Subjects -> HEALTH AND SAFETY (Total: 1541 journals)
    - CIVIL DEFENSE (22 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (722 journals)
    - WOMEN'S HEALTH (82 journals)

PHYSICAL FITNESS AND HYGIENE (130 journals)                     

Showing 1 - 130 of 130 Journals sorted alphabetically
ACSMs Health & Fitness Journal     Full-text available via subscription   (Followers: 15)
Acta Facultatis Educationis Physicae Universitatis Comenianae     Open Access   (Followers: 4)
Acta Kinesiologiae Universitatis Tartuensis     Open Access   (Followers: 1)
ACTIVE : Journal of Physical Education, Sport, Health and Recreation     Open Access   (Followers: 31)
Adapted Physical Activity Quarterly     Hybrid Journal   (Followers: 5)
African Journal for Physical, Health Education, Recreation and Dance     Full-text available via subscription   (Followers: 7)
Ágora para la Educación Física y el Deporte     Open Access  
Al.Qadisiya journal for the Sciences of Physical Education     Open Access  
American Journal of Sexuality Education     Hybrid Journal   (Followers: 4)
Annals of Applied Sport Science     Open Access   (Followers: 11)
Annals of Work Exposures and Health     Hybrid Journal   (Followers: 11)
Applied Physiology, Nutrition and Metabolism     Hybrid Journal   (Followers: 34)
Apunts. Medicina de l'Esport     Full-text available via subscription   (Followers: 1)
Arab Journal of Nutrition and Exercise     Open Access   (Followers: 1)
Archives of Exercise in Health and Disease     Open Access   (Followers: 7)
Arquivos de Ciências do Esporte     Open Access  
Arquivos em Movimento     Open Access   (Followers: 1)
Arrancada     Open Access   (Followers: 1)
Athletic Training & Sports Health Care     Full-text available via subscription   (Followers: 24)
BMC Obesity     Open Access   (Followers: 8)
BMC Sports Science, Medicine and Rehabilitation     Open Access   (Followers: 35)
Childhood Obesity     Hybrid Journal   (Followers: 24)
Clinical Journal of Sport Medicine     Hybrid Journal   (Followers: 36)
Comparative Exercise Physiology     Hybrid Journal   (Followers: 25)
Cultura, Ciencia y Deporte     Open Access   (Followers: 2)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 24)
eJRIEPS : Ejournal de la recherche sur l'intervention en éducation physique et sport     Open Access  
Environmental Health and Preventive Medicine     Open Access   (Followers: 4)
Éthique & Santé     Full-text available via subscription  
Fat Studies : An Interdisciplinary Journal of Body Weight and Society     Partially Free   (Followers: 3)
Fisioterapia em Movimento     Open Access  
Fitness & Performance Journal     Open Access   (Followers: 3)
Food Science and Human Wellness     Open Access   (Followers: 5)
Frontiers in Sports and Active Living     Open Access   (Followers: 2)
Gelanggang Pendidikan Jasmani Indonesia     Open Access  
German Journal of Exercise and Sport Research : Sportwissenschaft     Hybrid Journal   (Followers: 4)
Geron     Full-text available via subscription  
Global Journal of Health and Physical Education Pedagogy     Full-text available via subscription   (Followers: 2)
Health and Quality of Life Outcomes     Open Access   (Followers: 15)
Health Education Journal     Hybrid Journal   (Followers: 17)
Health Marketing Quarterly     Hybrid Journal   (Followers: 3)
Health Physics     Hybrid Journal   (Followers: 7)
Home Healthcare Now     Hybrid Journal   (Followers: 5)
Human Movement     Open Access   (Followers: 14)
Human Movement Science     Hybrid Journal   (Followers: 17)
IISE Transactions on Occupational Ergonomics and Human Factors     Hybrid Journal  
Indonesia Performance Journal     Open Access  
İnönü Üniversitesi Beden Eğitimi ve Spor Bilimleri Dergisi     Open Access  
International Journal for Vitamin and Nutrition Research     Hybrid Journal   (Followers: 12)
International Journal of Applied Exercise Physiology     Open Access   (Followers: 60)
International Journal of Athletic Therapy & Training     Hybrid Journal   (Followers: 15)
International Journal of Behavioral Nutrition and Physical Activity     Open Access   (Followers: 30)
International Journal of Men's Health     Full-text available via subscription   (Followers: 5)
International Journal of Obesity     Hybrid Journal   (Followers: 94)
International Journal of Obesity Supplements     Full-text available via subscription   (Followers: 8)
International Journal of Qualitative Studies on Health and Well-Being     Open Access   (Followers: 21)
International Journal of Spa and Wellness     Hybrid Journal  
International Journal of Sport, Exercise & Training Sciences     Open Access   (Followers: 2)
International Journal of Yoga     Open Access   (Followers: 17)
Isokinetics and Exercise Science     Hybrid Journal   (Followers: 12)
Journal of American College Health     Hybrid Journal   (Followers: 4)
Journal of Athlete Development and Experience     Open Access   (Followers: 1)
Journal of Bioenergetics and Biomembranes     Hybrid Journal   (Followers: 1)
