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  Subjects -> ENGINEERING (Total: 2277 journals)
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ENGINEERING (1203 journals)                  1 2 3 4 5 6 7 | Last

Showing 1 - 200 of 1205 Journals sorted alphabetically
3 Biotech     Open Access   (Followers: 7)
3D Research     Hybrid Journal   (Followers: 18)
AAPG Bulletin     Hybrid Journal   (Followers: 7)
AASRI Procedia     Open Access   (Followers: 15)
Abstract and Applied Analysis     Open Access   (Followers: 3)
Aceh International Journal of Science and Technology     Open Access   (Followers: 2)
ACS Nano     Full-text available via subscription   (Followers: 244)
Acta Geotechnica     Hybrid Journal   (Followers: 7)
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 5)
Acta Polytechnica : Journal of Advanced Engineering     Open Access   (Followers: 2)
Acta Scientiarum. Technology     Open Access   (Followers: 3)
Acta Universitatis Cibiniensis. Technical Series     Open Access  
Active and Passive Electronic Components     Open Access   (Followers: 7)
Adaptive Behavior     Hybrid Journal   (Followers: 11)
Adıyaman Üniversitesi Mühendislik Bilimleri Dergisi     Open Access  
Adsorption     Hybrid Journal   (Followers: 4)
Advanced Engineering Forum     Full-text available via subscription   (Followers: 6)
Advanced Science     Open Access   (Followers: 5)
Advanced Science Focus     Free   (Followers: 3)
Advanced Science Letters     Full-text available via subscription   (Followers: 9)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 7)
Advanced Synthesis & Catalysis     Hybrid Journal   (Followers: 17)
Advances in Calculus of Variations     Hybrid Journal   (Followers: 2)
Advances in Catalysis     Full-text available via subscription   (Followers: 5)
Advances in Complex Systems     Hybrid Journal   (Followers: 7)
Advances in Engineering Software     Hybrid Journal   (Followers: 26)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 16)
Advances in Fuzzy Systems     Open Access   (Followers: 5)
Advances in Geosciences (ADGEO)     Open Access   (Followers: 10)
Advances in Heat Transfer     Full-text available via subscription   (Followers: 22)
Advances in Human Factors/Ergonomics     Full-text available via subscription   (Followers: 26)
Advances in Magnetic and Optical Resonance     Full-text available via subscription   (Followers: 9)
Advances in Natural Sciences: Nanoscience and Nanotechnology     Open Access   (Followers: 29)
Advances in Operations Research     Open Access   (Followers: 11)
Advances in OptoElectronics     Open Access   (Followers: 5)
Advances in Physics Theories and Applications     Open Access   (Followers: 12)
Advances in Polymer Science     Hybrid Journal   (Followers: 41)
Advances in Porous Media     Full-text available via subscription   (Followers: 4)
Advances in Remote Sensing     Open Access   (Followers: 39)
Advances in Science and Research (ASR)     Open Access   (Followers: 6)
Aerobiologia     Hybrid Journal   (Followers: 2)
African Journal of Science, Technology, Innovation and Development     Hybrid Journal   (Followers: 5)
AIChE Journal     Hybrid Journal   (Followers: 32)
Ain Shams Engineering Journal     Open Access   (Followers: 5)
Akademik Platform Mühendislik ve Fen Bilimleri Dergisi     Open Access  
Alexandria Engineering Journal     Open Access   (Followers: 1)
AMB Express     Open Access   (Followers: 1)
American Journal of Applied Sciences     Open Access   (Followers: 28)
American Journal of Engineering and Applied Sciences     Open Access   (Followers: 11)
American Journal of Engineering Education     Open Access   (Followers: 9)
American Journal of Environmental Engineering     Open Access   (Followers: 17)
American Journal of Industrial and Business Management     Open Access   (Followers: 23)
Analele Universitatii Ovidius Constanta - Seria Chimie     Open Access  
Annals of Combinatorics     Hybrid Journal   (Followers: 3)
Annals of Pure and Applied Logic     Open Access   (Followers: 2)
Annals of Regional Science     Hybrid Journal   (Followers: 8)
Annals of Science     Hybrid Journal   (Followers: 7)
Applicable Algebra in Engineering, Communication and Computing     Hybrid Journal   (Followers: 2)
Applicable Analysis: An International Journal     Hybrid Journal   (Followers: 1)
Applied Catalysis A: General     Hybrid Journal   (Followers: 6)
Applied Catalysis B: Environmental     Hybrid Journal   (Followers: 16)
Applied Clay Science     Hybrid Journal   (Followers: 5)
Applied Computational Intelligence and Soft Computing     Open Access   (Followers: 12)
Applied Magnetic Resonance     Hybrid Journal   (Followers: 4)
Applied Nanoscience     Open Access   (Followers: 8)
Applied Network Science     Open Access   (Followers: 1)
Applied Numerical Mathematics     Hybrid Journal   (Followers: 5)
Applied Physics Research     Open Access   (Followers: 3)
Applied Sciences     Open Access   (Followers: 2)
Applied Spatial Analysis and Policy     Hybrid Journal   (Followers: 4)
Arabian Journal for Science and Engineering     Hybrid Journal   (Followers: 5)
Archives of Computational Methods in Engineering     Hybrid Journal   (Followers: 4)
Archives of Foundry Engineering     Open Access  
Archives of Thermodynamics     Open Access   (Followers: 7)
Arkiv för Matematik     Hybrid Journal   (Followers: 1)
ASEE Prism     Full-text available via subscription   (Followers: 3)
Asia-Pacific Journal of Science and Technology     Open Access  
Asian Engineering Review     Open Access  
Asian Journal of Applied Science and Engineering     Open Access   (Followers: 1)
Asian Journal of Applied Sciences     Open Access   (Followers: 2)
Asian Journal of Biotechnology     Open Access   (Followers: 8)
Asian Journal of Control     Hybrid Journal  
Asian Journal of Current Engineering & Maths     Open Access  
Asian Journal of Technology Innovation     Hybrid Journal   (Followers: 8)
Assembly Automation     Hybrid Journal   (Followers: 2)
at - Automatisierungstechnik     Hybrid Journal   (Followers: 1)
ATZagenda     Hybrid Journal  
ATZextra worldwide     Hybrid Journal  
Australasian Physical & Engineering Sciences in Medicine     Hybrid Journal   (Followers: 1)
Australian Journal of Multi-Disciplinary Engineering     Full-text available via subscription   (Followers: 2)
Autonomous Mental Development, IEEE Transactions on     Hybrid Journal   (Followers: 8)
Avances en Ciencias e Ingeniería     Open Access  
Balkan Region Conference on Engineering and Business Education     Open Access   (Followers: 1)
Bangladesh Journal of Scientific and Industrial Research     Open Access  
Basin Research     Hybrid Journal   (Followers: 5)
Batteries     Open Access   (Followers: 6)
Bautechnik     Hybrid Journal   (Followers: 1)
Bell Labs Technical Journal     Hybrid Journal   (Followers: 23)
Beni-Suef University Journal of Basic and Applied Sciences     Open Access   (Followers: 4)
BER : Manufacturing Survey : Full Survey     Full-text available via subscription   (Followers: 2)
BER : Motor Trade Survey     Full-text available via subscription   (Followers: 1)
BER : Retail Sector Survey     Full-text available via subscription   (Followers: 2)
BER : Retail Survey : Full Survey     Full-text available via subscription   (Followers: 2)
BER : Survey of Business Conditions in Manufacturing : An Executive Summary     Full-text available via subscription   (Followers: 3)
BER : Survey of Business Conditions in Retail : An Executive Summary     Full-text available via subscription   (Followers: 4)
Bharatiya Vaigyanik evam Audyogik Anusandhan Patrika (BVAAP)     Open Access   (Followers: 1)
Biofuels Engineering     Open Access   (Followers: 1)
Biointerphases     Open Access   (Followers: 1)
Biomaterials Science     Full-text available via subscription   (Followers: 10)
Biomedical Engineering     Hybrid Journal   (Followers: 16)
Biomedical Engineering and Computational Biology     Open Access   (Followers: 14)
Biomedical Engineering Letters     Hybrid Journal   (Followers: 5)
Biomedical Engineering, IEEE Reviews in     Full-text available via subscription   (Followers: 17)
Biomedical Engineering, IEEE Transactions on     Hybrid Journal   (Followers: 33)
Biomedical Engineering: Applications, Basis and Communications     Hybrid Journal   (Followers: 5)
Biomedical Microdevices     Hybrid Journal   (Followers: 9)
Biomedical Science and Engineering     Open Access   (Followers: 4)
Biomedizinische Technik - Biomedical Engineering     Hybrid Journal  
Biomicrofluidics     Open Access   (Followers: 4)
BioNanoMaterials     Hybrid Journal   (Followers: 2)
Biotechnology Progress     Hybrid Journal   (Followers: 39)
Boletin Cientifico Tecnico INIMET     Open Access  
Botswana Journal of Technology     Full-text available via subscription   (Followers: 1)
Boundary Value Problems     Open Access   (Followers: 1)
Brazilian Journal of Science and Technology     Open Access   (Followers: 2)
Broadcasting, IEEE Transactions on     Hybrid Journal   (Followers: 10)
Bulletin of Canadian Petroleum Geology     Full-text available via subscription   (Followers: 14)
Bulletin of Engineering Geology and the Environment     Hybrid Journal   (Followers: 13)
Bulletin of the Crimean Astrophysical Observatory     Hybrid Journal  
Cahiers, Droit, Sciences et Technologies     Open Access  
Calphad     Hybrid Journal  
Canadian Geotechnical Journal     Hybrid Journal   (Followers: 27)
Canadian Journal of Remote Sensing     Full-text available via subscription   (Followers: 45)
Case Studies in Engineering Failure Analysis     Open Access   (Followers: 8)
Case Studies in Thermal Engineering     Open Access   (Followers: 4)
Catalysis Communications     Hybrid Journal   (Followers: 6)
Catalysis Letters     Hybrid Journal   (Followers: 2)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 8)
Catalysis Science and Technology     Free   (Followers: 7)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 3)
Catalysis Today     Hybrid Journal   (Followers: 8)
CEAS Space Journal     Hybrid Journal   (Followers: 1)
Cellular and Molecular Neurobiology     Hybrid Journal   (Followers: 3)
Central European Journal of Engineering     Hybrid Journal   (Followers: 1)
CFD Letters     Open Access   (Followers: 6)
Chaos : An Interdisciplinary Journal of Nonlinear Science     Hybrid Journal   (Followers: 2)
Chaos, Solitons & Fractals     Hybrid Journal   (Followers: 3)
Chinese Journal of Catalysis     Full-text available via subscription   (Followers: 2)
Chinese Journal of Engineering     Open Access   (Followers: 2)
Chinese Science Bulletin     Open Access   (Followers: 1)
Ciencia e Ingenieria Neogranadina     Open Access  
Ciencia en su PC     Open Access   (Followers: 1)
Ciencias Holguin     Open Access   (Followers: 1)
CienciaUAT     Open Access  
Cientifica     Open Access  
CIRP Annals - Manufacturing Technology     Full-text available via subscription   (Followers: 11)
CIRP Journal of Manufacturing Science and Technology     Full-text available via subscription   (Followers: 14)
City, Culture and Society     Hybrid Journal   (Followers: 23)
Clay Minerals     Full-text available via subscription   (Followers: 10)
Clean Air Journal     Full-text available via subscription   (Followers: 2)
Coal Science and Technology     Full-text available via subscription   (Followers: 3)
Coastal Engineering     Hybrid Journal   (Followers: 11)
Coastal Engineering Journal     Hybrid Journal   (Followers: 5)
Coatings     Open Access   (Followers: 4)
Cogent Engineering     Open Access   (Followers: 2)
Cognitive Computation     Hybrid Journal   (Followers: 4)
Color Research & Application     Hybrid Journal   (Followers: 1)
COMBINATORICA     Hybrid Journal  
Combustion Theory and Modelling     Hybrid Journal   (Followers: 13)
Combustion, Explosion, and Shock Waves     Hybrid Journal   (Followers: 13)
Communications Engineer     Hybrid Journal   (Followers: 1)
Communications in Numerical Methods in Engineering     Hybrid Journal   (Followers: 2)
Components, Packaging and Manufacturing Technology, IEEE Transactions on     Hybrid Journal   (Followers: 27)
Composite Interfaces     Hybrid Journal   (Followers: 6)
Composite Structures     Hybrid Journal   (Followers: 265)
Composites Part A : Applied Science and Manufacturing     Hybrid Journal   (Followers: 189)
Composites Part B : Engineering     Hybrid Journal   (Followers: 258)
Composites Science and Technology     Hybrid Journal   (Followers: 186)
Comptes Rendus Mécanique     Full-text available via subscription   (Followers: 2)
Computation     Open Access  
Computational Geosciences     Hybrid Journal   (Followers: 15)
Computational Optimization and Applications     Hybrid Journal   (Followers: 7)
Computational Science and Discovery     Full-text available via subscription   (Followers: 2)
Computer Applications in Engineering Education     Hybrid Journal   (Followers: 7)
Computer Science and Engineering     Open Access   (Followers: 17)
Computers & Geosciences     Hybrid Journal   (Followers: 28)
Computers & Mathematics with Applications     Full-text available via subscription   (Followers: 6)
Computers and Electronics in Agriculture     Hybrid Journal   (Followers: 4)
Computers and Geotechnics     Hybrid Journal   (Followers: 10)
Computing and Visualization in Science     Hybrid Journal   (Followers: 5)
Computing in Science & Engineering     Full-text available via subscription   (Followers: 31)
Conciencia Tecnologica     Open Access  
Concurrent Engineering     Hybrid Journal   (Followers: 3)
Continuum Mechanics and Thermodynamics     Hybrid Journal   (Followers: 7)
Control and Dynamic Systems     Full-text available via subscription   (Followers: 9)
Control Engineering Practice     Hybrid Journal   (Followers: 43)
Control Theory and Informatics     Open Access   (Followers: 8)
Corrosion Science     Hybrid Journal   (Followers: 25)
CT&F Ciencia, Tecnologia y Futuro     Open Access   (Followers: 1)
CTheory     Open Access  

