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CHEMISTRY (537 journals)                  1 2 3 4 5 6 | Last

2D Materials     Hybrid Journal   (Followers: 3)
Accreditation and Quality Assurance: Journal for Quality, Comparability and Reliability in Chemical Measurement     Hybrid Journal   (Followers: 31)
ACS Catalysis     Full-text available via subscription   (Followers: 24)
ACS Chemical Neuroscience     Full-text available via subscription   (Followers: 13)
ACS Combinatorial Science     Full-text available via subscription   (Followers: 8)
ACS Macro Letters     Full-text available via subscription   (Followers: 17)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 25)
ACS Nano     Full-text available via subscription   (Followers: 270)
ACS Photonics     Full-text available via subscription   (Followers: 2)
ACS Synthetic Biology     Full-text available via subscription   (Followers: 8)
Acta Chemica Iasi     Open Access  
Acta Chimica Sinica     Full-text available via subscription  
Acta Chimica Slovaca     Open Access   (Followers: 5)
Acta Chromatographica     Full-text available via subscription   (Followers: 10)
Acta Facultatis Medicae Naissensis     Open Access   (Followers: 1)
Acta Metallurgica Sinica (English Letters)     Hybrid Journal   (Followers: 4)
adhäsion KLEBEN & DICHTEN     Hybrid Journal   (Followers: 3)
Adhesion Adhesives & Sealants     Hybrid Journal   (Followers: 4)
Adsorption Science & Technology     Full-text available via subscription   (Followers: 8)
Advanced Functional Materials     Hybrid Journal   (Followers: 34)
Advances in Chemical Engineering and Science     Open Access   (Followers: 21)
Advances in Chemical Science     Open Access   (Followers: 8)
Advances in Colloid and Interface Science     Full-text available via subscription   (Followers: 13)
Advances in Drug Research     Full-text available via subscription   (Followers: 17)
Advances in Fluorine Science     Full-text available via subscription   (Followers: 7)
Advances in Fuel Cells     Full-text available via subscription   (Followers: 12)
Advances in Heterocyclic Chemistry     Full-text available via subscription   (Followers: 8)
Advances in Materials Physics and Chemistry     Open Access   (Followers: 13)
Advances in Nanoparticles     Open Access   (Followers: 11)
Advances in Organometallic Chemistry     Full-text available via subscription   (Followers: 8)
Advances in Polymer Science     Hybrid Journal   (Followers: 38)
Advances in Protein Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 10)
Advances in Quantum Chemistry     Full-text available via subscription   (Followers: 4)
African Journal of Chemical Education     Open Access   (Followers: 1)
African Journal of Pure and Applied Chemistry     Open Access   (Followers: 4)
Afrique Science : Revue Internationale des Sciences et Technologie     Open Access  
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
Alchemy     Open Access   (Followers: 3)
Alkaloids: Chemical and Biological Perspectives     Full-text available via subscription   (Followers: 4)
AMB Express     Open Access   (Followers: 1)
American Journal of Applied Sciences     Open Access   (Followers: 28)
American Journal of Biochemistry and Biotechnology     Open Access   (Followers: 165)
American Journal of Biochemistry and Molecular Biology     Open Access   (Followers: 11)
American Journal of Chemistry     Open Access   (Followers: 17)
American Journal of Plant Physiology     Open Access   (Followers: 9)
American Mineralogist     Full-text available via subscription   (Followers: 2)
Analyst     Full-text available via subscription   (Followers: 35)
Angewandte Chemie     Hybrid Journal   (Followers: 16)
Angewandte Chemie International Edition     Hybrid Journal   (Followers: 213)
Annales UMCS, Chemia     Open Access   (Followers: 2)
Annual Reports in Computational Chemistry     Full-text available via subscription   (Followers: 1)
Annual Reports Section A (Inorganic Chemistry)     Full-text available via subscription   (Followers: 2)
Annual Reports Section B (Organic Chemistry)     Full-text available via subscription   (Followers: 4)
Annual Review of Chemical and Biomolecular Engineering     Full-text available via subscription   (Followers: 10)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 12)
Anti-Infective Agents     Hybrid Journal   (Followers: 1)
Applied Organometallic Chemistry     Hybrid Journal   (Followers: 4)
Applied Spectroscopy     Full-text available via subscription   (Followers: 12)
