus that can account for both the early sensitization and the delayed inhibition of responses to subsequent stressors.
  Citation: Nature Reviews Neuroscience 14, 377 (2013)
  PubDate: 2013-05-02
  DOI: 10.1038/nrn3508
  Issue No: Vol. 14, No. 6 (2013)
Sensory systems: Encoding aversion
- Authors: Katherine Whalley
  Pages: 378 - 379
  Abstract: The gene encoding trace amine-associated receptor 4 (TAAR4) is essential for the detection of aversive odours in mice, demonstrating the importance of an individual receptor gene for odour perception.
  Citation: Nature Reviews Neuroscience 14, 378 (2013)
  PubDate: 2013-05-15
  DOI: 10.1038/nrn3518
  Issue No: Vol. 14, No. 6 (2013)
Synaptic transmission: Summer blues
- Authors: Monica Hoyos Flight
  Pages: 378 - 379
  Abstract: Exposure to different day–night cycles leads to a change in the expression of neurotransmitters and behaviour in adult rats.
  Citation: Nature Reviews Neuroscience 14, 378 (2013)
  PubDate: 2013-05-15
  DOI: 10.1038/nrn3517
  Issue No: Vol. 14, No. 6 (2013)
Pain: Feeling the heat (and cold)
- Authors: Sian Lewis
  Pages: 378 - 378
  Abstract: A new study shows that a subtype of dorsal root ganglion sensory neurons that express calcitonin gene-related peptide-α are involved in sensing heat but also indirectly modulate cold-sensing neurons.
  Citation: Nature Reviews Neuroscience 14, 378 (2013)
  PubDate: 2013-05-02
  DOI: 10.1038/nrn3507
  Issue No: Vol. 14, No. 6 (2013)
Visual processing: Area V4 in motion
- Authors: Leonie Welberg
  Pages: 379 - 379
  Abstract: Although visual area V4 is known to process object colour and form, it also contains motion-direction sensitive neurons. The authors investigated the functional organization of directional responses in this area using optical imaging and single-cell recording in monkeys. The neurons that respond to stimuli moving
  Citation: Nature Reviews Neuroscience 14, 379 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3522
  Issue No: Vol. 14, No. 6 (2013)
Neuroimaging: Evaluating ads with fMRI
- Authors: Leonie Welberg
  Pages: 379 - 379
  Abstract: This study used functional MRI (fMRI) to assess smokers' responses to the content of anti-smoking television advertisements. Advertisements with strong arguments (as rated by smokers) evoked greater responses in the dorsomedial prefrontal cortex (dmPFC) than those with weaker arguments, and dmPFC activation negatively correlated with
  Citation: Nature Reviews Neuroscience 14, 379 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3521
  Issue No: Vol. 14, No. 6 (2013)
Psychiatric disorders: Astrocytic ATP in depression
- Authors: Leonie Welberg
  Pages: 379 - 379
  Abstract: Depression has been associated with glial dysfunction, but the underlying mechanisms have remained elusive. Here, mice that developed depression-like behaviour after chronic social defeat stress had reduced ATP levels in the prefrontal cortex (PFC) and hippocampus compared with non-depressed and control mice. Central or peripheral
  Citation: Nature Reviews Neuroscience 14, 379 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3520
  Issue No: Vol. 14, No. 6 (2013)
Metabolism: Flavours of value
- Authors: Leonie Welberg
  Pages: 379 - 379
  Abstract: Animals can form preferences for flavours previously paired with another, undetectable, calorie-rich substance, suggesting the formation of associations between flavours and nutritional value. The authors showed that in humans, increases in plasma glucose levels after ingestion of a flavour paired with the carbohydrate maltodextrin correlated
  Citation: Nature Reviews Neuroscience 14, 379 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3519
  Issue No: Vol. 14, No. 6 (2013)
Learning and memory: Learning with peaks and troughs
- Authors: Leonie Welberg
  Pages: 380 - 381
  Abstract: Circadian corticosterone fluctuations support learning and memory by promoting learning-associated spine formation and elimination.
