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  Subjects -> HEALTH AND SAFETY (Total: 1296 journals)
    - CIVIL DEFENSE (18 journals)
    - DRUG ABUSE AND ALCOHOLISM (87 journals)
    - HEALTH AND SAFETY (526 journals)
    - HEALTH FACILITIES AND ADMINISTRATION (377 journals)
    - OCCUPATIONAL HEALTH AND SAFETY (105 journals)
    - PHYSICAL FITNESS AND HYGIENE (101 journals)
    - WOMEN'S HEALTH (82 journals)

HEALTH AND SAFETY (526 journals)                  1 2 3 | Last

Showing 1 - 200 of 203 Journals sorted alphabetically
16 de Abril     Open Access  
A Life in the Day     Hybrid Journal   (Followers: 9)
Acta Informatica Medica     Open Access   (Followers: 1)
Acta Scientiarum. Health Sciences     Open Access  
Adultspan Journal     Hybrid Journal  
Advances in Child Development and Behavior     Full-text available via subscription   (Followers: 10)
Advances in Public Health     Open Access   (Followers: 23)
African Health Sciences     Open Access   (Followers: 2)
African Journal for Physical, Health Education, Recreation and Dance     Full-text available via subscription   (Followers: 6)
African Journal of Health Professions Education     Open Access   (Followers: 6)
Afrimedic Journal     Open Access   (Followers: 2)
Air Quality, Atmosphere & Health     Hybrid Journal   (Followers: 4)
AJOB Primary Research     Partially Free   (Followers: 3)
American Journal of Family Therapy     Hybrid Journal   (Followers: 11)
American Journal of Health Economics     Full-text available via subscription   (Followers: 13)
American Journal of Health Education     Hybrid Journal   (Followers: 30)
American Journal of Health Promotion     Hybrid Journal   (Followers: 24)
American Journal of Health Sciences     Open Access   (Followers: 6)
American Journal of Health Studies     Full-text available via subscription   (Followers: 10)
American Journal of Preventive Medicine     Hybrid Journal   (Followers: 25)
American Journal of Public Health     Full-text available via subscription   (Followers: 202)
American Journal of Public Health Research     Open Access   (Followers: 29)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 2)
Analytic Methods in Accident Research     Hybrid Journal   (Followers: 4)
Annals of Global Health     Open Access   (Followers: 9)
Annals of Health Law     Open Access   (Followers: 3)
Annals of Tropical Medicine and Public Health     Open Access   (Followers: 15)
Applied Biosafety     Hybrid Journal  
Applied Research In Health And Social Sciences : Interface And Interaction     Open Access   (Followers: 2)
Archive of Community Health     Open Access  
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Arquivos de Ciências da Saúde     Open Access  
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 8)
Asia Pacific Journal of Health Management     Full-text available via subscription   (Followers: 3)
Asia-Pacific Journal of Public Health     Hybrid Journal   (Followers: 8)
Asian Journal of Gambling Issues and Public Health     Open Access   (Followers: 3)
Association of Schools of Allied Health Professions     Full-text available via subscription   (Followers: 6)
Atención Primaria     Open Access   (Followers: 1)
Australasian Journal of Paramedicine     Open Access   (Followers: 2)
Australian Advanced Aesthetics     Full-text available via subscription   (Followers: 4)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Indigenous HealthBulletin     Free   (Followers: 6)
Autism & Developmental Language Impairments     Open Access   (Followers: 5)
Behavioral Healthcare     Full-text available via subscription   (Followers: 6)
Best Practices in Mental Health     Full-text available via subscription   (Followers: 8)
Bijzijn     Hybrid Journal   (Followers: 2)
Bijzijn XL     Hybrid Journal   (Followers: 1)
Biomedical Safety & Standards     Full-text available via subscription   (Followers: 8)
BLDE University Journal of Health Sciences     Open Access  
BMC Oral Health     Open Access   (Followers: 5)
BMC Pregnancy and Childbirth     Open Access   (Followers: 20)
BMJ Simulation & Technology Enhanced Learning     Full-text available via subscription   (Followers: 7)
Brazilian Journal of Medicine and Human Health     Open Access  
Buletin Penelitian Kesehatan     Open Access   (Followers: 2)
Buletin Penelitian Sistem Kesehatan     Open Access  
Bulletin of the World Health Organization     Open Access   (Followers: 17)
Cadernos de Educação, Saúde e Fisioterapia     Open Access   (Followers: 1)
Cadernos Saúde Coletiva     Open Access   (Followers: 1)
Canadian Family Physician     Partially Free   (Followers: 12)
Canadian Journal of Community Mental Health     Full-text available via subscription   (Followers: 12)
