for Journals by Title or ISSN
for Articles by Keywords
help
Followed Journals
Journal you Follow: 0
 
Sign Up to follow journals, search in your chosen journals and, optionally, receive Email Alerts when new issues of your Followed Journals are published.
Already have an account? Sign In to see the journals you follow.
Journal Cover Nature Medicine
  [SJR: 13.959]   [H-I: 439]   [699 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 1078-8956 - ISSN (Online) 1546-170X
   Published by NPG Homepage  [134 journals]
  • Granulocyte-derived TNFα promotes vascular and hematopoietic
           regeneration in the bone marrow
    • Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow

      Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow, Published online: 20 November 2017; doi:10.1038/nm.4448

      In the bone marrow, granulocyte-derived TNFα acts on endothelial cells to maintain the vasculature under steady-state conditions and to promote its regeneration after injury or transplantation.Granulocyte-derived TNFα promotes vascular and hematopoietic regeneration in the bone marrow, Published online: 2017-11-20; doi:10.1038/nm.44482017-11-20
      DOI: 10.1038/nm.4448
       
  • CD22-targeted CAR T cells induce remission in B-ALL that is naive or
           resistant to CD19-targeted CAR immunotherapy
    • CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy

      CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy, Published online: 20 November 2017; doi:10.1038/nm.4441

      Fry et al. report the first results from a human trial of a CD22-directed chimeric antigen receptor (CAR) T cell therapy providing evidence of efficacy in the treatment of pre–B cell acute lymphoblastic leukemia that is immunotherapy-naive or resistant to CD19-directed CAR T cells.CD22-targeted CAR T cells induce remission in B-ALL that is naive or resistant to CD19-targeted CAR immunotherapy, Published online: 2017-11-20; doi:10.1038/nm.44412017-11-20
      DOI: 10.1038/nm.4441
       
  • Human primary liver cancer–derived organoid cultures for disease
           modeling and drug screening
    • Human primary liver cancer–derived organoid cultures for disease modeling and drug screening

      Human primary liver cancer–derived organoid cultures for disease modeling and drug screening, Published online: 13 November 2017; doi:10.1038/nm.4438

      NatureArticleSnippet(type=short-summary, markup=

      Tumor organoids derived from the most common subtypes of primary liver cancer recapitulate the histologic and molecular features of the tissues of origin, even after long-term culture. These in vitro models, as well as those for colorectal cancer reported in Crespo et al. in a previous issue, are amenable for drug screening and allow the identification of therapeutic approaches with potential for cancer treatment.

      , isJats=true)Human primary liver cancer–derived organoid cultures for disease modeling and drug screening, Published online: 2017-11-13; doi:10.1038/nm.44382017-11-13
      DOI: 10.1038/nm.4438
       
  • Targeting the T cell receptor β-chain constant region for
           immunotherapy of T cell malignancies
    • Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies

      Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies, Published online: 13 November 2017; doi:10.1038/nm.4444

      NatureArticleSnippet(type=short-summary, markup=

      Pule and colleagues identify the TCR β-chain constant region as a new target for chimeric antigen receptor (CAR) T cells in treatment of T cell cancers while potentially preserving a healthy T cell repertoire. They demonstrate that anti-TCRB1 CAR T cells eliminate cancerous TCRB1+ T cells while sparing nearly one-third of normal TCRB2+ T cells.

      , isJats=true)Targeting the T cell receptor β-chain constant region for immunotherapy of T cell malignancies, Published online: 2017-11-13; doi:10.1038/nm.44442017-11-13
      DOI: 10.1038/nm.4444
       
  • UCP1-independent signaling involving SERCA2b-mediated calcium cycling
           regulates beige fat thermogenesis and systemic glucose homeostasis
    • UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis

      UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis, Published online: 13 November 2017; doi:10.1038/nm.4429

      NatureArticleSnippet(type=short-summary, markup=

      Calcium cycling induced by the SERCA2b–RyR2 pathway in beige fat cells allows for thermogenic activity independent of UCP1.

      , isJats=true)UCP1-independent signaling involving SERCA2b-mediated calcium cycling regulates beige fat thermogenesis and systemic glucose homeostasis, Published online: 2017-11-13; doi:10.1038/nm.44292017-11-13
      DOI: 10.1038/nm.4429
       
  • Enhancing the precision of genetic lineage tracing using dual recombinases
    • Enhancing the precision of genetic lineage tracing using dual recombinases

      Enhancing the precision of genetic lineage tracing using dual recombinases, Published online: 13 November 2017; doi:10.1038/nm.4437

      NatureArticleSnippet(type=short-summary, markup=

      Genetic cell-lineage tracing studies in mice are crucial for delineating the contribution of stem and progenitor cells to different cell types, both in disease states and after regenerative therapy. He et al. have developed new genetic lineage-tracing systems that provide more definitive results than the commonly used Cre-based system and show that this new technology can resolve current controversies in the field, as demonstrated by lineage-tracing studies in the heart and liver.

      , isJats=true)Enhancing the precision of genetic lineage tracing using dual recombinases, Published online: 2017-11-13; doi:10.1038/nm.44372017-11-13
      DOI: 10.1038/nm.4437
       
  • Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced
           type-2 allergic asthma exacerbation
    • Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation

      Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation, Published online: 07 November 2017; doi:10.1038/nm1117-1384a

      Corrigendum: Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation, Published online: 2017-11-07; doi:10.1038/nm1117-1384a2017-11-07
      DOI: 10.1038/nm1117-1384a
       
  • Corrigendum: Targeting cellular senescence prevents age-related bone loss
           in mice
    • Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice

      Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice, Published online: 07 November 2017; doi:10.1038/nm1117-1384c

      Corrigendum: Targeting cellular senescence prevents age-related bone loss in mice, Published online: 2017-11-07; doi:10.1038/nm1117-1384c2017-11-07
      DOI: 10.1038/nm1117-1384c
       
 
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
 
Home (Search)
Subjects A-Z
Publishers A-Z
Customise
APIs
Your IP address: 23.20.129.162
 
About JournalTOCs
API
Help
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-2016