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OBSTETRICS AND GYNECOLOGY (207 journals)                  1 2 | Last

Showing 1 - 200 of 207 Journals sorted alphabetically
Acta Obstétrica e Ginecológica Portuguesa     Open Access   (Followers: 1)
Acta Obstetricia et Gynecologica Scandinavica     Hybrid Journal   (Followers: 16)
Advances in Neonatal Care     Hybrid Journal   (Followers: 47)
Advances in Reproductive Sciences     Open Access   (Followers: 2)
Advances in Sexual Medicine     Open Access   (Followers: 7)
African Journal for Infertility and Assisted Conception     Open Access   (Followers: 1)
African Journal of Midwifery and Women's Health     Full-text available via subscription   (Followers: 13)
African Journal of Reproductive Health     Open Access   (Followers: 8)
Aktuální Gynekologie a Porodnictví     Open Access   (Followers: 1)
American Journal of Obstetrics & Gynecology MFM     Hybrid Journal   (Followers: 2)
American Journal of Obstetrics and Gynecology     Hybrid Journal   (Followers: 276)
American Journal of Perinatology     Hybrid Journal   (Followers: 39)
American Journal of Perinatology Reports     Open Access   (Followers: 18)
American Journal of Reproductive Immunology     Hybrid Journal   (Followers: 6)
Andrology & Gynecology : Current Research     Hybrid Journal   (Followers: 4)
Archives of Gynecology and Obstetrics     Hybrid Journal   (Followers: 19)
Asian Pacific Journal of Reproduction     Open Access  
Australian and New Zealand Journal of Obstetrics and Gynaecology     Hybrid Journal   (Followers: 52)
Best Practice & Research Clinical Obstetrics & Gynaecology     Hybrid Journal   (Followers: 34)
Biology of Reproduction     Full-text available via subscription   (Followers: 11)
Birth     Hybrid Journal   (Followers: 40)
Birth Defects Research Part B: Developmental and Reproductive Toxicology     Hybrid Journal   (Followers: 8)
BJOG : An International Journal of Obstetrics and Gynaecology     Partially Free   (Followers: 299)
British Journal of Midwifery     Full-text available via subscription   (Followers: 91)
Case Reports in Obstetrics and Gynecology     Open Access   (Followers: 11)
Case Reports in Perinatal Medicine     Hybrid Journal   (Followers: 11)
Clínica e Investigación en Ginecología y Obstetricia     Full-text available via subscription  
Clinical Lactation     Open Access   (Followers: 22)
Clinical Medicine Insights : Reproductive Health     Open Access   (Followers: 2)
Clinical Medicine Insights : Women's Health     Open Access   (Followers: 4)
Clinical Obstetrics & Gynecology     Full-text available via subscription   (Followers: 27)
Clinics in Perinatology     Full-text available via subscription   (Followers: 25)
Contemporary OB GYN - Obstetrics-Gynecology & Women's Health     Full-text available via subscription   (Followers: 6)
Contraception     Hybrid Journal   (Followers: 20)
Contraception : X     Open Access   (Followers: 1)
Contraception and Reproductive Medicine     Open Access   (Followers: 2)
Current Obstetrics and Gynecology Reports     Hybrid Journal   (Followers: 4)
Current Opinion in Obstetrics & Gynecology     Hybrid Journal   (Followers: 13)
Current Women's Health Reviews     Hybrid Journal   (Followers: 5)
Early Human Development     Hybrid Journal   (Followers: 13)
Ecography     Hybrid Journal   (Followers: 27)
EMC - Ginecología-Obstetricia     Full-text available via subscription   (Followers: 1)
European Clinics in Obstetrics and Gynaecology     Hybrid Journal   (Followers: 5)
European Journal of Contraception & Reproductive Health Care     Hybrid Journal   (Followers: 5)
European Journal of Obstetrics & Gynecology and Reproductive Biology     Hybrid Journal   (Followers: 29)
European Journal of Obstetrics & Gynecology and Reproductive Biology : X     Open Access  
Expert Review of Obstetrics & Gynecology     Hybrid Journal   (Followers: 5)
Fertility and Sterility     Full-text available via subscription   (Followers: 79)
Fertility Research and Practice     Open Access   (Followers: 2)
Fertility Science and Research     Open Access  
Fetal and Maternal Medicine Review     Hybrid Journal   (Followers: 6)
Fetal Diagnosis and Therapy     Full-text available via subscription   (Followers: 10)
Ginekologia i Perinatologia Praktyczna     Hybrid Journal  
Ginekologia Polska     Open Access  
Global Reproductive Health     Open Access  
gynäkologie + geburtshilfe     Full-text available via subscription   (Followers: 2)
Gynäkologisch-geburtshilfliche Rundschau     Full-text available via subscription   (Followers: 1)
Gynakologische Endokrinologie     Hybrid Journal  
Gynecologic and Obstetric Investigation     Full-text available via subscription   (Followers: 5)
Gynecologic Oncology     Hybrid Journal   (Followers: 28)
Gynecologic Oncology Reports     Open Access   (Followers: 11)
Gynecologic Oncology Research and Practice     Open Access   (Followers: 1)
Gynecological Endocrinology     Hybrid Journal   (Followers: 6)
Gynecological Surgery     Open Access   (Followers: 4)
