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  Subjects -> BIOLOGY (Total: 3153 journals)
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BIOLOGY (1504 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 1720 Journals sorted alphabetically
AAPS Journal     Hybrid Journal   (Followers: 22)
Achievements in the Life Sciences     Open Access   (Followers: 5)
ACS Synthetic Biology     Hybrid Journal   (Followers: 25)
Acta Biologica Colombiana     Open Access   (Followers: 7)
Acta Biologica Hungarica     Full-text available via subscription   (Followers: 4)
Acta Biologica Sibirica     Open Access   (Followers: 1)
Acta Biomaterialia     Hybrid Journal   (Followers: 27)
Acta Biotheoretica     Hybrid Journal   (Followers: 4)
Acta Chiropterologica     Full-text available via subscription   (Followers: 6)
acta ethologica     Hybrid Journal   (Followers: 4)
Acta Fytotechnica et Zootechnica     Open Access   (Followers: 1)
Acta Limnologica Brasiliensia     Open Access   (Followers: 3)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Musei Silesiae, Scientiae Naturales     Open Access  
Acta Neurobiologiae Experimentalis     Open Access  
Acta Parasitologica     Hybrid Journal   (Followers: 10)
Acta Scientiarum. Biological Sciences     Open Access   (Followers: 2)
Acta Scientifica Naturalis     Open Access   (Followers: 3)
Acta Universitatis Agriculturae et Silviculturae Mendelianae Brunensis     Open Access  
Actualidades Biológicas     Open Access   (Followers: 1)
Advanced Health Care Technologies     Open Access   (Followers: 4)
Advanced Journal of Graduate Research     Open Access  
Advanced Studies in Biology     Open Access  
Advances in Antiviral Drug Design     Full-text available via subscription   (Followers: 2)
Advances in Bioinformatics     Open Access   (Followers: 17)
Advances in Biological Regulation     Hybrid Journal   (Followers: 4)
Advances in Biology     Open Access   (Followers: 9)
Advances in Biosensors and Bioelectronics     Open Access   (Followers: 7)
Advances in Cell Biology/ Medical Journal of Cell Biology     Open Access   (Followers: 25)
Advances in Cellular and Molecular Biology of Membranes and Organelles     Full-text available via subscription   (Followers: 12)
Advances in Developmental Biology     Full-text available via subscription   (Followers: 12)
Advances in DNA Sequence-Specific Agents     Full-text available via subscription   (Followers: 5)
Advances in Ecological Research     Full-text available via subscription   (Followers: 44)
Advances in Environmental Sciences - International Journal of the Bioflux Society     Open Access   (Followers: 17)
Advances in Enzyme Research     Open Access   (Followers: 10)
Advances in Experimental Biology     Full-text available via subscription   (Followers: 7)
Advances in Genome Biology     Full-text available via subscription   (Followers: 8)
Advances in High Energy Physics     Open Access   (Followers: 19)
Advances in Human Biology     Open Access   (Followers: 3)
Advances in Life Science and Technology     Open Access   (Followers: 16)
Advances in Life Sciences     Open Access   (Followers: 6)
Advances in Marine Biology     Full-text available via subscription   (Followers: 17)
Advances in Molecular and Cell Biology     Full-text available via subscription   (Followers: 22)
Advances in Organ Biology     Full-text available via subscription   (Followers: 1)
Advances in Planar Lipid Bilayers and Liposomes     Full-text available via subscription   (Followers: 3)
Advances in Regenerative Biology     Open Access   (Followers: 1)
Advances in Space Biology and Medicine     Full-text available via subscription   (Followers: 6)
Advances in Structural Biology     Full-text available via subscription   (Followers: 5)
Advances in Virus Research     Full-text available via subscription   (Followers: 5)
African Journal of Range & Forage Science     Hybrid Journal   (Followers: 6)
AFRREV STECH : An International Journal of Science and Technology     Open Access   (Followers: 1)
Ageing Research Reviews     Hybrid Journal   (Followers: 11)
Aging Cell     Open Access   (Followers: 16)
Agrokémia és Talajtan     Full-text available via subscription   (Followers: 2)
Agrokreatif Jurnal Ilmiah Pengabdian kepada Masyarakat     Open Access  
AJP Cell Physiology     Hybrid Journal   (Followers: 15)
AJP Endocrinology and Metabolism     Hybrid Journal   (Followers: 24)
AJP Lung Cellular and Molecular Physiology     Hybrid Journal   (Followers: 3)
