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  Subjects -> BIOLOGY (Total: 3172 journals)
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BIOLOGY (1511 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 1720 Journals sorted alphabetically
AAPS Journal     Hybrid Journal   (Followers: 21)
Achievements in the Life Sciences     Open Access   (Followers: 5)
ACS Synthetic Biology     Hybrid Journal   (Followers: 25)
Acta Biologica Colombiana     Open Access   (Followers: 7)
Acta Biologica Hungarica     Full-text available via subscription   (Followers: 4)
Acta Biologica Sibirica     Open Access   (Followers: 1)
Acta Biomaterialia     Hybrid Journal   (Followers: 27)
Acta Biotheoretica     Hybrid Journal   (Followers: 4)
Acta Chiropterologica     Full-text available via subscription   (Followers: 6)
acta ethologica     Hybrid Journal   (Followers: 4)
Acta Fytotechnica et Zootechnica     Open Access   (Followers: 1)
Acta Limnologica Brasiliensia     Open Access   (Followers: 3)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Musei Silesiae, Scientiae Naturales     Open Access  
Acta Neurobiologiae Experimentalis     Open Access  
Acta Parasitologica     Hybrid Journal   (Followers: 10)
Acta Scientiarum. Biological Sciences     Open Access   (Followers: 2)
Acta Scientifica Naturalis     Open Access   (Followers: 3)
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis     Open Access  
Actualidades Biológicas     Open Access   (Followers: 1)
Advanced Health Care Technologies     Open Access   (Followers: 4)
Advanced Journal of Graduate Research     Open Access  
Advanced Nonlinear Studies     Hybrid Journal  
Advanced Studies in Biology     Open Access  
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 2)
Advances in Bioinformatics     Open Access   (Followers: 17)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4)
Advances in Biology     Open Access   (Followers: 9)
Advances in Biosensors and Bioelectronics     Open Access   (Followers: 7)
Advances in Cell Biology/ Medical Journal of Cell Biology     Open Access   (Followers: 25)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 12)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Ecological Research     Full-text available via subscription   (Followers: 44)
Advances in Environmental Sciences - International Journal of the Bioflux Society     Open Access   (Followers: 16)
Advances in Enzyme Research     Open Access   (Followers: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Genome Biology     Full-text available via subscription   (Followers: 8)
Advances in High Energy Physics     Open Access   (Followers: 19)
Advances in Human Biology     Open Access   (Followers: 3)
Advances in Life Science and Technology     Open Access   (Followers: 16)
Advances in Life Sciences     Open Access   (Followers: 6)
Advances in Marine Biology     Full-text available via subscription   (Followers: 18)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 23)
Advances in Organ Biology     Full-text available via subscription   (Followers: 1)
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3)
Advances in Regenerative Biology     Open Access   (Followers: 1)
Advances in Space Biology and Medicine     Full-text available via subscription   (Followers: 6)
Advances in Structural Biology     Full-text available via subscription   (Followers: 5)
Advances in Virus Research     Full-text available via subscription   (Followers: 5)
African Journal of Range & Forage Science     Hybrid Journal   (Followers: 6)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 1)
Ageing Research Reviews     Hybrid Journal   (Followers: 11)
Aging Cell     Open Access   (Followers: 16)
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat     Open Access  
AJP Cell Physiology     Hybrid Journal   (Followers: 15)
AJP Endocrinology and Metabolism     Hybrid Journal   (Followers: 24)
AJP Lung Cellular and Molecular Physiology     Hybrid Journal   (Followers: 3)
Al-Kauniyah : Jurnal Biologi     Open Access  
Alasbimn Journal     Open Access   (Followers: 1)
Alces : A Journal Devoted to the Biology and Management of Moose     Open Access  
AMB Express     Open Access   (Followers: 1)
Ambix     Hybrid Journal   (Followers: 3)
American Biology Teacher     Full-text available via subscription   (Followers: 14)
