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CARDIOVASCULAR DISEASES (339 journals)                  1 2 | Last

Showing 1 - 200 of 339 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 5)
Acta Cardiologica     Hybrid Journal   (Followers: 2)
Acute Cardiac Care     Hybrid Journal   (Followers: 9)
Adipositas - Ursachen, Folgeerkrankungen, Therapie     Hybrid Journal  
AJP Heart and Circulatory Physiology     Hybrid Journal   (Followers: 12)
Aktuelle Kardiologie     Hybrid Journal   (Followers: 2)
American Heart Journal     Hybrid Journal   (Followers: 64)
American Journal of Cardiology     Hybrid Journal   (Followers: 72)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 21)
American Journal of Hypertension     Hybrid Journal   (Followers: 29)
Anales de Cirugia Vascular     Full-text available via subscription   (Followers: 1)
Anatolian Journal of Cardiology     Open Access   (Followers: 6)
Angiología     Full-text available via subscription  
Angiologia e Cirurgia Vascular     Open Access   (Followers: 1)
Angiology     Hybrid Journal   (Followers: 3)
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (Followers: 1)
Annals of Circulation     Open Access   (Followers: 2)
Annals of Noninvasive Electrocardiology     Hybrid Journal   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12)
AORTA     Open Access  
Archives of Cardiovascular Diseases     Full-text available via subscription   (Followers: 6)
Archives of Cardiovascular Diseases Supplements     Full-text available via subscription   (Followers: 4)
Archives of Cardiovascular Imaging     Open Access   (Followers: 2)
Archivos de cardiología de México     Open Access   (Followers: 1)
Argentine Journal of Cardiology (English edition)     Open Access   (Followers: 3)
Arquivos Brasileiros de Cardiologia     Open Access   (Followers: 2)
Arrhythmia & Electrophysiology Review     Open Access   (Followers: 1)
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 34)
Artery Research     Hybrid Journal   (Followers: 5)
ARYA Atherosclerosis     Open Access  
ASAIO Journal     Hybrid Journal   (Followers: 4)
ASEAN Heart Journal     Open Access   (Followers: 3)
Asian Cardiovascular and Thoracic Annals     Hybrid Journal   (Followers: 2)
Aswan Heart Centre Science & Practice Services     Open Access   (Followers: 1)
Atherosclerosis : X     Open Access  
Bangladesh Heart Journal     Open Access   (Followers: 3)
Basic Research in Cardiology     Hybrid Journal   (Followers: 10)
BMC Cardiovascular Disorders     Open Access   (Followers: 25)
Brain Circulation     Open Access   (Followers: 1)
British Journal of Cardiology     Full-text available via subscription   (Followers: 18)
Canadian Journal of Cardiology     Hybrid Journal   (Followers: 18)
Cardiac Cath Lab Director     Full-text available via subscription  
Cardiac Electrophysiology Review     Hybrid Journal   (Followers: 2)
Cardiac Failure Review     Open Access   (Followers: 2)
Cardiocore     Full-text available via subscription   (Followers: 1)
Cardiogenetics     Open Access   (Followers: 4)
Cardiology     Full-text available via subscription   (Followers: 20)
Cardiology and Angiology: An International Journal     Open Access   (Followers: 1)
Cardiology and Therapy     Open Access   (Followers: 11)
Cardiology Clinics     Full-text available via subscription   (Followers: 14)
Cardiology in Review     Hybrid Journal   (Followers: 9)
Cardiology in the Young     Hybrid Journal   (Followers: 35)
Cardiology Journal     Open Access   (Followers: 6)
Cardiology Plus     Open Access   (Followers: 1)
Cardiology Research     Open Access   (Followers: 15)
Cardiology Research and Practice     Open Access   (Followers: 11)
Cardiopulmonary Physical Therapy Journal     Hybrid Journal   (Followers: 9)
Cardiorenal Medicine     Full-text available via subscription   (Followers: 1)
Cardiothoracic Surgeon     Open Access   (Followers: 2)
CardioVasc     Full-text available via subscription   (Followers: 1)
Cardiovascular & Haematological Disorders - Drug Targets     Hybrid Journal   (Followers: 2)
Cardiovascular & Hematological Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 2)
CardioVascular and Interventional Radiology     Hybrid Journal   (Followers: 15)
Cardiovascular and Thoracic Open     Open Access  
Cardiovascular Diabetology     Open Access   (Followers: 10)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 16)
