Authors:A. Di Bello; A. Buonavoglia, D. Franchini, C. Valastro, G. Ventrella, M. F. Greco, M. Corrente Pages: n/a - n/a Abstract: OBJECTIVE
Red complex bacteria (Treponema denticola, Tannerella forsythia and Porphyromonas gingivalis) play a major role in the aetiology of periodontal disease in humans. This study was designed to evaluate the association of such bacteria with periodontal disease in dogs.
Seventy‐three subgingival samples taken from dogs ranging from 2 months to 12 years (median age 4 years) were tested for red complex bacteria using a polymerase chain reaction assay.
Thirty‐six of 73 (49 · 3%) dogs were found to be positive for T. forsythia and P. gingivalis. Dogs with gingivitis or periodontitis were more likely to be infected with T. forsythia and P. gingivalis [odds ratio (OR) 5 · 4 (confidence interval (CI) 1 · 9‐15 · 6), P = 0 · 002] than healthy animals. Only 3 (4 · 1%) of 73 samples were positive for red complex bacteria, but the association with periodontal disease was not significant.
Conclusion And Clinical Relevance
The results indicate that involvement of red complex bacteria in periodontal disease in dogs is similar to that observed in humans. Only the concurrent presence of T. forsythia and P. gingivalis were correlated to periodontal disease in dogs in this study. PubDate: 2014-01-23T01:08:14.198731-05: DOI: 10.1111/jsap.12179
Authors:R. V. Ramos; B. P. Monteiro‐Steagall, P. V. M. Steagall Pages: n/a - n/a Abstract: OBJECTIVES
The aim of this study was to report the management and complications of anaesthesia in dogs undergoing balloon valvuloplasty.
A retrospective review of medical records of dogs that were diagnosed with pulmonic stenosis and undergoing balloon valvuloplasty between 2000 and 2012.
Thirty‐nine cases were identified (28 males and 11 females). Median (range) age and bodyweight was 6 (4 to 48) months and 11 · 5 (2 · 0 to 30 · 3) kg, respectively. The most commonly represented breeds included mixed breed (n = 7, 17 · 9%) and English bulldog (n = 6, 15 · 3%). Anaesthesia was induced most commonly with intravenous administration of ketamine‐diazepam (n = 8, 20 · 5%), propofol‐diazepam (n = 8, 20 · 5%), or propofol‐midazolam‐lidocaine (n = 6, 15 · 4%), and maintained with isoflurane in combination with fentanyl or lidocaine. Anaesthetic and surgery times (mean ± sd) were 268 · 5 ±54 minutes and 193 · 2 ±50 minutes, respectively. The most common intraoperative complications were hypotension (n = 19, 48 · 7%), bradycardia (n = 8, 20 · 5%) and desaturation (n = 7, 17 · 9%). Cardiac arrhythmias were observed in 21 (53 · 8%) dogs. Death occurred in one (2 · 6%) dog due to severe hypotension after ballooning followed by cardiac arrest.
Successful anaesthesia can be performed in young dogs with pulmonic stenosis undergoing balloon valvuloplasty. Management of anaesthesia requires intense monitoring and immediate treatment of complications. Anaesthetic risk increases during ballooning and may result in cardiac arrest. PubDate: 2014-01-23T01:08:10.362277-05: DOI: 10.1111/jsap.12182
Authors:P. Higgs; M. Costa, A. Freke, K. Papasouliotis Pages: n/a - n/a Abstract: OBJECTIVES
The AIA‐360 (Tosoh Corporation) is an automated immunoassay analyser. The aims of this study were to estimate the precision of thyroxine and cortisol AIA‐360 immunoassays in canine and feline samples and to compare the results produced with those obtained by a chemiluminescence analyser (Immulite® 1000, Siemens).
Blood samples from 240 clinical cases (60 dogs and 60 cats for both thyroxine and cortisol) were analysed using both instruments.
