for Journals by Title or ISSN
for Articles by Keywords
help
Followed Journals
Journal you Follow: 0
 
Sign Up to follow journals, search in your chosen journals and, optionally, receive Email Alerts when new issues of your Followed Journals are published.
Already have an account? Sign In to see the journals you follow.
Journal Cover Nature Medicine
  [SJR: 13.959]   [H-I: 439]   [747 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1078-8956 - ISSN (Online) 1546-170X
   Published by NPG Homepage  [143 journals]
  • Resetting the epigenetic balance of Polycomb and COMPASS function at
           enhancers for cancer therapy
    • Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy

      Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy, Published online: 21 May 2018; doi:10.1038/s41591-018-0034-6

      Interactions between the MLL3 histone methyltransferase and the BAP1–UTX complex set the level of histone H3K27 methylation and suggest a new therapy for MLL3-mutant cancer.Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy, Published online: 2018-05-21; doi:10.1038/s41591-018-0034-62018-05-21
      DOI: 10.1038/s41591-018-0034-6
       
  • Targeting G-quadruplex DNA as cognitive function therapy for ATR-X
           syndrome
    • Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome

      Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome, Published online: 21 May 2018; doi:10.1038/s41591-018-0018-6

      In a mouse model of intellectual disability, the chromatin remodeling protein ATR-X is shown to bind to G-quadruplex DNA structures and modulate target gene expression, which can be pharmacologically targeted to restore neuronal and cognitive phenotypes in these animals.Targeting G-quadruplex DNA as cognitive function therapy for ATR-X syndrome, Published online: 2018-05-21; doi:10.1038/s41591-018-0018-62018-05-21
      DOI: 10.1038/s41591-018-0018-6
       
  • HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+
           monocytes is associated with a decreased risk of SIVmac251 acquisition
    • HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition

      HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition, Published online: 21 May 2018; doi:10.1038/s41591-018-0025-7

      Distinct monocyte subsets associate with different outcomes of SIV vaccines.HIV vaccine candidate activation of hypoxia and the inflammasome in CD14+ monocytes is associated with a decreased risk of SIVmac251 acquisition, Published online: 2018-05-21; doi:10.1038/s41591-018-0025-72018-05-21
      DOI: 10.1038/s41591-018-0025-7
       
  • An immune-beige adipocyte communication via nicotinic acetylcholine
           receptor signaling
    • An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling

      An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling, Published online: 21 May 2018; doi:10.1038/s41591-018-0032-8

      Inhibition of immune cell–derived acetylcholine synthesis or of its signaling via CHRNA2 in beige adipocytes reduces thermogenesis and exacerbates diet-induced obesity, suggesting a new mode of immuno–fat communication in energy metabolism.An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling, Published online: 2018-05-21; doi:10.1038/s41591-018-0032-82018-05-21
      DOI: 10.1038/s41591-018-0032-8
       
  • The reference epigenome and regulatory chromatin landscape of chronic
           lymphocytic leukemia
    • The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia

      The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia, Published online: 21 May 2018; doi:10.1038/s41591-018-0028-4

      An integrated resource of (epi)genomic features in annotated chronic lymphocytic leukemia (CLL) primary samples uncovers subgroup-specific regulatory alterations associated with clinical behavior.The reference epigenome and regulatory chromatin landscape of chronic lymphocytic leukemia, Published online: 2018-05-21; doi:10.1038/s41591-018-0028-42018-05-21
      DOI: 10.1038/s41591-018-0028-4
       
  • Targeting skeletal endothelium to ameliorate bone loss
    • Targeting skeletal endothelium to ameliorate bone loss

      Targeting skeletal endothelium to ameliorate bone loss, Published online: 21 May 2018; doi:10.1038/s41591-018-0020-z

      Recombinant SLIT3 represents a new mechanistic approach to treating osteoporosis by increasing skeletal CD31hiEMCNhi vascular endothelium.Targeting skeletal endothelium to ameliorate bone loss, Published online: 2018-05-21; doi:10.1038/s41591-018-0020-z2018-05-21
      DOI: 10.1038/s41591-018-0020-z
       
  • Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces
           polycystic ovary syndrome in adulthood
    • Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood

      Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood, Published online: 14 May 2018; doi:10.1038/s41591-018-0035-5

      Excess anti-Müllerian hormone during pregnancy results in polycystic ovary syndrome-like phenotypes in female offspring, possibly explaining its pathogenesis as well as suggesting a possible therapy.Elevated prenatal anti-Müllerian hormone reprograms the fetus and induces polycystic ovary syndrome in adulthood, Published online: 2018-05-14; doi:10.1038/s41591-018-0035-52018-05-14
      DOI: 10.1038/s41591-018-0035-5
       
  • CAR T cells for childhood diffuse midline gliomas
    • CAR T cells for childhood diffuse midline gliomas

      CAR T cells for childhood diffuse midline gliomas, Published online: 07 May 2018; doi:10.1038/s41591-018-0031-9

      Anti-GD2 chimeric antigen receptor (CAR)-modified T cells may be a new and innovative approach for the treatment of pediatric H3-K27M-mutant diffuse midline gliomas.CAR T cells for childhood diffuse midline gliomas, Published online: 2018-05-07; doi:10.1038/s41591-018-0031-92018-05-07
      DOI: 10.1038/s41591-018-0031-9
       
 
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
 
Home (Search)
Subjects A-Z
Publishers A-Z
Customise
APIs
Your IP address: 54.81.78.135
 
About JournalTOCs
API
Help
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-