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  Subjects -> ENGINEERING (Total: 2270 journals)
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ENGINEERING (1199 journals)                  1 2 3 4 5 6 | Last

Showing 1 - 200 of 1205 Journals sorted alphabetically
3 Biotech     Open Access   (Followers: 7)
3D Research     Hybrid Journal   (Followers: 19)
AAPG Bulletin     Full-text available via subscription   (Followers: 5)
AASRI Procedia     Open Access   (Followers: 15)
Abstract and Applied Analysis     Open Access   (Followers: 3)
Aceh International Journal of Science and Technology     Open Access   (Followers: 2)
ACS Nano     Full-text available via subscription   (Followers: 215)
Acta Geotechnica     Hybrid Journal   (Followers: 6)
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 5)
Acta Polytechnica : Journal of Advanced Engineering     Open Access   (Followers: 2)
Acta Scientiarum. Technology     Open Access   (Followers: 3)
Acta Universitatis Cibiniensis. Technical Series     Open Access  
Active and Passive Electronic Components     Open Access   (Followers: 7)
Adaptive Behavior     Hybrid Journal   (Followers: 10)
Adıyaman Üniversitesi Mühendislik Bilimleri Dergisi     Open Access  
Adsorption     Hybrid Journal   (Followers: 4)
Advanced Engineering Forum     Full-text available via subscription   (Followers: 4)
Advanced Science     Open Access   (Followers: 4)
Advanced Science Focus     Free   (Followers: 3)
Advanced Science Letters     Full-text available via subscription   (Followers: 5)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 7)
Advanced Synthesis & Catalysis     Hybrid Journal   (Followers: 17)
Advances in Artificial Neural Systems     Open Access   (Followers: 4)
Advances in Calculus of Variations     Hybrid Journal   (Followers: 2)
Advances in Catalysis     Full-text available via subscription   (Followers: 5)
Advances in Complex Systems     Hybrid Journal   (Followers: 7)
Advances in Engineering Software     Hybrid Journal   (Followers: 25)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 14)
Advances in Fuzzy Systems     Open Access   (Followers: 5)
Advances in Geosciences (ADGEO)     Open Access   (Followers: 9)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 19)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 23)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 8)
Advances in Natural Sciences: Nanoscience and Nanotechnology     Open Access   (Followers: 28)
Advances in Operations Research     Open Access   (Followers: 11)
Advances in OptoElectronics     Open Access   (Followers: 5)
Advances in Physics Theories and Applications     Open Access   (Followers: 12)
Advances in Polymer Science     Hybrid Journal   (Followers: 40)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Remote Sensing     Open Access   (Followers: 35)
Advances in Science and Research (ASR)     Open Access   (Followers: 6)
Aerobiologia     Hybrid Journal   (Followers: 1)
African Journal of Science, Technology, Innovation and Development     Hybrid Journal   (Followers: 4)
AIChE Journal     Hybrid Journal   (Followers: 28)
Ain Shams Engineering Journal     Open Access   (Followers: 5)
Akademik Platform Mühendislik ve Fen Bilimleri Dergisi     Open Access  
Alexandria Engineering Journal     Open Access   (Followers: 1)
AMB Express     Open Access   (Followers: 1)
American Journal of Applied Sciences     Open Access   (Followers: 27)
American Journal of Engineering and Applied Sciences     Open Access   (Followers: 11)
American Journal of Engineering Education     Open Access   (Followers: 9)
American Journal of Environmental Engineering     Open Access   (Followers: 16)
American Journal of Industrial and Business Management     Open Access   (Followers: 23)
Analele Universitatii Ovidius Constanta - Seria Chimie     Open Access  
Annals of Combinatorics     Hybrid Journal   (Followers: 3)
Annals of Pure and Applied Logic     Open Access   (Followers: 2)
Annals of Regional Science     Hybrid Journal   (Followers: 7)
Annals of Science     Hybrid Journal   (Followers: 7)
Applicable Algebra in Engineering, Communication and Computing     Hybrid Journal   (Followers: 2)
Applicable Analysis: An International Journal     Hybrid Journal   (Followers: 1)
Applied Catalysis A: General     Hybrid Journal   (Followers: 6)
Applied Catalysis B: Environmental     Hybrid Journal   (Followers: 8)
Applied Clay Science     Hybrid Journal   (Followers: 4)
Applied Computational Intelligence and Soft Computing     Open Access   (Followers: 12)
Applied Magnetic Resonance     Hybrid Journal   (Followers: 3)
Applied Nanoscience     Open Access   (Followers: 7)
Applied Network Science     Open Access  
Applied Numerical Mathematics     Hybrid Journal   (Followers: 5)
Applied Physics Research     Open Access   (Followers: 3)
Applied Sciences     Open Access   (Followers: 2)
Applied Spatial Analysis and Policy     Hybrid Journal   (Followers: 4)
Arabian Journal for Science and Engineering     Hybrid Journal   (Followers: 5)
Archives of Computational Methods in Engineering     Hybrid Journal   (Followers: 4)
Archives of Foundry Engineering     Open Access  
Archives of Thermodynamics     Open Access   (Followers: 7)
Arkiv för Matematik     Hybrid Journal   (Followers: 1)
ASEE Prism     Full-text available via subscription   (Followers: 2)
Asian Engineering Review     Open Access  
Asian Journal of Applied Science and Engineering     Open Access   (Followers: 1)
Asian Journal of Applied Sciences     Open Access   (Followers: 2)
Asian Journal of Biotechnology     Open Access   (Followers: 7)
Asian Journal of Control     Hybrid Journal  
Asian Journal of Current Engineering & Maths     Open Access  
Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 8)
Assembly Automation     Hybrid Journal   (Followers: 2)
at - Automatisierungstechnik     Hybrid Journal   (Followers: 1)
ATZagenda     Hybrid Journal  
ATZextra worldwide     Hybrid Journal  
Australasian Physical & Engineering Sciences in Medicine     Hybrid Journal   (Followers: 1)
Australian Journal of Multi-Disciplinary Engineering     Full-text available via subscription   (Followers: 2)
Autonomous Mental Development, IEEE Transactions on     Hybrid Journal   (Followers: 7)
Avances en Ciencias e Ingeniería     Open Access  
Balkan Region Conference on Engineering and Business Education     Open Access   (Followers: 1)
Bangladesh Journal of Scientific and Industrial Research     Open Access  
Basin Research     Hybrid Journal   (Followers: 3)
Batteries     Open Access   (Followers: 3)
Bautechnik     Hybrid Journal   (Followers: 1)
Bell Labs Technical Journal     Hybrid Journal   (Followers: 23)
Beni-Suef University Journal of Basic and Applied Sciences     Open Access   (Followers: 3)
BER : Manufacturing Survey : Full Survey     Full-text available via subscription   (Followers: 2)
BER : Motor Trade Survey     Full-text available via subscription   (Followers: 1)
BER : Retail Sector Survey     Full-text available via subscription   (Followers: 2)
BER : Retail Survey : Full Survey     Full-text available via subscription   (Followers: 2)
BER : Survey of Business Conditions in Manufacturing : An Executive Summary     Full-text available via subscription   (Followers: 3)
BER : Survey of Business Conditions in Retail : An Executive Summary     Full-text available via subscription   (Followers: 3)
Bharatiya Vaigyanik evam Audyogik Anusandhan Patrika (BVAAP)     Open Access   (Followers: 1)
Biofuels Engineering     Open Access  
Biointerphases     Open Access   (Followers: 1)
Biomaterials Science     Full-text available via subscription   (Followers: 9)
Biomedical Engineering     Hybrid Journal   (Followers: 16)
Biomedical Engineering and Computational Biology     Open Access   (Followers: 13)
Biomedical Engineering Letters     Hybrid Journal   (Followers: 5)
Biomedical Engineering, IEEE Reviews in     Full-text available via subscription   (Followers: 16)
Biomedical Engineering, IEEE Transactions on     Hybrid Journal   (Followers: 31)
Biomedical Engineering: Applications, Basis and Communications     Hybrid Journal   (Followers: 5)
Biomedical Microdevices     Hybrid Journal   (Followers: 8)
Biomedical Science and Engineering     Open Access   (Followers: 3)
Biomedizinische Technik - Biomedical Engineering     Hybrid Journal  
Biomicrofluidics     Open Access   (Followers: 4)
BioNanoMaterials     Hybrid Journal   (Followers: 1)
Biotechnology Progress     Hybrid Journal   (Followers: 39)
Boletin Cientifico Tecnico INIMET     Open Access  
Botswana Journal of Technology     Full-text available via subscription  
Boundary Value Problems     Open Access   (Followers: 1)
Brazilian Journal of Science and Technology     Open Access   (Followers: 2)
Broadcasting, IEEE Transactions on     Hybrid Journal   (Followers: 10)
Bulletin of Canadian Petroleum Geology     Full-text available via subscription   (Followers: 14)
Bulletin of Engineering Geology and the Environment     Hybrid Journal   (Followers: 3)
Bulletin of the Crimean Astrophysical Observatory     Hybrid Journal  
Cahiers, Droit, Sciences et Technologies     Open Access  
Calphad     Hybrid Journal  
Canadian Geotechnical Journal     Full-text available via subscription   (Followers: 13)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 40)
Case Studies in Engineering Failure Analysis     Open Access   (Followers: 7)
Case Studies in Thermal Engineering     Open Access   (Followers: 3)
Catalysis Communications     Hybrid Journal   (Followers: 6)
Catalysis Letters     Hybrid Journal   (Followers: 2)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 8)
Catalysis Science and Technology     Free   (Followers: 6)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 3)
Catalysis Today     Hybrid Journal   (Followers: 5)
CEAS Space Journal     Hybrid Journal  
Cellular and Molecular Neurobiology     Hybrid Journal   (Followers: 3)
Central European Journal of Engineering     Hybrid Journal   (Followers: 1)
CFD Letters     Open Access   (Followers: 6)
Chaos : An Interdisciplinary Journal of Nonlinear Science     Hybrid Journal   (Followers: 2)
Chaos, Solitons & Fractals     Hybrid Journal   (Followers: 3)
Chinese Journal of Catalysis     Full-text available via subscription   (Followers: 2)
Chinese Journal of Engineering     Open Access   (Followers: 2)
Chinese Science Bulletin     Open Access   (Followers: 1)
Ciencia e Ingenieria Neogranadina     Open Access  
Ciencia en su PC     Open Access   (Followers: 1)
Ciencias Holguin     Open Access   (Followers: 1)
CienciaUAT     Open Access  
Cientifica     Open Access  
CIRP Annals - Manufacturing Technology     Full-text available via subscription   (Followers: 11)
CIRP Journal of Manufacturing Science and Technology     Full-text available via subscription   (Followers: 14)
City, Culture and Society     Hybrid Journal   (Followers: 21)
Clay Minerals     Full-text available via subscription   (Followers: 9)
Clean Air Journal     Full-text available via subscription   (Followers: 2)
Coal Science and Technology     Full-text available via subscription   (Followers: 3)
Coastal Engineering     Hybrid Journal   (Followers: 11)
Coastal Engineering Journal     Hybrid Journal   (Followers: 4)
Coatings     Open Access   (Followers: 2)
Cogent Engineering     Open Access   (Followers: 2)
Cognitive Computation     Hybrid Journal   (Followers: 4)
Color Research & Application     Hybrid Journal   (Followers: 1)
COMBINATORICA     Hybrid Journal  
Combustion Theory and Modelling     Hybrid Journal   (Followers: 13)
Combustion, Explosion, and Shock Waves     Hybrid Journal   (Followers: 13)
Communications Engineer     Hybrid Journal   (Followers: 1)
Communications in Numerical Methods in Engineering     Hybrid Journal   (Followers: 2)
Components, Packaging and Manufacturing Technology, IEEE Transactions on     Hybrid Journal   (Followers: 23)
Composite Interfaces     Hybrid Journal   (Followers: 6)
Composite Structures     Hybrid Journal   (Followers: 252)
Composites Part A : Applied Science and Manufacturing     Hybrid Journal   (Followers: 176)
Composites Part B : Engineering     Hybrid Journal   (Followers: 223)
Composites Science and Technology     Hybrid Journal   (Followers: 165)
Comptes Rendus Mécanique     Full-text available via subscription   (Followers: 2)
Computation     Open Access  
Computational Geosciences     Hybrid Journal   (Followers: 12)
Computational Optimization and Applications     Hybrid Journal   (Followers: 7)
Computational Science and Discovery     Full-text available via subscription   (Followers: 2)
Computer Applications in Engineering Education     Hybrid Journal   (Followers: 6)
Computer Science and Engineering     Open Access   (Followers: 17)
Computers & Geosciences     Hybrid Journal   (Followers: 25)
Computers & Mathematics with Applications     Full-text available via subscription   (Followers: 5)
Computers and Electronics in Agriculture     Hybrid Journal   (Followers: 4)
Computers and Geotechnics     Hybrid Journal   (Followers: 8)
Computing and Visualization in Science     Hybrid Journal   (Followers: 6)
Computing in Science & Engineering     Full-text available via subscription   (Followers: 25)
Conciencia Tecnologica     Open Access  
Concurrent Engineering     Hybrid Journal   (Followers: 3)
Continuum Mechanics and Thermodynamics     Hybrid Journal   (Followers: 6)
Control and Dynamic Systems     Full-text available via subscription   (Followers: 8)
Control Engineering Practice     Hybrid Journal   (Followers: 41)
Control Theory and Informatics     Open Access   (Followers: 7)
Corrosion Science     Hybrid Journal   (Followers: 24)
CT&F Ciencia, Tecnologia y Futuro     Open Access  
CTheory     Open Access  

