Subjects -> MEDICAL SCIENCES (Total: 8642 journals)
    - ALLERGOLOGY AND IMMUNOLOGY (218 journals)
    - ANAESTHESIOLOGY (120 journals)
    - CARDIOVASCULAR DISEASES (338 journals)
    - CHIROPRACTIC, HOMEOPATHY, OSTEOPATHY (21 journals)
    - COMMUNICABLE DISEASES, EPIDEMIOLOGY (234 journals)
    - DENTISTRY (293 journals)
    - DERMATOLOGY AND VENEREOLOGY (164 journals)
    - EMERGENCY AND INTENSIVE CRITICAL CARE (121 journals)
    - ENDOCRINOLOGY (150 journals)
    - FORENSIC SCIENCES (42 journals)
    - GASTROENTEROLOGY AND HEPATOLOGY (188 journals)
    - GERONTOLOGY AND GERIATRICS (138 journals)
    - HEMATOLOGY (157 journals)
    - HYPNOSIS (4 journals)
    - INTERNAL MEDICINE (174 journals)
    - LABORATORY AND EXPERIMENTAL MEDICINE (99 journals)
    - MEDICAL GENETICS (58 journals)
    - MEDICAL SCIENCES (2392 journals)
    - NURSES AND NURSING (364 journals)
    - OBSTETRICS AND GYNECOLOGY (207 journals)
    - ONCOLOGY (384 journals)
    - OPHTHALMOLOGY AND OPTOMETRY (140 journals)
    - ORTHOPEDICS AND TRAUMATOLOGY (170 journals)
    - OTORHINOLARYNGOLOGY (83 journals)
    - PATHOLOGY (100 journals)
    - PEDIATRICS (275 journals)
    - PHYSICAL MEDICINE AND REHABILITATION (158 journals)
    - PSYCHIATRY AND NEUROLOGY (833 journals)
    - RADIOLOGY AND NUCLEAR MEDICINE (192 journals)
    - RESPIRATORY DISEASES (104 journals)
    - RHEUMATOLOGY (79 journals)
    - SPORTS MEDICINE (81 journals)
    - SURGERY (406 journals)
    - UROLOGY, NEPHROLOGY AND ANDROLOGY (155 journals)

