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Journal Cover Nature Reviews Neuroscience
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   Full-text available via subscription Subscription journal
     ISSN (Print) 1471-003X - ISSN (Online) 1471-0048
     Published by Nature Publishing Group Homepage  [110 journals]   [SJR: 8.65]   [H-I: 232]
  • Learning and memory: Uncoupling memory traces
    • Authors: Leonie Welberg
      Pages: 629 - 629
      Abstract: The emotional valence of a memory can be changed, and this probably involves a change in the connectivity between hippocampal and amygdalar memory traces.
      Citation: Nature Reviews Neuroscience 15, 629 (2014)
      PubDate: 2014-09-10
      DOI: 10.1038/nrn3828
      Issue No: Vol. 15, No. 10 (2014)
       
  • Neurodegenerative disease: Hypermethylation raises AD risk
    • Authors: Sian Lewis
      Pages: 630 - 630
      Abstract: Drugs that modify DNA methylation have been shown to alter Alzheimer's disease (AD) pathology in animal models. Two recent studies therefore investigated whether DNA methylation underlies some of the changes in gene expression that occur in AD, De Jager et al. performed gene discovery
      Citation: Nature Reviews Neuroscience 15, 630 (2014)
      PubDate: 2014-09-04
      DOI: 10.1038/nrn3825
      Issue No: Vol. 15, No. 10 (2014)
       
  • Pain: Inflammation and pain
    • Authors: Sian Lewis
      Pages: 630 - 630
      Abstract: Spinal cord injury (SCI) results in inflammatory changes in the brain, but whether these changes underlie the effects of SCI on cognition is not known. Wu et al. showed that mice with SCI had memory deficits and depression-like behaviour. These behavioural changes were associated
      Citation: Nature Reviews Neuroscience 15, 630 (2014)
      PubDate: 2014-09-04
      DOI: 10.1038/nrn3824
      Issue No: Vol. 15, No. 10 (2014)
       
  • Learning and memory: Childhood problems and solutions
    • Authors: Sian Lewis
      Pages: 630 - 630
      Abstract: As children grow up, they switch from procedure-based to memory-based strategies for problem solving. However, the changes in brain circuitry underlying this switch are unknown. In a functional MRI analysis of 7–9-year-old children who were asked to solve simple addition problems (such as 3 +
      Citation: Nature Reviews Neuroscience 15, 630 (2014)
      PubDate: 2014-09-04
      DOI: 10.1038/nrn3823
      Issue No: Vol. 15, No. 10 (2014)
       
  • Psychiatric disorders: Disrupted transmission
    • Authors: Darran Yates
      Pages: 630 - 631
      Abstract: Neurons derived from human induced pluripotent stem cells harbouring a mutation in disrupted in schizophrenia 1 exhibit synaptic deficits.
      Citation: Nature Reviews Neuroscience 15, 630 (2014)
      PubDate: 2014-09-04
      DOI: 10.1038/nrn3822
      Issue No: Vol. 15, No. 10 (2014)
       
  • Learning and memory: Consolidation of fear
    • Authors: Darran Yates
      Pages: 630 - 631
      Abstract: In mice, miR-34a-mediated downregulation of Notch signalling in the basolateral amygdala enables fear memory consolidation.
      Citation: Nature Reviews Neuroscience 15, 630 (2014)
      PubDate: 2014-08-28
      DOI: 10.1038/nrn3821
      Issue No: Vol. 15, No. 10 (2014)
       
  • Learning and memory: Putting limits on learning
    • Authors: Katherine Whalley
      Pages: 631 - 631
      Abstract: The existing properties of neurons in a network restrict its ability to learn to generate new activity patterns.
      Citation: Nature Reviews Neuroscience 15, 631 (2014)
      PubDate: 2014-09-10
      DOI: 10.1038/nrn3826
      Issue No: Vol. 15, No. 10 (2014)
       
  • Visual processing: Microcircuits unmasked
    • Authors: Darran Yates
      Pages: 632 - 632
      Abstract: In mouse primary visual cortex, subpopulations of layer six principal cells form distinct microcircuits that are involved in visual processing.
      Citation: Nature Reviews Neuroscience 15, 632 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3834
      Issue No: Vol. 15, No. 10 (2014)
       
  • Cognitive neuroscience: Telling the truth, honestly...
    • Authors: Sian Lewis
      Pages: 632 - 632
      Abstract: Although the prefrontal cortex (PFC) has been implicated in aspects of behaviour relating to honesty, the mechanisms and circuits involved are unknown. The authors tested the responses of people in games in which subjects had to decide between self-interest and honesty. People with lesions to
      Citation: Nature Reviews Neuroscience 15, 632 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3833
      Issue No: Vol. 15, No. 10 (2014)
       