Al-Kauniyah : Jurnal Biologi     Open Access  
Alasbimn Journal     Open Access   (Followers: 1)
Alces : A Journal Devoted to the Biology and Management of Moose     Open Access  
AMB Express     Open Access   (Followers: 1)
Ambix     Hybrid Journal   (Followers: 3)
American Biology Teacher     Full-text available via subscription   (Followers: 14)
American Fern Journal     Full-text available via subscription   (Followers: 1)
American Journal of Agricultural and Biological Sciences     Open Access   (Followers: 8)
American Journal of Bioethics     Hybrid Journal   (Followers: 12)
American Journal of Human Biology     Hybrid Journal   (Followers: 14)
American Journal of Medical and Biological Research     Open Access   (Followers: 8)
American Journal of Plant Sciences     Open Access   (Followers: 19)
American Journal of Primatology     Hybrid Journal   (Followers: 15)
American Malacological Bulletin     Full-text available via subscription   (Followers: 3)
American Naturalist     Full-text available via subscription   (Followers: 74)
Amphibia-Reptilia     Hybrid Journal   (Followers: 6)
Anadolu University Journal of Science and Technology : C Life Sciences and Biotechnology     Open Access  
Anaerobe     Hybrid Journal   (Followers: 4)
Analytical Methods     Full-text available via subscription   (Followers: 11)
Anatomical Science International     Hybrid Journal   (Followers: 3)
Animal Cells and Systems     Hybrid Journal   (Followers: 4)
Animal Models and Experimental Medicine     Open Access  
Annales de Limnologie - International Journal of Limnology     Hybrid Journal   (Followers: 1)
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annales Henri Poincaré     Hybrid Journal   (Followers: 3)
Annals of Applied Biology     Hybrid Journal   (Followers: 7)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Human Biology     Hybrid Journal   (Followers: 5)
Annals of Science and Technology     Open Access  
Annual Review of Biomedical Engineering     Full-text available via subscription   (Followers: 14)
Annual Review of Biophysics     Full-text available via subscription   (Followers: 23)
Annual Review of Cancer Biology     Full-text available via subscription   (Followers: 2)
Annual Review of Cell and Developmental Biology     Full-text available via subscription   (Followers: 37)
Annual Review of Food Science and Technology     Full-text available via subscription   (Followers: 13)
Annual Review of Genomics and Human Genetics     Full-text available via subscription   (Followers: 23)
Annual Review of Phytopathology     Full-text available via subscription   (Followers: 12)
Anthropological Review     Open Access   (Followers: 23)
Anti-Infective Agents     Hybrid Journal   (Followers: 3)
Antibiotics     Open Access   (Followers: 9)
Antioxidants     Open Access   (Followers: 4)
Antioxidants & Redox Signaling     Hybrid Journal   (Followers: 8)
Antonie van Leeuwenhoek     Hybrid Journal   (Followers: 5)
Anzeiger für Schädlingskunde     Hybrid Journal   (Followers: 1)
Apidologie     Hybrid Journal   (Followers: 4)
Apmis     Hybrid Journal   (Followers: 1)
APOPTOSIS     Hybrid Journal   (Followers: 8)
Applied Bionics and Biomechanics     Open Access   (Followers: 8)
Applied Vegetation Science     Full-text available via subscription   (Followers: 10)
Aquaculture Environment Interactions     Open Access   (Followers: 3)
Aquaculture International     Hybrid Journal   (Followers: 24)
Aquaculture Reports     Open Access   (Followers: 3)
Aquaculture, Aquarium, Conservation & Legislation - International Journal of the Bioflux Society     Open Access   (Followers: 7)
Aquatic Biology     Open Access   (Followers: 5)
Aquatic Ecology     Hybrid Journal   (Followers: 34)
Aquatic Ecosystem Health & Management     Hybrid Journal   (Followers: 15)
Aquatic Science and Technology     Open Access   (Followers: 3)
Aquatic Toxicology     Hybrid Journal   (Followers: 23)
Archaea     Open Access   (Followers: 3)
Archiv für Molluskenkunde: International Journal of Malacology     Full-text available via subscription   (Followers: 3)
Archives of Biological Sciences     Open Access  
Archives of Microbiology     Hybrid Journal   (Followers: 8)
Archives of Natural History     Hybrid Journal   (Followers: 6)
Archives of Oral Biology     Hybrid Journal   (Followers: 2)
Archives of Virology     Hybrid Journal   (Followers: 5)
Archivum Immunologiae et Therapiae Experimentalis     Hybrid Journal   (Followers: 2)
Arid Ecosystems     Hybrid Journal   (Followers: 2)