Gynécologie Obstétrique & Fertilité     Full-text available via subscription   (Followers: 1)
Gynécologie Obstétrique Fertilité & Sénologie     Hybrid Journal   (Followers: 1)
Gynecology     Open Access  
Gynecology and Minimally Invasive Therapy     Open Access  
Gynecology Obstetrics & Reproductive Medicine     Open Access   (Followers: 1)
Health Care For Women International     Hybrid Journal   (Followers: 8)
Human Reproduction     Hybrid Journal   (Followers: 77)
Human Reproduction Open     Open Access   (Followers: 1)
Human Reproduction Update     Hybrid Journal   (Followers: 19)
Hypertension in Pregnancy     Hybrid Journal   (Followers: 9)
Indian Journal of Gynecologic Oncology     Hybrid Journal  
Indonesian Journal of Obstetrics and Gynecology     Open Access  
Infectious Diseases in Obstetrics and Gynecology     Open Access   (Followers: 5)
International Journal of Anatomical Variations     Open Access  
International Journal of Childbirth     Hybrid Journal   (Followers: 8)
International Journal of Gynecological Cancer     Hybrid Journal   (Followers: 24)
International Journal of Gynecological Pathology     Hybrid Journal   (Followers: 9)
International Journal of Gynecology & Obstetrics     Hybrid Journal   (Followers: 26)
International Journal of Neonatal Screening     Open Access   (Followers: 3)
International Journal of Obstetric Anesthesia     Full-text available via subscription   (Followers: 14)
International Journal of Obstetrics, Perinatal and Neonatal Nursing     Full-text available via subscription  
International Journal of Reproduction, Contraception, Obstetrics and Gynecology     Open Access   (Followers: 14)
International Journal of Reproductive Medicine     Open Access   (Followers: 5)
International Urogynecology Journal     Hybrid Journal   (Followers: 4)
Italian Journal of Anatomy and Embryology     Open Access   (Followers: 1)
Journal de Gynécologie Obstétrique et Biologie de la Reproduction     Full-text available via subscription  
Journal für Gynäkologische Endokrinologie / Schweiz     Hybrid Journal  
Journal für Gynäkologische Endokrinologie/Österreich     Hybrid Journal  
Journal of Assisted Reproduction and Genetics     Hybrid Journal   (Followers: 6)
Journal of Basic and Clinical Reproductive Sciences     Open Access   (Followers: 1)
Journal of Breast Health     Open Access  
Journal of Clinical Gynecology and Obstetrics     Open Access   (Followers: 7)
Journal of Endometriosis and Pelvic Pain Disorders     Hybrid Journal  
Journal of Evidence-based Care     Open Access   (Followers: 8)
Journal of Family Planning and Reproductive Health Care     Hybrid Journal   (Followers: 12)
Journal of Genital System & Disorders     Hybrid Journal   (Followers: 3)
Journal of Gynecologic Surgery     Hybrid Journal   (Followers: 1)
Journal of Gynecological Research and Obstetrics     Open Access   (Followers: 1)
Journal of Gynecology Obstetrics and Human Reproduction     Hybrid Journal  
Journal of Human Lactation     Hybrid Journal   (Followers: 30)
Journal of Human Reproductive Sciences (JHRS)     Open Access   (Followers: 3)
Journal of Lower Genital Tract Disease     Hybrid Journal  
Journal of Maternal and Child Health     Open Access  
Journal of Maternal-Fetal & Neonatal Medicine     Hybrid Journal   (Followers: 40)
Journal of Midwifery     Open Access   (Followers: 3)
Journal of Midwifery & Women's Health     Hybrid Journal   (Followers: 66)
Journal of Midwifery and Reproduction     Open Access   (Followers: 5)
Journal of Midwifery and Reproductive Health     Open Access   (Followers: 15)
Journal of Minimally Invasive Gynecology     Full-text available via subscription   (Followers: 12)
Journal of Neonatal-Perinatal Medicine     Hybrid Journal   (Followers: 14)
Journal of Obstetric Anaesthesia and Critical Care     Open Access   (Followers: 22)
Journal of Obstetric, Gynecologic, & Neonatal Nursing     Hybrid Journal   (Followers: 36)
Journal of Obstetrics and Gynaecology     Hybrid Journal   (Followers: 34)
Journal of Obstetrics and Gynaecology Canada     Hybrid Journal   (Followers: 1)
Journal of Obstetrics and Gynaecology Research     Hybrid Journal   (Followers: 9)
Journal of Obstetrics and Gynecology of India     Hybrid Journal   (Followers: 4)
Journal of Obstetrics and Women's Diseases     Open Access  
Journal of Pediatric and Adolescent Gynecology     Full-text available via subscription   (Followers: 3)
Journal of Perinatal Education     Hybrid Journal   (Followers: 5)
Journal of Perinatal Medicine     Hybrid Journal   (Followers: 12)
Journal of Perinatology     Hybrid Journal   (Followers: 7)
Journal of Psychosomatic Obstetrics & Gynecology     Hybrid Journal   (Followers: 3)
Journal of Reproduction and Contraception     Full-text available via subscription   (Followers: 4)
Journal of Reproductive and Infant Psychology     Hybrid Journal   (Followers: 24)
Journal of Reproductive Biotechnology and Fertility     Open Access   (Followers: 2)
