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Journal Cover Nature Reviews Neuroscience
   [247 followers]  Follow    
   Full-text available via subscription Subscription journal
     ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
     Published by Nature Publishing Group Homepage  [110 journals]   [SJR: 8.65]   [H-I: 232]
  • Neurodegenerative disease: New dimensions in Alzheimer's modelling
    • Authors: Katherine Whalley
      Pages: 765 - 765
      Abstract: A three-dimensional human cell culture model of Alzheimer's disease recapitulates both amyloid-β and tau pathology.
      Citation: Nature Reviews Neuroscience 15, 765 (2014)
      PubDate: 2014-10-30
      DOI: 10.1038/nrn3860
      Issue No: Vol. 15, No. 12 (2014)
       
  • Dendrites: Regenerating space
    • Authors: Darran Yates
      Pages: 766 - 767
      Abstract: Place-cell firing in mice can be accompanied by regenerative dendritic events, which predict some of the properties of place fields.
      Citation: Nature Reviews Neuroscience 15, 766 (2014)
      PubDate: 2014-11-20
      DOI: 10.1038/nrn3870
      Issue No: Vol. 15, No. 12 (2014)
       
  • GLIA: Oligodendrocytes rev up motor learning
    • Authors: Natasha Bray
      Pages: 766 - 767
      Abstract: New oligodendrocytes that are derived from oligodendrocyte-precursor cells and express myelin regulatory factor are important for the learning of novel motor skills.
      Citation: Nature Reviews Neuroscience 15, 766 (2014)
      PubDate: 2014-11-05
      DOI: 10.1038/nrn3864
      Issue No: Vol. 15, No. 12 (2014)
       
  • Learning and memory: A memorable double act
    • Authors: Leonie Welberg
      Pages: 767 - 767
      Abstract: During memory retrieval the hippocampus is required for the reactivation of cortical activity patterns that occurred during encoding, but artificial reactivation of the cortical representation of a memory alone is sufficient to drive recall.
      Citation: Nature Reviews Neuroscience 15, 767 (2014)
      PubDate: 2014-10-30
      DOI: 10.1038/nrn3859
      Issue No: Vol. 15, No. 12 (2014)
       
  • Psychiatric disorders: A feat of epigenetic engineering
    • Authors: Katherine Whalley
      Pages: 768 - 769
      Abstract: Study uses in vivo gene-specific chromatin remodelling to elucidate the role of Fosb in addiction- and depression-related changes in the brain.
      Citation: Nature Reviews Neuroscience 15, 768 (2014)
      PubDate: 2014-11-20
      DOI: 10.1038/nrn3869
      Issue No: Vol. 15, No. 12 (2014)
       
  • Neurobiology of reward: Great expectations
    • Authors: Sian Lewis
      Pages: 768 - 768
      Abstract: The placebo effect is a powerful example of how expectations can shape experiences. Patients with Parkinson's disease, who have substantial loss of midbrain dopamine neurons projecting to the striatum and prefrontal cortex, show motor improvements after placebo treatment, suggesting that expectation may induce dopamine release.
      Citation: Nature Reviews Neuroscience 15, 768 (2014)
      PubDate: 2014-11-12
      DOI: 10.1038/nrn3868
      Issue No: Vol. 15, No. 12 (2014)
       
  • Synaptic plasticity: Opening a closed window
    • Authors: Sian Lewis
      Pages: 768 - 768
      Abstract: The mechanisms controlling the opening and closing of critical periods is not known, but Bochner et al. found that in adult mice, genetic disruption of paired immunoglobulin-like receptor B (PirB) increased neural plasticity of the visual cortex following monocular deprivation. Furthermore, acute blockade of
      Citation: Nature Reviews Neuroscience 15, 768 (2014)
      PubDate: 2014-11-12
      DOI: 10.1038/nrn3867
      Issue No: Vol. 15, No. 12 (2014)
       