Canadian Journal of Human Sexuality     Hybrid Journal   (Followers: 1)
Canadian Journal of Public Health     Full-text available via subscription   (Followers: 20)
Case Reports in Women's Health     Open Access   (Followers: 3)
Case Studies in Fire Safety     Open Access   (Followers: 12)
Central Asian Journal of Global Health     Open Access   (Followers: 2)
Central European Journal of Public Health     Full-text available via subscription   (Followers: 4)
CES Medicina     Open Access  
Child Abuse Research in South Africa     Full-text available via subscription   (Followers: 1)
Child's Nervous System     Hybrid Journal  
Childhood Obesity and Nutrition     Open Access   (Followers: 10)
Children     Open Access   (Followers: 2)
CHRISMED Journal of Health and Research     Open Access  
Christian Journal for Global Health     Open Access  
Ciência & Saúde Coletiva     Open Access   (Followers: 2)
Ciencia y Cuidado     Open Access  
Ciencia, Tecnología y Salud     Open Access  
ClinicoEconomics and Outcomes Research     Open Access   (Followers: 2)
CME     Hybrid Journal   (Followers: 1)
CoDAS     Open Access  
Community Health     Open Access   (Followers: 2)
Conflict and Health     Open Access   (Followers: 8)
Contraception and Reproductive Medicine     Open Access  
Curare     Open Access  
Current Opinion in Behavioral Sciences     Hybrid Journal   (Followers: 3)
Day Surgery Australia     Full-text available via subscription   (Followers: 2)
Digital Health     Open Access   (Followers: 1)
Dramatherapy     Hybrid Journal   (Followers: 2)
Drogues, santé et société     Full-text available via subscription  
Duazary     Open Access   (Followers: 1)
Early Childhood Research Quarterly     Hybrid Journal   (Followers: 15)
East African Journal of Public Health     Full-text available via subscription   (Followers: 3)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 16)
EcoHealth     Hybrid Journal   (Followers: 4)
Education for Health     Open Access   (Followers: 5)
electronic Journal of Health Informatics     Open Access   (Followers: 6)
ElectronicHealthcare     Full-text available via subscription   (Followers: 4)
Elsevier Ergonomics Book Series     Full-text available via subscription   (Followers: 5)
Emergency Services SA     Full-text available via subscription   (Followers: 2)
Ensaios e Ciência: Ciências Biológicas, Agrárias e da Saúde     Open Access  
Environmental Disease     Open Access   (Followers: 2)
Environmental Sciences Europe     Open Access   (Followers: 2)
Epidemics     Open Access   (Followers: 4)
Epidemiologic Perspectives & Innovations     Open Access   (Followers: 5)
Epidemiology, Biostatistics and Public Health     Open Access   (Followers: 20)
Ethics, Medicine and Public Health     Full-text available via subscription   (Followers: 2)
Ethiopian Journal of Health Development     Open Access   (Followers: 8)
Ethiopian Journal of Health Sciences     Open Access   (Followers: 7)
Ethnicity & Health     Hybrid Journal   (Followers: 13)
European Journal of Investigation in Health, Psychology and Education     Open Access   (Followers: 2)
European Medical, Health and Pharmaceutical Journal     Open Access  
Evaluation & the Health Professions     Hybrid Journal   (Followers: 10)
Evidence-based Medicine & Public Health     Open Access   (Followers: 6)
Evidência - Ciência e Biotecnologia - Interdisciplinar     Open Access  
Expressa Extensão     Open Access  
Face à face     Open Access   (Followers: 1)
Families, Systems, & Health     Full-text available via subscription   (Followers: 8)
Family & Community Health     Partially Free   (Followers: 12)
Family Medicine and Community Health     Open Access   (Followers: 6)
Family Relations     Partially Free   (Followers: 11)
Fatigue : Biomedicine, Health & Behavior     Hybrid Journal   (Followers: 1)
Food and Public Health     Open Access   (Followers: 11)
Frontiers in Public Health     Open Access   (Followers: 7)
Gaceta Sanitaria     Open Access   (Followers: 3)
Galen Medical Journal     Open Access  
Geospatial Health     Open Access  
Gesundheitsökonomie & Qualitätsmanagement     Hybrid Journal   (Followers: 9)
Giornale Italiano di Health Technology Assessment     Full-text available via subscription  
Global Health : Science and Practice     Open Access   (Followers: 5)
Global Health Promotion     Hybrid Journal   (Followers: 16)
Global Journal of Health Science     Open Access   (Followers: 9)
Global Journal of Public Health     Open Access   (Followers: 12)
Global Medical & Health Communication     Open Access   (Followers: 1)
Globalization and Health     Open Access   (Followers: 5)
Hacia la Promoción de la Salud     Open Access  