American Fern Journal     Full-text available via subscription   (Followers: 1)
American Journal of Agricultural and Biological Sciences     Open Access   (Followers: 8)
American Journal of Bioethics     Hybrid Journal   (Followers: 12)
American Journal of Human Biology     Hybrid Journal   (Followers: 14)
American Journal of Medical and Biological Research     Open Access   (Followers: 8)
American Journal of Plant Sciences     Open Access   (Followers: 19)
American Journal of Primatology     Hybrid Journal   (Followers: 15)
American Malacological Bulletin     Full-text available via subscription   (Followers: 3)
American Naturalist     Full-text available via subscription   (Followers: 74)
Amphibia-Reptilia     Hybrid Journal   (Followers: 6)
Anadolu University Journal of Science and Technology : C Life Sciences and Biotechnology     Open Access  
Anaerobe     Hybrid Journal   (Followers: 4)
Analytical Methods     Full-text available via subscription   (Followers: 11)
Anatomical Science International     Hybrid Journal   (Followers: 3)
Animal Cells and Systems     Hybrid Journal   (Followers: 4)
Animal Models and Experimental Medicine     Open Access  
Annales de Limnologie - International Journal of Limnology     Hybrid Journal   (Followers: 1)
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annales Henri Poincaré     Hybrid Journal   (Followers: 3)
Annals of Applied Biology     Hybrid Journal   (Followers: 7)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 17)
Annals of Human Biology     Hybrid Journal   (Followers: 5)
Annals of Science and Technology     Open Access  
Annual Review of Biomedical Engineering     Full-text available via subscription   (Followers: 14)
Annual Review of Biophysics     Full-text available via subscription   (Followers: 23)
Annual Review of Cancer Biology     Full-text available via subscription   (Followers: 2)
Annual Review of Cell and Developmental Biology     Full-text available via subscription   (Followers: 37)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 13)
Annual Review of Genomics and Human Genetics     Full-text available via subscription   (Followers: 24)
Annual Review of Phytopathology     Full-text available via subscription   (Followers: 12)
Anthropological Review     Open Access   (Followers: 23)
Anti-Infective Agents     Hybrid Journal   (Followers: 3)
Antibiotics     Open Access   (Followers: 9)
Antioxidants     Open Access   (Followers: 4)
Antioxidants & Redox Signaling     Hybrid Journal   (Followers: 8)
Antonie van Leeuwenhoek     Hybrid Journal   (Followers: 5)
Anzeiger für Schädlingskunde     Hybrid Journal   (Followers: 1)
Apidologie     Hybrid Journal   (Followers: 4)
Apmis     Hybrid Journal   (Followers: 1)
APOPTOSIS     Hybrid Journal   (Followers: 8)
Applied Bionics and Biomechanics     Open Access   (Followers: 8)
Applied Vegetation Science     Full-text available via subscription   (Followers: 10)
Aquaculture Environment Interactions     Open Access   (Followers: 4)
Aquaculture International     Hybrid Journal   (Followers: 25)
Aquaculture Reports     Open Access   (Followers: 3)
Aquaculture, Aquarium, Conservation & Legislation - International Journal of the Bioflux Society     Open Access   (Followers: 7)
Aquatic Biology     Open Access   (Followers: 6)
Aquatic Ecology     Hybrid Journal   (Followers: 35)
Aquatic Ecosystem Health & Management     Hybrid Journal   (Followers: 15)
Aquatic Science and Technology     Open Access   (Followers: 3)
Aquatic Toxicology     Hybrid Journal   (Followers: 23)
Archaea     Open Access   (Followers: 3)
Archiv für Molluskenkunde: International Journal of Malacology     Full-text available via subscription   (Followers: 3)
Archives of Biological Sciences     Open Access  
Archives of Microbiology     Hybrid Journal   (Followers: 9)
Archives of Natural History     Hybrid Journal   (Followers: 6)
Archives of Oral Biology     Hybrid Journal   (Followers: 2)
Archives of Virology     Hybrid Journal   (Followers: 5)
Archivum Immunologiae et Therapiae Experimentalis     Hybrid Journal   (Followers: 2)
Arid Ecosystems     Hybrid Journal   (Followers: 2)
Arquivos do Instituto Biológico     Open Access   (Followers: 1)
Arquivos do Museu Dinâmico Interdisciplinar     Open Access  
