for Journals by Title or ISSN
for Articles by Keywords
help
  Subjects -> PHYSICS (Total: 767 journals)
    - ELECTRICITY AND MAGNETISM (8 journals)
    - MECHANICS (20 journals)
    - NUCLEAR PHYSICS (44 journals)
    - OPTICS (91 journals)
    - PHYSICS (557 journals)
    - SOUND (18 journals)
    - THERMODYNAMICS (29 journals)

PHYSICS (557 journals)            First | 1 2 3 4 5 6 | Last

Open Journal of Fluid Dynamics     Open Access   (Followers: 3)
Open Journal of Microphysics     Open Access  
Optical Communications and Networking, IEEE/OSA Journal of     Hybrid Journal   (Followers: 4)
Optofluidics, Microfluidics and Nanofluidics     Open Access  
Organic Electronics     Hybrid Journal   (Followers: 3)
Organic Photonics and Photovoltaics     Open Access   (Followers: 2)
PAJ: A Journal of Performance and Art     Hybrid Journal   (Followers: 11)
Particle Physics Insights     Open Access   (Followers: 2)
Particuology     Hybrid Journal  
Pattern Recognition in Physics     Open Access   (Followers: 1)
Pergamon Materials Series     Full-text available via subscription  
Phase Transitions and Critical Phenomena     Full-text available via subscription   (Followers: 1)
Philosophical Magazine     Hybrid Journal   (Followers: 2)
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences     Full-text available via subscription   (Followers: 5)
Philosophy and Foundations of Physics     Full-text available via subscription  
Physica B: Condensed Matter     Hybrid Journal   (Followers: 5)
physica status solidi (a)     Hybrid Journal   (Followers: 1)
physica status solidi (b)     Hybrid Journal   (Followers: 1)
physica status solidi (c)     Hybrid Journal   (Followers: 1)
Physica Status Solidi - Rapid Research Letters     Hybrid Journal   (Followers: 1)
Physical Communication     Hybrid Journal  
Physical Review C     Full-text available via subscription   (Followers: 18)
Physical Review Special Topics - Physics Education Research     Open Access   (Followers: 6)
Physical Review X     Open Access   (Followers: 6)
Physical Sciences Data     Full-text available via subscription   (Followers: 1)
Physics - spotlighting exceptional research     Full-text available via subscription   (Followers: 1)
Physics and Chemistry of Glasses - European Journal of Glass Science and Technology Part B     Full-text available via subscription   (Followers: 2)
Physics and Chemistry of Liquids: An International Journal     Hybrid Journal   (Followers: 2)
Physics and Chemistry of the Earth, Parts A/B/C     Hybrid Journal   (Followers: 3)
Physics and Materials Chemistry     Open Access  
Physics Essays     Full-text available via subscription  
Physics in Medicine & Biology     Full-text available via subscription   (Followers: 9)
Physics in Perspective     Hybrid Journal   (Followers: 1)
Physics International     Open Access   (Followers: 2)
Physics Letters A     Hybrid Journal   (Followers: 10)
Physics Letters B     Open Access   (Followers: 3)
Physics of Fluids     Hybrid Journal   (Followers: 24)
Physics of Life Reviews     Hybrid Journal   (Followers: 1)
Physics of Plasmas     Hybrid Journal   (Followers: 6)
Physics of the Dark Universe     Open Access  
Physics of the Solid State     Hybrid Journal   (Followers: 3)
Physics of Wave Phenomena     Hybrid Journal   (Followers: 1)
Physics Procedia     Partially Free   (Followers: 1)
Physics Reports     Full-text available via subscription   (Followers: 2)
Physics Research International     Open Access   (Followers: 1)
Physics Today     Hybrid Journal   (Followers: 26)
Physics World     Full-text available via subscription   (Followers: 3)
Physics-Uspekhi     Full-text available via subscription  
Physik in unserer Zeit     Hybrid Journal  
Physik Journal     Hybrid Journal  
Plasma Physics Reports     Hybrid Journal   (Followers: 2)
Pramana     Open Access   (Followers: 9)
Preview     Hybrid Journal  
Proceedings of the National Academy of Sciences     Full-text available via subscription   (Followers: 524)
Proceedings of the National Academy of Sciences, India Section A     Hybrid Journal   (Followers: 3)
Progress in Materials Science     Hybrid Journal   (Followers: 20)
Progress in Planning     Hybrid Journal   (Followers: 1)
Progress of Theoretical and Experimental Physics     Open Access  
Quantum Electronics     Full-text available via subscription   (Followers: 3)
Quantum Measurements and Quantum Metrology     Open Access  
Quantum Studies : Mathematics and Foundations     Hybrid Journal  
Quarterly Journal of Mechanics and Applied Mathematics     Hybrid Journal   (Followers: 3)
Radiation Effects and Defects in Solids     Hybrid Journal   (Followers: 1)
Radiation Measurements     Hybrid Journal   (Followers: 2)
Radiation Physics and Chemistry     Hybrid Journal   (Followers: 1)
Radiation Protection Dosimetry     Hybrid Journal   (Followers: 2)
Radiation Research     Full-text available via subscription   (Followers: 3)
Radio Science     Full-text available via subscription   (Followers: 3)
Radiological Physics and Technology     Hybrid Journal   (Followers: 1)
Reflets de la physique     Full-text available via subscription  
Reports on Mathematical Physics     Full-text available via subscription  
Reports on Progress in Physics     Full-text available via subscription   (Followers: 2)
Research & Reviews : Journal of Physics     Full-text available via subscription  
Research in Drama Education     Hybrid Journal   (Followers: 11)
Research Journal of Physics     Open Access  
Results in Physics     Open Access   (Followers: 1)
Reviews in Mathematical Physics     Hybrid Journal  
Reviews of Accelerator Science and Technology     Hybrid Journal  
Reviews of Geophysics     Full-text available via subscription   (Followers: 19)
Reviews of Modern Physics     Full-text available via subscription   (Followers: 17)
Revista Colombiana de Física     Open Access  
Revista Mexicana de Astronomía y Astrofísica     Open Access  
Revista Mexicana de Física     Open Access  
Revista mexicana de física E     Open Access  
Rheologica Acta     Hybrid Journal   (Followers: 3)
Russian Journal of Mathematical Physics     Hybrid Journal  
Russian Journal of Nondestructive Testing     Hybrid Journal   (Followers: 1)
Russian Physics Journal     Hybrid Journal  
Samuel Beckett Today/Aujourd'hui     Full-text available via subscription   (Followers: 2)
Science and Technology of Nuclear Installations     Open Access   (Followers: 1)
Science China : Physics, Mechanics & Astronomy     Full-text available via subscription   (Followers: 1)
Science Foundation in China     Full-text available via subscription   (Followers: 2)
Scientific Journal of Physical Science     Open Access  
Scientific Reports     Open Access   (Followers: 10)
Selected Topics in Applied Earth Observations and Remote Sensing, IEEE Journal of     Hybrid Journal   (Followers: 17)
Sensor Letters     Full-text available via subscription   (Followers: 1)
Sensors and Actuators A: Physical     Hybrid Journal   (Followers: 46)
Services Computing, IEEE Transactions on     Hybrid Journal   (Followers: 3)
Shock and Vibration     Hybrid Journal   (Followers: 7)
Shock Waves     Hybrid Journal   (Followers: 4)