        1 2 3 4 5 6 | Last

Journal Cover Beni-Suef University Journal of Basic and Applied Sciences
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2314-8535
   Published by Elsevier Homepage  [3031 journals]
  • Fermentation of lignocellulose ingredients in vivo and in vitro via using
           faecal and caecal inoculums of monogastric animals (swine/turkeys)

    • Authors: Ibrahim M.I. Youssef; Josef Kamphues
      Abstract: Publication date: Available online 18 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Ibrahim M.I. Youssef, Josef Kamphues
      Three experiments were performed to evaluate the digestibility and fermentation rates of two types of lignocellulose products that can be used in diets of pigs and turkeys. Experiment I: In vitro dry matter digestibility studies using Daisy system were conducted by using fecal or excreta fluid of swine/turkeys as a source of inoculums. The feedstuffs used as substrates were commercial swine or turkey diet, lignocellulose A and B. The dry matter digestibility was found to be about 75%, 28%, and < 5% for swine/turkey diet, lignocellulose A and B, respectively. Moreover, the inoculums were incubated with the same substrates for 24h using gas measuring technique. It was found that the product A was fermented better than B and resulted in higher amounts of acetic, propionic and lactic acids. Experiment II: Six swine were divided into 2 groups; the control group was fed on a commercial swine diet, whereas the experimental one was offered a commercial swine diet containing 2.0% lignocellulose A. The digestibility rates of dry matter, organic matter, and crude fiber of both diets were found to be nearly identical. Experiment III: At the end of study, the animals were slaughtered and the caecum contents of swine and turkeys were used as inoculums and incubated with the same tested substrates for 24h using gas production technique. As observed with fecal/excreta inocula, lignocellulose A resulted in greater amounts of gases, volatile fatty acids and lactate compared to product B. In conclusions, lignocellulose A can be used as alternative source of fiber to maintain the health and function of digestive tract. Furthermore, the use of feces/excreta liquor provides a valid and proper estimate of digestibility or fermentation of feeds. These results provide further guide that this procedure would be an effective and practical means of approximating the digestibility of diets.

      PubDate: 2017-05-18T11:43:38Z
      DOI: 10.1016/j.bjbas.2017.05.006
       
  • Applying decision-making techniques to civil engineering projects

    • Authors: Fam F. Abdel-malak; Usama H. Issa; Yehia H. Miky; Emad A. Osman
      Abstract: Publication date: Available online 13 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Fam F. Abdel-malak, Usama H. Issa, Yehia H. Miky, Emad A. Osman
      Multi-Criteria Decision-Making (MCDM) techniques are found to be useful tools in project managers' hands to overcome Decision-Making (DM) problems in Civil Engineering Projects (CEPs). The main contribution of this paper includes selecting and studying the popular MCDM techniques that uses different and wide ranges of data types in CEPs. A detailed study including advantages and pitfalls of using the Analytic Hierarchy Process (AHP) and Fuzzy Technique for Order of Preference by Similarity to Ideal Solution (Fuzzy TOPSIS) is introduced. Those two techniques are selected for the purpose of forming a package that covers most available data types in CEPs. The results indicated that AHP has a structure which simplifies complicated problems, while Fuzzy TOPSIS uses the advantages of linguistic variables to solve the issue of undocumented data and ill-defined problems. Furthermore, AHP is a simple technique that depends on pairwise comparisons of factors and natural attributes, beside it is preferable for widely spread hierarchies. On the other hand, Fuzzy TOPSIS needs more information but works well for the one-tier decision tree as well as it shows more flexibility to work in fuzzy environments. The two techniques have the facility to be integrated and combined in a new module to support most of the decisions required in CEPs.

      PubDate: 2017-05-18T11:43:38Z
      DOI: 10.1016/j.bjbas.2017.05.004
       
  • Earth-Sheltered Buildings in Hot-arid Climates: Design Guidelines

    • Authors: Heba Hassan; Daisuke Sumiyoshi
      Abstract: Publication date: Available online 12 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Heba Hassan, Daisuke Sumiyoshi
      One of the most effective techniques to meet the tradeoff between thermal comfort and low energy consumption in hot-arid climates is Earth sheltering. This paper reports the results of research series which aim to measure the suitability of applying the Earth sheltering technique at hot-arid climates, in Egypt as a case study. The research tested 164 experts’ responses about their attitude towards Earth-sheltered buildings and obtained their recommendations and preferences about the architectural and urban design guidelines. On the other hand, basement’s thermal performance was tested, through simulation and measurements to reach the calibration process. Moreover, measuring the balance between the thermal comfort, and energy savings through a parametric optimization analysis. The tested design variables were 25 window/wall ratio percentages, 23 orientation angles, and five cities location templates; Ismailia, Sharm-El-Shiekh, Al Minya, Marsa-Matrouh and Al Kharga. The research results present site-specific guidelines, through several topics; architectural design guidelines, site selection and urban planning guidelines, for architects and urban planners regarding the application of this technique for residential buildings.

      PubDate: 2017-05-13T11:39:22Z
      DOI: 10.1016/j.bjbas.2017.05.005
       
  • A Quantitative Review and Classification of Empirical Models for
           Predicting Global Solar Radiation in West Africa

    • Authors: Samuel Chukwujindu Nwokolo; Julie C. Ogbulezie
      Abstract: Publication date: Available online 10 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Samuel Chukwujindu Nwokolo, Julie C. Ogbulezie
      The knowledge of the global solar radiation is of particular significance in reliable evaluation of the solar energy potential in a given locality. However, ground measurement of global solar radiation (GSR) is not available in most locations in West Africa. During the past 36 years in order to estimate GSR on the horizontal surface on both daily and monthly mean daily basis, several empirical models have been developed for numerous locations in West Africa. As a result, various input parameters have been utilized and numerous functional forms employed. In this study aimed at classifying and reviewing the empirical models employed for estimating GSR in West Africa, the empirical models so far utilized were classified into six main categories and presented based on the input parameters employed. The models were further reclassified into numerous main sub-classes (groups) and finally presented according to their developing year. On the whole, 356 empirical models and 68 functional forms were reported in literature for estimating GSR in West Africa. The authors equally compared the empirical and soft computing models for estimating GSR in West Africa and across the globe and observed that the soft computer models yielded better. Thus, this review would provide solar energy researchers in terms of identifying the input parameters and functional forms widely employed up till now as well as recognizing their importance for estimating GSR in several locations and need to adopt soft computing methods particularly promising as an alternative approach for estimate GSR with high precision in West Africa.

      PubDate: 2017-05-13T11:39:22Z
      DOI: 10.1016/j.bjbas.2017.05.001
       
  • Molluscicidal activity of Bacillus thuringiensis strains against
           Biomphilaria alexandrina snails

    • Authors: Amany M. Abd El-Ghany; Nesreen M. Abd El-Ghany
      Abstract: Publication date: Available online 9 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Amany M. Abd El-Ghany, Nesreen M. Abd El-Ghany
      Schistosomiasis is a parasitic disease transmitted to man and different warm blooded animals by means of snails. Great effort has been made to control the transmission of the disease by many strategies. Consequently, the utilization of particular molluscicides is viewed as a standout amongst the best measures for molluscs control. Recently, microbial pathogen used as non-traditional molluscicides which have attracted significant research attention due to the increasing, worldwide development of resistance to chemical molluscicides in molluscs populations. The present work aimed to study the molluscicidal impacts of eleven isolates of Bacillus thuringiensis which were isolated from soils of six Egyptian governorates toward Biomphalaria alexandrina snails. Results showed that, B. thuringiensis provides an effective biological control agent against B. alexandrina snails. Out of the tested isolates, four isolates; Qalyubia, Asyut 1, Qena and North Sinai 2 isolates show high-level molluscicidal activity. The obtained results indicated that LC50 and LC90 values were ranged between 133.27 - 457.74 mg/mL and 270.32 - 781.05 mg/mL, respectively. The most noteworthy molluscicidal impact was displayed by Qalyubia isolate which isolated from Qalyubia governorate with mortality rate extended from 20-100% at five treatment concentrations of 100-500 mg/mL. The LC50 and LC90 values for Qalyubia isolate were 133.27 mg/mL and 270.32 mg/mL, respectively.

      PubDate: 2017-05-13T11:39:22Z
      DOI: 10.1016/j.bjbas.2017.05.003
       
  • Ulva lactuca hydroethanolic extract suppresses experimental arthritis via
           its anti-inflammatory and antioxidant activities

    • Authors: Osama M. Ahmed; Hanan A.Soliman; Basant Mahmoud; Randa R Gheryany
      Abstract: Publication date: Available online 4 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Osama M. Ahmed, Hanan A.Soliman, Basant Mahmoud, Randa R Gheryany
      This study was designed to evaluate the effect of Ulva lactuca hydroethanolic extract on rheumatoid arthritis in male Wistar rats. Rheumatoid arthritis was induced in rats by subcutaneous injection of 200µl Freund’s complete adjuvant into a footpad of the right hind leg of male rats at two consecutive days. Arthritic rats were orally treated with Ulva lactuca hydroethanolic extract at dose level of 100 mg /kg b.wt /day for 1, 2 and 3 weeks and were compared with corresponding arthritic control at the same periods. The increased right hind paw circumference at tarsal pad, deleteriously affected ankle joint histological architecture, articular inflammatory cell infiltration and focal necrosis in arthritic rats were counteracted by hydroethanolic extract treatment at the three tested periods. Elevated leukocytes count in arthritic rats connected with changes of spleen and thymus histological architecture, extramedullary megakaryocytes, lymphoblasts activation and mitotic figures were significantly improved by Ulva lactuca hydroethanolic extract treatment at the three tested peroids. The elevated rheumatoid factor (RF), prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-α), interleukin-17 (IL-17) and interleukin-1beta (IL-1β) levels and the lowered interleukin-4 (IL-4) level in arthritic rats were markedly ameliorated as a result of Ulva lactuca administration. The lowered glutathione level and glutathione peroxidase, glutathione reductase and superoxide dismutase activities as well as the elevated lipid peroxides level in serum of arthritic rats were potentially alleviated as a result of Ulva lactuca treatment. In conclusion, Ulva lactuca could have anti- arthritic efficacies which may be mediated via its anti-inflammatory and anti-oxidant potentials.

