Subjects -> MEDICAL SCIENCES (Total: 8690 journals)
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PATHOLOGY (100 journals)

Showing 1 - 100 of 100 Journals sorted alphabetically
Academic Pathology     Open Access   (Followers: 5)
Acta Neuropathologica Communications     Open Access   (Followers: 1)
Advances in Anatomic Pathology     Hybrid Journal   (Followers: 22)
Advances in Molecular Pathology     Hybrid Journal   (Followers: 1)
Advances in Plant Pathology     Full-text available via subscription   (Followers: 6)
American Journal of Clinical Pathology     Full-text available via subscription   (Followers: 33)
American Journal of Dermatopathology     Hybrid Journal   (Followers: 18)
American Journal of Forensic Medicine and Pathology     Hybrid Journal   (Followers: 30)
American Journal of Pathology     Hybrid Journal   (Followers: 33)
American Journal of Surgical Pathology     Hybrid Journal   (Followers: 39)
Analytical Cellular Pathology     Open Access   (Followers: 3)
Annals of Cytology and Pathology     Open Access   (Followers: 3)
Annals of Diagnostic Pathology     Hybrid Journal   (Followers: 15)
Annals of Oral & Maxillofacial Surgery     Open Access   (Followers: 7)
Annals of Tropical Pathology     Open Access  
Annual Review of Pathology Mechanisms of Disease     Full-text available via subscription   (Followers: 7)
Archives of Pathology & Laboratory Medicine     Full-text available via subscription   (Followers: 31)
Assessment and Treatment of Child Psychopathology and Developmental Disabilities     Full-text available via subscription   (Followers: 4)
Basic and Applied Pathology     Open Access   (Followers: 3)
BMC Clinical Pathology     Open Access   (Followers: 7)
Brain Pathology     Hybrid Journal   (Followers: 5)
Brain Tumor Pathology     Hybrid Journal   (Followers: 6)
Bulletin de la Société de pathologie exotique     Hybrid Journal   (Followers: 1)
Cancer Cytopathology     Partially Free   (Followers: 24)
Cardiovascular Pathology     Hybrid Journal   (Followers: 4)
Case Reports in Clinical Pathology     Open Access   (Followers: 1)
Case Reports in Pathology     Open Access   (Followers: 7)
Clinical Neuropathology     Full-text available via subscription   (Followers: 1)
Clinical Pathology     Open Access   (Followers: 3)
Comparative Clinical Pathology     Hybrid Journal   (Followers: 3)
Critical Values     Full-text available via subscription  
Cytopathology     Hybrid Journal   (Followers: 14)
Der Pathologe     Hybrid Journal   (Followers: 2)
Dermatopathology     Open Access   (Followers: 3)
Diagnostic Cytopathology     Hybrid Journal   (Followers: 15)
Diagnostic Histopathology     Full-text available via subscription   (Followers: 14)
Diagnostic Pathology     Open Access   (Followers: 13)
Egyptian Journal of Pathology     Partially Free   (Followers: 1)
Endocrine Pathology     Hybrid Journal   (Followers: 4)
Experimental and Molecular Pathology     Hybrid Journal   (Followers: 5)
Experimental and Toxicologic Pathology     Hybrid Journal   (Followers: 10)
Fetal and Pediatric Pathology     Hybrid Journal   (Followers: 4)
Folia Neuropathologica     Open Access  
Forensic Science, Medicine, and Pathology     Hybrid Journal   (Followers: 34)
Frontiers in Pathology and Genetics     Open Access   (Followers: 3)
Head and Neck Pathology     Hybrid Journal   (Followers: 7)
Hepatoma Research     Open Access   (Followers: 2)
Histopathology     Hybrid Journal   (Followers: 30)
Human Pathology     Hybrid Journal   (Followers: 30)
Indian Journal of Pathology and Microbiology     Open Access   (Followers: 4)
Inflammation and Cell Signaling     Open Access   (Followers: 3)
