JournalTOCs

Drug Design, Development and Therapy
Journal Prestige (SJR): 0.974

Citation Impact (citeScore): 3
Number of Followers: 4

This is an Open Access Journal

Open Access journal
ISSN (Print) 1177-8881
Published by Dove Medical Press

[135 journals]

LC-MS/MS Estimation of the Anti-Cancer Agent Tandutinib Levels in Human
Liver Microsomes: Metabolic Stability Evaluation Assay
- PubDate: Fri, 23 Oct 2020 12:01:00 +130
  DOI: 10.2147/DDDT.S274118
Co-Delivery Anticancer Drug Nanoparticles for Synergistic Therapy Against
Lung Cancer Cells
- PubDate: Fri, 23 Oct 2020 12:01:00 +130
  DOI: 10.2147/DDDT.S275123
Pharmacokinetic/Pharmacodynamic Interaction Between Evogliptin and
Pioglitazone in Healthy Male Subjects
- PubDate: Fri, 23 Oct 2020 12:01:00 +130
  DOI: 10.2147/DDDT.S275336
Synthesis, Cytotoxic Analysis, and Molecular Docking Studies of Tetrazole
Derivatives via N-Mannich Base Condensation as Potential Antimicrobials
- PubDate: Fri, 23 Oct 2020 12:00:00 +130
  DOI: 10.2147/DDDT.S270896
Enhancement of Pancreatic Cancer Therapy Efficacy by Type-1 Matrix
Metalloproteinase-Functionalized Nanoparticles for the Selective Delivery
of Gemcitabine and Erlotinib
- PubDate: Fri, 23 Oct 2020 12:00:00 +130
  DOI: 10.2147/DDDT.S270303
Resveratrol Protects Osteoblasts Against Dexamethasone-Induced
Cytotoxicity Through Activation of AMP-Activated Protein Kinase
- PubDate: Fri, 23 Oct 2020 11:59:00 +130
  DOI: 10.2147/DDDT.S266502
Alprostadil Injection Attenuates Coronary Microembolization-Induced
Myocardial Injury Through GSK-3β/Nrf2/HO-1 Signaling-Mediated
Apoptosis Inhibition
- PubDate: Thu, 22 Oct 2020 09:01:00 +130
  DOI: 10.2147/DDDT.S272877
Metabolic Activation and Covalent Protein Binding of Berberrubine: Insight
into the Underlying Mechanism Related to Its Hepatotoxicity
- PubDate: Thu, 22 Oct 2020 09:01:00 +130
  DOI: 10.2147/DDDT.S274627
Enteric-Coated Strategies in Colorectal Cancer Nanoparticle Drug Delivery
System
- PubDate: Wed, 21 Oct 2020 09:51:00 +130
  DOI: 10.2147/DDDT.S273612
ISL Induces Apoptosis and Autophagy in Hepatocellular Carcinoma via
Downregulation of PI3K/AKT/mTOR Pathway in vivo and in vitro
- PubDate: Tue, 20 Oct 2020 09:36:00 +130
  DOI: 10.2147/DDDT.S270124
Validated Microwell-Based Spectrofluorimetric Method for Quantification of
Ravidasvir (New Anti-Chronic Hepatitis C Virus-GT4) in Rat Plasma and Its
Application to Pharmacokinetic Study
- PubDate: Tue, 20 Oct 2020 09:31:00 +130
  DOI: 10.2147/DDDT.S237949
Development, Characterization, and in-vivo Pharmacokinetic Study of
Lamotrigine Solid Self-Nanoemulsifying Drug Delivery System
- PubDate: Mon, 19 Oct 2020 13:22:00 +130
  DOI: 10.2147/DDDT.S263898
Simvastatin-Nicotinamide Co-Crystals: Formation, Pharmaceutical
Characterization and in vivo Profile
- PubDate: Mon, 19 Oct 2020 07:57:00 +130
  DOI: 10.2147/DDDT.S270742
Proteasome, a Promising Therapeutic Target for Multiple Diseases Beyond
Cancer
- PubDate: Mon, 19 Oct 2020 07:56:00 +130
  DOI: 10.2147/DDDT.S265793
Synthesis and Identification of a Novel Peptide, Ac-SDK (Biotin) Proline,
That Can Elicit Anti-Fibrosis Effects in Rats Suffering from Silicosis
