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CARDIOVASCULAR DISEASES (338 journals)            First | 1 2     

Showing 201 - 338 of 338 Journals sorted alphabetically
JMIR Cardio     Open Access  
Jornal Vascular Brasileiro     Open Access  
Journal of Clinical & Experimental Cardiology     Open Access   (Followers: 5)
Journal of Arrhythmia     Open Access  
Journal of Cardiac Critical Care TSS     Open Access   (Followers: 2)
Journal of Cardiac Failure     Hybrid Journal   (Followers: 1)
Journal of Cardio-Thoracic Medicine     Open Access   (Followers: 3)
Journal of Cardiobiology     Open Access  
Journal of Cardiology     Full-text available via subscription   (Followers: 7)
Journal of Cardiology and Cardiovascular Medicine     Open Access   (Followers: 3)
Journal of Cardiology and Therapy     Open Access   (Followers: 2)
Journal of Cardiology Cases     Full-text available via subscription  
Journal of Cardiopulmonary Rehabilitation and Prevention     Hybrid Journal   (Followers: 7)
Journal of Cardiothoracic and Vascular Anesthesia     Hybrid Journal   (Followers: 8)
Journal of Cardiothoracic Surgery     Open Access   (Followers: 5)
Journal of Cardiothoracic Trauma     Open Access  
Journal of Cardiothoracic-Renal Research     Full-text available via subscription  
Journal of Cardiovascular Computed Tomography     Hybrid Journal   (Followers: 2)
Journal of Cardiovascular Development and Disease     Open Access   (Followers: 1)
Journal of Cardiovascular Disease Research     Open Access   (Followers: 2)
Journal of Cardiovascular Diseases & Diagnosis     Open Access   (Followers: 1)
Journal of Cardiovascular Echography     Open Access   (Followers: 1)
Journal of Cardiovascular Electrophysiology     Hybrid Journal  
Journal Of Cardiovascular Emergencies     Open Access  
Journal of Cardiovascular Magnetic Resonance     Open Access   (Followers: 1)
Journal of Cardiovascular Medicine     Hybrid Journal   (Followers: 2)
Journal of Cardiovascular Medicine and Cardiology     Open Access   (Followers: 2)
Journal of Cardiovascular Nursing     Hybrid Journal   (Followers: 19)
Journal of Cardiovascular Pharmacology     Hybrid Journal   (Followers: 7)
Journal of Cardiovascular Pharmacology and Therapeutics     Hybrid Journal   (Followers: 2)
Journal of Cardiovascular Surgery     Full-text available via subscription   (Followers: 5)
Journal of Cardiovascular Translational Research     Hybrid Journal   (Followers: 2)
Journal of Clinical and Preventive Cardiology     Open Access   (Followers: 2)
Journal of Clinical Hypertension     Hybrid Journal   (Followers: 7)
Journal of Congenital Cardiology     Open Access   (Followers: 4)
Journal of Echocardiography     Hybrid Journal   (Followers: 5)
Journal of Electrocardiology     Hybrid Journal   (Followers: 1)
Journal of Endovascular Therapy     Full-text available via subscription   (Followers: 5)
Journal of Geriatric Cardiology     Open Access   (Followers: 4)
Journal of Human Hypertension     Hybrid Journal   (Followers: 3)
Journal of Hypertension     Hybrid Journal   (Followers: 13)
Journal of Indian College of Cardiology     Hybrid Journal  
Journal of Interventional Cardiac Electrophysiology     Hybrid Journal  
Journal of Interventional Cardiology     Open Access   (Followers: 2)
Journal of Molecular and Cellular Cardiology     Hybrid Journal   (Followers: 4)
Journal of Nuclear Cardiology     Hybrid Journal  
Journal of Rare Cardiovascular Diseases     Open Access   (Followers: 1)
Journal of Respiratory and CardioVascular Physical Therapy     Open Access   (Followers: 3)
Journal of Stroke and Cerebrovascular Diseases     Hybrid Journal   (Followers: 39)
Journal of the American College of Cardiology     Hybrid Journal   (Followers: 68)
Journal of the American Heart Association     Open Access   (Followers: 17)
Journal of the American Society of Echocardiography     Hybrid Journal   (Followers: 6)
Journal of the CardioMetabolic Syndrome     Hybrid Journal   (Followers: 1)
Journal of the Egyptian Society of Cardio-Thoracic Surgery     Open Access  
Journal of The Indian Academy of Echocardiography & Cardiovascular Imaging     Open Access   (Followers: 1)
Journal of the Practice of Cardiovascular Sciences     Open Access  
Journal of the Saudi Heart Association     Open Access  
Journal of Thoracic and Cardiovascular Surgery     Hybrid Journal   (Followers: 15)
Journal of Thrombosis and Haemostasis     Hybrid Journal   (Followers: 78)
Journal of Thrombosis and Thrombolysis     Hybrid Journal   (Followers: 34)
Journal of Vascular Access     Hybrid Journal   (Followers: 3)
Journal of Vascular Diagnostics     Open Access  
Journal of Veterinary Cardiology     Full-text available via subscription   (Followers: 7)
JRSM Cardiovascular Disease     Open Access  
