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  Subjects -> ENGINEERING (Total: 2266 journals)
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ENGINEERING (1197 journals)                  1 2 3 4 5 6 | Last

Showing 1 - 200 of 1205 Journals sorted alphabetically
3 Biotech     Open Access   (Followers: 7)
3D Research     Hybrid Journal   (Followers: 19)
AAPG Bulletin     Full-text available via subscription   (Followers: 5)
AASRI Procedia     Open Access   (Followers: 14)
Abstract and Applied Analysis     Open Access   (Followers: 3)
Aceh International Journal of Science and Technology     Open Access   (Followers: 2)
ACS Nano     Full-text available via subscription   (Followers: 207)
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Acta Polytechnica : Journal of Advanced Engineering     Open Access   (Followers: 1)
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Acta Universitatis Cibiniensis. Technical Series     Open Access  
Active and Passive Electronic Components     Open Access   (Followers: 7)
Adaptive Behavior     Hybrid Journal   (Followers: 10)
Adıyaman Üniversitesi Mühendislik Bilimleri Dergisi     Open Access  
Adsorption     Hybrid Journal   (Followers: 4)
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American Journal of Engineering Education     Open Access   (Followers: 9)
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American Journal of Industrial and Business Management     Open Access   (Followers: 23)
Analele Universitatii Ovidius Constanta - Seria Chimie     Open Access  
Annals of Combinatorics     Hybrid Journal   (Followers: 3)
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Applicable Algebra in Engineering, Communication and Computing     Hybrid Journal   (Followers: 2)
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Asian Journal of Applied Sciences     Open Access   (Followers: 2)
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Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 9)
Assembly Automation     Hybrid Journal   (Followers: 2)
at - Automatisierungstechnik     Hybrid Journal   (Followers: 1)
ATZagenda     Hybrid Journal  
ATZextra worldwide     Hybrid Journal  
Australasian Physical & Engineering Sciences in Medicine     Hybrid Journal   (Followers: 1)
Australian Journal of Multi-Disciplinary Engineering     Full-text available via subscription   (Followers: 2)
Autonomous Mental Development, IEEE Transactions on     Hybrid Journal   (Followers: 7)
Avances en Ciencias e Ingeniería     Open Access  
Balkan Region Conference on Engineering and Business Education     Open Access   (Followers: 1)
Bangladesh Journal of Scientific and Industrial Research     Open Access  
Basin Research     Hybrid Journal   (Followers: 3)
Batteries     Open Access   (Followers: 3)
Bautechnik     Hybrid Journal   (Followers: 1)
Bell Labs Technical Journal     Hybrid Journal   (Followers: 24)
Beni-Suef University Journal of Basic and Applied Sciences     Open Access   (Followers: 3)
BER : Manufacturing Survey : Full Survey     Full-text available via subscription   (Followers: 2)
BER : Motor Trade Survey     Full-text available via subscription   (Followers: 1)
BER : Retail Sector Survey     Full-text available via subscription   (Followers: 2)
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BER : Survey of Business Conditions in Manufacturing : An Executive Summary     Full-text available via subscription   (Followers: 3)
BER : Survey of Business Conditions in Retail : An Executive Summary     Full-text available via subscription   (Followers: 3)
Bharatiya Vaigyanik evam Audyogik Anusandhan Patrika (BVAAP)     Open Access   (Followers: 1)
Biofuels Engineering     Open Access  
Biointerphases     Open Access   (Followers: 1)
Biomaterials Science     Full-text available via subscription   (Followers: 8)
Biomedical Engineering     Hybrid Journal   (Followers: 16)
Biomedical Engineering and Computational Biology     Open Access   (Followers: 13)
Biomedical Engineering Letters     Hybrid Journal   (Followers: 5)
Biomedical Engineering, IEEE Reviews in     Full-text available via subscription   (Followers: 16)
Biomedical Engineering, IEEE Transactions on     Hybrid Journal   (Followers: 31)
Biomedical Engineering: Applications, Basis and Communications     Hybrid Journal   (Followers: 5)
Biomedical Microdevices     Hybrid Journal   (Followers: 8)
Biomedical Science and Engineering     Open Access   (Followers: 4)
Biomedizinische Technik - Biomedical Engineering     Hybrid Journal  
Biomicrofluidics     Open Access   (Followers: 4)
BioNanoMaterials     Hybrid Journal   (Followers: 1)
Biotechnology Progress     Hybrid Journal   (Followers: 39)
Boletin Cientifico Tecnico INIMET     Open Access  
Botswana Journal of Technology     Full-text available via subscription  
Boundary Value Problems     Open Access   (Followers: 1)
Brazilian Journal of Science and Technology     Open Access   (Followers: 2)
Broadcasting, IEEE Transactions on     Hybrid Journal   (Followers: 10)
Bulletin of Canadian Petroleum Geology     Full-text available via subscription   (Followers: 14)
Bulletin of Engineering Geology and the Environment     Hybrid Journal   (Followers: 3)
Bulletin of the Crimean Astrophysical Observatory     Hybrid Journal  
Cahiers, Droit, Sciences et Technologies     Open Access  
Calphad     Hybrid Journal  
Canadian Geotechnical Journal     Full-text available via subscription   (Followers: 14)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 40)
Case Studies in Engineering Failure Analysis     Open Access   (Followers: 7)
Case Studies in Thermal Engineering     Open Access   (Followers: 4)
Catalysis Communications     Hybrid Journal   (Followers: 6)
Catalysis Letters     Hybrid Journal   (Followers: 3)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 8)
Catalysis Science and Technology     Free   (Followers: 6)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 3)
Catalysis Today     Hybrid Journal   (Followers: 5)
CEAS Space Journal     Hybrid Journal  
Cellular and Molecular Neurobiology     Hybrid Journal   (Followers: 4)
Central European Journal of Engineering     Hybrid Journal   (Followers: 1)
CFD Letters     Open Access   (Followers: 6)
Chaos : An Interdisciplinary Journal of Nonlinear Science     Hybrid Journal   (Followers: 2)
Chaos, Solitons & Fractals     Hybrid Journal   (Followers: 3)
Chinese Journal of Catalysis     Full-text available via subscription   (Followers: 2)
Chinese Journal of Engineering     Open Access   (Followers: 2)
Chinese Science Bulletin     Open Access   (Followers: 1)
Ciencia e Ingenieria Neogranadina     Open Access  
Ciencia en su PC     Open Access   (Followers: 1)
Ciencias Holguin     Open Access   (Followers: 1)
CienciaUAT     Open Access  
Cientifica     Open Access  
CIRP Annals - Manufacturing Technology     Full-text available via subscription   (Followers: 10)
CIRP Journal of Manufacturing Science and Technology     Full-text available via subscription   (Followers: 13)
City, Culture and Society     Hybrid Journal   (Followers: 20)
Clay Minerals     Full-text available via subscription   (Followers: 9)
Clean Air Journal     Full-text available via subscription   (Followers: 2)
Coal Science and Technology     Full-text available via subscription   (Followers: 4)
Coastal Engineering     Hybrid Journal   (Followers: 10)
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Cogent Engineering     Open Access   (Followers: 2)
Cognitive Computation     Hybrid Journal   (Followers: 4)
Color Research & Application     Hybrid Journal   (Followers: 1)
COMBINATORICA     Hybrid Journal  
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Combustion, Explosion, and Shock Waves     Hybrid Journal   (Followers: 13)
Communications Engineer     Hybrid Journal   (Followers: 1)
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Composite Interfaces     Hybrid Journal   (Followers: 5)
Composite Structures     Hybrid Journal   (Followers: 241)
Composites Part A : Applied Science and Manufacturing     Hybrid Journal   (Followers: 174)
Composites Part B : Engineering     Hybrid Journal   (Followers: 215)
Composites Science and Technology     Hybrid Journal   (Followers: 160)
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Journal Cover Beni-Suef University Journal of Basic and Applied Sciences
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2314-8535
   Published by Elsevier Homepage  [3043 journals]
  • Morphological, Histochemical and Computed Tomography on the Vomeronasal
           Organ (Jacobson's Organ) of Egyptian Native Breeds of Goats (Capra hircus)
           

    • Authors: Usama Kamal Moawad; Ashraf Sayed Awaad; BahaaEldeen Ali Abedellaah
      Abstract: Publication date: Available online 24 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Usama Kamal Moawad, Ashraf Sayed Awaad, BahaaEldeen Ali Abedellaah
      Background The vomeronasal organ (Jacobson organ) is a chemosensory paired tubular organ located on both sides of the nasal septum at its base. It plays an essential role in reproduction process and social behaviors. Objective The current study investigated both anatomical and histological structure of the vomeronasal organ (VNO) in Egyptian native breeds of goats using cross sectional anatomy, histological techniques and computed tomography (CT). Methodology A total of thirty heads obtained from adult and apparently healthy goats of both sexes were collected from Beni-Suef slaughterhouse in Beni-Suef province, Egypt then subjected to anatomical, histological and computed topographical studies. Results Grossly, the VNO appeared as two blind ducts on the either sides of the nasal septum at the floor of nasal cavity extending from the nasal opening of incisive papilla rostrally to the upper 2nd premolar teeth caudally. It connected with mouth by two nasopalatine ducts. The histological examinations revealed two types of lining epithelium; non sensory type lining the cranial portion and the lateral wall of the middle portion of the vomeronasal duct (VND), whereas an olfactory type was the lining epithelium of the medial wall of the middle and the whole caudal portions. The lamina propria submucosa exhibited vascular loose connective tissues, serous glands, nerve bundles and encapsulated by hyaline cartilage. Conclusion The obtaining olfactory epithelium in VNO may indicate an essential role of this organ in sexual relationships and sociosexual behaviors through perception of pheromones.