International Journal of Clinical and Experimental Pathology     Open Access   (Followers: 2)
International Journal of Experimental Pathology     Hybrid Journal   (Followers: 1)
International Journal of Gynecological Pathology     Hybrid Journal   (Followers: 9)
International Journal of Ophthalmic Pathology     Hybrid Journal   (Followers: 3)
International Journal of Oral & Maxillofacial Pathology     Open Access   (Followers: 9)
International Journal of Surgical Pathology     Hybrid Journal   (Followers: 9)
Iranian Journal of Pathology     Open Access  
Journal of Clinical & Experimental Pathology     Open Access   (Followers: 3)
Journal of Clinical Pathology     Hybrid Journal   (Followers: 13)
Journal of Clinical Pathology and Forensic Medicine     Open Access   (Followers: 9)
Journal of Comorbidity     Open Access  
Journal of Comparative Pathology     Hybrid Journal   (Followers: 5)
Journal of Cutaneous Pathology     Hybrid Journal   (Followers: 11)
Journal of Depression and Anxiety     Open Access   (Followers: 2)
Journal of Diagnostic Pathology     Open Access   (Followers: 9)
Journal of Hematopathology     Hybrid Journal   (Followers: 5)
Journal of Morphological Sciences     Open Access  
Journal of Neuropathology & Experimental Neurology     Hybrid Journal   (Followers: 1)
Journal of Oral and Maxillofacial Pathology     Open Access   (Followers: 3)
Journal of Oral Pathology & Medicine     Hybrid Journal   (Followers: 5)
Journal of Pathology     Hybrid Journal   (Followers: 13)
Journal of Pathology : Clinical Research     Open Access   (Followers: 1)
Journal of Pathology Informatics     Open Access   (Followers: 2)
Journal of Pathology of Nepal     Open Access   (Followers: 1)
Journal of Physiology and Pathophysiology     Open Access   (Followers: 1)
Modern Pathology     Hybrid Journal   (Followers: 32)
Molecular and Cellular Biomedical Sciences     Open Access   (Followers: 3)
Molecular Diagnosis & Therapy     Hybrid Journal   (Followers: 3)
Neuropathology     Hybrid Journal   (Followers: 1)
Neuropathology and Applied Neurobiology     Hybrid Journal  
Ocular Oncology and Pathology     Full-text available via subscription  
Open Journal of Bacteriology     Open Access   (Followers: 2)
Open Journal of Pathology     Open Access   (Followers: 3)
Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology     Full-text available via subscription   (Followers: 9)
Pathogenesis     Open Access  
Pathology     Hybrid Journal   (Followers: 12)
Pathology & Oncology Research     Hybrid Journal   (Followers: 5)
Pathology - Research and Practice     Hybrid Journal   (Followers: 4)
Pathology and Laboratory Medicine International     Open Access   (Followers: 7)
Pathology International     Hybrid Journal   (Followers: 2)
Pathology Research International     Open Access   (Followers: 1)
Pediatric and Developmental Pathology     Hybrid Journal   (Followers: 5)
Revista de Patologia do Tocantins     Open Access  
Revista de Senología y Patología Mamaria     Full-text available via subscription  
Seminars in Diagnostic Pathology     Hybrid Journal   (Followers: 10)
Seminars in Immunopathology     Hybrid Journal   (Followers: 3)
Surgical Pathology Clinics     Full-text available via subscription   (Followers: 9)
Ultrastructural Pathology     Hybrid Journal   (Followers: 1)
Патологія     Open Access  
Similar Journals
Journal Cover
Pathogenesis
Journal Prestige (SJR): 0.129
Citation Impact (citeScore): 1
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2214-6636
Published by Elsevier Homepage  [3200 journals]
  • Multiple sclerosis is prominent in the Gulf states: Review