Kardiologia Inwazyjna     Open Access  
Kardiologie up2date     Hybrid Journal   (Followers: 3)
Kerala Heart Journal     Open Access   (Followers: 1)
Microvascular Research     Hybrid Journal   (Followers: 2)
Monaldi Archives for Chest Disease     Open Access  
Nadciśnienie Tętnicze w Praktyce     Open Access  
Nature Reviews Cardiology     Full-text available via subscription   (Followers: 21)
Nepalese Heart Journal     Open Access  
Netherlands Heart Journal     Hybrid Journal   (Followers: 1)
Nigerian Journal of Cardiology     Open Access   (Followers: 1)
Nigerian Journal of Cardiovascular & Thoracic Surgery     Open Access  
Nutrition, Metabolism and Cardiovascular Diseases     Hybrid Journal   (Followers: 12)
Open Cardiovascular Medicine Journal     Open Access  
Open Heart     Open Access   (Followers: 1)
Open Hypertension Journal     Open Access  
Open Journal of Cardiovascular Surgery     Open Access   (Followers: 1)
Operative Techniques in Thoracic and Cardiovascular Surgery     Full-text available via subscription   (Followers: 2)
Pakistan Heart Journal     Open Access   (Followers: 2)
Parkinsonism & Related Disorders     Hybrid Journal   (Followers: 8)
Pediatric Cardiology     Hybrid Journal   (Followers: 10)
Platelets     Hybrid Journal   (Followers: 3)
Pregnancy Hypertension: An International Journal of Women's Cardiovascular Health     Hybrid Journal   (Followers: 4)
Prenatal Cardiology     Open Access   (Followers: 2)
Preventive Cardiology     Hybrid Journal   (Followers: 2)
Progress in Cardiovascular Diseases     Hybrid Journal   (Followers: 3)
Progress In Cardiovascular Nursing     Hybrid Journal  
Progress in Pediatric Cardiology     Full-text available via subscription   (Followers: 4)
Research in Cardiovascular Medicine     Open Access  
Research Journal of Cardiology     Open Access   (Followers: 1)
Research Reports in Clinical Cardiology     Open Access  
Resuscitation     Hybrid Journal   (Followers: 43)
Reviews in Vascular Medicine     Full-text available via subscription  
Revista Argentina de Cardiología     Open Access  
Revista Brasileira de Cardiologia Invasiva     Open Access  
Revista Brasileira de Cirurgia Cardiovascular     Open Access   (Followers: 1)
Revista Chilena de Cardiología     Open Access  
Revista Colombiana de Cardiologia     Open Access  
Revista Costarricense de Cardiología     Open Access  
Revista Cubana de Angiología y Cirugía Vascular     Open Access  
Revista Cubana de Cardiología y Cirugía Cardiovascular     Open Access  
Revista Española de Cardiología     Open Access  
Revista Española de Cardiología (English Edition)     Full-text available via subscription  
Revista Española de Cardiología Suplementos     Full-text available via subscription  
Revista Latinoamericana de Hipertension     Open Access  
Revista Portuguesa de Cardiologia     Open Access  
Revista Portuguesa de Cardiologia (English Edition)     Open Access  
Revista Uruguaya de Cardiologia     Open Access  
Russian Journal of Cardiology     Open Access  
SA Heart     Open Access  
Scandinavian Cardiovascular Journal     Hybrid Journal   (Followers: 2)
Seminars in Cardiothoracic and Vascular Anesthesia     Hybrid Journal   (Followers: 3)
Seminars in Cardiovascular Medicine     Open Access  
Seminars in Thoracic and Cardiovascular Surgery     Full-text available via subscription   (Followers: 5)
Seminars in Thoracic and Cardiovascular Surgery: Pediatric Cardiac Surgery Annual     Full-text available via subscription   (Followers: 6)
Seminars in Thrombosis and Hemostasis     Hybrid Journal   (Followers: 46)
Stroke     Hybrid Journal   (Followers: 94)
Stroke and Vascular Neurology     Open Access   (Followers: 3)
Structural Heart : The Journal of the Heart Team     Hybrid Journal  
Systemic Hypertension     Open Access  
Texas Heart Institute Journal     Open Access   (Followers: 2)
The VAD Journal     Open Access  
Therapeutic Advances in Cardiovascular Disease     Open Access  
Therapeutic Advances in Chronic Disease     Open Access   (Followers: 8)
Thoracic and Cardiovascular Surgeon     Hybrid Journal   (Followers: 2)
Thoracic and Cardiovascular Surgeon Reports     Open Access   (Followers: 2)
Trends in Cardiovascular Medicine     Hybrid Journal   (Followers: 4)
Trials     Open Access   (Followers: 4)
University Heart Journal     Open Access   (Followers: 1)
US Cardiology Review     Open Access   (Followers: 1)
Vascular and Endovascular Review     Open Access   (Followers: 1)
World Journal for Pediatric and Congenital Heart Surgery     Hybrid Journal   (Followers: 4)
World Journal of Cardiovascular Diseases     Open Access   (Followers: 2)
World Journal of Cardiovascular Surgery     Open Access   (Followers: 2)
Zeitschrift für Komplementärmedizin     Hybrid Journal  