        1 2 3 4 5 6 7 | Last

Journal Cover Beni-Suef University Journal of Basic and Applied Sciences
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  This is an Open Access Journal Open Access journal
   ISSN (Print) 2314-8535
   Published by Elsevier Homepage  [3049 journals]
  • Design and combinatorial library generation of 1H 1,4 benzodiazepine 2,5
           diones as photosystem-II inhibitors: A public QSAR approach

    • Authors: Purusottam Banjare; Jagadish Singh; Partha Pratim Roy
      Pages: 219 - 231
      Abstract: Publication date: September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences, Volume 6, Issue 3
      Author(s): Purusottam Banjare, Jagadish Singh, Partha Pratim Roy
      Exponential rise in the population around the word increased the demand of food grains/crops with limited expansion of the agricultural land. To meet the demand, generation of new herbicidal agents is of primary need for the manufacturing firm. In silico tool like QSAR is one of the regularly used in designing newer compounds along with wet experiment. Photosystem-II (PS-II) regarded as one of the major target for the herbicidal agents. With this aim in the present study a series of 1H, 1,4 benzodiazepine 2,5-dione analogues as herbicidal (PS-II inhibitors) agents were subjected to QSAR analysis using 2D PaDEL descriptors (open source). Two different splitting techniques namely, kennard stone based and k-means clustering splitting were used to divide the whole data set and GFA based on MAE criteria was used a statistical method to develop a model to investigate the physicochemical and structural requirement of potential PS-II inhibitors. All the models are statistically robust both internally and externally (Q2: 0.540–0.693, R2 pred: 0.722–0.810). The activity is mostly affected by polarizabilities, electro negativities as well as substituents at the phenyl ring. Based on the results, a library of compounds was generated using SmiLib v2.0 tool (open source) and better predicted inside applicability domain compounds were identified by applying three different applicability domain (AD) approaches. Therefore the developed public QSAR models may be helpful for the scientific community for the further research.

      PubDate: 2017-09-15T14:59:21Z
      DOI: 10.1016/j.bjbas.2017.04.003
       
  • Ultrasound assisted one pot expeditious synthesis of new
           pyrido[2,3-d]pyrimidine analogues using mild and inexpensive
           4-dimethylaminopyridine (DMAP) catalyst

    • Authors: Ajmal R. Bhat; Gowhar A. Naikoo; Israr Ul Hassan; Rajendra S. Dongra; Tabassum Ara
      Pages: 238 - 246
      Abstract: Publication date: September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences, Volume 6, Issue 3
      Author(s): Ajmal R. Bhat, Gowhar A. Naikoo, Israr Ul Hassan, Rajendra S. Dongra, Tabassum Ara
      The one-pot three-component reaction for the synthesis of pyrido[2,3-d]pyrimidine derivatives has been reported via initial Knoevenagel, subsequent addition and final heterocyclization of substituted aromatic aldehydes, cyanoacetamide and 6-aminouracil in N,N-dimethylformamide (DMF) solvent using 4-dimethylaminopyridine (DMAP) as new organocatalyst under ultrasound irradiation. The results showed that a series of aromatic aldehydes were successfully used to prepare the targeted pyrido[2,3-d]pyrimidine derivatives with good to excellent yields (81–93%) and there is no major effect on the yield of product by electron donating/withdrawing substituents. Short reaction time, environment friendly procedure, excellent yields, inexpensive and readily available catalyst are the advantages of this procedure. All synthesized compounds were characterized by IR, 1HNMR, 13CNMR and mass spectral data.

      PubDate: 2017-09-15T14:59:21Z
      DOI: 10.1016/j.bjbas.2017.04.005
       
  • Antioxidant and antibacterial activities of various extracts of Inula
           cuspidata C.B. Clarke stem

    • Authors: Sarvesh Kumar Paliwal; Bhawana Sati; Samriti Faujdar; Swapnil Sharma
      Pages: 97 - 105
      Abstract: Publication date: June 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences, Volume 6, Issue 2
      Author(s): Sarvesh Kumar Paliwal, Bhawana Sati, Samriti Faujdar, Swapnil Sharma
      The objective of the present study includes estimation of total phenolic and total flavonoid contents and evaluation of antioxidant and antibacterial activities of various extracts of Inula cuspidata stem. I. cuspidata belongs to family Compositae; it is an erect shrub, distributed in western Himalaya, usually found growing on steep rocky or precipitous ground. Total phenolic and flavonoid contents were estimated by Folin–Ciocalteu and aluminum chloride method. Antioxidant activity was performed by four methods: DPPH (1,1-diphenyl-2-picryl hydrazyl radical), ferrous chelating activity, reducing power and nitric oxide scavenging activity. These extracts were screened for antibacterial studies using macro-dilution method. Total phenolic and flavonoid contents were found to be highest in methanol extract (69.44 ± 1.12 mg GAE/g, 12.45 ± 0.67 mg QE/g) followed by chloroform (33.53 ± 0.88 mg GAE/g, 1.27 ± 0.51 mg QE/g) and n-hexane (12.25 ± 1.03 mg GAE/g, 0.08 ± 0.43 mg QE/g) extracts. Methanol extract of I. cuspidata exhibited potent antioxidant activity in all the antioxidant assays followed by chloroform and n-hexane extracts. IC50 values of methanol, chloroform and n-hexane extract were found to be 43.35 ± 0.58 µg/mL, 298.08 ± 0.62 µg/mL, 1989.24 ± 0.71 µg/mL for DPPH, 396.63 ± 0.73 µg/mL, 915.29 ± 0.81 µg/mL, 1180.56 ± 0.88 µg/mL for ferrous chelating and 594.68 ± 0.99 µg/mL, 930.55 ± 1.03 µg/mL, 1959.26 ± 1.25 µg/mL for nitric oxide scavenging assays. A strong correlation was found between total phenolic, flavonoid and 1/IC50 values obtained by different antioxidant assays. The correlation coefficient (R) value obtained was more than 0.9 which exhibits a strong correlation. All the extracts showed significant antibacterial activities against Gram positive bacterial strains with minimum inhibitory concentration (MIC) values ranging from 187.5 to 750 µg/mL and moderate to weak inhibition against Gram negative bacteria with MIC values ranging from 750 to 3000 µg/mL. The present study proves the in vitro anti-oxidant and antibacterial activities of different extracts of I. cuspidata stem.

      PubDate: 2017-06-02T19:09:13Z
      DOI: 10.1016/j.bjbas.2016.10.003
       
  • Amelioration of anaphylaxis, mast cell degranulation and bronchospasm by
           Euphorbia hirta L. extracts in experimental animals

    • Authors: Ghanshyam Parmar; Kilambi Pundarikakshudu; R. Balaraman; Girish Sailor
      Abstract: Publication date: Available online 9 November 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Ghanshyam Parmar, Kilambi Pundarikakshudu, R. Balaraman, Girish Sailor
      The current investigation was aimed to assess anti-anaphylactic, mast cell stabilizing and anti-asthmatic activity of methanol and aqueous extract of Euphorbia hirta (Euphorbiaceae) on experimental animals. Anaphylaxis was induced by administration of horse serum and triple antigen vaccine subcutaneously in albino Wistar rats. Extracts of E. hirta (EH) were administered to the rats in dose of 250 and 500 mg/kg b.w. orally for 14 days. At the end of treatment, asthma score was measured and various blood parameters like differential count (DC), total WBC count and IgE were estimated. Interleukin (IL)-4, IL-5 and tumour necrosis factor (TNF)-α were measured by ELISA commercial kit from Broncho alveolar lavage fluid (BALF). Histopathological changes of lungs were observed. Anti-asthmatic activity of extracts of EH was also studied on histamine-induced bronchospasm in guinea pigs. In vitro mast cell stabilizing activity of extracts was evaluated on compound 48/80 challenged rat intestinal mesenteric mast cells. The treatment with extracts of EH produced significant decrease in asthma score and they also brought to normalcy the increased total WBC, DC counts, serum IgE, TNF-α, IL-4 and IL-5 in BALF. The histopathological study further supported the protective effect of EH extracts. The pre-treatment with extracts of EH displayed significant reduction in degranulation of mesenteric mast cell numbers. The treatment with extracts of EH significantly increased in time of pre-convulsive dyspnoea (PCD). Thus, these findings concluded that E. hirta could be effectively used in the treatment of anaphylaxis and asthma.