      PubDate: 2017-03-27T14:57:24Z
      DOI: 10.1016/j.bjbas.2017.03.003
       
  • Supplementary studies of Pleurogenoides medians (Digenea:
           Lecithodendriidae) infecting the Marsh frog Rana Ridibunda (Amphibia:
           Ranidae) in Egypt

    • Authors: Rewaida Abdel-Gaber; Sherein Maher; Reem Kamel; Nashwa El Deeb
      Abstract: Publication date: Available online 9 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Rewaida Abdel-Gaber, Sherein Maher, Reem Kamel, Nashwa El Deeb
      Pleurogenoides medians, a digenean lecithodendriid trematode, parasitize numerous aquatic vertebrate species including frogs, freshwater fish, urodeles and anurans. In the present study, a total of 190 out of 300 (63.33%) marsh frogs Rana Ridibunda were found to be infected with this digenean parasite. The highest percentage of infection was recorded in winter reaching 93.33%, and the lowest value was recorded to be 6.66% during summer. Prevalence and intensity of infection were positively correlated with the host size. Host sex showed no effect in this respect. Morphological studies based on light and scanning electron microscopy revealed that the adult worms characterized by small body size measured 1.980-2.430 (2.205±0.1) mm long and 0.870-1.20 (9.87±0.01) mm wide with spines of similar size distributed all over the body surface; oral sucker is sub-terminal and measured 0.180-0.230 (0.203±0.01) mm long and 0.120-0.180 (0.150±0.01) mm wide; ventral sucker is smaller than the oral sucker, post-ovarian located at 1/3 level from the anterior end and measured 0.080-0.102 (0.090±0.001) mm long and 0.100-0140 (0.120±0.001) mm wide; two symmetrical testes were located near the cecal termination on both sides of the ventral sucker, measured 0.153-0.193 (0.176±0.01) mm long and 0.160-0.192 (0.175±0.01) mm wide; pre-acetabular ovary was present and measured 0.130-0.150 (0.140±0.01) mm long and 0.100-0.130 (0.120±0.01) mm wide; vitellaria are extra-caecal and extended from the level of the pharynx to a level slightly beyond the ovary. By comparing the recovered parasite with different species of the same genus from different hosts having different localities, it was found that the present species morphometrically more or less different from the comparable species and the only similar species was P. medians described previously from the common toad Bufo bufo by having all similar characteristic features. In addition, the present study was considered as the first report for the occurrence of this lecithodendriid species infecting the marsh frog in Egypt.

      PubDate: 2017-03-15T14:48:32Z
      DOI: 10.1016/j.bjbas.2017.03.001
       
  • Cypermethrin-induced histopathological, ultrastructural and biochemical
           changes in liver of albino rats: The protective role of Propolis and
           Curcumin

    • Authors: Manal Abdul-Hamid; Nadia Moustafa; Abd El Mawgoud Abd Alla Asran; Lila Mowafy
      Abstract: Publication date: Available online 8 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Manal Abdul-Hamid, Nadia Moustafa, Abd El Mawgoud Abd Alla Asran, Lila Mowafy
      Cypermethrin (CYP), an insecticide belongs to a synthetic pyrethroid, is used for agriculture and household applications. The present study aimed to examine the toxic effects of CYP on rat liver and to clarify the hepatoprotective effects of propolis (PRO) and curcumin (CUR) against CYP. This study was assessed in male albino rats, each weighting (120-150 g). The rats were equally divided into six groups as follow; the 1st control group, 2nd PRO group (100 mg/kg/day) and 3rd CUR group (100 mg/kg/day). While 4th, 5th and 6th groups were orally treated with CYP (30 mg/kg/day), CYP plus PRO and CYP plus CUR, respectively for 28 days. The present study revealed that CYP-induced significant increase in hepatic markers enzymes (ALT, AST and ALP) and elevation in MDA concomitant with significant decrease of SOD and GPx levels. Histological and histochemical results revealed extensive vacuolar degeneration of hepatocytes, fatty change, blood vessel congestion and fibrosis in the liver of CYP- treated group and depletion of glycogen, protein and DNA. Moreover, ultrastructural observations showed vacuolation, damage of mitochondria and nuclear changes. On the other hand, treatment with PRO and CUR led to an obvious improvement of the injured liver tissues and ameliorating the damaging effects of CYP. In conclusion, PRO is markedly effective than CUR in protecting rats against CYP-induced histopathological, ultrastructural and biochemical changes. This protection may be due to its antioxidant properties and scavenging abilities against active free radicals.

      PubDate: 2017-03-15T14:48:32Z
      DOI: 10.1016/j.bjbas.2017.03.002
       
  • Reproductive responses of primiparous and multiparous Holstein cows
           submitted to presynch-ovsynch protocol

    • Authors: R.L. Abdel Aziz; A. Abdel-Wahab
      Abstract: Publication date: Available online 2 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): R.L. Abdel Aziz, A. Abdel-Wahab
      The specific objective of this study was to determine the reproductive responses of primiparous (n=446) and multiparous (n=726) Holstein cows submitted to 12-day presynch-ovsynch protocol under the Egyptian circumstances. Distribution of inter-estrus intervals (IEI) and conception rate to first insemination (FICR) was compared between primiparous and multiparous cows. Furthermore, Seasonal variations of heat detection rate (HDR), conception rate (CR) and pregnancy rate (PR) were investigated. Short IEI tended to be higher in multiparous cows (23.8 vs 20.44%, P=0.09) compared to primiparous cows. In addition, the incidence of prolonged IEI was decreased from 21.53% in multiparous cows to 16.77% in primiparous cows. On contrary, normal length IEI was 62.78% in primiparous cows, higher than that observed in multiparous cows (54.67%). Moreover, primiparous cows inseminated earlier postpartum (<50 days) achieved higher FICR (31.79%) than multiparous cows (24.46%). Controversially, a tendency toward higher FICR was observed for multiparous cows inseminated after 70 days postpartum (31.89% vs. 23.17%, respectively; P=0.15). No clear variations in HDR were observed among different seasons, whereas greater CR and PR (P<0.05) were achieved by cows inseminated during Winter (35.37 and 24.90) and Spring (36.36 and 24.68), compared to those inseminated during Summer (10 and 6.6) and Autumn (21.59 and 15.63). Conceivably, our results demonstrate that primiparous Holstein cows responded better than multiparous cows to the 12-day presynch-ovsynch protocol as evidenced by higher incidence of normal length IEI, lower incidence of short and prolonged IEI and higher FICR. Furthermore, Summer season had significant negative and delayed effects on fertility of Holstein cows submitted to the 12-day Presynch-ovsynch protocol.

      PubDate: 2017-03-07T14:42:59Z
      DOI: 10.1016/j.bjbas.2017.02.005
       
  • Parameter identification for nonlinear damping coefficient from
           large-amplitude ship roll motion using wavelets

    • Authors: D. Sathyaseelan; G. Hariharan; K. Kannan
      Abstract: Publication date: Available online 27 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): D. Sathyaseelan, G. Hariharan, K. Kannan
      In this paper, we have introduced an efficient Legendre wavelet spectral method (LWSM) to ship roll motion model for investigating the nonlinear damping coefficients. The accuracy of the proposed method is assessed by rolling with an initial amplitude using nonlinear type of equations. To the best of our knowledge until now there is no rigorous wavelet solution has been reported for the above model. Convergence analysis of the proposed method is discussed. The operational matrix of derivative is utilized to convert a ship roll motion equation into a set of algebraic equations. Accurate coefficients can be easily obtained for large rolling angles up to the amplitude at the maximum value of the restoring moment using wavelets. Some numerical examples are given to show the validity and applicability of the proposed wavelet method. Moreover the use of Legendre wavelets is found to be simple,flexible, accurate, efficient and small computation cost.

      PubDate: 2017-03-01T14:39:16Z
      DOI: 10.1016/j.bjbas.2017.02.003
       
  • Meta-analysis of Staphylococcal Diarrhea in Some Developing African
           Countries

    • Authors: George P. Einstein; Orien L. Tulp; Temitope C. Oyesile; Olayide F. Obidi
      Abstract: Publication date: Available online 22 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): George P. Einstein, Orien L. Tulp, Temitope C. Oyesile, Olayide F. Obidi
      Staphylococcal diarrhea is a common gastro-intestinal illness caused by poor water supply and unhygienic food preparation. Although, about 70% of diarrheal cases per year have been attributed to the consumption of contaminated foods, in Africa, few studies have reported the incidence of Staphylococcus-related diarrhea and the implicated virulence factors. We investigated the implications of common factors such as age of children, age of mothers, maternal level of education, gender of children, overall bacteria isolated, sanitary condition status and feeding type of mothers on the burden of staphylococcal diarrhea. A literature search was performed using Pubmed, Googlescholar, American society for microbiology (ASM) journals and other sources. The quality of studies was assessed. Adjusted odds ratios with 95% confidence intervals (CI) for the occurrence of staphylococcus aureus amongst other causes were extracted. For each study, a multivariate logistic regression analysis of the adjusted odds ratio was performed to identify the risk factors on the burden of staphylococcal diarrhea. Six case-control studies were included in the meta–analysis. Quality of individual studies rages from 0.57–0.84 (median, 0.69). Meta-analysis gave pooled odds ratios 3.27 (95% CI; 2.88–4.17). The results identified inadequate sanitary conditions and type of feeding as major risk factors.

      PubDate: 2017-03-01T14:39:16Z
      DOI: 10.1016/j.bjbas.2017.02.004
       
  • Flow Improvement at Pump Intake by the Use of Baffle Posts

    • Authors: Mohamed Mohamed Abdellatif Mohamed
      Abstract: Publication date: Available online 16 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed Mohamed Abdellatif Mohamed
      Poor design of intake structures surrounding the hydraulic pump causes undesirable flow problems. These flow problems are in the form of severe vortices, and/or uneven flow distribution at pump intake. There are several methods in the literature to suppress such vortices but such methods might have an adverse impact on the operation and maintenance of the intake structure. In this paper, a new approach was investigated to reduce the vortex activity without any adverse impacts on the operation process. This approach depends on installing baffle posts on the top of the upstream side and the offshore long side of the sedimentation basin of the intake structure. An existing physical model of undistorted scale 1:38 was utilized to reduce the vortex activity using baffle posts. The model shows that baffle posts are effective in eliminating the vortex activity and hence improving the approach flow at the intake structure.

      PubDate: 2017-02-22T02:34:21Z
      DOI: 10.1016/j.bjbas.2017.02.002
       
  • Underutilized Luffa cylindrica sponge: A local bio-adsorbent for the
           removal of Pb (II) pollutant from water system

    • Authors: Adewale Adewuyi; Fabiano Vargas Pereira
      Abstract: Publication date: Available online 16 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Adewale Adewuyi, Fabiano Vargas Pereira
      Biosorption of Pb2+ ions from aqueous solution onto Luffa cylindrica sponge as adsorbent (LCSA) was investigated in batch adsorption system. LCSA was characterized by X-ray Diffraction analysis technique (XRD), Scanning Electron Microscopy (SEM) coupled with energy dispersive spectroscopy (EDS), Fourier Transform Infrared spectrometer (FTIR), particle size dispersion, zeta potential, thermogravimetric analysis (TGA), and Brunauer-Emmett-Teller (BET) surface area analyzer. The sorption of Pb2+ ions by LCSA was subjected to equilibrium, thermodynamics and kinetic studies and was carried out by considering the effects of pH, initial metal ions concentration, contact time and temperature. BET surface area of LCSA was 6.00 m2/g with mean distribution size of 0.02 micron while the zeta potential was found to increase as the value of pH increased from 4-14. The findings revealed the maximum equilibrium adsorption capacity to be 75.853 mg/g. The process is chemisorptive and controlled by intra-particle diffusion. The values of thermodynamic parameters such as ΔGo, ΔHo and ΔSo showed a stable adsorbent-adsorbate (LCSA-Pb) configuration which is exothermic. The adsorption capacity of LCSA compared better than some natural bio-sorbent found in literature.

