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LABORATORY AND EXPERIMENTAL MEDICINE (98 journals)

Showing 1 - 98 of 98 Journals sorted alphabetically
AAPS PharmSciTech     Hybrid Journal   (Followers: 9)
Actualites Pharmaceutiques     Full-text available via subscription   (Followers: 7)
Adipocyte     Open Access   (Followers: 1)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
American Journal of Experimental and Clinical Research     Open Access   (Followers: 4)
American Journal of Medical and Biological Research     Open Access   (Followers: 11)
Animal Models and Experimental Medicine     Open Access  
Annals of Clinical Chemistry and Laboratory Medicine     Open Access   (Followers: 5)
Applied In Vitro Toxicology     Hybrid Journal   (Followers: 2)
Archives of Clinical and Experimental Medicine     Open Access  
Archives of Medical Research     Hybrid Journal   (Followers: 3)
Archives of Pathology & Laboratory Medicine     Full-text available via subscription   (Followers: 32)
Archives of Preventive Medicine     Open Access   (Followers: 3)
Biomedical Engineering     Hybrid Journal   (Followers: 3)
Bulletin of Experimental Biology and Medicine     Hybrid Journal  
Clinica Chimica Acta     Hybrid Journal   (Followers: 30)
Clinical & Experimental Metastasis     Hybrid Journal  
Clinical and Experimental Medical Journal     Full-text available via subscription   (Followers: 1)
Clinical and Experimental Medicine     Hybrid Journal   (Followers: 4)
Clinical Trials     Hybrid Journal   (Followers: 21)
Clinical Trials in Degenerative Diseases     Open Access  
Clinical Trials in Orthopedic Disorders     Open Access   (Followers: 1)
Current Medicine Research and Practice     Full-text available via subscription  
Current Research in Drug Discovery     Open Access   (Followers: 1)
Drug Design, Development and Therapy     Open Access   (Followers: 4)
Ecography     Hybrid Journal   (Followers: 27)
European Journal of Hospital Pharmacy : Science and Practice (EJHP)     Hybrid Journal   (Followers: 9)
European Journal of Medical Research     Open Access   (Followers: 1)
European Journal of Nanomedicine     Hybrid Journal   (Followers: 1)
Experimental & Molecular Medicine     Open Access   (Followers: 1)
Experimental Aging Research: An International Journal Devoted to the Scientific Study of the Aging Process     Hybrid Journal   (Followers: 3)
Experimental and Therapeutic Medicine     Full-text available via subscription   (Followers: 1)
Experimental Biology and Medicine     Hybrid Journal   (Followers: 3)
Expert Opinion on Drug Delivery     Hybrid Journal   (Followers: 20)
Frontiers in Laboratory Medicine     Open Access  
Frontiers in Medical Technology     Open Access   (Followers: 1)
IN VIVO     Full-text available via subscription   (Followers: 5)
International Archives of Biomedical and Clinical Research     Open Access  
International Journal of Experimental Pathology     Hybrid Journal   (Followers: 1)
International Journal of Health Research and Innovation     Open Access   (Followers: 2)
International Journal of Research in Medical Sciences     Open Access   (Followers: 7)
International Journal of Statistics in Medical Research     Hybrid Journal   (Followers: 5)
Journal of Cell Science & Therapy     Open Access   (Followers: 1)
Journal of Applied Biomaterials & Functional Materials     Hybrid Journal   (Followers: 1)
Journal of Biomedical and Clinical Research     Open Access  
Journal of Clinical Laboratory Analysis     Open Access   (Followers: 14)
Journal of Clinical Medicine and Research     Open Access  
Journal of Clinical Medicine Research     Open Access   (Followers: 4)
Journal of Clinical Trials     Open Access   (Followers: 6)
Journal of Current and Advance Medical Research     Open Access   (Followers: 2)
Journal of Current Medical Research and Practice     Open Access  
Journal of Current Research in Scientific Medicine     Open Access  
Journal of Drug Delivery and Therapeutics JDDT     Open Access   (Followers: 1)
Journal of Enzyme Inhibition and Medicinal Chemistry     Open Access   (Followers: 4)
Journal of Experimental & Clinical Medicine     Full-text available via subscription   (Followers: 1)
Journal of Experimental & Clinical Cancer Research     Open Access   (Followers: 2)
Journal of Experimental and Clinical Medicine     Open Access  
Journal of Experimental Medicine     Full-text available via subscription   (Followers: 46)
Journal of Experimental Pharmacology     Open Access   (Followers: 2)
Journal of Histotechnology     Hybrid Journal   (Followers: 2)
Journal of International Medical Research     Open Access   (Followers: 3)
Journal of Investigative Medicine High Impact Case Reports     Open Access  
Journal of Medicine and Biomedical Research     Open Access   (Followers: 1)
Journal of Muhammadiyah Medical Laboratory Technologist     Open Access  
Journal of Operating Department Practitioners     Full-text available via subscription   (Followers: 2)
Journal of the American Society of Cytopathology     Hybrid Journal   (Followers: 5)
Journal of Trace Elements in Medicine and Biology     Hybrid Journal   (Followers: 1)
Lab on a Chip     Full-text available via subscription   (Followers: 43)
Laboratory Investigation     Hybrid Journal   (Followers: 3)
Medical Devices & Sensors     Hybrid Journal  
Medical Image Analysis     Hybrid Journal   (Followers: 15)
Medical Instrumentation     Open Access  
Medical Laboratory Observer     Full-text available via subscription  
Medical Laboratory Technology Journal     Open Access  
Medicinal Chemistry Research     Hybrid Journal   (Followers: 12)
Medtech Insight     Full-text available via subscription   (Followers: 4)
Nanomedicine: Nanotechnology, Biology and Medicine     Hybrid Journal   (Followers: 7)
New Zealand Journal of Medical Laboratory Science     Full-text available via subscription   (Followers: 1)
Oriental Pharmacy and Experimental Medicine     Partially Free   (Followers: 3)
Pathology and Laboratory Medicine International     Open Access   (Followers: 7)
Physical Biology     Hybrid Journal   (Followers: 4)
Practical Laboratory Medicine     Open Access   (Followers: 2)
Proceedings of the Institution of Mechanical Engineers Part H: Journal of Engineering in Medicine     Hybrid Journal   (Followers: 3)
Prosthetics and Orthotics International     Hybrid Journal   (Followers: 10)
Pulse     Full-text available via subscription  
Qualitative Research in Medicine & Healthcare     Open Access  
Recent Advances in Biology and Medicine     Open Access  
Regulatory Toxicology and Pharmacology     Hybrid Journal   (Followers: 43)
Reproduction     Full-text available via subscription   (Followers: 7)
Revista Peruana de Medicina Experimental y Salud Pública     Open Access  
Revista Romana de Medicina de Laborator     Open Access  
RSC Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
SA Pharmacist's Assistant     Open Access  
Savannah Journal of Medical Research and Practice     Full-text available via subscription  
SLAS Technology     Hybrid Journal   (Followers: 2)
Statistics in Medicine     Hybrid Journal   (Followers: 192)
Trends in Molecular Medicine     Full-text available via subscription   (Followers: 14)
Turkish Journal of Clinics and Laboratory     Open Access   (Followers: 1)
Similar Journals
Journal Cover
Journal of Experimental and Clinical Medicine
Journal Prestige (SJR): 0.113
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 1309-4483 - ISSN (Online) 1309-5129
Published by Ondokuz Mayıs University Homepage  [5 journals]
  • Investigation of the antimicrobial effects of Sapindus mukorossi on
           endodontic pathogens