      PubDate: 2017-11-10T11:39:44Z
      DOI: 10.1016/j.bjbas.2017.11.001
       
  • Coordination versatility of N2O4 polydentate hydrazonic ligand in Zn(II),
           Cu(II), Ni(II), Co(II), Mn(II) and Pd(II) complexes and antimicrobial
           evaluation

    • Authors: Fathy A. El-Saied; Mohamad M.E. Shakdofa; Abdou S. El Tabl; Mokhles M. Abd-Elzaher; Nagy Morsy
      Abstract: Publication date: Available online 6 November 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Fathy A. El-Saied, Mohamad M.E. Shakdofa, Abdou S. El Tabl, Mokhles M. Abd-Elzaher, Nagy Morsy
      New polydentate hydrazone ligand, was synthesized by the condensation of 1,5-dimethyl-3-oxo-2-phenylpyrazole-4-carbaldehyde with adipodihydrazide. The structure of the synthesized ligand, N′1,N′6-bis((1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl) methylene) adipohydrazide was elucidated by various analytical and spectroscopic techniques. The reactions of the ligand with zinc(II), copper(II), nickel(II), cobalt(II), manganese(II) and palladium(II) salts afforded homobinuclear metal complexes. Characterization and structure elucidation of the prepared complexes were achieved using different analytical and spectroscopic techniques. The analyses data indicated that this ligand behaved as N2O4 dibasic hexadentate ligand bonded covalency to the metal ions through the enolic carbonyl oxygen of hydrazide moiety and coordinated via carbonyl oxygen of antipyrine moiety and azomethine nitrogen atoms forming distorted octahedral geometry around the metal ions. The ESR spectra of copper(II) complexes (3) and (4) showed an axial symmetry with g >g⊥>ge, indicating distorted octahedral structure and presence of the unpaired electron in d(x2−y2) orbital. The microbicide studies of the ligand and its metal complexes (2), (3), (4), (5), (8), (11) and (13) showed that, all these complexes exhibit moderate to mild inhibitory effects on B. subtilis, E. coli while complexes (2), (3), (4) and (13) exhibit moderate to mild inhibitory effects on A. niger.

      PubDate: 2017-11-10T11:39:44Z
      DOI: 10.1016/j.bjbas.2017.09.005
       
  • Antimicrobial and cytotoxic comparative study of different extracts of
           Omani and SudaneseGum acacia

    • Authors: Said Musallam Al Alawi; Mohammad Amzad Hossain; Ahmed A. Abusham
      Abstract: Publication date: Available online 23 October 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Said Musallam Al Alawi, Mohammad Amzad Hossain, Ahmed A. Abusham
      Gum acacia, known as Gum Arabic in Oman is widely grown all over the tropical countries including Gulf region. The antimicrobial and cytotoxic activities of different polarity organic extracts of Omani and Sudanese Gum acacia latex has been investigated in this study using maceration method. Both Omani and Sudanese Gum acacia latex samples were used to prepare different fractions using various organic solvents. The antimicrobial activity of different organic extracts was determined through disc diffusion method against clinically isolated bacterial strains. The isolated pathogenic bacterial strain are Gram (+) Staphylococcus aureus (S. aureus, Code no. 659), Gram (-) Escherichia coli (E. coli, Code no. 846), Gram (-) Escherichia coli (E. coli, Code no. 683) and Gram (-) Klebsiella pneumoniae (Code no. 684). The antibiotic levofloxacin and dimethyl sulphoxide (DMSO) were used as positive and negative controls. The cytotoxic activity of the above mentioned organic extracts was determined by brine shrimp lethality method (BSL). Both latex samples of various polarity organic extracts at different concentrations showed antimicrobial activity against the isolated human bacterial strains with an inhibition range of 0-15 mm. However, both latex samples did not reveal a significant cytotoxic activity at any concentration. In conclusion, the organic extracts from both types of Gum acacia (Omani and Sudanese) represent a good source of natural antibiotic for the treatment of various infectious diseases.

      PubDate: 2017-10-26T09:42:46Z
      DOI: 10.1016/j.bjbas.2017.10.007
       
  • Apoptotic efficiency of aqueous extracts of turmeric, garlic and their
           active compounds in combination with Tamoxifen in lung and oral cancers: A
           comparative study.

    • Authors: Satish Kumar Vemuri; Rajkiran Reddy Banala; GPV. Subbaiah; Gurava Reddy AV; T Malarvili
      Abstract: Publication date: Available online 23 October 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Satish Kumar Vemuri, Rajkiran Reddy Banala, GPV. Subbaiah, Gurava Reddy AV, T Malarvili


      PubDate: 2017-10-26T09:42:46Z
      DOI: 10.1016/j.bjbas.2017.10.006
       
  • Effect of DPI's training-device on inhalation technique and clinical
           efficacy in asthmatics

    • Authors: Mina Nicola; Ahmed A. Elberry; Ossama M Sayed; Raghda R.S. Hussein; Mohamed E.A. Abdelrahim
      Abstract: Publication date: Available online 20 October 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mina Nicola, Ahmed A. Elberry, Ossama M Sayed, Raghda R.S. Hussein, Mohamed E.A. Abdelrahim
      The aim of this work was to study the effect of using training device (In-Check DIAL) along with traditional dry powder inhaler (DPI) counseling on inhalation technique and pulmonary functions test (PFT) in asthmatics. Adult asthmatics >18years old were recruited in 3months study of investigation and training. They were divided into control and investigation groups. DPI inhalation technique was checked and mistakes were noted and corrected at every monthly visit. Their peak expiratory flow and forced expiratory volume in 1second as percentage of forced vital capacity were checked at each visit followed by showing patients the correct inhalation technique and how to use In-Check DIAL (investigation group). 29 patients (14 females) and 57 patients (30 females) in control and investigation groups respectively completed the study. Mean number of mistakes was significantly decreased (p<0.001) as the counseling session increased in both groups. Significant decrease in crucial mistake (inhalation quickly and forcefully until complete filling up of the lungs) that was very hard to be learned via only verbal counseling was noticed after the addition of In-Check DIAL. The improvement of the PFT results were significant from the second visit in the investigation group (p<0.05) and from the third visit in the control group (p<0.001). The decrease in the rate of rescue medication consumption was faster in investigation group than control group. Using training device along with verbal counseling has proven a beneficial role in inhalation technique resulting in optimum dosage delivery and yielding reasonable improvement in PFT.

      PubDate: 2017-10-26T09:42:46Z
      DOI: 10.1016/j.bjbas.2017.10.005
       
  • Antibacterial and anti-hyperlipidemic activities of the green alga
           Cladophora koeiei from Ad Dammam Seashore

    • Authors: Neveen Abdel-Raouf; Nouf Mohammad Al-Enazi; Ibraheem Borie Mohammad Ibraheem; Reem Mohammed Alharbi; Manal Mohammed Alkhulaifi
      Abstract: Publication date: Available online 12 October 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Neveen Abdel-Raouf, Nouf Mohammad Al-Enazi, Ibraheem Borie Mohammad Ibraheem, Reem Mohammed Alharbi, Manal Mohammed Alkhulaifi
      In the present investigation, an antihyperlipidemic activity of Cladophora koeiei ethanol extract against six pathogenic bacteria was conducted. Also, we evaluate the activity of the alga extract against hyperlipedemia in the administrated albino rates through measuring the blood lipid profiles [triglycerides (TG), total cholesterol (TC), low-density lipoprotein (LDL-C), high-density lipoprotein cholesterol (HDL-C), cholesterol] and induced hepatic damage by measuring the contents of creatinine, total proteins, blood urea nitrogen (BUN), albumin and globulin and diagnostic marker enzymes such as aspartate aminotransaminase (AST) and alanine aminotransaminase (ALT). Alga extract proved efficient activity against the tested bacteria ranged between medium and high suppression action. Results revealed also, the efficiency of C. koeiei extract in the decreasing the triglycerides (TG), total cholesterol (TC), low-density lipoproteins (LDL-C), blood urea nitrogen (BUN) and creatinine caused by alcohol. However, the treatment by alga extract exhibits high-density of lipoproteins (HDL-C) (beneficial), total protein, albumin, and globulins. Also, the algal treatments masking the lethal effects caused by harmful alcohol from raising the rate of enzymes ALT, AST, which returned to the normal state in the groups treated with alga extract. Our findings provide the evidence that new natural antioxidant substances can be present in the C. koeiei extract and hence this alga proves to be effective as a source for therapeutic agents.

      PubDate: 2017-10-19T06:19:45Z
      DOI: 10.1016/j.bjbas.2017.10.002
       
  • Rapid Biosynthesis of Silver Nanoparticles Using the marine red alga
           Laurencia catarinensis and their characterization

    • Authors: Neveen Abdel-Raouf; Reem Mohammed Alharbi; Nouf Mohammad Al-Enazi; Manal Mohammed Alkhulaifi; Ibraheem Borie Mohammad Ibraheem
      Abstract: Publication date: Available online 12 October 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Neveen Abdel-Raouf, Reem Mohammed Alharbi, Nouf Mohammad Al-Enazi, Manal Mohammed Alkhulaifi, Ibraheem Borie Mohammad Ibraheem
      Bio-synthesis of AgNPs (silver nanoparticles) by using of the dry and solvent extract of red marine alga Laurencia catarinensis was conducted in the present work. Characterizations of the formed AgNPs was approved by UV-Visible Spectroscopy, Transmission Electron Microscopy, Dynamic Light Scattering and finally by Fourier Transform Infrared spectroscopy. We achieved the synthesis of AgNPs by the reduction of aqueous solutions of AgNO3 with the powder and extract of Laurencia catarinensis. Bio-synthesis of Ag nanoparticles was confirmed by visual inspection. The obtained algal nanoparticles were characterized by highly stable formation, short time of the biogenic process (2min-3hr), small size (39.41–77.71 nm) with several shapes (spherical, triangular, rectangle, polyhedral and hexagonal).

      PubDate: 2017-10-19T06:19:45Z
      DOI: 10.1016/j.bjbas.2017.10.003
       
  • The heat transfer enhancement techniques and their Thermal Performance
           Factor

    • Authors: Chirag Maradiya; Jeetendra Vadher; Ramesh Agarwal
      Abstract: Publication date: Available online 5 October 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Chirag Maradiya, Jeetendra Vadher, Ramesh Agarwal
      Heat transfer devices have been used for conversion and recovery of heat in many industrial and domestic applications. Over five decades, there has been concerted effort to develop design of heat exchanger that can result in reduction in energy requirement as well as material and other cost saving. Heat transfer enhancement techniques generally reduce the thermal resistance either by increasing the effective heat transfer surface area or by generating turbulence. Sometimes these changes are accompanied by an increase in the required pumping power which results in higher cost. The effectiveness of a heat transfer enhancement technique is evaluated by the Thermal Performance Factor which is a ratio of the change in the heat transfer rate to change in friction factor. Various types of inserts are used in many heat transfer enhancement devices. Geometrical parameters of the insert namely the width, length, twist ratio, twist direction, etc. affect the heat transfer. For example counter double twisted tape insert has TPF of more than 2 and combined twisted tape insert with wire coil can give a better performance in both laminar and turbulent flow compared to twisted tape and wire coil alone. In many cases, roughness gives better performance than the twisted tape as seen in case of flow with large Prandtl Number. The artificial roughness can be developed by employing a corrugated surface which improves the heat transfer characteristics by breaking and destabilizing the thermal boundary layer. This paper provides a comprehensive review of passive heat transfer devices and their relative merits for wide variety of industrial applications.