      PubDate: 2017-02-22T02:34:21Z
      DOI: 10.1016/j.bjbas.2017.02.001
       
  • Staphylococcal Bacteraemia among Human Immunodeficiency Virus Positive
           Patients at a Screening Center in Lagos, Nigeria

    • Authors: Solayide A. Adesida; Olusegun A. Abioye; Babajide S. Bamiro; Kehinde O. Amisu; Sikiru O. Badaru; Akitoye O. Coker
      Abstract: Publication date: Available online 3 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Solayide A. Adesida, Olusegun A. Abioye, Babajide S Bamiro, Kehinde O Amisu, Sikiru O Badaru, Akitoye O Coker
      Bacteraemia due to Staphylococcus aureus in Human immunodeficiency virus (HIV) - positive patients is associated with increased mortality rate. The present study aimed at determining the species distribution and occurrence of staphylococcal bacteremia in HIV – positive patients in Lagos, Nigeria. Staphylococcal blood stream infection in febrile HIV patients was investigated by culture technique. The antibiotic resistance pattern was investigated using the disk diffusion and methicillin resistance was confirmed by the salt agar methods. The genetic relatedness of S. aureus was determined using Pulsed Field Gel Electrophoresis (PFGE). Eighty-six patients comprising 47 (55%) female and 39 (45%) male, median aged 34 years took part in the study. Staphylococci were identified in 16 (18.6%) patients; 13 (15.1%) and 3 (3.5%) with single and dual Staphylococcus species respectively. The isolates consisted of S. aureus (7 patients), followed by S. haemolyticus (4 patients). Of the thirteen (13) antibiotics tested, isolates were resistant to ampicillin (AMP; 89.5%), tetracycline (TET; 68.4%), cloxacillin (CXC; 89.5%), oxacillin (OXA; 68.4%); chloramphenicol (CHL; 57.9%) and trimethoprim-sulphamethoxazole (SXT; 63.1%). The overall percentage of all the isolates resistant to gentamicin, erythromycin and amoxicillin-clavulanic acid was less than 50%. The isolates were ciprofloxacin and vancomycin susceptible. None of the isolates was positive for methicillin resistance except strain of S. haemolyticus. A significant genetic diversity was observed among S. aureus isolates with a predominant pulsotype A. The two isolates with pulsotype A also had identical resistotype (AMP, ERY, TET, CXC, SXT). Other PFGE patterns were represented by single isolates except pulsotype C which had a subtype. In these patients, the most frequent Staphylococcus species isolated was S. aureus and the results revealed that clonal dissemination of a virulent pulsotype of S. aureus among this population is plausible and should be a cause for concern.

      PubDate: 2017-02-09T02:25:16Z
      DOI: 10.1016/j.bjbas.2016.08.006
       
  • Efficacy and Toxicity of Once Versus Twice Daily Regimens of Amikacin in
           Febrile Neutropenic Pediatric Cancer Patients

    • Authors: Reda Abd-Elfattah; Alaa M.A. Elhdad; Ahmed Khames; Mohmed E.A. Abdelrahim; Samia A. Shouman
      Abstract: Publication date: Available online 1 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Reda Abd-Elfattah, Alaa M.A. Elhdad, Ahmed Khames, Mohmed E.A. Abdelrahim, Samia A. Shouman
      Purpose To compare the pharmacokinetic profile, clinical efficacy and toxicity of once-daily dosing of amikacin compared to twice-daily dosing among pediatric cancer patients with fever and neutropenia. Methods 134 Pediatric patients with hematological malignancies were randomly assigned to receive 15 mg/kg/day amikacin intravenously, either once or twice-daily dosing. For pharmacokinetics, two blood samples were obtained from each patient, the first sample was taken after 1hr from the beginning of infusion and the second sample was taken after 3hr from the first sample. Treatment success was considered when the patient improved without a change in the assigned antibiotic regimen or mortality from infection. Nephrotoxicity was assessed by following the increase in serum creatinine level. Results Pharmacokinetic data revealed superiority in once-daily dosing where Maximum concentration Cmax, Area under the concentration time curve in 24hr AUC24 and Elimination half-life t1/2 were a significantly higher while Minimum concentration Cmin, elimination rate constant Ke and clearance CL were significantly lower in once-daily dosing compared to the twice-daily dosing. Clinical response achieved in 76.8% in once-daily group compared to 69.2% in twice-daily group. Nephrotoxicity was recorded in two patients in once-daily group and six patients in the twice-daily group. After stratifying our patients according to age, a significant increase was observed in the volume of distribution V and CL in pediatrics with age ⩽five compared to >five years. Cmax and AUC24 were significantly lower in the age group of ⩽five years. Conclusions Clinical efficacy and nephrotoxicity were slightly improved in once-daily dosing compared to twice-daily dosing.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.006
       
  • Schistosomiasis haematobium prevalence among haematuric patients:
           parasitological and immuno-assay

    • Authors: Marwa A. Ghieth; Amr M. Lotfy
      Abstract: Publication date: Available online 1 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Marwa A. Ghieth, Amr M. Lotfy
      Schistosoma haematobium infection is a clinically important water born parasitic disease. This study was conducted to detect the prevalence of schistosomiasis haematobium among haematuric patients by microscopy and immunoassay. About 474 symptomized patients with urological manifestations and attending Beni-Suef University Hospital, Egypt were subjected to microhaematuria detection using dipstick reagent strip. Positive patients for microhaematuria were subjected to parasitological and immunological assay to detect S. haematobium eggs and antibodies. Haematuria prevalence was 17.7% (n=84). Egg of S. haematobium wasn’t detected by microscopic examination of urine sediment of all haematuric patients, immunological prevalence of Schistosoma antibodies was 46.4% (n=39). On comparing seropositive and seronegative patients for schistosomiasis antibodies none of the sociodemographic or clinical data were statistically significant. It was concluded that, negative microscopy for schistosomiasis doesn’t exclude infection. Combination of both clinical and epidemiological data in addition to sensitive diagnostic tools is essential for schistosomiasis. There is a critical need to develop more sensitive method to detect true prevalence of schistosomiasis.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.007
       
  • A new fuzzy regression model based on interval-valued fuzzy neural network
           and its applications to management

    • Authors: Somaye yeylaghi; Mahmood Otadi; Niloofar Imankhan
      Abstract: Publication date: Available online 28 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Somaye yeylaghi, Mahmood Otadi, Niloofar Imankhan
      In this paper, a novel hybrid method based on interval-valued fuzzy neural network for approximate of interval-valued fuzzy regression models, is presented. The work of this paper is an expansion of the research of real fuzzy regression models. In this paper interval-valued fuzzy neural network (IVFNN) can be trained with crisp and interval-valued fuzzy data. Here a neural network is considered as a part of a large field called neural computing or soft computing. Moreover, in order to find the approximate parameters, a simple algorithm from the cost function of the fuzzy neural network is proposed. Finally, we illustrate our approach by some numerical examples and compare this method with existing methods.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.004
       
  • Oxidative stress biomarkers in Clarias gariepinus (Burchel, 1822) exposed
           to Microcystin-LR

    • Authors: Isibor Patrick Omoregie
      Abstract: Publication date: Available online 20 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Isibor Patrick Omoregie
      Stress levels inflicted by microcystin-LR extracted from microcystis aeruginosa were assessed by estimating the effects on the oxidative stress biomarkers in the liver, muscle and gill tissues of Clarias garriepinus. Microcystin-LR was administered to the fish by injection into their intra-peritoneal cavity. Microcystin-LR induced the activities of mainly Glutathion-S-Transferase, Catalase and Superoxide dismutase in the liver on dose and temporal basis, while it inhibited the activities of Cytochrome P450 on temporal basis in the liver and gill. Results show that MC-LR significantly induced oxidative stress in the C. gariepinus. Findings show that 400 μg MC-LR/kg b.w. disrupted the antioxidant status of the fish without any external physical manifestation on the body. Microcystin-LR induced the activities of mainly GST, CAT and SOD in the liver on dose and temporal basis while it inhibited the activities of CYP450 on temporal basis in the liver and gill. The adopted MC-LR doses; particularly 400 μgMC-LR/kg b.w. inflicted stress on the fish without any external/ physical manifestation. MC-LR impacted on the antioxidant enzymes in the fish; in the order of liver > gill > muscle. This research has provided empirical evidences that 400 μg MC-LR/kg b.w induced oxidative stress in C. gariepinus in less than a month of exposure. This adopted level of MC-LR can be used as a warning signal in natural water bodies and commercial C. gariepinus ponds.

      PubDate: 2017-01-27T02:17:02Z
      DOI: 10.1016/j.bjbas.2017.01.005
       
  • Kinetics of inhibition of carbohydrate-metabolizing enzymes and mitigation
           of oxidative stress by Eucomis humilis Baker bulb

    • Authors: Mutiu Idowu Kazeem; Anofi Omotayo Tom Ashafa
      Abstract: Publication date: Available online 16 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mutiu Idowu Kazeem, Anofi Omotayo Tom Ashafa
      This study sought to evaluate the in-vitro inhibitory effect of E. humilis bulb extracts on diabetes related enzymes and oxidative stress. Aqueous, ethanol and hydro-ethanol extracts of E. humilis bulb were tested for their inhibitory effects on diabetes-linked enzymes (α-amylase, α-glucosidase, maltase and sucrase). This was followed by evaluation of the ability of these extracts to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl as well as superoxide radical, and iron chelation activity. Ethanol extract of E. humilis exhibited the most potent inhibitory effect on α-amylase (IC50: 79.12 μg/mL), α-glucosidase (IC50: 3.51 μg/mL), maltase (IC50: 37.69 μg/mL) and sucrase (IC50: 30.09 μg/mL). Ethanol extract of E. humilis also inhibited both α-amylase and sucrase non-competitively while α-glucosidase and maltase were both inhibited in a competitive manner. Ethanol extract also displayed most potent hydroxyl (EC50: 66.46 μg/mL) and superoxide (EC50: 22.30 μg/mL) radical scavenging abilities, while aqueous extract scavenges DPPH radical (EC50: 17.12 μg/mL) and chelate iron (EC50: 43.13 μg/mL) most. It can be concluded that ethanol extract of E. humilis displayed the most potent antidiabetic and antioxidant activities, and one of its mechanism of antidiabetic action is through the inhibition of carbohydrate-metabolizing enzymes.