Hastings Center Report     Hybrid Journal   (Followers: 3)
HEADline     Hybrid Journal  
Health & Place     Hybrid Journal   (Followers: 15)
Health & Justice     Open Access   (Followers: 5)
Health : An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine     Hybrid Journal   (Followers: 7)
Health and Human Rights     Free   (Followers: 8)
Health and Social Care Chaplaincy     Hybrid Journal   (Followers: 7)
Health and Social Work     Hybrid Journal   (Followers: 51)
Health Behavior and Policy Review     Full-text available via subscription   (Followers: 1)
Health Care Analysis     Hybrid Journal   (Followers: 14)
Health Inform     Full-text available via subscription  
Health Information Management Journal     Hybrid Journal   (Followers: 15)
Health Issues     Full-text available via subscription   (Followers: 2)
Health Notions     Open Access  
Health Policy     Hybrid Journal   (Followers: 36)
Health Policy and Technology     Hybrid Journal   (Followers: 1)
Health Professional Student Journal     Open Access   (Followers: 1)
Health Promotion International     Hybrid Journal   (Followers: 21)
Health Promotion Journal of Australia : Official Journal of Australian Association of Health Promotion Professionals     Full-text available via subscription   (Followers: 10)
Health Promotion Practice     Hybrid Journal   (Followers: 15)
Health Prospect     Open Access   (Followers: 1)
Health Psychology     Full-text available via subscription   (Followers: 48)
Health Psychology Research     Open Access   (Followers: 18)
Health Psychology Review     Hybrid Journal   (Followers: 40)
Health Renaissance     Open Access  
Health Research Policy and Systems     Open Access   (Followers: 12)
Health SA Gesondheid     Open Access   (Followers: 2)
Health Science Reports     Open Access  
Health Sciences and Disease     Open Access   (Followers: 2)
Health Services Insights     Open Access   (Followers: 2)
Health Systems     Hybrid Journal   (Followers: 3)
Health Voices     Full-text available via subscription  
Health, Culture and Society     Open Access   (Followers: 13)
Health, Risk & Society     Hybrid Journal   (Followers: 12)
Healthcare     Open Access   (Followers: 1)
Healthcare in Low-resource Settings     Open Access   (Followers: 1)
Healthcare Quarterly     Full-text available via subscription   (Followers: 8)
Healthy-Mu Journal     Open Access  
HERD : Health Environments Research & Design Journal     Full-text available via subscription  
Highland Medical Research Journal     Full-text available via subscription  
Hispanic Health Care International     Full-text available via subscription  
HIV & AIDS Review     Full-text available via subscription   (Followers: 11)
Home Health Care Services Quarterly     Hybrid Journal   (Followers: 6)
Hong Kong Journal of Social Work, The     Hybrid Journal   (Followers: 2)
Hospitals & Health Networks     Free   (Followers: 4)
IEEE Journal of Translational Engineering in Health and Medicine     Open Access   (Followers: 3)
IMTU Medical Journal     Full-text available via subscription  
Indian Journal of Health Sciences     Open Access   (Followers: 2)
Indonesian Journal for Health Sciences     Open Access   (Followers: 1)
Inmanencia. Revista del Hospital Interzonal General de Agudos (HIGA) Eva Perón     Open Access  
Innovative Journal of Medical and Health Sciences     Open Access  
Institute for Security Studies Papers     Full-text available via subscription   (Followers: 5)
interactive Journal of Medical Research     Open Access  
International Health     Hybrid Journal   (Followers: 5)
International Journal for Equity in Health     Open Access   (Followers: 7)
International Journal for Quality in Health Care     Hybrid Journal   (Followers: 34)
International Journal of Applied Behavioral Sciences     Open Access   (Followers: 2)
International Journal of Behavioural and Healthcare Research     Hybrid Journal   (Followers: 8)
International Journal of Circumpolar Health     Open Access   (Followers: 1)
International Journal of Community Medicine and Public Health     Open Access   (Followers: 5)
International Journal of E-Health and Medical Communications     Full-text available via subscription   (Followers: 2)
International Journal of Environmental Research and Public Health     Open Access   (Followers: 20)
International Journal of Evidence-Based Healthcare     Hybrid Journal   (Followers: 8)
International Journal of Food Safety, Nutrition and Public Health     Hybrid Journal   (Followers: 16)
International Journal of Health & Allied Sciences     Open Access   (Followers: 3)
International Journal of Health Care Quality Assurance     Hybrid Journal   (Followers: 10)