      PubDate: 2017-10-19T06:19:45Z
      DOI: 10.1016/j.bjbas.2017.10.001
       
  • Adulticidal and Repellent Activities of Some Botanical Oils against
           Malaria Mosquito: Anopheles gambiae (Diptera: Culicidae)

    • Authors: Afolabi O. Joseph; Simon-Oke I. Adepeju; Elufisan O. Oluwaloleyeayemi; Oniya M. Oladipo
      Abstract: Publication date: Available online 20 September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Afolabi O. Joseph, Simon-Oke I. Adepeju, Elufisan O. Oluwaloleyeayemi, Oniya M. Oladipo
      The study is undertaken to determine the adulticidal efficacy and repellent activity of different solvent extracts of Ocimum caninum, Ocimum gratissimum, Chromolaena odorata and Datura stramonium against adult Anopheles gambiae. The extracts showed adulticidal activity at LC50 (0.82-4.58mg/l) and LC90 (2.38-8.33mg/l). The highest mortality was observed in Ocimum gratissimum and Datura stramonium with the LC50 and LC90 values of 2.35mg/l, 4.75ml/l and 0.82mg/l, 2.38mg/l respectively. Meanwhile, the lowest adulticidal activity was recorded in Chromolaena odorata with the lowest LC50 (4.52mg/l) and LC90 (8.32mg/l). The repellent efficacy was determined against the mosquitoes at five concentrations viz 1.0, 2.0, 3.0, 4.0 and 5.0 mg/l under laboratory condition (28±2°C, 75±5% RH, 12L: 12D photoperiod). The results showed complete protections of 90mins for Ocimum caninum, 120mins for Ocimum gratissimum, 30mins for Chromolaena odorata and 120mins for Datura stramonium at 5mg/l of the extracts respectively. It was observed that D. stramonium and O. gratissimum provided highest protection (120mins) against Anopheles gambiae while the least protection (30s) was observed in Chromolaena odorata at 5mg/l. The results of the study showed that all the crude extracts with the exception of Chromolaena odorata were potential botanicals for confirming protection on the exposed parts of human body against Anopheles gambiae for at least 90mins and as such can be included in integrated vector management to reduce malaria infection in endemic areas.

      PubDate: 2017-09-26T18:40:07Z
      DOI: 10.1016/j.bjbas.2017.09.004
       
  • Synergistic effect of ACE and AGT genes in Coronary Artery Disease

    • Authors: Ibrahim H. Borai; Nahla S. Hassan; Olfat G. Shaker; Esmat Ashour; Mohammed El Badrawy; Olfat M. Fawzi; Lamiaa Mageed
      Abstract: Publication date: Available online 18 September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Ibrahim H. Borai, Nahla S. Hassan, Olfat G. Shaker, Esmat Ashour, Mohammed El Badrawy, Olfat M. Fawzi, Lamiaa Mageed
      Polymorphisms of the renin-angiotensin system genes influence the pathogenesis of atherosclerosis and are connected with heart diseases. We explore the potential associations of ACE (I/D) and AGT (M235T) gene polymorphisms with coronary artery disease (CAD). A total of one hundred and twenty Egyptian patients (Sixty with CAD and sixty without CAD) and fifty healthy control subjects were included in the study. Genotyping of ACE (I/D) and AGT (M235T) were analyzed by the polymerase chain reaction (PCR) technique. Serum lipid profiles (total cholesterol, triglyceride, HDL-C) were measured by the enzymatic colorimetric method. Our data showed that the ACE D allele frequency (P<0.0001; odds ratio [OR] =2.538, 95% confidence interval [CI] =1.468-4.388), DD genotype (P<0.0001, OR=0.239, 95% CI=0.066-0.866), the frequency of AGT T allele (P<0.0001, OR= 2.915, 95% CI= 1.666-5.097) and TT genotype (P<0001, OR=0.316, 95% CI=0.078-1.280) were significantly more prevalent among CAD patients and may be predisposing to CAD. We further found that the concomitant presence of the ACE-DD and AGT-TT genotypes increased the risk of CAD (P=0.017, OR=0.120, 95% CI=0.042-0.347).This study demonstrated the contribution of ACE (I/D) and AGT (M235T) gene polymorphisms individually or in combination to the presence of CAD risk in the Egyptian population. The ACE D allele and AGT T allele may be predictive in individuals at risk of developing CAD.

      PubDate: 2017-09-20T15:03:13Z
      DOI: 10.1016/j.bjbas.2017.09.003
       
  • Clinico-radiographic and histopathologic evaluation of iliac shaft
           fracture in dogs (An experimental study)

    • Authors: M.Z. Fathy; G.H. Ragab; M.M. Seif; S.M. Gadallah; Salah Deeb; Nesreen M. Safwat
      Abstract: Publication date: Available online 14 September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): M.Z. Fathy, G.H. Ragab, M.M. Seif, S.M. Gadallah, Salah Deeb, Nesreen M. Safwat
      The pelvic region has a great importance as it is the connecting ring between the hind limbs and the trunk as well as having special shape. The present study was conducted on 15 adult, mongrel male dogs aged 2-3 years and weighted 15 – 20 kg. Iliac shaft fracture was induced experimentally, and the fractured ilium was fixed by Dynamic Compatable Plate (DCP). Fracture healing was evaluated clinically, radiologically and histopahologically. The animals were partially-weight bearing on the limb of operated side 4th day post-operatively and they were full-weight bearing within 17th days post-operatively. The gait was varied from occasional lameness to full function at the 21-28th post-operatively. The results of this study was conducted along 16 weeks confirmed that the internal fixation for fractured ilium using a bone plate and screws had a good fixation and healing and all animals returned to normal gait within short time.

      PubDate: 2017-09-15T14:59:21Z
      DOI: 10.1016/j.bjbas.2017.09.001
       
  • Antitumor activity of synthesized and characterized Cu(II), Ni(II) and
           Co(II) complexes of hydrazone-oxime ligands derived from 3-(hydroxyimino)
           butan-2-one

    • Authors: Fathy A. El-Saied; Tarek A. Salem; Mohamad M.E. Shakdofa; Ahmed N. Al-Hakimi; Ahmed S. Radwan
      Abstract: Publication date: Available online 9 September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Fathy A. El-Saied, Tarek A. Salem, Mohamad M.E. Shakdofa, Ahmed N. Al-Hakimi, Ahmed S. Radwan
      Mononuclear and binuclear metal complexes of hydrazone oxime resulted from the condensation of acetohydrazide and pyridyl hydrazide with 3-(hydroxyimino) butan-2-one were prepared. All compounds were characterized using elemental, spectral and thermal analyses, as well as magnetic moment and molar conductance measurements. The ligands acted as neutral/monobasic bidentate, monobasic tridentate and dibasic tetradentate ligands bonded to the metal ions via azomethine nitrogen or oxime oxygen atoms and enolic carbonyl oxygen or pyridine nitrogen atom. The spectral and magnetic studies of the complexes showed that exhibit either distorted octahedral, square planer or tetrahedral geometry. Newly complexes were tested for their anti-proliferative activity in vitro against three human cell lines; MCF-7, Hep-G2 and HL-60. The cytotoxic action of the complexes was determined and compared to that of the anticancer drug doxorubicin. Results of cytotoxicity activities indicated that the compound (6) has a wide range of cytotoxicity against the three cell lines in concentration ranges as that of doxorubicin. It shows more cytotoxic against MCF-7 (IC50= 1.8 μM) and HL-60 (IC50= 10.6 μM) cancer cell lines. Compounds (H2L1) and (11) exhibited higher cytotoxic activities rather than doxorubicin against MCF-7 and HL-60 cell line. Compounds (2) and (11) are 3.1 and 2.1 times more active than doxorubicin; respectively, against HL-60 cell line.

      PubDate: 2017-09-15T14:59:21Z
      DOI: 10.1016/j.bjbas.2017.09.002
       
  • Interactive Approach for Multi-level Multi-objective Fractional
           Programming Problems with Fuzzy parameters

    • Authors: M.S. Osman; O.E. Emam; M.A. Elsayed
      Abstract: Publication date: Available online 9 September 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): M.S. Osman, O.E. Emam, M.A. Elsayed
      In this paper, an interactive approach for solving multi-level multi-objective fractional programming (ML-MOFP) problems with fuzzy parameters is presented. The proposed interactive approach makes an extended work of Shi and Xia (1997). In the first phase, the numerical crisp model of the ML-MOFP problem has been developed at a confidence level without changing the fuzzy gist of the problem. Then, the linear model for the ML-MOFP problem is formulated. In the second phase, the interactive approach simplifies the linear multi-level multi-objective model by converting it into separate multi-objective programming problems. Also, each separate multi-objective programming problem of the linear model is solved by the ∊-constraint method and the concept of satisfactoriness. Finally, illustrative examples and comparisons with the previous approaches are utilized to evince the feasibility of the proposed approach.

      PubDate: 2017-09-15T14:59:21Z
      DOI: 10.1016/j.bjbas.2017.08.005
       
  • Design Of Twisted Tape Turbulator At Different Entrance Angle For Heat
           Transfer Enhancement In A Solar Heater

    • Authors: Suvanjan Bhattacharyya; Himadri Chattopadhyay; Ayan Haldar
      Abstract: Publication date: Available online 31 August 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Suvanjan Bhattacharyya, Himadri Chattopadhyay, Ayan Haldar
      Numerical investigation of heat transfer characteristics in a tube fitted with inserted twisted tape swirl generator is performed. The twisted tapes are separately inserted from the tube wall. The configuration parameters include the, entrance angle (α) and pitch (H). Investigations have been done in the range of α = 180o, 160o and 140o with Reynolds number varying between 100 to 20,000. In this paper, transition - SST model which can predict the transition of flow regime from laminar through intermittent to turbulent has been utilized for numerical simulations. The computational results are in good agreement with experimental data. The results show that higher entrance angle yields a higher heat transfer value. The using of single twist twisted tape supplies considerable increase on heat transfer and pressure drop when compared with the conventional twisted tapes. A large data set has been generated for heat transfer and thermal-hydraulic performance which is useful for the design of solar thermal heaters and heat exchangers.

      PubDate: 2017-09-02T14:50:12Z
      DOI: 10.1016/j.bjbas.2017.08.003
       
  • In silico binding affinity studies of N-9 substituted
           6-(4-(4-propoxyphenyl)piperazin-1-yl)-9H-purine derivatives-Target for
           P70-S6K1 & PI3K- δ kinases

    • Authors: Manjunath G. Sunagar; P. Aravind; Supreet Gaonkar; K.S. Devaraju; Shrinivas D. Joshi; Sheshagiri R. Dixit; B.M. Harish; Imtiyaz Ahmed M. Khazi
      Abstract: Publication date: Available online 31 August 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Manjunath G. Sunagar, P. Aravind, Supreet Gaonkar, K.S. Devaraju, Shrinivas D. Joshi, Sheshagiri R. Dixit, B.M. Harish, Imtiyaz Ahmed M. Khazi
      P70-S6K1 & PI3K- δ kinases are identified to be involved in many physiological processes associated with cancer, therefore many of the inhibitors being designed to target these kinases are in clinical trials. In the current study we have exploited the N-9 substituted 6-(4-(4-propoxyphenyl) piperazin-1-yl)-9H-purine derivatives for their inhibitory properties with the above kinases. We have used an in silico docking study with seventeen purine derivatives for their binding affinity calculations. The binding affinities of these small molecules with P70-S6K1 & PI3K-δ were performed using AutoDock Vina. Among all the compounds, PP16 showed highest binding affinity of -14.7 kcal/mol with P70-S6K1 kinase & -17.2 kcal/mol with PI3K-δ kinases as compared to the molecules under clinical trials (PF-4708671 & IC-87114). Docking studies revealed that N-9 coumarine substituted purine derivative could be one of the potential ligands for the inhibition of P70-S6K1 & PI3K-δ kinases. Hence, this compound can be further investigated by in vitro and in vivo experiments for further validation.
      Graphical abstract image

      PubDate: 2017-09-02T14:50:12Z
      DOI: 10.1016/j.bjbas.2017.08.004
       
  • Synthesis and antibacterial activity studies of 2,4-di substituted furan
           derivatives