      PubDate: 2017-01-20T02:11:43Z
      DOI: 10.1016/j.bjbas.2017.01.002
       
  • Seasonal fluctuation of trypanosomiasis in camels in North-West Egypt and
           effect of age, sex, location, health status and vector abundance on the
           prevalence

    • Authors: Hassan M. Sobhy; Safaa M. Barghash; Tahani S. Behour; Esam A. Razin
      Abstract: Publication date: Available online 9 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Hassan M. Sobhy, Safaa M. Barghash, Tahani S. Behour, Esam A. Razin
      Follow-up surveys of the blood parasites of the livestock and their possible vectors are recommended to assess their distribution and infection rates in different areas in Egypt and to plan control measures against their vectors. By this study, the authors have completed a comprehensive survey of the extent of Trypanosoma evansi infection in North-West Egypt from November 2014 to October 2015, using blood film examination and RoTat1.2 PCR-based assay. The present study was carried out in the frame of PROCAMED project, supported by the European Union (ENPI-Joint operational Programme of the Mediterranean Basin-IEVP-CT). Historical data of our previous and the present survey have shown that trypanosomiasis in this particular area is constant and not subject to change over time. In addition, the present study has clarified that T. evansi is endemic in this area due to the interaction of a wide range of factors and features of the host which determine patterns of trypanosomiasis, and its distribution coincides with the distribution ofvectors.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2017.01.003
       
  • Synthesis, physicochemical studies and biological evaluation of
           unimetallic and heterobimetallic complexes of hexadentate dihydrazone
           ligands

    • Authors: Fathy A. El Saied; Mokhles M. Abd-Elzaher; Abdou S. El Tabl; Mohamad M.E. Shakdofa; Anas J. Rasras
      Abstract: Publication date: Available online 7 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Fathy A. El Saied, Mokhles M. Abd-Elzaher, Abdou S. El Tabl, Mohamad M.E. Shakdofa, Anas J. Rasras
      A new coordination unimetallic and heterobimetallic complexes of hexadentate N2O4 donor dihydrazone ligands were prepared by the condensation of 4-formyl antipyrine with adipic dihydrazide and succinic dihydrazide. The ligands (1) and (11) and their complexes thoroughly characterized using various analytical, physical and spectroscopic techniques, which indicate a distorted octahedral geometry around the metal ions. The ESR spectra of solid copper(II) complexes (2–4) and (12–14) showed axial symmetry with g >g⊥>ge, indicating distorted octahedral structure and the presence of the unpaired electron in a d (x2−y2) orbital with significant covalent bond character. The antimicrobial activity results of the metal compounds (2–5), (7), (10), (12–15) and (17) show that, all these complexes exhibit inhibitory moderate to mild effects towards Bacillus subtilis, Escherichia coli and Aspergillus niger.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.005
       
  • Behavioral and neurochemical evaluation of ethanol on olanzapine treated
           methylphenidate induced manic like behaviors in swiss albino mice

    • Authors: Thangavel Tamilselvan; Saiful Alom Siddique; Manikannan Vishnupriya; Ganapathy Sindhu; Elumalai Balamurugan
      Abstract: Publication date: Available online 6 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Thangavel Tamilselvan, Saiful Alom Siddique, Manikannan Vishnupriya, Ganapathy Sindhu, Elumalai Balamurugan
      The present study was aimed to evaluate the effect of olanzapine (OLZ) with ethanol (EtOH) on methylphenidate (MPD) induced mania in Swiss albino mice. The effect of EtOH on OLZ treated MPD induced mice by analysing the behavioral activities in Open field test (OFT), forced swimming test (FST) and the neurotransmitter levels for Dopamine (DA), Norepinephrine (NE), serotonin (5-HT) and γ-Aminobutyric acid (GABA). We assayed by considerably found that repeated administration of MPD (2 mg/kg b.w) produced hyperactivity. MPD induced manic like behavioral was manifested by the increased locomotor activities in open field test (central, peripheral and rearing in 5 min). In forced swim test (FST) increased swimming and decreased immobility time (5 min) in MPD treated mice. In fluorimetric micromethod, MPD administrated mice increased DA, NE, 5-HT levels and decreased the GABA levels in the PFC on 21 days. The results of the present study reported that the OLZ treated mice controlled the mania like behavioral activities and neurotransmitter levels in MPD subjected mice. EtOH enhanced the locomotor activities, immobility time, DA, NE and GABA levels. In addition, EtOH reduced swimming and 5-HT level of the brain. From this result EtOH impairs the OLZ treatment and enhanced the locomotor activity and did not prevent neurotransmitter levels in brain tissue. Further studies will be needed to discover the mechanisms responsible for these findings.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2017.01.001
       
  • In vitro antioxidant activity, total phenolic and flavonoid contents of
           ethanol extract of stem and leaf of Grewia carpinifolia

    • Authors: Olamide E. Adebiyi; Funsho O. Olayemi; Tan Ning-Hua; Zeng Guang-Zhi
      Abstract: Publication date: Available online 4 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Olamide E. Adebiyi, Funsho O. Olayemi, Tan Ning-Hua, Zeng Guang-Zhi
      Free radicals are reactive molecules involved in many physiological processes and have been associated with many diseases, such as cancer, arthritis and liver injury. As a result, there is need to explore substances with free radical scavenging and or antioxidant activity. The present study was designed to evaluate the free radical scavenging activity of ethanol extract of leaf and stem of Grewia carpinifolia using various in vitro models. Ascorbic acid was used as the reference in the study. 1,1-Diphenyl-2-picryl hydroxyl (DPPH) quenching assay, 2,2′-azinobis-3-ethylbenzothiozoline-6-sulfonic acid (ABTS) cation decolorization test, ferric reducing antioxidant power (FRAP) Assay systems were selected for the present experiment. The ability of the extracts to inhibit lipid oxidation was measured using Thiobarbituric Acid Reactive Substances (TBARS) assay. The extracts were used at 0.2, 0.4, 0.6, 0.8 and 1mg/ml concentrations and radical scavenging activity was determined in terms of inhibition percentage. The IC50 (concentration required for 50% inhibition) was also calculated for each radical. The study revealed that Grewia carpinifolia has a high radical scavenging activity in the various radical systems. The total phenolic content was 19.08±1.21mg gallic acid equivalent (GAE)/g extract and 14.85±1.09mg GAE/g extract for the leaf and stem respectively while the flavonoid content was 9.00±0.13 and 13.22±1.53mg quercetin/g extract. The antioxidant activity of Grewia carpinifolia extract may be due to the high level of flavonoids and phenols in the plant.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.003
       
  • Microwave-assisted synthesis, structural activity relationship and
           biological activity of some new quinoxaline Schiff base derivatives as
           highly potent spirochete bactericidal agents

    • Authors: Chandravadivelu Gopi; Vedula Girija Sastry; Magharla Dasaratha Dhanaraju
      Abstract: Publication date: Available online 4 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Chandravadivelu Gopi, Vedula Girija Sastry, Magharla Dasaratha Dhanaraju
      The main aim of this work was to synthesise a new (E)-3-(4-or3-Aminophenylimino) quinoxaline-2(3H)-one oxime Schiff base derivatives and evaluate the anti-leptospiral activity against Leptospira icterohaemorrhagiae. The mentioned derivatives were prepared by performing microwave-assisted condensation reactions of (E)-3-(4-or3-Aminophenyl imino)quinoxaline-2(3H)-one and aromatic aldehydes. The structures of these interesting compounds were characterised by FT-IR, 1H NMR and mass spectroscopy. Furthermore, these compounds were screened for spirocidal activity against Leptospira icterohaemorrhagiae by using in vitro and in vivo method. The anti-leptospiral activity result reveals that most of the compounds were exhibiting considerable activity against Leptospira icterohaemorrhagiae. Compound 6c demonstrated remarkable activity at low concentration against the Leptospira icterohaemorrhagiae as compared to the standard drugs.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.007
       
  • Microwave assisted, solvent-free synthesis and in-vitro antimicrobial
           screening of some novel pyrazolo[3,4-d]pyrimidin-4(5H)-one derivatives

    • Authors: Dipen K. Sureja; Kantilal R. Vadalia
      Abstract: Publication date: Available online 31 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Dipen K. Sureja, Kantilal R. Vadalia


      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.006
       
  • Isolation of chemical constituents fromNonomuraea species: Invitroandin
           silicoevaluation of its antibacterial properties

    • Authors: P. Saravana Kumar; A. Stalin; R. Lakshmisundaram; V. Duraipandiyan; Naif Abdullah Al-Dhabi; P. Yuvaraj; K. Balakrishnan; S. Ignacimuthu
      Abstract: Publication date: Available online 28 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): P. Saravana Kumar, A. Stalin, R. Lakshmisundaram, V. Duraipandiyan, Naif Abdullah Al-Dhabi, P. Yuvaraj, K. Balakrishnan, S. Ignacimuthu
      An actinomycetes strain VAS16 was isolated from the soil collected from the agricultural field of Vengodu. The strain was identified as Nonomuraea species based on morphological, physiological and biochemical characteristics along with 16S rRNA gene sequence analysis. The active extract was purified over silica gel column chromatography. The structure of the active compound was elucidated using FT-IR, EI-MS, 1H NMR and 13C NMR spectra; it was identified as phthalic acid. Phthalic acid obtained from the strain Nonomuraea sp. VAS16 showed significant antibacterial activity against Yersinia enterocolitica and Vibrio parahaemolyticus, with a MIC value of 31.25μg/mL. In silico docking analysis was carried out using GlcN-6-P synthesis as a target. It showed that the compound had minimum binding energy of -6.55KJ/mol and had good affinity. This compound could be probed further for its usefulness as a drug molecule.