    • Authors: İmran SAGLİK ; Öznur GÜÇLÜER TUNCAY , Betil ÖZHAK
      Abstract: Endodontic infections have a polymicrobial nature. Thus, eliminating the microorganisms from infected root canals without damaging healthy surrounding tissue is a major concern. Sapindus mukorossi (S. mukorossi) is a natural product with potential antimicrobial effects. The aim of this study was to evaluate whether various extract solutions of S. mukorossi have an antimicrobial activity against specific endodontic pathogens. Extracts were obtained from S. mukorossi fruit pericarps using methanol, ethanol, butanol and distilled water solvents. The inhibition zone, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and minimum fungicidal concentration (MFC) were determined with disc diffusion assay, broth microdilution assay and agar dilution assay. Antimicrobial inhibitory activity was observed with all four different solvent extracts of S. mukorossi against Fusobacterium nucleatum American Type Culture Collection (ATCC) 25586, Porphyromonas gingivalis ATCC 33277 and Actinomyces odontolyticus (clinical isolate). The MIC values were ranged 10.24-10.24, 0.01-0.64 and 1.28- 2.56 mg/mL, respectively. The MBC value was not detected for Fusobacterium nucleatum ATCC 25586. The MBC values were 0.02-1.25 and 2.56-5.12 mg/ mL for Porphyromonas gingivalis ATCC 33277 and Actinomyces odontolyticus (clinical isolate), respectively. Antifungal activities were also observed with the four different solvent extracts of S. mukorossi against Candida albicans ATCC 10231 and C. albicans clinical isolates 1, 2 and 3. The inhibition zone diameter values were in the range of 18-21 mm. The MIC values for C. albicans ATCC 10231 and C. albicans clinical isolates 1, 2 and 3 were 0.2-0.4 and MFC values were 0.4-0.8 mg/mL, respectively. The antimicrobial effects of the S. mukorossi fruit pericarp extract inhibited the growth of P. gingivalis, A. odontolyticus, F. nucleatum, and especially the C. albicans strains. S. mukorossi extract has interesting potential as an antimicrobial agent against endodontic pathogens.
      PubDate: Fri, 11 Sep 2020 00:00:00 +030
       
