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  Subjects -> HEALTH AND SAFETY (Total: 1290 journals)
    - CIVIL DEFENSE (18 journals)
    - DRUG ABUSE AND ALCOHOLISM (86 journals)
    - HEALTH AND SAFETY (520 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (378 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (106 journals)
    - PHYSICAL FITNESS AND HYGIENE (101 journals)
    - WOMEN'S HEALTH (81 journals)

HEALTH AND SAFETY (520 journals)                  1 2 3 | Last

Showing 1 - 200 of 203 Journals sorted alphabetically
16 de Abril     Open Access  
A Life in the Day     Hybrid Journal   (Followers: 9)
Acta Informatica Medica     Open Access   (Followers: 1)
Acta Scientiarum. Health Sciences     Open Access  
Adultspan Journal     Hybrid Journal  
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10)
Advances in Public Health     Open Access   (Followers: 20)
African Health Sciences     Open Access   (Followers: 2)
African Journal for Physical, Health Education, Recreation and Dance     Full-text available via subscription   (Followers: 6)
African Journal of Health Professions Education     Open Access   (Followers: 4)
Afrimedic Journal     Open Access   (Followers: 2)
Air Quality, Atmosphere & Health     Hybrid Journal   (Followers: 3)
AJOB Primary Research     Partially Free   (Followers: 3)
American Journal of Family Therapy     Hybrid Journal   (Followers: 11)
American Journal of Health Economics     Full-text available via subscription   (Followers: 11)
American Journal of Health Education     Hybrid Journal   (Followers: 26)
American Journal of Health Promotion     Hybrid Journal   (Followers: 22)
American Journal of Health Studies     Full-text available via subscription   (Followers: 9)
American Journal of Preventive Medicine     Hybrid Journal   (Followers: 21)
American Journal of Public Health     Full-text available via subscription   (Followers: 183)
American Journal of Public Health Research     Open Access   (Followers: 26)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 2)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 2)
Annali dell'Istituto Superiore di Sanità     Open Access  
Annals of Global Health     Open Access   (Followers: 9)
Annals of Health Law     Open Access   (Followers: 3)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15)
Applied Biosafety     Hybrid Journal  
Applied Research In Health And Social Sciences : Interface And Interaction     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Arquivos de Ciências da Saúde     Open Access  
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 8)
Asia Pacific Journal of Health Management     Full-text available via subscription   (Followers: 2)
Asia-Pacific Journal of Public Health     Hybrid Journal   (Followers: 8)
Asian Journal of Gambling Issues and Public Health     Open Access   (Followers: 3)
Association of Schools of Allied Health Professions     Full-text available via subscription   (Followers: 6)
Atención Primaria     Open Access   (Followers: 1)
Australasian Journal of Paramedicine     Open Access   (Followers: 2)
Australian Advanced Aesthetics     Full-text available via subscription   (Followers: 4)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Indigenous HealthBulletin     Free   (Followers: 6)
Autism & Developmental Language Impairments     Open Access   (Followers: 1)
Behavioral Healthcare     Full-text available via subscription   (Followers: 5)
Best Practices in Mental Health     Full-text available via subscription   (Followers: 7)
Bijzijn     Hybrid Journal   (Followers: 2)
Bijzijn XL     Hybrid Journal   (Followers: 1)
Biomedical Safety & Standards     Full-text available via subscription   (Followers: 8)
BLDE University Journal of Health Sciences     Open Access  
BMC Oral Health     Open Access   (Followers: 5)
BMC Pregnancy and Childbirth     Open Access   (Followers: 18)
BMJ Simulation & Technology Enhanced Learning     Full-text available via subscription   (Followers: 7)
Brazilian Journal of Medicine and Human Health     Open Access  
Buletin Penelitian Kesehatan     Open Access   (Followers: 2)
Buletin Penelitian Sistem Kesehatan     Open Access  
Bulletin of the World Health Organization     Open Access   (Followers: 16)
Cadernos de Educação, Saúde e Fisioterapia     Open Access   (Followers: 1)
Cadernos Saúde Coletiva     Open Access   (Followers: 1)
Canadian Family Physician     Partially Free   (Followers: 12)
Canadian Journal of Community Mental Health     Full-text available via subscription   (Followers: 11)
Canadian Journal of Human Sexuality     Hybrid Journal   (Followers: 1)