        1 2 3 | Last

Journal Cover CES Medicina
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   ISSN (Print) 0120-8705 - ISSN (Online) 2215-9177
   Published by SciELO Homepage  [711 journals]
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  • 17-hydroxyprogesterone levels in blood from the heels of healthy full-term
           newborns

    • Abstract: Background and aim: Congenital adrenal hyperplasia is caused by enzymatic abnormalities in the synthesis of adrenal steroids. A pilot study was carried out to measure the values of 17- hydroxyprogesterone (17-OHP) in a sample of healthy full-term newborns; the present study aims to determine if birth weight or gender have differences on 17-OHP. Design: Transversal, descriptive, and prolective study. Methods: We included 81 healthy full-term newborns with normal prenatal controls born between July 18th, 2014, and August 1st, 2015. We took whole blood from heel pricks when the babies were three to five days old. Socioeconomic and clinical data were collected. Non-extracted 17-OHP ELISA was used. Its cut-off point was 20 ng/ml. If results were above cut-off point, babies were recalled for a new measure since transient high 17-hydroxyprogesterone levels are possible until babies are three months of age. Results: Gestational age varied between 37.0 to 41.5 weeks. Non-extracted 17-OHP levels ranged between 2.6 to 29.5 ng/mL (median: 11.5, IQR 7.2 to 15.1). 17-OHP levels variation per birth weight or gender were not found. Conclusions: Expected lesser variation in term newborns may explain these results. Quality issues should be solved before starting a screening program in our population because socioeconomic issues cause most problems in recalling positive screening babies.Resumen Justificación: la hiperplasia adrenal congénita es una enfermedad autosómica recesiva ocasionada por anormalidades enzimáticas en la síntesis de los esteroides adrenales. Se realizó un estudio para medir los valores de 17- hidroxiprogesterona en una muestra de neonatos a término sanos. El objetivo fue conocer si existían diferencias en el valor de 17-OHP según edad gestacional y sexo. Diseño: estudio transversal, descriptivo y prolectivo. Métodos: se incluyeron 81 neonatos con controles prenatales normales y nacidos entre julio 18 de 2014 y agosto 1 de 2015. Se obtuvieron muestras de sangre del talón cuando los bebés tenían entre tres a cinco días de vida. Se recolectaron datos socioeconómicos y clínicos. Se utilizó un ELISA de 17-OHP no extraída. El punto de corte de la prueba de ELISA de 17-OHP fue 20 ng/mL. Si los resultados estaban por encima del valor de corte, se citaron los bebés para una nueva medición, dado que es posible hallar una hiper 17-hidroxiprogesteronemia hasta los tres meses de edad. Resultados: la edad gestacional varió entre 37 a 41,2 semanas. Los valores de 17-OHP no extraída variaron entre 2,6 a 29,5 ng/mL (mediana 11,5 y RIQ 7,2 - 15,1). Los niveles de 17-OHP no variaron según peso al nacer o sexo. Conclusión: estos resultados se podrían explicar por una menor variación esperada en neonatos a término. Se deben resolver algunos problemas de calidad antes de poder empezar un programa de tamizaje en nuestra población, debido a que causas socioeconómicas generaron dificultad al reevaluar los niños con resultados positivos de tamizaje.
       
  • Prevalence of preoperative anemia in elective cardiovascular surgery and
           association with blood transfusions in a health institution in Pereira

    • Abstract: Resumen Introducción: La anemia preoperatoria en cirugía cardiovascular viene en incremento a nivel global. Tiene una fuerte asociación con la realización de transfusiones sanguíneas e incremento de la morbimortalidad. En Colombia no se encuentran estudios que evidencien esta problemática a pesar de la importancia que tiene en el pronóstico y desenlace postoperatorio. Objetivo: Determinar la prevalencia de anemia previa a cirugía cardiovascular programada, la cantidad de transfusiones sanguíneas postoperatorias de concentrado globular realizadas y su asociación con la anemia, en la Institución Prestadora de Salud (IPS) Clínica San Rafael de Pereira durante junio de 2015 a junio de 2016. Método: Estudio descriptivo de corte transversal analítico con 129 pacientes sometidos a cirugía cardiovascular programada. El análisis de datos se realizó mediante Microsoft Excel 2013 y el software Stata 14. Resultados: Se obtuvo una prevalencia de anemia previa a cirugía cardiovascular programada de 39,5 %. En el grupo de pacientes anémicos fueron transfundidos el 58,8 %. Se encontró asociación entre la anemia y la realización de transfusiones sanguíneas (IC 95 %: 0,17-0,82). Conclusiones: Estos resultados deben llevar a la implementación de estrategias para el adecuado manejo de la anemia preoperatoria en estos pacientes. Introduction: Preoperative anemia in cardiovascular surgery is increasing globally. It has a strong association with blood transfusion and increased morbidity and mortality. In Colombia, there are no studies that show this problem despite the importance of prognosis and postoperative outcome. Objective: To determine the prevalence of anemia prior to scheduled cardiovascular surgery, the number of postoperative blood transfusions of globular concentrate performed and its association with anemia at the “Institución Prestadora de Salud (IPS) Clínica San Rafael” of Pereira between June 2015 and June 2016. Method: Cross-sectional descriptive study. A population of 129 patients undergoing scheduled cardiovascular surgery was selected. Data analysis was performed using Microsoft Excel 2013 and Stata 14 software. Results: A prevalence of anemia prior to scheduled cardiovascular surgery was obtained of 39.5 %. Among the anemic patients, 58.8 % of the patients were transfused. An association was found between anemia and blood transfusion CI: 95 %: 0.17-0.82. Conclusion: These results must carry out the implementation of strategies for the proper management of preoperative anemia in these patients.
       