Journal of Reproductive Health and Medicine     Full-text available via subscription   (Followers: 2)
Journal of Reproductive Immunology     Hybrid Journal   (Followers: 2)
Jurnal Kebidanan Midwiferia     Open Access  
Jurnal Ners     Open Access  
La Revue Sage-Femme     Full-text available via subscription  
Majalah Obstetri & Ginekologi     Open Access  
Maternal Health, Neonatology and Perinatology     Open Access   (Followers: 9)
Menopause     Hybrid Journal   (Followers: 14)
Menopause International     Hybrid Journal   (Followers: 9)
MHR: Basic science of reproductive medicine     Hybrid Journal   (Followers: 1)
Middle East Fertility Society Journal     Open Access   (Followers: 3)
Midwifery     Hybrid Journal   (Followers: 74)
Midwifery Today     Full-text available via subscription   (Followers: 16)
Nascer e Crescer : Birth and Growth Medical Journal     Open Access  
Neonatal Network - Journal of Neonatal Nursing     Hybrid Journal   (Followers: 25)
Neonatology     Full-text available via subscription   (Followers: 48)
Nepal Journal of Obstetrics and Gynaecology     Open Access   (Followers: 2)
OA Women's Health     Open Access   (Followers: 1)
Obstetric Anesthesia Digest     Full-text available via subscription   (Followers: 1)
Obstetric Medicine     Hybrid Journal   (Followers: 8)
Obstetrical & Gynecological Survey     Hybrid Journal   (Followers: 14)
Obstetrics & Gynecology     Partially Free   (Followers: 93)
Obstetrics and Gynaecology Forum     Full-text available via subscription   (Followers: 1)
Obstetrics and Gynecology Clinics of North America     Full-text available via subscription   (Followers: 21)
Obstetrics and Gynecology International     Open Access   (Followers: 7)
Obstetrics, Gynaecology & Reproductive Medicine     Full-text available via subscription   (Followers: 17)
Open Journal of Obstetrics and Gynecology     Open Access   (Followers: 5)
Paediatric and Perinatal Epidemiology     Hybrid Journal   (Followers: 9)
Perinatología y Reproducción Humana     Open Access   (Followers: 1)
Perspectives On Sexual and Reproductive Health     Hybrid Journal   (Followers: 7)
Placenta     Hybrid Journal   (Followers: 2)
Postgraduate Obstetrics & Gynecology     Full-text available via subscription   (Followers: 1)
Proceedings in Obstetrics and Gynecology     Open Access   (Followers: 4)
Progresos de Obstetricia y Ginecología     Full-text available via subscription   (Followers: 1)
Reprodução & Climatério     Open Access   (Followers: 1)
Reproduction     Full-text available via subscription   (Followers: 7)
Reproduction Fertility and Development     Hybrid Journal   (Followers: 5)
Reproductive Biology and Endocrinology     Open Access   (Followers: 4)
Reproductive BioMedicine Online     Full-text available via subscription   (Followers: 8)
Reproductive Endocrinology     Open Access   (Followers: 3)
Reproductive Health     Open Access   (Followers: 2)
Reproductive Health Matters     Open Access   (Followers: 5)
Reproductive Medicine and Biology     Open Access   (Followers: 3)
Reproductive Sciences     Hybrid Journal   (Followers: 1)
Research and Reports in Neonatology     Open Access   (Followers: 5)
Research in Obstetrics and Gynecology     Open Access   (Followers: 2)
Research Journal of Obstetrics and Gynecology     Open Access   (Followers: 5)
Revista Brasileira de Ginecologia e Obstetrícia / RBGO Gynecology and Obstetrics     Open Access  
Revista Chilena de Obstetricia y Ginecologia     Open Access   (Followers: 1)
Revista Cubana de Obstetricia y Ginecología     Open Access  
Revista Internacional de Andrología     Full-text available via subscription  
Revista Peruana de Ginecología y Obstetricia     Open Access  
Revue de médecine périnatale     Hybrid Journal   (Followers: 1)
Scientific Journal of Hamadan Nursing & Midwifery Faculty     Open Access   (Followers: 1)
Seksuologia Polska     Full-text available via subscription  
Seminars in Breast Disease     Hybrid Journal   (Followers: 1)
Seminars in Perinatology     Hybrid Journal   (Followers: 21)
Seminars in Reproductive Medicine     Hybrid Journal  
Sexes     Open Access  
Siklus : Journal Research Midwifery Politeknik Tegal     Open Access   (Followers: 2)
South African Journal of Obstetrics and Gynaecology     Open Access   (Followers: 2)
Southern African Journal of Gynaecological Oncology     Open Access   (Followers: 1)
Sri Lanka Journal of Obstetrics and Gynaecology     Open Access   (Followers: 1)
Systems Biology in Reproductive Medicine     Hybrid Journal  
Taiwanese Journal of Obstetrics and Gynecology     Open Access   (Followers: 1)
Teratology Studies     Open Access  
Thai Journal of Obstetrics and Gynaecology     Open Access  
The Obstetrician & Gynaecologist     Hybrid Journal   (Followers: 7)
The Practising Midwife     Full-text available via subscription   (Followers: 8)
Trends in Urology Gynaecology & Sexual Health     Hybrid Journal   (Followers: 2)
Tropical Journal of Obstetrics and Gynaecology     Open Access   (Followers: 2)