  First | 1 2     

Similar Journals
Journal Cover
The VAD Journal
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2378-2706
Published by U of Kentucky Homepage  [6 journals]
  • What Did We Learn about VADs in 2017'

    • Authors: Maya Guglin
      PubDate: Tue, 30 Jan 2018 19:16:35 PST
  • Management of aortic insufficiency in patients with left ventricular
           assist device ̶ a retrospective analysis

    • Authors: Hartmuth B. Bittner
      Abstract: Background: Aortic insufficiency is increasingly recognized as a complication of left ventricular assist device (LVAD) support and may lead to clinical decompensation requiring correction. This article describes experiences in managing patients presenting with concomitant aortic insufficiency and with de novo aortic insufficiency following left ventricular assist device implantations.Methods: All patients undergoing LVAD implantation between 2012 and 2014 were included in this retrospective analysis if aortic valve insufficiency was present on implantation or newly developed (de novo) after implantation. Moderate to severe aortic valve insufficiency was corrected at implantation.Results: The data of 39 patients were included. At the time of LVAD implantation, moderate to severe aortic valve insufficiency was present in 3 patients and was corrected by bioprosthetic valve replacement (2 patients) and by bioprosthetic valve replacement associated with ascending aorta with hemi arch replacement with a graft due to ascending aortic aneurysm (one patient). Four patients developed moderate to severe aortic insufficiency after LVAD surgery. Treatment with conservative medical management was successful in 3 patients. One patient underwent transcatheter aortic valve occlusion using an Amplatzer closure device after failure of medical management.Conclusions: Concomitant aortic valve replacement with LVAD implantation is a safe and viable option in managing aortic valve insufficiency. De novo aortic insufficiency may lead to recurrent heart failure and presents a clinical treatment challenge following successful LVAD support; the most appropriate and effective treatment option awaits definition.
      PubDate: Mon, 22 Jan 2018 09:26:27 PST
  • Approach to Unresponsive Patient with LVAD

    • Authors: Maya Guglin
      PubDate: Sun, 07 Jan 2018 14:51:23 PST
  • Unresponsive Patient with LVAD: A Case Series