      PubDate: 2017-01-01T05:59:30Z
      DOI: 10.1016/j.bjbas.2016.12.004
       
  • Distribution of bacterial contamination in non-sterile pharmaceutical
           materials and assessment of its risk to the health of the final consumers
           quantitatively

    • Authors: Mostafa Essam Eissa
      Pages: 217 - 230
      Abstract: Publication date: Available online 20 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mostafa Essam Eissa
      Bacterial contamination control in pharmaceutical products is a critical aspect in the field of drug manufacturing industry due to the encountered risk to the patients' health and possibly their life. The application of commercial bacterial identification system is crucial to identify the type of contamination and its source to anticipate the impact of bioburden on the products and setting corrective and preventive actions. During the period of one year, random samples from raw materials and final products were tested according to United States Pharmacopeia, and those that showed suspect results for specified microorganisms and/or out-of-specification limits or showed out-of-trend results were subjected to further identification by using miniaturized biochemical identification system after performing Gram stain. From the total bacterial isolates of the investigated products, more than 60% were primarily belonging to Micrococcaceae 16.98% (empty hard gelatin capsules), Enterobacteriaceae 18.86% (vaginal cream applicator, plastic caps for bottles, Sorbitol solution, finished hard gelatin capsule product, topical cream and oral suspension) and Bacillaceae 24.53% (Talc powder, liquid oral preparation and finished hard gelatin capsule product). Gram Positive and Negative samples were 56.60% and 41.51% respectively from the total investigated sample products and materials. Finished pharmaceutical products constituted 53.33% and 68.18% from Gram-positive and Gram-negative microorganisms respectively. An approach to quantitative risk assessment for pharmaceutical products was conducted on selected medicinal items and showed that Enterobacteriaceae followed by Burkholderiaceae contributed by more than 80% to the major hazard that could be delivered to patients through drugs. The applied risk can be used as a milestone for setting goals by pharmaceutical companies to improve the safety of medicinal products microbiologically and to identify the major sources of the risk to work on it in order to deliver safe drugs to the customers.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.08.005
      Issue No: Vol. 5, No. 3 (2016)
       
  • LC/MS characterization of antioxidant flavonoids from Tragia involucrata
           L.

    • Authors: Sulaiman C T; Indira Balachandran
      Pages: 231 - 235
      Abstract: Publication date: Available online 20 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Sulaiman C T, Indira Balachandran
      Chromatographic and spectroscopic methods were developed for the identification of flavonoids with potent radical scavenging activity from Tragia involucrata, an important medicinal plant. The separation consisted of column chromatography and high pressure preparative liquid chromatography. In vitro radical scavenging activity of different fractions was screened by DPPH radical scavenging assay. The ESI MS/MS analysis was employed for the characterization of active fractions. Flavonoids such as iridin, dihexosyl quercetin, quercetin-3-O-rutinoside, rhamnosyl hexosyl methyl quercetin, gentenstein 7-glucoside, orientin, C-(O-caffeoyl-hexosyl)-O-hexoside and tricin 7-O-hexosyl-O-hexoside were identified, for the first time, from T. involucrata.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.06.001
      Issue No: Vol. 5, No. 3 (2016)
       
  • Synthesis and spectroscopic characterisation of novel bioactive molecule
           of 3-(2-substituted)-1H-indol-3-yl)-1-(thiophen-2yl)prop-2-en-1-one
           chalcone derivatives as effective anti-oxidant and anti-microbial agents

    • Authors: Chandravadivelu Gopi; Vedula Girija Sastry; Magharla Dasaratha Dhanaraju
      Pages: 236 - 243
      Abstract: Publication date: Available online 21 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Chandravadivelu Gopi, Vedula Girija Sastry, Magharla Dasaratha Dhanaraju
      The chief purpose of this work was to synthesise and find out the anti-oxidant and anti-microbial activities of novel 3-(2-substituted)-1H-indol-3-yl)-1-(thiophen-2yl)prop-2-en-1-one chalcone derivatives. These derivatives were prepared by performing Claisen–Schmidt condensation reaction of 1-(thiophen-2yl)ethanone and 2 substituted 1H-indole-3-carbaldehyde with constant stirring (approximately for 3 hours) in the presence of ethanol and potassium hydroxide. The newly synthesised compounds' anti-oxidant and anti-microbial activities have been identified by using DPPH radical scavenging assay, zone of inhibition and minimum inhibitory concentration. Most of the prepared compounds had shown excellent anti-oxidant and anti-microbial activities as compared to the standard drugs like Ascorbic acid, Ciprofloxacin and Fluconazole. Among the synthesised compounds, compounds 4e, 4h and 4a showed remarkable activity at low concentration. Therefore, these compounds deserve further research.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.08.004
      Issue No: Vol. 5, No. 3 (2016)
       
  • α-Mangostin Mediated Pharmacological Modulation of Hepatic Carbohydrate
           Metabolism in Diabetes Induced Wistar Rat

    • Authors: Vikas Kumar; Prakash Chandra Bhatt; Gaurav Kaithwas; Mohd Rashid; F.A. Al-abbasi; Jalaluddin A.J. Khan; Firoz Anwar; Amita Verma
      Pages: 255 - 276
      Abstract: Publication date: Available online 20 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Vikas Kumar, Prakash Chandra Bhatt, Gaurav Kaithwas, Mohd Rashid, F.A. Al-abbasi, Jalaluddin A.J. Khan, Firoz Anwar, Amita Verma
      Garcinia mangostana L. (Fruit) has been commonly used as folklore drug in the treatment of various types of diseases. The present experiment was designed to evaluate the potential effect of α-mangostin mediated pharmacological modulation of hepatic carbohydrate metabolism in streptozotocin (STZ) induced diabetic rats. Oral glucose tolerance test (OGTT) was performed in normoglycemic rats. Single intraperitoneal injection of STZ (60 mg/kg, body weight) was used for induction the diabetes in Swiss albino (Wistar strain) rats. The rats were divided into different groups. Blood glucose level, body weight, insulin, glycated hemoglobin and hemoglobin levels were recorded at regular intervals. Biochemical parameters, liver enzymes, lipid profile, antioxidant parameters and inflammatory cytokine mediators were also scrutinized. Histopathology study of kidney, pancreas and liver were performed. The result of OGTT study depicted the better utilization of glucose in experimental rats. STZ induced diabetic rats treated with α-mangostin (25, 50 and 100 mg/kg, p.o.) and glibenclamide depicted the decline in the level of blood glucose; enhanced body weight and showed the better utilization of glucose by different organs. STZ induced diabetic rats treated with α-mangostin illustrated the increased level of plasma insulin, hemoglobin, hexokinase, HDL, total protein, SOD, CAT, GSH and declined level of glycated hemoglobin, fructose-1-6-biphosphatase, glucose-6-Phosphatase, TC, TG, LDL, VLDL, CRE, BUN, SGOT, SGPT, ALP and LPO at effective dose dependent manners. Histological study showed the inflamed blood vessels in diabetic kidney, which was less in α-mangostin treated rats; diabetic pancreatic showed the complete damage of β cells, islets, aciini and producing necrosis, but all damage was less obvious in α-mangostin treating group rats; diabetic liver showed the damage of hepatocytes as well as central vein but was less in treated groups. Considering the above results, α-mangostin shows potential to develop a medicine for diabetes, hyperlipidemia, renal and hepatic protection as combinational or mono-therapy.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.07.001
      Issue No: Vol. 5, No. 3 (2016)
       
  • Characterization and photocatalytic properties of cotton fibers modified
           with ZnO nanoparticles using sol–gel spin coating technique

    • Authors: Mohamed Shaban; Semsem Abdallah; Ahmed Abdel Khalek
      Pages: 277 - 283
      Abstract: Publication date: Available online 20 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed Shaban, Semsem Abdallah, Ahmed Abdel Khalek
      Zinc oxide nanoparticles (ZnO NPs) were prepared using the sol–gel method. Cotton fibers were loaded with ZnO nanoparticles using sol–gel spin coating technique. The prepared ZnO NPs and ZnO-coated cotton were characterized by scanning electron microscope (SEM) and energy dispersive X-ray spectroscopy (EDX). The self-cleaning property of ZnO-coated cotton and the photocatalytic removal of methyl orange dye from the contaminated water and cotton fibers were studied by measuring the optical absorbance after exposure to sunlight and Philips 200W lamp illumination. The results showed that the cotton loaded with ZnO nanoparticles could efficiently decompose 73% of methyl orange dye in the sunlight and 30.7% in the lamp illumination after 12 hours. ZnO nanoparticles decomposed methyl orange dye by 92.7% in the sunlight and 26.4% in the lamp illumination after 7 hours.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.08.003
      Issue No: Vol. 5, No. 3 (2016)
       
  • Anatomical and radiographical studies on the venous drainage of the udder
           

    • Authors: Z.A. Adam; G.A. Ragab; A.S. Awaad; M.G. Tawfiek; M.K.M. Abdel Maksoud
      Pages: 284 - 290
      Abstract: Publication date: Available online 19 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Z.A. Adam, G.A. Ragab, A.S. Awaad, M.G. Tawfiek, M.K.M. Abdel Maksoud
      The present study was achieved to clarify the venous drainage of the udder in twelve healthy Egyptian Baladi goats. Gum-milk latex injection (nine specimens) and radiographic imaging technique (three specimens) were used to demonstrate the course and tributaries of the main veins draining the udder. The obtained results revealed that the udder of goat was drained through three venous circles, one at its base, while the other two were present in the form of one circle at the base of each teat. The basal venous circle was formed by the external pudendal and cranial superficial epigastric veins, as well as the dorsal labial and mammary branch of the ventral perineal vein. While the papillary venous circle was formed mainly by the cranial and caudal lateral sinus branches of the cranial mammary vein of the external pudendal vein. Also, the origin, course, distribution and termination of the cranial superficial epigastric vein were described. The venous architecture reported in this study could serve as a guide for the further surgical interference within the udder of goat.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.08.002
      Issue No: Vol. 5, No. 3 (2016)
       
  • Anatomical and radiographical studies on the arterial supply of the udder
           in goat and their surgical importance

    • Authors: Z.A. Adam; G.A. Ragab; A.S. Awaad; M.G. Tawfiek; M.K.M. Abdel Maksoud
      Pages: 291 - 298
      Abstract: Publication date: Available online 20 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Z.A. Adam, G.A. Ragab, A.S. Awaad, M.G. Tawfiek, M.K.M. Abdel Maksoud
      The present study aimed to show the arterial blood supply of the udder of the Egyptian native breed of goat (Baladi goat) to be used as a guide during mastectomy and other surgical interferences. The study was carried out on the udder of twelve apparently healthy adult female Egyptian Baladi goats. Four goats were used for mastectomy, one specimen was used for radiography and the other specimens were subjected to gum-milk latex injection to clarify the origin, course and distribution of the main arteries supplying the udder. The results revealed that the udder of goat was supplied by the external pudendal artery and dorsal labial and mammary branch of the ventral perineal artery. The course of the external pudendal artery through the inguinal canal before reaching the base of the udder, as well as that of the dorsal labial and mammary branch of the ventral perineal artery in the perineal region, were briefly described to determine the appropriate site for ligation of these vessels before mastectomy. Moreover, the arterial interconnection between the two halves of the udder was emphasized to be highlighted during unilateral mastectomy. Vascular ligation of the main blood vessels supplying the udder on the basis of the anatomical description provided less traumatic surgery and reduced the severity of the blood loss.

