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Journal Cover Nature Reviews Neuroscience
  [SJR: 21.499]   [H-I: 309]   [282 followers]  Follow
    
   Full-text available via subscription Subscription journal  (Not entitled to full-text)
   ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
   Published by NPG Homepage  [127 journals]
  • The contribution of neuroethics to international brain research
           initiatives
    • Authors: Kathinka Evers
      Pages: 1 - 2
      Abstract: Neuroethics research can contribute a level of conceptual clarity to international brain research initiatives that is essential for their ethics management as well as for the interpretations, applications and management of their emerging neuroscientific findings.
      Citation: Nature Reviews Neuroscience 18, 1 (2017)
      PubDate: 2016-10-27
      DOI: 10.1038/nrn.2016.143
      Issue No: Vol. 18, No. 1 (2016)
       
  • Psychiatric disorders: Age-dependent auditory abnormalities
    • Authors: Natasha Bray
      Pages: 3 - 3
      Abstract: Deletion of Dgcr8 in 22q11.2 deletion syndrome leads to decreased processing of miR-338-3p, leading to an upregulation of thalamic dopamine D2 receptors and auditory thalamocortical deficits that might be associated with antipsychotic-sensitive auditory hallucinations.
      Citation: Nature Reviews Neuroscience 18, 3 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.168
      Issue No: Vol. 18, No. 1 (2016)
       
  • Glia: An astrocytic influence
    • Authors: Darran Yates
      Pages: 4 - 4
      Abstract: How astrocytic Ca2+ signalling interacts with neural activity in vivo and affects behaviour is not well understood. A new study in Drosophila melanogaster found that astrocytic knockdown of a transient receptor potential cation channel inhibited somatic astrocytic Ca2+ transients
      Citation: Nature Reviews Neuroscience 18, 4 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.173
      Issue No: Vol. 18, No. 1 (2016)
       
  • Cell biology of the neuron: Endocytic mediators
    • Authors: Darran Yates
      Pages: 4 - 4
      Abstract: Whether actin has a role in endocytosis in mammalian cells is unclear. Wu et al. showed that, in mice, knockout of the β-actin gene or γ-actin gene impaired various types of endocytosis in calyx-type and hippocampal synapses. The deficits observed in hippocampal boutons could
      Citation: Nature Reviews Neuroscience 18, 4 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.172
      Issue No: Vol. 18, No. 1 (2016)
       
  • Learning and memory: The cannabinoid connection
    • Authors: Darran Yates
      Pages: 4 - 4
      Abstract: How acute changes in the activity of neuronal mitochondrial affect learning and memory is unclear. By precluding mitochondrial localization of cannabinoid receptor 1 (CB1) in the mouse hippocampus, the authors prevented CB1-agonist-induced inhibition of excitatory transmission in hippocampal slices and of the poor performance of
      Citation: Nature Reviews Neuroscience 18, 4 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.171
      Issue No: Vol. 18, No. 1 (2016)
       
  • Glia: Glial messenging
    • Authors: Darran Yates
      Pages: 4 - 4
      Abstract: A new study provides evidence for a glia-mediated form of long-term potentiation (LTP) in the rat spinal cord. Activation of astrocytes and microglia induced LTP at spinal C-fibre synapses on lamina I neurons in vitro. Blocking glial metabolism or signalling induced by D-serine,
      Citation: Nature Reviews Neuroscience 18, 4 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.170
      Issue No: Vol. 18, No. 1 (2016)
       
  • Neural development: Balancing the pruning programmes
    • Authors: Sian Lewis
      Pages: 4 - 4
      Abstract: The genetic programmes involved in axonal pruning during development are poorly elucidated but are shown to involve a balance between the anti-apoptotic protein DUSP16 and the pro-degenerative protein PUMA.
      Citation: Nature Reviews Neuroscience 18, 4 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.169
      Issue No: Vol. 18, No. 1 (2016)
       
  • Systems neuroscience: Opening the gait
    • Authors: Sian Lewis
      Pages: 4 - 4
      Abstract: A brain–spine interface that uses decoded neural activity from motor cortex delivered to an electrical stimulation system in the spine was used to restore locomotor function in a monkey whose leg was paralyzed by spinal injury.
      Citation: Nature Reviews Neuroscience 18, 4 (2017)
      PubDate: 2016-12-01
      DOI: 10.1038/nrn.2016.166
      Issue No: Vol. 18, No. 1 (2016)
       
  • Perception: Coding for choice
    • Authors: Katherine Whalley
      Pages: 5 - 5
      Abstract: The mechanisms by which sensory representations are transformed to enable perception and decision making are unknown. Rossi-Pool et al. recorded from neurons in the cortex of monkeys performing a task that required them to decide whether pairs of vibrotactile stimulus patterns were the same
      Citation: Nature Reviews Neuroscience 18, 5 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.177
      Issue No: Vol. 18, No. 1 (2016)
       