  Citation: Nature Reviews Neuroscience 14, 380 (2013)
  PubDate: 2013-05-09
  DOI: 10.1038/nrn3515
  Issue No: Vol. 14, No. 6 (2013)
Spatial processing: Place cells as route planners
- Authors: Darran Yates
  Pages: 380 - 381
  Abstract: Rats may use sequences of activity in hippocampal place cells to plan a route to a remembered location.
  Citation: Nature Reviews Neuroscience 14, 380 (2013)
  PubDate: 2013-05-09
  DOI: 10.1038/nrn3514
  Issue No: Vol. 14, No. 6 (2013)
Techniques: CLARITY in imaging
- Authors: Katherine Whalley
  Pages: 380 - 380
  Abstract: Obtaining high-resolution structural and molecular information from intact brain tissue is a key goal, but existing techniques face several limitations. In a new approach, named CLARITY by the authors, an intact mouse brain tissue was hybridized with a hydrogel to preserve its structure and then
  Citation: Nature Reviews Neuroscience 14, 380 (2013)
  PubDate: 2013-05-09
  DOI: 10.1038/nrn3513
  Issue No: Vol. 14, No. 6 (2013)
Neural transplantation: Reprogramming fibroblasts to OPCs
- Authors: Katherine Whalley
  Pages: 380 - 380
  Abstract: Cell transplantation has potential as a treatment strategy for myelin disorders; however, identifying a source of myelinating cells is essential. The authors exposed mouse fibroblasts to three key transcription factors, generating an expandable population of induced oligodendrocyte progenitor cells (OPCs). When transplanted into forebrain slices
  Citation: Nature Reviews Neuroscience 14, 380 (2013)
  PubDate: 2013-05-09
  DOI: 10.1038/nrn3512
  Issue No: Vol. 14, No. 6 (2013)
Neuroimaging: Detecting consciousness in infants
- Authors: Katherine Whalley
  Pages: 380 - 380
  Abstract: It is hard to demonstrate the presence of conscious processing in pre-verbal infants, but objective measures of consciousness might overcome this problem. The authors recorded event-related potentials in 5-, 12- and 15-month-old infants during trials in which a briefly displayed image of a face was
  Citation: Nature Reviews Neuroscience 14, 380 (2013)
  PubDate: 2013-05-09
  DOI: 10.1038/nrn3511
  Issue No: Vol. 14, No. 6 (2013)
Circadian rhythms: Temperature training
- Authors: Katherine Whalley
  Pages: 380 - 380
  Abstract: The circadian clock is entrained by daily light fluctuations, but daily temperature fluctuations can also entrain circadian rhythms through an as yet poorly understood mechanism. Here, the authors show that the thermosensory ion channel transient receptor potential A1 (TRPA1) is expressed in the lateral posterior
  Citation: Nature Reviews Neuroscience 14, 380 (2013)
  PubDate: 2013-05-09
  DOI: 10.1038/nrn3510
  Issue No: Vol. 14, No. 6 (2013)
Auditory system: Sound choices
- Authors: Darran Yates
  Pages: 381 - 381
  Abstract: Corticostriatal neuronal activity in the auditory cortex is necessary to drive behavioural choices in an auditory discrimination task.