    • Authors: Sireesha Malladi; R. Venkata Nadh; K. Suresh Babu; P. Suri Babu
      Abstract: Publication date: Available online 15 August 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Sireesha Malladi, R. Venkata Nadh, K. Suresh Babu, P. Suri Babu
      2,4 disubstitiuted furan derivatives (8A–8M) were prepared from furan-4-carboxylic acid ethyl ester (1). Antibacterial activity of new 2,4 di substituted furan derivatives was studied against Gram (+) and Gram (−) bacteria. 8F, 8E, 8D and 8J were found to be effective against Gram (−) bacteria whereas, 8A and 8L were effective against Gram (+) bacteria. Least MIC value was found as 100µg/ml against Escherichia coli (for 8D and 8F), and Proteus vulgaris (for 8E and 8F). Antibacterial activity is correlated with different substituents. Products exhibited better antibacterial activities especially towards Streptococcus pyogenes, Proteus vulgaris, and Escherichia coli.
      Graphical abstract image

      PubDate: 2017-09-02T14:50:12Z
      DOI: 10.1016/j.bjbas.2017.08.001
       
  • Role of marine macroalgae in plant protection & improvement for
           sustainable agriculture technology

    • Authors: Seham M. Hamed; Amal A. Abd El-Rhman; Neveen Abdel-Raouf; Ibraheem B.M. Ibraheem
      Abstract: Publication date: Available online 14 August 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Seham M. Hamed, Amal A. Abd El-Rhman, Neveen Abdel-Raouf, Ibraheem B.M. Ibraheem
      Marine macroalgae are plant-like organisms with simple internal structures that generally live in coastal areas. They mainly includedifferent communities of red, brown and green macroalgae. Marine macroalgae commonly occupy intertidal and sublittoral-to-littoral zones on rocks and other hard substrata. They are considered to be an excellent natural biosource in different aspects of agricultural fields. They have great proficiency in improving soil physical and chemical properties. Marine macroalgae are also characterized by producing a large array of biologically active biocidal substances against plant-infecting pathogens. Unfortunately, most available literatures on marine macroalgae and their derivatives mainly focused on their pharmaceutical applications but their potential utilization in sustainable agriculture development is still often regarded asa secondary goal. However, a relatively considerable dataset on marine macroalgae showed that they could play a major role in plant protection and improvement. This review summarizes different aspects of potential macroalgal applications in agriculture. Commercial production and exploitation of specific compounds with interesting biotechnological importance from marine macroalgae including microbicides, nematicides, insecticides, biofertilizers, biostimulators and soil conditioners are highlighted and discussed in detail. Bioactive compounds like fatty acids (in particular polyunsaturated fatty acids (PUFAs), proteins (amino acids), bioflavonoids, sulfated polysaccharides, carotenoids, polyphenols and carbohydrates are considered to have bactericidal, antiviral and fungicidal effects against some plant-infecting pathogens. These biocontrol agents provide multiple benefits and act as useful pointers for improving cultivation practices in diverse habitats. Marine macroalgae can be generally considered as promising multifunctional bioinoculants and ecofriendly environmental tools in recent trends of organic farming.

      PubDate: 2017-09-02T14:50:12Z
      DOI: 10.1016/j.bjbas.2017.08.002
       
  • Detection of Methicillin Resistant and Toxin-Associated Genes in
           Staphylococcus aureus

    • Authors: Cajethan Ezeamagu; Irene Imanatue; Margaret Dosunmu; Adebola Odeseye; Glory Baysah; Daniel Aina; Foluke Odutayo; Grace Mensah-Agyei
      Abstract: Publication date: Available online 1 August 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Cajethan Ezeamagu, Irene Imanatue, Margaret Dosunmu, Adebola Odeseye, Glory Baysah, Daniel Aina, Foluke Odutayo, Grace Mensah-Agyei
      Methicillin-resistant Staphylococcus aureus is a problem in both healthcare institutions and community settings. This is due to its multi-drug resistant challenges. Hence, this study assessed the prevalence of methicillin resistant gene (mecA), exfoliative toxin (eta and etb) and toxic shock syndrome (tsst-1) genes in S. aureus isolated from clinical samples. A total of 120 clinical samples of patients (urine, high vagina swab (HVS), semen, wound swab, sputum and urethral swab) from a hospital laboratory were obtained. S. aureus was isolated and then identified with API-staph kit. Antibiotic susceptibility of the isolates was determined by agar diffusion while PCR was used to detect the presence of mecA and toxin-associated genes. Fifty S. aureus isolates were obtained at frequencies of 26(52%), 12(24%), 4(8%), 3(6%), 3(6%) and 2(4%) from the HVS, urine, semen, wound, sputum and urethral swab samples respectively. All the isolates of S. aureus were resistant to the antibiotics used in this study. MecA, tsst-1, eta and etb were detected in 19(38%), 7(14%), 3(6%) and 2(4%) of the isolates respectively. The prevalence of MRSA and its resistance pattern observed in this study was a signal that the health-care workers and the general public are at risk.

      PubDate: 2017-08-03T13:24:21Z
      DOI: 10.1016/j.bjbas.2017.07.010
       
  • The genus Vitex: An Overview of Iridoids as Chemotaxonomic Marker

    • Authors: M Bello Oluwasesan; Ahmed A. Zaki; Aloko Sinmisola; Pius S. Fasinu; M Bello Oluwatoyin; Usman L. Ajao; Oguntoye S. Olubunmi
      Abstract: Publication date: Available online 23 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): M Bello Oluwasesan, Ahmed A. Zaki, Aloko Sinmisola, Pius S. Fasinu, M Bello Oluwatoyin, Usman L. Ajao, Oguntoye S. Olubunmi
      In our continuing work on Vitex genus, the phytochemical investigation of leaves of Vitex grandifolia led to the isolation of two iridoids known in the literature as agnuside and bartsioside. The chemical structures were characterized by combined spectroscopic analysis. These compounds were isolated from this specie for the first time, this study give evidence to iridoids as chemotaxonomic marker and their constitutive presence has been reported in a number of genera in the family Lamiaceae. Iridoids have been isolated from nineteen species belonging to genus Vitex from Lamiaceae especially aucubin and agnuside. In addition to the utilization of morphological features of plants belonging to this genus, these compounds may be useful chemotaxonomic markers to aid taxonomic identification. This work evaluates and describes the distribution of iridoids in Vitex species to further establish this claim with structures of the iridoids found in this genus.

      PubDate: 2017-07-24T02:10:59Z
      DOI: 10.1016/j.bjbas.2017.07.004
       
  • A practical and powerful approach to potential KdV and Benjamin equations

    • Authors: Turgut Ak; Sharanjeet Dhawan
      Abstract: Publication date: Available online 22 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Turgut Ak, Sharanjeet Dhawan
      By making use of reduced differential transform method (RDTM), we analyse two model problems: the potential KdV equation which is believed to replicate tsunami waves and the Benjamin equation which is used in the analysis of long waves in shallow water. Our principal focus is to investigated computationally the travelling wave solutions of both the equations using RDTM. These solutions are going to be extremely useful for explaining various other nonlinear phenomena arising in various dynamical systems.

      PubDate: 2017-07-24T02:10:59Z
      DOI: 10.1016/j.bjbas.2017.07.008
       
  • Vernonia amygdalina: a folkloric herb with anthelminthic properties

    • Authors: Ifeoluwa T. Oyeyemi; Akinbiyi A. Akinlabi; Aderiike Adewumi; Abimbola O. Aleshinloye; Oyetunde T. Oyeyemi
      Abstract: Publication date: Available online 21 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Ifeoluwa T. Oyeyemi, Akinbiyi A. Akinlabi, Aderiike Adewumi, Abimbola O. Aleshinloye, Oyetunde T. Oyeyemi
      Vernonia amygdalina is a widely grown shrub plant in Africa consumed as vegetable and has high medicinal value. It has gained wide application in the treatment and management of various diseases. The leaves are useful components for herbal medicine constitution. The plant’s activities is a result of diverse bioactive compounds isolated from the different parts of the plant. These metabolites have specifically been efficacious against parasites especially worms. The mechanisms of activities include paralysis of worm, interference with energy generation and impairment with nutrient absorption, motility, and reproduction. The lack of considerable toxicity associated with the plant makes it a choice for further drug discovery. Effort should be made towards standardizing the extract(s) of V. amygdalina for use in alternative medicine for treatment of helminth-related diseases.

      PubDate: 2017-07-24T02:10:59Z
      DOI: 10.1016/j.bjbas.2017.07.007
       
  • Prevalence of Porcine Reproductive and Respiratory Syndrome Virus and
           Porcine Parvovirus Antibodies in Commercial Pigs, Southwest Nigeria

    • Authors: Comfort O. Aiki-Raji; Adebowale I. Adebiyi; John O. Abiola; Daniel O. Oluwayelu
      Abstract: Publication date: Available online 21 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Comfort O. Aiki-Raji, Adebowale I. Adebiyi, John O. Abiola, Daniel O. Oluwayelu
      Porcine reproductive and respiratory syndrome virus (PRRSV) and porcine parvovirus (PPV) infections cause significant economic losses to the pig industry and are considered the most economically important viral diseases of intensive swine production. Despite numerous reports on both diseases in several countries worldwide, the status of PRRSV and PPV in Nigeria remains largely unknown. Thus, a serological survey was conducted to determine the prevalence of PRRSV and PPV infections in pigs in Southwest Nigeria. Using commercial ELISA kits, 368 pig sera were screened for antibodies against PRRSV (types I and II) and PPV.Significantly higher antibody prevalence was obtained for PRRSV (53.8%) compared to PPV (36.1%). Since there is no vaccination against both diseases in the country, the findings of this study suggest that PRRSV and PPV are present in the pig population in southwest Nigeria. There should be continuous monitoring of pigs for these diseases in Nigeria since both viruses are associated with major economic losses in the swine industry, affecting all stages of production. This will help to ascertain the actual burden and increase awareness of both diseases to facilitate early detection in order to institute appropriate control measures in the country.

      PubDate: 2017-07-24T02:10:59Z
      DOI: 10.1016/j.bjbas.2017.07.006
       
  • A review on Quinoline hydrazone derivatives as a new class of potent
           antitubercular and anticancer agents

    • Authors: Mustapha C. Mandewale; Udaysinha C. Patil; Supriya V. Shedge; Uttam R. Dappadwad; Ramesh S. Yamgar
      Abstract: Publication date: Available online 20 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mustapha C. Mandewale, Udaysinha C. Patil, Supriya V. Shedge, Uttam R. Dappadwad, Ramesh S. Yamgar
      Tuberculosis (TB) and Cancer remains a global public health problem in recent years. There is an urgent need for the screening of new bioactive molecules with new targets and with a different mechanism of action. Among heterocyclic compounds, compounds with Quinoline core gained much importance in medicinal chemistry. Quinoline hydrazone scaffold plays an important role in anti-tuberculosis and anticancer drug development as their derivatives have shown outstanding results. This broad spectrum of biological and biochemical activities has been further assisted by the synthetic flexibility of quinoline, which permits the invention of a large number of structurally varied hydrazone derivatives and their metal complexes. In order to pave the way for future advanced research, there is a need to collect and analyze the latest information available so far in this promising area. In this review, we have compiled and discussed the published reports specifically on anti-tuberculosis and anticancer potential of quinoline hydrazone derivatives. It is hoped that this review will be helpful for researchers in developing a new view in the search for rational designs of more active and less toxic quinoline-based anti-TB and anticancer drugs.
      Graphical abstract image

      PubDate: 2017-07-24T02:10:59Z
      DOI: 10.1016/j.bjbas.2017.07.005
       
  • Evaluation of the epidural analgesic effect of Nalbuphine, Lidocaine and
           Nalbuphine – Lidocaine combination in bucks

    • Authors: G.A. Ragab; M.Z. Fathy
      Abstract: Publication date: Available online 14 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): G.A. Ragab, M.Z. Fathy
      Nalbuphine is a lipophilic opioid which could be used subcutaneously, intramuscularly, intravenously and epidurally in human, dogs and equine but not used in bucks until yet. The aim of the existing study was to compare the analgesic effect of Nalbuphine, Lidocaine and Nalbuphine – Lidocaine combination injected epidurally in bucks. Fifteen adult apparently healthy bucks were used. The animals were randomly divided into three groups (five animals in each one); group (1) was injected with Nalbuphine HCl at a dose 3mg/kg, group (2) was injected with Lidocaine HCl 2% at a dose 2.5mg / kg. Finally, group (3) was injected with Nalbuphine-Lidocaine combination at a dose (1.5mg /kg and 1.25mgkg, resp.) to evaluate the analgesic effect of each treatment. Onset and duration of analgesia were recorded after each treatment. Respiratory rate, heart rate, rectal temperature and biochemical parameters were recorded for each treatment. The results revealed that, the onset and duration of analgesia respectively were 12±2min and 200±4min in group (1), 6±1min and 80±3min in group (2) and 8±2min and 120±5min in group (3). In Nalbuphine group, No ataxia was observed while mild ataxia was observed in Nalbuphine-Lidocaine combination group but in Lidocaine treated group, sever ataxia was recorded. Heart rate increased at 90–120 and respiratory rate rectal temperature had no any significantly differentiation from baseline of any treatment. Biochemical parameters returned to basal levels through three hours after all treatments. In conclusion, Nalbuphine – lidocaine combination is useful to perform surgical operations of long duration and had effective analgesia in bucks.