        1 2 | Last

Similar Journals
Journal Cover
Journal of Human Reproductive Sciences (JHRS)
Journal Prestige (SJR): 0.585
Citation Impact (citeScore): 1
Number of Followers: 3  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0974-1208
Published by Medknow Publishers Homepage  [425 journals]
  • From the editor's desk

    • Authors: Madhuri Patil
      Pages: 271 - 273
      Abstract: Madhuri Patil
      Journal of Human Reproductive Sciences 2019 12(4):271-273

      Citation: Journal of Human Reproductive Sciences 2019 12(4):271-273
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_165_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Female unexplained infertility: A disease with imbalanced adaptive
           immunity

    • Authors: Motahareh Ehsani, Mousa Mohammadnia-Afrouzi, Mohammad Mirzakhani, Sedighe Esmaeilzadeh, Mehdi Shahbazi
      Pages: 274 - 282
      Abstract: Motahareh Ehsani, Mousa Mohammadnia-Afrouzi, Mohammad Mirzakhani, Sedighe Esmaeilzadeh, Mehdi Shahbazi
      Journal of Human Reproductive Sciences 2019 12(4):274-282
      Unexplained infertility (UI) among women consists of only 10-17% of infertile females. Unexplained or idiopathic infertility is a condition, in which couples are not able to conceive without any definite causes. The presence of the decidual immune system (innate or adaptive) is essential for a successful pregnancy and fertility that is mediated by T helper (Th) 1, Th2, Th17, T follicular helper, CD8+ CD28− T, and regulatory T cells, as well as autoantibodies such as antiphospholipid antibody, antithyroid antibody, antiovarian antibody, cytokines, and chemokines. Therefore, altered proportions or levels of the mentioned compartments of the adaptive immune system may cause pregnancy failure and infertility, especially in UI. Consequently, a deep understanding of immunological compartments in females with UI may help us to define the causes of this disease with regard to immunology. This review will discuss immunological factors, including cellular, molecular components, and transcription factors that are involved in the etiology of UI.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):274-282
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_30_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • T-shaped uterus in the 21st century (Post DES era) – We need
           to know more!

    • Authors: Akanksha Sood, Muhammad Akhtar
      Pages: 283 - 286
      Abstract: Akanksha Sood, Muhammad Akhtar
      Journal of Human Reproductive Sciences 2019 12(4):283-286
      T-Shaped uterus is a rare uterine malformation, and has classically been associated with “in-utero” exposure of DES (diethylstilbestrol). Surprisingly, the prevalence of T shaped uterus is significant even today. Hysteroscopic metroplasty is a simple procedure which can potentially improve outcomes in sub-fertile women, but the data is not robust. There is a need for centralised database for registration of women with T shaped uterine anomalies, which will help in defining clear diagnostic criteria, surgical indication & technique, and follow up of reproductive outcomes after the procedure.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):283-286
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_101_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Causes and prevalence of factors causing infertility in a public health
           facility

    • Authors: Priyanka Sanjay Deshpande, Alka ShantiPrakash Gupta
      Pages: 287 - 293
      Abstract: Priyanka Sanjay Deshpande, Alka ShantiPrakash Gupta
      Journal of Human Reproductive Sciences 2019 12(4):287-293
      Background: Infertility causes change according to local demographics. There is thus the need to find the causes of infertility in context to local population to aid and direct management strategies accordingly. Aims: The aims were to study the causes of infertility and to calculate the proportion of the individual factors contributing to it in the population coming to a tertiary level public health facility. Setting and Design: This cross-sectional, observational study was done in an infertility clinic in a medical college and government hospital. Materials and Methods: The study comprised 120 couples who came for infertility evaluation and treatment. Cause of infertility in the couple was assigned on the basis of history and examination findings. The prevalence of each cause was evaluated. Statistical Analysis: Results were tabulated, and the prevalence of individual factors was calculated. Intratable analysis was done using SPSS 16.0. Results: Primary infertility (57.5%) was more prevalent than secondary infertility (42.5%). Female factor accounted for 46.6% of the cases with polycystic ovarian syndrome (PCOS) being the leading cause (46%). Infertility was seen equally in lean and obese PCOS cases. Infectious causes such as pelvic inflammatory disease and tuberculosis were significantly associated with tubal factor infertility (P = 0.001). Infertility causes changed as the age of marriage increased. In couples married for less than 5 years, PCOS was the main cause whereas later,male factor and unexplained infertility were the most common causes seen. Male factor contributed to 20% of the cases of infertility, and both tobacco and alcohol consumption were significantly associated with abnormal semen reports (P = 0.001). Conclusion: Causes of infertility vary according to the age of the couples and age of marriage. Although PCOS remains the main cause, infections are a major cause of tubal factor infertility, and tobacco and alcohol worsen the male factor. One-third of the cases still remain unexplained.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):287-293
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_140_18
      Issue No: Vol. 12, No. 4 (2019)
       
  • The effect of suboptimal semen parameters on male partner's ability to
           conceive. Is he really subfertile because the test says so?