Applied Surface Science     Hybrid Journal   (Followers: 14)
Arabian Journal of Chemistry     Full-text available via subscription   (Followers: 6)
ARKIVOC     Open Access   (Followers: 1)
Asian Journal of Biochemistry     Open Access   (Followers: 1)
Australian Journal of Chemistry     Hybrid Journal   (Followers: 4)
Autophagy     Full-text available via subscription   (Followers: 1)
Avances en Quimica     Open Access   (Followers: 1)
Biochemical Pharmacology     Hybrid Journal   (Followers: 6)
Biochemistry     Full-text available via subscription   (Followers: 204)
Biochemistry Insights     Open Access   (Followers: 4)
Biochemistry Research International     Open Access   (Followers: 4)
BioChip Journal     Hybrid Journal   (Followers: 1)
Bioinorganic Chemistry and Applications     Open Access   (Followers: 4)
Biointerface Research in Applied Chemistry     Open Access   (Followers: 1)
Biointerphases     Open Access  
Biomacromolecules     Full-text available via subscription   (Followers: 17)
Biomass Conversion and Biorefinery     Partially Free   (Followers: 5)
Biomedical Chromatography     Hybrid Journal   (Followers: 7)
Biomolecular NMR Assignments     Hybrid Journal   (Followers: 2)
BioNanoScience     Partially Free   (Followers: 4)
Bioorganic & Medicinal Chemistry     Hybrid Journal   (Followers: 30)
Bioorganic & Medicinal Chemistry Letters     Hybrid Journal   (Followers: 24)
Bioorganic Chemistry     Hybrid Journal   (Followers: 5)
Biopolymers     Hybrid Journal   (Followers: 13)
Biosensors     Open Access   (Followers: 3)
Biotechnic and Histochemistry     Hybrid Journal   (Followers: 1)
Boletin de la Sociedad Chilena de Quimica     Open Access  
Bulletin of the Chemical Society of Ethiopia     Open Access   (Followers: 1)
Bulletin of the Chemical Society of Japan     Full-text available via subscription   (Followers: 12)
Canadian Association of Radiologists Journal     Full-text available via subscription   (Followers: 3)
Canadian Journal of Chemistry     Full-text available via subscription   (Followers: 6)
Canadian Mineralogist     Full-text available via subscription   (Followers: 1)
Carbohydrate Research     Hybrid Journal   (Followers: 10)
Carbon     Hybrid Journal   (Followers: 37)
Catalysis for Sustainable Energy     Open Access   (Followers: 2)
Catalysis Reviews: Science and Engineering     Hybrid Journal   (Followers: 4)
Catalysis Science and Technology     Free   (Followers: 4)
Catalysis Surveys from Asia     Hybrid Journal   (Followers: 4)
Catalysts     Open Access   (Followers: 6)
Cellulose     Hybrid Journal   (Followers: 4)
Central European Journal of Chemistry     Hybrid Journal   (Followers: 5)

        1 2 3 4 5 6 | Last

Journal Cover Chemistry & Biodiversity
   Journal TOC RSS feeds Export to Zotero [7 followers]  Follow    
   Hybrid Journal Hybrid journal (It can contain Open Access articles)
     ISSN (Print) 1612-1872 - ISSN (Online) 1612-1880
     Published by John Wiley and Sons Homepage  [1604 journals]   [SJR: 0.541]   [H-I: 35]
  • Contents: C&B 9/2014
    • PubDate: 2014-09-19T04:48:31.290126-05:
      DOI: 10.1002/cbdv.201490009
  • Chemical Constituents of Plants from the Genus Paris
    • Authors: Jin‐Chao Wei; Wen‐Yuan Gao, Xiao‐Dan Yan, Ying Wang, Song‐Song Jing, Pei‐Gen Xiao
      First page: 1277
      PubDate: 2014-09-19T04:48:33.021972-05:
      DOI: 10.1002/cbdv.201300083
  • In Vitro and In Vivo Evaluation of
           a Positron Emission Tomography (PET) Radioligand for Dopamine D4
           Receptors, in Rodents
    • Authors: Marcello Leopoldo; Svetlana V. Selivanova, Adrienne Müller, Enza Lacivita, John A. Schetz, Simon M. Ametamey
      First page: 1298
      Abstract: The D4 dopamine receptor belongs to the D2‐like family of dopamine receptors, and its exact regional distribution in the central nervous system is still a matter of considerable debate. The availability of a selective radioligand for the D4 receptor with suitable properties for positron emission tomography (PET) would help resolve issues of D4 receptor localization in the brain, and the presumed diurnal change of expressed protein in the eye and pineal gland. We report here on in vitro and in vivo characteristics of the high‐affinity D4 receptor‐selective ligand N‐{2‐[4‐(3‐cyanopyridin‐2‐yl)piperazin‐1‐yl]ethyl}‐3‐[11C]methoxybenzamide ([11C]2) in rat. The results provide new insights on the in vitro properties that a brain PET dopamine D4 radioligand should possess in order to have improved in vivo utility in rodents.