  • Probabilistic evaluation of arrhythmic cardiac dynamics with and without
           metoprolol

    • Abstract: Resumen Introducción: A partir de la teoría de los sistemas dinámicos y de la teoría de la probabilidad se han desarrollado metodologías altamente sensibles de aplicación clínica que permiten diferenciar normalidad, enfermedad y evolución hacia la enfermedad cardiaca. Métodos: Se seleccionaron los registros Holter de siete casos normales y 73 con diagnóstico de arritmia con y sin tratamiento terapéutico de metoprolol. Se aplicaron medidas de probabilidad establecidas previamente para evaluar la frecuencia cardiaca máxima, mínima y promedio, así como el número de latidos por hora. Resultados: Casi la mitad de los casos con arritmias y sin tratamiento presentaron medidas matemáticas de enfermedad y de evolución hacia la enfermedad, mientras que en el grupo con tratamiento con metoprolol, tres cuartas partes cumplieron con estas características. Conclusiones: Se lograron distinciones matemáticas más objetivas entre dinámicas cardiacas tratadas con y sin metoprolol, las cuales pueden ser de gran utilidad para realizar seguimiento individual. Introduction: Based on the theory of dynamic systems and probability theory, highly sensitive clinical methodologies have been developed to differentiate normality, disease and evolution towards cardiac disease. Methods: Holter recordings, 7 normal and 73 with arrhythmia diagnosis with and without therapeutic treatment of Metoprolol, were selected. Probability measures, established in a previous work, were applied for assessing maximum, minimal and average heart rate and beats per hour. Results: It was found that almost a half of the cases with arrhythmias without beta-blocker therapy exhibited mathematical measures of illness and evolution towards disease, whereas in the treatment group with Metoprolol, three quarters accomplished these features. Conclusions: More objective mathematical distinctions were achieved between cardiac dynamics treated with and without metoprolol, which is very useful for individual follow-up.
       
  • Role of Notch signaling pathway in the differentiation of immune cells

    • Abstract: Resumen La vía de señalización Notch es una vía conservada evolutivamente y está involucrada en el control de diversos eventos durante el desarrollo de las células eucariotas. Esta vía se ha relacionado con la expresión y la diferenciación de las células inmunes; por lo tanto, su activación es fundamental en la expresión de la respuesta inmune innata y adquirida, que permite a los mamíferos defenderse frente antígenos externos. The Notch signaling pathway is evolutionarily preserved and is involved in the control of several events during the development of eukaryotic cells. This pathway has been linked to expression and differentiation of immune cells, therefore it´s activation is critical in the expression of the innate immune and acquired response that allows mammals to defend themselves against external antigens.
       
  • Evolution of coronary drug-eluting stents, from the first to the fourth
           generation

    • Abstract: Resumen Las enfermedades cardiovasculares son la principal causa de muerte a nivel mundial y dentro de éstas se encuentra la enfermedad obstructiva de las arterias coronarias. El tratamiento más común para dicha enfermedad es la angioplastia con stent, que busca recuperar la luz de la arteria y revascularizar al paciente. Desde la aprobación del primer stent metálico la cardiología intervencionista ha experimentado un desarrollo continuo, impulsado por la necesidad de tener alternativas de tratamiento más seguras y eficaces. Dichos avances se reflejan en cuatro generaciones de stents liberadores de fármacos. El presente artículo busca describir las principales características de cada una de estas generaciones. Cardiovascular disease is the leading cause of death worldwide and within these the coronary artery disease. The most common treatment for this condition is angioplasty with stent, which seeks to recover the lumen of the artery and revascularization the patient. Since the adoption of the first bare metal stent the area of interventional cardiology has experienced continuous development driven by the need for a safe and effective alternative treatment. These advances are reflecting in four generations of drug-eluting stents. This article aims to describe the main features of each of these generations.
       