    • Authors: Rubina Izhar, Zubaida Masood, Samia Husain, Suhaima Tahir, Mataa-E- Masood
      Pages: 294 - 298
      Abstract: Rubina Izhar, Zubaida Masood, Samia Husain, Suhaima Tahir, Mataa-E- Masood
      Journal of Human Reproductive Sciences 2019 12(4):294-298
      Context: In many developing countries, subfertility treatment is not covered by government-funded institutions. It is observed that healthcare providers incriminate male factor for subfertility even when only a slight deviation from presumed normal criteria is observed. Aim: This study aims to provide scientific evidence that pregnancies are possible at semen parameters that are below the generally accepted lower limits of normal. Setting and Design: This was a retrospective cohort study conducted from January 2014 to December 2018. Materials and Methods: During the study period, couples who conceived without any treatment of male partner were included. The World Health Organization (WHO) reference values for semen analysis were utilized to assess the reports. The primary outcome measure was conception despite abnormal semen parameters. Statistical Analysis Used: Data were analyzed using the SPSS software program, version 15.0 (IBM, Armonk, USA). Results: Of the 332 couples included, 233 (70.1%) couples conceived despite suboptimal semen parameters, The most common criterion not satisfied was rapid linear motility –200 (85.8%), 87 (37.3%) men were oligozoospermic, 94 (40.3%) were asthenozoospermic, and 21 (9%) were teratozoospermic. The abnormalities were more common in men having primary subfertility (71.7% vs. 28.3%, P = 0.002). The abnormalities were most common in the age group 40–44 years (n = 91, 39.1%) and those who were overweight (n = 110, 47%). Conclusions: A consensus for defining poor semen criteria is the need of the hour so that these males can be counseled satisfactorily. WHO criteria are a standard commonly employed, but they do not necessarily predict the fertility potential.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):294-298
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_29_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • There is no association between premature ovarian insufficiency and levels
           of fetuin-A/α2-Heremans-Schmid glycoprotein

    • Authors: A Seval Ozgu-Erdinc, Zeynep Asli Oskovi Kaplan, Yaprak Engin-Ustun, Nafiye Yilmaz, Gulcin Yildirim, Aytekin Tokmak, Kudret Erkenekli, Salim Erkaya, Dilek Uygur
      Pages: 299 - 302
      Abstract: A Seval Ozgu-Erdinc, Zeynep Asli Oskovi Kaplan, Yaprak Engin-Ustun, Nafiye Yilmaz, Gulcin Yildirim, Aytekin Tokmak, Kudret Erkenekli, Salim Erkaya, Dilek Uygur
      Journal of Human Reproductive Sciences 2019 12(4):299-302
      Objective: Fetuin-A is a well-known negative acute-phase protein and has been used liberally to predict vascular disease. The aim of this study was to evaluate the association between serum human fetuin-A/alpha2-Heremans–Schmid glycoprotein levels and idiopathic premature ovarian insufficiency (POI). Methods: A total of 75 women were included in this case–control study between January 2013 and December 2013. Serum fetuin-A concentrations were measured in 36 women with idiopathic POI and 39 healthy women with regular cycles. Blood samples were drawn after a 12-h overnight fast and were kept at −80°C for subsequent assay. The serum levels of fetuin-A were assessed by commercial ELISA kits (BioVendor Laboratory Medicine Inc., Brno, Czech Republic) and serum concentration values were expressed as μg/ml. Results: The mean serum fetuin-A levels of idiopathic POI and control women were 229.02 ± 27.79 and 232.37 ± 65.56, respectively, with P = 0.771 (independent samples t-test). Our results showed no statistically significant difference between serum fetuin-A levels of idiopathic POI women and controls. Conclusion: The mean values of serum fetuin-A in idiopathic POI women were not significantly different from controls, which implies that there is no significant association between serum fetuin-A levels and idiopathic POI.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):299-302
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_104_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • A multicenter phase IV study to investigate the immunogenicity of
           recombinant human follicle-stimulating hormone and its impact on clinical
           outcomes in females undergoing controlled ovarian stimulation

    • Authors: Abha Majumdar, Le Hoang, Ly T Loc, Padma Srivastava, Chitra Ramamurthy, Ratnabali Chakravorty, Yogeshwar S Nandanwar, MD Rashmi, Rahul V Mayekar, Jayashree Sridhar, Ganesh H Divekar, James John
      Pages: 303 - 309
      Abstract: Abha Majumdar, Le Hoang, Ly T Loc, Padma Srivastava, Chitra Ramamurthy, Ratnabali Chakravorty, Yogeshwar S Nandanwar, MD Rashmi, Rahul V Mayekar, Jayashree Sridhar, Ganesh H Divekar, James John
      Journal of Human Reproductive Sciences 2019 12(4):303-309
      Context: Therapeutic proteins can cause immune responses, which may have clinical implications. Aims: The aim of the study was to assess the immunogenicity of recombinant human follicle-stimulating hormone (r-hFSH), when used for controlled ovarian stimulation (COS). Settings and Design: Prospective, multicenter study conducted at reproductive medicine clinics in India and Vietnam. Materials and Methods: A total of 285 women, aged 20–40 years, undergoing 354 COS cycles for either intrauterine insemination (IUI) orin vitro fertilization (IVF) were studied. The primary outcome measure was the incidence of development of anti-drug antibodies (ADA) and their neutralization potential. Other outcome measures were follicle development, dose and duration of r-hFSH, positive serum pregnancy test, clinical pregnancy, cycle cancellation, and adverse events (AEs). Statistical Analysis Used: A sample size of 250 was planned. Descriptive statistics are presented. Results: Four patients tested positive for ADA after r-hFSH administration at different time points; all of them tested negative, subsequently. None were found to have neutralization potential. The mean dose and duration of r-hFSH were 816 IU and 8.1 days in IUI and 2183 IU and 9.5 days in IVF, respectively. The serum and clinical pregnancy rates were 12.4% and 11.6% in IUI and 32.7% and 29.9% in IVF cycles, respectively. Seven AEs were reported, including two cases of ovarian hyperstimulation syndrome; two AEs were judged to be serious. Conclusions: The tested r-hFSH has very low immunogenic potential and did not lead to the development of neutralizing antibodies. The overall efficacy and safety of the drug were in-line with existing literature data, and no specific clinical impact of immunogenicity could be identified.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):303-309
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_33_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Does double dose of recombinant human chorionic gonadotropin for final
           follicular maturation in in vitro fertilization cycles improve oocyte
           quality: A prospective randomized study