      PubDate: 2017-05-08T11:27:52Z
      DOI: 10.1016/j.bjbas.2017.04.013
       
  • Hepatoprotective activity of methanolic extracts of Lactuca runcinata DC
           and Gyrocarpus asiaticus Willd.

    • Authors: Lakshmi Kanta Kanthal; K. Satyavathi; P. Bhojaraju; Manna Prabal Kumar
      Abstract: Publication date: Available online 4 May 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Lakshmi Kanta Kanthal, K. Satyavathi, P. Bhojaraju, Manna Prabal Kumar


      PubDate: 2017-05-08T11:27:52Z
      DOI: 10.1016/j.bjbas.2017.05.002
       
  • Molecular Docking Analysis and Antidiabetic activity of Rifabutin against
           STZ-NA induced diabetes in albino wistar rats

    • Authors: Danish Ahmed; Mohd. Ibrahim Khan; Gaurav Kaithwas; Subhadeep Roy; Swetlana Gautam; Manjari Singh; Uma Devi; Rajnsih Yadav; Jitendra Rawat; Shubhini Saraf
      Abstract: Publication date: Available online 25 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Danish Ahmed, Mohd. Ibrahim Khan, Gaurav Kaithwas, Subhadeep Roy, Swetlana Gautam, Manjari Singh, Uma Devi, Rajnsih Yadav, Jitendra Rawat, Shubhini Saraf
      Computer Aided Drug Design (CADD) molecular docking program used in this study and as a result Rifabutin was retrieved as structurally similar drug molecule to Lixisenatide (A widely used GLP-1 agonist). To afford beneficial reason in-vitro study conducted which too provides a favourable mark for prospective inhibition of α-glucosidase and α-amylase enzyme and thereby evaluated for its antidiabetic potential against Streptozotocin (STZ) and Nicotinamide (NA) induced diabetes in albino wistar rats. Rifabutin demonstrated significant efficacy towards restoring the blood glucose, insulin and distorted lipid profile in the animals treated with STZ-NA. Rifabutin also regulated the inflammatory (Nitric Oxide) and oxidative stress (TBARs, SOD, Catalase, GSH and protein carbonyl) markers in the pancreatic tissue of the STZ-NA treated animals. When scrutinized on the grounds electrocardiographic and heart rate variability (HRV) changes, Rifabutin decreased the heart rate, without much affecting the QRS, QT and QTc interval. Rifabutin was also evident to be less hepatotoxic in comparison to the standard metformin, providing an added advantage as an anti-diabetic agent. The study concluded that the low dose of rifabutin can favourably regulate of the blood glucose and other biochemical paradigms in comparison to high dose of rifabutin.
      Graphical abstract image

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.010
       
  • Heavy metal and Potential Ecological Risk Assessment in sedimentscollected
           from Poombuhar to Karaikal Coast of Tamilnadu using Energy dispersive
           X-ray fluorescence (EDXRF) technique

    • Authors: E. Devanesan; M. Suresh Gandhi; M. Selvapandian; G. Senthilkumar; R. Ravisankar
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): E. Devanesan, M. Suresh Gandhi, M. Selvapandian, G. Senthilkumar, R. Ravisankar
      Heavy metal concentrations in coastal sediments from Poombuhar to Karaikal of South East Coast of Tamilnadu were conducted to evaluate the level of contamination. The metal concentrations were analyzed in sediment samples using Energy dispersive X-ray fluorescence technique. The determined mean metal concentration is in the order of Ca > Ti > K > Al > Fe > Mg > Zn > Ni > Cr > V > Mn > Co The heavy metals contamination in sediments is assessed using pollution indices like Contamination factor (Cf), Contamination Degree (Cd), Modified Degree of Contamination (mCd) and potential contamination index (Cp). The environmental risks of the heavy metals in sediments assessed by the potential ecological risk factor. From the analysis, sediments are polluted by Ti, V, Cr, Mn, Ca and Pb due to anthropogenic activites (fishermen boat activites) in the study area. The results of this study would provide a useful aid for sustainable marine management in the region.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.011
       
  • Impact of Generic Antimalarial or Phyllanthus Amarus and Vitamin
           Co-Administration on Antioxidant Status of Experimental Mice Infested With
           Plasmodium Berghei

    • Authors: Matthew Obaineh Ojezele; Emuesiri Goodies Moke; Innocent Onyesom
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Matthew Obaineh Ojezele, Emuesiri Goodies Moke, Innocent Onyesom
      Oxidative stress is a key factor in malaria pathogenesis, particularly, malaria induced anaemia and pathological changes in some organs in the body. This research aimed at investigating the effect of Phyllanthus amarus seed extract (PASE), chloroquine (CLQ), and artesunate (ATS) used alone and co-administered with vitamin A, B, C, or E on oxidative stress in Plasmodium berghei-infected mice. A total of eighty (80) adult albino male mice infected with P. berghei (NK 65 strain) were randomly allotted to 16 treatment groups, mice in another group (17th group) were uninfected; n=5. Of the treatment groups, fifteen were administered sole generic antimalarials/PASE and combined vitamins A, B, C or E orally for 5 days. Biochemical assay for glutathione peroxidase (GPx), and glutathione reductase (GR) were carried out on the serum. Assay for glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), catalase (CA), and malondialdehyde (MDA) levels were carried out on homogenised liver and brain. Treatment with PASE, CLQ and ATS combined with vitamin A, B, or E respectively, demonstrated significant increase in the serum levels of GPx and GR concentration. Treatment with PASE/ATS alone and in combination with vitamin A, B, C, and E significantly increased the liver GPX, SOD, and CA levels with significant decrease in liver MDA levels. Treatment with PASE/CLQ alone and in combination with vitamin A, B, C, and E significantly increased the brain GPX, GR and SOD levels with significant decrease in brain MDA levels. PASE showed enhanced antioxidant capacity in plasmodiasis solely or combined with vitamins A, B and E. Furthermore the co-administration of generic agent like artesunate with vitamins A, B, and E enhanced the antimalarial activity and treatment outcome as shown by the antioxidant effects. However, co-administration with vitamin C may be counter-productive.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.008
       
  • Backing of 2-(Diethylamino)-N-(2, 6-dimethylphenyl) – acetamide with
           Molecular, Electronic and Docking Studies

    • Authors: J. Deva Anban; Sayantan Pradhan; C. James
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): J. Deva Anban, Sayantan Pradhan, C. James
      In this study, the anaesthetic compound 2-(diethylamino)-N-(2, 6-dimethylphenyl)-acetamide (DEAL) was optimized with the B3LYP- 6-311+ G (d, p) density functional theory method. Hyper conjugative interactions revealed the bioactivity of the molecule by natural bond orbital analysis. The current–potential curves were noted at well-defined scan rates by cyclic voltammetry. The solvation free energy was calculated by applying the solvation model on density. Molecular docking simulations were carried out to understand the pharmacokinetic behaviour of the drug. Besides, total energy levels of HOMO-LUMO orbitals, Mulliken atomic charges, natural population analysis and polarizability properties of the molecule were calculated. We found that the secondary amide increases the stability of this molecule. The π→π∗ interactions increase the biological activity of the compound, leading to a very high stabilization.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.012
       
  • Hepatotoxicity and Genotoxicity of Gasoline Fumes in Albino Rats

    • Authors: Folarin O. Owagboriaye; Gabriel A. Dedeke; Joseph S. Ashidi; A.A. Aladesida; Wasiu E. Olooto
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Folarin O. Owagboriaye, Gabriel A. Dedeke, Joseph S. Ashidi, A.A. Aladesida, Wasiu E. Olooto
      Toxic effects of gasoline fumes have been reported, but evidence of its hepatotoxicity and genotoxicity are rare. Therefore, this study assesses hepatotoxicity and genotoxicity of gasoline fumes on forty Albino rats randomly assigned to five experimental treatments (T) with eight rats per treatment (T1, T2, T3, T4 and T5). T1(Control) was housed in a section of experimental animal house free from gasoline fumes while T2, T3, T4 and T5 were exposed to gasoline fumes in exposure chambers for one, three, five and nine hours daily respectively for twelve weeks. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and histopathological examination of the liver tissues were used as diagnostic markers to assess liver dysfunction. Genotoxicity test was conducted on the lung tissues using randomly amplified polymorphic DNA fingerprinting polymerase chain reaction (RAPD PCR) technique. Significant increase (p<0.05) in the level of ALT, AST and ALP for T2, T3, T4 and T5 compared to T1 were recorded. Photomicrograph examination of the liver sections of T1 showed hepatic tissue with normal liver cell architecture while that of T2, T3, T4 and T5 revealed degenerative changes in the ultrastructural integrity of the hepatic cells. Genotoxicity test revealed DNA bands at a reducing intensity from T1 to T5. Dendrogram showed DNA damage in the lungs of T3, T4 and T5 were closely similar and the genotoxic impact was more in T3. Frequent exposure to gasoline fumes was observed to induce hepatoxicity and genotoxicity, hence impairing the normal liver function and gene structure.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.007
       
  • Taurine Dietary Supplementation Attenuates Brain, Thyroid, Testicular
           Disturbances and Oxidative Stress in Streptozotocin-Induced Diabetes
           Mellitus in Male Rats

    • Authors: N.A. Mohamed; H.S. Abdel Gawad
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): N.A. Mohamed, H.S. Abdel Gawad
      The metabolic dysregulation associated with DM causes secondary pathophysiological changes in multiple organ systems. This work aimed to study the effect of taurine supplementation on brain, thyroid, testicular disturbances and oxidative stress in diabetic rats. Male Wistar rats were randomly divided into four groups (Group 1, control; group 2, diabetic; group 3, diabetic+taurine; group 4, taurine). The results illustrated that the dietary taurine intake was effective in lowering the elevated plasma levels of AChE, GnRH, TSH, FSH and LH in diabetic rats compared to untreated ones (P<0.05), whereas TRH, T3, T4 and testosterone, were significantly increased. Taurine improved the sperm characteristics in diabetic rats as indicated by sperm counts and motility. The data revealed that taurine intake was able to reverse the oxidative effect of diabetes on the antioxidant status of brain, thyroid and testis in diabetic rats. The taurine treated group also showed a significant improvement in the degenerative changes of the seminiferous tubules and spermatogenesis. In summary, it was suggested that taurine may have a regulatory effect on diabetes-induced changes in the gonadal-hormone levels by inhibiting hypothalamic–pituitary–gonadal axis and thyroid dysfunctions in the diabetic male rats.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.006
       
  • Internal Transcribed Sequence (ITS) ofHalocafeteria seosinensis
           (Bicosoecids)