  First | 1 2 3 4 5 6 | Last

Journal Cover   Nature Communications
  [SJR: 5.041]   [H-I: 34]   [45 followers]  Follow
    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
   ISSN (Online) 2041-1723
   Published by Nature Publishing Group Homepage  [111 journals]
  • Weak linkage between the heaviest rainfall and tallest storms
    • Authors: Atsushi Hamada, Yukari N. Takayabu, Chuntao Liu, Edward J. Zipser
      Abstract: Conventionally, the heaviest rainfall is associated with the most intense storms, yet this relationship remains untested. Here, Hamada et al . analyse 11 years of radar observations from the topics and subtropics, and conclude that the heaviest rainfall is most commonly associated with less intense convection.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7213
       
  • Ambipolar zinc-polyiodide electrolyte for a high-energy density aqueous
           redox flow battery
    • Authors: Bin Li, Zimin Nie, M. Vijayakumar, Guosheng Li, Jun Liu, Vincent Sprenkle, Wei Wang
      Abstract: Conventional redox flow batteries have low energy densities. Here the authors present an aqueous redox flow battery with an ambipolar and bifunctional zinc-polyiodide electrolyte, which exhibits an energy density approaching to that of lithium ion batteries.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7303
       
  • Observation of long-lived interlayer excitons in monolayer
           MoSe2–WSe2 heterostructures
    • Authors: Pasqual Rivera, John R. Schaibley, Aaron M. Jones, Jason S. Ross, Sanfeng Wu, Grant Aivazian, Philip Klement, Kyle Seyler, Genevieve Clark, Nirmal J. Ghimire, Jiaqiang Yan, D. G. Mandrus, Wang Yao, Xiaodong Xu
      Abstract: Monolayer transition metal dichalcogenide heterostructures with type II band alignment have generated wide interest in device physics at the two-dimensional limit. Here, Rivera et al . observe interlayer excitons in vertically stacked MoSe2–WSe2 heterostructures and demonstrate tunability of the energy and luminescence.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7242
       
  • Real-time tracking of cell cycle progression during CD8+ effector and
           memory T-cell differentiation
    • Authors: Ichiko Kinjyo, Jim Qin, Sioh-Yang Tan, Cameron J. Wellard, Paulus Mrass, William Ritchie, Atsushi Doi, Lois L. Cavanagh, Michio Tomura, Asako Sakaue-Sawano, Osami Kanagawa, Atsushi Miyawaki, Philip D. Hodgkin, Wolfgang Weninger
      Abstract: CD8 + memory T cells appear during infection via a process of selection and differentiation that remains poorly understood. Using a fluorescent indicator of cell cycle progression, Kinjyo et al . show that slow-cycling memory precursors are derived from fast-cycling-activated T cells in influenza-infected mice.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7301
       
  • Multimode optomechanical dynamics in a cavity with avoided crossings
    • Authors: D. Lee, M. Underwood, D. Mason, A.B. Shkarin, S.W. Hoch, J.G.E. Harris
      Abstract: Optomechanical systems are typically modelled as a single cavity mode coupled to a mechanical oscillator. Here, the authors report on the realization of a multimode optomechanical setup whose distinct features arise from the mechanically induced coupling between the cavity modes.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7232
       
  • Engineered pairs of distinct photoswitches for optogenetic control of
           cellular proteins
    • Authors: Fuun Kawano, Hideyuki Suzuki, Akihiro Furuya, Moritoshi Sato
      Abstract: Photoreceptor-based photoswitches have proved to be powerful tools for the specific control of protein activity in live cells. Here the authors describe Magnets, a new set of photoswitches based on the Vivid photoreceptor with enhanced hetero-dimerization specificity and variable activation kinetics.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7256
       
  • Pre-B cell receptor binding to galectin-1 modifies galectin-1/carbohydrate
           affinity to modulate specific galectin-1/glycan lattice interactions
    • Authors: Jeremy Bonzi, Olivier Bornet, Stephane Betzi, Brian T. Kasper, Lara K. Mahal, Stephane J. Mancini, Claudine Schiff, Corinne Sebban-Kreuzer, Francoise Guerlesquin, Latifa Elantak
      Abstract: Galectin-1 (GAL1) is a secreted protein that binds to glycans and to the pre-B-cell receptor (pre-BCR). Here Bonzi et al . show that pre-BCR binding to GAL1 causes a conformational change in the GAL1 carbohydrate-binding site to inhibit binding to selected glycans.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7194
       
  • Hippos stem from the longest sequence of terrestrial cetartiodactyl
           evolution in Africa
    • Authors: Fabrice Lihoreau, Jean-Renaud Boisserie, Fredrick Kyalo Manthi, Stéphane Ducrocq
      Abstract: The evolutionary origin of Hippopotamidae, the family of hippos, is poorly understood. Here, the authors describe a new fossil from Kenya that unambiguously roots Hippopotamidae into the group that includes the first large terrestrial mammals to invade Africa, more than 30 million years ago.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7264
       
  • Formation of titanium monoxide (001) single-crystalline thin film induced
           by ion bombardment of titanium dioxide (110)
    • Authors: B.M. Pabón, J.I. Beltrán, G. Sánchez-Santolino, I. Palacio, J. López-Sánchez, J. Rubio-Zuazo, J.M. Rojo, P. Ferrer, A. Mascaraque, M.C. Muñoz, M. Varela, G.R. Castro, O. Rodríguez de la Fuente
      Abstract: Precise surface modification of titanium dioxide is useful for numerous applications. Here, the authors report that high ion dose bombardment transforms the surface of titanium dioxide (110) into single-crystalline titanium oxide (001) thin film, unlike previous lower energy ion bombardment studies.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7147
       
  • Genome-wide association study identifies peanut allergy-specific loci and
           evidence of epigenetic mediation in US children
    • Authors: Xiumei Hong, Ke Hao, Christine Ladd-Acosta, Kasper D. Hansen, Hui-Ju Tsai, Xin Liu, Xin Xu, Timothy A. Thornton, Deanna Caruso, Corinne A. Keet, Yifei Sun, Guoying Wang, Wei Luo, Rajesh Kumar, Ramsay Fuleihan, Anne Marie Singh, Jennifer S. Kim, Rachel E. Story, Ruchi S. Gupta, Peisong Gao, Zhu Chen, Sheila O. Walker, Tami R. Bartell, Terri H. Beaty, M. Daniele Fallin, Robert Schleimer, Patrick G. Holt, Kari Christine Nadeau, Robert A. Wood, Jacqueline A. Pongracic, Daniel E. Weeks, Xiaobin Wang
      Abstract: Food allergy is a growing clinical and public health burden. Here, the authors carry out a genome-wide association study in samples with well-defined allergies to a variety of foods, and identify the 6p21.32 region that significantly increases risk of developing peanut allergy.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7304
       