    • Authors: Neeta Singh, Bhavana Girish, Neena Malhotra, Reeta Mahey, Vanamail Perumal
      Pages: 310 - 315
      Abstract: Neeta Singh, Bhavana Girish, Neena Malhotra, Reeta Mahey, Vanamail Perumal
      Journal of Human Reproductive Sciences 2019 12(4):310-315
      Context: In in vitro fertilization (IVF) cycles, the recommended dose of recombinant human chorionic gonadotropin (r-hCG), for triggering final follicular maturation is 250 μg, although there is some disagreement. Aims: The aim of our study was to assess the effect on the number of mature oocytes retrieved after triggering ovulation in IVF cycles using 250 μg or 500 μg of r-hCG. Settings and Design: Prospective, single-center, randomized study. Subjects and Methods: 100 women undergoing IVF with embryo transfer. The primary outcome measure was the total number of oocytes retrieved per follicle, number of mature oocytes, and number of embryos generated. The secondary outcomes included clinical and biochemical pregnancy rates and incidence of ovarian hyperstimulation syndrome. Results: Mean number of oocytes retrieved (6.5 ± 4.0 vs. 6.4 ± 3.9, P = 0.3) and mean number of mature oocytes (4.0 ± 2.3 vs. 3.2 ± 2.3, P = 0.09) were similar in the two groups; however, mean number of oocytes retrieved per follicle was found to be higher with 500 μg r-hCG (67.4 ± 23.9 vs. 77.5 ± 23.3, P = 0.04). In the subgroup of poor responder women, there was a significant increase in the number of mature oocytes retrieved with double dose of r-hCG (2.2 ± 1.8 vs. 3.7 ± 1.9, P = 0.06), leading to improvement in fertilization and clinical pregnancy rates. Conclusions: Double dose of r-hCG for final follicular maturation in IVF cycles resulted in improvement in mean number of oocytes per follicle but did not result in improved pregnancy rates in the women. In the subset of poor responders, 500 μg r-hCG seems to be more advantageous than the lower dose, although larger randomized trials are needed to generalize this strategy.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):310-315
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_125_18
      Issue No: Vol. 12, No. 4 (2019)
       
  • Outcomes of intracytoplasmic sperm injection in infertile men with
           nontense vaginal hydrocele: A prospective cohort study

    • Authors: Adel E Elgergawy, Ayman S Dawood, Ahmed M Abbas, Salah A. M Nagla
      Pages: 316 - 320
      Abstract: Adel E Elgergawy, Ayman S Dawood, Ahmed M Abbas, Salah A. M Nagla
      Journal of Human Reproductive Sciences 2019 12(4):316-320
      Objective: To evaluate the effect of nontense vaginal hydrocele in male partner with oligoasthenospermia on the success rates of the intracytoplasmic sperm injection (ICSI). Patients and Methods: Enrolled patients (n = 60) were divided into two groups: Group I who have oligoasthenospermia with nontense vaginal hydrocele (study group) and Group II who have oligoasthenospermia with no hydrocele group (control group). The primary outcomes included the fertilization and pregnancy rates whereas the secondary outcomes included any complications occurred. Results: There were no differences in demographic characteristics between both groups. Semen parameters were poorer in the hydrocele group than in the nonhydrocele group regarding count and motility (P < 0.001). The volume of testis was reduced significantly in the hydrocele group (P < 0.001). The results of ICSI regarding fertilization rate, number and quality of developed embryos, and pregnancy rates are not statistically different between both groups. Conclusion: Hydrocele affects both sperm count and motility, but it has no effects on ICSI outcomes. Clinical pregnancy rate was comparable in patients with or without hydrocele. Hence, the surgical management of hydrocele before ICSI is not recommended.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):316-320
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_45_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Is it time to move toward freeze-all strategy? – A retrospective
           study comparing live birth rates between fresh and first frozen blastocyst
           transfer

    • Authors: Reeta Biliangady, Rubina Pandit, Nutan Kumari Tudu, Poornima Kinila, Uma Maheswari, Indu S. T Gopal, Ambika G Swamy
      Pages: 321 - 326
      Abstract: Reeta Biliangady, Rubina Pandit, Nutan Kumari Tudu, Poornima Kinila, Uma Maheswari, Indu S. T Gopal, Ambika G Swamy
      Journal of Human Reproductive Sciences 2019 12(4):321-326
      Background: Cryopreservation of all embryos followed by transfer in subsequent cycles has emerged as an effective alternative to fresh embryo transfer (ET) in order to overcome the negative effect of superovulation on endometrial receptivity. Aims: The aim of this study was to compare the reproductive outcomes between fresh ET and first frozen ET (FET) from “freeze-all” group of embryos. Setting: This study was conducted at a private in vitro fertilization center. Design: This was a retrospective study. Patients and Methods: A total of 503 patients fulfilling the inclusion criteria between 2012 and 2017 were included. Of 503, 386 patients underwent fresh ET and 117 patients underwent FET following cryopreservation of all embryos. The results of only first FET were considered to eliminate the confounding factor of poor-quality embryos in subsequent transfer. Results: FET resulted in statistically significant higher live birth rate (44.44% vs. 33.41%), implantation rate (45.08% vs. 30.22%), and clinical pregnancy rate (57.26% vs. 38.6%) compared to fresh ETs. No difference was observed in the abortion rate between the two groups. Conclusion: Reproductive outcomes were significantly better in the freeze-all group compared to fresh ET suggesting that the altered hormone levels during controlled ovarian stimulation could mediate an asynchrony between the endometrium and the transferred embryos, leading to implantation failure.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):321-326
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_146_18
      Issue No: Vol. 12, No. 4 (2019)
       