CARDIOVASCULAR DISEASES (338 journals)                  1 2 | Last

Showing 1 - 200 of 338 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 5)
Acta Cardiologica     Hybrid Journal   (Followers: 2)
Acute Cardiac Care     Hybrid Journal   (Followers: 8)
Adipositas - Ursachen, Folgeerkrankungen, Therapie     Hybrid Journal  
AJP Heart and Circulatory Physiology     Hybrid Journal   (Followers: 12)
Aktuelle Kardiologie     Hybrid Journal   (Followers: 1)
American Heart Journal     Hybrid Journal   (Followers: 60)
American Journal of Cardiology     Hybrid Journal   (Followers: 68)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 17)
American Journal of Hypertension     Hybrid Journal   (Followers: 28)
Anales de Cirugia Vascular     Full-text available via subscription   (Followers: 1)
Anatolian Journal of Cardiology     Open Access   (Followers: 6)
Angiología     Full-text available via subscription  
Angiologia e Cirurgia Vascular     Open Access   (Followers: 1)
Angiology     Hybrid Journal   (Followers: 3)
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (Followers: 1)
Annals of Circulation     Open Access   (Followers: 2)
Annals of Noninvasive Electrocardiology     Hybrid Journal   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12)
AORTA     Open Access  
Archives of Cardiovascular Diseases     Full-text available via subscription   (Followers: 5)
Archives of Cardiovascular Diseases Supplements     Full-text available via subscription   (Followers: 3)
Archives of Cardiovascular Imaging     Open Access   (Followers: 2)
Archivos de cardiología de México     Open Access   (Followers: 1)
Argentine Journal of Cardiology (English edition)     Open Access   (Followers: 2)
Arquivos Brasileiros de Cardiologia     Open Access   (Followers: 2)
Arrhythmia & Electrophysiology Review     Open Access   (Followers: 1)
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 32)
Artery Research     Hybrid Journal   (Followers: 4)
ARYA Atherosclerosis     Open Access  
ASAIO Journal     Hybrid Journal   (Followers: 3)
ASEAN Heart Journal     Open Access   (Followers: 2)
Asian Cardiovascular and Thoracic Annals     Hybrid Journal   (Followers: 2)
Aswan Heart Centre Science & Practice Services     Open Access   (Followers: 1)
Atherosclerosis : X     Open Access  
Bangladesh Heart Journal     Open Access   (Followers: 3)
Basic Research in Cardiology     Hybrid Journal   (Followers: 10)
BMC Cardiovascular Disorders     Open Access   (Followers: 22)
Brain Circulation     Open Access   (Followers: 1)
British Journal of Cardiology     Full-text available via subscription   (Followers: 18)
Canadian Journal of Cardiology     Hybrid Journal   (Followers: 18)
Cardiac Cath Lab Director     Full-text available via subscription  
Cardiac Electrophysiology Review     Hybrid Journal   (Followers: 2)
Cardiac Failure Review     Open Access   (Followers: 1)
Cardiocore     Full-text available via subscription   (Followers: 1)
Cardiogenetics     Open Access   (Followers: 3)
Cardiology     Full-text available via subscription   (Followers: 20)
Cardiology and Angiology: An International Journal     Open Access   (Followers: 1)
Cardiology and Therapy     Open Access   (Followers: 12)
Cardiology Clinics     Full-text available via subscription   (Followers: 14)
Cardiology in Review     Hybrid Journal   (Followers: 8)
Cardiology in the Young     Hybrid Journal   (Followers: 34)
Cardiology Journal     Open Access   (Followers: 6)
Cardiology Plus     Open Access   (Followers: 1)
Cardiology Research     Open Access   (Followers: 15)
Cardiology Research and Practice     Open Access   (Followers: 10)
Cardiopulmonary Physical Therapy Journal     Hybrid Journal   (Followers: 8)
Cardiorenal Medicine     Full-text available via subscription   (Followers: 1)
Cardiothoracic Surgeon     Open Access   (Followers: 1)
CardioVasc     Full-text available via subscription   (Followers: 1)
Cardiovascular & Haematological Disorders - Drug Targets     Hybrid Journal   (Followers: 1)
Cardiovascular & Hematological Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 2)
CardioVascular and Interventional Radiology     Hybrid Journal   (Followers: 15)
Cardiovascular and Thoracic Open     Open Access  
Cardiovascular Diabetology     Open Access   (Followers: 10)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 14)
Cardiovascular Endocrinology & Metabolism     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering and Technology     Hybrid Journal   (Followers: 1)
Cardiovascular Intervention and Therapeutics     Hybrid Journal   (Followers: 5)
Cardiovascular Journal     Open Access   (Followers: 6)
Cardiovascular Journal of Africa     Full-text available via subscription   (Followers: 5)
Cardiovascular Journal of South Africa     Full-text available via subscription   (Followers: 1)
Cardiovascular Medicine in General Practice     Full-text available via subscription   (Followers: 7)
Cardiovascular Pathology     Hybrid Journal   (Followers: 4)
Cardiovascular Regenerative Medicine     Open Access  
Cardiovascular Research     Hybrid Journal   (Followers: 15)
Cardiovascular Revascularization Medicine     Hybrid Journal   (Followers: 1)
Cardiovascular System     Open Access  
Cardiovascular Therapeutics     Open Access   (Followers: 1)
Cardiovascular Toxicology     Hybrid Journal   (Followers: 6)
Cardiovascular Ultrasound     Open Access   (Followers: 5)
Case Reports in Cardiology     Open Access   (Followers: 7)
Catheterization and Cardiovascular Interventions     Hybrid Journal   (Followers: 3)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Chest     Full-text available via subscription   (Followers: 103)
Choroby Serca i Naczyń     Open Access   (Followers: 1)
Circulation     Hybrid Journal   (Followers: 265)
Circulation : Cardiovascular Imaging     Hybrid Journal   (Followers: 15)
Circulation : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
Circulation : Cardiovascular Quality and Outcomes     Hybrid Journal   (Followers: 11)
Circulation : Genomic and Precision Medicine     Hybrid Journal   (Followers: 16)
Circulation : Heart Failure     Hybrid Journal   (Followers: 26)
Circulation Research     Hybrid Journal   (Followers: 36)
Cirugía Cardiovascular     Open Access  
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clínica e Investigación en arteriosclerosis (English Edition)     Hybrid Journal  
Clinical and Experimental Hypertension     Hybrid Journal   (Followers: 3)
Clinical Cardiology     Hybrid Journal   (Followers: 11)
Clinical Hypertension     Open Access   (Followers: 5)