  • An extreme event of sea-level rise along the Northeast coast of North
           America in 2009–2010
    • Authors: Paul B. Goddard, Jianjun Yin, Stephen M. Griffies, Shaoqing Zhang
      Abstract: Extreme sea level rises are a threat to coastal communities, but their cause, in terms of seasonal or interannual time scales, has received little attention. Here, the authors combine observational and model data to show that one such rise in 2009–10 was caused by a 30% downturn in the Atlantic overturning circulation.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7346
       
  • Activity-driven relaxation of the cortical actomyosin II network
           synchronizes Munc18-1-dependent neurosecretory vesicle docking
    • Authors: Andreas Papadopulos, Guillermo A. Gomez, Sally Martin, Jade Jackson, Rachel S. Gormal, Damien J. Keating, Alpha S. Yap, Frederic A. Meunier
      Abstract: Secretory vesicles must cross a dense cortical actin network to dock and fuse with the plasma membrane. Papadopulos et al . reveal that, in neurosecretory cells, relaxation of this network acts as a 'casting net', driving tethered vesicles towards the plasma membrane.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7297
       
  • Silicon-chip mid-infrared frequency comb generation
    • Authors: Austin G. Griffith, Ryan K.W. Lau, Jaime Cardenas, Yoshitomo Okawachi, Aseema Mohanty, Romy Fain, Yoon Ho Daniel Lee, Mengjie Yu, Christopher T. Phare, Carl B. Poitras, Alexander L. Gaeta, Michal Lipson
      Abstract: Optical frequency combs in the mid-infrared are required for molecular gas detection applications but their realization in compact microresonator-based platforms is challenging. Here, Griffith et al . demonstrate on-chip broadband comb generation on a silicon microresonator spanning from 2.1 to 3.5 μm.
      Citation: Nature Communications
      PubDate: 2015-02-24|2015-02-24
      DOI: 10.1038/ncomms7299
       
  • Visualization and thermodynamic encoding of single-molecule partition
           function projections
    • Authors: Carlos-Andres Palma, Jonas Björk, Florian Klappenberger, Emmanuel Arras, Dirk Kühne, Sven Stafström, Johannes V. Barth
      Abstract: It is challenging to determine thermodynamic quantities for single molecules. Here, the authors access single-molecule thermodynamic information via a microscopic and computational study of a confined molecule, for which the resulting patterns represent a real-space equilibrium probability distribution.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7210
       
  • Cyclic stretching of soft substrates induces spreading and growth
    • Authors: Yidan Cui, Feroz M. Hameed, Bo Yang, Kyunghee Lee, Catherine Qiurong Pan, Sungsu Park, Michael Sheetz
      Abstract: Cells grown on a stiff substrate are stimulated through physical cues to spread, create actin stress fibres and proliferate. Here Cui et al . show that cyclic stretching cells on a soft pillar substrate has the same effect as growth on a stiff substrate, and results in nuclear translocation of YAP and MRTF-A.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7333
       
  • Metabolic cross-feeding via intercellular nanotubes among bacteria
    • Authors: Samay Pande, Shraddha Shitut, Lisa Freund, Martin Westermann, Felix Bertels, Claudia Colesie, Ilka B. Bischofs, Christian Kost
      Abstract: Some bacteria can form nanotubes to transfer proteins and plasmids between neighbouring cells. Here, the authors show that nanotubes can also mediate the exchange of cytoplasmic amino acids between cells of the same or different bacterial species.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7238
       
  • A multicentre-bonded [ZnI]8 cluster with cubic aromaticity
    • Authors: Ping Cui, Han-Shi Hu, Bin Zhao, Jeffery T. Miller, Peng Cheng, Jun Li
      Abstract: Zinc(I) bimetallic clusters have previously been reported, but they are not stable in air. Here, the authors synthesize octametallic Zinc(I) clusters with multi-centred zinc–zinc bonds and extensive electron delocalization over the cluster, resulting in cubic aromaticity and enhanced stability.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7331
       
  • Suppression of nuclear spin bath fluctuations in self-assembled quantum
           dots induced by inhomogeneous strain
    • Authors: E.A. Chekhovich, M. Hopkinson, M.S. Skolnick, A.I. Tartakovskii
      Abstract: Decoherence of the nuclear spin bath causes decoherence of electron spin qubits in the solid state. Here, Chekhovich et al. use spin-echo measurements to demonstrate the suppression of nuclear spin fluctuations in semiconductor quantum dots via strain-induced quadrupolar interactions.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7348
       
  • Self-catalysed aerobic oxidization of organic linker in porous crystal for
           on-demand regulation of sorption behaviours
    • Authors: Pei-Qin Liao, Ai-Xin Zhu, Wei-Xiong Zhang, Jie-Peng Zhang, Xiao-Ming Chen
      Abstract: Controlling and selectively altering the structure of materials opens up the possibility of modulating their physical properties. Here, the authors report a method for altering the properties of a coordination polymer, where the metal centres active molecular oxygen to oxidize the organic ligand.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7350
       
  • A mechanically sensitive cell layer regulates the physical properties of
           the Arabidopsis seed coat
    • Authors: Audrey Creff, Lysiane Brocard, Gwyneth Ingram
      Abstract: Mechanical signalling is an important regulator of plant development. Here, Creff et al. propose that the perception of mechanical signals in growing seeds by a specific cell layer in the seed coat controls the accumulation of gibberellic acid and links mechanical signals to the regulation of seed size.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7382
       
  • Erratum: Interstitial modification of palladium nanoparticles with boron
           atoms as a green catalyst for selective hydrogenation
    • Authors: Chun Wong Aaron Chan, Abdul Hanif Mahadi, Molly Meng-Jung Li, Elena Cristina Corbos, Chiu Tang, Glenn Jones, Winson Chun Hsin Kuo, James Cookson, Christopher Michael Brown, Peter Trenton Bishop, Shik Chi Edman Tsang
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7487
       
  • Volatile signalling by sesquiterpenes from ectomycorrhizal fungi
           reprogrammes root architecture
    • Authors: Franck A. Ditengou, Anna Müller, Maaria Rosenkranz, Judith Felten, Hanna Lasok, Maja Miloradovic van Doorn, Valerie Legué, Klaus Palme, Jörg-Peter Schnitzler, Andrea Polle
      Abstract: Soil-dwelling ectomycorrhizal fungi trigger remodelling of root architecture as part of a mutualistic symbiotic relationship with host plants. Here, Ditengou et al. identify fungal-derived sesquiterpenes as volatile signals capable of stimulating lateral root production in Arabidopsis and Populus .
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7279
       