Arquivos do Instituto Biológico     Open Access   (Followers: 1)
Arquivos do Museu Dinâmico Interdisciplinar     Open Access  
Arthropod Structure & Development     Hybrid Journal   (Followers: 2)
Arthropods     Open Access   (Followers: 1)
Artificial DNA: PNA & XNA     Hybrid Journal   (Followers: 3)
Asian Bioethics Review     Full-text available via subscription   (Followers: 3)
Asian Journal of Biodiversity     Open Access   (Followers: 4)
Asian Journal of Biological Sciences     Open Access   (Followers: 3)
Asian Journal of Cell Biology     Open Access   (Followers: 5)
Asian Journal of Developmental Biology     Open Access   (Followers: 2)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 4)
Asian Journal of Nematology     Open Access   (Followers: 4)
Asian Journal of Poultry Science     Open Access   (Followers: 4)
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche     Open Access  
Australian Life Scientist     Full-text available via subscription   (Followers: 2)
Australian Mammalogy     Hybrid Journal   (Followers: 6)
Autophagy     Hybrid Journal   (Followers: 2)
Avian Biology Research     Full-text available via subscription   (Followers: 4)
Avian Conservation and Ecology     Open Access   (Followers: 11)
Bacteriology Journal     Open Access   (Followers: 1)
Bacteriophage     Full-text available via subscription   (Followers: 3)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Plant Taxonomy     Open Access  
Bangladesh Journal of Scientific Research     Open Access   (Followers: 1)
Batman Üniversitesi Yaşam Bilimleri Dergisi     Open Access  
Berita Biologi     Open Access   (Followers: 1)
Between the Species     Open Access   (Followers: 1)
Bio Tribune Magazine     Hybrid Journal  
BIO Web of Conferences     Open Access  
BIO-Complexity     Open Access  
Bio-Grafía. Escritos sobre la Biología y su enseñanza     Open Access  
Bioanalytical Reviews     Hybrid Journal   (Followers: 2)
Biocatalysis and Biotransformation     Hybrid Journal   (Followers: 6)
BioCentury Innovations     Full-text available via subscription   (Followers: 1)
Biochemistry and Cell Biology     Hybrid Journal   (Followers: 15)
Biochimie     Hybrid Journal   (Followers: 7)
BioControl     Hybrid Journal   (Followers: 5)
Biocontrol Science and Technology     Hybrid Journal   (Followers: 5)
Biodemography and Social Biology     Hybrid Journal  
BioDiscovery     Open Access   (Followers: 2)
Biodiversitas : Journal of Biological Diversity     Open Access  
Biodiversity Data Journal     Open Access   (Followers: 4)
Biodiversity Informatics     Open Access   (Followers: 1)
Biodiversity Information Science and Standards     Open Access  
Biodiversity: Research and Conservation     Open Access   (Followers: 26)
Bioedukasi : Jurnal Pendidikan Biologi FKIP UM Metro     Open Access  
Bioeksperimen : Jurnal Penelitian Biologi     Open Access  
Bioelectrochemistry     Hybrid Journal   (Followers: 2)
Bioelectromagnetics     Hybrid Journal   (Followers: 1)
Bioenergy Research     Hybrid Journal   (Followers: 2)
Bioengineering and Bioscience     Open Access   (Followers: 1)
BioEssays     Hybrid Journal   (Followers: 10)
Bioethics     Hybrid Journal   (Followers: 15)
BioéthiqueOnline     Open Access  
Biofabrication     Hybrid Journal   (Followers: 5)
Biofilms     Full-text available via subscription   (Followers: 1)
Biogeosciences (BG)     Open Access   (Followers: 10)
Biogeosciences Discussions (BGD)     Open Access   (Followers: 2)
Bioinformatics     Hybrid Journal   (Followers: 305)
Bioinformatics and Biology Insights     Open Access   (Followers: 11)
Bioinspiration & Biomimetics     Hybrid Journal   (Followers: 7)
Biointerphases     Open Access   (Followers: 1)
Biojournal of Science and Technology     Open Access  
BioLink : Jurnal Biologi Lingkungan, Industri, Kesehatan     Open Access  
Biologia     Hybrid Journal  
Biologia on-line : Revista de divulgació de la Facultat de Biologia     Open Access  
Biological Bulletin     Partially Free   (Followers: 6)
Biological Control     Hybrid Journal   (Followers: 4)
Biological Invasions     Hybrid Journal   (Followers: 20)
Biological Journal of the Linnean Society     Hybrid Journal   (Followers: 18)
Biological Letters     Open Access   (Followers: 5)
Biological Procedures Online     Open Access  
Biological Psychiatry     Hybrid Journal   (Followers: 48)
Biological Psychology     Hybrid Journal   (Followers: 6)
Biological Research     Open Access  
Biological Rhythm Research     Hybrid Journal   (Followers: 2)