  • Neurodegenerative disorders: Tangled up
    • Authors: Sian Lewis
      Pages: 768 - 768
      Abstract: Alzheimer's disease is characterized by neurofibrillary tangles composed of aggregates of truncated and hyperphosphorylated tau protein, but the mechanisms of their formation are understood poorly. The authors showed that in a mouse model of Alzheimer's disease, deletion of asparagine endopeptidase (AEP; a lysosomal cysteine proteinase)
      Citation: Nature Reviews Neuroscience 15, 768 (2014)
      PubDate: 2014-11-12
      DOI: 10.1038/nrn3866
      Issue No: Vol. 15, No. 12 (2014)
       
  • Synaptic physiology: No clathrin required
    • Authors: Sian Lewis
      Pages: 768 - 768
      Abstract: Large endocytic vesicles are retrieved rapidly through ultrafast endocytosis, but their fate is unknown. Watanabe et al. used the 'flash and freeze' technique to show that at physiological temperatures, stimulation of mouse hippocampal neurons results in clathrin-independent formation of large endocytic vesicles, which transition
      Citation: Nature Reviews Neuroscience 15, 768 (2014)
      PubDate: 2014-11-12
      DOI: 10.1038/nrn3865
      Issue No: Vol. 15, No. 12 (2014)
       
  • Behavioural neuroscience: Socially interactive interneurons
    • Authors: Natasha Bray
      Pages: 768 - 769
      Abstract: A subpopulation of cortical neurons that express oxytocin receptors mediates female sociosexual behaviour in mice.
      Citation: Nature Reviews Neuroscience 15, 768 (2014)
      PubDate: 2014-10-30
      DOI: 10.1038/nrn3861
      Issue No: Vol. 15, No. 12 (2014)
       
  • Neurogenesis: Fat cells send messages to the brain
    • Authors: Leonie Welberg
      Pages: 769 - 769
      Abstract: The adipocyte-secreted protein adiponectin (ADN) has anti-inflammatory and antidiabetic peripheral effects, similarly to exercise. Investigating a possible link between the effects of exercise and ADN on the brain in mice, Yau et al. showed that ADN can pass the blood–brain barrier and that running
      Citation: Nature Reviews Neuroscience 15, 769 (2014)
      PubDate: 2014-11-20
      DOI: 10.1038/nrn3873
      Issue No: Vol. 15, No. 12 (2014)
       
  • Glia: Glial ankyrins function at the junction
    • Authors: Leonie Welberg
      Pages: 769 - 769
      Abstract: The mechanisms involved in the assembly and maintenance of paranodal axon–glial junctions that flank nodes of Ranvier are not completely understood. Rasband and colleagues showed that the scaffolding proteins ankyrin B (ANKB) and ankyrin G (ANKG) are enriched on the glial, rather than the neuronal
      Citation: Nature Reviews Neuroscience 15, 769 (2014)
      PubDate: 2014-11-20
      DOI: 10.1038/nrn3872
      Issue No: Vol. 15, No. 12 (2014)
       
  • Psychiatric disorders: GluN2B mediates ketamine's antidepressant effect
    • Authors: Leonie Welberg
      Pages: 769 - 769
      Abstract: The cellular mechanisms underlying the rapid antidepressant effects of the NMDA receptor (NMDAR) antagonist ketamine are not well understood. Miller et al. showed that mice lacking the NMDAR subunit GluN2B from principal cortical neurons showed reduced despair-like behaviour and that ketamine had no antidepressant
      Citation: Nature Reviews Neuroscience 15, 769 (2014)
      PubDate: 2014-11-20
      DOI: 10.1038/nrn3871
      Issue No: Vol. 15, No. 12 (2014)
       
  • Polyunsaturated fatty acids and their metabolites in brain function and
           disease
    • Authors: Richard P. Bazinet, Sophie Layé
      Pages: 771 - 785
      Abstract: The brain is highly enriched with fatty acids. These include the polyunsaturated fatty acids (PUFAs) arachidonic acid and docosahexaenoic acid, which are largely esterified to the phospholipid cell membrane. Once PUFAs are released from the membrane, they can participate in signal transduction, either directly or
      Citation: Nature Reviews Neuroscience 15, 771 (2014)
      PubDate: 2014-11-12
      DOI: 10.1038/nrn3820
      Issue No: Vol. 15, No. 12 (2014)
       