  • Nutritional stress induces exchange of cell material and energetic
           coupling between bacterial species
    • Authors: Saida Benomar, David Ranava, María Luz Cárdenas, Eric Trably, Yan Rafrafi, Adrien Ducret, Jérôme Hamelin, Elisabeth Lojou, Jean-Philippe Steyer, Marie-Thérèse Giudici-Orticoni
      Abstract: Bacterial communities adapt to changing environments by modulating patterns of nutrient flow between species. Benomar et al . show that under nutrient stress, the sulfate-reducing bacterium Desulfovibrio vulgaris can exchange cytoplasmic material with Clostridium acetobutylicum , altering metabolic flux.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7283
       
  • Direct and selective hydrogenolysis of arenols and aryl methyl ethers
    • Authors: Shuhei Kusumoto, Kyoko Nozaki
      Abstract: Deoxygenating phenols is a difficult task, made more complex by the tendency of hydrogenation techniques to also reduce the aromatic ring. Here, the authors show an iridium catalyst that can selectively cleave the C–O bond in phenols and related compounds, as well as cleaving aryl methyl ethers.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7296
       
  • Refractory dissolved organic nitrogen accumulation in high-elevation lakes
    • Authors: S.J. Goldberg, G.I. Ball, B.C. Allen, S.G. Schladow, A.J. Simpson, H. Masoom, R. Soong, H.D. Graven, L.I. Aluwihare
      Abstract: Some nutrient budgets and fluxes in aquatic environments are poorly constrained. Here, the authors identify a novel pathway of reactive nitrogen sequestration in lakes of the Sierra Nevada, and investigate the relative reactivity of dissolved organic carbon.
      Citation: Nature Communications
      PubDate: 2015-02-23|2015-02-23
      DOI: 10.1038/ncomms7347
       
  • Towards graphyne molecular electronics
    • Authors: Zhihai Li, Manuel Smeu, Arnaud Rives, Valérie Maraval, Remi Chauvin, Mark A. Ratner, Eric Borguet
      Abstract: α-Graphyne, a carbon-expanded version of graphene, is predicted to exhibit high conductivity due to its Dirac cone electronic structure. Here, Li et al. design and synthesize a series of molecular fragments of α-graphyne, on the basis of which single molecular junctions are realized.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7321
       
  • Electroneutrality breakdown and specific ion effects in nanoconfined
           aqueous electrolytes observed by NMR
    • Authors: Zhi-Xiang Luo, Yun-Zhao Xing, Yan-Chun Ling, Alfred Kleinhammes, Yue Wu
      Abstract: It is generally believed that charge neutrality is maintained in electrolytes nanoconfined by uncharged surfaces. Here, the authors show that electroneutrality breakdown is substantial in nanoconfined aqueous electrolytes, and it depends on ion-specific interfacial interactions and ion–ion correlations.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7358
       
  • Consequences of chirality on the dynamics of a water-soluble
           supramolecular polymer
    • Authors: Matthew B. Baker, Lorenzo Albertazzi, Ilja K. Voets, Christianus M.A. Leenders, Anja R.A. Palmans, Giovanni M. Pavan, E.W. Meijer
      Abstract: Water-soluble supramolecular polymers assemble from individual building blocks, but there is a lack of understanding as to how the properties depend on the components. Here the authors show how the introduction of chiral groups can affect the structural features and dynamic behaviour of the polymer.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7234
       
  • Almost quantum correlations
    • Authors: Miguel Navascués, Yelena Guryanova, Matty J. Hoban, Antonio Acín
      Abstract: Physical theories can be classified by the strength of the correlations that they allow to be generated between systems. Here, the authors introduce the set of almost quantum correlations that, despite being larger than strict quantum correlations, do not lead to operational contradictions.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7288
       
  • Roquin binds microRNA-146a and Argonaute2 to regulate microRNA homeostasis
    • Authors: Monika Srivastava, Guowen Duan, Nadia J. Kershaw, Vicki Athanasopoulos, Janet H. C. Yeo, Toyoyuki Ose, Desheng Hu, Simon H. J. Brown, Slobodan Jergic, Hardip R. Patel, Alvin Pratama, Sashika Richards, Anil Verma, E. Yvonne Jones, Vigo Heissmeyer, Thomas Preiss, Nicholas E. Dixon, Mark M. W. Chong, Jeffrey J. Babon, Carola G. Vinuesa
      Abstract: Roquin is an RNA-binding protein that promotes the degradation of specific mRNAs and is crucial for the maintenance of peripheral immune tolerance. Here the authors show that, in addition to its target mRNAs, Roquin can bind miR-146a and the RISC component Ago2 to control homeostasis of both RNA species.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7253
       
  • A highly potent human antibody neutralizes dengue virus serotype 3 by
           binding across three surface proteins
    • Authors: Guntur Fibriansah, Joanne L. Tan, Scott A. Smith, Ruklanthi de Alwis, Thiam-Seng Ng, Victor A. Kostyuchenko, Ramesh S. Jadi, Petra Kukkaro, Aravinda M. de Silva, James E. Crowe, Shee-Mei Lok
      Abstract: There is no licensed vaccine or therapeutic for dengue virus (DENV) infection. Here, the authors show that a highly potent human monoclonal antibody binds to DENV particles in an unusual and very effective way by interacting with three viral envelope proteins.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7341
       
  • Corrigendum: Efficient genome engineering by targeted homologous
           recombination in mouse embryos using transcription activator-like effector
           nucleases
    • Authors: Daniel Sommer, Annika E. Peters, Tristan Wirtz, Maren Mai, Justus Ackermann, Yasser Thabet, Jürgen Schmidt, Heike Weighardt, F. Thomas Wunderlich, Joachim Degen, Joachim L. Schultze, Marc Beyer
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms6927
       
  • High rate and stable cycling of lithium metal anode
    • Authors: Jiangfeng Qian, Wesley A. Henderson, Wu Xu, Priyanka Bhattacharya, Mark Engelhard, Oleg Borodin, Ji-Guang Zhang
      Abstract: Lithium metal is an ideal anode material for rechargeable batteries, but lithium dendritic growth and limited Columbic efficiency prevent its applications. Here, the authors report the use of highly concentrated electrolytes composed of ether solvents and the salt lithium bis(fluorosulfonyl)imide to enable high-rate cycling of lithium anode.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7362
       
  • Enhanced magnetic Purcell effect in room-temperature masers
    • Authors: Jonathan Breeze, Ke-Jie Tan, Benjamin Richards, Juna Sathian, Mark Oxborrow, Neil McN Alford
      Abstract: Masers are promising for applications that use microwave radiation. Here, the authors present a compact room-temperature maser design using a high permittivity dielectric material for the resonator to achieve low optical pumping powers. This design pushes masers closer towards their promised applications.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7215
       