Clinical Medicine Insights : Cardiology     Open Access   (Followers: 6)
Clinical Research in Cardiology     Hybrid Journal   (Followers: 6)
Clinical Research in Cardiology Supplements     Hybrid Journal  
Clinical Trials and Regulatory Science in Cardiology     Open Access   (Followers: 4)
Congenital Heart Disease     Hybrid Journal   (Followers: 6)
Congestive Heart Failure     Hybrid Journal   (Followers: 4)
Cor et Vasa     Full-text available via subscription   (Followers: 1)
Coronary Artery Disease     Hybrid Journal   (Followers: 2)
CorSalud     Open Access  
Critical Pathways in Cardiology     Hybrid Journal   (Followers: 4)
Current Cardiology Reports     Hybrid Journal   (Followers: 7)
Current Cardiology Reviews     Hybrid Journal   (Followers: 4)
Current Cardiovascular Imaging Reports     Hybrid Journal   (Followers: 1)
Current Cardiovascular Risk Reports     Hybrid Journal  
Current Heart Failure Reports     Hybrid Journal   (Followers: 5)
Current Hypertension Reports     Hybrid Journal   (Followers: 6)
Current Hypertension Reviews     Hybrid Journal   (Followers: 6)
Current Opinion in Cardiology     Hybrid Journal   (Followers: 14)
Current Problems in Cardiology     Hybrid Journal   (Followers: 3)
Current Research : Cardiology     Full-text available via subscription   (Followers: 1)
Current Treatment Options in Cardiovascular Medicine     Hybrid Journal   (Followers: 1)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 5)
CVIR Endovascular     Open Access   (Followers: 1)
Der Kardiologe     Hybrid Journal   (Followers: 2)
Echo Research and Practice     Open Access   (Followers: 2)
Echocardiography     Hybrid Journal   (Followers: 4)
Egyptian Heart Journal     Open Access   (Followers: 2)
Egyptian Journal of Cardiothoracic Anesthesia     Open Access  
ESC Heart Failure     Open Access   (Followers: 4)
European Cardiology Review     Open Access   (Followers: 1)
European Heart Journal     Hybrid Journal   (Followers: 68)
European Heart Journal - Cardiovascular Imaging     Hybrid Journal   (Followers: 10)
European Heart Journal - Cardiovascular Pharmacotherapy     Full-text available via subscription   (Followers: 2)
European Heart Journal - Quality of Care and Clinical Outcomes     Hybrid Journal  
European Heart Journal : Acute Cardiovascular Care     Hybrid Journal   (Followers: 1)
European Heart Journal : Case Reports     Open Access   (Followers: 1)
European Heart Journal Supplements     Hybrid Journal   (Followers: 8)
European Journal of Cardio-Thoracic Surgery     Hybrid Journal   (Followers: 9)
European Journal of Cardio-Thoracic Surgery Supplements     Full-text available via subscription   (Followers: 2)
European Journal of Cardiovascular Nursing     Hybrid Journal   (Followers: 5)
European Journal of Heart Failure     Hybrid Journal   (Followers: 14)
European Journal of Preventive Cardiology.     Hybrid Journal   (Followers: 6)
European Stroke Organisation     Hybrid Journal   (Followers: 3)
Experimental & Translational Stroke Medicine     Open Access   (Followers: 9)
Expert Review of Cardiovascular Therapy     Full-text available via subscription   (Followers: 3)
Folia Cardiologica     Open Access  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontiers in Cardiovascular Medicine     Open Access   (Followers: 1)
Future Cardiology     Hybrid Journal   (Followers: 6)
General Thoracic and Cardiovascular Surgery     Hybrid Journal   (Followers: 3)
Global Cardiology Science and Practice     Open Access   (Followers: 5)
Global Heart     Hybrid Journal   (Followers: 3)
Heart     Hybrid Journal   (Followers: 48)
Heart and Mind     Open Access  
Heart and Vessels     Hybrid Journal  
Heart Failure Clinics     Full-text available via subscription   (Followers: 2)
Heart Failure Reviews     Hybrid Journal   (Followers: 3)
Heart India     Open Access   (Followers: 2)
Heart International     Full-text available via subscription  
Heart Rhythm     Hybrid Journal   (Followers: 11)
Heart Views     Open Access   (Followers: 2)
HeartRhythm Case Reports     Open Access  
Hellenic Journal of Cardiology     Open Access   (Followers: 1)
Herz     Hybrid Journal   (Followers: 3)
High Blood Pressure & Cardiovascular Prevention     Full-text available via subscription   (Followers: 2)
Hypertension     Full-text available via subscription   (Followers: 23)
Hypertension     Open Access   (Followers: 2)
Hypertension in Pregnancy     Hybrid Journal   (Followers: 9)
Hypertension Research     Hybrid Journal   (Followers: 4)
Ibrahim Cardiac Medical Journal     Open Access  
IJC Heart & Vessels     Open Access   (Followers: 1)
IJC Heart & Vasculature     Open Access   (Followers: 1)
IJC Metabolic & Endocrine     Open Access   (Followers: 1)
Indian Heart Journal     Open Access   (Followers: 5)
Indian Journal of Cardiovascular Disease in Women WINCARS     Open Access  
Indian Journal of Thoracic and Cardiovascular Surgery     Hybrid Journal  
Indian Pacing and Electrophysiology Journal     Open Access   (Followers: 1)
Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery     Hybrid Journal   (Followers: 1)
Insuficiencia Cardíaca     Open Access  
Interactive CardioVascular and Thoracic Surgery     Hybrid Journal   (Followers: 7)
International Cardiovascular Forum Journal     Open Access  
International Journal of Angiology     Hybrid Journal   (Followers: 2)
International Journal of Cardiology     Hybrid Journal   (Followers: 18)
International Journal of Cardiology Hypertension     Open Access   (Followers: 1)
International Journal of Cardiovascular and Cerebrovascular Disease     Open Access   (Followers: 2)
International Journal of Cardiovascular Imaging     Hybrid Journal   (Followers: 2)
International Journal of Cardiovascular Research     Hybrid Journal   (Followers: 6)
International Journal of Heart Rhythm     Open Access  
International Journal of Hypertension     Open Access   (Followers: 8)
International Journal of Hyperthermia     Open Access  
International Journal of Stroke     Hybrid Journal   (Followers: 32)
International Journal of the Cardiovascular Academy     Open Access  
Interventional Cardiology Clinics     Full-text available via subscription   (Followers: 2)
Interventional Cardiology Review     Open Access  
JACC : Basic to Translational Science     Open Access   (Followers: 5)
JACC : Cardiovascular Imaging     Hybrid Journal   (Followers: 18)
JACC : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
JACC : Heart Failure     Full-text available via subscription   (Followers: 14)
JAMA Cardiology     Hybrid Journal   (Followers: 30)