Deming regression calculations showed excellent correlation (thyroxine, canine rs = 0 · 94, feline rs = 0 · 97; cortisol, canine rs = 0 · 97, feline rs = 0 · 97). Agreement between the two instruments was examined by Bland–Altman difference plots, which identified wide confidence intervals and outliers for thyroxine (canine n = 6, feline n = 4) and cortisol (canine n = 3, feline n = 4) results. Inter/intra‐run precision of the AIA‐360 was excellent for both cortisol and thyroxine (coefficients of variation PubDate: 2014-01-20T01:52:36.966039-05: DOI: 10.1111/jsap.12181
Authors:B. Gindiciosi; V. Palus, S. Eminaga, E. Villiers, G. Bruto Cherubini Pages: n/a - n/a Abstract: Objective
To determine serum bromide concentrations following an oral loading dose in dogs.
Retrospective review of clinical records of dogs suffering from seizures that were treated with bromide. A loading dose of 600 mg/kg potassium bromide was administered orally in 17 to 48 hours together with a maintenance dose of 30 mg/kg/day. Blood samples were collected within 24 hours after completing the protocol and serum bromide concentrations were determined by ultra‐violet gold chloride colorimetric assay.
Thirty‐eight dogs were included in the study. The median age was 3 (range, 0 · 2 to 10) years and bodyweight 21 · 8 (3 · 45 to 46 · 2) kg. The median serum bromide concentration was 1 · 26 (0 · 74 to 3 · 6) mg/mL. Thirty‐two dogs (84 · 2%) had serum bromide concentrations within the therapeutic interval (1 to 3 mg/mL). The serum concentration in five dogs (13 · 2%) was just under the minimal therapeutic value and in one dog (2 · 6%) it exceeded the maximal therapeutic value (3 · 6 mg/mL).
Following this oral loading dose protocol, serum bromide concentrations reach the therapeutic range in the majority of dogs. This indicates that the suggested protocol is effective in achieving therapeutic concentrations rapidly in epileptic dogs. PubDate: 2014-01-16T22:42:01.982483-05: DOI: 10.1111/jsap.12173
Authors:E. West; D. Bardell, J. Mark Senior Pages: n/a - n/a Abstract: OBJECTIVES
A prospective study to evaluate agreement and precision of a new point‐of‐care portable analyser, the EPOC analyser, compared with the i‐STAT analyser in canine blood.
Blood samples (68 venous and 32 arterial) were obtained from 63 client‐owned dogs for clinical reasons and surplus blood was used to analyse agreement between the EPOC and i‐STAT analysers. Precision of the EPOC analyser was also assessed by repeat analysis of 20 samples. Measured analytes included pH, partial pressures of carbon dioxide and oxygen and concentrations of sodium, potassium, ionised calcium, glucose and haematocrit. Haemoglobin, base excess, bicarbonate and saturation of haemoglobin with oxygen were calculated.
EPOC precision was acceptable, but agreement was poor for sodium, haematocrit, haemoglobin and base excess. Overall, method comparison was poor for pH, partial pressure of oxygen, sodium, haematocrit, haemoglobin and base excess.
The EPOC analyser is useful for dogs, although clinically significant differences between the EPOC and i‐STAT analysers exist for some analytes, and as such these analysers should not be used interchangeably. PubDate: 2014-01-16T00:12:46.607024-05: DOI: 10.1111/jsap.12177
Authors:H. D. Plickert; A. Tichy, R. A. Hirt Pages: n/a - n/a Abstract: OBJECTIVES
To compare characteristics of nasal discharge caused by different intranasal aetiologies in dogs.
Medical records of 105 dogs with nasal discharge due to intranasal disease were retrospectively reviewed with special focus on composition, severity, duration and localisation of discharge. On the basis of diagnostic findings, cases were classified into different disease groups and characteristics of discharge were compared between groups.