Journal of Human Performance in Extreme Environments     Open Access   (Followers: 2)
Journal of Human Sport and Exercise     Open Access   (Followers: 19)
Journal of Motor Learning and Development     Hybrid Journal  
Journal of Physical Activity and Health     Hybrid Journal   (Followers: 11)
Journal of Physical Activity and Hormones     Open Access   (Followers: 1)
Journal of Physical Activity Research     Open Access   (Followers: 5)
Journal of Physical Education and Human Movement     Open Access  
Journal of Physical Education and Sport Sciences     Open Access   (Followers: 2)
Journal of Physical Education Health and Sport     Open Access   (Followers: 2)
Journal of Physical Education, Recreation & Dance     Full-text available via subscription   (Followers: 15)
Journal of Science in Sport and Exercise     Hybrid Journal   (Followers: 5)
Journal of Sport and Health Science     Open Access   (Followers: 23)
Journal of Sport Sciences and Fitness     Open Access   (Followers: 16)
Journal of Strength and Conditioning Research     Hybrid Journal   (Followers: 78)
Journal of Yoga & Physical Therapy     Open Access   (Followers: 9)
Jurnal Pendidikan Kesehatan Rekreasi     Open Access   (Followers: 4)
Kerbala Magazine of Physical Edu. Seiences     Open Access   (Followers: 2)
Kinesiology : International Journal of Fundamental and Applied Kinesiology     Open Access  
Kinesiology Review     Hybrid Journal   (Followers: 6)
Krankenhaus-Hygiene - Infektionsverhütung     Full-text available via subscription  
Measurement in Physical Education and Exercise Science     Hybrid Journal   (Followers: 7)
Médecine & Nutrition     Full-text available via subscription  
Mental Health and Physical Activity     Hybrid Journal   (Followers: 17)
MHSalud : Movimiento Humano y Salud     Open Access  
Obesity     Hybrid Journal   (Followers: 58)
Obesity Research & Clinical Practice     Full-text available via subscription   (Followers: 21)
Obesity Reviews     Hybrid Journal   (Followers: 26)
Obesity Science & Practice     Open Access   (Followers: 1)
Open Obesity Journal     Open Access   (Followers: 1)
Pain Management in General Practice     Full-text available via subscription   (Followers: 12)
PALAESTRA : Adapted Sport, Physical Education, and Recreational Therapy     Full-text available via subscription   (Followers: 4)
Physical Activity and Health     Open Access   (Followers: 3)
Physical Education & Sport Pedagogy     Hybrid Journal   (Followers: 12)
Preventing Chronic Disease     Free   (Followers: 2)
Psychology of Sport and Exercise     Hybrid Journal   (Followers: 21)
Quality in Sport     Open Access   (Followers: 1)
Race and Yoga     Open Access   (Followers: 5)
RBNE - Revista Brasileira de Nutrição Esportiva     Open Access   (Followers: 1)
RBONE - Revista Brasileira de Obesidade, Nutrição e Emagrecimento     Open Access  
RBPFEX - Revista Brasileira de Prescrição e Fisiologia do Exercício     Open Access  
Research Quarterly for Exercise and Sport     Hybrid Journal   (Followers: 1)
Retos : Nuevas Tendencias en Educación Física, Deportes y Recreación     Open Access  
Revista Andaluza de Medicina del Deporte     Open Access   (Followers: 2)
Revista Brasileira de Atividade Física & Saúde     Open Access  
Revista Brasileira de Ciências do Esporte     Open Access   (Followers: 1)
Revista Brasileira de Cineantropometria & Desempenho Humano     Open Access   (Followers: 1)
Revista Brasileira de Educação Física e Esporte     Open Access   (Followers: 2)
Revista da Educação Física : UEM     Open Access   (Followers: 1)
Revista Iberoamericana de Psicología del Ejercicio y el Deporte     Open Access  
Revista Internacional de Medicina y Ciencias de la Actividad Física y del Deporte : International Journal of Medicine and Science of Physical Activity and Sport     Open Access   (Followers: 1)
Revue phénEPS / PHEnex Journal     Open Access  
Scandinavian Journal of Sport and Exercise Psychology     Open Access   (Followers: 8)
SIPATAHOENAN : South-East Asian Journal for Youth, Sports & Health Education     Open Access  
Spor Bilimleri Dergisi / Hacettepe Journal of Sport Sciences     Open Access  
Sport and Fitness Journal     Open Access   (Followers: 5)
Sport Health     Full-text available via subscription   (Followers: 3)
Sport Sciences for Health     Hybrid Journal   (Followers: 5)
Sport- und Präventivmedizin     Hybrid Journal   (Followers: 3)
SPORTIVE : Journal Of Physical Education, Sport and Recreation     Open Access   (Followers: 5)
Sports     Open Access   (Followers: 2)
Sports Biomechanics     Hybrid Journal   (Followers: 29)
Sports Health: A Multidisciplinary Approach     Hybrid Journal   (Followers: 4)
Strength & Conditioning Journal     Hybrid Journal   (Followers: 65)
Timisoara Physical Education and Rehabilitation Journal     Open Access   (Followers: 4)
Turkish Journal of Sport and Exercise     Open Access  
Yoga Mimamsa     Open Access   (Followers: 2)
Здоровье человека, теория и методика физической культуры и спорта     Open Access  