    • Authors: Ameer Z. Musa et al.
      Abstract: Mechanical circulatory support (MCS) for patients with advanced heart failure (HF) is becoming more commonplace as technology has progressed and reliability of these systems has improved. We report our experience with three patients with cardiopulmonary arrest in the hospital and propose a protocol for the prompt assessment and treatment of an unresponsive patient with a LVAD in place. We presented three cases of unresponsive patients on LVAD support with low flow or no flow through the LVAD. Although all three of them were alive after resuscitation, none survived to discharge. In all three cases, there were no flaws in LVAD per se, with power source and controller appropriately attached, and the pump functioning normally. The low flow state was secondary to non-cardiac conditions (respiratory acidosis, dehydration, and stroke). In early 2017 we developed our algorithm for unresponsive LVAD patients. Utilization of LVAD flow, which can be obtained quickly and non-invasively at the bedside of a patient is used to direct resuscitation efforts in this proposed protocol. Rapid and standardized protocol for resuscitation of LVAD patients with in-hospital cardiopulmonary arrest is necessary to decrease morbidity and mortality. Further investigation regarding the best practice in this clinical scenario is evolving and further studies are needed.
      PubDate: Wed, 03 Jan 2018 16:11:17 PST
  • Capsule Endoscopy in Left Ventricular Assist Device Patients:
           Retrospective Review of Efficacy and Necessity

    • Authors: Gaurang N. Vaidya et al.
      Abstract: Introduction: Capsule endoscopy (CE) is mainstream in the evaluation of obscure gastrointestinal bleeding (GIB) in the general population. However, the diagnostic and therapeutic impact of CE in LVAD patients susceptible to transient bleeding remains largely unexplored. This study aimed to assess the benefits of CE in the evaluation of LVAD associated GIB.Methods: Retrospective review of patients implanted with a continuous flow LVAD who underwent inpatient capsule endoscopy (CE) between January 2014 and May 2017 at our center. Identification of lesions with high bleeding potential or presence of frank blood were considered abnormal findings on CE study.Result: Twenty-five inpatients who underwent 41 CE were identified. All patients presented with GIB and had preceding negative upper endoscopy and colonoscopy in the past 4 weeks. On the first capsule in each patient, 19 had interpretable images, abnormal findings were detected in 5 patients (high risk lesion in 3, frank blood in 2), four of these underwent an enteroscopy and only 2 (8%) patients had confirmation of the capsule findings with APC treatment (true positive). Excluding patients with malfunction, LVAD interference and poor bowel prep, 14 patients had negative/equivocal CE, of which 4 underwent enteroscopy due to continued bleeding and 2 of these patients had treatable culprit lesions (false negative). A total of 17 (68%) patients were discharged without any therapeutic intervention irrespective of the success or findings on CE due to clinical stabilization. Twenty patients (80%) had recurrence in a mean 154 days.As expected, repeat capsules in the same admission increased the diagnostic yield (p=0.031)Only nine patients (36%) had capsule-image evidence of reaching the cecum while 4 patients (16%) had retention which had to be retrieved without further complication.Conclusion: This study demonstrated that evaluation of GIB with CE is feasible and safe but was associated with a low diagnostic yield and low conversion to therapeutic intervention. With a true positive yield of 4% in our cohort, the efficacy and cost-effectiveness of CE in the LVAD population is debatable. The role of CE in LVAD patients may need to be reevaluated.An identification of patients who would benefit from a capsule-first approach would allow optimum utilization of resources and reduce healthcare expenditure.
      PubDate: Thu, 28 Sep 2017 21:56:28 PDT
  • Anticoagulation Monitoring in Left Ventricular Assist Device (LVAD)