Cardiovascular Endocrinology & Metabolism     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering     Hybrid Journal   (Followers: 2)
Cardiovascular Engineering and Technology     Hybrid Journal   (Followers: 2)
Cardiovascular Intervention and Therapeutics     Hybrid Journal   (Followers: 6)
Cardiovascular Journal     Open Access   (Followers: 7)
Cardiovascular Journal of Africa     Full-text available via subscription   (Followers: 5)
Cardiovascular Journal of South Africa     Full-text available via subscription   (Followers: 2)
Cardiovascular Medicine in General Practice     Full-text available via subscription   (Followers: 7)
Cardiovascular Pathology     Hybrid Journal   (Followers: 4)
Cardiovascular Regenerative Medicine     Open Access  
Cardiovascular Research     Hybrid Journal   (Followers: 17)
Cardiovascular Revascularization Medicine     Hybrid Journal   (Followers: 1)
Cardiovascular System     Open Access  
Cardiovascular Therapeutics     Open Access   (Followers: 2)
Cardiovascular Toxicology     Hybrid Journal   (Followers: 8)
Cardiovascular Ultrasound     Open Access   (Followers: 5)
Case Reports in Cardiology     Open Access   (Followers: 8)
Catheterization and Cardiovascular Interventions     Hybrid Journal   (Followers: 4)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Chest     Full-text available via subscription   (Followers: 112)
Choroby Serca i Naczyń     Open Access   (Followers: 1)
Circulation     Hybrid Journal   (Followers: 284)
Circulation : Cardiovascular Imaging     Hybrid Journal   (Followers: 17)
Circulation : Cardiovascular Interventions     Hybrid Journal   (Followers: 20)
Circulation : Cardiovascular Quality and Outcomes     Hybrid Journal   (Followers: 13)
Circulation : Genomic and Precision Medicine     Hybrid Journal   (Followers: 17)
Circulation : Heart Failure     Hybrid Journal   (Followers: 32)
Circulation Research     Hybrid Journal   (Followers: 36)
Cirugía Cardiovascular     Open Access  
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clínica e Investigación en arteriosclerosis (English Edition)     Hybrid Journal  
Clinical and Experimental Hypertension     Hybrid Journal   (Followers: 3)
Clinical Cardiology     Hybrid Journal   (Followers: 10)
Clinical Hypertension     Open Access   (Followers: 5)
Clinical Medicine Insights : Cardiology     Open Access   (Followers: 6)
Clinical Research in Cardiology     Hybrid Journal   (Followers: 5)
Clinical Research in Cardiology Supplements     Hybrid Journal  
Clinical Trials and Regulatory Science in Cardiology     Open Access   (Followers: 4)
Congenital Heart Disease     Hybrid Journal   (Followers: 7)
Congestive Heart Failure     Hybrid Journal   (Followers: 4)
Cor et Vasa     Full-text available via subscription   (Followers: 2)
Coronary Artery Disease     Hybrid Journal   (Followers: 3)
CorSalud     Open Access  
Critical Pathways in Cardiology     Hybrid Journal   (Followers: 5)
Current Cardiology Reports     Hybrid Journal   (Followers: 6)
Current Cardiology Reviews     Hybrid Journal   (Followers: 3)
Current Cardiovascular Imaging Reports     Hybrid Journal   (Followers: 1)
Current Cardiovascular Risk Reports     Hybrid Journal  
Current Heart Failure Reports     Hybrid Journal   (Followers: 5)
Current Hypertension Reports     Hybrid Journal   (Followers: 6)
Current Hypertension Reviews     Hybrid Journal   (Followers: 6)
Current Opinion in Cardiology     Hybrid Journal   (Followers: 13)
Current Problems in Cardiology     Hybrid Journal   (Followers: 3)
Current Research : Cardiology     Full-text available via subscription   (Followers: 1)
Current Treatment Options in Cardiovascular Medicine     Hybrid Journal   (Followers: 3)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 5)
CVIR Endovascular     Open Access   (Followers: 1)
Der Kardiologe     Hybrid Journal   (Followers: 1)
Echo Research and Practice     Open Access   (Followers: 2)
Echocardiography     Hybrid Journal   (Followers: 4)
Egyptian Heart Journal     Open Access   (Followers: 2)
Egyptian Journal of Cardiothoracic Anesthesia     Open Access  
ESC Heart Failure     Open Access   (Followers: 4)
European Cardiology Review     Open Access   (Followers: 1)
European Heart Journal     Hybrid Journal   (Followers: 73)
European Heart Journal - Cardiovascular Imaging     Hybrid Journal   (Followers: 11)
European Heart Journal - Cardiovascular Pharmacotherapy     Full-text available via subscription   (Followers: 2)