        1 2 | Last

Similar Journals
Journal Cover
Cardiovascular Pathology
Journal Prestige (SJR): 0.885
Citation Impact (citeScore): 2
Number of Followers: 4  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1054-8807 - ISSN (Online) 1879-1336
Published by Elsevier Homepage  [3207 journals]
  • Unusual finding in a cerebral cavernous malformation of the temporal lobe
    • Abstract: Publication date: Available online 28 May 2020Source: Cardiovascular PathologyAuthor(s): Deepti Narasimhaiah, Prakash Nair, Rajalakshmi Poyuran
       
  • Cardiovascular factors predicting poor outcome in COVID – 19
           patients
    • Abstract: Publication date: Available online 28 May 2020Source: Cardiovascular PathologyAuthor(s): Ajay Kumar Mishra, Amos Lal, Kamal Kant Sahu, Jennifer Sargent
       
  • Sudden death by massive systemic embolism from cardiac myxoma. Role of the
           clinical autopsy and review of literature
    • Abstract: Publication date: Available online 23 May 2020Source: Cardiovascular PathologyAuthor(s): Marco Dell'Aquila, Arnaldo Carbone, Ilaria Pennacchia, Egidio Stigliano, Antonio Oliva, Vincenzo Arena
       
  • Hypertrophic cardiomyopathy masquerading as sarcoidosis: cases
           illustrating cardiac imaging overlap relative to pathology
    • Abstract: Publication date: Available online 19 May 2020Source: Cardiovascular PathologyAuthor(s): Stephanie L. Sellers, Jennifer Ellis, Althea Lai, Hannah Salcudean, Anna B. Reid, Philipp Blanke, Bruce M. McManus, Jonathon A. Leipsic, Michael A. Seidman
       
  • Prevention of Heart Failure with Preserved Ejection Fraction (HFpEF):
           Reexamining MicroRNA-21 Inhibition in the Era of Oligonucleotide-Based
           Therapeutics
    • Abstract: Publication date: Available online 19 May 2020Source: Cardiovascular PathologyAuthor(s): David Ben-Nun, L. Maximilian Buja, Francisco Fuentes
       
  • CARDIAC TUMOURS: THREE DECADES OF EXPERIENCE FROM A TERTIARY CENTRE: Are
           we changing diagnostic work-up with new imaging tools'
    • Abstract: Publication date: Available online 18 May 2020Source: Cardiovascular PathologyAuthor(s): Gustavo Sá Mendes, João Abecasis, António Ferreira, Regina Ribeiras, Miguel Abecasis, Rosa Gouveia, Maria João Andrade, Miguel Mendes, Sância Ramos, Carla Saraiva, José Pedro Neves
       
  • Accelerated Miniature Swine Models of Advanced Atherosclerosis: A Review
           Based on Morphology
    • Abstract: Publication date: Available online 16 May 2020Source: Cardiovascular PathologyAuthor(s): Dayang Wang, Xiaoqing Xu, Mingjing Zhao, Xian Wang
       