    • Authors: Eiman M.A. Mohammed
      Pages: 19 - 38
      Abstract: Publication date: May 2016
      Source:Pathogenesis, Volume 3, Issue 2
      Author(s): Eiman M.A. Mohammed
      Introduction Multiple sclerosis (MS) is an autoimmune disease that attacks the central nervous system, causing the appearance of focal areas of inflammation and demyelination. A detailed study of MS would offer a better understanding of the causes of increased number of MS cases in the Arab Gulf countries. Materials and Methods A comprehensive literature search was performed to extract data regarding MS in general and MS in Arabian Gulf countries in specific. Only peer-reviewed, full-text articles published in English were included. Results Data have shown a noticeable increase in cases of MS in the Arab Gulf countries. Although the underlying causes still remain elusive, many factors have been proposed to influence MS. This review will discuss the factors influencing MS, correlate their effects with disease pathology, their interaction in the context of disease development, and try to explain the increased number of MS in Arabian Gulf countries. Conclusion Understanding MS development could open new doors for the treatment of MS, as well as initiate novel target therapies for citizens of Arab Gulf countries.

      PubDate: 2017-03-07T19:32:28Z
      DOI: 10.1016/j.pathog.2016.04.001
      Issue No: Vol. 3, No. 2 (2017)
       
  • Development and validation of a TaqMan Array for cancer mutation analysis

    • Authors: Hugh Kikuchi; Anne Reiman; Jenifer Nyoni; Katherine Lloyd; Richard Savage; Tina Wotherspoon; Lisa Berry; David Snead; Ian A. Cree
      Pages: 1 - 8
      Abstract: Publication date: February 2016
      Source:Pathogenesis, Volume 3, Issue 1
      Author(s): Hugh Kikuchi, Anne Reiman, Jenifer Nyoni, Katherine Lloyd, Richard Savage, Tina Wotherspoon, Lisa Berry, David Snead, Ian A. Cree
      Introduction Optimal cancer treatment with targeted agents requires rapid, comprehensive and accurate molecular assays to analyse actionable oncogenic mutations across multiple tumour types. Materials and Methods We describe a PCR panel based on the 384 well TaqMan Array® (Thermo Fisher Scientific). This allows measurement of common RAS (NRAS and KRAS), EGFR and BRAF mutations in a single assay (the REB Array), analysing 44 mutations in 7 samples per plate. This retrospective study includes 96 patients with NSCLC (n = 42), colorectal cancer (n = 26), and melanoma (n = 28) with previous mutational analysis. Samples with discrepant results were sequenced to confirm the result. Results The REB achieved 93% concordance with the Therascreen EGFR assay (Qiagen), 95% concordance with the KRAS castPCR assay (Thermo Fisher), and 100% concordance with the cobas BRAF assay (Roche). There were 2 true discrepancies, most likely a result of sample quality or differences in sensitivity between the assays that depend on set thresholds to determine the presence of mutations. Analysis of the performance of the REB Array gave an overall sensitivity of 92%, with a positive predictive value of 100% and negative predictive value of 84.24%. Conclusion The REB array is comparable to competing PCR methods with the additional advantages of a broader range of mutations, simplified manual handling, and reduced overall cost per sample.

      PubDate: 2017-03-07T19:32:28Z
      DOI: 10.1016/j.pathog.2016.02.001
      Issue No: Vol. 3, No. 1 (2017)
       
  • Biology of peripheral T cell lymphomas – Not otherwise specified: Is
           something finally happening'

    • Authors: Francesco Maura; Anna Dodero; Cristiana Carniti; Niccolò Bolli
      Pages: 9 - 18
      Abstract: Publication date: February 2016
      Source:Pathogenesis, Volume 3, Issue 1
      Author(s): Francesco Maura, Anna Dodero, Cristiana Carniti, Niccolò Bolli
      Introduction Peripheral T-cell lymphomas represent a rare, heterogeneous group of nodal and extra-nodal mature T-cell lymphomas. Among those, the subtype of PTCL not otherwise specified (PTCL-NOS) account for about 25% of all PTCL. While other PTCL subtypes are increasingly recognized as discrete entities based on specific genotypic and phenotypic alterations, the diagnosis of PTCL-NOS is currently performed on an “exclusion criteria” model, since PTCL-NOS lack pathognomonic features. Methods In this review, we describe the classical pathological features of PTCL-NOS and integrate them with the most recent molecular findings. Results Thanks to gene expression profiling and next generation sequencing approaches, we have recently improved our knowledge of PTCL in general and PTCL-NOS in particular. Indeed, specific patterns of gene expression were reported to segregate PTCL into more homogeneous subtypes associated with distinct clinical outcome. Furthermore, we describe how immunophenotypic, expression and mutational data helped to better define a new subgroup of PTCL-NOS displaying a global profile close to T Follicular Helper cell elements. Finally, we review how these new acquisitions are changing the current diagnostic approach to PTCL-NOS, and how phenotypic features and oncogenic pathways operative in these lymphomas are becoming targets of novel treatments. Conclusion Although no recurrent and specific biological aberrations have been discovered yet, novel integrated genomic and transcriptomics approaches are significantly improving our knowledge of PTCL biology and support the development of new powerful diagnostic and prognostic markers, as well as targets of future therapies.