Cases were classified as having non‐specific rhinitis (n=42), nasal neoplasia (n=23), foreign bodies (n=21), nasal mycosis (n=7) and miscellaneous disorders (n=13). Dogs with foreign bodies or nasal mycosis were significantly younger. Mucous components of discharge occurred more often in non‐specific rhinitis and nasal neoplasia, although haemorrhagic components predominated in nasal neoplasia when discharge lasted ê14 days. Pure or mixed haemorrhagic discharge was significantly more common with nasal neoplasia, foreign bodies and nasal mycosis. Purulent components were associated with longer duration of discharge and predominantly seen in non‐specific rhinitis and foreign bodies. Dogs with foreign bodies were presented earlier and sneezing was more frequent. Nasal stridor was significantly more often observed in dogs with nasal neoplasia.
Characteristics of nasal discharge and associated clinical signs might aid in planning the diagnostic approach, but a combination of diagnostic techniques is still required to confirm a diagnosis. PubDate: 2014-01-15T05:13:20.771775-05: DOI: 10.1111/jsap.12175
Authors:P. Silvestrini; A. Zoia, M. Planellas, X. Roura, J. Pastor, J. J. Cerón, M. Caldin Pages: n/a - n/a Abstract: OBJECTIVE
To investigate the iron status, its relationship with C‐reactive protein and the prognostic value of both in canine leishmaniasis.
Eighty‐six dogs with leishmaniasis and two control groups (healthy dogs and dogs with diseases other than leishmaniasis) were selected. Iron status indicators and C‐reactive protein were compared between the three groups. Correlations between C‐reactive protein and iron, ferritin and total iron‐binding capacity were evaluated in dogs with leishmaniasis. Iron, total iron‐binding capacity and ferritin were compared between dogs stratified according to similar C‐reactive protein concentrations. The mortality rate at 30 days post‐diagnosis was compared between groups. Iron status indicators and C‐reactive protein were compared between survivors and non‐survivors.
Dogs with leishmaniasis had lower iron and total iron‐binding capacity and higher ferritin and C‐reactive protein. There was a significant but low correlation of C‐reactive protein with iron, ferritin and total iron‐binding capacity. Dogs with leishmaniasis had decreased iron and total iron‐binding capacity and increased ferritin compared to other ill patients with similar C‐reactive protein concentrations. Mortality was not significantly different between groups but non‐survivor dogs with leishmaniasis had higher C‐reactive protein and lower total iron‐binding capacity.
Inflammation contributes to the iron status alterations found in canine leishmaniasis but other mechanisms are likely involved. Low total iron‐binding capacity and increased C‐reactive protein are risk factors for outcome in canine leishmaniasis. PubDate: 2013-12-27T22:58:55.826374-05: DOI: 10.1111/jsap.12172
Authors:C. Rohdin; H. T. Nyman, P. Wohlsein, K. Hultin Jäderlund Pages: n/a - n/a Abstract: Seven related young pugs were diagnosed with cervical spinal intradural arachnoid cysts by magnetic resonance imaging (n = 6) and myelography (n = 1). All dogs were presented with skin abrasions on their thoracic limbs and non‐painful neurological deficits, indicating a C1‐T2 myelopathy. In all six dogs examined by magnetic resonance imaging not only the spinal arachnoid cyst but also a concomitant, most likely secondary, syringohydromyelia was confirmed. Pedigree analysis suggested a genetic predisposition for spinal arachnoid cysts in this family of pugs. Generalised proprioceptive deficits more pronounced in the thoracic limbs suggesting a focal cervical spinal cord lesion, with concomitant skin abrasions on the dorsal aspect of the thoracic limbs in a young pug, should alert veterinarians to the possibility of cervical spinal arachnoid cysts. PubDate: 2013-12-27T07:39:01.766436-05: DOI: 10.1111/jsap.12167
Authors:V. Black; L. Garosi, M. Lowrie, R. J. Harvey, J. Gale Pages: n/a - n/a Abstract: OBJECTIVES
To characterise the phenotype of Border terriers suspected to be affected by canine epileptoid cramping syndrome and to identify possible contributing factors.
Owners of Border terriers with suspected canine epileptoid cramping syndrome were invited to complete an online questionnaire. The results of these responses were collated and analysed.