  • Cellular neurophysiology: Clearing away the debris
    • Authors: Sian Lewis
      Pages: 632 - 632
      Abstract: Damaged mitochondria are cleared from neurons by mitophagy. At the soma, this process is mediated by lysosomes and requires two Parkinson's disease-related proteins, parkin and PINK1. However, it remains controversial whether the same mechanisms operate in distal axons where lysosomes are sparse. The authors showed
      Citation: Nature Reviews Neuroscience 15, 632 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3832
      Issue No: Vol. 15, No. 10 (2014)
       
  • Genes and disease: Schwann cells keep axons healthy
    • Authors: Sian Lewis
      Pages: 632 - 632
      Abstract: Charcot-Marie-Tooth disease 1A (CMT1A) is an inherited neuropathy caused by duplication of the gene encoding peripheral myelin protein 22 (PMP22). In this study, PMP22 duplication in rodents caused defects in Schwann cell differentiation in early postnatal development, which persisted into adulthood. This abnormal Schwann
      Citation: Nature Reviews Neuroscience 15, 632 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3831
      Issue No: Vol. 15, No. 10 (2014)
       
  • Neurological disorders: Telomeres and depression
    • Authors: Sian Lewis
      Pages: 632 - 632
      Abstract: Studies of a link between reduced telomere length and depression and/or anxiety disorders have produced conflicting results. A recent large-scale survey of health and nutrition of US civilians found that women (but not men) with anxiety disorders had shorter telomeres than controls. Both men and
      Citation: Nature Reviews Neuroscience 15, 632 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3830
      Issue No: Vol. 15, No. 10 (2014)
       
  • The Kavli prize winners
    • Pages: 633 - 636
      Abstract: Interviews with this year's winners of the Kavli prize in neuroscience, Brenda Milner, John O'Keefe and Marcus Raichle.
      Citation: Nature Reviews Neuroscience 15, 633 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3829
      Issue No: Vol. 15, No. 10 (2014)
       
  • Cation-chloride cotransporters in neuronal development, plasticity and
           disease
    • Authors: Kai Kaila, Theodore J. Price, John A. Payne, Martin Puskarjov, Juha Voipio
      Pages: 637 - 654
      Abstract: Electrical activity in neurons requires a seamless functional coupling between plasmalemmal ion channels and ion transporters. Although ion channels have been studied intensively for several decades, research on ion transporters is in its infancy. In recent years, it has become evident that one family of
      Citation: Nature Reviews Neuroscience 15, 637 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3819
      Issue No: Vol. 15, No. 10 (2014)
       
  • Functional organization of the hippocampal longitudinal axis
    • Authors: Bryan A. Strange, Menno P. Witter, Ed S. Lein, Edvard I. Moser
      Pages: 655 - 669
      Abstract: The precise functional role of the hippocampus remains a topic of much debate. The dominant view is that the dorsal (or posterior) hippocampus is implicated in memory and spatial navigation and the ventral (or anterior) hippocampus mediates anxiety-related behaviours. However, this 'dichotomy view' may need
      Citation: Nature Reviews Neuroscience 15, 655 (2014)
      PubDate: 2014-09-19
      DOI: 10.1038/nrn3785
      Issue No: Vol. 15, No. 10 (2014)
       
  • The neuroscience of prejudice and stereotyping
    • Authors: David M. Amodio
      Pages: 670 - 682
      Abstract: Despite global increases in diversity, social prejudices continue to fuel intergroup conflict, disparities and discrimination. Moreover, as norms have become more egalitarian, prejudices seem to have 'gone underground', operating covertly and often unconsciously, such that they are difficult to detect and control. Neuroscientists have recently
      Citation: Nature Reviews Neuroscience 15, 670 (2014)
      PubDate: 2014-09-04
      DOI: 10.1038/nrn3800
      Issue No: Vol. 15, No. 10 (2014)
       
  • Modern network science of neurological disorders
    • Authors: Cornelis J. Stam
      Pages: 683 - 695
      Abstract: Modern network science has revealed fundamental aspects of normal brain-network organization, such as small-world and scale-free patterns, hierarchical modularity, hubs and rich clubs. The next challenge is to use this knowledge to gain a better understanding of brain disease. Recent developments in the application of
      Citation: Nature Reviews Neuroscience 15, 683 (2014)
      PubDate: 2014-09-04
      DOI: 10.1038/nrn3801
      Issue No: Vol. 15, No. 10 (2014)
       
 
 
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