      PubDate: 2017-03-07T19:32:28Z
      DOI: 10.1016/j.pathog.2016.02.002
      Issue No: Vol. 3, No. 1 (2017)
       
  • Pathogenesis of splenic marginal zone lymphoma

    • Authors: Ming-Qing Du
      Pages: 11 - 20
      Abstract: Publication date: November 2015
      Source:Pathogenesis, Volume 2, Issue 4
      Author(s): Ming-Qing Du
      Splenic marginal zone lymphoma (SMZL) is a distinct low grade B-cell lymphoma with an immunophenotype similar to that of splenic marginal zone B-cells. Like the normal splenic marginal zone B-cells, SMZLs also show variable features in somatic mutations of their rearranged immunoglobulin genes, with ∼90% of cases harbouring somatic mutations but at remarkably variable degrees, suggesting that SMZL may have multiple cell of origins, deriving from the heterogeneous B-cells of the splenic marginal zone. Notably, ∼30% of SMZLs show biased usage of IGHV1-2*04, with the expressed BCR being potentially polyreactive to autoantigens. Recent exome and targeted sequencing studies have identified a wide spectrum of somatic mutations in SMZL with the recurrent mutations targeting multiple signalling pathways that govern the development of splenic marginal zone B-cells. These recurrent mutations occur in KLF2 (20–42%), NOTCH2 (6.5–25%), NF-κB (CARD11 ∼7%, IKBKB ∼7%, TNFAIP3 7–13%, TRAF3 5%, BIRC3 6.3%) and TLR (MYD88 5–13%) signalling pathways. Interestingly, the majority of SMZL with KLF2 mutation have both 7q32 deletion and IGHV1-2 rearrangement, and these cases also have additional mutations in NOTCH2, or TNFAIP3, or TRAF3. There is a potential oncogenic cooperation among concurrent genetic changes, for example between the IGHV1-2 expressing BCR and KLF2 mutation in activation of the canonical NF-κB pathway, and between KLF2 and TRAF3 mutations in activation of the non-canonical NF-κB pathway. These novel genetic findings have provided considerable insights into the pathogenesis of SMZL and will stimulate the research in both normal and malignant marginal zone B-cells.

      PubDate: 2017-03-11T22:35:42Z
      DOI: 10.1016/j.pathog.2015.07.001
      Issue No: Vol. 2, No. 4 (2017)
       
  • Multiplex PCR assay for the simultaneous detection of C. perfringens,
           P. aeruginosa and K. pneumoniae

    • Authors: Pradeepkiran Jangampalli Adi; Ramesh Babu Pappithi; Praveen Chakravarthi Veeraraghavulu; Bhaskar Matcha
      Pages: 21 - 26
      Abstract: Publication date: November 2015
      Source:Pathogenesis, Volume 2, Issue 4
      Author(s): Pradeepkiran Jangampalli Adi, Ramesh Babu Pappithi, Praveen Chakravarthi Veeraraghavulu, Bhaskar Matcha
      Introduction Rapid diagnosis of bacterial infection is an important for patient management and appropriate therapy during the early phase of bacteria-induced disease. Among the existing techniques for identifying pathogens were less sensitive and time-consuming processes. PCR has the benefits of excellent sensitivity, resolution and reproducibility. Materials and methods A multiplex PCR assay was designed for simultaneous detection and diagnosis of C. perfringens, P. aeruginosa and K. pneumoniae in different clinical samples. A total of 46 clinical samples of patients suspected with the infections were obtained from Sri Venkateswara Institute of Medical Sciences, and used in the present study as test samples for detecting the pathogens. Results and conclusions Through this approach, the above pathogens were detected simultaneously with high specificity in pure cultures and from the blood and urine samples. The results were correlated with normal diagnostic process, and proved to be more sensitive and specific diagnostic technique in the simultaneous detection of C. perfringens, P. aeruginosa and K. pneumoniae.

