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Journal Cover Progress in Heterocyclic Chemistry
  [SJR: 0.24]   [H-I: 18]   [0 followers]  Follow
    
   Full-text available via subscription Subscription journal
   ISSN (Print) 0959-6380
   Published by Elsevier Homepage  [3039 journals]
  • Chapter 5.2 Five-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Justin M. Lopchuk
      The reactions and syntheses of pyrroles, indoles, isatins, carbazoles, and related fused heterocyclic ring systems from the year 2015 are reviewed. Pyrroles and indoles are treated in separate sections with the ring-forming reactions discussed by intramolecular or intermolecular bond disconnection. Other sections include nucleophilic, electrophilic, or radical reactivity of the parent rings; C–H functionalization/organometallic reactions; reactions of side chains; and examples in total synthesis.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 5.1 Five-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Edward R. Biehl
      This chapter presents the synthesis of thiophenes, selenophenes and tellurophenes and their subsequent cyclization to corresponding bicyclo derivatives and/or substituted ring derivatives by appropriate substitution reaction. The application of these derivatives to material, photospectroscopic and medicinal sciences are briefly discussed.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 4 Four-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Josefa Anaya, Ramón M. Sánchez
      The review covers work published in the calendar year 2015. The synthesis and reactivity of four-membered heteroatom-containing cycles are reviewed. New developments in the chemistry of these strained heterocycles, especially β-lactams, are covered.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 3 Three-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Jeanese C. Badenock
      The syntheses and reactions of three-membered heterocycles, particularly epoxides, aziridines, and azirines, reported in the literature during 2015 are reviewed. Particular emphasis is placed on the use of these units as synthons in the construction of more elaborate heterocyclic compounds.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 1 Semi-Conjugated Heteroaromatic Rings
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Christopher A. Ramsden
      A systematic analysis of the connectivity of heteroatoms in heterocyclic mesomeric betaines (HMBs) reveals three main classes: conjugated HMBs, cross-conjugated HMBs, and the previously unrecognized semi-conjugated HMBs. The defining features of each class are discussed with particular emphasis on semi-conjugated systems.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 2 Recent Progress in the Use of Functionalized β-Lactams as
           Building Blocks in Heterocyclic Chemistry
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Nicola Piens, Norbert De Kimpe, Matthias D’hooghe
      β-Lactams represent versatile building blocks in heterocyclic chemistry. This chapter covers recent methodologies for the preparation of functionalized six-membered and three-membered azaheterocycles by ring transformation of azetidin-2-ones. Furthermore, emerging topics including the synthesis of biologically relevant C-fused bicyclic β-lactams and β-lactam-based hybrids are discussed.

      PubDate: 2016-09-18T11:40:06Z
       
  • Foreword
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Gordon W. Gribble, John A. Joule


      PubDate: 2016-09-18T11:40:06Z
       
  • Editorial Advisory Board Members Progress in Heterocyclic Chemistry
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28