  • Agenesis of the corpus callosum: A little-known topic

    • Abstract: Resumen El cuerpo calloso está presente sólo en mamíferos placentarios y se compone de aproximadamente 200 a 800 millones de axones que conectan ambos hemisferios cerebrales. La disgenesia del cuerpo calloso puede ser completa (agenesia del cuerpo calloso) o parcial (hipoplasia del cuerpo). La agenesia del cuerpo calloso es una malformación que puede ocurrir de forma aislada o en asociación con otras alteraciones sistémicas o del sistema nervioso central y es una de las malformaciones más frecuentes en el cerebro, con una prevalencia estimada de 1 en 4 000 nacidos vivos. Entre los hallazgos clínicos más frecuentes se encuentran retraso mental, problemas visuales y convulsiones. El diagnóstico prenatal puede realizarse mediante ecografía y resonancia magnética a partir de la semana 20 de gestación. El diagnóstico posnatal puede hacerse mediante ecografía, tomografía computarizada y resonancia magnética. Actualmente, no existe un tratamiento específico, aunque se ha propuesto iniciar un programa de estimulación precoz y de ser posible un programa de rehabilitación psicomotriz que ofrezca mejoría de los trastornos motores y del aprendizaje. Es posible la realización de cirugía cuando existen malformaciones asociadas que sean potencialmente corregidas y, si existen convulsiones, deben manejarse farmacológicamente. Corpus callosum is present only in placental mammals and is composed by approximately 200 - 800 million axons that connect left and right hemispheres. Dysgenesis of corpus callosum may be complete, known as agenesis of the corpus callosum, or partial, known as hypoplasia of the Corpus. Agenesis of the corpus callosum is a malformation that may occur in an isolated way or in association with other disorders of central nervous system. It is one of the most frequent malformations in cerebrum with an estimated prevalence of 1/ 4000 000 births. Among the most frequent clinical findings in patients with agenesis of the Corpus Callosum are mental retardation, visual impairment and seizures. Prenatal diagnosis may be performed through ultrasound and magnetic resonance from week 20 of pregnancy. Postnatal diagnosis may be carried out by performing ultrasound, computerized tomography or magnetic resonance. Currently, there is no specific treatment for ACC. An early stimulation program has been proposed and, if possible, a psychomotor rehabilitation program that offers improvement of motor and learning disorders. Surgical choice is contemplated only for management of associated malformations susceptible of being corrected; symptomatic treatment must be carried out when there are convulsive syndromes.
       
  • The patient safety culture: approaches and methodologies for measurement

    • Abstract: Resumen Introducción: El concepto de cultura de la seguridad del paciente se desarrolla en las denominadas “organizaciones de alta confiabilidad”, como estrategia para enfrentar la problemática de los eventos adversos. Objetivo: Revisar los enfoques que han predominado en cultura de la seguridad del paciente y describir algunas herramientas que se han utilizado para su medición. Metodología: Revisión narrativa enfocada en la conceptualización de cultura de la seguridad. Resultados: El término cultura de la seguridad es utilizado por la literatura con varios significados. La polisemia del término y en particular la confusión con la noción de “clima de seguridad”, implica también confusiones en los métodos e interpretación de las mediciones. Se identifican dos enfoques conceptuales básicos en el estudio de la cultura de la seguridad: el antropológico y el funcionalista, siendo este último el predominante en el desarrollo de instrumentos utilizados para su medición; estos últimos, sin embargo, presentan constructos y propiedades métricas variables. Conclusión: El estudio de la seguridad del paciente, como categoría en desarrollo, debería utilizar los enfoques de medición disponibles con una mirada crítica, integrando técnicas de entrevista y estudios cualitativos, en especial de tipo etnográfico, que suministren información más integral y útil en la toma de decisiones encaminadas a mejorar la seguridad y confiabilidad de la atención médica. : Introduction: The notion of Patient Safety Culture has been developed strongly linked to the concept of “High Reliability Organizations”, as a strategy to face the problem of adverse events. Objective: To review the approaches that have prevailed in Patient Safety Culture and describe some tools that have been used for its measurement. Methodology: Narrative review focused on the conceptualization of safety culture. Results: Technical literature uses the term safety culture with several meanings. The multiple meanings of the term, and particularly the vagueness with the term “safety climate” also involve confusions in the methods and interpretations of measurements. Two main conceptual approaches to the study of the safety culture were identified: the anthropological and the functionalist approaches, the latter being predominant in the development of instruments used to measure Patient Safety Culture, however, their constructs and their metric properties are widely heterogeneous. Conclusion: The study of patient safety as developing category, one should use the available measurement approaches with a critical view, integrating information from other sources such as interviews and qualitative studies, including ethnographic approach, to provide more comprehensive and useful tools in the decision-making process aimed at improving the safety and reliability of medical care.
       
