Authors:ตวงพร กตัญญุตานนท์, ฐานิดา แป้นสมบุญ, จันจิรา จินดามณี, พิลัมภา รุ่งเรือง, มณีรัตน์ เกลี้ยงเกลา, พรนภา หอมจันทร์, ฟิตตรี มอหะ, อิงอร อินทคีรี Pages: 1 - 14 Abstract: The objectives of this cross-sectional descriptive research were to study the level of physical activities and to study the relationship of predisposing, reinforcing, and enabling factors with physical activities of the elderly people in a village, Bang Pla Sub-District, Bang Phli District, SamutPrakan Province. The sample was 200 independent elderly people with least 60 years of age in a village, Bang Pla Sub-District, Bang Phli District, SamutPrakan Province and was selected by using the stratified random sampling based on gender, then simple random sampling was used by a lottery. The questionnaire was used as a research tool for data collection. The obtained data were analyzed using frequency, percentage, mean, standard deviation, chi-square test and Spearman’s rank correlation analysis. The results showed that the elderly people were in a moderate level of physical activities. (=2.96, SD=0.78). The predisposing factor was occupation, which had a correlation with the physical activities of the elderly people at a significance level of 0.05 (p-value = 0.002). Alternatively, gender, age, marital status, educational level, and income level had no significant correlation with the physical activities of the elderly people. Knowledge and attitudes about physical activity were positively correlated with physical activity at low and moderate levels at a significance level of 0.01 (r = 0.379, 0.673 p-value = 0.000). The reinforcing factors consisted of family support, which had a low positive correlation with the physical activities at a significance level of 0.01 (r = 0.068, p-value = 0.000). Similarly, support from the village health volunteers and support from the community had a moderate positive correlation with the physical activities of the elderly people at a significance level of 0.01 (r = 0.643, 0.502, p-value = 0.000). The enabling factor of the elderly people was facility, which had a low positive correlation with the physical activities at a significance level of 0.01 (r = 0.378, p-value = 0.000). PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:ธวัชชัย ทิพย์ทินกร, พัชรพล ฉาบกังวาล, สุธาธิป กิตติธีระกูร Pages: 15 - 31 Abstract: The objective of this research was to study the effect of sodium starch glycolate on dissolution of paracetamol extended release bilayer tablets. The immediate and extended release layers were prepared by wet granulation method. Extended release layer was prepared by using hydroxypropyl methylcellulose K4M (HPMC K4M) as matrix former at 1.25% of extended release layer weight. Sodium starch glycolate was used as disintegrant with concentrations 0, 1, 1.5, 2 and 2.5% of extended release layer weight. In vitro released studies were performed according to dissolution USP 40 and compared with dissolution specification. The results showed that the released rate increased with increased of sodium starch glycolate. The dissolution profile of the drug with 1.5% sodium starch glycolate was similar to that of the innovator. Both were conformed to the acceptance criteria level L1 of USP 40. Dissolution test results were further analysis by comparing with the innovator. The values of difference factor ( ) and similarity factor ( ) were 4 and 68, respectively. Drug released kinetics was followed Fickian diffusion. The mechanism of drug released through the matrix was found to be diffusion swollen and erosion controls. Extended release layer with HPMC K4M 1.25% as matrix former and sodium starch glycolate 1.5% as disintegrant would be benefit for this study. Therefore, the extended released bilayer tablets could be a potential dosage form for delivering paracetamol PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:ปานทิพย์ รัตนศิลป์กัลชาญ, วรภัทร์ บุญเยี่ยม, ธนวัฒน์ กษมาวุฒิ Pages: 47 - 59 Abstract: This study aimed to examine the effect of hemolysis on clinical chemistry analysis. Blood samples were obtained from 30 healthy volunteers in the age range of 20-60 years. Non-hemolyzed plasma was separated from whole blood by centrifugation. Hemolysis was simulated in samples by adding their own hemolysate to their non-hemolyzed plasma to make the final concentration of hemoglobin at 0.9 mg/mL, 1.8 mg/mL, 3.5 mg/mL and 6.7 mg/mL. These samples can be classified as 1+, 2+, 3+ and 4+ hemolysis samples respectively. Subsequently, all samples were analyzed for the following 14 parameters: glucose, BUN, creatinine, uric acid, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, total protein, albumin, total bilirubin, direct bilirubin, AST and ALT using an automatic analyzer. Clinical chemistry analysis showed that different hemolysis levels appear to significantly increase the level of certain tests. Accordingly, hemolysis 1+ affected direct bilirubin level (p<0.05). Hemolysis 2+ affected total bilirubin and AST level (p<0.05). Hemolysis 4+ affected glucose, uric acid, ALT and total protein level (p<0.05). However, hemolysis did not significantly affect to the results of BUN, total cholesterol, triglyceride, HDL-cholesterol, LDL-cholesterol, albumin and creatinine level. In conclusion, these results suggest that different levels of hemolysis may affect different chemical analytic parameters. Considering these results, hemolysis level may be an important