European Heart Journal - Quality of Care and Clinical Outcomes     Hybrid Journal  
European Heart Journal : Acute Cardiovascular Care     Hybrid Journal   (Followers: 1)
European Heart Journal : Case Reports     Open Access   (Followers: 2)
European Heart Journal Supplements     Hybrid Journal   (Followers: 7)
European Journal of Cardio-Thoracic Surgery     Hybrid Journal   (Followers: 9)
European Journal of Cardio-Thoracic Surgery Supplements     Full-text available via subscription   (Followers: 2)
European Journal of Cardiovascular Nursing     Hybrid Journal   (Followers: 5)
European Journal of Heart Failure     Hybrid Journal   (Followers: 14)
European Journal of Preventive Cardiology.     Hybrid Journal   (Followers: 6)
European Stroke Organisation     Hybrid Journal   (Followers: 3)
Experimental & Translational Stroke Medicine     Open Access   (Followers: 10)
Expert Review of Cardiovascular Therapy     Full-text available via subscription   (Followers: 4)
Folia Cardiologica     Open Access  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontiers in Cardiovascular Medicine     Open Access   (Followers: 1)
Future Cardiology     Hybrid Journal   (Followers: 5)
General Thoracic and Cardiovascular Surgery     Hybrid Journal   (Followers: 4)
Global Cardiology Science and Practice     Open Access   (Followers: 5)
Global Heart     Hybrid Journal   (Followers: 3)
Heart     Hybrid Journal   (Followers: 52)
Heart and Mind     Open Access  
Heart and Vessels     Hybrid Journal  
Heart Failure Clinics     Full-text available via subscription   (Followers: 3)
Heart Failure Reviews     Hybrid Journal   (Followers: 3)
Heart India     Open Access   (Followers: 2)
Heart International     Full-text available via subscription  
Heart Rhythm     Hybrid Journal   (Followers: 12)
Heart Views     Open Access   (Followers: 2)
HeartRhythm Case Reports     Open Access  
Hearts     Open Access   (Followers: 2)
Hellenic Journal of Cardiology     Open Access   (Followers: 1)
Herz     Hybrid Journal   (Followers: 2)
High Blood Pressure & Cardiovascular Prevention     Full-text available via subscription   (Followers: 3)
Hypertension     Full-text available via subscription   (Followers: 24)
Hypertension     Open Access   (Followers: 2)
Hypertension in Pregnancy     Hybrid Journal   (Followers: 9)
Hypertension Research     Hybrid Journal   (Followers: 4)
Ibrahim Cardiac Medical Journal     Open Access  
IJC Heart & Vessels     Open Access   (Followers: 1)
IJC Heart & Vasculature     Open Access   (Followers: 1)
IJC Metabolic & Endocrine     Open Access   (Followers: 1)
Indian Heart Journal     Open Access   (Followers: 5)
Indian Journal of Cardiovascular Disease in Women WINCARS     Open Access  
Indian Journal of Thoracic and Cardiovascular Surgery     Hybrid Journal  
Indian Pacing and Electrophysiology Journal     Open Access   (Followers: 1)
Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery     Hybrid Journal   (Followers: 2)
Insuficiencia Cardíaca     Open Access  
Interactive CardioVascular and Thoracic Surgery     Hybrid Journal   (Followers: 7)
International Cardiovascular Forum Journal     Open Access  
International Journal of Angiology     Hybrid Journal  
International Journal of Cardiology     Hybrid Journal   (Followers: 17)
International Journal of Cardiology Hypertension     Open Access   (Followers: 1)
International Journal of Cardiovascular and Cerebrovascular Disease     Open Access   (Followers: 3)
International Journal of Cardiovascular Imaging     Hybrid Journal   (Followers: 2)
International Journal of Cardiovascular Research     Hybrid Journal   (Followers: 6)
International Journal of Heart Rhythm     Open Access  
International Journal of Hypertension     Open Access   (Followers: 8)
International Journal of Hyperthermia     Open Access  
International Journal of Stroke     Hybrid Journal   (Followers: 33)
International Journal of the Cardiovascular Academy     Open Access  
Interventional Cardiology Clinics     Full-text available via subscription   (Followers: 2)
Interventional Cardiology Review     Open Access  
JACC : Basic to Translational Science     Open Access   (Followers: 6)
JACC : Cardiovascular Imaging     Hybrid Journal   (Followers: 22)
JACC : Cardiovascular Interventions     Hybrid Journal   (Followers: 23)
JACC : Heart Failure     Full-text available via subscription   (Followers: 18)