      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 5.3 Five-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Zhihai Ke, Gavin Chit Tsui, Xiao-Shui Peng, Ying-Yeung Yeung
      Papers published in 2015 on reactions and syntheses of furans, tetrahydrofurans, benzo[b]furan, dihydrobenzo[b]furan, benzo[c]furan, and their derivatives are reviewed in this chapter.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 5.4 Five-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Larry Yet
      The synthesis and chemistry of pyrazoles, imidazoles, 1,2,3-triazoles, 1,2,4-triazoles, and tetrazoles were actively pursued in 2015. No attempt was made to incorporate all the exciting chemistry and biological applications that were published in 2015.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 5.5 Five-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Yong-Jin Wu
      This review chapter describes the syntheses and reactions of five-membered heterocyclic ring systems containing nitrogen and sulfur (reported during 2015). The importance of these p-rich heterocycles in medicinal chemistry and natural products is also covered.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 5.6 Five-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): R. Alan Aitken, Graziella-Ioana Dragomir
      This review covers work published in the calendar year 2015. The synthesis and reaction chemistry of five-membered heterocycles containing two oxygen atoms, two sulfur atoms, or an oxygen and a sulfur are reviewed.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 5.7 Five-Membered Ring Systems With O and N Atoms
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Franca M. Cordero, Donatella Giomi, Luisa Lascialfari
      This review covers work published in the calendar year 2015. Novel reaction chemistry and new ring synthetic methods for isoxazoles, isoxazolines, isoxazolidines, oxazoles, oxazolines, oxazolidines, and oxadiazoles are reviewed.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 6.1 Six-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Gordon W. Gribble, Tara L.S. Kishbaugh
      The syntheses and reactions of the pi-deficient heterocycles, pyridines, quinolines, isoquinolines, and the corresponding N-oxides, reported during 2015 are covered.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 6.2 Six-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): K. Alison Rinderspacher
      Found in natural products and frequently used as flavoring agents or as building blocks for pharmaceuticals, diazines and their benzo derivatives possess a diverse set of properties, allowing a broad range of applications, spanning from medicinal chemistry to electrochemistry. New diazine-based natural products continue to be isolated and studied. In addition, new syntheses, reactions, and applications of diazine-based compounds are reported every year. Recent advances in the development of new preparations, reactions, and applications of diazines and their benzo derivatives as well as the discovery of new diazine-based natural products, published in the literature in 2014, are discussed in this review.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 6.3 Triazines, Tetrazines, and Fused Ring Polyaza Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Pierre Audebert, Gilles Clavier, Clémence Allain
      This chapter describes and resumes the different works that provided real advances in the field of aromatic heterocycles featuring several nitrogen atoms, in the authors' opinion, during the year 2015. It is divided into three main sections, one devoted to triazines, separating the symmetrical triazines (1,3,5-triazines or s-triazines) from the unsymmetrical ones (1,2,4-triazines or a-triazines). A second part is devoted to tetrazines, especially featuring the abundant and more investigated 1,2,4,5-tetrazines or s-tetrazines. Finally, a last shorter section is devoted to less common and higher order rings like heptazines, fused purines, pteridines, and so on. While emphasizing on the original and new synthetic methods and reactions, the chapter also relates briefly the biological applications of these compounds, and also the fast-rising applications in the field of active molecular materials.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 6.4 Six-Membered Ring Systems
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Clementina M.M. Santos, Artur M.S. Silva
      This chapter provides an overview of the most studied transformations on O- and S-6-membered heterocycles published in 2015. Novel methodologies, specific reactions and reagents for the synthesis of pyrans; chromenes and chromans; isochromenes and isochromans; pyranones; coumarins and isocoumarins; chromones and chromanones; xanthenes and xanthones; thiopyrans and analogs; di-, tri-, and tetraoxanes and also oxathianes are highlighted.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 7 Seven-Membered Rings
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): Adam G. Meyer, Jason A. Smith, Christopher Hyland, Charlotte C. Williams, Alex C. Bissember, Thomas P. Nicholls
      This chapter aims to provide an overview of the key synthetic methods, reactions, and applications reported in 2015 in the area of seven-membered heterocyclic compounds. Most of the focus has centered on benzo-derivatives containing at least one N atom, and has been driven by the search for new heterocycles with biological activity and the total synthesis of natural products. New synthetic methods of interest have included transition metal-catalyzed, dipolar cycloaddition, cascade and C-H functionalization processes. The increasing number of reports on the chemistry of heterocyclic compounds containing four or five N, O, or S atoms is also covered.

      PubDate: 2016-09-18T11:40:06Z
       
  • Chapter 8 Eight-Membered and Larger Rings
    • Abstract: Publication date: 2016
      Source:Progress in Heterocyclic Chemistry, Volume 28
      Author(s): George R. Newkome
      This chapter is a review of eight or larger membered macrocyclic rings possessing one or more heteroatoms. Also included is a comprehensive review of related reviews that are of importance to researchers in this topical arena.

      PubDate: 2016-09-18T11:40:06Z
       
 
 
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