Arthropod Structure & Development     Hybrid Journal   (Followers: 2)
Arthropods     Open Access   (Followers: 1)
Artificial DNA: PNA & XNA     Hybrid Journal   (Followers: 3)
Asian Bioethics Review     Full-text available via subscription   (Followers: 3)
Asian Journal of Biodiversity     Open Access   (Followers: 4)
Asian Journal of Biological Sciences     Open Access   (Followers: 3)
Asian Journal of Cell Biology     Open Access   (Followers: 5)
Asian Journal of Developmental Biology     Open Access   (Followers: 2)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 4)
Asian Journal of Nematology     Open Access   (Followers: 4)
Asian Journal of Poultry Science     Open Access   (Followers: 4)
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche     Open Access  
Australian Life Scientist     Full-text available via subscription   (Followers: 2)
Australian Mammalogy     Hybrid Journal   (Followers: 6)
Autophagy     Hybrid Journal   (Followers: 3)
Avian Biology Research     Full-text available via subscription   (Followers: 4)
Avian Conservation and Ecology     Open Access   (Followers: 11)
Bacteriology Journal     Open Access   (Followers: 1)
Bacteriophage     Full-text available via subscription   (Followers: 3)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Plant Taxonomy     Open Access  
Bangladesh Journal of Scientific Research     Open Access   (Followers: 1)
Batman Üniversitesi Yaşam Bilimleri Dergisi     Open Access  
Berita Biologi     Open Access   (Followers: 1)
Between the Species     Open Access   (Followers: 1)
Bio Tribune Magazine     Hybrid Journal  
BIO Web of Conferences     Open Access  
BIO-Complexity     Open Access  
Bio-Grafía. Escritos sobre la Biología y su enseñanza     Open Access  
Bioanalytical Reviews     Hybrid Journal   (Followers: 2)
Biocatalysis and Biotransformation     Hybrid Journal   (Followers: 6)
BioCentury Innovations     Full-text available via subscription   (Followers: 1)
Biochemistry and Cell Biology     Hybrid Journal   (Followers: 16)
Biochimie     Hybrid Journal   (Followers: 7)
BioControl     Hybrid Journal   (Followers: 5)
Biocontrol Science and Technology     Hybrid Journal   (Followers: 5)
Biodemography and Social Biology     Hybrid Journal  
BioDiscovery     Open Access   (Followers: 2)
Biodiversitas : Journal of Biological Diversity     Open Access  
Biodiversity Data Journal     Open Access   (Followers: 4)
Biodiversity Informatics     Open Access   (Followers: 1)
Biodiversity Information Science and Standards     Open Access  
Biodiversity: Research and Conservation     Open Access   (Followers: 27)
Bioedukasi : Jurnal Pendidikan Biologi FKIP UM Metro     Open Access  
Bioeksperimen : Jurnal Penelitian Biologi     Open Access  
Bioelectrochemistry     Hybrid Journal   (Followers: 2)
Bioelectromagnetics     Hybrid Journal   (Followers: 1)
Bioenergy Research     Hybrid Journal   (Followers: 3)
Bioengineering and Bioscience     Open Access   (Followers: 1)
BioEssays     Hybrid Journal   (Followers: 10)
Bioethics     Hybrid Journal   (Followers: 15)
BioéthiqueOnline     Open Access  
Biofabrication     Hybrid Journal   (Followers: 4)
Biofilms     Full-text available via subscription   (Followers: 1)
Biogeosciences (BG)     Open Access   (Followers: 10)
Biogeosciences Discussions (BGD)     Open Access   (Followers: 2)
Bioinformatics     Hybrid Journal   (Followers: 310)
Bioinformatics and Biology Insights     Open Access   (Followers: 11)
Bioinspiration & Biomimetics     Hybrid Journal   (Followers: 7)
Biointerphases     Open Access   (Followers: 1)
Biojournal of Science and Technology     Open Access  
BioLink : Jurnal Biologi Lingkungan, Industri, Kesehatan     Open Access   (Followers: 1)
Biologia     Hybrid Journal  
Biologia on-line : Revista de divulgació de la Facultat de Biologia     Open Access  
Biological Bulletin     Partially Free   (Followers: 6)
Biological Control     Hybrid Journal   (Followers: 4)
Biological Invasions     Hybrid Journal   (Followers: 20)
Biological Journal of the Linnean Society     Hybrid Journal   (Followers: 18)
Biological Letters     Open Access   (Followers: 5)
Biological Procedures Online     Open Access  
Biological Psychiatry     Hybrid Journal   (Followers: 48)
Biological Psychology     Hybrid Journal   (Followers: 7)
Biological Research     Open Access  