        1 2 | Last

Similar Journals
Journal Cover
Circulation : Cardiovascular Imaging
Journal Prestige (SJR): 3.242
Citation Impact (citeScore): 4
Number of Followers: 17  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1941-9651 - ISSN (Online) 1942-0080
Published by American Heart Association Homepage  [12 journals]
  • Spatially Weighted Coronary Artery Calcium Score and Coronary Heart
           Disease Events in the Multi-Ethnic Study of Atherosclerosis
    • Authors: Steven Shea Ana Navas-Acien Daichi Shimbo Elizabeth R. Brown Matthew Budoff Michael P. Bancks R. Graham Barr Richard Kronmal Department of Medicine; Vagelos College of Physicians Prevention, Wake Forest School of Medicine, Winston-Salem, NC (M.P.B.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.
      Background:A limitation of the Agatston coronary artery calcium (CAC) score is that it does not use all of the calcium density information in the computed tomography scan such that many individuals have a score of zero. We examined the predictive validity for incident coronary heart disease (CHD) events of the spatially weighted coronary calcium score (SWCS), an alternative scoring method for CAC that assigns scores to individuals with Agatston CAC=0.Methods:The MESA (Multi-Ethnic Study of Atherosclerosis) is a longitudinal study that conducted a baseline exam from 2000 to 2002 in 6814 participants including computed tomography scanning for CAC. Subsequent exams and systematic follow-up of the cohort for outcomes were performed. Statistical models were adjusted using the MESA risk score based on age, sex, race/ethnicity, systolic blood pressure, use of hypertension medications, diabetes, total and HDL (high-density lipoprotein) cholesterol, use of lipid-lowering medications, smoking status, and family history of heart attack.Results:In the 3286 participants with Agatston CAC=0 at baseline and for whom SWCS was computed, 98 incident CHD events defined as definite or probably myocardial infarction or definite CHD death occurred during a median follow-up of 15.1 years. In this group, SWCS predicted incident CHD events after multivariable adjustment (hazard ratio=1.30 per SD of natural logarithm [SWCS] [95% CI, 1.04–1.60];P=0.005); and progression from Agatston CAC=0 at baseline to CAC>0 at subsequent exams (multivariable-adjusted incidence rate difference per SD of natural logarithm [SWCS] per 100 person-years 1.68 [95% CI, 1.03–2.33];P<0.0001).Conclusions:SWCS predicts incident CHD events in individuals with Agatston CAC score=0 as well as conversion to Agatston CAC>0 at repeat computed tomography scanning at later exams. SWCS has predictive validity as a subclinical phenotype and marker of CHD risk in individuals with Agatston CAC=0.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:56Z
      DOI: 10.1161/CIRCIMAGING.120.011981
      Issue No: Vol. 14, No. 1 (2021)
       
  • Higher Acceleration/Ejection Time Ratio Predicts Impaired Outcome in
           Aortic Valve Stenosis
    • Authors: Eigir Einarsen Dana Cramariuc Edda Bahlmann Helga Midtbo John B. Chambers Eva Gerdts Department of Clinical Science; University of Bergen, Norway (E.E., E.G.). Department of Heart Disease, Haukeland University Hospital, Bergen, Norway (D.C., H.M., E.G.). Department of Cardiology, Asklepios Clinic St. Georg, Hamburg, Germany (E.B.). Cardiothoracic Centre, Guys St. Thomas Hospitals, London, United Kingdom (J.B.C.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.
      Background:Acceleration time (AT)/ejection time (ET) ratio is a marker of aortic valve stenosis (AS) severity and predicts outcome in moderate-severe AS.Methods:We explored the association of increased AT/ET ratio on prognosis in 1530 asymptomatic patients with presumably mild-moderate AS, normal ejection fraction, and without known diabetes or cardiovascular disease. Patients were part of the SEAS study (Simvastatin Ezetimibe Aortic Stenosis). Patients were grouped according to the optimal AT/ET ratio threshold to predict cardiovascular death and heart failure hospitalization. Low-gradient severe AS was identified as combined valve area ≤1.0 cm2and mean gradient <40 mm Hg. Outcome was assessed in Cox regression analyses, and results are reported as hazard ratio and 95% CI.Results:Higher AT/ET ratio was significantly associated with lower systolic blood pressure, lower left ventricular ejection fraction, lower stress-corrected midwall shortening, low flow, and with higher left ventricular mass and higher peak aortic jet velocity. AT/ET ratio ≥0.32 provided the optimal cutoff for predicting incident cardiovascular death and heart failure hospitalization in the total study sample. In patients with low-gradient severe AS, this threshold was >0.32. AT/ET ratio ≥0.32 had a 79% higher risk of cardiovascular death and heart failure hospitalization (hazard ratio, 1.79 [95% CI, 1.20–2.68]). In patients with low-gradient severe AS, AT/ET ratio >0.32 was associated with a 2-fold higher risk of cardiovascular death and heart failure hospitalization (hazard ratio, 2.15 [95% CI, 1.22–3.77]).Conclusions:In asymptomatic nonsevere AS and low-gradient severe AS, higher AT/ET ratio was associated with increased cardiovascular morbidity and mortality.Registration:URL:https://www.clinicaltrials.gov; Unique identifier: NCT00092677.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:45Z
      DOI: 10.1161/CIRCIMAGING.120.011467
      Issue No: Vol. 14, No. 1 (2021)
       