Canadian Journal of Public Health     Full-text available via subscription   (Followers: 18)
Case Reports in Women's Health     Open Access   (Followers: 2)
Case Studies in Fire Safety     Open Access   (Followers: 12)
Central Asian Journal of Global Health     Open Access   (Followers: 2)
Central European Journal of Public Health     Full-text available via subscription   (Followers: 4)
CES Medicina     Open Access  
Child Abuse Research in South Africa     Full-text available via subscription   (Followers: 1)
Child's Nervous System     Hybrid Journal  
Childhood Obesity and Nutrition     Open Access   (Followers: 11)
Children     Open Access   (Followers: 2)
CHRISMED Journal of Health and Research     Open Access  
Christian Journal for Global Health     Open Access  
Ciência & Saúde Coletiva     Open Access   (Followers: 2)
Ciencia y Cuidado     Open Access  
Ciencia, Tecnología y Salud     Open Access  
ClinicoEconomics and Outcomes Research     Open Access   (Followers: 2)
CME     Hybrid Journal   (Followers: 1)
CoDAS     Open Access  
Community Health     Open Access   (Followers: 1)
Conflict and Health     Open Access   (Followers: 8)
Curare     Open Access  
Current Opinion in Behavioral Sciences     Hybrid Journal   (Followers: 1)
Day Surgery Australia     Full-text available via subscription   (Followers: 2)
Digital Health     Open Access  
Dramatherapy     Hybrid Journal   (Followers: 2)
Drogues, santé et société     Full-text available via subscription  
Duazary     Open Access   (Followers: 1)
Early Childhood Research Quarterly     Hybrid Journal   (Followers: 13)
East African Journal of Public Health     Full-text available via subscription   (Followers: 3)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 16)
EcoHealth     Hybrid Journal   (Followers: 3)
Education for Health     Open Access   (Followers: 4)
electronic Journal of Health Informatics     Open Access   (Followers: 4)
ElectronicHealthcare     Full-text available via subscription   (Followers: 3)
Elsevier Ergonomics Book Series     Full-text available via subscription   (Followers: 5)
Emergency Services SA     Full-text available via subscription   (Followers: 2)
Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde     Open Access  
Environmental Disease     Open Access  
Environmental Sciences Europe     Open Access   (Followers: 1)
Epidemics     Open Access   (Followers: 3)
Epidemiologic Perspectives & Innovations     Open Access   (Followers: 3)
Epidemiology, Biostatistics and Public Health     Open Access   (Followers: 18)
Ethics, Medicine and Public Health     Full-text available via subscription   (Followers: 1)
Ethiopian Journal of Health Development     Open Access   (Followers: 8)
Ethiopian Journal of Health Sciences     Open Access   (Followers: 7)
Ethnicity & Health     Hybrid Journal   (Followers: 13)
European Journal of Investigation in Health, Psychology and Education     Open Access   (Followers: 2)
European Medical, Health and Pharmaceutical Journal     Open Access  
Evaluation & the Health Professions     Hybrid Journal   (Followers: 9)
Evidence-based Medicine & Public Health     Open Access   (Followers: 5)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Expressa Extensão     Open Access  
Face à face     Open Access   (Followers: 1)
Families, Systems, & Health     Full-text available via subscription   (Followers: 8)
Family & Community Health     Partially Free   (Followers: 12)
Family Medicine and Community Health     Open Access   (Followers: 3)
Family Relations     Partially Free   (Followers: 11)
Fatigue : Biomedicine, Health & Behavior     Hybrid Journal   (Followers: 1)
Food and Public Health     Open Access   (Followers: 10)
Frontiers in Public Health     Open Access   (Followers: 7)
Gaceta Sanitaria     Open Access   (Followers: 3)
Galen Medical Journal     Open Access  
Geospatial Health     Open Access  
Gesundheitsökonomie & Qualitätsmanagement     Hybrid Journal   (Followers: 11)
Giornale Italiano di Health Technology Assessment     Full-text available via subscription  
Global Health : Science and Practice     Open Access   (Followers: 5)
Global Health Promotion     Hybrid Journal   (Followers: 15)
Global Journal of Health Science     Open Access   (Followers: 8)
Global Journal of Public Health     Open Access   (Followers: 10)
Global Medical & Health Communication     Open Access  
Globalization and Health     Open Access   (Followers: 5)
Hacia la Promoción de la Salud     Open Access  
Hastings Center Report     Hybrid Journal   (Followers: 3)
HEADline     Hybrid Journal  
Health & Place     Hybrid Journal   (Followers: 15)
Health & Justice     Open Access   (Followers: 5)