        1 2 3 4 5 6 7 8 | Last

Journal Cover
Anadolu University Journal of Science and Technology : C Life Sciences and Biotechnology
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2146-0264 - ISSN (Online) 2146-0213
Published by Anadolu University Homepage  [4 journals]
  • The Uses of Stem Cells in Toxicology Studies

    • Authors: Can Özgür YALÇIN; Sezen Yılmaz
      Abstract: Stem cells arecurrently being used in drug/toxicity screenings, investigation of diseasepathways and mechanistic studies such as developmental toxicity. Human-inducedpluripotent stem cells (iPSC) can be obtained by manipulation of pluripotencygenes from differentiated, mature and specialized cells, and thus the toxicitycaused by environmental exposure can be determined, as well as reflecting thegenetic structure of the individual. Pathways underlying disease and toxicityconditions can be illuminated by identifying genomic, proteomic, transcriptomicand metabolomic patterns of human embryonic stem cells (hESC) and iPSC extensively.Although technological challenges and ethical restrictions prevent common use,the use of human stem cell-based systems in drug discovery and toxicity studiesallows reducing cost and experimental animal use, making safer personalizedmedicine and more accurate risk assessments for environmental toxicants. Inthis review, the use of stem cells in toxicology studies has been mentioned.
      PubDate: Sat, 31 Mar 2018 00:00:00 +030
       
  • BIOACTIVITY RESEARCHING ON NEW SPECIES OF ECHINOPS L. (ASTERACEAE):
           ANTIMICROBIAL AND ANTIOXIDANT ACTIVITY OF ECHINOPS ANTALYENSIS

    • Authors: Handan ŞAPCI; Cem Vural
      Abstract: The aim of this study was to investigate theantimicrobial and antioxidant activities of different extracts from Echinops antayensis C.Vural.Antimicrobial activity was estimated against several common human pathogenicbacterial strains using the agar disc diffusion and minimal inhibitoryconcentration assays. Antioxidant activity was evaluated using the DPPHradical-scavenging assay and total phenolic content methods. On the light ofthese experiments, E. antalyensiswould seem to be an important natural antioxidant. This study is first reporton the biological activity of E.antalyensis as regarded new species from Turkey.
      PubDate: Sat, 31 Mar 2018 00:00:00 +030
       
  • Determination of Antimicrobial Activity and Some Metabolic Properties of
           Lactic Acid Bacteria Isolated from Table Fermented Olives (Olea europaea
           L.)

    • Authors: Merih KIVANÇ; Şerife Yelda Erikçi
      Abstract: The olive (Oleaeuropaea L.) is consumed extensively in the world and in our country; ithas great value for nutrition. Today, the importance of the olive is increasingwith the trend towards of natural food.In this study, the antimicrobial activity and some metabolic properties oflactic acid bacteria isolated from fermented commercial and home product olivesamples produced in our country were determined. Fifty lactic acid bacteriawere isolated from ten green table olives and 10 black table olives. Theantimicrobial effect of these isolates was determined by the agar diffusionmethod and the sandwich overlay method. Effective isolates were identified andtheir lactic acid, hydrogen peroxide and proteolytic activities were determined.Six isolates had antimicrobial activity, from those SZ5 was identified as L. plantarum, DZ2 as E. facium, EZ8, BZ1, SZ1 and BZ4isolates were identified as L. brevis.The pH range of lactic acid bacteria was 5.3 to 6.8 and the lactic acid levelsranged from 0.261 to 1.818 mg / mL. Amounts of proteolytic activity variedbetween 0.003-0.011 tirosine mg / mL and hydrogen peroxide levels variedbetween 0.218-0.96mg / mL. In conclusion, L. brevis SZ1, E. faecium DZ2 and L.brevis BZ1 isolates were identified as candidates for starter culture due totheir ability to grow in high salt concentrations and low pH and their propertyto produce high lactic acid.
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • Comparative Growth Media Performances on in vitro Propagation of Some
           Salep Orchids