  • What are the predictive factors for preeclampsia in oocyte
           recipients?

    • Authors: Celine Pimentel, Duros Solene, Jaffre Fr&#233;d&#233;rique, Bouzille Guillaume, Leveque Jean, Le Lous Ma&#235;la
      Pages: 327 - 333
      Abstract: Celine Pimentel, Duros Solene, Jaffre Frédérique, Bouzille Guillaume, Leveque Jean, Le Lous Maëla
      Journal of Human Reproductive Sciences 2019 12(4):327-333
      Objectives: Oocyte donation pregnancies are more frequently complicated by preeclampsia (PE), which cause significant fetal-maternal morbidity and mortality. Our objective was to determine risk factors for PE in oocyte recipients (OR). Our secondary objective was to describe the course of pregnancy and the neonatal outcome in this group. Methods: This was a historical-prospective study. One hundred and fifty OR who gave birth to children at over 22 weeks of amenorrhea between January 2010 and June 2018 were included in the study. Results: Risk factors for PE in OR found in univariate analysis were as follows: primiparity, primipaternity, body mass index (BMI), and anti-Müllerian hormone (AMH) of the OR and age and AMH of the oocyte donors (OD). In multivariate analysis, the BMI of the OR (odds ratio [OR]: 1.2, 95% confidence interval [CI]: [1.1–1.4], P = 0.0474) and the AMH of the OD (OR: 1.2, 95% CI: [1.2–1.4], P = 0.0481) were found to be statistically significant risk factors for PE. In addition, we observed an increase in the rate of prematurity in the OR that were not associated with fetal growth retardation, despite the occurrence of PE. Conclusion: In OR, the allogeneic nature of pregnancy induces an increased risk of PE, the pathophysiology of which seems different from that in other methods of conception. Thus, risk factors for PE should be reconsidered to take into account the impact of certain characteristics of OD such as age and AMH.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):327-333
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_43_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Predictors of metabolic syndrome among polycystic ovary syndrome sisters

    • Authors: Bindu Kulshreshtha, Neera Sharma, Shubhi Pant, Akhila Prasad, Anubhuti Chitkara, Bhawna Pahuja, Isha Pahuja
      Pages: 334 - 340
      Abstract: Bindu Kulshreshtha, Neera Sharma, Shubhi Pant, Akhila Prasad, Anubhuti Chitkara, Bhawna Pahuja, Isha Pahuja
      Journal of Human Reproductive Sciences 2019 12(4):334-340
      Aims: Metabolic syndrome among PCOS sisters may vary depending on the phenotype. The aim of the present study was to analyze the prevalence of metabolic syndrome among different phenotypes of PCOS sisters. Design: Case control study. Materials and Methods: Two hundred sisters of PCOS patients and 99 age matched healthy controls underwent history, clinical examination, biochemical parameters for metabolic syndrome and hormonal assessment. Results: Of 200 sisters, 85 were unaffected (UA group), 21 sisters had hyperandrogenemia (HA group), and 94 sisters had irregular periods or hyperandrogenemia. We observed that the frequency of metabolic syndrome among PCOS sisters was comparable to age and weight matched controls (30% vs 27%). The prevalence of metabolic syndrome was higher in HA and AFFECTED sisters (around 30% in both) compared to UA sisters (20%). The presence of metabolic syndrome was significantly associated with age, BMI, HOMA-IR and free testosterone. After correction for age and BMI, metabolic syndrome was significantly associated with HOMA-IR (P - 0.05) and free testosterone (P - 0.03). Conclusion: Based on above findings, we conclude that affected sisters and those with higher age, BMI and hyperandrogenemia have a high risk of metabolic syndrome compared to unaffected sisters.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):334-340
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_172_18
      Issue No: Vol. 12, No. 4 (2019)
       
  • India's first child using PGT-M, PGT-A and HLA matching for helping a
           sibling having β-thalassemia major

    • Authors: Jwal M Banker, Parul Arora, Rajni Khajuria, Manish Banker
      Pages: 341 - 344
      Abstract: Jwal M Banker, Parul Arora, Rajni Khajuria, Manish Banker
      Journal of Human Reproductive Sciences 2019 12(4):341-344
      β-thalassemia is a common single-gene disorder in India, with hematopoietic stem cell transplantation (HSCT) being the only cure. HSCT with matched unrelated donor is less successful, whereas finding a human leukocyte antigen (HLA)-matched related donor is difficult. Preimplantation genetic testing for monogenic diseases (PGT-M) with HLA matching is a novel option to have a matched sibling for HSCT for couples having an affected child. We present the first such case report in India. A couple, both carriers of β-thalassemia and having an affected son, underwent PGT-M with HLA matching combined with preimplantation genetic testing for aneuploidies of embryos to have a β - thalassemia-free child. This resulted in birth of a 10/10 HLA-matched sibling.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):341-344
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_50_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Swyer syndrome with heterotopic adrenal cortical tissue in streak gonads:
           A rare case and review of literature