Similar Journals
Journal Cover
Food Science and Human Wellness
Number of Followers: 5  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2213-4530
Published by Ke Ai Homepage  [68 journals]
  • Research Progress of Gut Flora in Improving Human Wellness

    • Abstract: Publication date: Available online 21 March 2019Source: Food Science and Human WellnessAuthor(s): Chenggang Zhang, Wenjing Gong, Zhihui Li, Dawen Gao, Yan Gao Human wellness is the ultimate goal of our efforts in improving the human life. Special foods are undoubtedly important in achieving human wellness. However, overeating significantly leads to obesity and diabetes. These chronic diseases will in turn affect the human wellness. Therefore, “dietary restriction and proper exercise” were introduced in the human daily life. Different foods cause various effects on the human health. The diversification of diet is a priority for nutritionists to keep our body healthy. To avoid diabetes mellitus, special foods for ketogenic diet, low-carbon diet, and low-calorie intake are also gradually attracting attention. In addition, the hypothesis that “hunger sensation comes from gut flora” brings new light to the research on the biological motivation for humans to eat food. This hypothesis has been gradually demonstrated using the flexible fasting technology by providing special foods, such as plant polysaccharides and dietary fibers. The response to food-needing signals from the gut flora to these foods demonstrates the importance of the gut flora in improving human wellness. The gut flora is probably an essential factor for translating the food-eating signals and converting the nutrition to our body. Therefore, “gut flora priority principle” is developed to guarantee human wellness. The 16S rRNA sequencing and mass spectrometric techniques can be used to identify the gut flora, which may guide us to a new era of human wellness based on gut flora wellness.
  • Autophagy-associated signal pathways of functional foods for chronic

    • Abstract: Publication date: Available online 14 March 2019Source: Food Science and Human WellnessAuthor(s): Jinfeng Xie, Jiling Liang, Ning Chen Functional foods, namely as natural or processed foods containing bioactive compounds, can provide health-promoting effects beyond basic nutrition, or offer the prevention or supplementary treatment of chronic diseases. The bioactive components in functional foods usually have pleiotropic effects, including antioxidant, anti-inflammatory, hypolipidemic, glycemic-regulating, cytoprotective, and neuroprotective functions. Autophagy is one of the highly conserved cellular processes for the clearance of aberrant components in eukaryotic cells, and plays an essential role in health promotion and prevention and treatment of a series of chronic diseases. Once the cells are in the stress environment, the induced autophagy will accelerate the clearance of cellular damaged or toxic protein aggregates or dysfunctional cellular organelles to maintain homeostasis in cells. In this article, we summarize several widely investigated bioactive components used as functional foods, such as resveratrol, epigallocatechin-3-gallate, curcumin and trehalose, with the regulatory function for autophagy during the intervention of chronic diseases, which will provide the references or novel thoughts for the development of functional foods with the modulation of autophagy.
  • Comparative analysis of antioxidant activities of essential oils and
           extracts of fennel (Foeniculum vulgare Mill.) seeds from Egypt and China

    • Abstract: Publication date: Available online 14 March 2019Source: Food Science and Human WellnessAuthor(s): Adel F. Ahmed, Mengjin Shi, Cunyu Liu, Wenyi Kang The present study was conducted to assay the antioxidant activities of essential oils and ethanol extracts of fennel (Foeniculum vulgare Mill.) seeds from Egypt and China. The major components of the Egyptian fennel essential oil were estragole (51.04%), limonene (11.45%), l-fenchone (8.19%) and trans-anethole (3.62%) by GC–MS analysis. Whereas, the major constituents of Chinese fennel essential oil were trans-anethole (54.26%), estragole (20.25%), l-fenchone (7.36%) and limonene (2.41%). The fennel seed extracts from Egypt and China contained appreciable levels of total phenolic contents (42.24 and 30.94 mg PE/g, respectively). The extracts exhibited good DPPH radical scavenging capacity with IC50 (6.34 and 7.17 mg/g), respectively. A high variation in free radical scavenging activities of essential oils was observed. The Chinese fennel essential oil showed high activity in DPPH radical scavenging with IC50 (15.66 mg/g). The Egyptian fennel essential oil showed very low activity with IC50 (141.82 mg/g). The results of the present investigation demonstrated significant variations in the antioxidant activities of fennel essential oils and extracts from Egypt and China.
  • Microalgae: A potential alternative to health supplementation for humans