      PubDate: 2014-09-19T04:48:33.97149-05:0
      DOI: 10.1002/cbdv.201400178
  • Small Molecules as Exemplars of Emergent Properties and Diversification
           into the ‘Adjacent Possible’
    • Authors: Bernard Testa; Giulio Vistoli, Alessandro Pedretti
      First page: 1309
      PubDate: 2014-09-19T04:48:31.639613-05:
      DOI: 10.1002/cbdv.201400177
  • (Un)Targeted Metabolomics in Asteraceae: Probing the Applicability of
           Essential‐Oil Profiles of Senecio L. (Senecioneae) Taxa in
    • Authors: Niko S. Radulović; Marko Z. Mladenović, Polina D. Blagojević
      First page: 1330
      Abstract: The possible applicability of (un)targeted metabolomics (volatile metabolites) for revealing taxonomic/evolutionary relationships among Senecio L. species (Asteraceae; tribe Senecioneae) was explored. Essential‐oil compositional data of selected Senecio/Senecioneae/Asteraceae taxa (93 samples in total) were mutually compared by means of multivariate statistical analysis (MVA), i.e., agglomerative hierarchical clustering and principal component analysis. The MVA input data set included the very first compositional data on the essential oil extracted from the aerial parts of S. viscosus L. as well as on four different Serbian populations of S. vernalis Waldst. & Kit. (oils from aerial parts and roots; eight samples in total). This metabolomic screening of Senecio/Senecioneae/Asteraceae species (herein presented results and data from the literature) pointed to short‐chain alk‐1‐enes (e.g., oct‐1‐ene, non‐1‐ene, and undec‐1‐ene), with up to now restricted general occurrence in Plantae, as characteristic chemotaxonomic markers/targets for future metabolomic studies of Senecio/Senecioneae taxa. The MVA additionally showed that the evolution of the terpene metabolism (volatile mono‐ and sesquiterpenoids) within the Asteraceae tribe Senecioneae was not genera specific. However, the MVA did confirm plant‐organ specific production/accumulation of volatiles within S. vernalis and suggested the existence of at least two volatile chemotypes for this species.
      PubDate: 2014-09-19T04:48:30.88987-05:0
      DOI: 10.1002/cbdv.201400036
  • Triterpenoids as Novel Natural Inhibitors of Human Cathepsin L
    • Authors: Suelem D. Ramalho; Lorena R. F. De Sousa, Liliane Nebo, Stella H. Maganhi, Ignez Caracelli, Julio Zukerman‐Schpector, Maria Inês S. Lima, Marcio F. M. Alves, M. Fátima das G. F. Da Silva, João B. Fernandes, Paulo C. Vieira
      First page: 1354
      Abstract: Cathepsins L (catL) and B play an important role in tumor progression and have been considered promising therapeutic targets in the development of novel anticancer agents. Using a bioactivity‐guided fractionation, a series of triterpenoids was identified as a new class of competitive inhibitors towards cathepsin L with affinity values in micromolar range. Among the 14 compounds evaluated, the most promising were 3‐epiursolic acid (3), 3‐(hydroxyimino)oleanolic acid (9), and 3‐(hydroxyimino)masticadienoic acid (13) with IC50 values of 6.5, 2.4, and 2.6 μM on catL, respectively. Most of the evaluated triterpenoids do not inhibit cathepsin B. Thus, the evaluated compounds exhibit a great potential to help in the design of new inhibitors with enhanced potency and affinity towards catL. Docking studies were performed in order to gain insight on the binding mode and SAR of these compounds.