      PubDate: 2017-03-11T22:35:42Z
      DOI: 10.1016/j.pathog.2015.09.001
      Issue No: Vol. 2, No. 4 (2017)
       
  • HER2: An emerging biomarker in non-breast and non-gastric cancers

    • Authors: Norhayati Omar; Benedict Yan; Manuel Salto-Tellez
      Pages: 1 - 9
      Abstract: Publication date: August 2015
      Source:Pathogenesis, Volume 2, Issue 3
      Author(s): Norhayati Omar, Benedict Yan, Manuel Salto-Tellez
      Introduction HER2, a member of the human epidermal growth factor (HER) family of transmembrane tyrosine kinases, has been of considerable interest in oncology due to its significant role in the pathogenesis of various cancer types. Materials and methods In this article, we review current data on HER2 as a potential biomarker in cancers other than breast and gastric by conducting an electronic database search using Pubmed. Results The existing literature provides evidence that HER2 protein overexpression and genomic alterations exist in a subset of patients with non-breast and non-gastric cancers, and hints at the promise of anti-HER2 targeted therapy in these patients. Conclusion Moving forward, the rigorous evaluation of HER2 (protein and genomic) status as a predictive biomarker will be necessary to bring anti-HER2 therapeutics for non-breast and non-gastric cancers to the clinic.

      PubDate: 2017-03-11T22:35:42Z
      DOI: 10.1016/j.pathog.2015.05.002
      Issue No: Vol. 2, No. 3 (2017)
       
  • An audit into use of minimum dataset reporting of skin cancers in the
           North of England Cancer Network

    • Authors: Paul D. Barrett; Hannah E. Barrett
      Pages: 5 - 8
      Abstract: Publication date: 2015
      Source:Pathogenesis, Volume 2, Issues 1–2
      Author(s): Paul D. Barrett, Hannah E. Barrett
      Aim We report an audit of skin cancers reported by pathologists across the North of England Cancer Network. Method We examined 386 reports to determine whether core data items recommended by the National Minimum dataset had been included in the pathology reports. Results Only 115 of the 386 reports (30%) had all the expected data items compared to the expected standard of 90%. Melanoma reports were more often fully compliant (42%) compared with non-melanoma skin cancer (26%). Of 203 proforma reports, 112 were considered complete compared to only 3 of 183 free text reports. This confirms once again the value of a structured report in capturing all required core data items. The data items accounting for the majority of the deficiencies were tumour subtype, T stage and particularly risk status. Discussion We consider the reasons behind the poor level of compliance and consider opportunities that may exist to aid pathologists in generating clinically more useful reports of skin cancers.

      PubDate: 2017-03-11T22:35:42Z
      DOI: 10.1016/j.pathog.2015.05.003
      Issue No: Vol. 2, No. 1-2 (2017)
       
  • The impact of next generation sequencing technologies on haematological
           research – A review

    • Authors: Jessica S. Black; Manuel Salto-Tellez; Ken I. Mills; Mark A. Catherwood
      Pages: 9 - 16
      Abstract: Publication date: 2015
      Source:Pathogenesis, Volume 2, Issues 1–2
      Author(s): Jessica S. Black, Manuel Salto-Tellez, Ken I. Mills, Mark A. Catherwood
      Next-generation sequencing (NGS) technologies have begun to revolutionize the field of haematological malignancies through the assessment of a patient's genetic makeup with a minimal cost. Significant discoveries have already provided a unique insight into disease initiation, risk stratification and therapeutic intervention. Sequencing analysis will likely form part of the routine diagnostic testing in the future. However, a number of important issues need to be addressed for that to become a reality with regard to result interpretation, laboratory workflow, data storage and ethical issues. In this review we summarize the contribution that NGS has already made to the field of haematological malignancies. Finally, we discuss the challenges that NGS technologies will bring in relation to data storage, ethical and legal issues and laboratory validation. Despite these challenges, we predict that high-throughput DNA sequencing will redefine haematological malignancies based on individualized genomic analysis.