    • Abstract: Publication date: Available online 2 March 2019Source: Food Science and Human WellnessAuthor(s): Apurav Krishna Koyande, Kit Wayne Chew, Krishnamoorthy Rambabu, Yang Tao, Dinh-Toi Chu, Pau-Loke Show Microalgae has been consumed in human diet for thousands of years. It is an under-exploited crop for production of dietary foods. Microalgae cultivation does not compete with land and resources required for traditional crops and has a superior yield compared to terrestrial crops. Its high protein content has exhibited a huge potential to meet the dietary requirements of growing population. Apart from being a source of protein, presence of various bio-active components in microalgae provide an added health benefit. This review describes various microalgal sources of proteins and other bio-active components. One of the heavily studied group of bio-active components are pigments due to their anticarcenogenic, antioxidative and antihypertensive properties. Compared to various plant and floral species, microalgae contain higher amounts of pigments. Microalgal derived proteins have complete Essential Amino Acids (EAA) profiles and their protein content is higher than conventional sources such as meat, poultry and dairy products. However, microalgal based functional foods have not flooded the market. The lack of awareness coupled with scarce incentives for producers result in under-exploitation of microalgal potential. Application of microalgal derived components as dietary and nutraceutical supplements is discussed comprehensively.
  • Medical foods in Alzheimer’s disease

    • Abstract: Publication date: Available online 22 February 2019Source: Food Science and Human WellnessAuthor(s): Klaus W. Lange, Jianjun Guo, Shigehiko Kanaya, Katharina M. Lange, Yukiko Nakamura, Shiming Li Alzheimer’s disease (AD) is the most prevalent cause of dementia worldwide. Treatments achieving a marked improvement in symptoms or preventing or delaying the progression of the disease are not available. Various diet-related risk factors for AD have been identified. Evidence for a protective effect of the Mediterranean diet on AD risk is inconclusive. Medical foods are designed to meet specific dietary needs for certain diseases. Improvements in symptomatology and regional brain atrophy in AD have been claimed for several medical foods, for example, those providing ketone bodies as alternative energy supply to neurons, those containing precursors believed to improve synaptic function, and those addressing oxidative stress related to memory loss. Many methodological shortcomings render the interpretation of the available findings of medical food trials in AD difficult. Optimal results of medical foods in AD may be expected when administered in presymptomatic or early stages of the disease. This requires the reliable identification of minimal neuropathological changes related to AD. The outcome measures currently used may not be able to detect subtle changes in cognition and function in early AD. Large-scale clinical studies using valid, sensitive, and reliable assessment tools are needed to establish the efficacy of medical foods in AD.
  • QSAR modeling of benzoquinone derivatives as 5-lipoxygenase inhibitors

    • Abstract: Publication date: Available online 22 February 2019Source: Food Science and Human WellnessAuthor(s): T.K. Shameera Ahamed, Vijisha K. Rajan, K. Muraleedharan The inhibitors of 5-LOX control the overproduction of pro-inflammatory mediators known as leukotrienes (LTs) and thus have therapeutic relevance in the treatment of various diseases like asthma, rheumatoid arthritis, inflammatory bowel disease and certain types of cancers. This has increased the search for efficient therapeutic agents for protein 5-LOX and this process is now primarily based on QSAR. In this study, we have developed four different quantitative structure and 5-LOX inhibition activity relationship models of benzoquinone derivative by exploiting CoMFA, RF, SVM, and MLR chemometric methods. Performance of the QSAR models was measured by using cross-validation technique as well as through the external test set prediction. RF model outperforms all other models. SVM and MLR models failed due to the poor performance of the external test set prediction. CoMFA model, which shows relatively good performance was used to explore the essential structural regions where the modification was necessary to design a novel scaffold with improved activity. Moreover, molecular docking of all the derivatives to the binding site of 5-LOX was done to show their binding mode and to identify critical interacting residues inside the active site of 5-LOX. The docking result confirms the stability and rationality of the CoMFA model.Graphical abstractGraphical abstract for this article
  • High uric acid model in Caenorhabditis elegans

    • Abstract: Publication date: Available online 19 February 2019Source: Food Science and Human WellnessAuthor(s): Zhenjing Li, Yibin Xue, Nifei Wang, Jingli Cheng, Xiaoying Dong, Qingbin Guo, Changlu Wang To establish experimental high uric acid model in C. elegans. Hypoxanthine, adenine, xanthine, and uric acid were used to treat C. elegans and then hyperuricemic C. elegans was evaluated by allopurinol. Hyperuricemic C. elegans were obtained after normal worms were treated by xanthine (0.25 mg/mL, 18 h). For hyperuricemic worms, there was a statistically significant increase in the uric acid level (p  0.05). Moreover, the model was proved to keep a high uric acid level for up to 12 h. After given allopurinol (0.25 mg/mL, 12 h), the uric acid of hyperuricemic C. elegans had a significant reduction by 15%. Furthermore, xanthine oxidase activity in hyperuricemic C. elegans showed a statistically significant increase (p 
  • Optimization of process conditions for drying of catfish (Clarias
           gariepinus) using Response Surface Methodology (RSM)