Health : An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine     Hybrid Journal   (Followers: 7)
Health and Human Rights     Free   (Followers: 8)
Health and Social Care Chaplaincy     Hybrid Journal   (Followers: 7)
Health and Social Work     Hybrid Journal   (Followers: 48)
Health Behavior and Policy Review     Full-text available via subscription   (Followers: 1)
Health Care Analysis     Hybrid Journal   (Followers: 12)
Health Inform     Full-text available via subscription  
Health Information Management Journal     Hybrid Journal   (Followers: 11)
Health Issues     Full-text available via subscription   (Followers: 1)
Health Policy     Hybrid Journal   (Followers: 33)
Health Policy and Technology     Hybrid Journal   (Followers: 1)
Health Professional Student Journal     Open Access   (Followers: 1)
Health Promotion International     Hybrid Journal   (Followers: 21)
Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals     Full-text available via subscription   (Followers: 10)
Health Promotion Practice     Hybrid Journal   (Followers: 15)
Health Prospect     Open Access   (Followers: 1)
Health Psychology     Full-text available via subscription   (Followers: 46)
Health Psychology Research     Open Access   (Followers: 18)
Health Psychology Review     Hybrid Journal   (Followers: 39)
Health Renaissance     Open Access  
Health Research Policy and Systems     Open Access   (Followers: 10)
Health SA Gesondheid     Open Access   (Followers: 2)
Health Science Reports     Open Access  
Health Sciences and Disease     Open Access   (Followers: 2)
Health Services Insights     Open Access   (Followers: 2)
Health Systems     Hybrid Journal   (Followers: 2)
Health Voices     Full-text available via subscription  
Health, Culture and Society     Open Access   (Followers: 11)
Health, Risk & Society     Hybrid Journal   (Followers: 11)
Healthcare     Open Access   (Followers: 1)
Healthcare in Low-resource Settings     Open Access   (Followers: 1)
Healthcare Quarterly     Full-text available via subscription   (Followers: 8)
HERD : Health Environments Research & Design Journal     Full-text available via subscription  
Highland Medical Research Journal     Full-text available via subscription  
Hispanic Health Care International     Full-text available via subscription  
HIV & AIDS Review     Full-text available via subscription   (Followers: 10)
Home Health Care Services Quarterly     Hybrid Journal   (Followers: 5)
Hong Kong Journal of Social Work, The     Hybrid Journal   (Followers: 2)
Hospitals & Health Networks     Free   (Followers: 3)
IEEE Journal of Translational Engineering in Health and Medicine     Open Access   (Followers: 3)
IMTU Medical Journal     Full-text available via subscription  
Indian Journal of Health Sciences     Open Access   (Followers: 2)
Indonesian Journal for Health Sciences     Open Access   (Followers: 1)
Inmanencia. Revista del Hospital Interzonal General de Agudos (HIGA) Eva Perón     Open Access  
Innovative Journal of Medical and Health Sciences     Open Access  
Institute for Security Studies Papers     Full-text available via subscription   (Followers: 6)
interactive Journal of Medical Research     Open Access  
International Health     Hybrid Journal   (Followers: 5)
International Journal for Equity in Health     Open Access   (Followers: 7)
International Journal for Quality in Health Care     Hybrid Journal   (Followers: 32)
International Journal of Applied Behavioral Sciences     Open Access   (Followers: 2)
International Journal of Behavioural and Healthcare Research     Hybrid Journal   (Followers: 7)
International Journal of Circumpolar Health     Open Access   (Followers: 1)
International Journal of Community Medicine and Public Health     Open Access   (Followers: 5)
International Journal of E-Health and Medical Communications     Full-text available via subscription   (Followers: 2)
International Journal of Environmental Research and Public Health     Open Access   (Followers: 20)
International Journal of Evidence-Based Healthcare     Hybrid Journal   (Followers: 8)
International Journal of Food Safety, Nutrition and Public Health     Hybrid Journal   (Followers: 14)
International Journal of Health & Allied Sciences     Open Access   (Followers: 2)
International Journal of Health Care Quality Assurance     Hybrid Journal   (Followers: 7)
International Journal of Health Geographics     Open Access   (Followers: 6)
International Journal of Health Policy and Management     Open Access   (Followers: 2)
International Journal of Health Professions     Open Access   (Followers: 2)
International Journal of Health Promotion and Education     Hybrid Journal   (Followers: 12)