      PubDate: 2017-03-11T22:35:42Z
      DOI: 10.1016/j.pathog.2015.05.004
      Issue No: Vol. 2, No. 1-2 (2017)
       
  • Low-grade fibromyxoid sarcoma of the transverse colon: A case report

    • Authors: I.S. Farrell; K. Brelsford; W. Salman; C.J. Smart
      Pages: 1 - 3
      Abstract: Publication date: 2014
      Source:Pathogenesis, Volume 1, Issue 1
      Author(s): I.S. Farrell, K. Brelsford, W. Salman, C.J. Smart
      A 52 year old lady presented with non-specific abdominal symptoms and menorrhagia. Ultrasound scan revealed an incidental finding of a large soft tissue mass. This was further characterised with a CT scan which revealed a 15 cm × 10 cm × 7 cm multilobulated mass. This was removed via a subtotal colectomy. Initial histology was reported as a most likely diagnosis of gastro-intestinal stromal tumour (GIST) but further characterisation revealed this to be a low-grade fibromyxoid sarcoma. This is only the second reported case of low-grade fibromyxoid sarcoma of the colon and would potentially have been missed had not the sample been sent for second opinion at a regional specialist centre.

      PubDate: 2017-03-11T22:35:42Z
      DOI: 10.1016/j.pathog.2014.07.001
      Issue No: Vol. 1, No. 1 (2017)
       
  • Aims and Scope/Editorial Board

    • Abstract: Publication date: November 2015
      Source:Pathogenesis, Volume 2, Issue 4


      PubDate: 2017-03-11T22:35:42Z
       
  • Aims and Scope/Editorial Board

    • Abstract: Publication date: August 2015
      Source:Pathogenesis, Volume 2, Issue 3


      PubDate: 2017-03-11T22:35:42Z
       
  • Aims and Scope/Editorial Board

    • Abstract: Publication date: 2015
      Source:Pathogenesis, Volume 2, Issues 1–2


      PubDate: 2017-03-11T22:35:42Z
       
  • Liquid biopsy for cancer patients: Principles and practice

    • Authors: Ian Cree
      Abstract: Publication date: 2015
      Source:Pathogenesis, Volume 2, Issues 1–2
      Author(s): Ian A. Cree
      Liquid biopsy has the potential to provide information about cancers without invasive biopsy, using circulating biomarkers. These include proteins, RNA and DNA. They can be used in detection, diagnosis, monitoring and detection of recurrence. While protein-based tumour markers have been used in routine pathology for many years, the ability to detect mutations in circulating DNA is relatively new, and poised to enter clinical practice. A number of issues remain, and it is important that such markers are fully validated before they enter clinical practice. Evidence of clinical utility and cost effectiveness are major hurdles, but it is likely that the use of liquid biopsy in defined settings could benefit cancer patients substantially.

      PubDate: 2017-03-11T22:35:42Z
       
  • Aims and Scope/Editorial Board

    • Abstract: Publication date: 2014
      Source:Pathogenesis, Volume 1, Issue 1


      PubDate: 2017-03-11T22:35:42Z
       
  • Aims and Scope/Editorial Board

    • Abstract: Publication date: May 2016
      Source:Pathogenesis, Volume 3, Issue 2


      PubDate: 2017-03-07T19:32:28Z
       
  • Aims and Scope/Editorial Board

    • Abstract: Publication date: February 2016
      Source:Pathogenesis, Volume 3, Issue 1


      PubDate: 2017-03-07T19:32:28Z
       
 
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