    • Abstract: Publication date: Available online 2 February 2019Source: Food Science and Human WellnessAuthor(s): Elijah George Ikrang, Kingsley Charles Umani Drying is applied to lower the moisture content of fish to a level that can prevent the growth of mould and infestation of micro-organism and thus minimizes microbial degradation. The goal of this work was to optimize the process conditions during electrical oven drying of catfish. Moisture content (MC) was quantitatively investigated during the drying process of catfish sizes using response surface methodology (RSM) to obtain minimum moisture content. The independent process variables for the drying process were temperature (50–70 °C), product thickness (10–20 mm), salt concentration (0–20%) and drying time (480–600 min.). Two factorial interaction (2FI) regression model describing the effects of independent drying process variables on the moisture content was developed. The effects of temperature and drying time were more pronounced for MC than the thickness and salt concentration.The optimum conditions were found to be temperature = 63.43 °C, product thickness = 14.81 mm, salt concentration = 9.07% and drying time = 600 min. At these optimum conditions, moisture content was found to be 2.64% w.b. Validation of experimental results with the empirical model was evaluated using coefficient of correlation (R2) which was found for the model equation as, R2 = 0.994.
  • Screening of potential GCMS derived antimigraine compound from the leaves
           of Abrus precatorius Linn to target “calcitonin gene related peptide”
           receptor using in silico analysis

    • Abstract: Publication date: Available online 18 January 2019Source: Food Science and Human WellnessAuthor(s): Parthasarathy V., Ajay Kumar T.V Calcitonin receptor-like receptor (CRLR) is a human protein, that produces a calcitonin gene-related peptide receptor (CGRP) when associates with human receptor activity-modifying protein-1 (HRAMP1). CGRP is believed to be involved in triggering of migraine. Many strategies were employed to design antimigraine drug using various CGRP antagonist/ligands but most of them have failed due to their inability to reach the target “CGRP receptor” as they get metabolized before conferring their pharmacological action and exhibit toxic effect to the liver. The present study, evaluated the binding of 13 phyto-chemical compounds of “Abrus precatorius” identified through GCMS analysis against the protein CGRP using “Discovery Studio software”. The molecular docking study and ADME/T properties prediction were performed with the compounds using C-DOCKER module. The results showed that five lead compounds of A. precatorius may act as good inhibitors for migraine headache and the compounds can be re-designed and synthesized for better antimigraine activity.Graphical abstractGraphical abstract for this article
  • Oral microbiota: A new view of body health

    • Abstract: Publication date: Available online 3 January 2019Source: Food Science and Human WellnessAuthor(s): Maoyang Lu, Songyu Xuan, Zhao Wang Oral microbiota is an important part of the human microbiota. Oral microbes can be colonized into the intestine in various ways. Oral microbiota is associated with a variety of oral diseases. Recently, increasing evidence has shown that the oral microbiota is closely related to the physical state of humans, such as diabetes, obesity, and cancer. In the future, oral microbiota will become a new target for improving the physical state of humans.
  • In vitro antioxidant capacity and free radical scavenging evaluation of
           standardized extract of Costus afer leaf

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): T.G. Atere, O.A. Akinloye, R.N. Ugbaja, D.A. Ojo, G. Dealtry Absolute methanol extract leaf of Costus afer was comprehensively investigated for free radical scavenging activities and antioxidant activities using battery of testing: 1, 1-diphenyl-2-picrylhydrazyl (DPPH) scavenging, hydroxyl radical scavenging, hydrogen peroxide radical scavenging, 2, 2′-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) (ABTS) scavenging, nitric oxide inhibition, anti-lipid peroxidation, ferrous chelating potential, reducing power potential, total antioxidant capacity, cupric reducing antioxidant capacity CUPRAC and ferric reducing antioxidant power (FRAP). The content of phenol, flavonoid, cupric, anthocyanin were also investigated. The results suggest that the antioxidant potentials of the extract may be responsible for its medicinal potentials. Cell viability assay revealed that up to12 μg/ml of the extract is safe for Chang liver cell and no sign of toxicity was observed after the extract treatment of 2000 mg/kg in albino rats.
  • Anti-inflammatory activity of Alpinia officinarum hance on rat colon
           inflammation and tissue damage in DSS induced acute and chronic colitis

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): Vijayabharathi Rajendiran, Vidhya Natarajan, Sivasithamparam Niranjali Devaraj The purpose of this study was to investigate the possible prophylactic effects of Alpinia officinarum hance on experimentally induced acute and chronic colitis models, in-vivo and in-vitro. Acute and chronic colitis were induced in Male Wistar rats by administration of Dextran Sulfate Sodium (DSS) in drinking water. DSS induction exhibited colon shrinkage, increased the Disease Activity Index (DAI) score, increased the levels of inflammatory markers and caused severe anemia. DSS induced animals, co-treated with the hexane extract of Alpinia officinarum (HEAO) (200 mg/kg body wt), effectively suppressed colonic injury that was evidenced by the reduced DAI score, colon weight/length ratio, histological damage, proinflammatory markers and MPO activity. Further, it restored the colonic antioxidants near to normal levels by regulating the oxidative stress via attenuation of lipid peroxidation. Our results revealed that the degree of colitis caused by the administration of DSS was significantly attenuated by HEAO. In addition, the in-vitro study showed that HEAO treatment inhibited the proliferation of HT-29 cells and down regulated the mRNA expression of NF-κB and COX-2. Taken together, these results suggest that HEAO is a promising anti-oxidant and anti-inflammatory agent that support its possible therapeutic role in the treatment of colitis.
  • Application of in vitro and in vivo models in the study
           of food allergy