      PubDate: 2014-09-19T04:48:34.49245-05:0
      DOI: 10.1002/cbdv.201400065
  • ‘Yeast Mail’: A Novel Saccharomyces Application (NSA) to
           Encrypt Messages
    • Authors: Helmut Rosemeyer; Achim Paululat, Jürgen J. Heinisch
      First page: 1364
      Abstract: The universal genetic code is used by all life forms to encode biological information. It can also be used to encrypt semantic messages and convey them within organisms without anyone but the sender and recipient knowing, i.e., as a means of steganography. Several theoretical, but comparatively few experimental, approaches have been dedicated to this subject, so far. Here, we describe an experimental system to stably integrate encrypted messages within the yeast genome using a polymerase chain reaction (PCR)‐based, one‐step homologous recombination system. Thus, DNA sequences encoding alphabetical and/or numerical information will be inherited by yeast propagation and can be sent in the form of dried yeast. Moreover, due to the availability of triple shuttle vectors, Saccharomyces cerevisiae can also be used as an intermediate construction device for transfer of information to either Drosophila or mammalian cells as steganographic containers. Besides its classical use in alcoholic fermentation and its modern use for heterologous gene expression, we here show that baker's yeast can thus be employed in a novel Saccharomyces application (NSA) as a simple steganographic container to hide and convey messages.
      PubDate: 2014-09-19T04:48:32.32272-05:0
      DOI: 10.1002/cbdv.201400160
  • New Thymol Derivatives and Cytotoxic Constituents from the Root of
           Eupatorium cannabinum ssp. asiaticum
    • Authors: Li‐Chai Chen; Tzong‐Huei Lee, Ping‐Jyun Sung, Chih‐Wen Shu, Yun‐Ping Lim, Ming‐Jen Cheng, Wen‐Lung Kuo, Jih‐Jung Chen
      First page: 1374
      Abstract: Two new thymol (=5‐methyl‐2‐(1‐methylethyl)phenol) derivatives, 8,10‐didehydro‐9‐(3‐methylbutanoyl)thymol 3‐O‐tiglate (1) and 9‐O‐angeloyl‐8‐methoxythymol 3‐O‐isobutyrate (2), were isolated from the root of Eupatorium cannabinum ssp. asiaticum, together with six known compounds, 3–8. The structures of 1 and 2 were determined through extensive 1D/2D‐NMR and MS analyses. Among the isolates, 9‐acetoxy‐8,10‐epoxythymol 3‐O‐tiglate (3) was the most cytotoxic, with IC50 values of 0.02±0.01, 1.02±0.07, and 1.36±0.12 μg/ml, respectively, against DLD‐1, CCRF‐CEM, and HL‐60 cell lines. In addition, 10‐acetoxy‐9‐O‐angeloyl‐8‐hydroxythymol (4) and eupatobenzofuran (6) exhibited cytotoxicities, with IC50 values of 1.14±0.16 and 2.63±0.22, and 7.63±0.94 and 2.31±0.14 μg/ml, respectively, against DLD‐1 and CCRF‐CEM cell lines.
      PubDate: 2014-09-19T04:48:33.443396-05:
      DOI: 10.1002/cbdv.201300392
  • Synthesis, Characterization, and Antibacterial Activity of Structurally
           Complex 2‐Acylated 2,3,1‐Benzodiazaborines and Related
    • Authors: Divya Kanichar; Lance Roppiyakuda, Ewa Kosmowska, Michelle A. Faust, Kim P. Tran, Felicia Chow, Elena Buglo, Michael P. Groziak, Evan A. Sarina, Marilyn M. Olmstead, Isba Silva, H. Howard Xu
      First page: 1381
      Abstract: A set of 2‐acylated 2,3,1‐benzodiazaborines and some related boron heterocycles were synthesized, characterized, and tested for antibacterial activity against Escherichia coli and Mycobacterium smegmatis. By high‐field solution NMR, the heretofore unknown class of 2‐acyl‐1‐hydroxy‐2,3,1‐diazaborines has been found to be able to exist in several interconvertable structural forms along a continuum comprised of an open hydrazone a, a monomeric B‐hydroxy diazaborine b, and an anhydro dimer c. X‐Ray crystallography of one of the anhydro dimers, 17c, revealed it to have an unprecedented structure featuring a double intramolecular O→B chelation. The crystal structure of another compound, 37, showed it to be based on a new pentacyclic B heterocycle framework. Nine compounds were found to possess activities against E. coli, and two others were active against M. smegmatis. The finding that these two contain isoniazid covalently embedded in their structures suggests that they might possibly be acting as prodrugs of this well‐known antituberculosis agent in vivo.