  • Spatially Weighted Calcium Score Beyond Power of Zero
    • Authors: Marcio Sommer Bittencourt Khurram Nasir Center for Clinical; Vascular Center, Houston, TX (K.N.). Center for Outcomes Research, The Houston Methodist Research Institute, Houston, TX (K.N.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:34Z
      DOI: 10.1161/CIRCIMAGING.120.012236
      Issue No: Vol. 14, No. 1 (2021)
       
  • Building Experience and Evidence
    • Authors: Amanda K. Verma Justin M. Vader Section of Heart Failure; Cardiac Transplantation, Cardiovascular Division, Department of Medicine, Washington University School of Medicine, St. Louis, MO.
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:33Z
      DOI: 10.1161/CIRCIMAGING.120.012220
      Issue No: Vol. 14, No. 1 (2021)
       
  • Left Atrial Volumetric/Mechanical Coupling Index
    • Authors: Giovanni Benfari Benjamin Essayagh Stefano Nistri Joseph Maalouf Andrea Rossi Prabin Thapa Hector I. Michelena Maurice Enriquez-Sarano Department of Cardiovascular Diseases, Mayo Clinic, Mayo Clinic, Rochester, MN (G.B; B.E, J.M, P.T, H.I.M, M.E.-S.). University of Verona, Section of Cardiology, Department of Medicine, Italy (G.B, A.R.). CMSR Veneto Medica, Cardiology Service, Altavilla Vicentina, Vicenza, Italy (S.N.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.
      Background:Left atrial assessment is complex, particularly in heart failure with reduced ejection fraction due to interactions with functional mitral regurgitation (FMR). Pilot data suggest that left atrial volumetric/mechanical coupling index (LACI) may be useful, but large outcome data are lacking.Methods:We enrolled a comprehensively characterized cohort of patients in sinus rhythm with heart failure with reduced ejection fraction diagnosis at Mayo Clinic from 2007 to 2011. Routinely measured left atrial volume index and tissue-doppler-imaging a’ allowed LACI calculation as (left atrial volume index)/(tissue-doppler-imaging a’). Survival was the outcome measured.Results:The cohort’s 4196 patients (69 [58–77] years, ejection fraction 40 [31–45]%) had mild FMR in 1505 and moderate-severe FMR in 1068. LACI was overall 5.06 (3.50–8.10) and increased with each FMR grade (3.86 [2.94–5.29] without FMR, 5.38 [3.80–8.02] with mild, 5.45 [1.49–8.07] with moderate/severe FMR;P<0.0001). At diagnosis, higher LACI was independently determined by more severe FMR and by higher left ventricular mass index, lower ejection fraction, higher E/e’, and lower glomerular filtration rate (allP<0.0001). During follow-up 1588 (38%) patients died. In spline modeling, excess mortality appeared around LACI=6 and steeply increased thereafter (5-year survival 72±1% with LACI<6 and 49±2% with LACI ≥6,P<0.0001). Multivariable comprehensive adjustment showed LACI strong association with excess mortality (adjusted hazard ratio, 1.41 [1.23–1.61],P<0.0001 for LACI ≥6). Independent link to mortality persistent across FMR grades (adjusted hazard ratio, 1.45 [1.13–1.86],P=0.004 without FMR, 1.42 [1.16–1.77],P=0.0008 with mild FMR, and 1.38 [1.01–1.66],P=0.04 with moderate/severe FMR) without interaction (P=0.3). LACI independent impact on outcome was incremental to that of left atrial volume index, tissue-doppler-imaging a’, or any other characteristic including the Meta-Analysis Global Group in Chronic-score (least significantP=0.02).Conclusions:In this large cohort, left atrial volumetric/mechanical coupling measured by LACI in routine practice integrates the influence of several morphological/hemodynamic determinants but displays progressive deterioration with increasing FMR severity in heart failure with reduced ejection fraction. About outcome, higher LACI is strongly, independently, and incrementally associated with excess mortality, irrespective of FMR grade and in all subsets. Hence, LACI is a novel and critical measure in heart failure with reduced ejection fraction, quantifiable in routine practice, which should be integrated in prognostication and decision-making.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:06Z
      DOI: 10.1161/CIRCIMAGING.120.011608
      Issue No: Vol. 14, No. 1 (2021)
       