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): Jianjian Huang, Changjun Liu, Yanbo Wang, Chong Wang, Menghua Xie, Yi Qian, Linglin Fu Food allergy is one of the most important food safety problems that has attracted increasing attention. The food allergy experimental models provide not only the accurate allergen detection and evaluation methods but also the powerful approaches for mechanism investigations. In this paper, we reviewed the common food allergy cell models including mast cell, basophil granulocyte and basophil, as well as the animal models of BALB/c mouse, C3H/HeJ mouse, and BN rat. We also introduced zebrafish, a promising model organism for investigating immunity though lacking direct applications in food allergy to date, and focused on traumatic inflammation, bacterial infection and viral infection models. In addition, we also summarized the clinical diagnostic research methods for food allergy. The elucidation of these topics will help researchers to understand the characteristics and mechanisms of various models and thus select the proper models for particular study, so as to support further investigations of food allergy.
  • Effects of a flavonoid-enriched orange peel extract against type 2
           diabetes in the obese ZDF rat model

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): Alexander Gosslau, Emmanuel Zachariah, Shiming Li, Chi-Tang Ho Effects of an enriched orange peel extract (OPE) against type 2 diabetes (T2D) were analyzed in ZDF rats which were hyperglycemic, dyslipidemic and express pro-inflammatory markers. Glucose related parameters were lowered in the lean control and metformin group as compared to ZDF vehicle controls. OPE was well tolerated and induced a decline in fasted blood glucose and increase levels of fed glucose although to a lesser degree as compared to metformin. However, OPE did not improve glucose tolerance but showed significantly elevated glucose levels. Furthermore, OPE treatment caused an increase of free fatty acids in a dose-responsive manner as well as elevated levels of cholesterol and LDL. The analysis of inflammatory mediators revealed a significant down-regulation of COX-2, ICAM-1, and TNF-α in epididymal adipose tissue in response to OPE to a higher degree as compared to ibuprofen. In whole blood, IL-4 was upregulated in a dose-responsive manner as measured by ELISA. In summary, lipophilic OPE showed strong anti-inflammatory effects in adipose tissue, ambivalent effects against hyperglycemia, whereas hyperlipidemia was increased. Our study emphasize the complexity of anti-diabetic regimen suggesting a treatment with OPE to reduce inflammation in adipose tissue in combination with antidiabetic therapeutics as promising strategy against T2D.
  • Hypolipidemic effect of coffee silver skin in rats fed a high-fat diet

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): Ayman Mohammed El-Anany, Rehab Farouk M. Ali The present study was conducted to evaluate the hypolipidemic effects of coffee silver skin (CSS) supplementation in rats fed a highfat diet (HFD). A total of 40 albino rats were used in the present study. The groups were as follows: Rats fed a normal diet, N group; high fat diet, HFD group; high fat diet +10% CSS, HFD 10; HFD + 15% CSS, HFD 15; HFD + 20% CSS, HFD 20; the diets were followed for 8 weeks. Blood samples were collected at the end of the experiment. At the time of sacrifice, the weights of heart, liver, kidneys, epididymal fat and retroperitoneal fat of the experimental rats with respect to body weight were recorded. The lipid parameter of the serum was recorded and liver and kidney function tests were conducted. Finally, a histopathological assay was performed on the liver and kidney tissues of the rats fed the tested diets. The weight gain of the rats fed a HFD supplemented with 10, 15 and 20% CSS was ∼1.05, 1.08 and 1.12 times lower than that of those rats fed HFD, respectively. The incorporation of CSS at a level of 20% reduced the increase in liver, kidney, epididymal fat and retroperitoneal fat weight by 17.84, 19.38, 47.23 and 18.00%, respectively, compared with HFD alone. HFD administration induced considerable increases in alanine aminotransferase, aspartate aminotransferase and alkaline phosphatase activities compared with the control group. The results also indicated that the HFD-fed rats exhibited increased levels of urea, uric acid and creatinine, by ∼26.38, 8.40 and 6.75%, respectively, compared with the control rats. With the exception of high-density lipoprotein cholesterol, all lipid fractions increased significantly in rats fed a HFD. The administration of a HFD induced marked pathological changes in the liver and kidneys of the rats. However, the incorporation of various levels of CSS in to a HFD reduced these changes. The results of the present study illustrate that the incorporation of CSS into HFDs reduces the hyperlipidemia effect of these diets.
  • Evaluation of renoprotective effect of Chinese chive extracts on
           adenine-induced chronic renal failure

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): Qiang-Ming Li, Jian-Ping Luo, Li-Hua Pan, Xue-Qiang Zha The renoprotective effects of Chinese chive water and ethanol extracts (CCWE and CCEE) on adenine-induced chronic renal failure (CRF) mice were evaluated in this study. Results showed that the renal pathological damages and the enhancement of serum creatinine and blood urea nitrogen of CRF mice could be significantly alleviated by the treatment of CCWE, but not CCEE. When the concentration of CCWE reached 200 mg/kg/day, the area of renal pathological damage was decreased to the 48.1% of model group, and the levels of serum creatinine and blood urea nitrogen were decreased to the 87.7% and 83.9% of model group, respectively. Meanwhile, it could be found that renal oxidative stress and inflammation of CRF mice were remarkably inhibited by CCWE. These results indicated CCWE could improve the kidney function of CRF mice via enhancing antioxidant ability and inhibiting inflammation, and was the main renoprotective fraction of Chinese chive.
  • Procoagulant constituents from Cordyceps militaris

