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Progress in Heterocyclic Chemistry

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ISSN (Print) 0959-6380
Published by Elsevier

[2565 journals]

Chapter 7 Seven-Membered Rings
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work published in the calendar year 2010. Novel reaction chemistry and new ring synthetic methods for azepines, benzoazepines, oxepines, thiepines, diazepines, benzodiazepines, dioxepines, dithiepines are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.3 Triazines, Tetrazines, and Fused Ring Polyaza Systems
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work published in the calendar year 2010. Novel reaction chemistry and new ring synthetic methods for 1,2,3-triazines, 1,2,4-triazines, 1,3,5-triazines, tetrazines, and purines are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.4 Six-Membered Ring Systems With O and/or S Atoms
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work published in the calendar year 2010. Novel reaction chemistry and new ring synthetic methods for pyrans, [1]benzopyrans, dihydro[1]benzopyrans (chromenes, chromans), [2]benzopyrans, dihydro[2]benzopyrans (isochromenes, isochromans), pyranones, coumarins, chromones, xanthenes, xanthones, thiopyrans, dioxins. dioxanes, trioxanes, tetraoxanes, dithianes, trithianes, oxathianes are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.1 Six-Membered Ring Systems Pyridines and Benzo Derivatives
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  Pyridines, quinolines, and isoquinolines have found a function in almost all aspects of organic chemistry. Pyridine has found use as a solvent, base, ligand, functional group, and molecular scaffold. As structural elements, these moieties are potent electron-deficient groups, metal-directing functionalities, fluorophores, and medicinally important pharmacophores. In the past year, the chemistry of these compounds has been exploited in a range of fields. In synthetic chemistry, azines allow metal-catalyzed CH activation of neighboring carbons. In supramolecular chemistry, pyridines link metal organic frameworks and pyridinium salts provide cationic structures for nanodevices. These structures have found use in biological systems, as revealed by several blockbuster drugs and a host of new natural products. This review discusses novel preparations, reactions, functionalizations, and applications of pyridine, quinoline, and isoquinoline reported during 2010.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.7 Five-Membered Ring Systems with O and N Atoms
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work published in the calendar year 2010. Novel reaction chemistry and new ring synthetic methods for isoxazoles, isoxazolines, isoxazolidines, oxazoles, oxazolines, oxazolidines, oxadiazoles are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.2 Six-Membered Ring Systems Diazines and Benzo Derivatives
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work on diazine research published in the 2010 calendar year. New synthetic methods for the construction of pyridazine-, pyrimidine-, and pyrazine-based ring systems are discussed. Novel reaction chemistry and the application of diazines, including phthalazines, cinnolines, quinazolines, pteridines, quinoxalines, and phenazines are covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.6 Five-Membered Ring Systems With O and S (Se, Te) Atoms
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work published in the calendar year 2010. The synthesis and reaction chemistry of five-membered heterocycles containing two oxygens, oxygen and a sulfur, or two sulfur heteroatoms is reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.5 Five-Membered Ring Systems With N and S (Se) Atoms
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  This chapter focuses on the syntheses and reactions of these five-membered heterocyclic ring systems containing nitrogen and sulfur (or selenium) (reported during 2010). The importance of these p-rich heterocycles in medicinal chemistry and natural products is also covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.3 Five-Membered Ring Systems: Furans and Benzofurans
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The review covers work published in the calendar year 2010. New methods for the ring synthesis of furans, dihydrofurans and tetrahydrofurans, and benzofurans, are discussed. Novel reaction chemistry of furans, dihydrofurans and tetrahydrofurans, and benzofurans, is covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.4 Five-Membered Ring Systems: With More than One N Atom
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The synthesis and chemistry of pyrazoles, imidazoles, 1,2,3-triazoles, 1,2,4-triazoles, and tetrazoles are covered for the year 2010.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.2 Five-Membered Ring Systems Pyrroles and Benzo Analogs
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  The development of methodology for the synthesis and reactions of pyrrole- and indole-based alkaloids continues to be driven by the intriguing molecular architectures and biomedicinal properties of this distinctive class of heterocycles. Examples of pyrrole and indole synthesis have been presented in this chapter using a systematic approach that targets key bond disconnections. Select applications of pyrrole and indole syntheses within the context of natural product total synthesis also appear. The literature reviewed includes seminal reports as well as extensions of established methodologies.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.1 Five-Membered Ring Systems Thiophenes and Se/Te Derivatives
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  This review covers work published in the calendar year 2010. Novel reaction chemistry, new ring synthetic methods, and elaborations for thiophenes, benzothiophenes, selenophenes, and tellurophenes are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 4 Four-Membered Ring Systems
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  This review covers work published in the calendar year 2010. Synthesis of four-membered oxygen- and nitrogen-containing heterocycles is reviewed. New developments in the reaction chemistry of four-membered heterocycles, especially β-lactams, are covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 3 Three-Membered Ring Systems
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  This review covers work published in the calendar year 2010. The synthetic chemistry of three-membered oxygen- and nitrogen-containing heterocycles is reviewed. New developments in the synthesis and reactions of epoxides, aziridines, oxaziridines, and azirines are covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 2 Synthesis of Heterocycles by Palladium-Catalyzed Intramolecular Heteroarylation
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  Synthesis of heterocycles by intramolecular CN bond formation through a palladium-catalyzed Hartwig–Buchwald reaction is described. The review covers the results reported for the synthesis of five- and six-membered rings, as well as medium-size and macro-heterocycles over the past 15 years. The review is organized by the size of the rings formed with further partition into subsections based on number of heteroatoms on the ring or fused ring systems. A separate section deals with tandem CC/CN palladium-catalyzed annulation sequences and cascades.
  