  • Acute hemorrhagic childhood edema

    • Abstract: Resumen El edema agudo hemorrágico de la infancia es una vasculitis leucocito-clástica aguda que afecta a niños hasta los dos años y está caracterizado por la aparición de lesiones purpúricas tipo pápulas y placas en forma de diana, edema en miembros inferiores y fiebre de bajo grado. Se trata de un cuadro benigno y autolimitado, por lo cual su manejo es sintomático. El objetivo de este trabajo es describir un caso de edema agudo hemorrágico y discutir su presentación con la literatura actual. Presentamos un caso clínico de una niña de dos años quien es llevada a la consulta por un cuadro de edema y lesiones equimóticas en maléolos, asociado a síntomas respiratorios de dos meses de evolución. Posteriormente, aparecieron lesiones cutáneas, purpúricas, simétricas, de predominio en miembros inferiores, tipo rosetas, sobreelevados y confluyentes, asociadas a prurito y lesiones similares en brazos, sin compromiso del estado general. Los exámenes de laboratorio mostraron una velocidad de sedimentación glomerular y proteína C reactiva elevadas e IgM positiva para Mycoplasma, así como vas-culitis leucocitoclástica en una biopsia de piel. Se realizó tratamiento para el cuadro respiratorio y el prurito. El cuadro remitió en forma espontánea sin recurrencias posteriores. El diagnóstico correcto del edema agudo hemorrágico de la infancia es fundamental para disminuir el subdiagnóstico, evitar gastos médicos y antibioticoterapia innecesaria. Acute hemorrhagic edema of infancy is an acute leukocytoclastic vasculi-tis, that affects children up to 2 years old, characterized by the appearance of purpura papules and plaques in the form of a bulls-eye, lower limb edema and low-grade fever; It is a benign and self-limiting disease so its management is symptomatic. The aim of this report is to describe a case acute hemorrhagic edema of infancy and to discuss their presentation with the current scientific literature. We report the clinical case of a 2 years-old girl, who consulted for edema and ecchymotic lesions on the malleolus, with a 2-month history of respiratory symptoms associated. Thereafter, coalesced and symmetrical purpuric skin lesions predominantly in lower limbs, rosettes type and raised associated with itching and similar injuries in arms, without effecting general wellbeing. Laboratory tests showed an elevated sedimentation rate and C-reactive protein, IgM positive for Mycoplasma, and leukocytoclastic vasculitis in the skin biopsy. Differential diagnoses were discarded. Treatment for respiratory symptoms and pruritus was performed. The clinical manifestation disappeared spontaneously without further recurrences. The correct diagnosis of the disease is essential to reduce sub-diagnosis, avoiding unnecessary medical expenses and antibiotic therapy.
       
  • Gnathostomiasis an increasingly common disease in Colombia

    • Abstract: Resumen La tríada clásica de viaje al Sudeste asiático u a otras áreas endémicas donde se consumen mariscos crudos o mal cocidos, acompañado de paniculitis y eosinofilia periférica, debe alertar al médico sobre una entidad conocida como gnatostomiasis, una infección parasitaria causada por la tercera larva del nemátodo Gnathostoma spp, que generalmente se ve en zonas tropicales y subtropicales. Afecta principalmente la piel, y de allí, puede migrar a tejidos profundos, llegando a comprometer órganos como pulmón, ojos, oídos, tracto gastrointestinal y genitourinario, y menos frecuente el sistema nervioso central. Se presenta el caso de un paciente con cuadro de tres días de evolución consistente en edema, eritema, calor, prurito y dolor en región pectoral izquierda, con la posterior formación de vesícula sobre la lesión inicial y un trayecto lineal eritematoso e indurado sobre la tetilla izquierda; luego del consumo de langostinos en la costa colombiana. Con el antecedente epidemiológico, los hallazgos clínicos e histológicos se hizo el diagnóstico de gnatostomiasis y se realizó manejo exitoso con albendazol. The classic triad travel to Southeast Asia or to other endemic areas where raw or undercooked seafood, panniculitis and peripheral eosinophilia are consumed, should alert the physician to an entity known as gnathostomiasis, a parasitic infection caused by the third larva of the nematode Gnathostoma spp, usually seen in tropical and subtropical areas. It mainly affects the skin, and from there, you can migrate to deeper tissues, reaching compromise organs like lungs, eyes, ears, gastrointestinal and genitourinary tracts, and less frequent central nervous system. For a patient with three-day box consisting in high swelling, redness, warmth, itching and pain in the left pectoral region, with the subsequent formation of vesicle on the initial injury linear path and an erythematous indurated occurs on the teat left; after consumption of shrimp on the Colombian coast. With the epidemiological history, clinical and histological findings were diagnosed as gnathostomiasis, management began with albendazole presenting picture resolution.
       