    • Authors: Rathinam Raja; Shanmugam Hemaiswarya; Venkatesan ganesan; Isabel S Carvalho
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Rathinam Raja, Shanmugam Hemaiswarya, Venkatesan ganesan, Isabel S Carvalho
      The aim of the current study was to characterize and identify the smaller subunit (18S) and Internal Transcribed Spacer (ITS) regions, ITS1 and ITS2 (ITS1-5.8S-ITS2) of Halocafeteria seosinensis (Bicosoecida). Halocafeteria was isolated from the salterns of Morocco and maintained using standard techniques. The ITS1 and ITS2 are non-conserved regions which were amplified using universal primers, ITS1 and ITS4. The purified PCR products were directly sequenced by Sanger dideoxy sequencing technology and submitted to GenBank. For the construction of cladogram, closely related 18S rDNA sequences obtained from GenBank were multiple aligned using MEGA 6 software and the cladogram constructed by maximum likelihood method with 10000 bootstrapping (BP) repetitions. The phylogenetic relationship among the other related stramenopiles were also studied. The molecular characterization by PCR of 18S genes was useful in confirming the taxonomic identity of a biflagellated H. seosinensis gen. et sp. nov. The ITS1-5.8S-ITS2 region of Halocafeteria is the one to be characterized for the very first time in the whole family of Bicosoecida. Due to discrepancy in placing Halocafeteria in Bicosoecida family, there is need in the characterization of ITS region sequences of stramenopiles and to use multigenes (such as 18S and ITS regions) for reconstructing the evolution tree.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.009
       
  • Ultrasound assisted one Pot expeditious synthesis of new
           pyrido[2,3-d]pyrimidine analogues using mild and inexpensive
           4-dimethylaminopyridine (DMAP) catalyst

    • Authors: Ajmal R. Bhat; Gowhar A. Naikoo; Israr Ul Hassan; Rajendra S. Dongra
      Abstract: Publication date: Available online 19 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Ajmal R. Bhat, Gowhar A. Naikoo, Israr Ul Hassan, Rajendra S. Dongra
      The one-pot three-component reaction for the synthesis of pyrido[2,3-d]pyrimidine derivatives has been reported via initial Knoevenagel, subsequent addition and final heterocyclization of substituted aromatic aldehydes, cyanoacetamide and 6-aminouracil in N,N- dimethylformamide (DMF) solvent using 4-dimethylaminopyridine (DMAP) as new organocatalyst under ultrasound irradiation. The results showed that a series of aromatic aldehydes were successfully used to prepare the targeted pyrido[2,3-d]pyrimidine derivatives with good to excellent yields (81-93%) and there is no major effect on the yield of product by electron donating/withdrawing substituents. Short reaction time, environment friendly procedure, excellent yields, inexpensive and readily available catalyst are the advantages of this procedure. All synthesized compounds were characterized by IR, 1HNMR, 13CNMR and mass spectral data.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.005
       
  • Molecular characterization of Newcastle disease virus (genotype VII) from
           broiler chickens in Egypt

    • Authors: Samar S. Ewies; Ahmed Ali; Sabry M. Tamam; Hanafy M. Madbouly
      Abstract: Publication date: Available online 19 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Samar S. Ewies, Ahmed Ali, Sabry M. Tamam, Hanafy M. Madbouly
      Newcastle disease (ND) outbreaks have been occurred in the Egyptian poultry causing high mortalities with severe economic losses. Samples were collected from 3 to 4weeks-old broiler chickens suffering from high mortalities respiratory and/or nervous signs, located at Beni-Suef, Minia, Fayoum, Ismailia and Menofia governorates and Postmortem examination showed hemorrhages at both proventricular glands and cecal tonsils. The samples were subjected to virus isolation trials by inoculation of the processed samples in the allantoic sac of 9-day-old specific pathogen free eggs (SPF). Hemagglutinating activity was tested by hemagglutination test and the isolated viruses were molecularly characterized by RT-PCR targeting the partial F-gene of NDV. Partial F gene sequence analysis showed that the isolated NDV strains belong to genotype VII with the characteristic amino acid sequences of the F0 protein proteolytic cleavage site motifs (112RRQKRF117) for the velogenic NDV strains. No significant differences in both nucleotide and amino acid sequences were observed among different examined strains. The vNDV isolates in this study were identical to each other and they were similar to strains isolated from Egypt during 2012–2014 with minor genetic variation. This study indicated that though intensive ND vaccination programs using LaSota like strains, the vNDV strains of genotype VII are still circulating in the field causing significant economic losses. The genetic variation between the used vaccine strains and the circulating NDV viruses may explain the inability of the currently used vaccines to protect chicken against vNDV genotype VII. Further studies are needed to screen the protection of the currently used vaccines against recently isolated vNDV strains.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.004
       
  • Design and combinatorial library generation of 1H 1,4 benzodiazepine 2,5
           diones as photosystem-II inhibitors: A public QSAR approach

    • Authors: Purusottam Banjare; Jagadish Singh; Partha Pratim Roy
      Abstract: Publication date: Available online 18 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Purusottam Banjare, Jagadish Singh, Partha Pratim Roy
      Exponential rise in the population around the word increased the demand of food grains/crops with limited expansion of the agricultural land. To meet the demand, generation of new herbicidal agents is of primary need for the manufacturing firm. In silico tool like QSAR is one of the regularly used in designing newer compounds along with wet experiment. Photosystem-II (PS-II) regarded as one of the major target for the herbicidal agents. With this aim in the present study a series of 1H, 1,4 benzodiazepine 2,5-dione analogues as herbicidal (PS-II inhibitors) agents were subjected to QSAR analysis using 2D PaDEL descriptors (open source). Two different splitting techniques namely, kennard stone based and k-means clustering splitting were used to divide the whole data set and GFA based on MAE criteria was used a statistical method to develop a model to investigate the physicochemical and structural requirement of potential PS-II inhibitors. All the models are statistically robust both internally and externally (Q2: 0.540–0.693, R2 pred: 0.722–0.810). The activity is mostly affected by polarizabilities, electro negativities as well as substituents at the phenyl ring. Based on the results, a library of compounds was generated using SmiLib v2.0 tool (open source) and better predicted inside applicability domain compounds were identified by applying three different applicability domain (AD) approaches. Therefore the developed public QSAR models may be helpful for the scientific community for the further research.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.003
       
  • Isolation and molecular characterization of actinomycetes with
           antimicrobial and mosquito larvicidal properties

    • Authors: Pathalam Ganesan; Rajendran Host Antony David; Appadurai Daniel Reegan; Munusamy Rajiv Gandhi; Michael Gabriel Paulraj; Savarimuthu Ignacimuthu; Naif Abdullah Al-Dhabi
      Abstract: Publication date: Available online 11 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Pathalam Ganesan, Rajendran Host Antony David, Appadurai Daniel Reegan, Munusamy Rajiv Gandhi, Michael Gabriel Paulraj, Savarimuthu Ignacimuthu, Naif Abdullah Al-Dhabi
      The present study aimed to isolate actinomycetes from soil samples collected from Western Ghats regions, Tamil Nadu, India. Totally 400 actinomycetes isolates were isolated, of which 161 (40.2%) showed antimicrobial activity in preliminary screening. Secondary screening yielded 27 active isolates; twelve of them showed good antimicrobial and larvicidal activities. Five isolates namely S12-4, S12-17, S12-8, DPS-14 and FMS-20 presented 98%, 93%, 87%, 82%, and 80% larvicidal activity against Cx. quinquefasciatus; very low larvicidal activity was observed against Ae. aegypti. S12-4 showed 100% larval mortality against An. stephensi. RAPD results showed highest similarity between DPS-122 and KFS-24 (0.89246). The polymorphic index observed in the primers ranged from 0.286 (OPA-09) to 0.07 (OPC-18). The results suggest that Western Ghats regions may be a good natural source for isolation of actinobacteria and thereby for discovering novel molecules with antimicrobial and mosquito larvicidal properties.

      PubDate: 2017-04-18T15:13:33Z
      DOI: 10.1016/j.bjbas.2017.04.002
       
  • Histomocytological and Histochemical Features of the Adrenal Gland of
           Adult Egyptian native breeds of Chicken (Gallus gallus domesticus)

    • Authors: U.K. Moawad; M.H. Randa
      Abstract: Publication date: Available online 6 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): U.K. Moawad, M.H. Randa
      Background Avian adrenal gland is one of the most important endocrine glands as it regulates several vital physiological functions.Removal of such gland leads to death of bird. Objective the present investigation aims to illustrate morphological, histocytological and histochemical features of adrenal gland of Adult Egyptian native breeds of Chicken (Gallus gallus domesticus) by means of gross anatomy, light and transmission electron microscope. Materials and Methods Thirty chickens of 6 months old were collected from Beni-Suef province, Egypt. Immediately after scarifying the birds, right and left adrenals were subjected to histomorphological, histochemical and ultrastructural examinations. Results Grossly, the adrenal glands were situated cranio-medially to the kidneys with yellowish color. Histologically, they were ensheathed with thin collagenous connective tissue capsule containing many blood vessels and associated with numerous autonomic ganglia. The parenchyma was composed of mixture of cortical and medullary tissues as well as numerous blood sinusoids. The cortical tissues were demarcated in two distinct zones; subcapsular and inner. The cells of subcapsular cortical zone (SCZ) contained more lipid droplets and less mitochondria than the inner cortical cells do. Two types of chromaffin cells were distinguished; epinephrine (E-) and norepinephrine (NE-) producing cells. The former contained spherical moderate electron-dense secretory granules. The latter contained abundant pleomorphic intensely electron-dense secretory granules. Conclusion Higher cortical tissues on the expense of medullary ones may be the need for increased production of adrenal cortical hormones (glucocorticoids and mineralocorticoids) in the chicken that lives in areas which water conservation is important

      PubDate: 2017-04-11T15:07:55Z
      DOI: 10.1016/j.bjbas.2017.04.001
       
  • Haematology of Clarias gariepinus Exposed to Microcystin-LR

    • Authors: Isibor Patrick Omoregie
      Abstract: Publication date: Available online 1 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Isibor Patrick Omoregie
      A static bioassay experiment was conducted by exposing Clarias gariepinus to 200µg/L and 400µ/L of MC-LR solutions for 14 days and 28 days to assess the haematological impacts such as estimation of red blood cells, white blood cell and thrombocytes, haemoglobin percentage, haematocrit, and percentage changes. A dramatic reduction was observed in the RBCs in both experimental cases after 28 days; which can be attributed to haemolysis. Result showed significant impact of MC-LR on RBCs counts on duration (28 days) basis; regardless of the concentrations. The PCV after 28 days was significantly lower than that observed after 14 days, which was also significantly lower than that observed in the control set-up. The concentrations; particularly 400µg/L MC-LR exerted significant stress on the fish. A general temporal increase was recorded in the total count of WBCs in both experimental cases. Results showed that MC-LR; particularly 400µg/L caused significant haematological disruptions in the C. gariepinus, especially after 28 days of exposure i.e. 400 µg/L (28 days) > 400 µg/L (14 days) > 200 µg/L (28 days) > 200 µg/L (14 days). Due to the fact that natural aquatic ecosystems affected with algal bloom contain concentrations of MC-LR higher than the experimented levels, aquatic biota in affected water bodies are liable to suffer worse consequences than those observed in this experiment. This necessitates proactive measures on susceptible water bodies in order to forestall liable debilitating effects on the aquatic biota.

