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Journal Cover Nature Methods
  [SJR: 21.715]   [H-I: 189]   [321 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1548-7091 - ISSN (Online) 1548-7105
   Published by NPG Homepage  [135 journals]
  • Quantitative mapping and minimization of super-resolution optical imaging
           artifacts
    • Quantitative mapping and minimization of super-resolution optical imaging artifacts

      Quantitative mapping and minimization of super-resolution optical imaging artifacts, Published online: 19 February 2018; doi:10.1038/nmeth.4605

      This paper reports an approach to map errors in super-resolution images, based on quantitative comparison to diffraction-limited equivalents.Quantitative mapping and minimization of super-resolution optical imaging artifacts, Published online: 2018-02-19; doi:10.1038/nmeth.46052018-02-19
      DOI: 10.1038/nmeth.4605
       
  • On the design of CRISPR-based single-cell molecular screens
    • On the design of CRISPR-based single-cell molecular screens

      On the design of CRISPR-based single-cell molecular screens, Published online: 19 February 2018; doi:10.1038/nmeth.4604

      CRISPR-based single-cell pooled screens that use linked barcodes suffer from lost sensitivity due to lentiviral template switching. The barcode-free CROP-seq design circumvents this problem.On the design of CRISPR-based single-cell molecular screens, Published online: 2018-02-19; doi:10.1038/nmeth.46042018-02-19
      DOI: 10.1038/nmeth.4604
       
  • Identifying the favored mutation in a positive selective sweep
    • Identifying the favored mutation in a positive selective sweep

      Identifying the favored mutation in a positive selective sweep, Published online: 19 February 2018; doi:10.1038/nmeth.4606

      The iSAFE software accurately identifies the favored mutation within a positive selective sweep region of the genome.Identifying the favored mutation in a positive selective sweep, Published online: 2018-02-19; doi:10.1038/nmeth.46062018-02-19
      DOI: 10.1038/nmeth.4606
       
  • Capturing the interactome of newly transcribed RNA
    • Capturing the interactome of newly transcribed RNA

      Capturing the interactome of newly transcribed RNA, Published online: 12 February 2018; doi:10.1038/nmeth.4595

      Labeling newly transcribed RNA with 5-ethynyluridine and adding biotin via click chemistry allows the analysis of the proteome bound to the various RNA species, including nascent RNA.Capturing the interactome of newly transcribed RNA, Published online: 2018-02-12; doi:10.1038/nmeth.45952018-02-12
      DOI: 10.1038/nmeth.4595
       
  • RNA–protein interaction detection in living cells
    • RNA–protein interaction detection in living cells

      RNA–protein interaction detection in living cells, Published online: 05 February 2018; doi:10.1038/nmeth.4601

      RaPID uses biotin ligases BirA* and the faster acting BASU to label proteins in the proximity of an RNA motif of interest in living cells.RNA–protein interaction detection in living cells, Published online: 2018-02-05; doi:10.1038/nmeth.46012018-02-05
      DOI: 10.1038/nmeth.4601
       
  • The Author File: Jennifer Phillips-Cremins
    • The Author File: Jennifer Phillips-Cremins

      The Author File: Jennifer Phillips-Cremins, Published online: 30 January 2018; doi:10.1038/nmeth.4584

      To better explore how genomes fold takes disparate fields and a love of math.The Author File: Jennifer Phillips-Cremins, Published online: 2018-01-30; doi:10.1038/nmeth.45842018-01-30
      DOI: 10.1038/nmeth.4584
       
  • Neuroscience: Myelin quantification at nanoscale
    • Neuroscience: Myelin quantification at nanoscale

      Neuroscience: Myelin quantification at nanoscale, Published online: 30 January 2018; doi:10.1038/nmeth.4586

      Neuroscience: Myelin quantification at nanoscaleNeuroscience: Myelin quantification at nanoscale, Published online: 2018-01-30; doi:10.1038/nmeth.45862018-01-30
      DOI: 10.1038/nmeth.4586
       
  • Imaging: A colorful series of bioorthogonal probes
    • Imaging: A colorful series of bioorthogonal probes

      Imaging: A colorful series of bioorthogonal probes, Published online: 30 January 2018; doi:10.1038/nmeth.4590

      Imaging: A colorful series of bioorthogonal probesImaging: A colorful series of bioorthogonal probes, Published online: 2018-01-30; doi:10.1038/nmeth.45902018-01-30
      DOI: 10.1038/nmeth.4590
       
 
 
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