  • An octave-spanning mid-infrared frequency comb generated in a silicon
           nanophotonic wire waveguide
    • Authors: Bart Kuyken, Takuro Ideguchi, Simon Holzner, Ming Yan, Theodor W. Hänsch, Joris Van Campenhout, Peter Verheyen, Stéphane Coen, Francois Leo, Roel Baets, Gunther Roelkens, Nathalie Picqué
      Abstract: Phase-coherent frequency combs in the mid-infrared have important potential applications but their fabrication remains challenging. Here, Kuyken et al . demonstrate an octave-spanning frequency comb in the mid-infrared using a highly nonlinear dispersion-engineered silicon waveguide on a silicon-on-insulator chip.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7310
       
  • Protein kinase D1 drives pancreatic acinar cell reprogramming and
           progression to intraepithelial neoplasia
    • Authors: Geou-Yarh Liou, Heike Döppler, Ursula B. Braun, Richard Panayiotou, Michele Scotti Buzhardt, Derek C. Radisky, Howard C. Crawford, Alan P. Fields, Nicole R. Murray, Q. Jane Wang, Michael Leitges, Peter Storz
      Abstract: Acinar-to-ductal metaplasia (ADM) is a potential early step in the development of pancreatic cancer. Here, using an in vitro model of ADM, the authors show that protein kinase D1 (PKD1) is required for TGFα- or KRAS-induced ADM through Notch activation.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7200
       
  • Developmental enhancers revealed by extensive DNA methylome maps of
           zebrafish early embryos
    • Authors: Hyung Joo Lee, Rebecca F. Lowdon, Brett Maricque, Bo Zhang, Michael Stevens, Daofeng Li, Stephen L. Johnson, Ting Wang
      Abstract: DNA methylation undergoes dynamic changes during development and cell differentiation. Here, by comparing DNA methylomes from different stages of embryonic development of the zebrafish, the authors suggest that developmental enhancers are a major target of DNA methylation changes during embryogenesis.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7315
       
  • Crystalline silicon core fibres from aluminium core preforms
    • Authors: Chong Hou, Xiaoting Jia, Lei Wei, Swee-Ching Tan, Xin Zhao, John D. Joannopoulos, Yoel Fink
      Abstract: The integration of silicon optoelectronic devices in a fibre platform has great potential, but drawing such fibres is difficult. Using a simple, low cost and scalable method, Hou et al . fabricate a metre-long crystalline silicon-core, silica-clad fibre from a preform not containing elemental silicon.
      Citation: Nature Communications
      PubDate: 2015-02-20|2015-02-20
      DOI: 10.1038/ncomms7248
       
  • Integration of Hippo signalling and the unfolded protein response to
           restrain liver overgrowth and tumorigenesis
    • Authors: Hongtan Wu, Luyao Wei, Fuqin Fan, Suyuan Ji, Shihao Zhang, Jing Geng, Lixin Hong, Xin Fan, Qinghua Chen, Jing Tian, Mingting Jiang, Xiufeng Sun, Changnan Jin, Zhen-Yu Yin, Qingxu Liu, Jinjia Zhang, Funiu Qin, Kwang-Huei Lin, Jau-Song Yu, Xianming Deng, Hong-Rui Wang, Bin Zhao, Randy L. Johnson, Lanfen Chen, Dawang Zhou
      Abstract: The Hippo pathway is a major regulator of organ size and growth control. Here Wu et al . provide evidence for a novel link between the Hippo signalling pathway and the unfolded protein response (UPR) in regulating organ growth and tumorigenesis.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7239
       
  • Generation of a ciliary margin-like stem cell niche from self-organizing
           human retinal tissue
    • Authors: Atsushi Kuwahara, Chikafumi Ozone, Tokushige Nakano, Koichi Saito, Mototsugu Eiraku, Yoshiki Sasai
      Abstract: The ciliary margin of the eye functions as a source of multipotent progenitor cells in certain organisms but whether it plays this role in humans has not been easy to study. Here the authors culture human embryonic stem cells that self-organize into retinal tissue, and show that ciliary margin-like growth zones emerge from the developing human retinal tissue and contain stem cell niches.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7286
       
  • Origin of band gaps in graphene on hexagonal boron nitride
    • Authors: Jeil Jung, Ashley M. DaSilva, Allan H. MacDonald, Shaffique Adam
      Abstract: Graphene doesn’t usually have a bandgap but one can appear when the two-dimensional material is placed on a hexagonal boron nitride substrate. Jung et al . now develop a theory that indicates that this occurs because the graphene’s carbon atoms structurally relax when placed on boron nitride.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7308
       
  • Biophysical mechanisms that maintain biodiversity through trade-offs
    • Authors: Justin R. Meyer, Ivana Gudelj, Robert Beardmore
      Abstract: Trade-offs between life history traits are key to understanding biodiversity. Here, the authors use population genetics models and experimental microbial evolution to show that trade-off geometry can be deduced from fundamental biological principles, and used to predict biodiversity stability.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7278
       
  • Unfolding a molecular trefoil derived from a zwitterionic metallopeptide
           to form self-assembled nanostructures
    • Authors: Ye Zhang, Ning Zhou, Junfeng Shi, Susan Sondej Pochapsky, Thomas C. Pochapsky, Bei Zhang, Xixiang Zhang, Bing Xu
      Abstract: Molecular self-assembly can be influenced by a number of external factors, though solvent effects are less commonly explored. Here, the authors present a three-armed metallopeptide complex that has a folded monomeric conformation in organic solvent, but can self-assemble in water into a supramolecular gel.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7165
       
  • A balance between membrane elasticity and polymerization energy sets the
           shape of spherical clathrin coats
    • Authors: Mohammed Saleem, Sandrine Morlot, Annika Hohendahl, John Manzi, Martin Lenz, Aurélien Roux
      Abstract: A relationship between membrane tension and clathrin polymerization during endocytosis has not been experimentally established. Here, the authors show using an in vitro reconstituted system and theoretical modelling that membrane tension regulates clathrin polymerization into spherical cages by varying the membrane budding energy.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7249
       
  • Self-assembled hydrogels utilizing polymer–nanoparticle interactions
    • Authors: Eric A. Appel, Mark W. Tibbitt, Matthew J. Webber, Bradley A. Mattix, Omid Veiseh, Robert Langer
      Abstract: Mouldable hydrogels find a variety of applications in the biomedical industry. Here, Appel et al . show a method to fabricate hydrogels through a self-assembly process based on the interaction between biopolymers and functional nanoparticles for multistage drug delivery in vivo .
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7295
       