- PubDate: Mon, 19 Oct 2020 07:55:00 +130
  DOI: 10.2147/DDDT.S262716
Bucco-Adhesive Film as a Pediatric Proper Dosage Form for Systemic
Delivery of Propranolol Hydrochloride: In-vitro and in-vivo Evaluation
- PubDate: Thu, 15 Oct 2020 14:50:00 +130
  DOI: 10.2147/DDDT.S267317
HLJ2 Effectively Ameliorates Colitis-Associated Cancer via Inhibition of
NF-κB and Epithelial–Mesenchymal Transition
- PubDate: Thu, 15 Oct 2020 14:48:00 +130
  DOI: 10.2147/DDDT.S262806
Effects of Anisodine Hydrobromide on the Cardiovascular and Respiratory
Functions in Conscious Dogs
- PubDate: Tue, 13 Oct 2020 10:40:00 +130
  DOI: 10.2147/DDDT.S268113
EGCG Upregulates UCP3 Levels to Protect MIN6 Pancreatic Islet Cells from
Interleukin-1β-Induced Apoptosis
- PubDate: Tue, 13 Oct 2020 10:00:00 +130
  DOI: 10.2147/DDDT.S270345
Clinical Outcome of Systemic Treatment for Advanced Soft Tissue Sarcoma:
Real-Life Perspective in Japan
- PubDate: Mon, 12 Oct 2020 09:43:00 +130
  DOI: 10.2147/DDDT.S275526
Dexmedetomidine Attenuates Cellular Injury and Apoptosis in H9c2
Cardiomyocytes by Regulating p-38MAPK and Endoplasmic Reticulum Stress
- PubDate: Mon, 12 Oct 2020 09:41:00 +130
  DOI: 10.2147/DDDT.S265970
The Potential Roles of Epigallocatechin-3-Gallate in the Treatment of
Ovarian Cancer: Current State of Knowledge
- PubDate: Mon, 12 Oct 2020 09:40:00 +130
  DOI: 10.2147/DDDT.S253092
Effect of Platelet-Activating Factor on Barrier Function of ARPE-19 Cells
- PubDate: Mon, 12 Oct 2020 09:40:00 +130
  DOI: 10.2147/DDDT.S251941
Pharmacokinetics and Bioequivalence of Two Formulations of Valsartan 80 mg
Capsules: A Randomized, Single Dose, 4-Period Crossover Study in Healthy
Chinese Volunteers Under Fasting and Fed Conditions
- PubDate: Mon, 12 Oct 2020 09:40:00 +130
  DOI: 10.2147/DDDT.S253078
Pristimerin Inhibits Osteoclast Differentiation and Bone Resorption in
vitro and Prevents Ovariectomy-Induced Bone Loss in vivo
- PubDate: Fri, 09 Oct 2020 12:56:00 +130
  DOI: 10.2147/DDDT.S275128
Physical Compatibility and Chemical Stability of Fentanyl and Naloxone
Hydrochloride in 0.9% Sodium Chloride Injection Solution for
Patient-Controlled Analgesia Administration
- PubDate: Fri, 09 Oct 2020 12:49:00 +130
  DOI: 10.2147/DDDT.S248209
Wogonin Ameliorates Renal Inflammation and Fibrosis by Inhibiting
NF-κB and TGF-β1/Smad3 Signaling Pathways in Diabetic
Nephropathy
- PubDate: Thu, 08 Oct 2020 11:56:00 +130
  DOI: 10.2147/DDDT.S274256
The Impact of Icariside II on Human Prostate Cancer Cell Proliferation,
Mobility, and Autophagy via PI3K-AKT-mTOR Signaling Pathway
- PubDate: Thu, 08 Oct 2020 11:55:00 +130
  DOI: 10.2147/DDDT.S268524
Novel Molecular Mechanism of Aspirin and Celecoxib Targeting Mammalian
Neuraminidase-1 Impedes Epidermal Growth Factor Receptor Signaling Axis
and Induces Apoptosis in Pancreatic Cancer Cells
- PubDate: Thu, 08 Oct 2020 11:54:00 +130
  DOI: 10.2147/DDDT.S264122
Cordycepin Alleviates Anterior Cruciate Ligament Transection
(ACLT)-Induced Knee Osteoarthritis Through Regulating TGF-β Activity
and Autophagy [Retraction]
- PubDate: Wed, 07 Oct 2020 11:34:00 +130
  DOI: 10.2147/DDDT.S283594