Journal Cover
Nature Reviews Genetics
Journal Prestige (SJR): 34.896
Citation Impact (citeScore): 17
Number of Followers: 311  
  Full-text available via subscription Subscription journal
ISSN (Print) 1471-0056 - ISSN (Online) 1471-0064
Published by NPG Homepage  [138 journals]
  • Genotype–phenotype mapping in another dimension
    • Nature Reviews Genetics, Published online: 19 August 2019; doi:10.1038/s41576-019-0170-y

      A study in Science shows that it is now possible to create high-resolution, non-linear maps of mammalian genetic interactions.Nature Reviews Genetics, Published online: 2019-08-19; doi:10.1038/s41576-019-0170-y2019-08-19
      DOI: 10.1038/s41576-019-0170-y
  • Diversity matters
    • Nature Reviews Genetics, Published online: 16 August 2019; doi:10.1038/s41576-019-0162-y

      For genomics to fulfil its potential of improving human health, diversity and inclusion must be recognized as essential catalysts of research success.Nature Reviews Genetics, Published online: 2019-08-16; doi:10.1038/s41576-019-0162-y2019-08-16
      DOI: 10.1038/s41576-019-0162-y
  • Nascent RNA analyses: tracking transcription and its regulation
    • Nature Reviews Genetics, Published online: 09 August 2019; doi:10.1038/s41576-019-0159-6

      This Review provides an overview of different approaches for measuring nascent RNA synthesis. It discusses the complementary strengths of these different methods and how they have contributed to a mechanistic understanding of transcription regulation.Nature Reviews Genetics, Published online: 2019-08-09; doi:10.1038/s41576-019-0159-62019-08-09
      DOI: 10.1038/s41576-019-0159-6
  • The biogenesis, biology and characterization of circular RNAs
    • Nature Reviews Genetics, Published online: 08 August 2019; doi:10.1038/s41576-019-0158-7

      In eukaryotes, circular RNAs (circRNAs) carry out important biological roles by acting as microRNA or protein sponges, regulating protein function or through cap-independent translation. New technologies for identifying and characterizing circRNAs will increase our knowledge of their biogenesis and function in health and disease.Nature Reviews Genetics, Published online: 2019-08-08; doi:10.1038/s41576-019-0158-72019-08-08
      DOI: 10.1038/s41576-019-0158-7
  • Expanding options for RNA based editors
    • Nature Reviews Genetics, Published online: 06 August 2019; doi:10.1038/s41576-019-0167-6

      Two recent studies report innovative RNA base editing tools: adenine editing without the requirement for exogenous enzymes, and a new ability to edit cytosines.Nature Reviews Genetics, Published online: 2019-08-06; doi:10.1038/s41576-019-0167-62019-08-06
      DOI: 10.1038/s41576-019-0167-6
  • Decoding dragon DNA
    • Nature Reviews Genetics, Published online: 06 August 2019; doi:10.1038/s41576-019-0168-5

      A study in Nature Ecology and Evolution reports the genome sequence of the Komodo dragon and describes genomic features that may underlie its distinct physiology.Nature Reviews Genetics, Published online: 2019-08-06; doi:10.1038/s41576-019-0168-52019-08-06
      DOI: 10.1038/s41576-019-0168-5
  • Toppling TAD tenets
    • Nature Reviews Genetics, Published online: 31 July 2019; doi:10.1038/s41576-019-0164-9

      A study in Nature Genetics shows that genomic rearrangements that cause extensive changes to chromatin topology do not alter expression for the majority of genes.Nature Reviews Genetics, Published online: 2019-07-31; doi:10.1038/s41576-019-0164-92019-07-31
      DOI: 10.1038/s41576-019-0164-9
  • DNA sensing by the cGAS–STING pathway in health and disease
    • Nature Reviews Genetics, Published online: 29 July 2019; doi:10.1038/s41576-019-0151-1

      The cGAS–STING pathway forms a major DNA-sensing mechanism in mammalian cells. This Review summarizes the current knowledge of cGAS–STING signalling and regulation, highlighting emerging evidence of its role in monogenic inflammatory diseases and cancer and new therapeutic opportunities.Nature Reviews Genetics, Published online: 2019-07-29; doi:10.1038/s41576-019-0151-12019-07-29
      DOI: 10.1038/s41576-019-0151-1
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