  • Fatal Pulmonary Thromboembolism in SARS-CoV-2-Infection
    • Abstract: Publication date: September–October 2020Source: Cardiovascular Pathology, Volume 48Author(s):
       
  • THE COMEBACK OF SYPHILITIC AORTITIS
    • Abstract: Publication date: Available online 13 May 2020Source: Cardiovascular PathologyAuthor(s): Andrea De Martino, Uberto Bortolotti, Angela Pucci
       
  • The Effect of Olmesartan on Aortic Intimal Thickening After Balloon Injury
           Through Apelin/APJ
    • Abstract: Publication date: Available online 13 May 2020Source: Cardiovascular PathologyAuthor(s): Yonghong Li, Junjie Guo, Haichu Yu, Jingwei Zhou, Xianming Chu, Bo Hou, Junhua Ge, Tingting Li, Shuo Duan, Hui Xu, Xi Yang
       
  • A Case of Surgically Resected Cardiac Rhabdomyoma with Progressive Left
           Ventricular Outflow Tract Obstruction
    • Abstract: Publication date: Available online 12 May 2020Source: Cardiovascular PathologyAuthor(s): Fazarina Mohammed, Geok Chin Tan, Kan N. Hor, Michael Arnold, Yin Ping Wong
       
  • EMERGING SPECTRUM OF CARDIOPULMONARY PATHOLOGY OF THE CORONAVIRUS DISEASE
           2019 (COVID-19): REPORT OF THREE AUTOPSIES FROM HOUSTON, TEXAS AND REVIEW
           OF AUTOPSY FINDINGS FROM OTHER UNITED STATES CITIES
    • Abstract: Publication date: Available online 7 May 2020Source: Cardiovascular PathologyAuthor(s): L. Maximilian Buja, Dwayne Wolf, Bihong Zhao, Bindu Akkanti, Michelle McDonald, Laura Lelenwa, Noah Reilly, Giulia Ottaviani, M. Tarek Elghetany, Daniel Ocazionez Trujillo, Gabriel M. Aisenberg, Mohammad Madjid, Biswajit Kar
       
  • STEMI During the COVID-19 Pandemic - An Evaluation of Incidence
    • Abstract: Publication date: Available online 1 May 2020Source: Cardiovascular PathologyAuthor(s): Edan Zitelny, Noah Newman, David Zhao
       
  • Morphometric characterisation of collagen and fat in normal ventricular
           myocardium
    • Abstract: Publication date: Available online 1 May 2020Source: Cardiovascular PathologyAuthor(s): Chris Miles, Joseph Westaby, Irina Chis Ster, Angeliki Asimaki, Peter Boardman, Adwait Joshi, Michael Papadakis, Sanjay Sharma, Elijah R. Behr, Mary N. Sheppard
       
  • Saprochaete capitata AORTITIS IN AN IMMUNOCOMOPETENT PATIENT AFTER
           MYOCARDIAL REVASCULARIZATION
    • Abstract: Publication date: Available online 28 April 2020Source: Cardiovascular PathologyAuthor(s): Igor Vendramin, Maddalena Peghin, Elena Graziano, Matteo Bassetti, Chiara Tioni, Dario Sut, Alessandro De Pellegrin, Sandro Sponga, Uberto Bortolotti, Ugolino Livi
       
  • RECURRENT TAKOTSUBO CARDIOMYOPATHY: FURTHER INSIGHTS INTO MORPHOLOGICAL
           PATTERNS
    • Abstract: Publication date: Available online 26 April 2020Source: Cardiovascular PathologyAuthor(s): Kenan Yalta, Ertan Yetkin, Tulin Yalta
       
  • Pathology of Unexpected Sudden Cardiac Death: Obstructive Sleep Apnea is
           Part of the Challenge
    • Abstract: Publication date: Available online 18 April 2020Source: Cardiovascular PathologyAuthor(s): Giulia Ottaviani, L. Maximilian Buja
       
  • Pathophysiological Characteristics and Therapeutic Approaches for
           Pulmonary Injury and Cardiovascular Complications of Coronavirus Disease
           2019
    • Abstract: Publication date: Available online 17 April 2020Source: Cardiovascular PathologyAuthor(s): Yong-Jian Geng, Zhi-Yao Wei, Hai-Yan Qian, Ji Huang, Robert Lodato, Richard J. Castriotta
       
  • OBSTRUCTIVE SLEEP APNEA ANDSUSCEPTIBILITY TO SUDDEN CARDIAC DEATH:A SINGLE
           PLAYER FOR BOTH CONDITIONS'
    • Abstract: Publication date: Available online 15 April 2020Source: Cardiovascular PathologyAuthor(s): Raffaella Mormile
       