    • Authors: Adam Sieg et al.
      Abstract: The use of left ventricular assist devices (LVAD) provides a treatment strategy for advanced heart failure patients to prolong life and serve as a mediator (bridge to transplant) until an organ becomes available in patients considered suitable candidates for heart transplantation. The use of LVAD therapy is complicated by the constant risk of bleeding and thrombotic events. We reviewed and analyzed the effectiveness of our current heparin protocol with respect to overall anticoagulation and time in therapeutic range (TTR). Our analysis demonstrated that patients did not achieve therapeutic anticoagulation for at least 24 hours following initiation of heparin and that only 40% of the time patients were considered therapeutic. Even after patients achieved a therapeutic activated plasma thromboplastin time (aPTT) TTR was only approximately 50% with less than 50% of tests resulting within range. Individual centers should perform ongoing assessment of effectiveness of individual heparin protocol for LVAD patients to ensure anticoagulation is optimized in these highly complex patients.
      PubDate: Wed, 06 Sep 2017 18:06:20 PDT
  • Right ventricle chest compressions: do we need a new paradigm for LVAD
           patients needing resuscitation' A case report.

    • Authors: Arvind Bhimaraj et al.
      Abstract: The use of chest compressions in patients with left ventricular assist devices (LVAD) have been viewed to cause a potential damage to the outflow graft and hence have been a topic of controversy. We report a case of a LVAD patient who needed chest compressions during resuscitation for severe right ventricular failure. With the presence of trans-esophageal echocardiogram we noticed that the chest compressions did not need to be full ACLS compressions but modified to gentle right ventricular (RV) compressions in order to move blood into a normally functioning LVAD. We report this as a call for the LVAD medical providers to rethink concepts of standard resuscitation.
      PubDate: Sun, 06 Aug 2017 14:11:15 PDT
  • Left Ventricular Assist Device is a Viable Therapy in End Stage
           Hypertrophic Cardiomyopathy

    • Authors: Mirnela Byku et al.
      Abstract: Left Ventricular Assist Device (LVAD) therapy use is increasing rapidly in advanced heart failure (HF). Little data exists on the application of this therapy in patients with advanced HF due to Hypertrophic Cardiomyopathy (HCM). Altered ventricular geometry, thickened septum and reduced LV end-diastolic diameter (LVEDD) in HCM may lead to increased suction events, arrhythmias and inflow cannula malfunction.We hypothesized that patients with end stage HCM benefit from LVAD therapy and have a similar rate of complications to those with ischemic or dilated CM.Between 2009 and 2014, 5 patients with end stage HCM (HCM and EFWe conclude that select patients with end stage HCM may benefit from LVAD therapy with a similar rate of complications compared to traditional candidates. Additional study is warranted to further evaluate durable mechanical support in this population.
      PubDate: Tue, 04 Jul 2017 14:46:12 PDT
  • Paranormal activity: Para-Esophageal/Gastric Hemorrhage in a Patient with
           a HeartMate II LVAD

    • Authors: Anna Stone et al.
      Abstract: In this report we present an unusual case of non-traumatic, spontaneous para-esophageal/para-gastric hemorrhage requiring multiple units of red blood cells in a female patient with a continuous flow left ventricular assist device. She presented with dysphagia and atypical chest pain 18 months post implantation, on the recommended anticoagulation regimen for HeartMate II support of ASA 81mg and international normalized ratio goal (INR) of 2-3 and was successfully managed with conservation support, volume resuscitation and multiple transfusions. Non-traumatic causes of acute bleeding, including acquired platelet dysfunction are considered.
      PubDate: Wed, 24 May 2017 18:01:09 PDT
  • Fatal Flaw - Driveline Fracture as a Rare but Serious Complication of
           Mechanical Circulatory Support with Left Ventricular Assist Devices

    • Authors: Yuri Boyechko et al.
      Abstract: Background: Patients with advanced heart failure have seen decreased mortality and improved quality of life due to mechanical circulatory support with left ventricular assist devices (LVAD). Regardless of such outcomes, many complications still exist and remain a significant cause of morbidity and mortality. Our purpose is to study the prevalence, clinical course, and outcomes specifically of patients with LVAD driveline (DL) fractures.Methods: This single-center, retrospective review included all patients at our institution who had continuous flow LVADs and experienced DL fracture/injury from January 2012 - December 2015.Results: Thirteen of 110 LVAD patients (11.8%) had DL fractures (Table 1). Time from implant to time of fracture was 23+/-16.5 months. The majority of fractures were external (62%), due to trauma (i.e. cut during dressing change). Internal injury, proximal to the cutaneous exit site, occurred in 38% of patients, usually due to unknown causes. Only one patient (7.6%) survived on LVAD support. One survived LVAD explant, two underwent pump exchange, and four others underwent heart transplantation. The remaining 5 expired. All patients with untreated internal fractures died (60%).Conclusions: Driveline fracture is a rare complication of LVAD and is often lethal when it occurs. Only one patient in our cohort survived without the need for heart transplant, LVAD exchange, or explant. Internal driveline fractures portend a very high mortality. Driveline fracture, especially one that cannot be promptly repaired or if internal fracture is suspected, requires immediate pump exchange or listing for heart transplant.
      PubDate: Sun, 30 Apr 2017 14:31:16 PDT
  • Does Left Ventricular Assist Device Implantation Affect Driving Patterns
           in Patients With End-Stage Heart Failure'