  • Myocardial Inflammation and Dysfunction in COVID-19–Associated
           Myocardial Injury
    • Authors: Ludwig T. Weckbach Adrian Curta Stephanie Bieber Angelina Kraechan Johannes Brado Johannes C. Hellmuth Maximilian Muenchhoff Clemens Scherer Ines Schroeder Michael Irlbeck Stefan Maurus Jens Ricke Karin Klingel Stefan Kääb Mathias Orban Steffen Massberg Jörg Hausleiter Ulrich Grabmaier Medical Department I (L.T.W.; S.B., A.K., J.B., C.S., S.K., M.O., S. Massberg, J.H., U.G.), Ludwig-Maximilians-University, Munich, Germany. Department of Radiology (A.C., S. Maurus, J.R.), Ludwig-Maximilians-University, Munich, Germany. Medical Department III (J.C.H.), Ludwig-Maximilians-University, Munich, Germany. Department of Anaesthesiology (I.S., M.I.), Ludwig-Maximilians-University, Munich, Germany. Institute of Cardiovascular Physiology Neuropathology, University Hospital Tuebingen, Germany (K.K.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.
      Background:Myocardial injury, defined by elevated troponin levels, is associated with adverse outcome in patients with coronavirus disease 2019 (COVID-19). The frequency of cardiac injury remains highly uncertain and confounded in current publications; myocarditis is one of several mechanisms that have been proposed.Methods:We prospectively assessed patients with myocardial injury hospitalized for COVID-19 using transthoracic echocardiography, cardiac magnetic resonance imaging, and endomyocardial biopsy.Results:Eighteen patients with COVID-19 and myocardial injury were included in this study. Echocardiography revealed normal to mildly reduced left ventricular ejection fraction of 52.5% (46.5%–60.5%) but moderately to severely reduced left ventricular global longitudinal strain of −11.2% (−7.6% to −15.1%). Cardiac magnetic resonance showed any myocardial tissue injury defined by elevated T1, extracellular volume, or late gadolinium enhancement with a nonischemic pattern in 16 patients (83.3%). Seven patients (38.9%) demonstrated myocardial edema in addition to tissue injury fulfilling the Lake-Louise criteria for myocarditis. Combining cardiac magnetic resonance with speckle tracking echocardiography demonstrated functional or morphological cardiac changes in 100% of investigated patients. Endomyocardial biopsy was conducted in 5 patients and revealed enhanced macrophage numbers in all 5 patients in addition to lymphocytic myocarditis in 1 patient. SARS-CoV-2 RNA was not detected in any biopsy by quantitative real-time polymerase chain reaction. Finally, follow-up measurements of left ventricular global longitudinal strain revealed significant improvement after a median of 52.0 days (−11.2% [−9.2% to −14.7%] versus −15.6% [−12.5% to −19.6%] at follow-up;P=0.041).Conclusions:In this small cohort of COVID-19 patients with elevated troponin levels, myocardial injury was evidenced by reduced echocardiographic left ventricular strain, myocarditis patterns on cardiac magnetic resonance, and enhanced macrophage numbers but not predominantly lymphocytic myocarditis in endomyocardial biopsies.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:05Z
      DOI: 10.1161/CIRCIMAGING.120.011713
      Issue No: Vol. 14, No. 1 (2021)
       