Twenty‐nine Border terriers were included. Most affected dogs had their first episode before 3 years of age (range: 0·2 to 7·0 years). The majority of episodes lasted between 2 and 30 minutes (range: 0·5 to 150 minutes). The most frequent observations during the episodes were difficulty in walking (27 of 29), mild tremor (21 of 29) and dystonia (22 of 29). Episodes most frequently affected all four limbs (25 of 29) and the head and neck (21 of 29). Borborygmi were reported during episodes in 11 of 29 dogs. Episodes of vomiting and diarrhoea occurred in 14 of 29, with 50% of these being immediately before or after episodes of canine epileptoid cramping syndrome (7 of 14). Most owners (26 of 29) had changed their dog's diet, with approximately 50% (14 of 26) reporting a subsequent reduction in the frequency of episodes.
This study demonstrates similarities in the phenotype of canine epileptoid cramping syndrome to paroxysmal dystonic choreoathetosis, a paroxysmal dyskinesia reported in humans. This disorder appears to be associated with gastrointestinal signs in some dogs and appears at least partially responsive to dietary adjustments. PubDate: 2013-12-26T00:15:37.985632-05: DOI: 10.1111/jsap.12170
Authors:L. Janssens; M. De Ridder, G. Verhoeven, I. Gielen, H. Bree Pages: n/a - n/a Abstract: OBJECTIVES
The aim of this study was to compare Norberg angle, linear femoral overlap and surface femoral overlap in radiographs of hips accepted for official hip dysplasia screening.
Radiographs of 100 dogs (200 hips) were reviewed. The three measurements were performed in each hip according to previously described methods and thereafter correlated.
Intra‐ and inter‐observer reliability was very high (all >85%). The linear correlation between Norberg angle and linear femoral overlap or surface femoral overlap was 0·40 and 0·41, respectively. The linear correlation between linear femoral overlap and surface femoral overlap was 0·84.
Norberg angle cannot be compared with surface femoral overlap or linear femoral overlap, and a mathematical formula could not be computed for the comparison. PubDate: 2013-12-24T03:56:51.808425-05: DOI: 10.1111/jsap.12171
Authors:K. W. Delk; D. Eshar, E. Garcia, K. Harkin Pages: n/a - n/a Abstract: A one‐year‐old African pygmy hedgehog (Atelerix albiventris) was evaluated for severe respiratory distress. Physical examination findings included marked dyspnoea, cyanosis and tachypnoea. Radiographic findings included an enlarged heart and pulmonary oedema, and dilated cardiomyopathy was confirmed via echocardiogram. The patient was treated for congestive heart failure because of dilated cardiomyopathy with furosemide, enalapril, pimobendan and l‐carnitine. Within 24 hours of treatment, the pulmonary oedema and cyanosis had resolved. Following discharge, clinical improvement was noted by the owner and echocardiogram confirmed improved fractional shortening. Cardiomyopathy has been reported at post‐mortem examination in hedgehogs, but there are no reports of ante‐mortem diagnosis and treatment. Performing baseline cardiac assessment in hedgehogs is recommended, and treatment with l‐carnitine and pimobendan may improve outcome, as carnitine deficiency is a possible cause of cardiomyopathy in hedgehogs. Successful emergency treatment of congestive heart failure in the hedgehog of this report may be effective for other hedgehogs presented with similar clinical signs. PubDate: 2013-12-23T22:53:03.26872-05:0 DOI: 10.1111/jsap.12169