      PubDate: 2017-07-24T02:10:59Z
      DOI: 10.1016/j.bjbas.2017.07.001
       
  • Effect of cypermethrin on the ovarian activity and its impact on fertility
           and pubertal onset of offspring

    • Authors: Nada M.H. Al-Hamdani; H.N. Yajurvedi
      Abstract: Publication date: Available online 10 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Nada M.H. Al-Hamdani, H.N. Yajurvedi
      Oral (by gavage) administration of cypermethrin (CYP), (3 doses; 1.38, 2.76 and 5.52 mg/kg body weight) to female mice for two durations (6 weeks and 12 weeks), caused significant reduction in the number of estrous cycles per month, serum levels of estradiol, total number of healthy ovarian follicles and number of corpora lutea whereas there was an increase in number of atretic follicles of all categories compared to controls. Mice of all treated groups after 6 weeks treatment showed 100% fertility. It was 80% in low and medium doses and 60% in high dose treatment after 12 weeks. There was a significant delay in the onset of puberty and reduction in number of estrous cycles of progeny of medium and high dose CYP treated mice mated with normal males. Number of estrous cycles per month, healthy follicles, corpora lutea and serum levels of estradiol, were not reversible within 6 weeks after cessation of medium and high dose treatment for 12 weeks. The study first time reveals that reversibility of the reproductive toxic effects of CYP depends on quantum and duration of exposure.

      PubDate: 2017-07-12T01:22:09Z
      DOI: 10.1016/j.bjbas.2017.07.003
       
  • A fuzzy logic based promethee method for material selection problems

    • Authors: Muhammet Gul; Erkan Celik; Alev Taskin Gumus; Ali Fuat Guneri
      Abstract: Publication date: Available online 8 July 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Muhammet Gul, Erkan Celik, Alev Taskin Gumus, Ali Fuat Guneri
      Material selection is a complex problem in the design and development of products for diverse engineering applications. This paper presents a fuzzy PROMETHEE (Preference Ranking Organization Method for Enrichment Evaluation) method based on trapezoidal fuzzy interval numbers that can be applied to the selection of materials for an automotive instrument panel. Also, it presents uniqueness in making a significant contribution to the literature in terms of the application of fuzzy decision-making approach to material selection problems. The method is illustrated, validated, and compared against three different fuzzy MCDM methods (fuzzy VIKOR, fuzzy TOPSIS, and fuzzy ELECTRE) in terms of its ranking performance. Also, the relationships between the compared methods and the proposed scenarios for fuzzy PROMETHEE are evaluated via the Spearman’s correlation coefficient. Styrene Maleic Anhydride and Polypropylene are determined optionally as suitable materials for the automotive instrument panel case. We propose a generic fuzzy MCDM methodology that can be practically implemented to material selection problem. The main advantages of the methodology are consideration of the vagueness, uncertainty, and fuzziness to decision making environment.

      PubDate: 2017-07-12T01:22:09Z
      DOI: 10.1016/j.bjbas.2017.07.002
       
  • Preparation of environmental friendly phenol-formaldehyde wood adhesive
           modified with kenaf lignin

    • Authors: M. Hazwan Hussin; Hau Han Zhang; Nurul Azila Aziz; Noraini Abd Samad; Abbas Hassan Faris; Mohamad Nasir Mohamad Ibrahim; Anwar Iqbal; Ahmad Faiz Abdul Latip; M.K. Mohamad Haafiz
      Abstract: Publication date: Available online 27 June 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): M. Hazwan Hussin, Hau Han Zhang, Nurul Azila Aziz, Noraini Abd Samad, Abbas Hassan Faris, Mohamad Nasir Mohamad Ibrahim, Anwar Iqbal, Ahmad Faiz Abdul Latip, M.K. Mohamad Haafiz


      PubDate: 2017-07-03T01:16:25Z
      DOI: 10.1016/j.bjbas.2017.06.004
       
  • Optimization of paclitaxel loaded poly (ε-caprolactone) nanoparticles
           using box behnken design

    • Authors: Nandhakumar Sathyamoorthy; Dhanaraju Magharla; Pavankumar Chintamaneni; Sundar Vankayalu
      Abstract: Publication date: Available online 16 June 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Nandhakumar Sathyamoorthy, Dhanaraju Magharla, Pavankumar Chintamaneni, Sundar Vankayalu
      Optimization is a critical process in the development of nanoparticles to apprehend the formulation variables and quality attributes. The purpose of this study was to evaluate the influence of formulation variables viz., drug/polymer ratio (A), surfactant concentration (B) and ratio of volume of internal to external phase (C) on the dependent variables (particle size, % EE and zeta potential) of paclitaxel loaded poly (ε-caprolactone) nanoparticles using Box-Behnken design. The nanoparticles were fabricated using emulsion-solvent evaporation technique. The generated polynomial equations, contour plots and response surface plots of the design space were used to analyze the relationship between independent variables and the observed response. An optimal batch was formulated with selected variables (A: +1 level, B: 0 level, C: -1 level) and the prepared nanoparticles were found to have particle size 215.6 µm, zeta potential -7.52 mV and % drug entrapment 86.78%. The observed responses are in close agreement with the predicted values. NPs were spherical with a smooth surface as revealed by morphological studies and the drug-polymer compatibility was established using FTIR and thermal analysis. The drug was released from the NPs in a biphasic pattern with an initial burst release (32.1 %) followed by sustained release (53 %) at the end of 5 d. The in vitro cell cytotoxicity studies on MCF-7 cells showed that the NPs held superior tumour inhibition ability. The results encourage the application of Box-Behnken design for the optimization of critical variables and fabrication of nanoparticles with desirable properties for drug delivery.

      PubDate: 2017-06-16T22:09:06Z
      DOI: 10.1016/j.bjbas.2017.06.002
       
  • Antileishmanial potential of medicinal plant extracts from the North-West
           of Morocco

    • Authors: Abdelhakim Bouyahya; Abdeslam Et-Touys; Nadia Dakka; Hajiba Fellah; Jamal Abrini; Youssef Bakri
      Abstract: Publication date: Available online 15 June 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Abdelhakim Bouyahya, Abdeslam Et-Touys, Nadia Dakka, Hajiba Fellah, Jamal Abrini, Youssef Bakri
      The aim of this study is to evaluate the antileishmanial activity of selected medicinal plants from the North-West of Morocco. Plant extracts were prepared by maceration using methanol, ethanol, and n-hexane. The antileishmanial activity was evaluated against Leishmania major, Leishmania tropica, and Leishmania infantum using MTT (3- (4.5-dimethylthiazol- 2yl)-2.5-diphenyltetrazolium bromide) assay. All plant extracts showed a reducing in cell promastigotes viability with variability depending on tested strains and type of extracts. The n-hexane extract showed the highest antileishmanial activity and L. infantum was the most sensitive parasite. The best growth inhibition was observed with Cistus crispus n-hexane extract against L. major (IC50=47.29±2.25 μg/mL), Arbutus unedo n-hexane extract against L. infantum (IC50=64.05±1.44 μg/mL) and Arbutus unedo n-hexane extract against L. tropica (IC50=79.57±2.66 μg/mL). Considering these results, medicinal plants from the North-West of Morocco could constitute a promoter source for antileishmanial compounds.

      PubDate: 2017-06-16T22:09:06Z
      DOI: 10.1016/j.bjbas.2017.06.003
       
  • Spectral thermal cytotoxic and molecular docking studies of
           N'-2-hydroxybenzoyl; pyridine-4-carbohydrazide its complexes

    • Authors: R. Mohammed Shafeeulla; G. Krishnamurthy; H.S. Bhojynaik; H.P. Shivarudrappa; Yallappa Shiralgi
      Abstract: Publication date: Available online 13 June 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): R. Mohammed Shafeeulla, G. Krishnamurthy, H.S. Bhojynaik, H.P. Shivarudrappa, Yallappa Shiralgi


      PubDate: 2017-06-16T22:09:06Z
      DOI: 10.1016/j.bjbas.2017.06.001
       
  • Molecular Docking Analysis and Antidiabetic activity of Rifabutin against
           STZ-NA induced diabetes in albino wistar rats

    • Authors: Danish Ahmed; Mohd. Ibrahim Khan; Gaurav Kaithwas; Subhadeep Roy; Swetlana Gautam; Manjari Singh; Uma Devi; Rajnsih Yadav; Jitendra Rawat; Shubhini Saraf
      Abstract: Publication date: Available online 25 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Danish Ahmed, Mohd. Ibrahim Khan, Gaurav Kaithwas, Subhadeep Roy, Swetlana Gautam, Manjari Singh, Uma Devi, Rajnsih Yadav, Jitendra Rawat, Shubhini Saraf
      Computer Aided Drug Design (CADD) molecular docking program used in this study and as a result Rifabutin was retrieved as structurally similar drug molecule to Lixisenatide (A widely used GLP-1 agonist). To afford beneficial reason in-vitro study conducted which too provides a favourable mark for prospective inhibition of α-glucosidase and α-amylase enzyme and thereby evaluated for its antidiabetic potential against Streptozotocin (STZ) and Nicotinamide (NA) induced diabetes in albino wistar rats. Rifabutin demonstrated significant efficacy towards restoring the blood glucose, insulin and distorted lipid profile in the animals treated with STZ-NA. Rifabutin also regulated the inflammatory (Nitric Oxide) and oxidative stress (TBARs, SOD, Catalase, GSH and protein carbonyl) markers in the pancreatic tissue of the STZ-NA treated animals. When scrutinized on the grounds electrocardiographic and heart rate variability (HRV) changes, Rifabutin decreased the heart rate, without much affecting the QRS, QT and QTc interval. Rifabutin was also evident to be less hepatotoxic in comparison to the standard metformin, providing an added advantage as an anti-diabetic agent. The study concluded that the low dose of rifabutin can favourably regulate of the blood glucose and other biochemical paradigms in comparison to high dose of rifabutin.
      Graphical abstract image

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.010
       
  • Heavy metal and Potential Ecological Risk Assessment in sedimentscollected
           from Poombuhar to Karaikal Coast of Tamilnadu using Energy dispersive
           X-ray fluorescence (EDXRF) technique