  • Commentary from Dr. Bobby Padera regarding Thrombus on the inflow cannula
           of the HeartWare HVAD: an update
    • Abstract: Publication date: Available online 14 March 2020Source: Cardiovascular PathologyAuthor(s): Dr. Bobby Padera
       
  • Cardiovascular Ochronosis
    • Abstract: Publication date: Available online 7 March 2020Source: Cardiovascular PathologyAuthor(s): Nuvaira Ather, William C. Roberts
       
  • Cardiac AA Amyloidosis in a Patient with Obstructive Hypertrophic
           Cardiomyopathy
    • Abstract: Publication date: Available online 7 March 2020Source: Cardiovascular PathologyAuthor(s): Boyangzi Li, Monica Ahluwalia, Navneet Narula, Andre L. Moreira, Daniel G. Swistel, Daniele Massera, Mark V. Sherrid
       
  • Lysosomal storage disorders affecting the heart: a review.
    • Abstract: Publication date: Available online 4 March 2020Source: Cardiovascular PathologyAuthor(s): John P. Veinot, Vidhya Nair
       
  • Immunomodulatory Treatment of Immune Checkpoint Inhibitor-Induced
           Myocarditis: Pathway Toward Precision-Based Therapy
    • Abstract: Publication date: Available online 14 February 2020Source: Cardiovascular PathologyAuthor(s): Dinu Valentin Balanescu, Teodora Donisan, Nicolas Palaskas, Juan Lopez-Mattei, Peter Y. Kim, Louis Maximilian Buja, Dennis M. McNamara, Jon A. Kobashigawa, Jean-Bernard Durand, Cezar A. IliescuAbstractImmune checkpoint inhibitor (ICI)-induced myocarditis carries a poor prognosis and is not fully understood. Similar to lymphocytic myocarditis and acute cellular rejection in heart transplant, ICI-induced myocarditis requires immune suppressive strategies. We aimed to describe ICI-induced myocarditis by presenting findings of comprehensive cardiovascular evaluations and outcomes of patients following a therapeutic approach similar to autoimmune disorders or allograft transplant rejection, and to discuss the molecular basis of the benefits of immune modulation and statins in ICI-myocarditis. Three patients with ICI-induced myocarditis (2 with positive biopsies and 1 based on cardiac magnetic resonance imaging with negative biopsy) underwent a complete cardiovascular workup, including cardiac catheterization with endomyocardial biopsy. Treatment was with intravenous immunoglobulins (IVIG) and statins in all cases, with additional colchicine (2 cases) or hydroxychloroquine (1 case). Immunohistochemical analysis demonstrated varied subsets of T cells involved in the inflammatory response. Therapy with IVIG and statins led to symptom resolution and cardiac function normalization at 1-month follow-up in all patients. Cancer therapy was resumed in all patients. One patient expired 10 months after the myocarditis episode due to advanced malignancy; two patients were alive, free of heart failure symptoms and cancer progression, at 1-year follow-up, and 1 patient was rechallenged with ICI. We suggest that treatment with IVIG and statins may allow for a prompt resumption of anti-cancer therapy (including ICI) and improve outcomes.
       
  • Chemotherapy-associated nonbacterial thrombotic endocarditis: a
           radiological mimicker of cardiac amyloidosis requiring histopathologic
           examination for definitive diagnosis
    • Abstract: Publication date: Available online 11 February 2020Source: Cardiovascular PathologyAuthor(s): Miroslav Sekulic, Amit Gupta, Andrew Patterson, Guilherme Oliveira, Sanjay RajagopalanAbstractNonbacterial thrombotic endocarditis (NBTE) is a form of a thrombotic angiopathy involving the endothelial lined endocardial surfaces of the heart which includes valves and the chamber walls. Underlying etiologies for NBTE include autoimmune diseases, hypercoagulable states, in the setting of certain malignant neoplasms, and physical injury. The pathogenesis for these processes is that of primary endothelial injury resulting in a thrombotic angiopathy. We present a patient being evaluated before a hematopoietic stem cell transplantation with heart failure having previously been provided chemotherapy, and cardiac magnetic resonance imaging (MRI) revealing findings suggestive of amyloidosis. A subsequent endomyocardial biopsy instead showed NBTE characterized by endocardium with fibromyxoid thickening and overlying fresh fibrin. This case highlights histopathologic findings of chemotherapy-associated NBTE involving the right ventricle wall endocardium as well as adding such pathology to the radiological differential in patients with cardiac MRI findings suggestive of amyloidosis.
       