Authors:P. D. Mayhew Pages: n/a - n/a Abstract: Advancements in soft tissue minimally invasive surgery have been rapid and comprehensive since its inception in human medicine approximately 25 years ago. From its origins in traditional laparoscopy, followed rapidly by video‐assisted thoracoscopic surgery, minimally invasive surgery in human medicine has evolved through a number of different platforms that now include single‐port approach devices, robotic surgery as well as natural orifice transluminal endosurgery. Whilst some of these remain beyond the reach of veterinary medicine for now, largely because of technical challenges and the prohibitive costs of some single‐use disposable components, veterinary minimally invasive surgery is advancing rapidly allowing our small animal patients to benefit from some of the many documented advantages that a minimally invasive approach affords the patient. PubDate: 2013-12-23T22:51:53.952394-05: DOI: 10.1111/jsap.12164
Authors:F. Macrì; F. Ciotola, G. Rapisarda, G. Lanteri, S. Albarella, G. Aiudi, L. Liotta, F. Marino Pages: n/a - n/a Abstract: A case of non‐syndromic, complete syndactyly involving all four limbs is described in a three‐month‐old male crossbreed dog for the first time. Syndactyly is a rare condition in most animal species, in dogs it has been infrequently reported. Findings of clinical, radiographic and cytogenetic analyses are described and demonstrate probably for the first time that numerical and structural chromosome aberrations are not involved in the pathogenesis of this case of syndactyly. PubDate: 2013-12-17T22:58:15.240232-05: DOI: 10.1111/jsap.12165
Authors:D. Carwardine; E. Friend, M. Toscano, K. Bowlt Pages: n/a - n/a Abstract: OBJECTIVES
Feline injection site sarcomas are therapeutically challenging because of their locally invasive nature. Several protocols recommend that the two perceived high‐risk adjuvanted vaccines should be administered into distinct anatomical sites (“left hind leg leukaemia, right hind leg rabies”), which should aid surgical resection. This has resulted in a change in tumour distribution with an increased proportion situated caudal to the diaphragm when such a policy is adopted. The aim of this study was to determine UK cat owners’ attitudes towards surgical treatments of different anatomical regions.
A cross‐sectional study of an anonymous convenience sample of UK cat owners was conducted from September to December, 2012 using an internet‐based survey.
There were a total of 208 respondents: 39% would pursue surgery regardless of tumour site. One percent would not pursue surgery. Of the remainder, respondents would not allow amputation of the forelimb (20%), hindlimb (15%) or tail (15%). Twenty‐six, 32 and 27% would not have surgical treatment of the inter‐scapular region, chest or abdomen, respectively. The majority of respondents were willing to travel up to 100 miles for radiotherapy or chemotherapy (66 and 69%, respectively).
The current feline vaccine site recommendations may not be appropriate for UK cat owners. PubDate: 2013-12-13T01:34:25.293141-05: DOI: 10.1111/jsap.12162
Authors:R. Bouabdallah; P. Moissonnier, F. Delisle, P. De Fornel, M. Manassero, M. Maaoui, P. Fayolle, V. Viateau Pages: n/a - n/a Abstract: OBJECTIVES
To evaluate a rational decision‐making approach based on preoperative computed tomography for surgical planning in dogs and cats with recurrent draining tracts.
Retrospective evaluation of case records of animals that underwent preoperative computed tomography for surgical treatment of thoracic/abdominal recurrent draining tracts. Cases were classified according to whether a source of inflammation and/or infection, in particular foreign bodies, was identified (group 1), suspected (group 2) or neither identified nor suspected (group 3) at computed tomography. Surgery consisted of removal of the source of inflammation and/or infection (group 1), debridement or abscess drainage (group 2) or en bloc resection of diseased tissues (group 3). Clinical outcome was evaluated at least 12 months after surgery.
A source of inflammation and/or infection was found in 100% (8 of 8), 41% (7 of 17) and 25% (3 of 12) of cases in groups 1, 2 and 3, respectively. Recurrent draining tracts resolved in 100% (8 of 8), 94% (16 of 17) and 92% (11 of 12) of cases in groups 1, 2 and 3, respectively.