        1 2 3 | Last

Journal Cover Galen Medical Journal
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2228-5423 - ISSN (Online) 2322-2379
   Published by Shiraz University Homepage  [14 journals]
  • Biodegradable Scaffolds for Cartilage Tissue Engineering

    • Authors: Fatemeh Ahmadi, Rashin Giti, Soliman Mohammadi-Samani, Farhad Mohammadi
      Pages: 70 - 80
      Abstract: Being a connective tissue, the cartilage is present in almost all parts of the body like the rib cage, joints, nose, and ear. Its essential function in body is to serve as a cushion between the joints and prevent the bones friction against each other. In some areas like the rib cage, the cartilage keeps the bones together and creates a shockproof area. Osteoarthritis and traumatic rupture of the cartilage are among the related diseases. Damaged cartilage tissue can be only limitedly repaired because of the low density of chondrocyte and slow metabolism in the tissue. Previous studies achieved different outcomes for the joint-preserving treatment programs such as debridement, mosaicplasty, and perichondrium transplantation; however, the average long-term result is still unsatisfactory. The restriction of clinical success is mainly attributed to the long time required in most treatments for the regeneration of new cartilage at the site of defect. The mechanical conditions of these sites makes the repair process unflavored of the original damaged cartilage. Such problems can be permanently treated by using tissue engineered cartilage. Hence, the limitations can be defeated by using appropriate scaffolds, cell sources, and growth factors. This review dealt with the advances in cartilage tissue engineering, with the focus on cell sources, scaffold materials and growth factors used in cartilage tissue engineering.[GMJ.2017;6(2):70-80]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.696
      Issue No: Vol. 6, No. 2 (2017)
       
  • Fine Particulate Matter (PM2.5) and Health Effects: An Unbridle Problem in
           Iran

    • Authors: Maryam Baghbeheshti, Mohammad Zolfaghari, Regina Rückerl
      Pages: 81 - 94
      Abstract: Particulate matter (PM) is a complex mixture of solid and liquid particles from various sources. Fine PM or PM2.5 is defined as a mass with a size of less than 2.5 μm in aerodynamic diameter and has a large contribution to the world increasing annually. Iran is a developing country set in the Middle East that is not secured from this pollutant mainly due to its industries, desert dust and the travel of dust from the neighboring countries. Poor air quality caused by PM2.5 can induce multiorgan dysfunction including cardiovascular disease, respiratory impairment, and other adverse effects that lead to morbidity and even death. Since PM2.5 is a risk factor for health problems, the comprehension of the detailed molecular mechanisms of PM2.5 including oxidative stress and inflammation would be beneficial. The aim of this review is gathering information from epidemiological studies about the health effects of this pollutant in Iran for the sake of a healthy environment and proposing solutions which can be applied to every country that is concerned about the air quality. [GMJ.2017;6(2):81-94]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.755
      Issue No: Vol. 6, No. 2 (2017)
       