    • Authors: Mamatha Pinninti et al.
      Abstract: Background In 2012, the Canadian Society of Cardiology indicated that patients supported with left ventricular assist device (LVAD) may drive a private vehicle 2 months after implantation, provided they are deemed clinically stable. Objective evidence supporting this recommendation is limited. We sought to compare data regarding driving habits in our patients following LVAD implantation.MethodsA standard questionnaire addressing driving patterns before and after LVAD implantation was sent to all living patients who had received an LVAD between January 2010 and January 2014. Ninety-four of 124 patients responded (average age 58 years, 69.2% men, 77.7% bridge to transplant).ResultsPrior to LVAD, all were living at home, 33% were employed, and 93% were driving. Sixty-nine percent indicated they drove after LVAD implantation; they were younger (56 vs 62 years, p=0.02) and had providers recommendation (p=0.004). Four of seven patients who had not driven before started driving (pConclusionsMost patients returned to driving after LVAD implantation. A minority had LVAD-associated alarms that were easily addressed. We suggest inclusion of driving habits in registries to provide clarity on the safety of driving while being supported with LVAD.
      PubDate: Thu, 16 Mar 2017 15:26:06 PDT
  • Venoarterial extracorporeal membrane oxygenation for cardiogenic shock: a
           retrospective analysis based on the etiology of shock

    • Authors: Andrew Burchett et al.
      Abstract: Abstract:Background: We performed a retrospective analysis to evaluate the efficacy of VA-ECMO support in cardiogenic shock based on various etiologies.Methods: We retrospectively analyzed 99 patients supported with VA-ECMO from January 1, 2012 to January 1, 2015. Outcomes included survival to discontinuation of VA-ECMO support and survival to hospital discharge. The etiologies of cardiogenic shock included cardiac arrest (CPR), acute myocardial infarction (AMI), decompensated congestive heart failure (CHF), pulmonary embolism (PE), right ventricular failure (RVF) not secondary to an acute pulmonary embolism, and post-cardiotomy syndrome (PCS). The PCS group was used as a reference group; odds ratios were estimated and Fisher’s exact tests were performed to compare each other group to the reference.Results: Patients supported with VA-ECMO due to PE and CHF had better survival to hospital discharge (83.3% and 54.2%, with p = 0.003 and p = 0.011, respectively) versus the PCS group (7.7%). The PE, CHF, and AMI groups had statistically improved survival to VA-ECMO discontinuation. There was no statistically significant difference in survival to VA-ECMO discontinuation or hospital discharge in four subgroup analyses.Conclusions: Patients supported with VA-ECMO in cardiogenic shock due to PE or CHF demonstrated increased rates of survival to hospital discharge when compared to the PCS group. This study also highlights the need for a more uniform system of categorizing etiologies of cardiogenic shock.
      PubDate: Thu, 16 Mar 2017 15:26:02 PDT
  • Reversible Mitral Regurgitation as a Complication of Impella® 5.0

    • Authors: Katrina A. Bidwell et al.
      Abstract: The Impella® is a ventricular assist device used for temporary left ventricular support and has been approved for use since 2008. In this report we present a case of a patient who experienced mitral regurgitation as a complication shortly after placement of an Impella® as well as a brief literature review. To our knowledge this is the first such case demonstrating resolution of iatrogenic mitral regurgitation with removal of the device as opposed to permanent damage.
      PubDate: Thu, 16 Mar 2017 15:11:05 PDT
  • Common clinical dilemmas in left ventricular assist device therapy: A
           glimpse into current trends