  • AAA+ chaperones and acyldepsipeptides activate the ClpP protease via
           conformational control
    • Authors: Malte Gersch, Kirsten Famulla, Maria Dahmen, Christoph Göbl, Imran Malik, Klaus Richter, Vadim S. Korotkov, Peter Sass, Helga Rübsamen-Schaeff, Tobias Madl, Heike Brötz-Oesterhelt, Stephan A. Sieber
      Abstract: Acyldepsipeptides are natural antibiotics that function by activating the ClpP protease and deregulating proteolysis. Here, Gersch et al. show that acyldepsipeptides not only increase access to the active sites but also exert conformational control, thereby allosterically stimulating ClpP catalysis.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7320
       
  • TGF-β3-expressing CD4+CD25−LAG3+ regulatory T cells control
           humoral immune responses
    • Authors: Tomohisa Okamura, Shuji Sumitomo, Kaoru Morita, Yukiko Iwasaki, Mariko Inoue, Shinichiro Nakachi, Toshihiko Komai, Hirofumi Shoda, Jun-ichi Miyazaki, Keishi Fujio, Kazuhiko Yamamoto
      Abstract: B cells reactive against self antigens can cause autoimmune disease, but are normally suppressed by regulatory T cells (Tregs). Here the authors show that a subset of Tregs can suppress lupus in a mouse model by making TGF-β3 cytokine and by engaging an inhibitory PD-1 receptor on B cells.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7329
       
  • Antagonistic interplay between hypocretin and leptin in the lateral
           hypothalamus regulates stress responses
    • Authors: Patricia Bonnavion, Alexander C. Jackson, Matthew E. Carter, Luis de Lecea
      Abstract: The hypothalamic-pituitary-adrenal axis coordinates behavioral and physiological responses to stress but the mechanisms are poorly understood. Here, the authors show that neurons that produce hypocretin/orexin in the lateral hypothalamic area regulate corticosterone release and a variety of behaviors related to the stress response.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7266
       
  • Escape from crossover interference increases with maternal age
    • Authors: Christopher L. Campbell, Nicholas A. Furlotte, Nick Eriksson, David Hinds, Adam Auton
      Abstract: Recombination is a meiotic process that ensures accurate chromosome segregation. Here, the authors characterize recombination patterns in over 4,200 families. Their results show that recombination rate increases with maternal age, and highlight sex differences in the distribution of these events.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7260
       
  • Substrate stress relaxation regulates cell spreading
    • Authors: Ovijit Chaudhuri, Luo Gu, Max Darnell, Darinka Klumpers, Sidi A. Bencherif, James C. Weaver, Nathaniel Huebsch, David J. Mooney
      Abstract: Studies of cellular mechanotransduction commonly use elastic substrates, whereas biological substrates are viscoelastic, exhibiting stress relaxation. Here, the authors show through computational modelling and experiments that viscoelastic substrates can stimulate cell spreading to a greater extent than purely elastic substrates with the same initial stiffness.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7365
       
  • In vivo odourant response properties of migrating adult-born neurons in
           the mouse olfactory bulb
    • Authors: Yury Kovalchuk, Ryota Homma, Yajie Liang, Anatoliy Maslyukov, Marina Hermes, Thomas Thestrup, Oliver Griesbeck, Jovica Ninkovic, Lawrence B. Cohen, Olga Garaschuk
      Abstract: Juxtaglomerular neurons (JGNs) of the mammalian olfactory bulb are generated throughout life, but when and how these adult-born cells acquire responsiveness to sensory stimuli remains unknown. Here, the authors use in vivo two-photon imaging to monitor the migration and integration of adult-born JGNs and their sensory response properties.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7349
       
  • Deltex1 antagonizes HIF-1α and sustains the stability of regulatory T
           cells in vivo
    • Authors: Huey-Wen Hsiao, Tzu-Sheng Hsu, Wen-Hsien Liu, Wan-Chen Hsieh, Ting-Fang Chou, Yu-Jung Wu, Si-Tse Jiang, Ming-Zong Lai
      Abstract: Foxp3, a key transcription factor of regulatory T cells, is targeted to degradation by HIF-1α. Here the authors show that Deltex1 promotes degradation of HIF-1α, thus stabilizing Foxp3 levels and function of regulatory T cells in vivo .
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7353
       
  • TMC-1 attenuates C. elegans development and sexual behaviour in a
           chemically defined food environment
    • Authors: Liusuo Zhang, Daisy G. Gualberto, Xiaoyan Guo, Paola Correa, Changhoon Jee, L. Rene Garcia
      Abstract: The tmc-1 gene encodes for a sodium channel that has been linked to chemosensation in C. elegans . Here the authors show that in a non-optimal nutrient environment, tmc-1 mediates physiological worm responses such as developmental retardation and inhibited sexual behaviour.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7345
       
  • Origin and consequences of silicate glass passivation by surface layers
    • Authors: Stéphane Gin, Patrick Jollivet, Maxime Fournier, Frédéric Angeli, Pierre Frugier, Thibault Charpentier
      Abstract: The long term durability of silicate glasses is of significant importance, not least due to applications in nuclear waste repositories. Here, the authors study glass corrosion and show that its rate drops as a passivating layer forms via a self-healing mechanism.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7360
       
  • Exploring atomic defects in molybdenum disulphide monolayers
    • Authors: Jinhua Hong, Zhixin Hu, Matt Probert, Kun Li, Danhui Lv, Xinan Yang, Lin Gu, Nannan Mao, Qingliang Feng, Liming Xie, Jin Zhang, Dianzhong Wu, Zhiyong Zhang, Chuanhong Jin, Wei Ji, Xixiang Zhang, Jun Yuan, Ze Zhang
      Abstract: Imperfections can greatly alter a material’s properties. Here, the authors investigate the influence of point defects on the electronic structure, charge-carrier mobility and optical absorption of molybdenum disulphide prepared by mechanical exfoliation, physical and chemical vapour deposition.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7293
       
  • Capture Hi-C identifies the chromatin interactome of colorectal cancer
           risk loci
    • Authors: Roland Jäger, Gabriele Migliorini, Marc Henrion, Radhika Kandaswamy, Helen E. Speedy, Andreas Heindl, Nicola Whiffin, Maria J. Carnicer, Laura Broome, Nicola Dryden, Takashi Nagano, Stefan Schoenfelder, Martin Enge, Yinyin Yuan, Jussi Taipale, Peter Fraser, Olivia Fletcher, Richard S. Houlston
      Abstract: Multiple regulatory elements distant from their targets on the linear genome can influence gene expression through chromatin looping. Here, the authors report an improved chromosome conformation capture approach that can be used to identify long-range chromatin interactions in cancer risk loci.
      Citation: Nature Communications
      PubDate: 2015-02-19|2015-02-19
      DOI: 10.1038/ncomms7178
       