  • Cessation or Continuation of Aspirin in Patients Undergoing 20-gauge Pars
           Plana Vitrectomy due to Diabetic Retinopathy

    • Authors: Reza Ajudani, Mohammad Hossein Khosravi, Mahdi Ramezani-Binabaj, Mohammad Saeid Rezaee-Zavareh, Ali agha Alishiri
      Pages: 95 - 101
      Abstract: Background: This study aimed to evaluate the incidence of ocular hemorrhages in patients with proliferative diabetic retinopathy (PDR) undergoing 20-gauge pars plana vitrectomy (PPV) taking aspirin as an antiplatelet agent versus those who did not take any aspirin. Materials and Methods: A total of 180 patients (mean age of 60.5 ± 9.9 years) with PDR referred to Baqiyatallah University Hospital in 2016 were enrolled in aspirin and control groups each group containing 90 patients. All participants underwent a standard 20-gauge diabetic PPV. Laboratory data, including fasting blood sugar, prothrombin time, partial thromboplastin, bleeding time, and platelets count, and intraoperative data, including bleeding and its type (retinal, subretinal, vitreous, conjunctival, sub-conjunctival, and hyphema), were collected and analyzed using SPSS16 software. Results: Bleeding occurred in 56 patients. There were no significant differences in the incidence of bleeding between aspirin (33 patients) and control groups (23patients) (P= 0.1). Likewise, no significant differences were observed in the type of bleeding between the two groups (P= 0.11). Age, gender, hypertension, type of operation, and laboratory findings were not significant between patients with and without bleeding. Conclusion: The results of this study indicated that taking aspirin is not associated with a higher risk of post-PPV surgery bleeding in comparison with the control group. Additionally, the type of bleeding did not significantly differ between the two groups. Hence, there is no urgent need for discontinuation of this medication in diabetic patients undergoing PPV.[GMJ.2017;6(2):95-101]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.763
      Issue No: Vol. 6, No. 2 (2017)
       
  • Effects of Iranian Traditional Medicine Remedies (Apium Graveolence and
           Trachyspermum Copticum) on Modifying the Quality of Life in Patients with
           Functional Dyspepsia: A Double-Blind Randomized Clinical Trial

    • Authors: Maryam Azimi, Mohammad Javad Zahedi, Mitra Mehrabani, Haleh Tajadini, Farzaneh Zolala, Mohammad Reza Baneshi, Rasool Choopani, Fariba Sharififar, Ali Asadipur, Mehdi Hayatbakhsh, Bijan Ahmadi
      Pages: 102 - 109
      Abstract: Background: Functional dyspepsia (FD) is common digestive diseases affecting patients’ quality of life (QOL). Recently, improving the patients’ QOL is being considered as an important therapeutic objective; several studies have shown that traditional medicine is influential for FD patients improvement. The purpose of the present research was to investigate the effectiveness Iranian traditional medicine remedies on the QOL of patients with FD. Materials and Methods: Through double-blind randomized clinical trial, our research patients were categorized into three groups followed as AT group(Apium graveolence 250 mg and Trachyspermum copticum 250 mg, twice daily), placebo (cornstarch, 500 mg, twice daily), and (omeprazole 20 mg, daily)for a duration of one month and followed up for another one month. The patients’ QOL was measured by Nepean Dyspepsia Index short-version questionnaire at the baseline, 4 and 8 weeks after treatment onset. Results: The patients QOL of AT group after 4 weeks was found to have improved significantly in comparison to those of omeprazole and placebo groups. The statistical difference between omeprazole and placebo groups was not significant. After 8 weeks, the difference between AT and placebo groups remained significant whereas the same was not clear between AT and omeprazole. Conclusion: Regarding our results, AT remedies could prove the FD patients’ QOL more than omeprazole or placebo; therefore, it can be used as an adjuvant therapy for treatment of the disease. [GMJ.2017;6(2):102-109]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.772
      Issue No: Vol. 6, No. 2 (2017)
       