        1 2 3 4 5 6 7 8 | Last

Journal Cover
Acta Médica Costarricense
Number of Followers: 2  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0001-6002
Published by SciELO Homepage  [718 journals]
  • Día mundial de la trombosis

    •  
  • Cutaneous leishmaniasis in Costa Rica: prevention, diagnosis and treatment

    • Abstract: Resumen El objetivo de esta investigación fue describir el estado actual de la leishmaniosis en Costa Rica, profundizar en las diferentes manifestaciones clínicas y en las especies identificadas a la fecha causantes de la enfermedad, para recomendar tratamientos de acuerdo con estas, así como describir su comportamiento epidemiológico con el propósito de recomendar estrategias de prevención y control en los grupos identificados. Como fuentes de información se utilizaron la base de datos del Registro Colectivo del Ministerio de Salud de Costa Rica, de 2011 a 2016 y las estimaciones de población del Instituto Nacional de Estadísticas y Censos. La incidencia promedio de leishmaniosis en el trienio 2005-07 fue de 35,5 casos por 100 000 y pasó a 30,5 en el trienio 2014-16. Los grupos más afectados fueron los menores de 15 años con: 44,42 casos por cien mil. En San Ramón, Guatuso, Turrialba y Talamanca las tasas de incidencia superan la tasa de incidencia promedio. The purpose of the present research was to describe the different species of Leishmania sp. in Costa Rica so as to recommend specific treatment; also, we wish to describe the epidemiological behavior of the different species in order to suggest prevention and control strategies. Our sources were Collective Registry Data of the Ministry of Health estimates (2011 to 2016) and population data from the National Institute of Statistics and the Census. The average incidence rate from 2005 through 2007 was 35.5 cases per 100,000; the rate went down to 30.5 during the years 2011 through 2016. The most affected age group were those younger than 15 years with a rate of 44.42 per 100,000. Since 2005, the areas in which incidence rates are higher than the average national incidence rate are: San Ramón, Guatuso, Turrialba and Talamanca. Management must be carried out according to: the identified species of the parasite and also according to the experience of experts in Costa Rica. Prevention must be directed to the identified risk groups.
       
  • Factors that affect vaccination against influenza in workers of the
           Department of Nursing