      PubDate: 2017-04-04T15:02:47Z
      DOI: 10.1016/j.bjbas.2017.03.005
       
  • Polymeric nanoparticles based topical gel of poorly soluble drug:
           Formulation, ex-vivo and in-vivo evaluation

    • Authors: Mohammed Elmowafy; Ahmed Samy; Abdelaziz E. Abdelaziz; Khaled Shalaby; Ayman Salama; Mohamed A. Raslan; Mohamed A. Abdelgawad
      Abstract: Publication date: Available online 30 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohammed Elmowafy, Ahmed Samy, Abdelaziz E. Abdelaziz, Khaled Shalaby, Ayman Salama, Mohamed A. Raslan, Mohamed A. Abdelgawad
      The study was conducted to evaluate the potential application of nanocapsules and nanospheres as topical drug delivery systems for indomethacin (as model drug). Both were prepared by nanoprecipitation using poly (ɛ-caprolactone) and hydroxypropyl β-cyclodextrin polymers and evaluated for morphology, particle size, zeta potential, EE% and in vitro drug release then incorporated in methylcellulose and Carbopol 940 gel bases and evaluated for in vitro release. The selected formulations and market product were evaluated for ex vivo human skin permeation and anti-inflammatory and analgesic activities by paw edema and hot plate methods respectively. Results showed that nanocapsules had slight higher EE% and larger particle sizes than nanospheres. In vitro release and zeta potential were nearly similar. Methylcellulose exhibited higher in vitro release than Carbopol 940 after 3h (except NS2). Ex vivo skin permeation studies showed significant higher cumulative amount of IND (and flux) from NC1/MC and NS1/MC (1573.06±14.23 µg/cm2 and 1452.24±23.18 µg/cm2 respectively) than market product. They also showed enhancement ratio and permeability coefficient rate of ∼ 1.5 and ∼ 2 respectively. NC1/MC proved to be significantly higher pharmacodynamic effects than market product. All results showed that NC1/MC could provide a promising formula as a topical delivery of indomethacin.

      PubDate: 2017-04-04T15:02:47Z
      DOI: 10.1016/j.bjbas.2017.03.004
       
  • Morphological, Histochemical and Computed Tomography on the Vomeronasal
           Organ (Jacobson's Organ) of Egyptian Native Breeds of Goats (Capra hircus)
           

    • Authors: Usama Kamal Moawad; Ashraf Sayed Awaad; BahaaEldeen Ali Abedellaah
      Abstract: Publication date: Available online 24 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Usama Kamal Moawad, Ashraf Sayed Awaad, BahaaEldeen Ali Abedellaah
      Background The vomeronasal organ (Jacobson organ) is a chemosensory paired tubular organ located on both sides of the nasal septum at its base. It plays an essential role in reproduction process and social behaviors. Objective The current study investigated both anatomical and histological structure of the vomeronasal organ (VNO) in Egyptian native breeds of goats using cross sectional anatomy, histological techniques and computed tomography (CT). Methodology A total of thirty heads obtained from adult and apparently healthy goats of both sexes were collected from Beni-Suef slaughterhouse in Beni-Suef province, Egypt then subjected to anatomical, histological and computed topographical studies. Results Grossly, the VNO appeared as two blind ducts on the either sides of the nasal septum at the floor of nasal cavity extending from the nasal opening of incisive papilla rostrally to the upper 2nd premolar teeth caudally. It connected with mouth by two nasopalatine ducts. The histological examinations revealed two types of lining epithelium; non sensory type lining the cranial portion and the lateral wall of the middle portion of the vomeronasal duct (VND), whereas an olfactory type was the lining epithelium of the medial wall of the middle and the whole caudal portions. The lamina propria submucosa exhibited vascular loose connective tissues, serous glands, nerve bundles and encapsulated by hyaline cartilage. Conclusion The obtaining olfactory epithelium in VNO may indicate an essential role of this organ in sexual relationships and sociosexual behaviors through perception of pheromones.

      PubDate: 2017-03-27T14:57:24Z
      DOI: 10.1016/j.bjbas.2017.03.003
       
  • Supplementary studies of Pleurogenoides medians (Digenea:
           Lecithodendriidae) infecting the Marsh frog Rana Ridibunda (Amphibia:
           Ranidae) in Egypt

    • Authors: Rewaida Abdel-Gaber; Sherein Maher; Reem Kamel; Nashwa El Deeb
      Abstract: Publication date: Available online 9 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Rewaida Abdel-Gaber, Sherein Maher, Reem Kamel, Nashwa El Deeb
      Pleurogenoides medians, a digenean lecithodendriid trematode, parasitize numerous aquatic vertebrate species including frogs, freshwater fish, urodeles and anurans. In the present study, a total of 190 out of 300 (63.33%) marsh frogs Rana Ridibunda were found to be infected with this digenean parasite. The highest percentage of infection was recorded in winter reaching 93.33%, and the lowest value was recorded to be 6.66% during summer. Prevalence and intensity of infection were positively correlated with the host size. Host sex showed no effect in this respect. Morphological studies based on light and scanning electron microscopy revealed that the adult worms characterized by small body size measured 1.980-2.430 (2.205±0.1) mm long and 0.870-1.20 (9.87±0.01) mm wide with spines of similar size distributed all over the body surface; oral sucker is sub-terminal and measured 0.180-0.230 (0.203±0.01) mm long and 0.120-0.180 (0.150±0.01) mm wide; ventral sucker is smaller than the oral sucker, post-ovarian located at 1/3 level from the anterior end and measured 0.080-0.102 (0.090±0.001) mm long and 0.100-0140 (0.120±0.001) mm wide; two symmetrical testes were located near the cecal termination on both sides of the ventral sucker, measured 0.153-0.193 (0.176±0.01) mm long and 0.160-0.192 (0.175±0.01) mm wide; pre-acetabular ovary was present and measured 0.130-0.150 (0.140±0.01) mm long and 0.100-0.130 (0.120±0.01) mm wide; vitellaria are extra-caecal and extended from the level of the pharynx to a level slightly beyond the ovary. By comparing the recovered parasite with different species of the same genus from different hosts having different localities, it was found that the present species morphometrically more or less different from the comparable species and the only similar species was P. medians described previously from the common toad Bufo bufo by having all similar characteristic features. In addition, the present study was considered as the first report for the occurrence of this lecithodendriid species infecting the marsh frog in Egypt.

      PubDate: 2017-03-15T14:48:32Z
      DOI: 10.1016/j.bjbas.2017.03.001
       
  • Cypermethrin-induced histopathological, ultrastructural and biochemical
           changes in liver of albino rats: The protective role of Propolis and
           Curcumin

    • Authors: Manal Abdul-Hamid; Nadia Moustafa; Abd El Mawgoud Abd Alla Asran; Lila Mowafy
      Abstract: Publication date: Available online 8 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Manal Abdul-Hamid, Nadia Moustafa, Abd El Mawgoud Abd Alla Asran, Lila Mowafy
      Cypermethrin (CYP), an insecticide belongs to a synthetic pyrethroid, is used for agriculture and household applications. The present study aimed to examine the toxic effects of CYP on rat liver and to clarify the hepatoprotective effects of propolis (PRO) and curcumin (CUR) against CYP. This study was assessed in male albino rats, each weighting (120-150 g). The rats were equally divided into six groups as follow; the 1st control group, 2nd PRO group (100 mg/kg/day) and 3rd CUR group (100 mg/kg/day). While 4th, 5th and 6th groups were orally treated with CYP (30 mg/kg/day), CYP plus PRO and CYP plus CUR, respectively for 28 days. The present study revealed that CYP-induced significant increase in hepatic markers enzymes (ALT, AST and ALP) and elevation in MDA concomitant with significant decrease of SOD and GPx levels. Histological and histochemical results revealed extensive vacuolar degeneration of hepatocytes, fatty change, blood vessel congestion and fibrosis in the liver of CYP- treated group and depletion of glycogen, protein and DNA. Moreover, ultrastructural observations showed vacuolation, damage of mitochondria and nuclear changes. On the other hand, treatment with PRO and CUR led to an obvious improvement of the injured liver tissues and ameliorating the damaging effects of CYP. In conclusion, PRO is markedly effective than CUR in protecting rats against CYP-induced histopathological, ultrastructural and biochemical changes. This protection may be due to its antioxidant properties and scavenging abilities against active free radicals.

      PubDate: 2017-03-15T14:48:32Z
      DOI: 10.1016/j.bjbas.2017.03.002
       
  • Reproductive responses of primiparous and multiparous Holstein cows
           submitted to presynch-ovsynch protocol

    • Authors: R.L. Abdel Aziz; A. Abdel-Wahab
      Abstract: Publication date: Available online 2 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): R.L. Abdel Aziz, A. Abdel-Wahab
      The specific objective of this study was to determine the reproductive responses of primiparous (n=446) and multiparous (n=726) Holstein cows submitted to 12-day presynch-ovsynch protocol under the Egyptian circumstances. Distribution of inter-estrus intervals (IEI) and conception rate to first insemination (FICR) was compared between primiparous and multiparous cows. Furthermore, Seasonal variations of heat detection rate (HDR), conception rate (CR) and pregnancy rate (PR) were investigated. Short IEI tended to be higher in multiparous cows (23.8 vs 20.44%, P=0.09) compared to primiparous cows. In addition, the incidence of prolonged IEI was decreased from 21.53% in multiparous cows to 16.77% in primiparous cows. On contrary, normal length IEI was 62.78% in primiparous cows, higher than that observed in multiparous cows (54.67%). Moreover, primiparous cows inseminated earlier postpartum (<50 days) achieved higher FICR (31.79%) than multiparous cows (24.46%). Controversially, a tendency toward higher FICR was observed for multiparous cows inseminated after 70 days postpartum (31.89% vs. 23.17%, respectively; P=0.15). No clear variations in HDR were observed among different seasons, whereas greater CR and PR (P<0.05) were achieved by cows inseminated during Winter (35.37 and 24.90) and Spring (36.36 and 24.68), compared to those inseminated during Summer (10 and 6.6) and Autumn (21.59 and 15.63). Conceivably, our results demonstrate that primiparous Holstein cows responded better than multiparous cows to the 12-day presynch-ovsynch protocol as evidenced by higher incidence of normal length IEI, lower incidence of short and prolonged IEI and higher FICR. Furthermore, Summer season had significant negative and delayed effects on fertility of Holstein cows submitted to the 12-day Presynch-ovsynch protocol.

      PubDate: 2017-03-07T14:42:59Z
      DOI: 10.1016/j.bjbas.2017.02.005
       
  • Parameter identification for nonlinear damping coefficient from
           large-amplitude ship roll motion using wavelets

    • Authors: D. Sathyaseelan; G. Hariharan; K. Kannan
      Abstract: Publication date: Available online 27 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): D. Sathyaseelan, G. Hariharan, K. Kannan
      In this paper, we have introduced an efficient Legendre wavelet spectral method (LWSM) to ship roll motion model for investigating the nonlinear damping coefficients. The accuracy of the proposed method is assessed by rolling with an initial amplitude using nonlinear type of equations. To the best of our knowledge until now there is no rigorous wavelet solution has been reported for the above model. Convergence analysis of the proposed method is discussed. The operational matrix of derivative is utilized to convert a ship roll motion equation into a set of algebraic equations. Accurate coefficients can be easily obtained for large rolling angles up to the amplitude at the maximum value of the restoring moment using wavelets. Some numerical examples are given to show the validity and applicability of the proposed wavelet method. Moreover the use of Legendre wavelets is found to be simple,flexible, accurate, efficient and small computation cost.

      PubDate: 2017-03-01T14:39:16Z
      DOI: 10.1016/j.bjbas.2017.02.003
       
  • Meta-analysis of Staphylococcal Diarrhea in Some Developing African
           Countries

    • Authors: George P. Einstein; Orien L. Tulp; Temitope C. Oyesile; Olayide F. Obidi
      Abstract: Publication date: Available online 22 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): George P. Einstein, Orien L. Tulp, Temitope C. Oyesile, Olayide F. Obidi
      Staphylococcal diarrhea is a common gastro-intestinal illness caused by poor water supply and unhygienic food preparation. Although, about 70% of diarrheal cases per year have been attributed to the consumption of contaminated foods, in Africa, few studies have reported the incidence of Staphylococcus-related diarrhea and the implicated virulence factors. We investigated the implications of common factors such as age of children, age of mothers, maternal level of education, gender of children, overall bacteria isolated, sanitary condition status and feeding type of mothers on the burden of staphylococcal diarrhea. A literature search was performed using Pubmed, Googlescholar, American society for microbiology (ASM) journals and other sources. The quality of studies was assessed. Adjusted odds ratios with 95% confidence intervals (CI) for the occurrence of staphylococcus aureus amongst other causes were extracted. For each study, a multivariate logistic regression analysis of the adjusted odds ratio was performed to identify the risk factors on the burden of staphylococcal diarrhea. Six case-control studies were included in the meta–analysis. Quality of individual studies rages from 0.57–0.84 (median, 0.69). Meta-analysis gave pooled odds ratios 3.27 (95% CI; 2.88–4.17). The results identified inadequate sanitary conditions and type of feeding as major risk factors.