  • Programming of neural cells by (endo)cannabinoids: from physiological
           rules to emerging therapies
    • Authors: Mauro Maccarrone, Manuel Guzmán, Ken Mackie, Patrick Doherty, Tibor Harkany
      Pages: 786 - 801
      Abstract: Among the many signalling lipids, endocannabinoids are increasingly recognized for their important roles in neuronal and glial development. Recent experimental evidence suggests that, during neuronal differentiation, endocannabinoid signalling undergoes a fundamental switch from the prenatal determination of cell fate to the homeostatic regulation of synaptic
      Citation: Nature Reviews Neuroscience 15, 786 (2014)
      PubDate: 2014-11-20
      DOI: 10.1038/nrn3846
      Issue No: Vol. 15, No. 12 (2014)
       
  • The molecular bases of the suicidal brain
    • Authors: Gustavo Turecki
      Pages: 802 - 816
      Abstract: Suicide ranks among the leading causes of death around the world and takes a heavy emotional and public health toll on most societies. Both distal and proximal factors contribute to suicidal behaviour. Distal factors — such as familial and genetic predisposition, as well as early-life
      Citation: Nature Reviews Neuroscience 15, 802 (2014)
      PubDate: 2014-10-30
      DOI: 10.1038/nrn3839
      Issue No: Vol. 15, No. 12 (2014)
       
  • Expectation in perceptual decision making: neural and computational
           mechanisms
    • Authors: Christopher Summerfield, Floris P. de Lange
      Pages: 816 - 816
      Abstract: Nature Reviews Neuroscience15, 745–756 (2014)On page 746 of this article, the symbol ¬ in ¬R was missing in several places. This has been corrected in the online version.
      Citation: Nature Reviews Neuroscience 15, 816 (2014)
      PubDate: 2014-10-22
      DOI: 10.1038/nrn3863
      Issue No: Vol. 15, No. 12 (2014)
       
  • The role of orexin in motivated behaviours
    • Authors: Takeshi Sakurai
      Pages: 816 - 816
      Abstract: Nature Reviews Neuroscience15, 719–731 (2014)In Figure 1 and Figure 3 of this article, the excitatory effects of low pH and high CO2 levels on orexin neurons were incorrectly displayed as inhibitory. This has been corrected
      Citation: Nature Reviews Neuroscience 15, 816 (2014)
      PubDate: 2014-10-20
      DOI: 10.1038/nrn3862
      Issue No: Vol. 15, No. 12 (2014)
       
  • Neuroscience and education: myths and messages
    • Authors: Paul A. Howard-Jones
      Pages: 817 - 824
      Abstract: For several decades, myths about the brain — neuromyths — have persisted in schools and colleges, often being used to justify ineffective approaches to teaching. Many of these myths are biased distortions of scientific fact. Cultural conditions, such as differences in terminology and language, have
      Citation: Nature Reviews Neuroscience 15, 817 (2014)
      PubDate: 2014-10-15
      DOI: 10.1038/nrn3817
      Issue No: Vol. 15, No. 12 (2014)
       
  • The warrior in the machine: neuroscience goes to war
    • Authors: Irene Tracey, Rod Flower
      Pages: 825 - 834
      Abstract: Ever since Stone Age men discovered that knapping flint produced sharp stone edges that could be used in combat as well as for cooking and hunting, technological advances of all kinds have been adapted and adopted by the military.The opportunities provided by modern neuroscience are
      Citation: Nature Reviews Neuroscience 15, 825 (2014)
      PubDate: 2014-11-12
      DOI: 10.1038/nrn3835
      Issue No: Vol. 15, No. 12 (2014)
       
 
 
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