    • Authors: E. Devanesan; M. Suresh Gandhi; M. Selvapandian; G. Senthilkumar; R. Ravisankar
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): E. Devanesan, M. Suresh Gandhi, M. Selvapandian, G. Senthilkumar, R. Ravisankar
      Heavy metal concentrations in coastal sediments from Poombuhar to Karaikal of South East Coast of Tamilnadu were conducted to evaluate the level of contamination. The metal concentrations were analyzed in sediment samples using Energy dispersive X-ray fluorescence technique. The determined mean metal concentration is in the order of Ca > Ti > K > Al > Fe > Mg > Zn > Ni > Cr > V > Mn > Co The heavy metals contamination in sediments is assessed using pollution indices like Contamination factor (Cf), Contamination Degree (Cd), Modified Degree of Contamination (mCd) and potential contamination index (Cp). The environmental risks of the heavy metals in sediments assessed by the potential ecological risk factor. From the analysis, sediments are polluted by Ti, V, Cr, Mn, Ca and Pb due to anthropogenic activites (fishermen boat activites) in the study area. The results of this study would provide a useful aid for sustainable marine management in the region.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.011
       
  • Impact of Generic Antimalarial or Phyllanthus Amarus and Vitamin
           Co-Administration on Antioxidant Status of Experimental Mice Infested With
           Plasmodium Berghei

    • Authors: Matthew Obaineh Ojezele; Emuesiri Goodies Moke; Innocent Onyesom
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Matthew Obaineh Ojezele, Emuesiri Goodies Moke, Innocent Onyesom
      Oxidative stress is a key factor in malaria pathogenesis, particularly, malaria induced anaemia and pathological changes in some organs in the body. This research aimed at investigating the effect of Phyllanthus amarus seed extract (PASE), chloroquine (CLQ), and artesunate (ATS) used alone and co-administered with vitamin A, B, C, or E on oxidative stress in Plasmodium berghei-infected mice. A total of eighty (80) adult albino male mice infected with P. berghei (NK 65 strain) were randomly allotted to 16 treatment groups, mice in another group (17th group) were uninfected; n=5. Of the treatment groups, fifteen were administered sole generic antimalarials/PASE and combined vitamins A, B, C or E orally for 5 days. Biochemical assay for glutathione peroxidase (GPx), and glutathione reductase (GR) were carried out on the serum. Assay for glutathione peroxidase (GPx), glutathione reductase (GR), superoxide dismutase (SOD), catalase (CA), and malondialdehyde (MDA) levels were carried out on homogenised liver and brain. Treatment with PASE, CLQ and ATS combined with vitamin A, B, or E respectively, demonstrated significant increase in the serum levels of GPx and GR concentration. Treatment with PASE/ATS alone and in combination with vitamin A, B, C, and E significantly increased the liver GPX, SOD, and CA levels with significant decrease in liver MDA levels. Treatment with PASE/CLQ alone and in combination with vitamin A, B, C, and E significantly increased the brain GPX, GR and SOD levels with significant decrease in brain MDA levels. PASE showed enhanced antioxidant capacity in plasmodiasis solely or combined with vitamins A, B and E. Furthermore the co-administration of generic agent like artesunate with vitamins A, B, and E enhanced the antimalarial activity and treatment outcome as shown by the antioxidant effects. However, co-administration with vitamin C may be counter-productive.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.008
       
  • Backing of 2-(Diethylamino)-N-(2, 6-dimethylphenyl) – acetamide with
           Molecular, Electronic and Docking Studies

    • Authors: J. Deva Anban; Sayantan Pradhan; C. James
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): J. Deva Anban, Sayantan Pradhan, C. James
      In this study, the anaesthetic compound 2-(diethylamino)-N-(2, 6-dimethylphenyl)-acetamide (DEAL) was optimized with the B3LYP- 6-311+ G (d, p) density functional theory method. Hyper conjugative interactions revealed the bioactivity of the molecule by natural bond orbital analysis. The current–potential curves were noted at well-defined scan rates by cyclic voltammetry. The solvation free energy was calculated by applying the solvation model on density. Molecular docking simulations were carried out to understand the pharmacokinetic behaviour of the drug. Besides, total energy levels of HOMO-LUMO orbitals, Mulliken atomic charges, natural population analysis and polarizability properties of the molecule were calculated. We found that the secondary amide increases the stability of this molecule. The π→π∗ interactions increase the biological activity of the compound, leading to a very high stabilization.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.012
       
  • Hepatotoxicity and Genotoxicity of Gasoline Fumes in Albino Rats

    • Authors: Folarin O. Owagboriaye; Gabriel A. Dedeke; Joseph S. Ashidi; A.A. Aladesida; Wasiu E. Olooto
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Folarin O. Owagboriaye, Gabriel A. Dedeke, Joseph S. Ashidi, A.A. Aladesida, Wasiu E. Olooto
      Toxic effects of gasoline fumes have been reported, but evidence of its hepatotoxicity and genotoxicity are rare. Therefore, this study assesses hepatotoxicity and genotoxicity of gasoline fumes on forty Albino rats randomly assigned to five experimental treatments (T) with eight rats per treatment (T1, T2, T3, T4 and T5). T1(Control) was housed in a section of experimental animal house free from gasoline fumes while T2, T3, T4 and T5 were exposed to gasoline fumes in exposure chambers for one, three, five and nine hours daily respectively for twelve weeks. Serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP) and histopathological examination of the liver tissues were used as diagnostic markers to assess liver dysfunction. Genotoxicity test was conducted on the lung tissues using randomly amplified polymorphic DNA fingerprinting polymerase chain reaction (RAPD PCR) technique. Significant increase (p<0.05) in the level of ALT, AST and ALP for T2, T3, T4 and T5 compared to T1 were recorded. Photomicrograph examination of the liver sections of T1 showed hepatic tissue with normal liver cell architecture while that of T2, T3, T4 and T5 revealed degenerative changes in the ultrastructural integrity of the hepatic cells. Genotoxicity test revealed DNA bands at a reducing intensity from T1 to T5. Dendrogram showed DNA damage in the lungs of T3, T4 and T5 were closely similar and the genotoxic impact was more in T3. Frequent exposure to gasoline fumes was observed to induce hepatoxicity and genotoxicity, hence impairing the normal liver function and gene structure.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.007
       
  • Taurine Dietary Supplementation Attenuates Brain, Thyroid, Testicular
           Disturbances and Oxidative Stress in Streptozotocin-Induced Diabetes
           Mellitus in Male Rats

    • Authors: N.A. Mohamed; H.S. Abdel Gawad
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): N.A. Mohamed, H.S. Abdel Gawad
      The metabolic dysregulation associated with DM causes secondary pathophysiological changes in multiple organ systems. This work aimed to study the effect of taurine supplementation on brain, thyroid, testicular disturbances and oxidative stress in diabetic rats. Male Wistar rats were randomly divided into four groups (Group 1, control; group 2, diabetic; group 3, diabetic+taurine; group 4, taurine). The results illustrated that the dietary taurine intake was effective in lowering the elevated plasma levels of AChE, GnRH, TSH, FSH and LH in diabetic rats compared to untreated ones (P<0.05), whereas TRH, T3, T4 and testosterone, were significantly increased. Taurine improved the sperm characteristics in diabetic rats as indicated by sperm counts and motility. The data revealed that taurine intake was able to reverse the oxidative effect of diabetes on the antioxidant status of brain, thyroid and testis in diabetic rats. The taurine treated group also showed a significant improvement in the degenerative changes of the seminiferous tubules and spermatogenesis. In summary, it was suggested that taurine may have a regulatory effect on diabetes-induced changes in the gonadal-hormone levels by inhibiting hypothalamic–pituitary–gonadal axis and thyroid dysfunctions in the diabetic male rats.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.006
       
  • Internal Transcribed Sequence (ITS) ofHalocafeteria seosinensis
           (Bicosoecids)

    • Authors: Rathinam Raja; Shanmugam Hemaiswarya; Venkatesan ganesan; Isabel S Carvalho
      Abstract: Publication date: Available online 24 April 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Rathinam Raja, Shanmugam Hemaiswarya, Venkatesan ganesan, Isabel S Carvalho
      The aim of the current study was to characterize and identify the smaller subunit (18S) and Internal Transcribed Spacer (ITS) regions, ITS1 and ITS2 (ITS1-5.8S-ITS2) of Halocafeteria seosinensis (Bicosoecida). Halocafeteria was isolated from the salterns of Morocco and maintained using standard techniques. The ITS1 and ITS2 are non-conserved regions which were amplified using universal primers, ITS1 and ITS4. The purified PCR products were directly sequenced by Sanger dideoxy sequencing technology and submitted to GenBank. For the construction of cladogram, closely related 18S rDNA sequences obtained from GenBank were multiple aligned using MEGA 6 software and the cladogram constructed by maximum likelihood method with 10000 bootstrapping (BP) repetitions. The phylogenetic relationship among the other related stramenopiles were also studied. The molecular characterization by PCR of 18S genes was useful in confirming the taxonomic identity of a biflagellated H. seosinensis gen. et sp. nov. The ITS1-5.8S-ITS2 region of Halocafeteria is the one to be characterized for the very first time in the whole family of Bicosoecida. Due to discrepancy in placing Halocafeteria in Bicosoecida family, there is need in the characterization of ITS region sequences of stramenopiles and to use multigenes (such as 18S and ITS regions) for reconstructing the evolution tree.

      PubDate: 2017-04-26T15:19:11Z
      DOI: 10.1016/j.bjbas.2017.04.009
       
  • Supplementary studies of Pleurogenoides medians (Digenea:
           Lecithodendriidae) infecting the Marsh frog Rana Ridibunda (Amphibia:
           Ranidae) in Egypt

    • Authors: Rewaida Abdel-Gaber; Sherein Maher; Reem Kamel; Nashwa El Deeb
      Abstract: Publication date: Available online 9 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Rewaida Abdel-Gaber, Sherein Maher, Reem Kamel, Nashwa El Deeb
      Pleurogenoides medians, a digenean lecithodendriid trematode, parasitize numerous aquatic vertebrate species including frogs, freshwater fish, urodeles and anurans. In the present study, a total of 190 out of 300 (63.33%) marsh frogs Rana Ridibunda were found to be infected with this digenean parasite. The highest percentage of infection was recorded in winter reaching 93.33%, and the lowest value was recorded to be 6.66% during summer. Prevalence and intensity of infection were positively correlated with the host size. Host sex showed no effect in this respect. Morphological studies based on light and scanning electron microscopy revealed that the adult worms characterized by small body size measured 1.980-2.430 (2.205±0.1) mm long and 0.870-1.20 (9.87±0.01) mm wide with spines of similar size distributed all over the body surface; oral sucker is sub-terminal and measured 0.180-0.230 (0.203±0.01) mm long and 0.120-0.180 (0.150±0.01) mm wide; ventral sucker is smaller than the oral sucker, post-ovarian located at 1/3 level from the anterior end and measured 0.080-0.102 (0.090±0.001) mm long and 0.100-0140 (0.120±0.001) mm wide; two symmetrical testes were located near the cecal termination on both sides of the ventral sucker, measured 0.153-0.193 (0.176±0.01) mm long and 0.160-0.192 (0.175±0.01) mm wide; pre-acetabular ovary was present and measured 0.130-0.150 (0.140±0.01) mm long and 0.100-0.130 (0.120±0.01) mm wide; vitellaria are extra-caecal and extended from the level of the pharynx to a level slightly beyond the ovary. By comparing the recovered parasite with different species of the same genus from different hosts having different localities, it was found that the present species morphometrically more or less different from the comparable species and the only similar species was P. medians described previously from the common toad Bufo bufo by having all similar characteristic features. In addition, the present study was considered as the first report for the occurrence of this lecithodendriid species infecting the marsh frog in Egypt.