    • Authors: Ahmet Kilic et al.
      Abstract: BackgroundLeft ventricular assist device (LVAD) therapy has been thrust into the forefront of surgical treatment for advanced heart failure (HF). Despite advancements in survival and quality of life with these devices, the multi-disciplinary care for these patients remains far from standardized across institutions.Methods A survey of current practices in LVAD was carried out at the St. Jude Medical User’s meeting representing a variety of caregivers including cardiac surgeons, HF cardiologists, non-HF cardiologists, advanced practice providers and ventricular assist device coordinators, with representation from several continents. Utilizing an audience response system, eleven questions were asked related to the demographics of the audience, left ventricular assist device patient selection and patient management.ResultsA total of 120 audience members representing both transplant and LVAD centers, destination therapy only LVAD centers and non-implanting, shared care centers across a multitude of disciplines responded to the survey. Questions comprised of patient selection (body mass index, pre-existing renal failure, care giver presence and abstinence from substance abuse) and patient management (anticoagulation regimens, first line therapy for hemolysis, implantable cardioverter-defibrillator usage and route of preferred dialysis) issues.ConclusionsLVAD technology will continue to change and improve with the next generation of pumps on the horizon. Progress cannot be made without pausing to understand the current state of technology, practice patterns and patient determinants of success. This survey underscores the lack of consensus regarding best practice principles and the need for an increased focus on care management for LVAD patients with collaborative, multi-institutional studies.
      PubDate: Wed, 01 Feb 2017 21:16:10 PST
  • What did we learn about VADs in 2016'

    • Authors: Maya Guglin
      PubDate: Mon, 09 Jan 2017 18:11:07 PST
  • Favorable Outcomes of LVAD as Bridge to Simultaneous Heart-Kidney

    • Authors: Vinay Thohan et al.
      Abstract: BackgroundChronic kidney disease (CKD) is an established risk factor for incident cardiovascular disease and progression of heart failure disease state, and is associated with decreased survival after left ventricular assist device (LVAD) therapy or heart transplantation (HT). Combined heart-kidney transplantation (HKT) compared with isolated HT recently has been shown to have survival advantage among patients whose estimated glomerular filtration rate is less than 37 ml/min/m2. Data on LVAD to HKT are limited.MethodsAt our center, a total of 803 patients have received HT, 594 patients LVAD therapy, and 23 patients HKT from single donors; of those 23, 15 were without the use of LVAD and 8 were after support with LVAD.ResultsKaplan-Meier survival analysis found LVAD-supported patients with CKD stages 4 or 5 had statistically worse 24-month survival after HT as compared with those with CKD stage 1, 2, and 3 (58% vs 88%, p=0.01). Patients who received combined HKT after LVAD had comparable 24-month survival with those who received HKT without LVAD (87% and 85%, p=NS); both groups had numerically better survival compared with those who had CKD (stage 4-5) with isolated HT (58%).ConclusionsPatients supported with LVAD who demonstrate advanced CKD (stage 4-5) have worse 24-month post-HT survival compared with those with less advanced CKD (stage 1-3). Combined HKT after LVAD support is feasible and confers comparable 24-month survival compared with HKT without prior LVAD therapy. Our study supports combined HKT for select LVAD patients with advanced CKD (stage 4-5).
      PubDate: Mon, 05 Dec 2016 17:49:46 PST
  • Fulminant Necrotizing Eosinophilic Myocarditis: A Case Report and
           Comprehensive Literature Review

    • Authors: Bennet George et al.
      Abstract: Acute eosinophilic myocarditis is a relatively rare disorder with serious morbidity and mortality. Due to its infrequency, standardized management guidelines are wanting. We present a case of acute, necrotizing eosinophilic myocarditis requiring several levels of critical care. We reviewed similar cases reported in the literature to highlight common clinical features, describe natural disease course and associated complications, and review varying approaches to medical therapy.
      PubDate: Sat, 05 Nov 2016 12:36:00 PDT
  • Tolerability of Intermittent Hemodialysis in a Cohort of Patients with
           Left Ventricular Assist Device