    • Abstract: Publication date: December 2018Source: Food Science and Human Wellness, Volume 7, Issue 4Author(s): Juanjuan Zhang, Wei Zhang, Zhenhua Yin, Changqin Li, Wenyi Kang Cordyceps militaris, belongs to Clavicipitaceae family, was investigated for its chemical compounds, and six compounds were isolated and purified by silica gel column chromatography, Sephadex LH-20 and recrystallization, and their structures were elucidated by spectral techniques and physicochemical properties as ergosterol (1), adenosine (2), cordycepin (3), ergosterol peroxide (4), tetracosanoic acid 2,3-dihydroxypropylester (5), mannitol (6). Procoagulant activity was screened by assaying the activated partial thromboplastin time (APTT), prothrombin time (PT), thrombin time (TT) and fibrinogen (FIB) in vitro. The results indicated that ergosterol, adenosine, cordycepin, ergosterol peroxide and mannitol showed strong procoagulant activity.
  • Rapid and easy determination of morphine in chafing dish condiments with
           colloidal gold labeling based lateral flow strips

    • Abstract: Publication date: Available online 30 November 2018Source: Food Science and Human WellnessAuthor(s): Wei Chen, Xin-ni Li, Qian Wu, Li Yao, Jianguo Xu In order to enhance the flavor of chafing dish and increase the attraction of consumers, the poppy shell is reported to be illegally added to the condiments of chafing dish. In this research, a rapid, simple, and convenient method based on the classic immunochromatographic lateral flow strip (LFS) with gold nanoparticles (GNPs) labeling was developed for easy monitoring of morphine (MOP), an effective component of poppy shell. Under optimized conditions, this developed LFS can well realize the detection of target MOP in the condiments of chafing dish in less than 10 min without any complicated pre-treatments. The limit of detection (LOD) can be achieved as low as 0.1 ppb for standard MOP or the MOP spiked condiments of chafing dish. All these results of the research strongly demonstrate that this established LFS method can be successfully applied in practical rapid and accurate on-site screening of poppy shell in condiments of chafing dish.
  • Corn phytochemicals and their health benefits

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Sheng Siyuan, Li Tong, RuiHai Liu Whole grain has a wide range of phytochemicals exhibiting health benefits of lowering risk of chronic diseases. As commonly consumed grain product, corn has unique profiles of nutrients and phytochemicals when compared with other whole grains. Corn nutrients and phytochemicals include vitamins (A, B, E, and K), minerals (Mg, P, and K), phenolic acids (ferulic acid, coumaric acid, and syringic acid), carotenoids and flavonoids (anthocyanins), and dietary fiber. More and more scientific evidences have shown that regular consumption of whole grain corn lowers the risk of developing chronic diseases such as cardiovascular disease, type 2 diabetes, and obesity and improves digestive health. Further studies on bioactive compounds of corn related to health are needed.
  • Nutraceutical support for respiratory diseases

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Yu-Ya Hwang, Yuan-Soon Ho Respiratory diseases have been a major health concern for human beings since several decades. Soothing the irritated nasal passages and airways had been a mutual necessity in multiple ancient cultures. In ancient China, herbs were largely used to help deal with cough and reduce mucus, thereby maintaining respiratory health. In India, knowledge of herb-related remedies passed down through generations. In the human society, freshly prepared herb ointments, including air-dried herbs, and boiled herbal soups have had a long history of combining botanical nutrients with local cuisine.Although the use of herbs and natural products from plants (NPFPs) has been primarily cited in reviews based on modern respiratory diseases, the concept of soothing and alleviating disease progression or reducing mucus production has been highly valued. Nevertheless, only a few herbs could directly disrupt the irreversible fibrotic progression. On the other hand, natural products from animals (NPFAs) have more potential in disrupting procollagen or extracellular matrix deposition. Due to these reasons, NPFAs could be considered as important functional foods for patients with respiratory diseases. In this article, we provide a review of both NPFAs and NPFPs that are adjuvant to respiratory health.
  • Prophylactic effect of Kudingcha polyphenols on oxazolone induced colitis
           through its antioxidant capacities

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Xingyao Long, Yanni Pan, Xin Zhao This research the preventive effect of Kudingcha polyphenols (Kp) on colitis based on animal experiments. Experimental mice divided into four groups, including normal group, model group, low-concentration Kp (LKP) group and high-concentration Kp (HKP) group, and they all smeared and given 0.15 mL 1% oxazolone solution by lavage to induce BALB/c mice colitis. DAI, colon weight/length ratio, serum levels of cytokines, related antioxidant activities of colon tissues such, and the mRNA expressions. The experimental results show that KP can significantly (p 
  • Study of interaction between metal ions and quercetin