The proposed strategy provided a 95% (35 of 37) cure rate, after a single procedure in 81% (30 of 37) of cases. Recovery of a foreign body at surgery was not a prerequisite for the resolution of the recurrent draining tracts. PubDate: 2013-12-11T02:03:19.807195-05: DOI: 10.1111/jsap.12163
Authors:S. M. Rajaei; H. Khorram, M. Ansari Mood, S. Mashhadi Rafie, D. L. Williams Pages: n/a - n/a Abstract: Leeches are bloodsucking hermaphroditic parasites that attach to tissues using two muscular suckers, ingest large amounts of blood and may cause severe anaemia in the host. Two four‐month‐old mixed‐breed dogs (one bitch and one male) were referred with anorexia, retching, hypersalivation and bleeding from the oral cavity. On physical examination, two live leeches were detected on the ventral aspect of the tongue of the bitch and one in a similar position in the male. The leeches were gently detached and removed using Adson tissue forceps after applying vinegar over the area. Microcytic hypochromic anaemia was detected in the bitch and mild leukocytosis in the dog. One month after treatment both animals were re‐examined and a complete blood count was normal. Given that infestation with leeches as described here is associated with contaminated water, the use of clean and safe drinking water is recommended to avoid such diseases. PubDate: 2013-12-10T02:14:48.813786-05: DOI: 10.1111/jsap.12166
Authors:K. Bowlt; I. Cattin, J. Stewart Pages: n/a - n/a Abstract: Feline hyperthyroidism can be treated medically, surgically or with radioactive iodine. Carbimazole inhibits both triiodothyronine and thyroxine synthesis in the thyroid gland and reported side effects include mild eosinophilia, leucopenia and lymphocytosis, thrombocytopenia, elevated liver enzyme activities, gastrointestinal signs and skin abnormalities. This case report describes a cat with carbimazole‐associated apparent hypersensitivity vasculitis causing digital and tail necrosis, with multiple renal infarcts. Withdrawal of carbimazole resulted in stable disease. PubDate: 2013-11-21T01:40:22.666913-05: DOI: 10.1111/jsap.12154
Authors:K. Vanderperren; H. Haers, E. Van der Vekens, E. Stock, D. Paepe, S. Daminet, J. H. Saunders Pages: n/a - n/a Abstract: Canine pancreatic tumours are rare compared to human medicine and the detection and differentiation of pancreatic neoplasia is challenging with B‐mode ultrasonography, which often leads to late clinical diagnosis and poor prognosis. This case report describes the findings of contrast‐enhanced ultrasonography in four dogs with pancreatic adenocarcinoma or insulinoma. B‐mode ultrasonography of the pancreas revealed a hypoechoic nodule in three dogs and heterogenous tissue in one dog. Contrast‐enhanced ultrasonography was able to differentiate between two tumour types: adenocarcinomas showed hypoechoic and hypovascular lesions, whereas insulinomas showed uniformly hypervascular lesions. Contrast‐enhanced ultrasonography findings were confirmed by cytology and/or histopathology. The results demonstrated that contrast‐enhanced ultrasonography was able to establish different enhancement patterns between exocrine (adenocarcinoma) and endocrine (insulinoma) tumours in dogs. PubDate: 2013-11-01T01:53:23.842384-05: DOI: 10.1111/jsap.12153
Authors:F. Swinbourne; E. Kulendra, K. Smith, C. Leo, G. Ter Haar Pages: n/a - n/a Abstract: A 4·5‐year‐old, female neutered Leonberger was presented with a 2‐month history of sneezing, nasal discharge and epistaxis. A presumptive diagnosis of nasal aspergillosis was made based on a suspected (fungal) granuloma on rhinoscopic examination and fungal hyphae on cytological examination. A poor response to targeted therapy was observed and computed tomography 16 months after initial presentation revealed a progressive, locally invasive mass lesion. Histopathological and immunohistochemical analysis of deep surgical biopsies revealed a spindle cell population and a plasma cell rich inflammatory infiltrate, with diffuse expression of vimentin, supporting a diagnosis of inflammatory myofibroblastic tumour. Complete resolution of the nasal discharge and reduced sneezing frequency was reported 9 months post‐surgical debridement via rhinotomy. To the authors’ knowledge, this is the first report of IMT in the nasal cavity of a dog. IMT should be considered when presented with a nasal mass lesion, particularly if histopathological features and clinical course are inconsistent. PubDate: 2013-10-09T05:50:22.225914-05: DOI: 10.1111/jsap.12140