factor to prevent unnecessary rejection. PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:ทิพวรรณ เชษฐา, สุรศักดิ์ ตรีนัย Pages: 60 - 76 Abstract: The purpose of this quasi experimental research was to compare total dose of sedative, analgesic used and drug withdrawal symptoms between participants received the nursing intervention base on the Neuman model and the usual nursing care. The research subjects composed of 30 participants as inclusion criteria. We randomly assigned the participants into intervention group and control group. Research instruments used including 1) Experimental instrument was nursing care program base on Neuman model linked to the nursing intervention for preventing and reducing withdrawal symptoms including adminstration of sedative and analgesic drug, promotion of sleep, and comforting touch. 2) Data collecting instrument was Sophia Observation Withdrawal Scale. 3) Monitoring instruments were the nursing activities observation forms including 3.1) Adminstraion of drug for preventing and reducing drug withdrawal symptoms observation form.3.2) Teaching comforting touch to parents and caregivers with demonstraion method observation form 3.3) Promoting sleep observation form. These instruments were tested for content validity by five experts. Total dose of sedative, analgesic used were collected by researcher and drug withdrawal symptoms were collected by research assistants every eight hours. Data was analyzed by descriptive, Mann - whitney U test and repeated measures ANOVA. The findings were as follows:total dose of sedative, analgesic used of critically ill children who received the nursing intervention base on the Neuman model was not different than that critically ill children who received the usual nursing care; and drug withdrawal symptoms of critically ill children who received the nursing intervention base on the Neuman model was significantly less than that of critically ill children received the usual nursing care at the level .05 PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:มนัส รงทอง, อัมรินทร์ คงทวีเลิศ, ดุสิต สุจิรารัตน์, เพชรรัตน์ ภูอนันตานนท์ Pages: 77 - 92 Abstract: The oil palm harvesting activities have always been associated with health, safety and ergonomic problem. Especially ergonomic problem is one of the Musculoskeletal disorders (MSDs), occurred on many causes, such as awkward postures, overloading and repetitive postures. A cross-sectional study was conducted to find the prevalence of MSDs among 270 young oil palm harvesting workers who had an experience of oil palm harvesting at no more than 5 years in Lamae district, Chumphon Province, Thailand. Data were collected by using the modified Nordic questionnaire and face-to-face questionnaire and were analyzed by using descriptive statistics. The study found that prevalence of MSDs in the past 7 days were lower back (61.9%), shoulders or upper arm (30.4%) and hips or thighs (24.4%). In the last 12 months, the study found that prevalence of MSDs was lower back (90.7%), shoulders or upper arm (86.7%) and hips or thighs (76.3%). These finding maybe the health data in promotion, prevention, surveillance, and reduction of hazards from MSDs among young oil palm harvesting workers. PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:อมรรัตน์ ลือนาม, กิตติ ประจันตเสน, นิลาวรรณ งามขำ, วชรดล เส็งลา, ดวงหทัย แสงสว่าง, วิภาวรรณ เพ็งพานิช, กมลทิพย์ รัตนสุวรรณาชัย Pages: 93 - 106 Abstract: The aims of this study were to investigate the prevalence of self-care behavior for prevention of hypertension among population groups of at risk individuals aged over 35 years and its association in the private hospital. This cross-sectional study was conducted during January to May 2018 among 298 participants. A self-administered questionnaire was used to assess factors of self-care behavior for prevention of hypertension. As a predictive analysis, the multiple regression is used to explain the relationship between multiple factors of self-care behavior and prevention of hypertension The result showed that most of the participants (±S.D; 3.22 ±0.21, 95%CI; 3.20-2.24), had a fair level of self-care behavior for prevention of hypertension. The results indicated that the employee status, bachelor’s degree attainment, perception of obstacles, received risk of disease, practical induction, and marital status of widow could be predictive factors of self-care behaviour for prevention of hypertension (Adj R2 =26.82). PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:นงลักษณ์ พรหมติงการ, สุชาติ เครื่องชัย, สุดาวัลย์ สายสืบ, อภิรดี คำเงิน, จุฑาทิพย์ เดชเดชะ Pages: 107 - 119 Abstract: This objective of descriptive research was to study the elderly care in the health service system from the perspectives of elders and families of Lampang, during March to August 2018. The participants were selected by purposive sampling which consisted of 800 elders and families. The instrument was a questionnaire consisting of 2 parts 1) personal data of the sample and 2) views of the elderly and their families on the care of the elderly in the health care service system. The research questionnaire was developed by the researcher who reviewed literature related to the elderly health care service system. The content validity index of questionnaire was 1.00. The data was analyzed using descriptive statistics. The research found that the elderly's perspective on the elderly health care