  Citation: Nature Reviews Neuroscience 14, 381 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3523
  Issue No: Vol. 14, No. 6 (2013)
NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease
- Authors: Pierre Paoletti|Camilla Bellone|Qiang Zhou
  Pages: 383 - 400
  Abstract: NMDA receptors (NMDARs) are glutamate-gated ion channels and are crucial for neuronal communication. NMDARs form tetrameric complexes that consist of several homologous subunits. The subunit composition of NMDARs is plastic, resulting in a large number of receptor subtypes. As each receptor subtype has distinct biophysical,
  Citation: Nature Reviews Neuroscience 14, 383 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3504
  Issue No: Vol. 14, No. 6 (2013)
BDNF-based synaptic repair as a disease-modifying strategy for neurodegenerative diseases
- Authors: Bai Lu|Guhan Nagappan|Xiaoming Guan|Pradeep J. Nathan|Paul Wren
  Pages: 401 - 416
  Abstract: Increasing evidence suggests that synaptic dysfunction is a key pathophysiological hallmark in neurodegenerative disorders, including Alzheimer's disease. Understanding the role of brain-derived neurotrophic factor (BDNF) in synaptic plasticity and synaptogenesis, the impact of the BDNF Val66Met polymorphism in Alzheimer's disease-relevant endophenotypes — including episodic
  Citation: Nature Reviews Neuroscience 14, 401 (2013)
  PubDate: 2013-05-15
  DOI: 10.1038/nrn3505
  Issue No: Vol. 14, No. 6 (2013)
The contextual brain: implications for fear conditioning, extinction and psychopathology
- Authors: Stephen Maren|K. Luan Phan|Israel Liberzon
  Pages: 417 - 428
  Abstract: Contexts surround and imbue meaning to events; they are essential for recollecting the past, interpreting the present and anticipating the future. Indeed, the brain's capacity to contextualize information permits enormous cognitive and behavioural flexibility. Studies of Pavlovian fear conditioning and extinction in rodents and humans
  Citation: Nature Reviews Neuroscience 14, 417 (2013)
  PubDate: 2013-05-02
  DOI: 10.1038/nrn3492
  Issue No: Vol. 14, No. 6 (2013)
Bridging the gap between theories of sensory cue integration and the physiology of multisensory neurons
- Authors: Christopher R. Fetsch|Gregory C. DeAngelis|Dora E. Angelaki
  Pages: 429 - 442
  Abstract: The richness of perceptual experience, as well as its usefulness for guiding behaviour, depends on the synthesis of information across multiple senses. Recent decades have witnessed a surge in our understanding of how the brain combines sensory cues. Much of this research has been guided
  Citation: Nature Reviews Neuroscience 14, 429 (2013)
  PubDate: 2013-05-20
  DOI: 10.1038/nrn3503
  Issue No: Vol. 14, No. 6 (2013)
Emerging roles of astrocytes in neural circuit development
- Authors: Laura E. Clarke|Ben A. Barres
  Pages: 442 - 442
  Abstract: Nature Reviews Neuroscience14, 311–321 (2013)In this article, the corresponding author was listed incorrectly. The corresponding author is Laura E. Clarke, e-mail: lclarke2@stanford.edu. This has been corrected in the online version of the article.
  Citation: Nature Reviews Neuroscience 14, 442 (2013)
  PubDate: 2013-05-02
  DOI: 10.1038/nrn3506
  Issue No: Vol. 14, No. 6 (2013)
Power failure: why small sample size undermines the reliability of neuroscience
- Authors: Katherine S. Button|John P. A. Ioannidis|Claire Mokrysz|Brian A. Nosek|Jonathan Flint|Emma S. J. Robinson|Marcus R. Munafó
  Pages: 442 - 442
  Abstract: Nature Reviews Neuroscience14, 365–376 (2013)On page 366 of this article, the definition of R should have read: "R is the pre-study odds (that is, the odds that a probed effect is indeed non-null among the effects being probed)". This has been corrected
  Citation: Nature Reviews Neuroscience 14, 442 (2013)
  PubDate: 2013-04-15
  DOI: 10.1038/nrn3502
  Issue No: Vol. 14, No. 6 (2013)
Sleep and the single neuron: the role of global slow oscillations in individual cell rest
- Authors: Vladyslav V. Vyazovskiy|Kenneth D. Harris
  Pages: 443 - 451
  Abstract: Sleep is universal in animals, but its specific functions remain elusive. We propose that sleep's primary function is to allow individual neurons to perform prophylactic cellular maintenance. Just as muscle cells must rest after strenuous exercise to prevent long-term damage, brain cells must rest after
  Citation: Nature Reviews Neuroscience 14, 443 (2013)
  PubDate: 2013-05-02
  DOI: 10.1038/nrn3494
  Issue No: Vol. 14, No. 6 (2013)