      PubDate: 2017-03-15T14:48:32Z
      DOI: 10.1016/j.bjbas.2017.03.001
       
  • Reproductive responses of primiparous and multiparous Holstein cows
           submitted to presynch-ovsynch protocol

    • Authors: R.L. Abdel Aziz; A. Abdel-Wahab
      Abstract: Publication date: Available online 2 March 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): R.L. Abdel Aziz, A. Abdel-Wahab
      The specific objective of this study was to determine the reproductive responses of primiparous (n=446) and multiparous (n=726) Holstein cows submitted to 12-day presynch-ovsynch protocol under the Egyptian circumstances. Distribution of inter-estrus intervals (IEI) and conception rate to first insemination (FICR) was compared between primiparous and multiparous cows. Furthermore, Seasonal variations of heat detection rate (HDR), conception rate (CR) and pregnancy rate (PR) were investigated. Short IEI tended to be higher in multiparous cows (23.8 vs 20.44%, P=0.09) compared to primiparous cows. In addition, the incidence of prolonged IEI was decreased from 21.53% in multiparous cows to 16.77% in primiparous cows. On contrary, normal length IEI was 62.78% in primiparous cows, higher than that observed in multiparous cows (54.67%). Moreover, primiparous cows inseminated earlier postpartum (<50 days) achieved higher FICR (31.79%) than multiparous cows (24.46%). Controversially, a tendency toward higher FICR was observed for multiparous cows inseminated after 70 days postpartum (31.89% vs. 23.17%, respectively; P=0.15). No clear variations in HDR were observed among different seasons, whereas greater CR and PR (P<0.05) were achieved by cows inseminated during Winter (35.37 and 24.90) and Spring (36.36 and 24.68), compared to those inseminated during Summer (10 and 6.6) and Autumn (21.59 and 15.63). Conceivably, our results demonstrate that primiparous Holstein cows responded better than multiparous cows to the 12-day presynch-ovsynch protocol as evidenced by higher incidence of normal length IEI, lower incidence of short and prolonged IEI and higher FICR. Furthermore, Summer season had significant negative and delayed effects on fertility of Holstein cows submitted to the 12-day Presynch-ovsynch protocol.

      PubDate: 2017-03-07T14:42:59Z
      DOI: 10.1016/j.bjbas.2017.02.005
       
  • Parameter identification for nonlinear damping coefficient from
           large-amplitude ship roll motion using wavelets

    • Authors: D. Sathyaseelan; G. Hariharan; K. Kannan
      Abstract: Publication date: Available online 27 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): D. Sathyaseelan, G. Hariharan, K. Kannan
      In this paper, we have introduced an efficient Legendre wavelet spectral method (LWSM) to ship roll motion model for investigating the nonlinear damping coefficients. The accuracy of the proposed method is assessed by rolling with an initial amplitude using nonlinear type of equations. To the best of our knowledge until now there is no rigorous wavelet solution has been reported for the above model. Convergence analysis of the proposed method is discussed. The operational matrix of derivative is utilized to convert a ship roll motion equation into a set of algebraic equations. Accurate coefficients can be easily obtained for large rolling angles up to the amplitude at the maximum value of the restoring moment using wavelets. Some numerical examples are given to show the validity and applicability of the proposed wavelet method. Moreover the use of Legendre wavelets is found to be simple,flexible, accurate, efficient and small computation cost.

      PubDate: 2017-03-01T14:39:16Z
      DOI: 10.1016/j.bjbas.2017.02.003
       
  • Meta-analysis of Staphylococcal Diarrhea in Some Developing African
           Countries

    • Authors: George P. Einstein; Orien L. Tulp; Temitope C. Oyesile; Olayide F. Obidi
      Abstract: Publication date: Available online 22 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): George P. Einstein, Orien L. Tulp, Temitope C. Oyesile, Olayide F. Obidi
      Staphylococcal diarrhea is a common gastro-intestinal illness caused by poor water supply and unhygienic food preparation. Although, about 70% of diarrheal cases per year have been attributed to the consumption of contaminated foods, in Africa, few studies have reported the incidence of Staphylococcus-related diarrhea and the implicated virulence factors. We investigated the implications of common factors such as age of children, age of mothers, maternal level of education, gender of children, overall bacteria isolated, sanitary condition status and feeding type of mothers on the burden of staphylococcal diarrhea. A literature search was performed using Pubmed, Googlescholar, American society for microbiology (ASM) journals and other sources. The quality of studies was assessed. Adjusted odds ratios with 95% confidence intervals (CI) for the occurrence of staphylococcus aureus amongst other causes were extracted. For each study, a multivariate logistic regression analysis of the adjusted odds ratio was performed to identify the risk factors on the burden of staphylococcal diarrhea. Six case-control studies were included in the meta–analysis. Quality of individual studies rages from 0.57–0.84 (median, 0.69). Meta-analysis gave pooled odds ratios 3.27 (95% CI; 2.88–4.17). The results identified inadequate sanitary conditions and type of feeding as major risk factors.

      PubDate: 2017-03-01T14:39:16Z
      DOI: 10.1016/j.bjbas.2017.02.004
       
  • Flow Improvement at Pump Intake by the Use of Baffle Posts

    • Authors: Mohamed Mohamed Abdellatif Mohamed
      Abstract: Publication date: Available online 16 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Mohamed Mohamed Abdellatif Mohamed
      Poor design of intake structures surrounding the hydraulic pump causes undesirable flow problems. These flow problems are in the form of severe vortices, and/or uneven flow distribution at pump intake. There are several methods in the literature to suppress such vortices but such methods might have an adverse impact on the operation and maintenance of the intake structure. In this paper, a new approach was investigated to reduce the vortex activity without any adverse impacts on the operation process. This approach depends on installing baffle posts on the top of the upstream side and the offshore long side of the sedimentation basin of the intake structure. An existing physical model of undistorted scale 1:38 was utilized to reduce the vortex activity using baffle posts. The model shows that baffle posts are effective in eliminating the vortex activity and hence improving the approach flow at the intake structure.

      PubDate: 2017-02-22T02:34:21Z
      DOI: 10.1016/j.bjbas.2017.02.002
       
  • Underutilized Luffa cylindrica sponge: A local bio-adsorbent for the
           removal of Pb (II) pollutant from water system

    • Authors: Adewale Adewuyi; Fabiano Vargas Pereira
      Abstract: Publication date: Available online 16 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Adewale Adewuyi, Fabiano Vargas Pereira
      Biosorption of Pb2+ ions from aqueous solution onto Luffa cylindrica sponge as adsorbent (LCSA) was investigated in batch adsorption system. LCSA was characterized by X-ray Diffraction analysis technique (XRD), Scanning Electron Microscopy (SEM) coupled with energy dispersive spectroscopy (EDS), Fourier Transform Infrared spectrometer (FTIR), particle size dispersion, zeta potential, thermogravimetric analysis (TGA), and Brunauer-Emmett-Teller (BET) surface area analyzer. The sorption of Pb2+ ions by LCSA was subjected to equilibrium, thermodynamics and kinetic studies and was carried out by considering the effects of pH, initial metal ions concentration, contact time and temperature. BET surface area of LCSA was 6.00 m2/g with mean distribution size of 0.02 micron while the zeta potential was found to increase as the value of pH increased from 4-14. The findings revealed the maximum equilibrium adsorption capacity to be 75.853 mg/g. The process is chemisorptive and controlled by intra-particle diffusion. The values of thermodynamic parameters such as ΔGo, ΔHo and ΔSo showed a stable adsorbent-adsorbate (LCSA-Pb) configuration which is exothermic. The adsorption capacity of LCSA compared better than some natural bio-sorbent found in literature.

      PubDate: 2017-02-22T02:34:21Z
      DOI: 10.1016/j.bjbas.2017.02.001
       
  • Staphylococcal Bacteraemia among Human Immunodeficiency Virus Positive
           Patients at a Screening Center in Lagos, Nigeria

    • Authors: Solayide A. Adesida; Olusegun A. Abioye; Babajide S. Bamiro; Kehinde O. Amisu; Sikiru O. Badaru; Akitoye O. Coker
      Abstract: Publication date: Available online 3 February 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Solayide A. Adesida, Olusegun A. Abioye, Babajide S Bamiro, Kehinde O Amisu, Sikiru O Badaru, Akitoye O Coker
      Bacteraemia due to Staphylococcus aureus in Human immunodeficiency virus (HIV) - positive patients is associated with increased mortality rate. The present study aimed at determining the species distribution and occurrence of staphylococcal bacteremia in HIV – positive patients in Lagos, Nigeria. Staphylococcal blood stream infection in febrile HIV patients was investigated by culture technique. The antibiotic resistance pattern was investigated using the disk diffusion and methicillin resistance was confirmed by the salt agar methods. The genetic relatedness of S. aureus was determined using Pulsed Field Gel Electrophoresis (PFGE). Eighty-six patients comprising 47 (55%) female and 39 (45%) male, median aged 34 years took part in the study. Staphylococci were identified in 16 (18.6%) patients; 13 (15.1%) and 3 (3.5%) with single and dual Staphylococcus species respectively. The isolates consisted of S. aureus (7 patients), followed by S. haemolyticus (4 patients). Of the thirteen (13) antibiotics tested, isolates were resistant to ampicillin (AMP; 89.5%), tetracycline (TET; 68.4%), cloxacillin (CXC; 89.5%), oxacillin (OXA; 68.4%); chloramphenicol (CHL; 57.9%) and trimethoprim-sulphamethoxazole (SXT; 63.1%). The overall percentage of all the isolates resistant to gentamicin, erythromycin and amoxicillin-clavulanic acid was less than 50%. The isolates were ciprofloxacin and vancomycin susceptible. None of the isolates was positive for methicillin resistance except strain of S. haemolyticus. A significant genetic diversity was observed among S. aureus isolates with a predominant pulsotype A. The two isolates with pulsotype A also had identical resistotype (AMP, ERY, TET, CXC, SXT). Other PFGE patterns were represented by single isolates except pulsotype C which had a subtype. In these patients, the most frequent Staphylococcus species isolated was S. aureus and the results revealed that clonal dissemination of a virulent pulsotype of S. aureus among this population is plausible and should be a cause for concern.

      PubDate: 2017-02-09T02:25:16Z
      DOI: 10.1016/j.bjbas.2016.08.006
       
  • A new fuzzy regression model based on interval-valued fuzzy neural network
           and its applications to management

    • Authors: Somaye yeylaghi; Mahmood Otadi; Niloofar Imankhan
      Abstract: Publication date: Available online 28 January 2017
      Source:Beni-Suef University Journal of Basic and Applied Sciences
      Author(s): Somaye yeylaghi, Mahmood Otadi, Niloofar Imankhan
      In this paper, a novel hybrid method based on interval-valued fuzzy neural network for approximate of interval-valued fuzzy regression models, is presented. The work of this paper is an expansion of the research of real fuzzy regression models. In this paper interval-valued fuzzy neural network (IVFNN) can be trained with crisp and interval-valued fuzzy data. Here a neural network is considered as a part of a large field called neural computing or soft computing. Moreover, in order to find the approximate parameters, a simple algorithm from the cost function of the fuzzy neural network is proposed. Finally, we illustrate our approach by some numerical examples and compare this method with existing methods.

      PubDate: 2017-02-03T02:21:29Z
      DOI: 10.1016/j.bjbas.2017.01.004
       
 
 
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