  • Right Sinus of Valsalva Aneurysm
    • Abstract: Publication date: Available online 3 February 2020Source: Cardiovascular PathologyAuthor(s): Giorgia Farì, Ilaria Pennacchia, Egidio Stigliano, Antonio Oliva, Arnaldo Carbone, Vincenzo Arena
       
  • PREVENTION AND MANAGEMENT OF ALLOGRAFT REJECTION IN HEART TRANSPLANTATION:
           ARE miR-126-5p AND miR-126-5p-EXPRESSING MSC-EXOSOMES THE ARIADNE’S
           THREAD'
    • Abstract: Publication date: Available online 1 February 2020Source: Cardiovascular PathologyAuthor(s): Raffaella Mormile
       
  • Mitochondria in aneurysms and dissections of the human ascending aorta
    • Abstract: Publication date: Available online 25 January 2020Source: Cardiovascular PathologyAuthor(s): Paulo Sampaio Gutierrez, Mário Luiz Marques Piubelli, Kalil Georgetto Naal, Ricardo Ribeiro Dias, Luciano Figueiredo BorgesFactors causing the weakness that underlies thoracic aorta aneurysms and dissections are not well known. Based on the findings of apoptosis and ischemic-like necrosis, we hypothesized a possible role for mitochondrial disturbances in the pathogenesis of these diseases. To evaluated if mitochondria at the aortic medial layer are damaged, samples of ascending aortas with aneurysms (n=6), acute dissections (n=5), hypertensive (n=9) and normotensive controls (n=7) were analyzed by transmission electron microscopy. Number of mitochondria, areas of cytoplasm, and areas of mitochondria were measured, and area percentage of the cytoplasm corresponding to mitochondria, their number by unit of area, and their mean area were calculated in randomly taken photographs. Data were compared using one-way ANOVA or Kruskal-Wallis tests. Significant differences (p≤0.05) were found in the number of mitochondria and their mean area, showing opposite results: the number increased and mean area decreased from normotensive controls to hypertensive controls to acute dissections to aneurysms, although post-hoc tests showed that only the differences between the aneurysms and either both controls (number of mitochondria/mm2- 10.37 in normotensive controls, 15.61 in hypertensive controls, and 43.67 in aneurysms) or normotensive controls only (mean area- 2800.15 in normotensive controls vs 894.91μm2 in aneurysms) were significant. In conclusion, there are more, smaller mitochondria in ascending aorta aneurysms. This pattern possibly corresponds to dysfunctional mitochondria, indicating that alterations in the dynamics of these organelles may play a role in the pathogenesis of thoracic aorta aneurysms and dissections.Graphical abstractImage 1
       
  • Isomerism of the Atrial Appendages: Morphology and Terminology
    • Abstract: Publication date: Available online 16 January 2020Source: Cardiovascular PathologyAuthor(s): Carla Frescura, Siew Yen Ho, Gaetano ThieneAbstractBackgroundOur aim is to identify the pathognomonic anatomical markers and the best terminology to describe the cardiac malformations associated with absent or multiple spleens, that are known as asplenia or polysplenia syndromes or isomerism.Materials and methodsWe have reviewed the 65 hearts with isomerism of atrial appendages of the Anatomical Collection of Congenital Heart Disease of the Institute of Pathological Anatomy of the University of Padua consisting in 1800 specimens. All the hearts were classified according to sequential segmental classification.ResultsThe incidence of isomerism was 3,6%. All the 45 hearts with isomerism of right atrial appendages showed bilateral trilobed lungs, short bronchi and absent spleen. The atrioventricular junction was univentricular in 49% of cases with a common atrioventricular valve in 91%. Pulmonary atresia and double outlet right ventricle were present in 40% and 47% of cases respectively. Total anomalous pulmonary venous drainage and absent coronary sinus were always present. In the 20 hearts with isomerism of left atrial appendages, bilateral bilobed lungs with long bilateral bronchi and multiple spleens were always found. Biventricular atrioventricular connection was present in 65% with a common valve in 30% of the hearts. The ventriculo-arterial connection was concordant in 45% of cases and aortic atresia and pulmonary atresia were noted both in 15% of each. An anomalous symmetric pulmonary venous drainage was observed in 65% of the hearts and interruption of inferior vena cava was found in 75% of cases.ConclusionsWe believe that the appropriate terminology is based on the symmetrical morphology of the atrial appendages. The absence of the coronary sinus and the total anomalous pulmonary venous drainage are the markers of isomerism of the right atrial appendages. Symmetric pulmonary venous drainage and interruption of inferior vena cava are the markers of isomerism of left atrial appendages. In recent years, thanks to improvement of clinical diagnosis and of surgical techniques these patients have the possibility to survive to adult age.
       