      PubDate: 2016-09-24T04:29:07Z
      DOI: 10.1016/j.bjbas.2016.08.001
      Issue No: Vol. 5, No. 3 (2016)
       
  • New travelling wave solutions of the (1 + 1)-dimensional cubic
           nonlinear Schrodinger equation using novel (G′/G)-expansion method

    • Authors: M.G. Hafez
      Pages: 109 - 118
      Abstract: Publication date: Available online 30 May 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): M.G. Hafez
      In this paper, the novel (G′/G)-expansion method is applied to construct exact travelling wave solutions of the cubic nonlinear Schrodinger equation. This technique is straightforward and simple to use, and gives more new general solutions than the other existing methods. Various types of solitary and periodic wave solutions of this equation are derived. The obtained results may be helpful to describe the wave propagation in soliton physics, such as soliton propagation in optical fibers, modulus instability in plasma physics, etc. and provided us the firm mathematical foundation in soliton physics or any varied instances. Furthermore, three-dimensional modules plot of the solutions are also given to visualize the dynamics of the equation.

      PubDate: 2016-06-12T08:11:34Z
      DOI: 10.1016/j.bjbas.2016.03.003
      Issue No: Vol. 5, No. 2 (2016)
       
  • In vitro studies of the antileishmanial activity of the newer
           2-(substitutedphenoxy)-N-[(aryl)methylidene]acetohydrazide analogues

    • Authors: Mohamed Jawed Ahsan; Md Yousuf Ansari; Praveen Kumar; Monika Soni; Sabina Yasmin; Surender Singh Jadav; Ganesh Chandra Sahoo
      Pages: 119 - 125
      Abstract: Publication date: Available online 30 May 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed Jawed Ahsan, Md Yousuf Ansari, Praveen Kumar, Monika Soni, Sabina Yasmin, Surender Singh Jadav, Ganesh Chandra Sahoo
      A series of new 2-(substitutedphenoxy)-N-[(aryl)methylidene]acetohydrazide analogues (8a-n) were synthesized in search of potential therapeutics for leishmaniasis. All the compounds were characterized by infrared (IR), nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry. The compounds were further evaluated for in vitro antileishmanial activity against promastigotes of Leishmania donovani as per the standard protocol reported elsewhere. 2-(2,4-Dichlorophenoxy)-N′-{[4-(morpholin-4-yl)phenyl]methylidene}acetohydrazide (8k) showed the most promising antileishmanial activity with IC50 of 48.10 µM, free from cytotoxicity (>153.08 µM).

      PubDate: 2016-06-12T08:11:34Z
      DOI: 10.1016/j.bjbas.2016.05.002
      Issue No: Vol. 5, No. 2 (2016)
       
  • Physiochemical characterization of taste masking levetiracetam ion
           exchange resinates in the solid state and formulation of stable liquid
           suspension for pediatric use

    • Authors: Sivaneswari S.; Karthikeyan E.; Veena D.; Chandana P.J.; Sai Sumana P.; Subhashree P.; Ramya L.; Rajalakshmi R.; Ashok Kumar C.K.
      Pages: 126 - 133
      Abstract: Publication date: Available online 3 June 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Sivaneswari S., Karthikeyan E., Veena D., Chandana P.J., Sai Sumana P., Subhashree P., Ramya L., Rajalakshmi R., Ashok Kumar C.K.
      In the present work, an attempt has been made to mask the bitter taste of Levetiracetam using various ion-exchange resins such as Amberlite IRP69 and Duolite AP143. The physicochemical characteristics of the drug–resin complex in the solid state were studied. FT-IR studies revealed that there is no interaction between drug and resin. The DSC and XRD studies proved that the drug is in amorphous nature. Using the same concentration of resins, xanthum gum as suspending agent in a liquid dosage form for pediatric use was formulated. Evaluation parameters such as drug content, sedimentation volume, re-dispersibility and viscosity of the prepared suspension were found to be satisfactory. The higher Zeta potential value indicates the stability of the suspension. Suspension prepared with Duolite AP 143 efficiently masks the bitter taste of Levetiracetam compared to Amberlite IRP69. From the in vitro drug release, a formulation with 1:2 ratios of resin has shown the maximum release at the end of 90 minutes. The sustained effect is due to one of the properties of the resin. The release profile follows zero order kinetics. The results obtained in this work show that drug–resin complexes effectively masked the bitter taste of Levetiracetam while liquid formulation provides an easier way to administer and to overcome problems with noncompliance of pediatrics.

      PubDate: 2016-06-12T08:11:34Z
      DOI: 10.1016/j.bjbas.2016.04.004
      Issue No: Vol. 5, No. 2 (2016)
       
  • Hypoglycemic and hypolipidemic effects of ethanolic and aqueous extracts
           from Ziziphus oenoplia (L) Mill on alloxan-induced diabetic rats

    • Authors: Pramod Mourya; Ajay Shukla; Gopal Rai; Santram Lodhi
      Abstract: Publication date: Available online 21 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Pramod Mourya, Ajay Shukla, Gopal Rai, Santram Lodhi
      The objective of present study was to investigate hypoglycemic and hypolipidemic effect of ethanolic and aqueous extracts of Ziziphus oenoplia (L) stem bark against Alloxan induce hyperglycemia in rats. Hyperglycemia was induced by an injection of alloxan monohydrate 150 mg/kg (i.p.). After 72 hr, the rats having Blood Glucose Level (BGL) above 150 mg/dL were selected for the investigation. At two different doses (200 mg/kg and 400 mg/kg b.w.) of aqueous and ethanolic extracts were observed antidiabetic effect for 12 consecutive days. BGL was monitored after 1, 3, 6 and 12 days and compared with Metformin (250 mg/kg). Alpha amylase and alpha glucosidase activity of both extracts were also determined. Phytochemical study revealed the presence of glycosides, flavonoids, alkaloids and terpenoids in ethanol extract and flavonoids, carbohydrates and proteins found in aqueous extract of Z. oenoplia bark. Oral administration of both extracts showed significant (P < 0.05) antihyperglycemic activity in dose dependent manner in alloxan induced diabetic rats. The diabetic rats had significant (P < 0.01) reduction in blood glucose; serum liver enzyme level (AST, ALT, and ALP) and lipid profile were compared with normal rats. Significant effects of aqueous and alcoholic extract in alpha amylase and alpha glucosidase activity were observed in rats. The ethanolic and aqueous extract reveals the reduction in the blood glucose level, inhibition of alpha amylase and alpha glucosidase enzymes which support antidiabetic effect (reduce postprandial glucose levels) of Z. oenoplia and this may be due to presence of flavonoids constituents.

      PubDate: 2016-12-25T05:55:17Z
      DOI: 10.1016/j.bjbas.2016.12.002
       
  • Numerical solution of nonlinear sine–Gordon equation by using the
           modified cubic B-spline differential quadrature method

    • Authors: H.S. Shukla; Mohammad Tamsir
      Abstract: Publication date: Available online 13 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): H.S. Shukla, Mohammad Tamsir
      This paper deals with numerical solution of one dimensional nonlinear sine–Gordon. “Modified cubic B-spline differential quadrature method” is used to solve one dimensional nonlinear sine–Gordon. The method reduces the problem to a system of first order ordinary differential equations (ODEs). The resulting system of ODEs is solved by “an optimal five stage and fourth-order strong stability preserving Runge–Kutta (SSP-RK54) method”. Finally, the method is illustrated and compared with existing methods via numerical examples. It is found that the method not only is quite easy to implement, but also gives better results than the ones already existing in the literature.

      PubDate: 2016-12-17T05:49:22Z
       
  • Culture conditions for the production of thermostable lipase by
           Thermomyces lanuginosus

    • Authors: B. Sreelatha; V. Koteswara Rao; R. Ranjith Kumar; S. Girisham; S.M. Reddy
      Abstract: Publication date: Available online 30 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): B. Sreelatha, V. Koteswara Rao, R. Ranjith Kumar, S. Girisham, S.M. Reddy
      In the present investigation lipase production by three strains of thermophilic Thermomyces lanuginosus (GSLMBKU-10, GSLMBKU-13 and GSLMBKU-14) was carried out in submerged fermentation process. Olive oil and triacetin (0.1%) were added to the basal medium, which stimulated the lipase production. The maximum lipase was produced by GSLMBKU-10 and GSLMBKU-13 in yeast extract starch medium supplemented with triacetin (0.1%). The optimum pH was recorded at 6.0, 6.5 and 7.0 by GSLMBKU-10, GSLMBKU-13 and GSLMBKU-14 respectively. T. lanuginosus GSLMBKU-10 strains failed to produce lipase at pH 8.0. The optimum temperature for lipase production was observed at 45 °C by GSLMBKU-14 and GSLMBKU-10, while that for GSLMBKU-13 was at 50 °C. The marginal temperature ranged from 45 °C to 50 °C for both lipase production and vegetative growth by the three strains of T. lanuginosus under study. In conclusion, the GSLMBKU-13 strain was comparatively superior in the production of lipase than the other two strains under investigation.