      PubDate: 2014-09-19T04:48:32.549358-05:
      DOI: 10.1002/cbdv.201400007
  • Fragrant Volatile Sesquiterpenoids Isolated from the Essential Oil of
           Laggera pterodonta by Using Olfactory‐Guided Fractionation
    • Authors: Jian‐Long Gu; Zhi‐Jian Li, Hong‐Xia Zhang, Zhi‐Zhi Du
      First page: 1398
      Abstract: Chemical composition of the essential oil from Laggera pterodonta (Compositae) was inverstigated. GC/MS Analyses led to the identification of 68 components, representing more than 96% of the total oil. By focusing on the woody note fraction of the essential oil, one new bisabolane‐type sesquiterpenoid, bisabola‐2,7(14),11‐trien‐10‐ol (1), together with ten known compounds, bisabolol oxide B (2), ylangenol (3), copaborneol (4), guai‐11‐en‐10‐ol (5), spathulenol (6), aromadendran‐10‐ol (7), caryophyllenol (8), 5α,7α‐eudesm‐11(13)‐en‐4α‐ol (9), γ‐costic acid (10), and eudesma‐4(15),11(13)‐diene‐12,5β‐olide (11), were isolated by using olfactory‐guided fractionation. The structures of the eleven compounds were determined by NMR and MS analyses. All the volatile compounds reported here were isolated for the first time from this plant. On the basis of preliminary odor assessment, the odor of the woody‐note fractions of the essential oil was assumed to be due to these isolated sesquiterpenoids.
      PubDate: 2014-09-19T04:48:30.543199-05:
      DOI: 10.1002/cbdv.201400051
  • Chemical Constituents from the Stems of Excoecaria acertiflia
    • Authors: Sheng‐Zhuo Huang; Huai‐Rong Luo, Qing‐Yun Ma, Hua Peng, Hao‐Fu Dai, Jun Zhou, You‐Xing Zhao
      First page: 1406
      Abstract: Six new compounds, including two diterpenoids excocarinols F and G (1 and 2, resp.), two carotane (daucane) sesquiterpenoids excoecafolinols A and B (3 and 4, resp.), one lignanoid compound, excoecanol A (5), and one simple phenol, excoecanol B (6), together with 17 known compounds, were isolated from the BuOH extract of Excoecaria acerifolia Didr. stems. Their structures were elucidated through the analysis of the spectroscopic data. The AChE‐inhibitory activities of 17 compounds were evaluated and revealed that four of them possessed moderate inhibitory activities against AChE.
      PubDate: 2014-09-19T04:48:35.031315-05:
      DOI: 10.1002/cbdv.201400087
  • Chloroform Extract of Underground Parts of Ferula heuffelii: Secondary
           Metabolites and Spasmolytic Activity
    • Authors: Ivan Pavlović; Aleksej Krunić, Dejan Nikolić, Mirjana Radenković, Suzana Branković, Marjan Niketić, Silvana Petrović
      First page: 1417
      Abstract: Plants from the genus Ferula L. (Apiaceae) were used for various purposes in traditional medicine of different nations throughout the history. Ferula heuffelii Griseb. ex Heuffel is a perennial species endemic for Balkan peninsula. Ten compounds which belong to classes of prenyl‐furocoumarin‐, prenyl‐dihydrofurochromone‐, prenyl‐benzoyl‐ and prenyl‐benzoylfuranone‐type sesquiterpenoids, as well as sesquiterpene coumarins and phenylpropanoids, were, for the first time, isolated from the CHCl3 extract of the underground parts of this plant and identified. Furthermore, extract and three isolated compounds, i.e., latifolone (1), dshamirone (4), and (2S*,3R*)‐2‐[(3E)‐4,8‐dimethylnona‐3,7‐dien‐1‐yl]‐2,3‐dihydro‐7‐hydroxy‐2,3‐dimethylfuro[3,2‐c]coumarin (6) were, for the first time, evaluated for their in vitro antispasmodic activities in three experimental models: spontaneous contraction, and ACh‐ and KCl‐induced contraction of an isolated rat ileum. The extract (0.1–1.3 mg/ml) and compound 6 (1–10 μg/ml) exhibited dose‐dependent effect in all three models. Compound 1 (1–6 μg/ml) affected spontaneous contractions and those induced by KCl, while compound 4 (8 μg/ml) displayed only moderate activity with ACh‐induced contractions. It can be concluded that tested compounds contribute to exhibited antispasmodic activity of crude extract. Additionally, extract (0.1–1.3 mg/ml) was tested for in vitro relaxant activity on an isolated rat trachea, and relaxed the KCl‐induced contractions in a dose‐dependent manner.