  • Dendritic geometry shapes neuronal cAMP signalling to the nucleus
    • Authors: Lu Li, Nicolas Gervasi, Jean-Antoine Girault
      Abstract: Neurons have complex dendritic trees but the rules governing the propagation of signals from dendrites to nuclei remain unclear. Here the authors combine diffusion-reaction modelling and live imaging to investigate the mechanisms regulating cAMP signalling in neurons and find that dendritic tree geometry shapes synapse-to-nucleus signalling.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7319
       
  • RIPK3 promotes cell death and NLRP3 inflammasome activation in the absence
           of MLKL
    • Authors: Kate E. Lawlor, Nufail Khan, Alison Mildenhall, Motti Gerlic, Ben A. Croker, Akshay A. D’Cruz, Cathrine Hall, Sukhdeep Kaur Spall, Holly Anderton, Seth L. Masters, Maryam Rashidi, Ian P. Wicks, Warren S. Alexander, Yasuhiro Mitsuuchi, Christopher A. Benetatos, Stephen M. Condon, W. Wei-Lynn Wong, John Silke, David L. Vaux, James E. Vince
      Abstract: RIPK3 can cause necroptotic cell death via MLKL phosphorylation, and activate NLRP3 inflammasome. Here the authors show that MLKL is dispensable for NLRP3 activation by RIPK3, and highlight how different IAP proteins limit RIPK3 induced apoptosis, necroptosis and IL-1 secretion.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7282
       
  • Dendritic cells induce Th2-mediated airway inflammatory responses to house
           dust mite via DNA-dependent protein kinase
    • Authors: Amarjit Mishra, Alexandra L. Brown, Xianglan Yao, Shutong Yang, Sung-Jun Park, Chengyu Liu, Pradeep K. Dagur, J. Philip McCoy, Karen J. Keeran, Gayle Z. Nugent, Kenneth R. Jeffries, Xuan Qu, Zu-Xi Yu, Stewart J. Levine, Jay H. Chung
      Abstract: House dust mites are a common cause of allergic asthma. Here, the authors show that the Th2-mediated inflammatory responses triggered by mites in mouse airways are mediated by the activation of DNA-dependent protein kinase (DNA-PK) in dendritic cells.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7224
       
  • Hierarchical structural design for fracture resistance in the shell of the
           pteropod Clio pyramidata
    • Authors: Ling Li, James C. Weaver, Christine Ortiz
      Abstract: The hierarchical structural motifs of biomaterials can lead to advantageous mechanical properties. Here, the authors reveal that a fibre-like helical structure across the shell of a planktonic pteropod suppresses crack propagation and is responsible for a high fracture resistance.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7216
       
  • Multiplex CRISPR/Cas9-based genome editing for correction of dystrophin
           mutations that cause Duchenne muscular dystrophy
    • Authors: David G. Ousterout, Ami M. Kabadi, Pratiksha I. Thakore, William H. Majoros, Timothy E. Reddy, Charles A. Gersbach
      Abstract: Duchenne muscular dystrophy is caused by mutations in the dystrophin gene. Here, Ousterout et al . use multiplexed CRISPR/Cas9 genome editing to excise a large portion of the gene that carries over 60% of known dystrophin mutations. They show that this excision restores dystrophin expression in patient-derived cells.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7244
       
  • Defined TLR3-specific adjuvant that induces NK and CTL activation without
           significant cytokine production in vivo
    • Authors: Misako Matsumoto, Megumi Tatematsu, Fumiko Nishikawa, Masahiro Azuma, Noriko Ishii, Akiko Morii-Sakai, Hiroaki Shime, Tsukasa Seya
      Abstract: Activation of TLRs by microbial ligands induces complex innate immune responses to activate host defence. Here the authors show that a synthetic TLR3 ligand can boost protective immunity without robust inflammatory cytokine production, minimizing toxic effects of immunization.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7280
       
  • Hydrodynamic phonon transport in suspended graphene
    • Authors: Sangyeop Lee, David Broido, Keivan Esfarjani, Gang Chen
      Abstract: Hydrodynamic phonon transport occurs when phonons are able to drift over macroscopic distances, leading to the breakdown of Fourier’s law of heat conduction. Here, the authors predict that this regime occurs in suspended graphene at higher temperatures than bulk materials.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7290
       
  • Intermediate DNA methylation is a conserved signature of genome regulation
    • Authors: GiNell Elliott, Chibo Hong, Xiaoyun Xing, Xin Zhou, Daofeng Li, Cristian Coarfa, Robert J.A. Bell, Cecile L. Maire, Keith L. Ligon, Mahvash Sigaroudinia, Philippe Gascard, Thea D. Tlsty, R. Alan Harris, Leonard C. Schalkwyk, Misha Bilenky, Jonathan Mill, Peggy J. Farnham, Manolis Kellis, Marco A. Marra, Aleksandar Milosavljevic, Martin Hirst, Gary D. Stormo, Ting Wang, Joseph F. Costello
      Abstract: Many loci in the mammalian genome are intermediately methylated. Here, by comprehensively identifying these loci and quantifying their relationship with gene activity, the authors show that intermediate methylation is an evolutionarily conserved epigenomic signature of gene regulation.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7363
       
  • A cnidarian homologue of an insect gustatory receptor functions in
           developmental body patterning
    • Authors: Michael Saina, Henriette Busengdal, Chiara Sinigaglia, Libero Petrone, Paola Oliveri, Fabian Rentzsch, Richard Benton
      Abstract: Insect gustatory and olfactory receptor genes encode transmembrane proteins that detect diverse chemicals, but their evolutionary origins are unclear. This study identifies homologues of these genes in non-Bilateria and reveals an unexpected role for one in sea anemone embryonic development.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7243
       
  • NEDD4 controls intestinal stem cell homeostasis by regulating the Hippo
           signalling pathway
    • Authors: Sung Jun Bae, Myungjin Kim, Sung-Hee Kim, Young Eun Kwon, Ji-Hoon Lee, Jaesang Kim, Chin Ha Chung, Won-Jae Lee, Jae Hong Seol
      Abstract: The Hippo pathway plays a role in regulating organ size and stem cell renewal but the regulatory mechanisms that fine-tune this pathway are not well understood. Here the authors report on the role of NEDD4 as a negative regulator of the Hippo signalling components, WW45 and LATS kinase, and in controlling cell proliferation and intestinal stem cell homeostasis.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7314
       
  • Cracking-assisted photolithography for mixed-scale patterning and
           nanofluidic applications
    • Authors: Minseok Kim, Dogyeong Ha, Taesung Kim
      Abstract: Cracks in material are not always unwanted; sometimes, they can be manipulated to produce micro and nanoscale patterns. Here, Kim et al . report a cracking-assisted nanofabrication technique based on conventional photolithography process, which allows accurate control over the geometry of the nanopatterns in arbitrary shape.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7247
       