      PubDate: 2017-03-01T14:39:16Z
      DOI: 10.1016/j.bjbas.2017.02.004
       
  • Flow Improvement at Pump Intake by the Use of Baffle Posts

    • Authors: Mohamed Mohamed Abdellatif Mohamed
      Abstract: Publication date: Available online 16 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed Mohamed Abdellatif Mohamed
      Poor design of intake structures surrounding the hydraulic pump causes undesirable flow problems. These flow problems are in the form of severe vortices, and/or uneven flow distribution at pump intake. There are several methods in the literature to suppress such vortices but such methods might have an adverse impact on the operation and maintenance of the intake structure. In this paper, a new approach was investigated to reduce the vortex activity without any adverse impacts on the operation process. This approach depends on installing baffle posts on the top of the upstream side and the offshore long side of the sedimentation basin of the intake structure. An existing physical model of undistorted scale 1:38 was utilized to reduce the vortex activity using baffle posts. The model shows that baffle posts are effective in eliminating the vortex activity and hence improving the approach flow at the intake structure.

      PubDate: 2017-02-22T02:34:21Z
      DOI: 10.1016/j.bjbas.2017.02.002
       
  • Underutilized Luffa cylindrica sponge: A local bio-adsorbent for the
           removal of Pb (II) pollutant from water system

    • Authors: Adewale Adewuyi; Fabiano Vargas Pereira
      Abstract: Publication date: Available online 16 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Adewale Adewuyi, Fabiano Vargas Pereira
      Biosorption of Pb2+ ions from aqueous solution onto Luffa cylindrica sponge as adsorbent (LCSA) was investigated in batch adsorption system. LCSA was characterized by X-ray Diffraction analysis technique (XRD), Scanning Electron Microscopy (SEM) coupled with energy dispersive spectroscopy (EDS), Fourier Transform Infrared spectrometer (FTIR), particle size dispersion, zeta potential, thermogravimetric analysis (TGA), and Brunauer-Emmett-Teller (BET) surface area analyzer. The sorption of Pb2+ ions by LCSA was subjected to equilibrium, thermodynamics and kinetic studies and was carried out by considering the effects of pH, initial metal ions concentration, contact time and temperature. BET surface area of LCSA was 6.00 m2/g with mean distribution size of 0.02 micron while the zeta potential was found to increase as the value of pH increased from 4-14. The findings revealed the maximum equilibrium adsorption capacity to be 75.853 mg/g. The process is chemisorptive and controlled by intra-particle diffusion. The values of thermodynamic parameters such as ΔGo, ΔHo and ΔSo showed a stable adsorbent-adsorbate (LCSA-Pb) configuration which is exothermic. The adsorption capacity of LCSA compared better than some natural bio-sorbent found in literature.

      PubDate: 2017-02-22T02:34:21Z
      DOI: 10.1016/j.bjbas.2017.02.001
       
  • Staphylococcal Bacteraemia among Human Immunodeficiency Virus Positive
           Patients at a Screening Center in Lagos, Nigeria

    • Authors: Solayide A. Adesida; Olusegun A. Abioye; Babajide S. Bamiro; Kehinde O. Amisu; Sikiru O. Badaru; Akitoye O. Coker
      Abstract: Publication date: Available online 3 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Solayide A. Adesida, Olusegun A. Abioye, Babajide S Bamiro, Kehinde O Amisu, Sikiru O Badaru, Akitoye O Coker
      Bacteraemia due to Staphylococcus aureus in Human immunodeficiency virus (HIV) - positive patients is associated with increased mortality rate. The present study aimed at determining the species distribution and occurrence of staphylococcal bacteremia in HIV – positive patients in Lagos, Nigeria. Staphylococcal blood stream infection in febrile HIV patients was investigated by culture technique. The antibiotic resistance pattern was investigated using the disk diffusion and methicillin resistance was confirmed by the salt agar methods. The genetic relatedness of S. aureus was determined using Pulsed Field Gel Electrophoresis (PFGE). Eighty-six patients comprising 47 (55%) female and 39 (45%) male, median aged 34 years took part in the study. Staphylococci were identified in 16 (18.6%) patients; 13 (15.1%) and 3 (3.5%) with single and dual Staphylococcus species respectively. The isolates consisted of S. aureus (7 patients), followed by S. haemolyticus (4 patients). Of the thirteen (13) antibiotics tested, isolates were resistant to ampicillin (AMP; 89.5%), tetracycline (TET; 68.4%), cloxacillin (CXC; 89.5%), oxacillin (OXA; 68.4%); chloramphenicol (CHL; 57.9%) and trimethoprim-sulphamethoxazole (SXT; 63.1%). The overall percentage of all the isolates resistant to gentamicin, erythromycin and amoxicillin-clavulanic acid was less than 50%. The isolates were ciprofloxacin and vancomycin susceptible. None of the isolates was positive for methicillin resistance except strain of S. haemolyticus. A significant genetic diversity was observed among S. aureus isolates with a predominant pulsotype A. The two isolates with pulsotype A also had identical resistotype (AMP, ERY, TET, CXC, SXT). Other PFGE patterns were represented by single isolates except pulsotype C which had a subtype. In these patients, the most frequent Staphylococcus species isolated was S. aureus and the results revealed that clonal dissemination of a virulent pulsotype of S. aureus among this population is plausible and should be a cause for concern.

      PubDate: 2017-02-09T02:25:16Z
      DOI: 10.1016/j.bjbas.2016.08.006
       
  • Efficacy and Toxicity of Once Versus Twice Daily Regimens of Amikacin in
           Febrile Neutropenic Pediatric Cancer Patients

    • Authors: Reda Abd-Elfattah; Alaa M.A. Elhdad; Ahmed Khames; Mohmed E.A. Abdelrahim; Samia A. Shouman
      Abstract: Publication date: Available online 1 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Reda Abd-Elfattah, Alaa M.A. Elhdad, Ahmed Khames, Mohmed E.A. Abdelrahim, Samia A. Shouman
      Purpose To compare the pharmacokinetic profile, clinical efficacy and toxicity of once-daily dosing of amikacin compared to twice-daily dosing among pediatric cancer patients with fever and neutropenia. Methods 134 Pediatric patients with hematological malignancies were randomly assigned to receive 15 mg/kg/day amikacin intravenously, either once or twice-daily dosing. For pharmacokinetics, two blood samples were obtained from each patient, the first sample was taken after 1hr from the beginning of infusion and the second sample was taken after 3hr from the first sample. Treatment success was considered when the patient improved without a change in the assigned antibiotic regimen or mortality from infection. Nephrotoxicity was assessed by following the increase in serum creatinine level. Results Pharmacokinetic data revealed superiority in once-daily dosing where Maximum concentration Cmax, Area under the concentration time curve in 24hr AUC24 and Elimination half-life t1/2 were a significantly higher while Minimum concentration Cmin, elimination rate constant Ke and clearance CL were significantly lower in once-daily dosing compared to the twice-daily dosing. Clinical response achieved in 76.8% in once-daily group compared to 69.2% in twice-daily group. Nephrotoxicity was recorded in two patients in once-daily group and six patients in the twice-daily group. After stratifying our patients according to age, a significant increase was observed in the volume of distribution V and CL in pediatrics with age ⩽five compared to >five years. Cmax and AUC24 were significantly lower in the age group of ⩽five years. Conclusions Clinical efficacy and nephrotoxicity were slightly improved in once-daily dosing compared to twice-daily dosing.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.006
       
  • Schistosomiasis haematobium prevalence among haematuric patients:
           parasitological and immuno-assay

    • Authors: Marwa A. Ghieth; Amr M. Lotfy
      Abstract: Publication date: Available online 1 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Marwa A. Ghieth, Amr M. Lotfy
      Schistosoma haematobium infection is a clinically important water born parasitic disease. This study was conducted to detect the prevalence of schistosomiasis haematobium among haematuric patients by microscopy and immunoassay. About 474 symptomized patients with urological manifestations and attending Beni-Suef University Hospital, Egypt were subjected to microhaematuria detection using dipstick reagent strip. Positive patients for microhaematuria were subjected to parasitological and immunological assay to detect S. haematobium eggs and antibodies. Haematuria prevalence was 17.7% (n=84). Egg of S. haematobium wasn’t detected by microscopic examination of urine sediment of all haematuric patients, immunological prevalence of Schistosoma antibodies was 46.4% (n=39). On comparing seropositive and seronegative patients for schistosomiasis antibodies none of the sociodemographic or clinical data were statistically significant. It was concluded that, negative microscopy for schistosomiasis doesn’t exclude infection. Combination of both clinical and epidemiological data in addition to sensitive diagnostic tools is essential for schistosomiasis. There is a critical need to develop more sensitive method to detect true prevalence of schistosomiasis.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.007
       
  • A new fuzzy regression model based on interval-valued fuzzy neural network
           and its applications to management

    • Authors: Somaye yeylaghi; Mahmood Otadi; Niloofar Imankhan
      Abstract: Publication date: Available online 28 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Somaye yeylaghi, Mahmood Otadi, Niloofar Imankhan
      In this paper, a novel hybrid method based on interval-valued fuzzy neural network for approximate of interval-valued fuzzy regression models, is presented. The work of this paper is an expansion of the research of real fuzzy regression models. In this paper interval-valued fuzzy neural network (IVFNN) can be trained with crisp and interval-valued fuzzy data. Here a neural network is considered as a part of a large field called neural computing or soft computing. Moreover, in order to find the approximate parameters, a simple algorithm from the cost function of the fuzzy neural network is proposed. Finally, we illustrate our approach by some numerical examples and compare this method with existing methods.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.004
       
  • Oxidative stress biomarkers in Clarias gariepinus (Burchel, 1822) exposed
           to Microcystin-LR

    • Authors: Isibor Patrick Omoregie
      Abstract: Publication date: Available online 20 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Isibor Patrick Omoregie
      Stress levels inflicted by microcystin-LR extracted from microcystis aeruginosa were assessed by estimating the effects on the oxidative stress biomarkers in the liver, muscle and gill tissues of Clarias garriepinus. Microcystin-LR was administered to the fish by injection into their intra-peritoneal cavity. Microcystin-LR induced the activities of mainly Glutathion-S-Transferase, Catalase and Superoxide dismutase in the liver on dose and temporal basis, while it inhibited the activities of Cytochrome P450 on temporal basis in the liver and gill. Results show that MC-LR significantly induced oxidative stress in the C. gariepinus. Findings show that 400 μg MC-LR/kg b.w. disrupted the antioxidant status of the fish without any external physical manifestation on the body. Microcystin-LR induced the activities of mainly GST, CAT and SOD in the liver on dose and temporal basis while it inhibited the activities of CYP450 on temporal basis in the liver and gill. The adopted MC-LR doses; particularly 400 μgMC-LR/kg b.w. inflicted stress on the fish without any external/ physical manifestation. MC-LR impacted on the antioxidant enzymes in the fish; in the order of liver > gill > muscle. This research has provided empirical evidences that 400 μg MC-LR/kg b.w induced oxidative stress in C. gariepinus in less than a month of exposure. This adopted level of MC-LR can be used as a warning signal in natural water bodies and commercial C. gariepinus ponds.