  • Patient Retention in Antiretroviral Therapy Programs; A Retrospective
           Cohort Study in a Triangular HIV Clinic

    • Authors: Azadeh Khalatbari Limaki, Behnam Farhoudi, Mehrnaz Rasoolinejad, Mehrnaz Rasoolinejad, Saeed Safari
      Pages: 110 - 117
      Abstract: Background: High rate of adherence to antiretroviral therapy (ART) is critical for the optimized outcome. The present study aimed to determine the rate of retention in ART programs and its’ associated factors in a triangular clinic. Materials and Methods: The present retrospective cohort study was conducted on people living with HIV receiving care in a triangular clinic affiliated with Iranian research center for HIV/AIDS, Tehran, Iran, from 2003 to 2008. Baseline variables, duration of ART, and cause of treatment discontinuation were gathered using patients’ profile and analyzed by SPSS 21 and STATA 11. Results: Three hundred and seventeen cases with the mean age of 37.69 ± 10.63 (2–76) years were included (83.9% male). Treatment discontinuation had happened in 142 (45.2%) cases. Cause of treatment discontinuation was death in 20 (13.7%) cases and personal preference in 126 (86.3%) individuals. 6, 12, 18, 24, 36, and 60 months retention rates were 81.1%, 58.4%, 48.3%, 35.6%, 22.9%, and 6.3%, respectively. The results of multivariate logistic regression analysis showed a significant association between treatment retention and female sex (OR: 4.10; 95% CI: 1.59–10.56, P=0.003), addiction/drug use (OR: 0.39; 95% CI: 0.21– 0.77, P=0.007), and lamivudine+ zidovudine+ indinavir treatment regimen (OR: 0.63; 95% CI: 0.46 -0.87, P= 0.005). Conclusion: Based on the findings, male sex, addiction/drug use, and type of treatment regimen were among the most important risk factors for ART attrition in HIV-infected patients. [GMJ.2017;6(2):110-117]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.819
      Issue No: Vol. 6, No. 2 (2017)
       
  • Baclofen Reversed the Nicotine-Induced Anxiety-Like Behavior: A Beneficial
           Therapeutic Strategy for Smoking Cessation Aid

    • Authors: Batool Ghorbani yekta, Mobina Kordeforushani, Hoda Aryan
      Pages: 118 - 127
      Abstract: Background: Nicotine dependence is the most widespread form of substance abuse. Anxiety is one of the prominent symptoms in withdrawal syndromes of nicotine. Nucleus Accumbens (NAc) is a principle area which participates in several behavioral responses (e.g., anxiety), and several studies reported that receptors are involved in the modulation of anxiety. This study was aimed to examine the interaction of baclofen and nicotine on anxiety behavior in NAc shell. Materials and Methods: Rats weighing between 220 and 250g were used. The guide cannulas were implanted bilaterally into the shell of the NAc. Nicotine (0.025, 0.05 and 0.5 μg/rat) and baclofen (0.25, 0.5 and 2 μg/rat) and the co-administration of nicotine (0.025, 0.05 and 0.5μg/rat) with baclofen (0.25 μg/rat) were microinjected through the infusion cannula. The elevated plus-maze (EPM) was used to evaluate the anxiety-like parameters, and all data were recorded and analyzed. Results: Intra-NAc administration of nicotine (0.5μg/rat) decreased anxiety (P<0.001). Microinjections of baclofen (0.5 and 2 μg/rat) decreased anxiety (P< 0.001). However, there were no significant changes in anxiety-like parameters at the lowest dose of baclofen (0.25μg/rat). Co-administration of an ineffective dose of baclofen (0.25 μg/rat) with 3 doses of nicotine (0.025, 0.05 and 0.5 μg/rat) reversed the effects of nicotine in an effective dose (0.5μg/rat). Conclusion: Our result indicated that GABAergic agonist baclofen in ineffective doses could reverse the effects of nicotine on anxiety symptoms. Furthermore, our result suggested that enhancement of GABA transmission through activation of GABA-B receptors on NAc shell could reverse nicotine anxiety-related effects. It may be a strategy of treatment for smoking cessation aid.[GMJ.2017;6(2):118-27]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.825
      Issue No: Vol. 6, No. 2 (2017)
       
