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Nature Neuroscience
Journal Prestige (SJR): 15.207
Citation Impact (citeScore): 15
Number of Followers: 422  
 
  Full-text available via subscription Subscription journal
ISSN (Print) 1097-6256 - ISSN (Online) 1546-1726
Published by NPG Homepage  [143 journals]
  • Integration of gene expression and brain-wide connectivity reveals the
           multiscale organization of mouse hippocampal networks
    • Integration of gene expression and brain-wide connectivity reveals the multiscale organization of mouse hippocampal networks

      Integration of gene expression and brain-wide connectivity reveals the multiscale organization of mouse hippocampal networks, Published online: 08 October 2018; doi:10.1038/s41593-018-0241-y

      Bienkowski et al. have created a new subregional atlas of the mouse hippocampus that integrates gene expression with anatomical connectivity to reveal the multiscale organization of the hippocampus and its connections throughout the brain.Integration of gene expression and brain-wide connectivity reveals the multiscale organization of mouse hippocampal networks, Published online: 2018-10-08; doi:10.1038/s41593-018-0241-y2018-10-08
      DOI: 10.1038/s41593-018-0241-y
       
  • Maladaptive cortical hyperactivity upon recovery from experimental
           autoimmune encephalomyelitis
    • Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis

      Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis, Published online: 26 September 2018; doi:10.1038/s41593-018-0193-2

      The authors report TNFα-dependent hyperactivity in cortical microcircuits during remission in a mouse model of multiple sclerosis, a maladaptive response to the immune attack with behavioral changes.Maladaptive cortical hyperactivity upon recovery from experimental autoimmune encephalomyelitis, Published online: 2018-09-26; doi:10.1038/s41593-018-0193-22018-09-26
      DOI: 10.1038/s41593-018-0193-2
       
  • Propagation and spread of pathogenic protein assemblies in
           neurodegenerative diseases
    • Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases

      Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases, Published online: 26 September 2018; doi:10.1038/s41593-018-0238-6

      Many neurodegenerative diseases involve the seeded propagation and spread of abnormally shaped proteins within the nervous system. The resulting disease reflects the interaction between the misfolded proteins and the host milieu.Propagation and spread of pathogenic protein assemblies in neurodegenerative diseases, Published online: 2018-09-26; doi:10.1038/s41593-018-0238-62018-09-26
      DOI: 10.1038/s41593-018-0238-6
       
  • Double threat in striatal dopamine signaling
    • Double threat in striatal dopamine signaling

      Double threat in striatal dopamine signaling, Published online: 26 September 2018; doi:10.1038/s41593-018-0243-9

      In this issue of Nature Neuroscience, Menegas et al. demonstrate a role for midbrain dopamine neurons projecting to the tail of the striatum in encoding stimulus novelty and threat avoidance. From this study emerges a model whereby distinct dopaminergic projections to striatum influence behavior along at least two axes, one representing value and one representing threat.Double threat in striatal dopamine signaling, Published online: 2018-09-26; doi:10.1038/s41593-018-0243-92018-09-26
      DOI: 10.1038/s41593-018-0243-9
       
  • Microglia in neurodegeneration
    • Microglia in neurodegeneration

      Microglia in neurodegeneration, Published online: 26 September 2018; doi:10.1038/s41593-018-0242-x

      Microglia are the sentinels, housekeepers, and defenders of the brain. In this review we consider the immune checkpoints that control microglial functions and discuss how their imbalance and subsequent neuroinflammation leads to neurodegeneration.Microglia in neurodegeneration, Published online: 2018-09-26; doi:10.1038/s41593-018-0242-x2018-09-26
      DOI: 10.1038/s41593-018-0242-x
       
  • Triple dissociation of attention and decision computations across
           prefrontal cortex
    • Triple dissociation of attention and decision computations across prefrontal cortex

      Triple dissociation of attention and decision computations across prefrontal cortex, Published online: 26 September 2018; doi:10.1038/s41593-018-0239-5

      Hunt, Malalasekera et al. recorded populations of prefrontal neurons from monkeys performing a visual attention-guided-choice task. The results revealed that distinct computations in three PFC subregions as information was sampled guided the eventual decision.Triple dissociation of attention and decision computations across prefrontal cortex, Published online: 2018-09-26; doi:10.1038/s41593-018-0239-52018-09-26
      DOI: 10.1038/s41593-018-0239-5
       
  • Deconstructing and targeting the genomic architecture of human
           neurodegeneration
    • Deconstructing and targeting the genomic architecture of human neurodegeneration

      Deconstructing and targeting the genomic architecture of human neurodegeneration, Published online: 26 September 2018; doi:10.1038/s41593-018-0240-z

      Older people often have more than one form of neuropathology. The authors describe how insights from the genomic architecture of syndromically defined neurodegenerative diseases can be integrated to inform person-specific trajectories of brain aging.Deconstructing and targeting the genomic architecture of human neurodegeneration, Published online: 2018-09-26; doi:10.1038/s41593-018-0240-z2018-09-26
      DOI: 10.1038/s41593-018-0240-z
       
  • Converging pathways in neurodegeneration, from genetics to mechanisms
    • Converging pathways in neurodegeneration, from genetics to mechanisms

      Converging pathways in neurodegeneration, from genetics to mechanisms, Published online: 26 September 2018; doi:10.1038/s41593-018-0237-7

      Neurodegenerative diseases cause progressive loss of brain functions associated with aging. Here we review intricate genotype–phenotype relationships, shared pathogenic mechanisms, and emerging therapeutic opportunities and challenges.Converging pathways in neurodegeneration, from genetics to mechanisms, Published online: 2018-09-26; doi:10.1038/s41593-018-0237-72018-09-26
      DOI: 10.1038/s41593-018-0237-7
       
 
 
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