  • Takotsubo Cardiomyopathy Presenting with Different Morphological Patterns
           in the Same Patient: A case report and review of the literature
    • Abstract: Publication date: Available online 15 January 2020Source: Cardiovascular PathologyAuthor(s): Abdulmohsin Ahmadjee, Khader Herzallah, Yehia Saleh, George S. AbelaAbstractBackgroundTakotsubo Cardiomyopathy is characterized by transient left ventricular systolic dysfunction, which often mimics a myocardial infarction and is usually triggered by emotional or physical stress. There are four variants of Takotsubo Cardiomyopathy, based on the affected left ventricular area.CaseWe report a 75-year-old female with a past medical history of diabetes mellitus, hypertension, hyperlipidemia and chronic kidney disease who presented with chest pain that started after a stressful emotional event. Her electrocardiogram showed no ischemic changes, troponin was mildly elevated and cardiac catheterization revealed non-obstructive coronary artery disease. Echocardiogram showed a decreased ejection fraction and apical akinesia with basal hyperkinesia consistent with classical Takotsubo Cardiomyopathy.Decision-makingThe patient symptomatically improved on optimal heart failure therapy and a follow up echocardiogram showed improvement in her systolic function. Over a year later, the patient was readmitted with chest pain, which also began after an emotional event. ECG showed non-specific ST-T wave changes and troponin was mildly elevated. Echocardiogram demonstrated a reduced ejection fraction and inferior akinesia with apical hyperkinesia consistent with reverse Takotsubo Cardiomyopathy. A repeat cardiac catheterization exhibited mild non-obstructive coronary artery disease unchanged from her previous. A follow up echocardiogram showed full recovery of her systolic function.ConclusionClassical and reverse Takotsubo Cardiomyopathy due to different stressors have been reported in the literature individually, but up to our knowledge, both variants of Takotsubo Cardiomyopathy occurring in the same patient has not been reported previously.
       
  • A Rare Case of Post-Infarction Right Ventricular Rupture
    • Abstract: Publication date: Available online 15 January 2020Source: Cardiovascular PathologyAuthor(s): Samadhi Dandeniyaarachci, Rohan RuwanpuraAbstractA 62-year-old male patient was pronounced dead on admission to the tertiary care hospital. The victim had right ventricular STEMI three years ago. The autopsy showed pericardial tamponade due to rupture of an acute myocardial infarction of the right ventricle.
       
  • Multiple Ulcerations and Perforation in the Small Intestine After Steroid
           Treatment in Eosinophilic Granulomatosis with Polyangiitis: A Case Report
           and Literature Review
    • Abstract: Publication date: Available online 18 December 2019Source: Cardiovascular PathologyAuthor(s): Yukinobu Ito, Makoto Yoshida, Tatsuo Sugiyama, Hirotake Masuda, Mitsuo Mori, Noriyuki Kimura, Michinobu Umakoshi, Ken Miyabe, Yukitsugu Kudo-Asabe, Akiteru GotoAbstractEosinophilic granulomatosis with polyangiitis (EGPA), formerly called Churg-Strauss syndrome, is an uncommon disease with pathological features consisting of systemic necrotizing vasculitis, eosinophilic infiltration, and granulomatous or non-granulomatous extravascular eosinophilic inflammation. EGPA preferentially affects certain organ systems, including the airways, peripheral nerves, heart, kidney, and gastrointestinal tract. Although gastrointestinal involvement, such as ulcerations, is common in EGPA, gastrointestinal perforation is relatively uncommon and is associated with a poor prognosis. Ulceration, perforation, and stenosis of the gastrointestinal tract are assumed to be the result of ischemia caused by vasculitis. The histological findings in the biopsy specimens of EGPA are generally only eosinophil infiltration, and vasculitis is not often seen. Therefore, on biopsy specimens, it is difficult to distinguish eosinophilic gastroenteritis from the gastrointestinal involvement of EGPA. In addition, in general, steroid therapy is the first-choice treatment for EGPA, but some reports have described the frequent occurrence of acute ulcer or perforation of the gastrointestinal tract in association with steroid treatment. We herein report an EGPA patient who was treated with steroid therapy and subsequently developed perforation of the small intestine.
       
 
JournalTOCs
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
Email: journaltocs@hw.ac.uk
Tel: +00 44 (0)131 4513762
 


Your IP address: 3.230.154.129
 
Home (Search)
API
About JournalTOCs
News (blog, publications)
JournalTOCs on Twitter   JournalTOCs on Facebook

JournalTOCs © 2009-