    • Authors: Christopher Areephanthu et al.
      Abstract: Background: The use of left ventricular assist device (LVAD) has emerged as a popular treatment for patients with advanced heart failure. It is not uncommon for these patients to suffer from renal failure requiring renal replacement therapy. The purpose of this study is to assess hemodynamic parameters and ability to complete the prescribed hemodialysis session in a series of patients who underwent numerous dialysis treatments.Methods: Nine patients with Heart Mate II LVAD received 170 intermittent inpatient hemodialysis treatments between January 1, 2010 and December 31, 2012. Assessment included vital signs, ultrafiltrate removed, hemodialysis duration, symptoms, early terminations (ET), and adverse events during each hemodialysis session.Results: The mean age was 53 ± 18 with a range of 26-83 years, with a male predominance (7/9). Indication for LVAD was as destination therapy (DT) in the majority of patients (6/9). Nine patients who received a total of 170 hemodialysis sessions with a mean prescribed and achieved: ultrafiltration (liters) 1.98 ± 1.5 and 1.90 ± 1.6; hemodialysis duration (hours) 3.12 ± 0.3 and 2.86 ± 0.9, respectively. Early termination was experienced in 11 sessions (6.5%). Causes of ET were hypotension in 72.7%, other causes were equally distributed between clotted extra-corporeal circuits, nausea & vomiting and LVAD alarm (9.1% in each). Serious arrhythmias were not observed in any of the hemodialysis treatments. Six out of nine patients (66.7%) recovered kidney function and became dialysis independent.Conclusion: In a hospital setting, patients with LVAD can often tolerate and complete the prescribed hemodialysis treatment.
      PubDate: Sat, 05 Nov 2016 12:35:55 PDT
  • Fever of Unknown Origin in Patient after Left Ventricular Assist Device

    • Authors: Eugenia Raichlin et al.
      Abstract: Mechanical circulatory support (MCS) is a lifesaving procedure in patients with refractory cardiogenic shock. Despite improvement in surgical techniques, ICU care and restored hemodynamics, some patients on MCS remain severely debilitated due to multiple medical problems, including infections, respiratory failure, de-conditioning and nutritional deficits.Here we present a case of a patient with persistent high degree fever, devastating muscle weakness, and elevated lactate dehydrogenase (LDH) level, who dramatically responded to treatment with vitamin B 12.
      PubDate: Sun, 02 Oct 2016 15:51:07 PDT
  • Adverse Events in Continuous-Flow LVAD Recipients: Gastrointestinal
           Bleeding is Still Notable'

    • Authors: Marija Petrovic et al.
      Abstract: Background: The etiology and risk factors associated with gastrointestinal bleeding (GIB) in patients with continuous-flow left ventricular assist devices (CF-LVADs) are currently unknown. Therefore, we sought to assess the risk factors for GIB in these patients.Design and Methods: This was a retrospective, non-randomized, non-controlled study at a single center. Between 2012 and 2014, 65 men and 6 women (mean age = 55 ± 12 years) underwent CF-LVAD implantation at our institution. Overall, 23.9% of patients (17/71) had at least one GIB episode. Endoscopy confirmed GIB in 13/17. Arteriovenous malformation was the major GIB source in 8/13 (61%). There was no significant difference in incidence of GIB with regard to INTERMACS profile, blood type, or device type—HeartWare vs. HeartMateII. All our patients with GIB were men, most had hyperlipidemia, and most likely had ischemic cardiomyopathy (65%) and peripheral vascular disease (24%). The only significant risk factor for GIB was chronic kidney disease (odds ratio= 3.95; 95% confidence interval of 1.21 to 12.84; p=0.02). At the time of the first GIB, mean hemoglobin was 7.38 ± 1.06 g/dl, international normalized ratio was 2.08 ± 0.69 IU, and mean arterial pressure was 75 ± 12 mmHg. Ten patients (59%) required hospital admission for treatment.Conclusion: In our patients GIB was often a single event and often occurred within first month after implantation. Prevention strategies should be focused on this vulnerable period, especially in patients with chronic kidney disease.
      PubDate: Sun, 02 Oct 2016 15:51:01 PDT
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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