  PubDate: 2012-12-15T09:50:40Z
Editorial Advisory Board Members Progress in Heterocyclic Chemistry
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 1 Recent Advances in the Synthesis of Aspidosperma-Type Alkaloids
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  Aspidosperma alkaloids are complex indole-containing natural products that historically have generated a considerable amount of interest from the synthetic community. Many members of this class are biologically active and replete with functional groups and chiral centers which provide a challenging proving ground for new methodology. This review will highlight recent advances in the total synthesis of molecules such as aspidospermidine, the subincanadines, vinblastine, and haplophytine in the past decade.
  
  PubDate: 2012-12-15T09:50:40Z
Index
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  PubDate: 2012-12-15T09:50:40Z
Series Page
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  PubDate: 2012-12-15T09:50:40Z
Copyright
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 8 Eight-Membered and Larger Rings
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. New syntheses, chemical reactions, and applications of eight-membered and larger ring heterocycles are reviewed, with an emphasis on new structures and material science relevance.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 7 Seven-Membered Rings
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Novel reaction chemistry and new ring synthetic methods for azepines, benzoazepines, oxepines, thiepines, diazepines, benzodiazepines, dioxepines, and dithiepines are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.4 Six-Membered Ring Systems: With O and/or S Atoms
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Novel reaction chemistry and new ring synthetic methods for pyrans, [1]benzopyrans, dihydro[1]benzopyrans (chromenes, chromans), [2]benzopyrans, dihydro[2]benzopyrans (isochromenes, isochromans), pyranones, coumarins, chromones, xanthenes, xanthones, thiopyrans, dioxins, dioxanes, trioxanes, tetraoxanes, dithianes, trithianes, and oxathianes are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.3 Triazines, Tetrazines, and Fused Ring Polyaza Systems
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Novel reaction chemistry and new ring synthetic methods for 1,2,3-triazines, 1,2,4-triazines, 1,3,5-triazines, tetrazines, and purines are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.2 Six-Membered Ring Systems Diazines and Benzo Derivatives
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. New syntheses and novel chemistry of diazines and their benzo-fused derivatives are covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 6.1 Six-Membered Ring Systems: Pyridine and Benzo Derivatives
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  Pyridine, its benzo and pyridine-based compounds play diverse roles in organic chemistry. As ligands, solvents, and catalysts they facilitate reactions; thus descriptions of these new ligands and their applications abound each year. Pyridine-based materials are valued for their optical and physical properties as well as their medical potential. Additionally, pyridine-based natural products continue to be discovered and studied for their properties and to understand their biosynthesis. This review covers the synthesis and functionalization of pyridines and their benzo derivatives (quinolines and isoquinolines) published during 2011; the application of these materials is also highlighted.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.7 Five-Membered Ring Systems with O and N Atoms
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Novel reaction chemistry and new ring synthetic methods for isoxazoles, isoxazolines, isoxazolidines, oxazoles, oxazolines, oxazolidines, and oxadiazoles are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.6 Five-Membered Ring Systems: With O and S (Se, Te) Atoms
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. The synthesis and reaction chemistry of five-membered heterocycles containing two oxygen atoms or an oxygen and a sulfur are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.5 Five-Membered Ring Systems: With N and S (Se) Atoms
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. New syntheses and chemical reactions of the five-membered ring nitrogen–sulfur and nitrogen–selenium heterocycles are reviewed, including those of pharmaceutical interest.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.4 Five-Membered Ring Systems: With More than One N Atom
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. New syntheses and chemistry of those five-membered nitrogen heterocycles containing more than one nitrogen are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.3 Five-Membered Ring Systems: Furans and Benzofurans