  • Job Satisfaction and Stress Levels of Nurses Working in Oncology Wards; A
           Multicenter Study

    • Authors: Soheila Zareifar, Sezaneh Haghpanah, Zahra Beigipour, Samaneh Hosseini, Mohammad Ali Molavi, Majid Naderi
      Pages: 128 - 135
      Abstract: Background: Oncology nurses work in a stressful environment. Subsequently, stress cause job dissatisfaction and mental exhaustion. The aim of our study was to determine the most important factors that affect satisfaction and stress levels among the nurses in the oncology ward. Materials and Methods: This descriptive cross-sectional study has been performed on 156 working nurses of three Iranian Universities of Medical Sciences (Hormozgan, Zahedan, and Shiraz) during a period of 3 months from January to March in 2015. The values of satisfaction and stress levels were assessed by a modified translated version of McCloskey/Mueller Satisfaction Scale questionnaire. Results: The highest percentage of dissatisfaction (unsatisfied and very unsatisfied) was respectively in the field of income (87.8%), occupational safety in nursing profession (78.2%), work environment and facilities (75.6%) and the relation between nursing and personal life (72.4%). The main areas of stress (very high and high) respectively wherein the field of impact of stress on personal life (84%), communication with patients (83.3%), stressful environment (82.7%) and using safe equipment in the workplace (74.4%). Conclusion: Based on our results, the most common issues related to stress and dissatisfaction of nurses of oncology ward were determined as financial issues, occupational safety, stressful environment, and the impact of their work on the personal life. Managers and healthcare providers should be noticed in this regard and take into account these important issues by implementing appropriate interventions. Considering stress-reduction program, regular visits by psychologists and more vacation can also help to relieve their stress. [GMJ.2017;6(2):128-35]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.722
      Issue No: Vol. 6, No. 2 (2017)
       
  • Preparation and Characterization of Myristoylated Chitosan Nanogel as
           Carrier of Silibinin for Breast Cancer Therapy

    • Authors: Maliheh Entezari, Fereshteh Atabi
      Pages: 136 - 144
      Abstract: Background: Biopolymer has been known to have compatibility; nontoxic nature and degradation behavior. Chitosan (CS) is being widely used in various biomedical and pharmaceutical applications and serves as a drug carrier. Nanotechnology has emerged as tumor cell target therapy and increase drug bioavailability. One of the most common and important models of cancer in women is breast cancer, which is the fifth most common death reason. Silibinin (SIL) as a flavonolignan, has demonstrated anticancer effects against various human cancer cells, such as breast cancer. Materials and Methods: Myristoylated CS (MCS) nanoparticles were prepared on the base of 9:1 ratio related to CS: Myristate and loaded with SIL, for the first time. Then in vitro loading and releasing capacity of nano drug were evaluated. The nanogel structure and its derivatives were characterized by different biophysical methods. The MCF-7 breast cancer cell line and human umbilical vein endothelial cells (HUVEC) cell lines were incubated with 100, 150, and 200μg/ml of SIL and nanoSIL. Afterward cell cytotoxicity was measured by MTT assay. Lethal dose 50 (LD50) or IC50 was measured by Pharm software. Results: Compared to HUVEC as normal cells, the proliferation of MCF-7 cells were significantly inhibited (P<0.01) by SIL and nano-SIL in a concentration-related manner in defining times (P<0.05). SIL-loaded nanogels were more effective than SIL alone (P<0.01). The mean size of MCS particles was about 20nm. The MCS nanogels were spheral and homogen with a dense surface. The loading efficiency was obtained about 85-95%. Conclusions: It seems the obtained MCS nanogel can play a real and important role as a suitable drug carrier with a high loading capacity to treat cancerous cells with the least side effect. [GMJ.2017;6(2):136-44]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.822
      Issue No: Vol. 6, No. 2 (2017)
       
  • Generation and Maintenance of Neural Progenitor Cell Lines Derived from
           Human Embryonic Stem Cells by Small Molecules