Authors:V. De monte; F. Staffieri, F. Birettoni, A. Bufalari Pages: n/a - n/a Abstract: An 11‐year‐old male German shepherd dog was referred for possible pacemaker implantation. A routine 6‐lead electrocardiogram revealed a third‐degree atrio‐ventricular block with a heart rate of 40 to 45 beats/minute. A transvenous pacemaker implantation procedure was scheduled. The dog was premedicated with 10 µg/kg acepromazine and 5 mg/kg pethidine. A dose of 5 mg/kg ketamine and 0·2 mg/kg diazepam were used for induction and isoflurane in O2 and a constant rate infusion of ketamine (20 to 30 µg/kg/minute) were administered for maintenance of general anaesthesia. Due to a twiddler's syndrome, the pacemaker had to be repositioned. For the second procedure, the same protocol was employed except for a lower dose of ketamine both for induction (3 mg/kg) and constant rate infusion (10 to 15 µg/kg/minute). Ketamine appeared to be useful for both management of anaesthesia and cardiac pacemaker implantation in the absence of a temporary pacemaker. PubDate: 2013-10-09T05:25:33.384746-05: DOI: 10.1111/jsap.12139
Authors:E. Donzel; E. Reyes‐Gomez, S. Chahory Pages: n/a - n/a Abstract: A three‐year‐old male neutered domestic shorthair cat was presented for loss of vision associated with hyperthermia, lethargy and anorexia. Ophthalmic examination revealed a bilateral panuveitis. Cytological examination of aqueous and vitreous humours was performed and revealed a suppurative inflammation associated with numerous cocci. Enterococcus faecalis was identified by bacterial culture from aqueous and vitreous humour. No primary infection site was identified. Active uveitis resolved after systemic antibiotic therapy, but the vision loss was permanent. To the authors’ knowledge, this is the first reported case of endogenous bacterial endophthalmitis secondary to E. faecalis infection in a cat. PubDate: 2013-09-13T05:38:04.849356-05: DOI: 10.1111/jsap.12136
Authors:N. A. Boynosky; L. B. Stokking Pages: n/a - n/a Abstract: Two cases of panniculitis associated with administration of potassium bromide in dogs are reported. Both dogs were treated with potassium bromide for idiopathic epilepsy for over 1 year. Dose increases in both cases were associated with panniculitis, characterised by painful subcutaneous nodules in a generalised distribution over the trunk. Nodule eruption waxed and waned in one dog and was persistent in the other. In both cases, panniculitis was accompanied by lethargy and pyrexia. Panniculitis, lethargy and pyrexia resolved and failed to recur after discontinuation of potassium bromide. No other cause of panniculitis could be determined for either dog. Panniculitis has been reported after administration of potassium bromide in humans and may be a form of drug‐induced erythema nodosum. To the authors’ knowledge, these are the first reports of potassium bromide‐associated panniculitis in dogs. PubDate: 2013-09-06T04:06:41.817477-05: DOI: 10.1111/jsap.12129
Authors:J. Aguiar; G. Mogridge, J. Hall Pages: n/a - n/a Abstract: A four‐month‐old, entire male guinea pig was presented for surgical repair of a closed oblique femoral fracture. Analgesia was provided with 30 µg/kg buprenorphine intramuscularly (im) four times a day and 0 · 3 mg/kg meloxicam subcutaneously once a day. The following day, anaesthesia was induced and maintained with 100 µg/kg medetomidine im, 20 mg/kg ketamine im, 30 µg/kg buprenorphine im and isoflurane in oxygen. Femoral and sciatic nerve blocks were performed with bupivacaine. The fracture was reduced and aligned using an intramedullary 1 · 4 mm K‐wire and a 3 metric polydioxanone cerclage. Three weeks postoperatively remodelling and callus formation was documented, with no evidence of complications. Complete union was present 14 weeks postoperatively. PubDate: 2013-02-09T07:45:15.818435-05: DOI: 10.1111/jsap.12033