  • Association of angiotensin-converting enzyme and nitric oxide synthase
           genes polymorphisms with the risk of myocardial infarction in Bangladesh

    • Authors: Md. Bayejid HOSEN ; Md. Mehedi HASAN , Delowar HOSSAİN , Md. Mostafijur RAHMAN , Jyosna KHANAM , Aklima AKTER , Yearul KABİR , M Zakir Hossain HOWLADER
      Abstract: Myocardial infarction is one of the leading manifestations of illness and death worldwide. The aim of the study was to find out the associations of ACE (I/D) and NOS3 (G894T & 4b/a) genes polymorphisms with the occurrence of myocardial infarction (MI) in Bangladeshi population. The study was conducted on 100 cardiac patients experiencing MI and 150 healthy volunteers with no complications. The genotyping was done using PCR and PCR-RFLP methods and the biochemical parameters were measured using auto biochemistry analyzer. Over all, the serum Troponin I, AST and ALP levels were significantly (p
      PubDate: Fri, 11 Sep 2020 00:00:00 +030
       
  • Effects of leptin on the viability of MCF-7 and T47D cells at different
           glucose concentrations

    • Authors: Pınar DEMİREL ; Soner DOGAN , Ümit ÖZORHAN , Bilge Guvenc TUNA , Todd SCHUSTER , Margot P CLEARY
      Abstract: Obesity is associated with increased risk of breast cancer. Leptin is a well-known factor involved in obesity and its serum levels are increased in breast cancer. Hyperglycemia is another significant risk factor for breast cancer. Consistently, high glucose induces proliferation and invasion of breast cancer cells and in vivo calorie restriction reduces tumorigenesis in rodent models. The aim of this study was to investigate the effect of leptin on the viability and mode of cell death in breast cancer cells incubated in different glucose concentrations to represent caloric restriction. For this purpose, MCF-7 and T47D breast cancer cells incubated in different glucose concentrations for a total of 72 hours were treated with or without leptin either for one hour or 24 hours and the ratio of apoptotic, necrotic and alive cells were analyzed by flow cytometry. Our data revealed that glucose incubation significantly decreased apoptosis and necrosis, while increasing viability in both cell lines in a dose dependent manner. One-hour leptin treatment significantly decreased viability, and increased apoptosis but did not significantly affect necrosis in T47D cells incubated in 2.5 mM glucose. In MCF-7 cells, one-hour leptin incubation significantly increased necrosis but its effects on apoptosis and viability were not significant. In conclusion, glucose induces cell death by apoptosis and necrosis in T47D and MCF-7 cells, respectively in a dose dependent manner. One-hour leptin treatment reverses the effect of low glucose incubation on apoptosis of T47D and necrosis of MCF-7 cells. Moreover, the effect of one-hour leptin treatment on apoptosis or necrosis is significantly higher than that of 24-hour leptin treatment.
      PubDate: Fri, 11 Sep 2020 00:00:00 +030
       
  • Comparison of the protective effects of betamethasone, dexamethasone and
           methylprednisolone in ischemia/reperfusion injury of rat ovary