    • Abstract: Resumen Justificación: los programas de inmunización del personal sanitario constituyen una estrategia prioritaria de salud pública con múltiples propósitos, que engloban tanto la protección de los pacientes como de los funcionarios mismos y redundan en un claro beneficio para el empleador. En particular, la vacunación anual contra la influenza en funcionarios de salud representa una medida clave para prevenir la transmisión institucional del virus. A pesar de los esfuerzos por aumentar los índices de cobertura vacunal en este sector, siguen presentándose dudas individuales que inciden en el rechazo de la inmunoprofilaxis por parte de los empleados. El objetivo de este trabajo fue indagar sobre los factores personales, sociales y laborales que propiciaron el rechazo o aceptación de la vacuna contra influenza durante la campaña de inmunización de 2016. Métodos: con el fin de identificar la percepción general y los factores que condicionaron el abstencionismo en torno a la vacunación contra la influenza, se efectuó una encuesta anonima y voluntaria en trabajadores de enfermería del Hospital “Dr. Rafael Ángel Calderón Guardia”, posterior a la campaña de inmunización de 2016. Resultados: la falta de información y los conceptos erróneos en materia de inmunizaciones fueron identificados como factores predominantes asociados con el rechazo a la vacuna. Gran parte de los funcionarios no vacunados tenía factores de riesgo para desarrollar enfermedad grave por influenza y laboraban con pacientes vulnerables a infecciones. Conclusiones: el apoyo y la intensificación de labores educativas de los comités locales de inmunizaciones son necesarios para fomentar el crecimiento de los índices de vacunación del personal de salud. Una estrategia de inmunización obligatoria contra la influenza puede aumentar la cifra de trabajadores vacunados y con ello reducir los casos de infección. Justification: immunization programs for health personnel represent a priority in public health as a prevention strategy. The programs have multiple purposes, which encompass the protection of patients and the officials themselves and result in a clear benefit for the employer. The annual vaccination against influenza in health care professionals represents a key measure to prevent institutional transmission of the virus. Despite efforts realized to increase immunization coverage rates in this sector, rejection of immunoprophylaxis by employees still exists mostly due to individual doubts. The aim of this study was to investigate the personal, social and work related factors that led to the rejection or acceptance of the influenza vaccine during the 2016 immunization campaign. Methods: to identify the general perception and factors which caused abstention related to vaccination against influenza, an anonymous and voluntary survey was conducted on nursing staff of the Dr. Rafael Ángel Calderón Guardia Hospital subsequently to the 2016 influenza immunization campaign. Results: lack of information and misconceptions regarding immunizations were identified as predominant factors associated with the rejection of influenza vaccination. Many unvaccinated individuals had risk factors to develop serious illness due to influenza and worked with patients vulnerable to infections. Conclusions: supporting and intensifying of campaigns focused in the educational work realized by local immunization committees are necessary to elevate vaccination rates of health personnel. A mandatory immunization strategy against influenza may increase the number of vaccinated workers and thereby reduce cases of infection.
       
  • Incidence and Mortality of Thyroid Cancer in Costa Rica, 1990-2014

    • Abstract: Resumen Justificación y objetivo: determinar la incidencia y mortalidad del cáncer de tiroides en Costa Rica 1990-2014. Metodología: investigación descriptiva observacional de corte transversal. El estudio fue realizado en los costarricenses con diagnóstico (7 265 casos nuevos) y muerte (382 defunciones) de cáncer de tiroides, en el periodo 1990-2014. La información se obtuvo de las bases de datos del Centro Centroamericano de la Población, el Instituto Nacional de Estadística y Censo y el Registro Nacional de Tumores, usando los códigos de Clasificación Internacional de Enfermedades 9 y 10. Se hace el cálculo de tasas ajustadas por 100 000 habitantes, porcentajes y años de vida potencialmente perdidos. Resultados: la mortalidad por cáncer de tiroides en Costa Rica mostró una tendencia al ascenso leve durante el periodo de 1990 a 2014. Predomina en el sexo femenino, con una razón de 3:1 y afecta principalmente a la población mayor de 60 años, con tasas mayores en las provincias de Cartago, San José y Heredia. La incidencia, de igual manera, tuvo una tendencia al ascenso, en este caso moderada, al igual que se observó para los años de vida potencialmente perdidos. Conclusión: la mortalidad, la incidencia y los años de vida potencialmente perdidos por cáncer de tiroides en Costa Rica presentan tendencia al ascenso a lo largo del periodo de estudio. Background and Aim : To determine the incidence and mortality of thyroid cancer in Costa Rica from 1990 to 2014. Methodology: descriptive cross-sectional observational research. The study was performed in Costa Ricans with diagnosis (7 265 new cases) and death (382 deaths) of thyroid cancer, in the period 1990-2014. The information was obtained from the databases of the Central American Population Center, the National Institute of Statistics and Census and the National Registry of Tumors, using the International Classification of Diseases 9 and 10. Calculation of adjusted rates by 100 000 inhabitants, percentages and years of life potentially lost was obtained. Results: mortality from thyroid cancer in Costa Rica showed a slight upward trend during the period from 1990 to 2014. It was predominant in females, with a ratio of 3: 1 and affected mainly the population over 60 years old, with higher rates in the provinces of Cartago, San José and Heredia. The incidence, in the same way, had a tendency to rise, moderately, just as it was observed for the years of life potentially lost. Conclusion: Mortality, incidence and years of life potentially lost due to thyroid cancer in Costa Rica present a tendency to rise throughout the study period.
       