      PubDate: 2016-12-03T03:50:56Z
      DOI: 10.1016/j.bjbas.2016.11.010
       
  • Antioxidant and antibacterial activities of various extracts of Inula
           cuspidata C.B. Clarke stem

    • Authors: Sarvesh Kumar Paliwal; Bhawana Sati; Samriti Faujdar; Swapnil Sharma
      Abstract: Publication date: Available online 23 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Sarvesh Kumar Paliwal, Bhawana Sati, Samriti Faujdar, Swapnil Sharma
      The objective of the present study includes estimation of total phenolic and total flavonoid contents and evaluation of antioxidant and antibacterial activities of various extracts of Inula cuspidata stem. I. cuspidata belongs to family Compositae; it is an erect shrub, distributed in western Himalaya, usually found growing on steep rocky or precipitous ground. Total phenolic and flavonoid contents were estimated by Folin–Ciocalteu and aluminum chloride method. Antioxidant activity was performed by four methods: DPPH (1,1-diphenyl-2-picryl hydrazyl radical), ferrous chelating activity, reducing power and nitric oxide scavenging activity. These extracts were screened for antibacterial studies using macro-dilution method. Total phenolic and flavonoid contents were found to be highest in methanol extract (69.44 ± 1.12 mg GAE/g, 12.45 ± 0.67 mg QE/g) followed by chloroform (33.53 ± 0.88 mg GAE/g, 1.27 ± 0.51 mg QE/g) and n-hexane (12.25 ± 1.03 mg GAE/g, 0.08 ± 0.43 mg QE/g) extracts. Methanol extract of I. cuspidata exhibited potent antioxidant activity in all the antioxidant assays followed by chloroform and n-hexane extracts. IC50 values of methanol, chloroform and n-hexane extract were found to be 43.35 ± 0.58 µg/mL, 298.08 ± 0.62 µg/mL, 1989.24 ± 0.71 µg/mL for DPPH, 396.63 ± 0.73 µg/mL, 915.29 ± 0.81 µg/mL, 1180.56 ± 0.88 µg/mL for ferrous chelating and 594.68 ± 0.99 µg/mL, 930.55 ± 1.03 µg/mL, 1959.26 ± 1.25 µg/mL for nitric oxide scavenging assays. A strong correlation was found between total phenolic, flavonoid and 1/IC50 values obtained by different antioxidant assays. The correlation coefficient (R) value obtained was more than 0.9 which exhibits a strong correlation. All the extracts showed significant antibacterial activities against Gram positive bacterial strains with minimum inhibitory concentration (MIC) values ranging from 187.5 to 750 µg/mL and moderate to weak inhibition against Gram negative bacteria with MIC values ranging from 750 to 3000 µg/mL. The present study proves the in vitro anti-oxidant and antibacterial activities of different extracts of I. cuspidata stem.

      PubDate: 2016-11-26T01:34:54Z
      DOI: 10.1016/j.bjbas.2016.10.003
       
  • Chemical composition, lethality and antifungal activities of the extracts
           of leaf of thaumatococus daniellii against foodborne fungi

    • Authors: Oluwagbenga Adeogun; Adedotun Adekunle; Anofi Ashafa
      Abstract: Publication date: Available online 17 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Oluwagbenga Adeogun, Adedotun Adekunle, Anofi Ashafa
      The consumers' interest in natural preservatives seemed to have increased because of the apathy and negative effect of synthetic preservatives. This study explored the use of Thaumatococcus daniellii leaves as potential preservatives against fungi responsible for the spoilage of orange juice and corn jell-o. The leaves of the plant were extracted with different solvents: acetone, aqueous, ethanol and hexane and assayed against test fungi using disc diffusion method. The minimum inhibitory and fungicidal concentrations were determined. The qualitative and quantitative phytochemical analyses of leaves of the plants was carried out, the most active extract of the fresh and dried leaves were assayed via GC-MS for the essential oils and HPLC fingerprinting was used to determine the phytochemical constituents of the most active extracts. The toxicity test of the extracts against Brine shrimp was carried out after 24 hours of exposure. The ethanol extracts of the plants were the most active based on the antifungal assay. The toxicity test revealed that the extracts of the plants were non-toxic on the Brine Shrimps at LD50 (592.95µg/ml and 281.12µg/ml for aqueous and ethanol extracts). The qualitative phytochemical screening revealed the presence of alkaloid, tannin, saponins, flavonoids, steroids and terpenoids in the leaf of the plant. The quantitative phytochemical analysis of the most active extract in the plants revealed alkaloids with the highest contents of 107.48mg/100g. The GC-MS analyses of the fresh leaves of the plants revealed the presence of isodecane at 15.16%. The GC-MS analyses of the dried leaves revealed 1, 2, 3 Trimethylbenzene in T. danielli with the highest percentage of 15.48%. The HPLC analysis revealed the presence various phytochemical constituents in the dried leaves of the plant. This study has been able to ascertain the potency of Thaumatococcus daniellii leaves on fungi responsible for spoilage of sweet Citrus sinensis (orange) juice and Corn Jell-O (‘Eko’) which contribute to continuous drive towards the use and total acceptance of natural antimicrobials.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.006
       
  • Iterative method for approximate solution of fuzzy integro-differential
           equations

    • Authors: Mahmood Otadi; Maryam Mosleh
      Abstract: Publication date: Available online 17 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mahmood Otadi, Maryam Mosleh
      In this paper, we interpret a nonlinear fuzzy Fredholm integro-differential equations by using the strongly generalized differentiability concept. Based on the parametric form of a fuzzy number, a fuzzy integro-differential equation converts to two systems of integro-differential equations in the crisp case. Also, we use the parametric form of fuzzy number, and an iterative approach for obtaining approximate solution for a class of nonlinear fuzzy Fredholm integro-differential equation of the second kind is proposed. This paper presents a method based on Newton-Cotes methods with positive coefficient. Then we obtain approximate solution of the nonlinear fuzzy integro-differential equations by an iterative approach.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.008
       
  • Insilco Study on the Toxicity of Anti-Cancer Compounds Tested against
           MOLT-4 And P388 Cell Lines Using GA-MLR Technique

    • Authors: David Ebuka Arthur; Adamu Uzairu; Paul Mamza; Stephen Eyije Abechi; Gideon Shallangwa
      Abstract: Publication date: Available online 17 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): David Ebuka Arthur, Adamu Uzairu, Paul Mamza, Stephen Eyije Abechi, Gideon Shallangwa
      The research entails the development of two models that can be used to predict the toxicity of compounds suspected of having anti-leukemia activity, the two models ones for MOLT-4 and the other for P388 cell lines were developed by carefully selecting 5 descriptors in each case from a pool of 4,900 molecular descriptors using GA-MLR method. The ability of the models to predict chemicals that were not used in the preparation set was evaluated by validating the models internally [Q2 CV MOLT-4=0.644 and Q2 CV (P388) =0.641] and externally [R2 pred (P388) = 0.662 and R2 pred (MOLT-4) =0.679], other criteria such as r2 m, R2 p, k and k' were also determined and were found to support R2 pred results of the models. The effect of every descriptor in the model were dictated by calculating their individual mean effect to (pLC50) the toxicities of the compounds. SpMax7_Bhm (1.697) and RDF145u (-4.300) influenced the models the most, while in MOLT-4 the descriptors with the least effect was n-isopropyl (0.0343) and for P388 is 1.162. the models were further validated by subjecting them to y-randomization which finally confirmed the robustness of the models developed.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.003
       
  • Rhusaucheri boiss an omani herbal medicine: identification and in-vitro
           antioxidant and antibacterial potentials of its leaves extracts

    • Authors: Vandita Singh; Fatima Al-Malki; Mohammad Sadat Ali; Philip Fletcher; Nejib Guizani; Omima Al-Saidi; Rahma Al-Hanaai; Rawan Al-bahri; Safiya Al-Ghdani; Syed Sikander Hasan; Hakikulla Hamidulla Shah
      Abstract: Publication date: Available online 17 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Vandita Singh, Fatima Al-Malki, Mohammad Sadat Ali, Philip Fletcher, Nejib Guizani, Omima Al-Saidi, Rahma Al-Hanaai, Rawan Al-bahri, Safiya Al-Ghdani, Syed Sikander Hasan, Hakikulla Hamidulla Shah
      Rhusaucheri Boiss is a popular Omani herbal medicinal plant used as an antiseptic, astringent and homeostatic. In this study we evaluated, the antioxidant and antibacterial potential of R. Boiss leaves using an in-vitro model. Three green solvents i.e. water ethanol and aqueous glycerol was employed to access the extraction of polyphenols and flavonoids. We found the highest polyphenols and flavonoids extraction for aqueous glycerol extracts The antioxidant capacity was assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical reducing abilities of the three liquid crude extracts (LCEs) and was recorded to be high in water and aqueous glycerol LCEs (91 & 83.1%) respectively. The screening of antibacterial potential was gauged against gram positive bacterial strains namely Staphylococcus aureus (ATCC® 29213™), Staphylococcus aureus (ATCC® 25923™) and Enterococcus faecalis (ATCC® 29212™) as well as one gram negative strain Escherichia coli. The three LCEs were found to be fairly active against the microbial strains tested. Further, we recorded the scanning electron microscopic (SEM) images of the leaves of R. Boiss leaves to underpin the botanical characters of the leaves so that any future studies of this plant will have sound basis.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.002
       
  • Efficient synthesis of a novel series of indeno fused
           pyrido[2,3-d]pyrimidines using β-cyclodextrin-propyl sulfonic acid as an
           eco-friendly catalyst

    • Authors: Prasanna Nithiya Sudhan; Majid Ghashang; Syed Sheik Mansoor
      Abstract: Publication date: Available online 16 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Prasanna Nithiya Sudhan, Majid Ghashang, Syed Sheik Mansoor
      A simple and facile synthesis of 5-aryl-5,11-dihydro-1H-indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine-2,4,6-trione derivatives was accomplished by the one-pot condensation of aromatic aldehydes, 1,3-indandione and 6-amino uracil under solvent-free conditions in the presence of the catalyst, β-cyclodextrin-propyl sulfonic acid (β-CD-PSA). This method has the advantages of high yield, clean reaction, simple methodology, and short reaction time. The catalyst could be recycled and reused four times without significant loss of activity.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.004
       
  • Preconcentration and determination of titanium in tap water, geological
           and sunscreen cream samples by CPE-FAAS method

    • Authors: Ardeshir Shokrollahi; Masoud Gohari
      Abstract: Publication date: Available online 16 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Ardeshir Shokrollahi, Masoud Gohari
      In the presented research, a cloud-point extraction method has been used for the preconcentration of trace amounts of Ti(IV) after complex formation with cupferron (phenyl-nitroso-hydroxylamine ammonium) using Triton X-114 as the surfactant. The chemical variables affecting the phase separation and the signal of flame atomic absorption spectrometry were optimized. At pH = 3.0, preconcentration of the analyte content sample in the presence of 0.07% (w/v) Triton X-114 and 8.6 × 10−5 M cupferron enabled the detection limit (3Sb/m) of 0.01 µg/mL Ti(IV) and linear range 0.03–3.00 µg/mL to be achieved. The enhancement factor and preconcentration factor were 37 and 30 respectively. The relative standard deviation by repeated assays of six separate solution of 0.67 µg/mL Ti(IV) was also obtained 3.90%. The proposed method was applied to the determination of Ti(IV) in tap water, sand, feldspar and sunscreen cream.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.007
       