  • Epigenomic footprints across 111 reference epigenomes reveal
           tissue-specific epigenetic regulation of lincRNAs
    • Authors: Viren Amin, R. Alan Harris, Vitor Onuchic, Andrew R. Jackson, Tim Charnecki, Sameer Paithankar, Sai Lakshmi Subramanian, Kevin Riehle, Cristian Coarfa, Aleksandar Milosavljevic
      Abstract: Tissue-specific functions have been established for some lincRNAs. Here, by analysing 111 reference epigenomes from the NIH Roadmap Epigenomics project, the authors report tissue-specific epigenomic regulation of 3,753 lincRNAs and their strong connection with tissue-specific pathways.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7370
       
  • Epigenetic and transcriptional determinants of the human breast
    • Authors: Philippe Gascard, Misha Bilenky, Mahvash Sigaroudinia, Jianxin Zhao, Luolan Li, Annaick Carles, Allen Delaney, Angela Tam, Baljit Kamoh, Stephanie Cho, Malachi Griffith, Andy Chu, Gordon Robertson, Dorothy Cheung, Irene Li, Alireza Heravi-Moussavi, Michelle Moksa, Matthew Mingay, Angela Hussainkhel, Brad Davis, Raman P. Nagarajan, Chibo Hong, Lorigail Echipare, Henriette O’Geen, Matthew J. Hangauer, Jeffrey B. Cheng, Dana Neel, Donglei Hu, Michael T. McManus, Richard Moore, Andrew Mungall, Yussanne Ma, Patrick Plettner, Elad Ziv, Ting Wang, Peggy J. Farnham, Steven J.M. Jones, Marco A. Marra, Thea D. Tlsty, Joseph F. Costello, Martin Hirst
      Abstract: Epigenetic changes associated with post-natal differentiation have been characterized. Here the authors generate epigenomic and transcriptional profiles from primary human breast cells, providing insights into the transcriptional and epigenetic events that define post-natal cell differentiation in vivo .
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7351
       
  • Experimental diagenesis of organo-mineral structures formed by
           microaerophilic Fe(II)-oxidizing bacteria
    • Authors: Aude Picard, Andreas Kappler, Gregor Schmid, Luca Quaroni, Martin Obst
      Abstract: Twisted iron-rich stalks provide evidence for iron-oxidizing bacteria in sedimentary deposits. Picard et al . show experimentally the persistence of such structures exposed to temperatures and pressures typical of diagenetic conditions, providing spectroscopic signatures to aid their reliable identification.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7277
       
  • Tetrahedrally coordinated carbonates in Earth’s lower mantle
    • Authors: Eglantine Boulard, Ding Pan, Giulia Galli, Zhenxian Liu, Wendy L. Mao
      Abstract: The behaviour of subducted carbonates at high pressures within the Earth is still poorly understood. Here, the authors present experimental and theoretical evidence of a new carbon–oxygen bond in a high-pressure mineral phase, which has implications for the viscosity and mobility of carbonate melts.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7311
       
  • Considerably improved photovoltaic performance of carbon nanotube-based
           solar cells using metal oxide layers
    • Authors: Feijiu Wang, Daichi Kozawa, Yuhei Miyauchi, Kazushi Hiraoka, Shinichiro Mouri, Yutaka Ohno, Kazunari Matsuda
      Abstract: The interface between electrodes and active layers of electronic devices such as solar cells is crucial for the device performance. Here, the authors show that metal oxides MoO x and ZnO play an important role in reducing the electronic barrier at the interface in photovoltaic devices based on carbon nanotubes.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7305
       
  • CEACAM1 induces B-cell survival and is essential for protective antiviral
           antibody production
    • Authors: Vishal Khairnar, Vikas Duhan, Sathish Kumar Maney, Nadine Honke, Namir Shaabani, Aleksandra A. Pandyra, Marc Seifert, Vitaly Pozdeev, Haifeng C. Xu, Piyush Sharma, Fabian Baldin, Florian Marquardsen, Katja Merches, Elisabeth Lang, Carsten Kirschning, Astrid M. Westendorf, Dieter Häussinger, Florian Lang, Ulf Dittmer, Ralf Küppers, Mike Recher, Cornelia Hardt, Inka Scheffrahn, Nicole Beauchemin, Joachim R. Göthert, Bernhard B. Singer, Philipp A. Lang, Karl S. Lang
      Abstract: Antibody responses are regulated by selective survival of B cells with proper antigen specificity. Here the authors show that CEACAM1 is critical for B-cell survival during homeostasis and antiviral responses.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7217
       
  • Small-molecule inhibitors targeting INK4 protein p18INK4C enhance ex vivo
           expansion of haematopoietic stem cells
    • Authors: Yingdai Gao, Peng Yang, Hongmei Shen, Hui Yu, Xianmin Song, Liyan Zhang, Peng Zhang, Haizi Cheng, Zhaojun Xie, Sha Hao, Fang Dong, Shihui Ma, Qing Ji, Patrick Bartlow, Yahui Ding, Lirong Wang, Haibin Liu, Yanxin Li, Hui Cheng, Weimin Miao, Weiping Yuan, Youzhong Yuan, Tao Cheng, Xiang-Qun Xie
      Abstract: The cyclin-dependent kinase inhibitors p18 and p27 confer advantage to the propagation of haematopoietic stem cells (HSCs). In this manuscript, the authors demonstrate that p18 is a potent negative regulator of HSC self-renewal, and identify novel small molecules putatively inhibiting p18 that promote HSC growth in culture and mouse transplant assays.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7328
       
  • Host genetic determinants of microbiota-dependent nutrition revealed by
           genome-wide analysis of Drosophila melanogaster
    • Authors: Adam J. Dobson, John M. Chaston, Peter D. Newell, Leanne Donahue, Sara L. Hermann, David R. Sannino, Stephanie Westmiller, Adam C.-N. Wong, Andrew G. Clark, Brian P. Lazzaro, Angela E. Douglas
      Abstract: The gut microbiota affects animal nutrition, but it is unclear whether this effect depends on host genetic makeup. This study shows that host genotype modifies the gut microbiota’s impact on host nutrition, and identifies genetic determinants of this variation in the fruit fly.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7312
       
  • Unique features of mutations revealed by sequentially reprogrammed induced
           pluripotent stem cells
    • Authors: Shuai Gao, Caihong Zheng, Gang Chang, Wenqiang Liu, Xiaochen Kou, Kun Tan, Li Tao, Kai Xu, Hong Wang, Jun Cai, Jianhui Tian, Shaorong Gao
      Abstract: Mice can be generated from induced pluripotent stem cells (iPSCs) but the impact of accumulated mutations on the developmental potential of the cells remains to be determined. Here the authors show that mice generated from iPSCs tolerate the accumulation of somatic mutations for up to six generations, but their viability decreased with increasing generations.
      PubDate: 2015-02-18|2015-02-18
      DOI: 10.1038/ncomms7318
       
 
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
Fax: +00 44 (0)131 4513327
 
About JournalTOCs
API
Help
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-2014