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Taiane Souza de Castilho, Tatiane Brescovites Matias, Keller Paulo Nicolini, Jaqueline Nicolini A displacement test based on the interaction between the flavonoid quercetin and an excess of metal chloride allows the determination of the binding constant for the reaction between quercetin and Ca2+, Mg2+ and Ni2+. The values obtained were 2.20 ± 1.77 × 103 for Ca2+, 1.37 ± 0.59 × 103 for Mg2+ and 7.03 ± 1.04 × 104 for Ni2+, and all interactions showed type 1:1 stoichiometry, as determined by titration and by the method of continuous variations (Job’s method). The complexion effect was observed qualitatively through a colorimetric change in the medium (yellow → neon yellow) and spectroscopically through a bathochromic shift in the absorption band of quercetin in the presence of metals. This investigation serves as a tool for the development and testing of materials capable of capturing toxic metal ions or favoring the absorption of beneficial ions (in relation to the human metabolism) through the construction of efficient bioorganic systems. The results reported herein allow understanding of this detection system, indicating the following ascending order of the binding constants (Mg2+ 
  • The feasibility study of natural pigments as food colorants and seasonings
           pigments safety on dried tofu coloring

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Wei-Sheng Lin, Pei Hua He, Chi-Fai Chau, Bo-Kang Liou, Shiming Li, Min-Hsiung Pan In order to improve appetite, attract consumers and even conform to the food culture, food coloring has become one of the necessary links in modern food processing. For example, dried-tofu will be colored by adding artificial food colors (AFCs) such as sunset yellow, cochineal red A or other seasonings like soy sauce. However, the dispute persists about whether AFCs are harmful to health. Some studies indicate AFCs affect children’s intelligence and attention, cause hyperactivity, and allergy when children consumed ≥ 50 mg. In addition, researches showed that chemical soy sauce produces a trace of methylglyoxal (MGO) in the manufacturing process, which is related to diseases such as oxidative stress, diabetes, and cognitive deterioration. Therefore, natural pigments are relatively new and promising strategy for replacing high-risk AFCs. Thus, the objective of this study was to use dried-tofu as a natural colorants coloring screening platform, through the concept of three primary colors to discuss the coloring effects of natural colorants in Taiwan in double –phase (liquid phase to solid phase) food coloring system and assess the effects of MGO on PC12 neuron cellular morphology and cell cycle at the dietary exposure in soy sauce. Our results showed that formula G:R = 0.2:0.8 and C:R = 0.08:0.92 were coloring by combined natural colorants had the same eye sensory quality acceptance of consumer and had the intention to purchase. Furthermore, the results from the PC12 cell suggested that dietary exposure of methylglyoxal (
  • Behavioral assessment of hippocampal function following dietary

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Klaus W. Lange, Ewelina Stollberg, Yukiko Nakamura, Joachim Hauser Pattern separation keeps items distinct in memory and is mediated by the hippocampus. A relationship between hippocampal function and diet quality has been suggested by findings in both humans and animals. In the present study, rats were fed over seven generations a diet containing increased amounts of sugar and saturated fatty acids, reduced levels of polyunsaturated fatty acids and an increased ratio of omega-6/omega-3 fatty acids (“Western” diet). Spatial pattern separation (or local discrimination) performance of these animals was compared with that of rats fed a standard diet. A separation-dependent difference between the standard and Western diet groups was found in the number of discriminations performed in the pattern separation task, with rats of the “Western” group performing fewer discriminations. The present results suggest that behavioral assessment of spatial pattern separation can detect effects of dietary interventions in rats and that pattern separation can be impaired by transgenerational administration of a “Western” diet. Future studies should determine which components of this diet induce the memory impairments related to the hippocampus. The translational relevance of these findings in regard to mental disorders such as dementia and depression needs to be investigated.
  • Role of calpain system in meat tenderness: A review

    • Abstract: Publication date: September 2018Source: Food Science and Human Wellness, Volume 7, Issue 3Author(s): Z.F. Bhat, James D. Morton, Susan L. Mason, Alaa El-Din A. Bekhit Aging is a popular method used by meat industry for improving the sensory attributes of meat. Despite the advent of many novel technologies, aging has not lost its charm and is still widely used commercially as a post-mortem intervention for tenderization. Aging improves the tenderness of meat through disruption of the muscle structure by intracellular proteolytic systems. Muscles undergo various molecular changes that cause proteolysis of key myofibrillar and cytoskeletal proteins, disrupting the overall integrity of muscle cells. Although several endogenous proteolytic systems are capable of post-mortem proteolysis, a great body of scientific evidence supports a major role for the calpain system. Calpains are intracellular calcium-dependent cysteine proteases found in most eukaryotes. At least three calpains (μ- and m-calpains and calpain 3) and calpastatin, their specific endogenous inhibitor, are found in muscle. They are known to be involved in the proteolysis of functionally relevant structural proteins such as the myofibrillar proteins and cytoskeletal anchorage complexes. These ubiquitous proteases are also present in mitochondria and play important roles in a variety of pathophysiological conditions including apoptotic and necrotic cell death phenomena. This review discusses the role and contribution of the calpain system and the factors that influence calpain activity during aging.
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