  • Synaptic transmission: Separating transmission modes
    • Authors: Katherine Whalley
      Pages: 5 - 5
      Abstract: The extent to which spontaneous and evoked neurotransmission are spatially segregated within a synapse is unclear. Using a fluorescent calcium indicator to visualize activity in individual synapses, the authors found that most synapses in dissociated hippocampal cultures exhibit both spontaneous and evoked neurotransmission; however, unique
      Citation: Nature Reviews Neuroscience 18, 5 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.176
      Issue No: Vol. 18, No. 1 (2016)
       
  • Metabolism: A rapid satiety circuit
    • Authors: Katherine Whalley
      Pages: 5 - 5
      Abstract: Current models of hypothalamic function cannot account for the rapid induction of satiety: activation of arcuate nucleus pro-opiomelanocortin (POMC)-expressing neurons (ARCPOMC neurons) only reduces hunger after several hours. The authors showed that manipulation of a population of glutamatergic ARC neurons rapidly alters feeding
      Citation: Nature Reviews Neuroscience 18, 5 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.175
      Issue No: Vol. 18, No. 1 (2016)
       
  • Neurodegenerative disease: Probing prions
    • Authors: Katherine Whalley
      Pages: 5 - 5
      Abstract: It has been hypothesized that the spread of misfolded proteins underlies patterns of neurodegeneration. Using a highly sensitive detection method, Alibhai et al. observed widespread early distribution of prion protein 'seeds' in a mouse model of prion disease but no correlation between the regions
      Citation: Nature Reviews Neuroscience 18, 5 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.174
      Issue No: Vol. 18, No. 1 (2016)
       
  • Stress, glucocorticoids and memory: implications for treating fear-related
           disorders
    • Authors: Dominique de Quervain, Lars Schwabe, Benno Roozendaal
      Pages: 7 - 19
      Abstract: Glucocorticoid stress hormones are crucially involved in modulating mnemonic processing of emotionally arousing experiences. They enhance the consolidation of new memories, including those that extinguish older memories, but impair the retrieval of information stored in long-term memory. As strong aversive memories lie at the core
      Citation: Nature Reviews Neuroscience 18, 7 (2017)
      PubDate: 2016-11-24
      DOI: 10.1038/nrn.2016.155
      Issue No: Vol. 18, No. 1 (2016)
       
  • Structural plasticity and reorganisation in chronic pain
    • Authors: Rohini Kuner, Herta Flor
      Pages: 20 - 30
      Abstract: Chronic pain is not simply a temporal continuum of acute pain. Studies on functional plasticity in neural circuits of pain have provided mechanistic insights and linked various modulatory factors to a change in perception and behaviour. However, plasticity also occurs in the context of structural
      Citation: Nature Reviews Neuroscience 18, 20 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.162
      Issue No: Vol. 18, No. 1 (2016)
       
  • Functional diversity of astrocytes in neural circuit regulation
    • Authors: Lucile Ben Haim, David H. Rowitch
      Pages: 31 - 41
      Abstract: Although it is well established that all brain regions contain various neuronal subtypes with different functions, astrocytes have traditionally been thought to be homogenous. However, recent evidence has shown that astrocytes in the mammalian CNS display distinct inter- and intra-regional features, as well as functional
      Citation: Nature Reviews Neuroscience 18, 31 (2017)
      PubDate: 2016-12-01
      DOI: 10.1038/nrn.2016.159
      Issue No: Vol. 18, No. 1 (2016)
       
  • The neural and computational bases of semantic cognition
    • Authors: Matthew A. Lambon Ralph, Elizabeth Jefferies, Karalyn Patterson, Timothy T. Rogers
      Pages: 42 - 55
      Abstract: Semantic cognition refers to our ability to use, manipulate and generalize knowledge that is acquired over the lifespan to support innumerable verbal and non-verbal behaviours. This Review summarizes key findings and issues arising from a decade of research into the neurocognitive and neurocomputational underpinnings of
      Citation: Nature Reviews Neuroscience 18, 42 (2017)
      PubDate: 2016-11-24
      DOI: 10.1038/nrn.2016.150
      Issue No: Vol. 18, No. 1 (2016)
       
  • Towards a mechanistic understanding of the human subcortex
    • Authors: Birte U. Forstmann, Gilles de Hollander, Leendert van Maanen, Anneke Alkemade, Max C. Keuken
      Pages: 57 - 65
      Abstract: The human subcortex is a densely populated part of the brain, of which only 7% of the individual structures are depicted in standard MRI atlases. In vivo MRI of the subcortex is challenging owing to its anatomical complexity and its deep location in the
      Citation: Nature Reviews Neuroscience 18, 57 (2017)
      PubDate: 2016-12-15
      DOI: 10.1038/nrn.2016.163
      Issue No: Vol. 18, No. 1 (2016)
       
 
 
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