  • Left Atrial Coupling Index and Its Prognostic Value in Heart Failure With
           Reduced Ejection Fraction
    • Authors: Mahesh K. Vidula Julio A. Chirinos Division of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA (M.K.V; J.A.C.). University of Pennsylvania Perelman School of Medicine, Philadelphia, PA (J.A.C.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:05Z
      DOI: 10.1161/CIRCIMAGING.120.012221
      Issue No: Vol. 14, No. 1 (2021)
       
  • Acceleration Time in Aortic Stenosis
    • Authors: Sylvestre Maréchaux Christophe Tribouilloy Groupement des Hôpitaux de l’Institut Catholique de Lille, Department of Cardiology, Lille Catholic University, France (S.M.). Department of Cardiology, Amiens University Hospital, France (C.T.). UR UPJV 7517, Jules Verne University of Picardie, Amiens, France (S.M; C.T.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-19T10:00:03Z
      DOI: 10.1161/CIRCIMAGING.120.012234
      Issue No: Vol. 14, No. 1 (2021)
       
  • Left Circumflex Artery-Left Atria Fistula Treated With Transcatheter
           Closure
    • Authors: Xiao-Feng Zhuang Jing Ping Sun Zhi-Hui Hou Mu-Zi Li Xiao-Lu Sun Department of Cardiology (X.-F.Z.; J.P.S., X.-L.S.), National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences Peking Union Medical College, Fuwai Hospital, China.
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-18T10:00:39Z
      DOI: 10.1161/CIRCIMAGING.120.010913
      Issue No: Vol. 14, No. 1 (2021)
       
  • Myocardial Ischemia in the Management of Chronic Coronary Artery Disease
    • Authors: Raymond J. Gibbons Department of Cardiovascular Medicine; Mayo Clinic, Rochester, MN.
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.
      For many years, stress-induced myocardial ischemia has been considered important in the management of chronic coronary artery disease. Early evidence focused on the exercise ECG and the Duke treadmill score. In the 1970s, randomized clinical trials, which compared coronary artery bypass surgery to medical therapy, enrolled patients who were very different from contemporary practice and had inconsistent results. Surgery appeared to be of greatest benefit in high-risk patients defined by anatomy (such as left main disease) or stress-induced ischemia. However, randomized clinical trials of revascularization versus contemporary medical therapy over the past 20 years have been surprisingly negative. Nuclear cardiology substudies from these trials reported inconsistent results. Two observational studies from a single-center provided the best evidence for the use of stress-induced ischemia to identify patients who were most likely to benefit from revascularization. The recently completed ISCHEMIA trial (International Study of Comparative Health Effectiveness With Medical and Invasive Approaches) was designed to test the hypothesis that revascularization would improve outcomes in patients with moderate-severe ischemia on stress testing. Unfortunately, 14.2% of the randomized patients had either mild or no ischemia on core lab review. Nearly one-quarter of the patients were randomized on the basis of an exercise ECG without imaging. The negative results of the trial reflect the long-term population decline in coronary artery disease and abnormal stress tests, as well as improvements in patient outcome due to optimal medical therapy. Topics requiring further research are presented. The implications of the trial for the use of both stress imaging and coronary computed tomography angiography in clinical practice are examined.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-18T10:00:24Z
      DOI: 10.1161/CIRCIMAGING.120.011615
      Issue No: Vol. 14, No. 1 (2021)
       
  • ISCHEMIA Trial
    • Authors: Rory Hachamovitch Prem Soman Cardiovascular Imaging Section; Department of Cardiovascular Medicine, Heart Vascular Institute, Cleveland Clinic Foundation, OH (R.H.). University of Pittsburgh, PA (P.S.).
      Abstract: Circulation: Cardiovascular Imaging, Volume 14, Issue 1, January 1, 2021.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-18T10:00:02Z
      DOI: 10.1161/CIRCIMAGING.120.012319
      Issue No: Vol. 14, No. 1 (2021)
       