  • Corrigendum to “LPS-induced oxidative inflammation and hyperlipidemia in
           male rats: The protective role of Origanum majorana extract” [Beni-Suef
           Univ J Basic Appl Sci 4 (4) (2015) 291–298]

    • Authors: Mayssaa M. Wahby; Galila Yacout; Kamal Kandeel; Doaa Awad
      Abstract: Publication date: Available online 15 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mayssaa M. Wahby, Galila Yacout, Kamal Kandeel, Doaa Awad


      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.009
       
  • Repeatability estimates of egg weight and egg-shell weight under various
           production periods for Bovan Nera Black laying chicken

    • Authors: Sylvia Alwell John-Jaja; Utibeabasi Hilary Udoh; Samuel Chukwujindu Nwokolo
      Abstract: Publication date: Available online 10 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Sylvia Alwell John-Jaja, Utibeabasi Hilary Udoh, Samuel Chukwujindu Nwokolo
      The present research was designed to examine the repeatability estimates of egg weight and egg shell weight of exotic layers at 25, 51, 72 weeks and overall ages of the bird. For this purpose, thirty birds were selected from the flock of layers in the Babcock University Teaching and Research Farm. A total of thirty (30) eggs were collected daily from the birds continuously for five (5) days of egg production, at each age 25, 51 and 72 weeks. The total number of eggs collected at each age was 150 and 450 for the total of three age periods. Data were collected on egg production traits for egg weight and egg shell weight. The mean values of the egg quality traits revealed an apparent increase for egg weight 55.02–63.29 g and egg shell weight 6.36–7.81 g with a corresponding mean combined data of bird of 60.17 g for egg weight and 7.26 g for egg shell weight. A significant positive genetic correlation was obtained among traits with linear regression equations at different age groups. General linear model procedure of statistical analytical system was used to obtain the variance components for the estimation of repeatability. High repeatability estimates were obtained when the age variance was included in the computation and low to moderate estimates were registered when the age variance was excluded from the computation. Since repeatability estimates from various production periods of egg weight and egg shell weight were low to moderate, these traits can be improved by mass selection there culminating in egg production with optimal quality.

      PubDate: 2016-11-12T01:26:10Z
      DOI: 10.1016/j.bjbas.2016.11.001
       
  • Removal of hexavalent chromium from aqueous solutions by adsorption on
           modified groundnut hull

    • Authors: Samson O. Owalude; Adedibu C. Tella
      Abstract: Publication date: Available online 10 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Samson O. Owalude, Adedibu C. Tella
      There is an emerging serious threat to the environment from indiscriminate release of heavy metals into the wastewaters and soil from human industrial practices. In this study therefore, the uptake of hexavalent chromium, being among the major pollutants from our industries, by modified and unmodified groundnut hull was investigated. The effects of different conditions of contact time, adsorbate concentration, solution pH, and temperature, on sorption process were studied. The adsorbent materials were characterized by Fourier Transform Infrared Spectroscopy (FT-IR). Analysis of the surface morphology by Scanning Electron Microscopy (SEM) revealed a change in morphology upon chromium adsorption. The adsorption process of Cr(VI) ions onto both the unmodified groundnut hull (UGS) and the modified groundnut hull (MGS) is in good agreement with the Langmuir adsorption isotherm and follows the pseudo-second-order kinetic model. According to the equilibrium studies, chromium(VI) ions are better adsorbed by modified groundnut hull.

      PubDate: 2016-11-12T01:26:10Z
      DOI: 10.1016/j.bjbas.2016.11.005
       
  • Approximation of analytic functions in adaptive environment

    • Authors: Saumya Ranjan Jena; Kumudini Meher; Arjun kumar Paul
      Abstract: Publication date: Available online 2 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Saumya Ranjan Jena, Kumudini Meher, Arjun kumar Paul
      In this paper, a mixed quadrature rule of degree of precision seven is formed for analytic functions by taking two constituent rules each of degree of precision five. Here the integral of analytic function is converted to real definite integrals with the help of double transformations. Then the mixed quadrature rule is tested in adaptive environment and it is obviously superior to that of Gauss-Legendre three-point rule.

      PubDate: 2016-11-05T01:19:26Z
      DOI: 10.1016/j.bjbas.2016.10.001
       
  • Morphological study of some taxa of Ranunculaceae Juss in Egypt (anatomy
           and pollen grains)

    • Authors: Mohamed A. Salim; Al-Safa H. Mohamed; Mohamed E. Tantawy
      Abstract: Publication date: Available online 29 October 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed A. Salim, Al-Safa H. Mohamed, Mohamed E. Tantawy
      Ranunculaceae is a large angiospermic family (43 genera and 2346 species). Seven taxa were subjected in the present study representing six genera. Stem anatomy, flower anatomy, lamina epidermal characters as well as the pollen morphology were carried out according to traditional taxonomic methods using LM and SEM. The specific target of the present study is to contribute knowledge to Ranunculaceae from different perspectives. The obtained microcharacters of stem, leaf and flowers are considered diagnostic at the generic and specific levels (e.g., stem outline, types of cortex, internal appearance of stem, leaf types, perianth vascularization and presence of nectary scales). The pollen characters of the studied taxa are considered highly diagnostic at the generic and specific levels especially pollen class (trizonocolpate, pantocolpate and pantoporate) and pollen sculpture (aculeate, verrucate-aculeate, aculeate-faveolate and scabrate-verrucate). The obtained data facilitate the construction of artificial keys to delimitation between the studied taxa.

      PubDate: 2016-11-05T01:19:26Z
      DOI: 10.1016/j.bjbas.2016.10.002
       
  • Effect of hydrothermal curing on hydration characteristics of
           metakaolin–CKD pastes at different temperatures in a closed system

    • Authors: Mohamed R. Shatat; Gomaa A.M. Ali; Gamal A. Gouda
      Abstract: Publication date: Available online 27 October 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed R. Shatat, Gomaa A.M. Ali, Gamal A. Gouda
      Well–sealed stainless steel capsule was used as a hydrothermal system to study the pozzolanic activity and hydration characteristics of metakaolin (MK)–cement kiln dust (CKD) at different temperatures (40, 80, 120 and 150 °C) up to 24 hours hydrothermal curing. The physico-chemical properties of hydrothermally treated MK-CKD pastes were studied by measuring the compressive strength, porosity and bulk density of the hardened pastes as hydraulic properties. The hydration properties of the pastes were studied by measuring free lime and chemically-combined water contents. The phase composition and crystalline structure of the obtained hydrates were studied using X–ray diffraction (XRD) and differential thermal analysis (DTA). The results indicated that, the higher activity is shown at 80 °C especially at the later age of hydrothermal curing. Moreover, the mix containing 75 % MK and 25 % CKD by mass possessed the higher characteristics during the later age of hydrothermal curing and at all curing temperatures.

      PubDate: 2016-10-28T22:53:03Z
      DOI: 10.1016/j.bjbas.2016.09.002
       
  • Extended modified cubic B-spline algorithm for nonlinear Burgers's
           equation

    • Authors: Mohammad Tamsir; Neeraj Dhiman Vineet Srivastava
      Abstract: Publication date: Available online 19 September 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohammad Tamsir, Neeraj Dhiman, Vineet K. Srivastava
      In this paper, an extended modified cubic B-Spline differential quadrature method is proposed to approximate the solution of the nonlinear Burgers's equation. The proposed method is used in space and a five-stage and four order strong stability-preserving time-stepping Runge–Kutta (SSP-RK54) method is used in time. The accuracy and efficiency of the method is illustrated by considering four numerical problems. The numerical results of the method are compared with some existing methods and it was found that the proposed numerical method produces acceptable results and even more accurate results in comparison with some existing methods. The stability analysis of the scheme is also carried out and was found to be unconditionally stable.

      PubDate: 2016-09-24T04:29:07Z
       
  • Synthesis, ADME studies, toxicity estimation, and exploration of molecular
           recognition of thiophene based chalcones towards monoamine oxidase-A and B
           

    • Authors: Bijo Mathew; Jerad Suresh; Githa Elizabeth Mathew; Abitha Haridas; Geethu Suresh; P. Sabreena
      Abstract: Publication date: Available online 13 April 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Bijo Mathew, Jerad Suresh, Githa Elizabeth Mathew, Abitha Haridas, Geethu Suresh, P. Sabreena
      The validity of the chalcone scaffold for the design of inhibitors of monoamine oxidase had previously been reported. A series of thiophene based chalcones were synthesized by the reaction between 2-acetyl thiophene and substituted aromatic aldehyde according to the Claisen-Schmidt condensation. The structures of the synthesized compounds were ascertained by spectral analysis. Drug-likeness of the titled derivatives was done by blood–brain barrier, Lipinski's rule of 5 and in silico toxicity prediction. Using molecular docking study, we proposed that the synthesized thiophene scaffolds can successfully dock into the inhibitor binding pockets of monoamine oxidase B than A. In this series, 3-[4- (dimethyl amino) phenyl]-1-(thiophen-2-yl) prop-2-en-1-one (Td) showed a docking score of −8.46 kcal/mol and calculated inhibition constant of about 0.64 µM towards the active site of MAO-B.

      PubDate: 2016-04-30T11:00:48Z
      DOI: 10.1016/j.bjbas.2015.06.003
       
  • Design of experiment based validated stability indicating rp-HPLC method
           of temozolomide in bulk and pharmaceutical dosage forms

    • Authors: Anam Khan; Syed Sarim Imam; Mohd Aqil; Yasmin Sultana; Asgar Ali; Khalid Khan
      Abstract: Publication date: Available online 8 April 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Anam Khan, Syed Sarim Imam, Mohd. Aqil, Yasmin Sultana, Asgar Ali, Khalid Khan
      A simple, precise, stability indicating RP-HPLC method was developed and validated for determination of Temozolomide (TMZ) in bulk sample and nanostructured lipid carriers. A Box-Behnken statistical design with three factors and three levels was employed to optimize the chromatographic conditions. The separation was achieved using solvent system combination using methanol: water (30:70) with acetic acid (0.25%). The developed method was validated for linearity, precision, accuracy, limit of detection and limit of quantitation, and robustness in accordance with the ICH guidelines. Further degradation study of TMZ in different stress conditions was studied. The method was found linear with regression co-efficient of 0.999 over a wide range of 10-100 µg/mL. All the validation parameters were found to be within the acceptance range. The developed method was successfully applied to estimate the amount of TMZ in pharmaceutical formulations.

      PubDate: 2016-04-09T03:04:20Z
      DOI: 10.1016/j.bjbas.2015.11.011
       
 
 
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