    • Authors: Ali Doğukan ANĞIN ; Muhammet Ali ORUÇ , Önder SAKİN , Kazibe KOYUNCU , Muzaffer ÇIKMAN , Yasemin ALAN , Kayhan BAŞAK , Asuman ORÇUN , Murat ALAN
      Abstract: AbstractObjectivesOur aim is to evaluate the protective effect of dexamethasone, methylprednisolone and betamethasone treatment against ischemia-reperfusion damage created experimentally in rat ovaries.MethodsFor this study, 30 female Wistar albino rats were used, and the rats were separated randomly into five groups consisting of six rats each: normal ovary, torsion-detorsion, torsion-detorsion + betamethasone 3 mg/kg, torsion-detorsion + dexamethasone 4 mg/kg and torsion-detorsion + metilprednisolone 10 mg/kg. Except for the normal group, an ovarian torsion procedure was implemented in all other groups for 3 hours. Then, a detorsion procedure was implemented to the groups for 3 hours. Medications were given intraperitoneally, 30 minutes before the detorsion procedure. Ovaries of all rats were removed and anti-mullerian hormone (AMH) levels were examined.ResultsThe methylprednisolone treatment seems to be protective for the damage in terms of vascular congestion (p= 0.238), inflammation (p= 0.575), edema (p= 0.118) and cellular degeneration (p= 0.523) by preventing the meaningful increase. The dexamethasone and betamethasone treatment seems to be protective for tissue damage in inflammation (p= 0.575, 0.299), cellular degeneration (p= 0.575, 0.368) and edema (p= 0.212, 0.162). For all steroid groups, preantral+antral follicle decrease and atretic follicle increase was prevented. AMH decline was prevented and levels were similar to normal group (methylprednisolone, betamethasone and dexamethasone p values, respectively;0.872, 0.064, 0.335)ConclusionsIn ischemia / reperfusion injury due to ovarian torsion, steroid use reduces damage and protects ovarian reserves. There was no significant difference between dexamethasone, betamethasone and methylprednisolone in terms of success.
      PubDate: Fri, 11 Sep 2020 00:00:00 +030
       
  • Reactivation of Epstein–Barr virus in Aplastic Anemia: A clinical
           challenge

    • Authors: Nilesh WASEKAR ; Girish BADARKHE , Samadhan PAWAR , Chaitanya BORDE , Yasam Venkata RAMESH , Raj NAGARKAR
      Abstract: Background: Acquired aplastic anemia is an unusual disease associated with pancytopenia characterized by hypocellular bone marrow. Aplastic anemia is an auto-immune disorder wherein patients would show a antithymocyte globulin (ATG)- induced hematological response after T-cell reduction. The combination of cyclosporine A and ATG as immunosuppressive therapy is considered as the standard treatment approach for patients with aplastic anemia. EBV infection in a patient with aplastic anemia is an unusual clinical presentation.Case Report: A 49-year-old Asian female presented to our hospital with dizziness and fatigue. The patient’s platelet count was extremely low. A hypocellular marrow with lymphocytosis was observed with the help of a bone marrow aspirate and biopsy. The patient was given cyclosporine and eltrombopag as a bridge to primary therapy, i.e. antithymocyte globulin (ATG)/allogenic transplant considering she had pancytopenia. The patient developed platelet refractoriness. Epstein-Barr virus polymerase chain reaction (PCR) was performed, considering the patient’s atypical presentation. As per the results, it was significantly positive with 2250 copies/ul. A diagnosis of aplastic anemia with EBV infection was made.
      PubDate: Fri, 11 Sep 2020 00:00:00 +030
       
  • Comparison of Culture, Xpert MTB/RIF and EZN staining method to identify
           Mycobacterium tuberculosis from pulmonary and extra pulmonary specimens

    • Authors: Yeliz TANRIVERDİ ÇAYCI; İlknur BIYIK , Asuman BIRINCI
      Abstract: Mycobacterium tuberculosis is a major health problem worldwide, especially in developing countries. The effective treatment of M. tuberculosis depends on early diagnosis. In this study, 1577 M. tuberculosis strains were evaluated retrospectively from clinical samples sent between March 2014 and June 2018. The rate of pulmonary samples was determined as 694 (44%). Positive sample rate was 74 (4.69%) in culture, 19 (1.20%) in EZN staining and 75 (4.75%) in Xpert MTB/RIF. Compared to standard culture, the sensitivity, specificity, positive and negative predictive values of the Xpert MTB / RIF system were 100%, 99.93%, 98.66% and 100%, respectively; The sensitivity, specificity, positive and negative predictive values of EZN were 57.36%, 100%, 100% and 96.46%, respectively. Early diagnosis and treatment of M. tuberculosis is of great importance. According to these results, it can be concluded that Xpert MTB / RIF is a fast and reliable system that can be used in the diagnosis of tuberculosis and when used together with conventional tests, it can make important contributions to the diagnosis of tuberculosis.
      PubDate: Fri, 11 Sep 2020 00:00:00 +030
       
 
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