    • Authors: Yasemin Kemeç Hürkan; Kaan Hürkan, Cüneyt Akı
      Abstract: Due to theincreasing demand and over collection of orchids from nature to produce salep,scientists have been led to search for more efficient ways to propagate thesespecific orchids in vitro. This present study compares germinationperformances of two commercial (Orchimax and Knudson C) and one speciallyprepared orchid growth media (SV), on economically and medicinally importantorchids used to make salep; (Anacamptis pyramidalis, Dactylorhizaromana, Neotinea tridentata and Anacamptis morio subsp.morio) and further aims to obtain a mature orchid plant by following thenatural environmental cycle. Significantdifferences in seed germination and protocorm development were observed.Asymbiotic germination tests showed that the specially prepared growth mediaperformed better than the commercial media by 79.11% germination rate. Also,that A. morio subsp. morio had the best germination rate by88.91%. Protocorms developed in the sixteenth week after sowing. Soil wascollected from the natural habitat of each species and was used as a pottingsubstrate, and this helped orchids to pass their initial acclimatization stage.Regeneration success of orchids at in vitro conditions could beincreased by using SV growth medium, following their natural hardening offcycle and using specific substrates from their respective habitats.
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • THE EFFECTS OF CALCIUM CARBONATE (CACO3) APPLICATION AT DIFFERENT
           CONCENTRATIONS ON SEED GERMINATION OF DIFFERENT VARIETIES OF CARTHAMUS
           TINCTORIUS L. (ASTERACEAE)

    • Authors: Sema LEBLEBİCİ; Gülçin IŞIK
      Abstract: In this study, twodifferent varieties of Carthamustinctorius L. (Asteraceae) grown for biodiesel production, Remzibey andDinçer seeds were used as study material. The seeds of each variety were letout for germination by placing in calcium carbonate solutions, consisting purewater control, prepared at rates of 2%, 4% , 8%, 15%, 50% and 60%  in Petri dishes, on two-fold drying paper, in16 hours light/8 hours dark photoperiod, at 25 ± 1° C, repeating three times.When the data obtained were analysed statistically, Dinçer variety was foundout to be more resistant to calcium carbonate than Remzibey. Besides, bothtypes of Carthamus tinctorius wereobserved to show better germination in 8% calcium carbonate solution than 4%calcium carbonate. As a result, it can be said that both species of Carthamus tinctorius can germinatebetter in neutral soil and slightly alkaline soil.
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • DEVELOPMENT OF ZEIN-CASEIN MICROCAPSULES FOR ENCAPSULATION OF MINT
           ESSENTIAL OIL

    • Authors: İncilay Gökbulut
      Abstract: In thisstudy, the efficiency and release properties of microcapsules obtained bycoating zein-casein complex at different ratios of mint essential oil have beeninvestigated. Efficiency and release levels of mint essential oil coated withzein and essential oils coated with zein-casein complex were compared. It is plannedto increase their activity by encapsulating the mint essential oil in theapolar structure in capsule form by the hydrophilic / hydrophobic propertieswhich arise from the zein and its amino acids. In thisstudy, casein additions of 1%, 3%, 5%, 7%, 9%, 11%, 13% and 15% were applied tothe zein coating material for mint essential oil microcapsulation. Theefficiency of microencapsulation with only zein as the coating material wasdetermined to be 46%, while the activity value of microencapsulated with 13%with casein-zein formulation was determined at 54.66 %. In addition, in therelease rate test, the release of mint essential oil from the microcapsules wascompleted by providing 42.75% release over 9 days.
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • Lipolytic Activity of Lactic Acid Bacteria Isolated from Turkish
           Pastırma

    • Authors: Emine Dinçer; Merih Kıvanç
      Abstract: Lipases are widely distributedin nature and catalyze the hydrolysis of mono, di and tri acyl glycerols toliberate free fatty acids and glycerol. Various microorganisms produce lipases eitheralone or together with esterase. Lipases form an important group of relevantenzymes and they were used in a variety of biotechnological fields such as food,pharmaceutical, detergent, textile and cosmetic industries. Lipases from lacticacid bacteria may contribute in the development of flavors in foods especiallymeat products. The goal of the present study is to investigate the ability toproduce lipolytic enzymes lactic acid bacteria strains which is selected aspotential probiotics and isolated on pastırma samples in our laboratory todeterminate the possibilities of using as starter cultures in pastırmaproduction. Lipolytic activity of lactic acid bacteria isolated from pastırma hasnot been investigated up to now. The plate assay is performed to screeninglipolytic activity of lactic acid bacteria isolates. In the study, 3 different growthmedium tried and each medium contain tributyrin as a substrate. Using thesemethods, 50 strains of lactic acid bacteria isolated from Turkish pastırma arescreened for the presence of lipolytic activity. As a result of theanalysis, the lipolytic activity is observed in 26 tested strains. Lactobacillus plantarum have highestlipolytic activity.  
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • REDESCRIPTION OF THE TWO HARPACTEA BRISTOWE, 1939 (ARANEAE, DYSDERIDAE)
           SPECIES KNOWN FROM TURKEY