    • Authors: Shiva Nemati, Ebrahim Shahbazi, Reza Hajihosseini
      Pages: 145 - 156
      Abstract: Background: A new research perspective for human neurodevelopment and neurological disease modeling involves the use of human embryonic stem cells (hESC). The development of robust protocols that yield adequate neural cell populations with definite regional identities were the prerequisites for these comparative studies. Materials and Methods: We used small molecules cocktail to generate two neural progenitor cell (NPC) lines from hESCs as following: the first experimental group included Noggin, Dorsomorphin, CHIR99021 and A83-01(NDCA) and the second group composed of Noggin, Dorsomorphin, CHIR99021 and SIS3 (NDCS). To validate our findings, we expanded both cell lines for over 20 passages in vitro and checked for chromosomal stability, as well as expressions of neural and regional identity markers by immunofluorescence staining. Gene expression analysis was quantified by RT-PCR at different passages up to passage 20. Results: Both cell lines proliferated in an adherent culture system in the presence of FGF2. They retained progenitor characteristics of NESTIN, SOX1, and PAX6 protein expression, formed rosette-like structures, and had the high neurogenic capacity. Importantly, the NPC populations in their first 10 passages expressed rostral markers (OTX2 and TH), and the next 10 passages (10-20) changed their specification toward the hindbrain where they expressed HOXA3and HOXB2, which correlated with a normal central nervous system development pattern. Conclusion: These NPCs offer a new system to study human central nervous system development and disease modeling of specific neurodegenerative diseases. [GMJ.2017;6(2):143-56]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.764
      Issue No: Vol. 6, No. 2 (2017)
       
  • Successful Treatment of Chronic Scalp Seborrheic Dermatitis Using
           Traditional Persian Medicine: A Case Report and Literature Review

    • Authors: Mohammad Mahdi Parvizi, Mojtaba Heydari, Mohammad Reza Namazi
      Pages: 157 - 159
      Abstract: Background: Seborrheic Dermatitis (SD) is a common, chronic and relapsing disorder caused by changes in the cutaneous microflora. This disease is called hozaz in traditional Persian medicine (TPM). Topical application of Althaea officinalis L. in combination with vinegar has been traditionally recommended for treatment of this disease. Case Report: This paper presents long-term remission of resistant SD in a 32-year-old female patient with topical application of A. officinalis in combination with vinegar, as well as the TPM’s healthy lifestyle advice and dietary recommendations. Conclusion: This remarkable clinical experience suggests that further research should be conducted on the effect of A. officinalis and TPM’s recommendations in the treatment of SD. [GMJ.2017;6(2):157-59]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.706
      Issue No: Vol. 6, No. 2 (2017)
       
  • Role of Optic Nerve Fenestration as an Effective Salvage Therapy in
           Cerebral Venous Thrombosis: A Case Report and Review of Literature

    • Authors: Abolfazl Rahimi, Kourosh Karimi Yarandi, Hoda Aryan
      Pages: 160 - 165
      Abstract: Background: Cerebral venous thrombosis (CVT) is an uncommon, unrecognized type of stroke mostly affecting young people. Although a headache is the most common clinical manifestation of CVT, neurological focal signs like diplopia and papilledema are also frequently reported in the patients with such a problem. Currently, specific treatment for CVT involves anticoagulation or thrombolytic therapy. Case Report: In this report, we described a 13-year-old female, who was referred to our clinic with a headache and progressive loss of vision due to increased intracranial pressure. Along with usual anticoagulant therapy, we performed the optic nerve sheath fenestration (ONSF) to improve her vision. The patient visual acuity was improved, and after 11 months’ follow-up, no complication was detected. Conclusion: The ONSF can be safe and beneficial in patients with CVT and who are in immediate danger of visual deterioration despite being treated by other means. [GMJ.2017;6(2):160-65]
      PubDate: 2017-06-25
      DOI: 10.22086/gmj.v6i2.883
      Issue No: Vol. 6, No. 2 (2017)
       
 
 
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