      PubDate: 2014-09-19T04:48:31.392288-05:
      DOI: 10.1002/cbdv.201400094
  • Further Amphoricarpolides from the Surface Extracts of Amphoricarpos
           Complex from Montenegro
    • Authors: Mirjana Cvetković; Iris Ðorđević, Milka Jadranin, Vlatka Vajs, Ivan Vučković, Nebojša Menković, Slobodan Milosavljević, Vele Tešević
      First page: 1428
      Abstract: Analysis of composition of sesquiterpene lactone fraction of leaf cuticular neutral lipids of Amphoricarpos complex from two different localities in north Montenegro, i.e., canyon of river Tara (A. autariatus ssp. autariatus) and mountain Zeletin (A. autariatus ssp. bertisceus) afforded sesquiterpene lactones with guaianolide skeletons (17 compounds), so called amphoricarpolides, typical for this genus. Nine of them, 9–17, were new compounds, and their structures were elucidated by detailed analyses of IR, NMR, and MS data.
      PubDate: 2014-09-19T04:48:32.047532-05:
      DOI: 10.1002/cbdv.201400101
  • Chemical and Genetic Studies on Hybrid of Ligularia subspicata and
           Ligularia cyathiceps Collected in Yunnan Province of China
    • Authors: Anna Shimizu; Shizuka Watanabe, Ryo Hanai, Yasuko Okamoto, Motoo Tori, Xun Gong, Chiaki Kuroda
      First page: 1438
      Abstract: Two morphologically ambiguous Ligularia samples (samples A and B), and samples with morphology of Ligularia subspicata (sample C), Ligularia lamarum (sample D), or Ligularia cyathiceps (sample E), were collected at Tianchi Pond, Shangrila County, Yunnan Province, China. Analysis of the nucleotide sequence of the internal transcribed spacers (ITSs) in the nuclear ribosomal RNA gene cluster indicated that not only sample B but also sample D was a hybrid of L. cyathiceps and L. lamarum/L. subspicata. Although the morphology of sample A suggested that it was also a hybrid, the ITS sequence of sample A was that of L. cyathiceps. Twenty compounds were isolated from the five samples, and the structures of two new compounds 7 and 14 were determined. Furanoeremophilanes typical of L. lamarum/L. subspicata were detected not only in samples C and D, but also in samples A and B. These results indicate that the ability to produce root chemicals can spread through introgression.
      PubDate: 2014-09-19T04:48:34.763012-05:
      DOI: 10.1002/cbdv.201400133
  • Chemical Constituents and Activities of the Essential Oil from Myristica
           fragrans against Cigarette Beetle Lasioderma serricorne
    • Authors: Shu‐Shan Du; Kai Yang, Cheng‐Fang Wang, Chun‐Xue You, Zhu‐Feng Geng, Shan‐Shan Guo, Zhi‐Wei Deng, Zhi‐Long Liu
      First page: 1449
      Abstract: Essential oil extracted from nutmeg seeds (Myristica fragrans Houtt.) by hydrodistillation was subjected to GC/MS and GC analysis. A total of 27 constituents were identified, of which eugenol (19.9%), methylisoeugenol (16.8%), methyleugenol (16.7%), sabinene (11.8%), and terpinen‐4‐ol (8.5%) were the major components. The essential oil was tested against Lasioderma serricorne for insecticidal and repellent activity, the LD50 value at the end of 24 h exposure period was 19.3 μg/adult. Six active compounds were isolated by bioassay‐guided fractionation. They were identified as eugenol (1), methyleugenol (2), methylisoeugenol (3), elemicin (4), myristicin (5), and safrole (6). Among these isolates, 4 showed the strongest contact toxicity against L. serricorne adults with an LD50 value of 9.8 μg/adult. Repellency of crude oil and active compounds were also determined. Compounds 1, 2, 4, and 5 were strongly repellent against the cigarette beetle and exhibited the same level of repellency compared with the positive control, DEET. The results indicate that the essential oil of M. fragrans and its active constituents have potential for development as natural insecticides and repellents to control L. serricorne.
      PubDate: 2014-09-19T04:48:33.652448-05:
      DOI: 10.1002/cbdv.201400137
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