      PubDate: 2017-01-27T02:17:02Z
      DOI: 10.1016/j.bjbas.2017.01.005
       
  • Kinetics of inhibition of carbohydrate-metabolizing enzymes and mitigation
           of oxidative stress by Eucomis humilis Baker bulb

    • Authors: Mutiu Idowu Kazeem; Anofi Omotayo Tom Ashafa
      Abstract: Publication date: Available online 16 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mutiu Idowu Kazeem, Anofi Omotayo Tom Ashafa
      This study sought to evaluate the in-vitro inhibitory effect of E. humilis bulb extracts on diabetes related enzymes and oxidative stress. Aqueous, ethanol and hydro-ethanol extracts of E. humilis bulb were tested for their inhibitory effects on diabetes-linked enzymes (α-amylase, α-glucosidase, maltase and sucrase). This was followed by evaluation of the ability of these extracts to scavenge 1,1-diphenyl-2-picrylhydrazyl (DPPH), hydroxyl as well as superoxide radical, and iron chelation activity. Ethanol extract of E. humilis exhibited the most potent inhibitory effect on α-amylase (IC50: 79.12 μg/mL), α-glucosidase (IC50: 3.51 μg/mL), maltase (IC50: 37.69 μg/mL) and sucrase (IC50: 30.09 μg/mL). Ethanol extract of E. humilis also inhibited both α-amylase and sucrase non-competitively while α-glucosidase and maltase were both inhibited in a competitive manner. Ethanol extract also displayed most potent hydroxyl (EC50: 66.46 μg/mL) and superoxide (EC50: 22.30 μg/mL) radical scavenging abilities, while aqueous extract scavenges DPPH radical (EC50: 17.12 μg/mL) and chelate iron (EC50: 43.13 μg/mL) most. It can be concluded that ethanol extract of E. humilis displayed the most potent antidiabetic and antioxidant activities, and one of its mechanism of antidiabetic action is through the inhibition of carbohydrate-metabolizing enzymes.

      PubDate: 2017-01-20T02:11:43Z
      DOI: 10.1016/j.bjbas.2017.01.002
       
  • Seasonal fluctuation of trypanosomiasis in camels in North-West Egypt and
           effect of age, sex, location, health status and vector abundance on the
           prevalence

    • Authors: Hassan M. Sobhy; Safaa M. Barghash; Tahani S. Behour; Esam A. Razin
      Abstract: Publication date: Available online 9 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Hassan M. Sobhy, Safaa M. Barghash, Tahani S. Behour, Esam A. Razin
      Follow-up surveys of the blood parasites of the livestock and their possible vectors are recommended to assess their distribution and infection rates in different areas in Egypt and to plan control measures against their vectors. By this study, the authors have completed a comprehensive survey of the extent of Trypanosoma evansi infection in North-West Egypt from November 2014 to October 2015, using blood film examination and RoTat1.2 PCR-based assay. The present study was carried out in the frame of PROCAMED project, supported by the European Union (ENPI-Joint operational Programme of the Mediterranean Basin-IEVP-CT). Historical data of our previous and the present survey have shown that trypanosomiasis in this particular area is constant and not subject to change over time. In addition, the present study has clarified that T. evansi is endemic in this area due to the interaction of a wide range of factors and features of the host which determine patterns of trypanosomiasis, and its distribution coincides with the distribution ofvectors.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2017.01.003
       
  • Synthesis, physicochemical studies and biological evaluation of
           unimetallic and heterobimetallic complexes of hexadentate dihydrazone
           ligands

    • Authors: Fathy A. El Saied; Mokhles M. Abd-Elzaher; Abdou S. El Tabl; Mohamad M.E. Shakdofa; Anas J. Rasras
      Abstract: Publication date: Available online 7 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Fathy A. El Saied, Mokhles M. Abd-Elzaher, Abdou S. El Tabl, Mohamad M.E. Shakdofa, Anas J. Rasras
      A new coordination unimetallic and heterobimetallic complexes of hexadentate N2O4 donor dihydrazone ligands were prepared by the condensation of 4-formyl antipyrine with adipic dihydrazide and succinic dihydrazide. The ligands (1) and (11) and their complexes thoroughly characterized using various analytical, physical and spectroscopic techniques, which indicate a distorted octahedral geometry around the metal ions. The ESR spectra of solid copper(II) complexes (2–4) and (12–14) showed axial symmetry with g >g⊥>ge, indicating distorted octahedral structure and the presence of the unpaired electron in a d (x2−y2) orbital with significant covalent bond character. The antimicrobial activity results of the metal compounds (2–5), (7), (10), (12–15) and (17) show that, all these complexes exhibit inhibitory moderate to mild effects towards Bacillus subtilis, Escherichia coli and Aspergillus niger.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.005
       
  • Behavioral and neurochemical evaluation of ethanol on olanzapine treated
           methylphenidate induced manic like behaviors in swiss albino mice

    • Authors: Thangavel Tamilselvan; Saiful Alom Siddique; Manikannan Vishnupriya; Ganapathy Sindhu; Elumalai Balamurugan
      Abstract: Publication date: Available online 6 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Thangavel Tamilselvan, Saiful Alom Siddique, Manikannan Vishnupriya, Ganapathy Sindhu, Elumalai Balamurugan
      The present study was aimed to evaluate the effect of olanzapine (OLZ) with ethanol (EtOH) on methylphenidate (MPD) induced mania in Swiss albino mice. The effect of EtOH on OLZ treated MPD induced mice by analysing the behavioral activities in Open field test (OFT), forced swimming test (FST) and the neurotransmitter levels for Dopamine (DA), Norepinephrine (NE), serotonin (5-HT) and γ-Aminobutyric acid (GABA). We assayed by considerably found that repeated administration of MPD (2 mg/kg b.w) produced hyperactivity. MPD induced manic like behavioral was manifested by the increased locomotor activities in open field test (central, peripheral and rearing in 5 min). In forced swim test (FST) increased swimming and decreased immobility time (5 min) in MPD treated mice. In fluorimetric micromethod, MPD administrated mice increased DA, NE, 5-HT levels and decreased the GABA levels in the PFC on 21 days. The results of the present study reported that the OLZ treated mice controlled the mania like behavioral activities and neurotransmitter levels in MPD subjected mice. EtOH enhanced the locomotor activities, immobility time, DA, NE and GABA levels. In addition, EtOH reduced swimming and 5-HT level of the brain. From this result EtOH impairs the OLZ treatment and enhanced the locomotor activity and did not prevent neurotransmitter levels in brain tissue. Further studies will be needed to discover the mechanisms responsible for these findings.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2017.01.001
       
  • In vitro antioxidant activity, total phenolic and flavonoid contents of
           ethanol extract of stem and leaf of Grewia carpinifolia

    • Authors: Olamide E. Adebiyi; Funsho O. Olayemi; Tan Ning-Hua; Zeng Guang-Zhi
      Abstract: Publication date: Available online 4 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Olamide E. Adebiyi, Funsho O. Olayemi, Tan Ning-Hua, Zeng Guang-Zhi
      Free radicals are reactive molecules involved in many physiological processes and have been associated with many diseases, such as cancer, arthritis and liver injury. As a result, there is need to explore substances with free radical scavenging and or antioxidant activity. The present study was designed to evaluate the free radical scavenging activity of ethanol extract of leaf and stem of Grewia carpinifolia using various in vitro models. Ascorbic acid was used as the reference in the study. 1,1-Diphenyl-2-picryl hydroxyl (DPPH) quenching assay, 2,2′-azinobis-3-ethylbenzothiozoline-6-sulfonic acid (ABTS) cation decolorization test, ferric reducing antioxidant power (FRAP) Assay systems were selected for the present experiment. The ability of the extracts to inhibit lipid oxidation was measured using Thiobarbituric Acid Reactive Substances (TBARS) assay. The extracts were used at 0.2, 0.4, 0.6, 0.8 and 1mg/ml concentrations and radical scavenging activity was determined in terms of inhibition percentage. The IC50 (concentration required for 50% inhibition) was also calculated for each radical. The study revealed that Grewia carpinifolia has a high radical scavenging activity in the various radical systems. The total phenolic content was 19.08±1.21mg gallic acid equivalent (GAE)/g extract and 14.85±1.09mg GAE/g extract for the leaf and stem respectively while the flavonoid content was 9.00±0.13 and 13.22±1.53mg quercetin/g extract. The antioxidant activity of Grewia carpinifolia extract may be due to the high level of flavonoids and phenols in the plant.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.003
       
  • Microwave-assisted synthesis, structural activity relationship and
           biological activity of some new quinoxaline Schiff base derivatives as
           highly potent spirochete bactericidal agents

    • Authors: Chandravadivelu Gopi; Vedula Girija Sastry; Magharla Dasaratha Dhanaraju
      Abstract: Publication date: Available online 4 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Chandravadivelu Gopi, Vedula Girija Sastry, Magharla Dasaratha Dhanaraju
      The main aim of this work was to synthesise a new (E)-3-(4-or3-Aminophenylimino) quinoxaline-2(3H)-one oxime Schiff base derivatives and evaluate the anti-leptospiral activity against Leptospira icterohaemorrhagiae. The mentioned derivatives were prepared by performing microwave-assisted condensation reactions of (E)-3-(4-or3-Aminophenyl imino)quinoxaline-2(3H)-one and aromatic aldehydes. The structures of these interesting compounds were characterised by FT-IR, 1H NMR and mass spectroscopy. Furthermore, these compounds were screened for spirocidal activity against Leptospira icterohaemorrhagiae by using in vitro and in vivo method. The anti-leptospiral activity result reveals that most of the compounds were exhibiting considerable activity against Leptospira icterohaemorrhagiae. Compound 6c demonstrated remarkable activity at low concentration against the Leptospira icterohaemorrhagiae as compared to the standard drugs.

      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.007
       
  • Microwave assisted, solvent-free synthesis and in-vitro antimicrobial
           screening of some novel pyrazolo[3,4-d]pyrimidin-4(5H)-one derivatives

    • Authors: Dipen K. Sureja; Kantilal R. Vadalia
      Abstract: Publication date: Available online 31 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Dipen K. Sureja, Kantilal R. Vadalia


      PubDate: 2017-01-12T02:06:49Z
      DOI: 10.1016/j.bjbas.2016.12.006
       
  • Isolation of chemical constituents fromNonomuraea species: Invitroandin
           silicoevaluation of its antibacterial properties

    • Authors: P. Saravana Kumar; A. Stalin; R. Lakshmisundaram; V. Duraipandiyan; Naif Abdullah Al-Dhabi; P. Yuvaraj; K. Balakrishnan; S. Ignacimuthu
      Abstract: Publication date: Available online 28 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): P. Saravana Kumar, A. Stalin, R. Lakshmisundaram, V. Duraipandiyan, Naif Abdullah Al-Dhabi, P. Yuvaraj, K. Balakrishnan, S. Ignacimuthu
      An actinomycetes strain VAS16 was isolated from the soil collected from the agricultural field of Vengodu. The strain was identified as Nonomuraea species based on morphological, physiological and biochemical characteristics along with 16S rRNA gene sequence analysis. The active extract was purified over silica gel column chromatography. The structure of the active compound was elucidated using FT-IR, EI-MS, 1H NMR and 13C NMR spectra; it was identified as phthalic acid. Phthalic acid obtained from the strain Nonomuraea sp. VAS16 showed significant antibacterial activity against Yersinia enterocolitica and Vibrio parahaemolyticus, with a MIC value of 31.25μg/mL. In silico docking analysis was carried out using GlcN-6-P synthesis as a target. It showed that the compound had minimum binding energy of -6.55KJ/mol and had good affinity. This compound could be probed further for its usefulness as a drug molecule.