  • Use of high flow nasal cannula in infants younger than 24 months in
           general pediatric rooms

    • Abstract: Resumen Justificación y objetivo: la patología respiratoria más frecuente y la principal causa de hospitalización en niños menores de 2 años en Costa Rica y el mundo, es la bronquiolitis. La terapia no invasiva de alto flujo se introdujo en Costa Rica en 2008. El objetivo de este trabajo fue demostrar la utilidad de la cánula de alto flujo en niños menores de 2 años con patología respiratoria. Métodos: estudio transversal observacional en pacientes menores de 2 años que requirieron la colocación de cánula de alto flujo, de julio a octubre de 2015, en el Hospital Nacional de Niños. Resultados: se realizó un análisis de 63 pacientes, con una media de edad de 10 meses y un peso promedio de 8,6 kg. El principal diagnóstico fue bronquiolitis y el germen más común fue metaneumovirus. Se demostró una mejoría estadísticamente significativa en la saturación de oxígeno y el puntaje, luego de la colocación de la cánula de alto flujo (p < 0,05), y disminución de la frecuencia respiratoria (p 0,016) entre los que no requirieron ventilación mecánica asistida, con un valor de siquiera un 30 % menos de la inicial. Hasta un 95 % de los pacientes con una saturación de oxígeno inicial menor al 87 %, ameritó la colocación de ventilación mecánica asistida. La duración promedio de terapia fue de 2 días. De los pacientes estudiados, 16 (25 %) llegaron a requerir ventilación mecánica asistida. Conclusiones: en el grupo analizado, la cánula de alto flujo demostró mejoría en los parámetros clínicos. Los pacientes que ameritaron ventilación mecánica asistida fueron aquellos en donde la mejoría en el puntaje de gravedad fue menor o igual a 2 puntos, o no hubo disminución en la frecuencia respiratoria de al menos un 30 %, y la saturación de oxígeno inicial fue menor al 87 %. Background and aim: Bronquiolitis remains the most common respiratory etiology that affects children under 2 years of age, and the most common cause of hospitalization in this age group. Non-invasive technology with high flow nasal cannula was first introduced in Costa Rica in 2008; the main goal of the study was to demonstrate the utility of this cannula in children under 2 years of age with respiratory disease. Methodology: Transversal observational study, in children under 2 years of age that required high flow nasal cannula therapy, from July to October 2015 in Costa Rica’s main hospital, Hospital Nacional de Niños. Results: a final simple of 63 patients was obtained. The majority came from the central area of the country, with an average age of 10 months and an average weight of 8,6 kg. The main diagnosis was bronquiolitis. The most commonly virus found was the Metaneumovirus. There was a significant improve in the oxygen saturation with the device (p < 0,05) and a significant reduction in respiratory rates (p 0,016) between the children that did not required intubation of at least 30% from the initial value. Up to 95% of the patients with initial oxygen saturation less tan 87% required mechanical ventilation. The average duration of the therapy was of two days. 16 patients (25%) required mechanical ventilation. Conclusions: In Costa Rica, the high flow nasal cannula therapy works and improves clinical parameters. The patients that required intubation were those in which the improvement of the severity scale was of 2 or less points, was no reduction in respiratory rates of at least 30% and the initial oxygen saturation was less than 87%.
       
