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Skin Appendage Disorders
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ISSN (Print) 2296-9195 - ISSN (Online) 2296-9160
Published by Karger

[120 journals]

How to Optimize Trichoscopy for Evaluation of Scalp Vessels
- Abstract: Introduction: Trichoscopy greatly facilitates clinical diagnosis in patients with hair loss and may decrease the necessity for histopathological examination. Structures which may be revealed by trichoscopy include hair shafts, hair follicle openings, the perifollicular epidermis, and cutaneous microvessels. Cutaneous microvessels revealed in trichoscopy may vary in type and number depending on the scalp area, type of the disease, and its activity. Firm direct pressure (diascopy) might result in their blanching, but as of yet, there are no studies on the types of vessels that do or do not blanch on applying pressure. Methods: We studied interfollicular twisted loops in 16 cases of biopsy-confirmed scalp psoriasis and 37 cases of arborizing vessels in normal subjects and seborrheic dermatitis patients. Results: We observed that all arborizing red line vessels blanched on applying pressure. Instead, the vast majority of twisted and simple loops, despite their vascular nature, did not blanch on performing diascopy. Conclusion: In the light of these findings, diascopy of vascular changes in hair loss patients might provide additional clues for a proper diagnosis, especially in differentiating scalp psoriasis, seborrheic dermatitis, and discoid lupus erythematosus.
  Skin Appendage Disord
  PubDate: Mon, 25 May 2020 13:45:28 +020
Alopecia Areata and Toxic Metals
- Abstract: Toxic metals are not so rare but are often neglected causes of alopecia areata in men and women. Thallium, arsenic, selenium, and mercury are the most common cause of metals-related alopecia, which is what Vicky Yu and colleagues’ found. Other than the presence of thallium, arsenic, mercury, and selenium, cadmium, bismuth, lithium, and copper should also be taken into account when dermatologists are considering toxic metals as a potential cause of alopecia areata in humans.
  Skin Appendage Disord
  PubDate: Sat, 16 May 2020 13:56:18 +020
Hidradenitis Suppurativa: Surgical and Postsurgical Management
- Abstract: Background: Hidradenitis suppurativa (HS) is a chronic inflammatory disorder. Several medical treatments, with varying degrees of efficacy, have been developed. However, in most cases of advanced HS, the definitive treatment option is often represented by surgical excisions. Objective: Surgical techniques, reconstructive approach, and local wound care should be accurately designed in order to obtain the best result. In this review we analyze the possible surgical treatments and local wound care. Methods: A MEDLINE search was performed on the various surgical treatments, reconstructive techniques, and local wound care. Results: Surgical treatment is a common therapeutic modality for HS. Different surgical reconstructive techniques and post-surgical wound care approaches are described for the management of HS patients. Conclusions: There were few high-quality evidence-based studies evaluating the surgical management of HS. Many disparate HS severity scores were used in these studies, making comparisons between them difficult. Nonetheless, research on different surgical approaches and wound care management has increased substantially in the past decade and it has given patients more surgical therapeutic strategies. The description of the best combinations and timing of surgery, wound care, and medical therapies will be a matter of future research for the definition of the optimal management of the HS patient.
  Skin Appendage Disord
  PubDate: Thu, 14 May 2020 12:12:40 +020
Publisher's Note
- Abstract:
  Skin Appendage Disord
  PubDate: Tue, 12 May 2020 13:35:57 +020
Creatine Phosphokinase Values during Low Starting Dose Isotretinoin
Therapy
- Abstract: Background: The value of creatine phosphokinase (CPK) monitoring during isotretinoin therapy is still a matter of debate because of the rarity of muscular and kidney damage in this setting. The aim of the study was to investigate the incidence of CPK elevation during a low starting dose isotretinoin regimen and to discuss the clinical approach to patients with increased CPK. Methods: We reviewed the records of the acne patients from 2015 to 2018 at the University of Ferrara and at the University of Modena and Reggio Emilia. Routine clinical and laboratory follow-up was analyzed. Results: The records of 328 patients were included in the study. Abnormal CPK levels were observed in 5.5% of cases. Revised Leeds acne scores and visual assessment scale (VAS) measurements decreased significantly after isotretinoin therapy. Discussion: The adoption of the low starting dose isotretinoin regimen is associated with low incidence of CPK elevation. The finding of CPK over the conventional value of 5 times above the limit was rarely observed and was never associated with kidney damage. Therefore, it should be interpreted as a relatively benign phenomenon that does not require the interruption of isotretinoin therapy and that should be managed mainly through the reassurance of the patient.
  Skin Appendage Disord
  PubDate: Tue, 05 May 2020 09:57:11 +020
Small Molecules and Biologics in the Treatment of Nail Psoriasis
- Abstract: Nail psoriasis (PsO) is a disorder with profound impact on patients’ quality of life. Several challenges and unmet needs remain in the treatment of nail PsO. Introduction of biologics and small molecules in the treatment of nail PsO has allowed for rapid control of the disease and high efficacy. The aim of this review was to present the published studies on nail PsO therapy with biologics and small molecules and illuminate the results in the studies where the design and outcome evaluation had nail PsO in the forefront.
  Skin Appendage Disord
  PubDate: Thu, 30 Apr 2020 14:42:21 +020
Public Perception of Management of Hair Conditions in America: Results
from a National Survey
- Abstract:
  Skin Appendage Disord
  PubDate: Wed, 15 Apr 2020 10:02:44 +020
Isolated Eyebrow Alopecia: When the Dermoscope Makes the Diagnosis
- Abstract:
  Skin Appendage Disord
  PubDate: Tue, 14 Apr 2020 08:45:33 +020
Erythematous Papules Involving the Eyebrows in a Patient with a History of
Rosacea and Hair Loss
- Abstract:
  Skin Appendage Disord
  PubDate: Wed, 01 Apr 2020 13:58:07 +020
Finasteride in Frontal Fibrosing Alopecia: Joining the Dots!
- Abstract:
  Skin Appendage Disord
  PubDate: Mon, 30 Mar 2020 08:46:04 +020