      PubDate: 2017-01-01T05:59:30Z
      DOI: 10.1016/j.bjbas.2016.12.004
       
  • Hypoglycemic and hypolipidemic effects of ethanolic and aqueous extracts
           from Ziziphus oenoplia (L) Mill on alloxan-induced diabetic rats

    • Authors: Pramod Mourya; Ajay Shukla; Gopal Rai; Santram Lodhi
      Abstract: Publication date: Available online 21 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Pramod Mourya, Ajay Shukla, Gopal Rai, Santram Lodhi
      The objective of present study was to investigate hypoglycemic and hypolipidemic effect of ethanolic and aqueous extracts of Ziziphus oenoplia (L) stem bark against Alloxan induce hyperglycemia in rats. Hyperglycemia was induced by an injection of alloxan monohydrate 150 mg/kg (i.p.). After 72 hr, the rats having Blood Glucose Level (BGL) above 150 mg/dL were selected for the investigation. At two different doses (200 mg/kg and 400 mg/kg b.w.) of aqueous and ethanolic extracts were observed antidiabetic effect for 12 consecutive days. BGL was monitored after 1, 3, 6 and 12 days and compared with Metformin (250 mg/kg). Alpha amylase and alpha glucosidase activity of both extracts were also determined. Phytochemical study revealed the presence of glycosides, flavonoids, alkaloids and terpenoids in ethanol extract and flavonoids, carbohydrates and proteins found in aqueous extract of Z. oenoplia bark. Oral administration of both extracts showed significant (P < 0.05) antihyperglycemic activity in dose dependent manner in alloxan induced diabetic rats. The diabetic rats had significant (P < 0.01) reduction in blood glucose; serum liver enzyme level (AST, ALT, and ALP) and lipid profile were compared with normal rats. Significant effects of aqueous and alcoholic extract in alpha amylase and alpha glucosidase activity were observed in rats. The ethanolic and aqueous extract reveals the reduction in the blood glucose level, inhibition of alpha amylase and alpha glucosidase enzymes which support antidiabetic effect (reduce postprandial glucose levels) of Z. oenoplia and this may be due to presence of flavonoids constituents.

      PubDate: 2016-12-25T05:55:17Z
      DOI: 10.1016/j.bjbas.2016.12.002
       
  • Numerical solution of nonlinear sine–Gordon equation by using the
           modified cubic B-spline differential quadrature method

    • Authors: H.S. Shukla; Mohammad Tamsir
      Abstract: Publication date: Available online 13 December 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): H.S. Shukla, Mohammad Tamsir
      This paper deals with numerical solution of one dimensional nonlinear sine–Gordon. “Modified cubic B-spline differential quadrature method” is used to solve one dimensional nonlinear sine–Gordon. The method reduces the problem to a system of first order ordinary differential equations (ODEs). The resulting system of ODEs is solved by “an optimal five stage and fourth-order strong stability preserving Runge–Kutta (SSP-RK54) method”. Finally, the method is illustrated and compared with existing methods via numerical examples. It is found that the method not only is quite easy to implement, but also gives better results than the ones already existing in the literature.

      PubDate: 2016-12-17T05:49:22Z
       
  • Culture conditions for the production of thermostable lipase by
           Thermomyces lanuginosus

    • Authors: B. Sreelatha; V. Koteswara Rao; R. Ranjith Kumar; S. Girisham; S.M. Reddy
      Abstract: Publication date: Available online 30 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): B. Sreelatha, V. Koteswara Rao, R. Ranjith Kumar, S. Girisham, S.M. Reddy
      In the present investigation lipase production by three strains of thermophilic Thermomyces lanuginosus (GSLMBKU-10, GSLMBKU-13 and GSLMBKU-14) was carried out in submerged fermentation process. Olive oil and triacetin (0.1%) were added to the basal medium, which stimulated the lipase production. The maximum lipase was produced by GSLMBKU-10 and GSLMBKU-13 in yeast extract starch medium supplemented with triacetin (0.1%). The optimum pH was recorded at 6.0, 6.5 and 7.0 by GSLMBKU-10, GSLMBKU-13 and GSLMBKU-14 respectively. T. lanuginosus GSLMBKU-10 strains failed to produce lipase at pH 8.0. The optimum temperature for lipase production was observed at 45 °C by GSLMBKU-14 and GSLMBKU-10, while that for GSLMBKU-13 was at 50 °C. The marginal temperature ranged from 45 °C to 50 °C for both lipase production and vegetative growth by the three strains of T. lanuginosus under study. In conclusion, the GSLMBKU-13 strain was comparatively superior in the production of lipase than the other two strains under investigation.

      PubDate: 2016-12-03T03:50:56Z
      DOI: 10.1016/j.bjbas.2016.11.010
       
  • Insilco Study on the Toxicity of Anti-Cancer Compounds Tested against
           MOLT-4 And P388 Cell Lines Using GA-MLR Technique

    • Authors: David Ebuka Arthur; Adamu Uzairu; Paul Mamza; Stephen Eyije Abechi; Gideon Shallangwa
      Abstract: Publication date: Available online 17 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): David Ebuka Arthur, Adamu Uzairu, Paul Mamza, Stephen Eyije Abechi, Gideon Shallangwa
      The research entails the development of two models that can be used to predict the toxicity of compounds suspected of having anti-leukemia activity, the two models ones for MOLT-4 and the other for P388 cell lines were developed by carefully selecting 5 descriptors in each case from a pool of 4,900 molecular descriptors using GA-MLR method. The ability of the models to predict chemicals that were not used in the preparation set was evaluated by validating the models internally [Q2 CV MOLT-4=0.644 and Q2 CV (P388) =0.641] and externally [R2 pred (P388) = 0.662 and R2 pred (MOLT-4) =0.679], other criteria such as r2 m, R2 p, k and k' were also determined and were found to support R2 pred results of the models. The effect of every descriptor in the model were dictated by calculating their individual mean effect to (pLC50) the toxicities of the compounds. SpMax7_Bhm (1.697) and RDF145u (-4.300) influenced the models the most, while in MOLT-4 the descriptors with the least effect was n-isopropyl (0.0343) and for P388 is 1.162. the models were further validated by subjecting them to y-randomization which finally confirmed the robustness of the models developed.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.003
       
  • Rhusaucheri boiss an omani herbal medicine: identification and in-vitro
           antioxidant and antibacterial potentials of its leaves extracts

    • Authors: Vandita Singh; Fatima Al-Malki; Mohammad Sadat Ali; Philip Fletcher; Nejib Guizani; Omima Al-Saidi; Rahma Al-Hanaai; Rawan Al-bahri; Safiya Al-Ghdani; Syed Sikander Hasan; Hakikulla Hamidulla Shah
      Abstract: Publication date: Available online 17 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Vandita Singh, Fatima Al-Malki, Mohammad Sadat Ali, Philip Fletcher, Nejib Guizani, Omima Al-Saidi, Rahma Al-Hanaai, Rawan Al-bahri, Safiya Al-Ghdani, Syed Sikander Hasan, Hakikulla Hamidulla Shah
      Rhusaucheri Boiss is a popular Omani herbal medicinal plant used as an antiseptic, astringent and homeostatic. In this study we evaluated, the antioxidant and antibacterial potential of R. Boiss leaves using an in-vitro model. Three green solvents i.e. water ethanol and aqueous glycerol was employed to access the extraction of polyphenols and flavonoids. We found the highest polyphenols and flavonoids extraction for aqueous glycerol extracts The antioxidant capacity was assessed using 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical reducing abilities of the three liquid crude extracts (LCEs) and was recorded to be high in water and aqueous glycerol LCEs (91 & 83.1%) respectively. The screening of antibacterial potential was gauged against gram positive bacterial strains namely Staphylococcus aureus (ATCC® 29213™), Staphylococcus aureus (ATCC® 25923™) and Enterococcus faecalis (ATCC® 29212™) as well as one gram negative strain Escherichia coli. The three LCEs were found to be fairly active against the microbial strains tested. Further, we recorded the scanning electron microscopic (SEM) images of the leaves of R. Boiss leaves to underpin the botanical characters of the leaves so that any future studies of this plant will have sound basis.

      PubDate: 2016-11-19T01:30:31Z
      DOI: 10.1016/j.bjbas.2016.11.002
       
  • Approximation of analytic functions in adaptive environment

    • Authors: Saumya Ranjan Jena; Kumudini Meher; Arjun kumar Paul
      Abstract: Publication date: Available online 2 November 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Saumya Ranjan Jena, Kumudini Meher, Arjun kumar Paul
      In this paper, a mixed quadrature rule of degree of precision seven is formed for analytic functions by taking two constituent rules each of degree of precision five. Here the integral of analytic function is converted to real definite integrals with the help of double transformations. Then the mixed quadrature rule is tested in adaptive environment and it is obviously superior to that of Gauss-Legendre three-point rule.

      PubDate: 2016-11-05T01:19:26Z
      DOI: 10.1016/j.bjbas.2016.10.001
       
  • Morphological study of some taxa of Ranunculaceae Juss in Egypt (anatomy
           and pollen grains)

    • Authors: Mohamed A. Salim; Al-Safa H. Mohamed; Mohamed E. Tantawy
      Abstract: Publication date: Available online 29 October 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed A. Salim, Al-Safa H. Mohamed, Mohamed E. Tantawy
      Ranunculaceae is a large angiospermic family (43 genera and 2346 species). Seven taxa were subjected in the present study representing six genera. Stem anatomy, flower anatomy, lamina epidermal characters as well as the pollen morphology were carried out according to traditional taxonomic methods using LM and SEM. The specific target of the present study is to contribute knowledge to Ranunculaceae from different perspectives. The obtained microcharacters of stem, leaf and flowers are considered diagnostic at the generic and specific levels (e.g., stem outline, types of cortex, internal appearance of stem, leaf types, perianth vascularization and presence of nectary scales). The pollen characters of the studied taxa are considered highly diagnostic at the generic and specific levels especially pollen class (trizonocolpate, pantocolpate and pantoporate) and pollen sculpture (aculeate, verrucate-aculeate, aculeate-faveolate and scabrate-verrucate). The obtained data facilitate the construction of artificial keys to delimitation between the studied taxa.

      PubDate: 2016-11-05T01:19:26Z
      DOI: 10.1016/j.bjbas.2016.10.002
       
  • Effect of hydrothermal curing on hydration characteristics of
           metakaolin–CKD pastes at different temperatures in a closed system

    • Authors: Mohamed R. Shatat; Gomaa A.M. Ali; Gamal A. Gouda
      Abstract: Publication date: Available online 27 October 2016
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed R. Shatat, Gomaa A.M. Ali, Gamal A. Gouda
      Well–sealed stainless steel capsule was used as a hydrothermal system to study the pozzolanic activity and hydration characteristics of metakaolin (MK)–cement kiln dust (CKD) at different temperatures (40, 80, 120 and 150 °C) up to 24 hours hydrothermal curing. The physico-chemical properties of hydrothermally treated MK-CKD pastes were studied by measuring the compressive strength, porosity and bulk density of the hardened pastes as hydraulic properties. The hydration properties of the pastes were studied by measuring free lime and chemically-combined water contents. The phase composition and crystalline structure of the obtained hydrates were studied using X–ray diffraction (XRD) and differential thermal analysis (DTA). The results indicated that, the higher activity is shown at 80 °C especially at the later age of hydrothermal curing. Moreover, the mix containing 75 % MK and 25 % CKD by mass possessed the higher characteristics during the later age of hydrothermal curing and at all curing temperatures.

      PubDate: 2016-10-28T22:53:03Z
      DOI: 10.1016/j.bjbas.2016.09.002
       
 
 
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