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Naturally occurring furans, dihydrofurans, and tetrahydrofurans are summarized. New methods for the ring synthesis of furans, dihydrofurans and tetrahydrofurans, and benzofurans are discussed. Novel reaction chemistry of furans, dihydrofurans and tetrahydrofurans, and benzofurans is covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.2 Five-Membered Ring Systems Pyrroles and Benzo Analogs
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The synthesis and reactions of pyrroles, indoles, isoindoles, and related fused heterocyclic ring systems from the year 2011 are reviewed in this monograph. Pyrroles and indoles are treated in separate sections; ring forming reactions are discussed by bond disconnection. Other sections include reactivity of the parent rings, reactions of side chains, C–H activation, and examples in total synthesis.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 5.1 Five-Membered Ring Systems Thiophenes and Se/Te Derivatives
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. New syntheses and reactions of thiophenes, benzothiophenes, selenophenes, and tellurophenes, including the medicinal chemistry and material science applications of thiophenes, selenophenes, and tellurophenes, are reviewed.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 4 Four-Membered Ring Systems
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Synthesis of four-membered oxygen- and nitrogen-containing heterocycles is reviewed. New developments in the reaction chemistry of four-membered heterocycles, especially β-lactams, are covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 3 Three-Membered Ring Systems
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers work published in the calendar year 2011. Synthesis and reactions of oxiranes (epoxides) and aziridines are covered.
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 2 Progress in Quinoxaline Synthesis (Part 1)
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  In this two-part review (Part 2 to be published in Progress in Heterocyclic Chemistry, Volume 25), recent advances in the synthesis of quinoxalines are reviewed. Medicinal compounds containing a quinoxaline moiety are also covered. The review covers condensations of 1,2-diaminoarenes, condensations of o-benzoquinone diimines and diimides, syntheses from anilines, syntheses from various other heterocycles, and syntheses from 3,3,6,6-tetrachloro-1,2-cyclohexanedione.
  
  PubDate: 2012-12-15T09:50:40Z
Editorial Advisory Board Members Progress in Heterocyclic Chemistry
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 1 Heterocycles and Medicine A Survey of the Heterocyclic Drugs Approved by the U.S. FDA from 2000 to Present
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  The review covers drugs that have been approved by the U.S. Food and Drug Administration during the period 2000 to the present time that contains heterocyclic rings. Some 57% of the drugs currently in use contain at least one heterocycle.
  
  PubDate: 2012-12-15T09:50:40Z
Foreword
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  PubDate: 2012-12-15T09:50:40Z
Copyright
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  PubDate: 2012-12-15T09:50:40Z
Series Page
- Abstract: 2012
  Publication year: 2012
  Source:Progress in Heterocyclic Chemistry, Volume 24
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 8 Eight-Membered and Larger Rings
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  This review covers meso- and macrocycles possessing heteroatoms and/or subheterocyclic rings excluding those possessing lactone, lactams, and cyclic imides and having a literature appearance in 2010. The specific heteromacrocycles contain combinations of carbon with nitrogen, oxygen, sulfur, silicon, phosphorus, arsenic, antimony, and/or bismuth. There is also a yearly review of related reviews covering the supramolecular chemistry at the macro- and nanomolecular levels.
  
  PubDate: 2012-12-15T09:50:40Z
Index
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 23
  
  PubDate: 2012-12-15T09:50:40Z
Series Editors
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z
Copyright
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z
Foreword
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z
Series Editors
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 1 Recent Advances in the C-2 Regioselective Direct Arylation of Indoles
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 2 Heterocyclic Dyes: Preparation, Properties, and Applications
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z
Chapter 3 Three-Membered Ring Systems
- Abstract: 2011
  Publication year: 2011
  Source:Progress in Heterocyclic Chemistry, Volume 22
  
  PubDate: 2012-12-15T09:50:40Z