    • Authors: Manu Goyal, Shuchita Batra, Pratibha Singh, Shashank Shekhar, Poonam Elhence
      Pages: 345 - 347
      Abstract: Manu Goyal, Shuchita Batra, Pratibha Singh, Shashank Shekhar, Poonam Elhence
      Journal of Human Reproductive Sciences 2019 12(4):345-347
      Swyer syndrome is a 46 XY pure gonadal dysgenesis. Affected individuals are phenotypically female with external female genitalia, hypoplastic Mullerian structures, and the presence of streak gonads. Gonadectomy is indicated due to increased risk of development of malignancy in streak gonads. We hereby report a case of 15-year-old patient with Swyer syndrome who underwent laparoscopic gonadectomy. Histopathological examination showed streak gonads with the presence of accessory adrenal cortical tissue. The patient was put on hormonal replacement therapy postsurgery. Heterotopic adrenal rest may be an incidental finding in normal ovary and testis. Its presence in streak gonads has never been reported, and we propose a theory of increased risk of gonadal and adrenal tumors, possibly because of mutations in disorders of sex differentiation.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):345-347
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_44_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Complete androgen insensitivity syndrome: Dilemmas for further management
           after gonadectomy

    • Authors: Pratibha Singh, Meenakshi Gothwal, Garima Yadav, Kuldeep Singh
      Pages: 348 - 350
      Abstract: Pratibha Singh, Meenakshi Gothwal, Garima Yadav, Kuldeep Singh
      Journal of Human Reproductive Sciences 2019 12(4):348-350
      Complete androgen insensitivity syndrome is a rare condition, wherein a genetic male is phenotypically female and is raised as a female. Treatement requires timely gonadectomy, need for long term hormonal replaceent therapy, psycological and genetic counseling. The type, dose, duration of hrt is not well studied. Reproductive issues also need to be addressed in these young woman. We report here a case of complete androgen insensitivity which posed a quandary for management of long term bone health. Review of literature for management is discussed. These cases are best managed by a multi-disciplenary team comprising of gynecologist, geneticist, endocrinologist and clinical psycologist or psychiatrist.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):348-350
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_151_18
      Issue No: Vol. 12, No. 4 (2019)
       
  • Sildenafil Citrate: Novel Therapy in the Management of Ovarian Torsion

    • Authors: Kedar N Ganla, Rana A Choudhary, Priyanka H Vora, Umesh V Athavale
      Pages: 351 - 354
      Abstract: Kedar N Ganla, Rana A Choudhary, Priyanka H Vora, Umesh V Athavale
      Journal of Human Reproductive Sciences 2019 12(4):351-354
      Ovarian torsion is defined as partial or complete rotation of ovarian vascular pedicle, leading to the obstruction of venous outflow and arterial inflow. It is an emergency condition with an incidence of 2%–15% in patients with adnexal masses. The main risk in ovarian torsion is an ovarian mass or an enlarged ovary with a long pedicle. Due to the rotation of ovarian tissue axis on its vascular pedicle, there is compression of vessels followed by stromal edema, hemorrhagic infarction, and necrosis of adnexa. Expedient diagnosis poses a difficult challenge because clinical presentation is a variable and often misleading. We report a case of right ovarian torsion after oocyte retrieval for in vitro fertilization, where vaginal sildenafil citrate was successfully used to reduce ovarian edema by improving venous drainage. It also helped in maintaining ovarian tissue perfusion and preventing reperfusion injury and spontaneous detorsion of the ovary without any surgical intervention.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):351-354
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_52_19
      Issue No: Vol. 12, No. 4 (2019)
       
  • Heterotopic cervical pregnancy: A rare case treated by transvaginal
           aspiration

    • Authors: Sindhu Bhairavi, Soumyaroop Dash, Sebanti Dash
      Pages: 355 - 357
      Abstract: Sindhu Bhairavi, Soumyaroop Dash, Sebanti Dash
      Journal of Human Reproductive Sciences 2019 12(4):355-357
      Cervical pregnancy is a rare form of ectopic pregnancy. Heterotopic cervical pregnancy is much more rare scenario. This is a case of Heterotopic cervical pregnancy treated successfully by transvaginal ultrasound guided aspiration.
      Citation: Journal of Human Reproductive Sciences 2019 12(4):355-357
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/jhrs.JHRS_147_18
      Issue No: Vol. 12, No. 4 (2019)
       
  • Comparative Study of Serum Progesterone Levels at the Time of Human
           Chorionic Gonadotropin Trigger and Ovum Pickup in Predicting Outcome in
           Fresh in vitro Fertilization Cycles

    • Pages: 358 - 358
      Abstract:
      Journal of Human Reproductive Sciences 2019 12(4):358-358

      Citation: Journal of Human Reproductive Sciences 2019 12(4):358-358
      PubDate: Tue,17 Dec 2019
      DOI: 10.4103/0974-1208.273123
      Issue No: Vol. 12, No. 4 (2019)
       
 
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