    • Authors: Recep Sulhi ÖZKÜTÜK; Ersen Aydın Yağmur, Kadir Boğaç Kunt, Gizem Karakaş Karakaş Kılıç, Mert Elverici
      Abstract: During our field studies to determine the Harpacteinaae fauna of Turkey, additional samples of Harpactea erseni and H. pugio species described on malespecies were collected; detailed photographs constituting taxonomic charactersof the reproductive organs of both male and female species were given anddescriptions were made and distribution of the species was shown on the map. H. erseni belongs to the rubicunda (D) group which is defined for the genus, by the male reproductiveorgans and some other characters. However, the newly described femalereproductive organ is closely related to the lepida (C) group becausethe posterior spermatheca is completely sclerotized. This situation isdiscussed in the article. H. pugiohas been evaluated in the rubicunda (D) group due to posterior diverticulum inthe crusted posterior spermatheca of the female reproductive organ and thetaxonomic characteristics of the both sexes
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • SİVAS’IN SOLAR TUZLALARINDAKİ MİKROBİYAL TOPLULUKLARIN
           KÜLTÜR-BAĞIMLI KARAKTERİZASYONU

    • Authors: Mehmet Burçin Mutlu; Seval Çınar
      Abstract: Bu çalışmada Sivas’tabulunan farklı solar tuzlalardan halofilik mikroorganizmaların izolasyonu yapılmıştırve elde edilen izolatların 16S rRNA gen analizine dayalı karakterizasyonugerçekleştirilmiştir. İzolasyon işlemi farklı tuz konsantrasyonları ilehazırlanmış 5 farklı besiyeri ile gerçekleştirilmiştir. Morfolojik olarakfarklılık gösteren kolonilerin 16S rRNA genleri ARDRA ile analiz edilmiştir vekesim profilleri karşılaştırılmıştır. 47 adet suş tanımlama amacıylaseçilmiştir. Bacteria domainiiçerisinde yer alan izolatların Idiomarina, Salinivibrio, Halomonas, Salinibacter, Gracilibacillus, Thalassobacillus,Aliifodinibius, Chromohalobacter, Planococcus, Marinobacter, Bacillus, Aquisalimonas, Marinococcus, Alkalibacillus,Kangiella ve Microbulbifer cinsleri ile filogenetik olarak ilişkili olduğu saptanmıştır.Halofilik arke izolatları ise Haloferax, Natrinema, Haloterrigena, Halopelagius,Halorhabdus ve Haloarcula cinsleri içerisinde dağılım göstermiştir.
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
  • ATTRACTIVE APPROACHES in DRUG DELIVERY: BIO-BASED CARRIERS for siRNA
           TARGETING

    • Authors: Zülal Yalınca; Şükrü Tüzmen
      Abstract: Functionalcharacterization of genes can be determined by disruption of gene expression.This provides powerful approach in designing novel treatment strategies. RNAinterference (RNAi) is a natural phenomenon that can aid in the study ofpost-transcriptional regulation of genes. This mechanism can be stimulated viaintroduction of double stranded RNA (dsRNA) in a cell. Synthetic short/small interferingRNAs (siRNA) can be utilized to trigger down-regulation of desired genes viatransfecting into mammalian cells. Recently, utilization of bio-based polymershas been an attractive approach in drug delivery for medical applications. Thisreview article describes the advantages of exploiting bio-based polymericcarriers for siRNA targeting, as bio-therapeutics. Here, we report the currentdevelopments, safety and delivery of bio-based siRNAs via polymeric carriers.Additionally, cancer genetics and metabolic disorders including obesity anddiabetes pertaining to the progress in clinical applications have beenhighlighted.
      PubDate: Wed, 28 Feb 2018 00:00:00 +030
       
 
 
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