  • Ischemic stroke related to acute consumption of cocaine

    • Abstract: Cocaine is one of the most common used psychomotor stimulants in the world. It's often used during the second and third decade of life. Nowadays, cocaine abuse in Colombia is rising, with negative effects for the consumer's health and making it a problem of public health. Cardiovascular diseases are the most common side effects related to cocaine abuse. However, adverse neurological effects remain to be a very important cause of morbidity and mortality. Particularly, the risk of ischemic stroke might be up to seven-fold higher in cocaine users in comparison to non-users. In the following report, we describe the case of a 22-year-old man who presented to the emergency department with a hemispheric ischemic stroke secondary to cocaine intake. Next, we review the key toxicological aspects and the physiopathology of this neurological complication, with special emphasis in the effect of the toxic metabolite "norcocaine", which can explain most of the adverse neurological outcomes. Finally, we review the therapeutic options for cocaine induced ischemic stroke.Resumen La cocaína es una de las sustancias sicomotoras más usadas en el mundo. Es comúnmente utilizada durante la segunda y tercera década de la vida. Actualmente, el abuso de cocaína en Colombia está en aumento, con efectos negativos para la salud del consumidor, además de estar convirtiéndose en un grave problema de salud pública. Los efectos adversos más comunes del abuso de cocaína son los efectos cardiovasculares. Sin embargo, los efectos adversos neurológicos continúan siendo una importante causa de morbilidad y mortalidad. Particularmente, el riesgo de ataque cerebro vascular isquémico podría aumentarse siete veces más en pacientes consumidores de cocaína comparado con pacientes no consumidores. En el siguiente reporte de caso, describimos el caso de un paciente de 22 años, quien ingresó al servicio de urgencias con un ataque cerebro vascular isquémico secundario al uso de cocaína. Posteriormente, discutimos los principales aspectos toxicológicos y la fisiopatología de esta complicación neurológica, con énfasis especial en los efectos tóxicos del metabolito activo norcocaína, el cual pudiera explicar la mayoría de los efectos cardiovasculares adversos. Finalmente, planteamos el enfoque terapéutico del ataque cerebro vascular isquémico secundario a cocaína.
       
  • Mesenteric cystic lymphangioma of small bowel mimicking ovarian tumor

    • Abstract: Resumen El linfangioma quístico, caracterizado por proliferación de los espacios linfáticos, es una lesión infrecuente en pacientes adultos. Menos del 1% de todos los linfangiomas corresponden a linfangiomas del intestino delgado. La presentación clínica es diversa, variando desde un quiste abdominal asintomático, diagnosticado de forma incidental, a un cuadro de abdomen agudo. Se presenta un caso de linfangioma mesentérico quístico del intestino delgado en una mujer de 30 años y quien consultó por dolor abdominal y vómitos. La ecografía y la tomografía computada abdominal mostraron un quiste con múltiples septos en el cuadrante inferior derecho simulando un tumor de ovario. En la laparotomía se encontró un tumor quístico, lobulado y marrón, procedente del mesenterio del intestino delgado. A la paciente se le realizó resección de la tumoración y del intestino delgado adyacente con reconstrucción del tránsito intestinal. La evaluación histológica confirmó el diagnóstico de linfangioma mesentérico quístico. Cystic lymphangioma, characterized by proliferation of lymphatic spaces, is an infrequent lesion in adult patients. Less than 1% of all lymphangiomas correspond to small-bowel lymphangiomas. Clinical presentation can be diverse ranging from incidental abdominal cysts to an acute abdomen. We report a case of small bowel mesenteric cystic lymphangioma in a 30 years-old woman who presented with abdominal pain and vomiting. The abdominal ultrasound and computed tomography scan showed a cystic multiseptated mass at the right lower quadrant mimicking an ovarian tumor. Laparotomy found a lobulated, brown, cystic tumor from the small bowel mesentery. The patient underwent resection of the tumor and the adjacent small intestine with reconstruction of the intestinal transit. The histological study confirmed diagnosis of mesenteric cystic lymphangioma.
       
 
 
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