service system was at a high level ( = 3.98, S.D. = 0.67) and the highest was positive attitude to elderly ( = 4.26, S.D. = 0.65). Moreover, the family’s view about the elderly health care service system was at a high level ( = 4.08, S.D. = 0.87) and positive attitude towards elderly was the most popular also ( = 4.33, S.D. = 0.61). The results can help nurses and public health officers by giving a basis for developing a better health care services and quality of nursing. Furthermore, It can be used in public policy and to humanize care that is suitable for the elders and families. PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:สุธาสินี สายวดี, ปีติชา อะมริต, ศลิษา เจริญสุข Pages: 120 - 131 Abstract: The purpose of this study was to analize the treatment of breast cysts in Thailand and to look at alternative ways to treat the condition.Usually breast cysts occur between the age of 35 and 50 years.The incidence is higher in urban than rural areas and affects people who live in economic zones, highly competitive, have higher education, early onset of menstruation, infertility , older age pregnant, lack of breastfeeding and late menopause. This article reviews research studies in China on using Chinese medicine for the treatment of breast cysts. The study provides explanation about the mechanisms and the classification of breast cyst by Traditional Chinese Medicine theory. According to the research in China using Chinese medicine for the treatment of breast cysts is very effective. PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:สิทธิศักดิ์ เครือพิมาย, พรศิริ พันธสี Pages: 132 - 145 Abstract: Human papillomavirus (HPV) is the most common infection in sexually transmitted infections. It is a major cause of many cancers in both female and male organs. The cancers caused by HPV infection in women include cervical cancer , vaginal cancer, cancer of the mouth and throat and anal cancer. In males they include cancer of the penis, cancer of the mouth and throat and anal cancer. Therefore, primary prevention of HPV infection is very important. By avoiding getting HPV, reducing and eliminating the causes or risk factors associated with cancer or enabling the body to resist carcinogens including vaccination against HPV is the primary prevention of effective HPV infection. because it can make a better immunity better than natural HPV infection and is available to both males and females. Nurses have a very important role to play in health promotion and prevention of desease from HPV infection, because of their roles as health assessors, educators, counselors and creators of academic work and systematic knowledge including deep and accurate knowledge about HPV and HPV vaccine to be able to deliver health promotion and disease prevention to the people most effectively. PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:วัชรพงษ์ เรือนคำ, ณรงค์ศักดิ์ หนูสอน Pages: 146 - 160 Abstract: Deaths and injuries from motorcycle accidents are major public health problems in Thailand. Understanding motorcycle accidents is complicated because it has many complicated components. Use of epidemiology perspectives to analyze the situation of motorcycle accidents, the distribution of motorcycle accidents (person, time and place), and the cause of motorcycle accidents in epidemiology triad: human (motorcyclist), agent (motorcycle) and environment (road conditions, environment, and law enforcement). Furthermore, this view will allow us to better understand the problem of motorcycle accidents and to apply the knowledge gained to the prevention and control of motorcycle accidents. Moreover, it will solve the problem effectively and solve the actual causes of the motorcycle accident problem. PubDate: 2019-06-26 Issue No:Vol. 23, No. 1 (2019)
Authors:อุมารัตน์ ศิริจรูญวงศ์ Pages: 161 - 172 Abstract: The Preliminary Hazard Analysis (PHA) technique is a tool used to search for basic hazards and used to search for hazards during the design of production processes or machines in order to set adequate safety measures before production starts. In addition, this technique is very useful for proactive safety management. The PHA technique has a complicated procedure that can use to investigate basic causes of accidents. The implementation of PHA has a total of 6 steps, including analyzing scope determining, the risk level estimation criteria based on relevant factors, hazard analysis team, risk evaluation and eliminating or reducing risk. For the input for hazard identification this consists of data from manuals of concerned machinery, electrical systems, toxicity of chemicals, work instructions and past accident information, etc. The output part consists of issues of various mistakes of process units or machines, danger source and defects or inadequacy of safety measures. Hazardous findings must be registered on the Preliminary Hazard List (PHL) together with the risk level. Risk level should be determined based on the likelihood of occurrence and severity or other factors associated. Hazard identification with this technique leads to the initial system safety requirements (SSRs). However, this technique is only a Preliminary Hazard Analysis. For increasing capabilities, this technique should be used with other techniques such as failure mode effects analysis (FMEA) or what-if. PubDate: 2019-06-27 Issue No:Vol. 23, No. 1 (2019)
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