  • Cochlear Implant: indications

    • Abstract: Resumen Se hace un análisis de las indicaciones de los implantes cocleares, desde su inicio, en donde solo se indicaba en adultos poslocutivos con sordera profunda bilateral de origen coclear. La evolución del implante coclear a través del tiempo y sus buenos resultados, abrieron nuevas indicaciones en diferentes grupos etarios, desde infantes de meses hasta personas de la tercera edad. Igual, incursionó la implantación de ser originalmente solo unilateral a indicarse, en muchos casos, bilateral simultánea o secuencial, obedeciendo a su vez a diferentes tipos de pérdida auditiva neurosensorial de origen coclear, ya sea unilateral o bilateral, y con o sin restos auditivos. An analysis of the indications of cochlear implants is made from its beginning. Initially it was only indicated in post-lingual adults with bilateral deep deafness of cochlear origin. The evolution of the cochlear implant over time and its good results, opened new indications in different age groups, from infants of months to seniors. Likewise, the implantation was originally unilateral, now, in many cases, the indication is bilateral implanted simultaneously or sequential, obeying different types of sensorineural hearing loss of cochlear origin, either unilateral or bilateral, and with or without auditory remains.
       
  • Infection with Zika virus with neurological manifestation

    • Abstract: Resumen El virus del Zika es un flavivirus transmitido por mosquitos Aedes spp, en particular Aedes aegypti. La infección es frecuentemente asintomática y el diagnóstico de este virus se basa en la confirmación por estudios serológicos. Se ha demostrado asociación de la infección de Zika en embarazadas con el desarrollo de microcefalia en el feto, y en adultos con alteraciones neurológicas, principalmente síndrome de Guillain Barré. No existe un tratamiento específico ni una vacuna para la infeccion por el virus del Zika, hasta la fecha. A continuación se reporta el caso de una joven de 14 años, conocida asmática, con manifestaciones clínicas compatibles con infección por un flavivirus y polineuropatía desmielinizante inflamatoria aguda, confirmadas por serología y hallazgos electrofisiológicos. Zika virus is a flavivirus transmitted by Aedes spp. mosquitoes, particularly Aedes aegypti. It´s frequently asymptomatic and the diagnosis of this virus is based on the confirmation of its presence in serological studies. Zika infection has been associated in pregnant women with development of microcephaly in the fetus and in adults with neurological disorders, mainly Guillain Barre Syndrome. At the moment there is no specific treatment or vaccine. We report the case of a young woman 14 years old, with clinical manifestations compatible with a flavivirus and acute inflammatory demyelinating polyneuropathy confirmed by serology and electrophysiological findings.
       
  • Immunotolerance induction in a pediatric hemophilic patient in Costa Rica

    • Abstract: Resumen La hemofilia A es una enfermedad ligada al cromosoma X que predispone al sangrado. Se trata con Factor VIII, ya sea profilaxis o a demanda. La mayoría de países en el resto del mundo utilizan profilaxis, lo cual a la larga es más barato que tratar los pacientes cuando están con un sangrado activo. La producción de inhibidores del factor VIII es la complicación más común y seria del tratamiento. La inmunotolerancia (ITI) es la única opción de tratamiento que ha demostrado satisfactoriamente erradicar esta condición en los pacientes que desarrollan inhibidores, disminuyendo de esta manera no solo los inhibidores sino los costos del tratamiento. Se presenta un caso de inducción satisfactoria de inmunotolerancia con bajas dosis de factor VIII (FVIII) en un paciente pediátrico con hemofilia A severa. A pesar de que la inmunotolerancia se ha practicado antes en Costa Rica, un caso de estos nunca antes había sido publicado. Hemophilia A is an X - linked bleeding disorder. It can be treated with Factor VIII prophylaxis or on demand treatment. Most countries in the world use prophylaxis as it is less expensive than treating patients when they are bleeding. The production of factor VIII inhibitors is the most common and serious complication of the treatment. Immune tolerance induction (ITI) is the only option of treatment when patients develop inhibitors proven to be successful to eradicate this condition, therefore decreasing inhibitors and costs. A case of a successful immune tolerance induction with low doses of factor VIII (FVIII) in a pediatric patient with severe hemophilia A and FVIII inhibitors is presented. Even though inmunotolerance has been practice before in our country, a case like this has never been published.
       
 
 
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