  • Prognostic Impact of Late Gadolinium Enhancement by Cardiovascular
           Magnetic Resonance in Myocarditis
    • Authors: Georgios Georgiopoulos Stefano Figliozzi Francesca Sanguineti Giovanni Donato Aquaro Gianluca di Bella Kimon Stamatelopoulos Amedeo Chiribiri Jerome Garot Pier Giorgio Masci Tevfik F. Ismail School of Biomedical Engineering & Imaging Sciences; King’s College London, United Kingdom (G.G., S.F., A.C., P.G.M., T.F.I.). Department of Clinical Therapeutics, National Pharmacology, University of Messina, Italy (G.d.B.).
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.
      BackgroundPatients with acute myocarditis (AM) are at increased risk of adverse cardiac events after the index episode. Late gadolinium enhancement (LGE) detected by cardiovascular magnetic resonance in patients with AM plays an important diagnostic role, but its prognostic significance remains unresolved. This systematic review and meta-analysis sought to assess the prognostic implications of cardiovascular magnetic resonance-derived LGE in patients with AM.MethodsData search was conducted from inception through February 28, 2020, using the following Medical Subject Heading terms:Myocarditis, CMR, Magnetic Resonance Imaging, Magnetic Resonance. From 2422 articles retrieved, we selected 11 studies reporting baseline cardiovascular magnetic resonance assessment and long-term clinical follow-up in patients with AM. Hazard ratios and CIs for a combined clinical end point were recorded for LGE presence, extent (>2 segments or >10% of left ventricular [LV] mass or >17g) and location (anteroseptal versus non-anteroseptal). A combined end point comprised all-cause mortality, cardiac mortality, and major adverse cardiovascular events. Hartung and Knapp correction improved robustness of the results. Prespecified sensitivity analyses explored potential sources of heterogeneity. The meta-analysis was conducted according to the Meta-analysis of Observational Studies in Epidemiology guidelines.ResultsLGE presence (pooled hazard ratios, 3.28 [95% CIs, 1.69–6.39],P<0.001 [95% CIs, 1.33–8.11] after Hartung and Knapp correction) and anteroseptal LGE (pooled-hazard ratios, 2.58 [95% CIs, 1.87–3.55],P<0.001 [95% CIs, 1.64–4.06] after Hartung and Knapp correction) were associated with an increased risk of the combined end point. Extensive LGE was associated with worse outcomes (pooled-hazard ratios, 1.96 [95% CIs, 1.08–3.56],P=0.027), but this association was not confirmed after Hartung and Knapp correction (95% CIs, 0.843–4.57).ConclusionsLGE presence and anteroseptal location at baseline cardiovascular magnetic resonance are important independent prognostic markers that herald an increased risk of adverse cardiac outcomes in patients with AM.REGISTRATION:https://www.crd.york.ac.uk/PROSPERO/Unique identifier: CRD42019146619.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-14T10:00:02Z
      DOI: 10.1161/CIRCIMAGING.120.011492
       
  • Prognostic Value of Pulmonary Transit Time by Cardiac Magnetic Resonance
           on Mortality and Heart Failure Hospitalization in Patients With Advanced
           Heart Failure and Reduced Ejection Fraction
    • Authors: Laura Houard Mihaela S. Amzulescu Geoffrey Colin Helene Langet Sebastian Militaru Michel F. Rousseau Sylvie A. Ahn Jean-Louis J. Vanoverschelde Anne-Catherine Pouleur Bernhard L. Gerber Division of Cardiology, Department of Cardiovascular Diseases, Cliniques Universitaires St. Luc (L.H; M.S.A, G.C, S.M, M.F.R, S.A.A, J.-L.J.V, A.-C.P, B.L.G.). Pôle de Recherche Cardiovasculaire (CARD), Institut de Recherche Expérimentale et Clinique (IREC), Université Catholique de Louvain, Brussels, Belgium (L.H, M.S.A, S.M, M.F.R, S.A.A, J.-L.J.V, A.-C.P, B.L.G.). Philips Clinical Research Board, Suresnes, France (H.L.).
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.
      BackgroundPulmonary transit time (PTT) from first-pass perfusion imaging is a novel parameter to evaluate hemodynamic congestion by cardiac magnetic resonance (cMR). We sought to evaluate the additional prognostic value of PTT in heart failure with reduced ejection fraction over other well-validated predictors of risk including the Meta-Analysis Global Group in Chronic Heart Failure risk score and ischemic cause.MethodsWe prospectively followed 410 patients with chronic heart failure with reduced ejection fraction (61±13 years, left ventricular (LV) ejection fraction 24±7%) who underwent a clinical cMR to assess the prognostic value of PTT for a primary endpoint of overall mortality and secondary composite endpoint of cardiovascular death and heart failure hospitalization. Normal reference values of PTT were evaluated in a population of 40 asymptomatic volunteers free of cardiovascular disease.ResultsPTT was significantly increased in patients with heart failure with reduced ejection fraction as compared to controls (9±6 beats and 7±2 beats, respectively,P<0.001), and correlated not only with New York Heart Association class, cMR–LV and cMR–right ventricular (RV) volumes, cMR-RV and cMR-LV ejection fraction, and feature tracking global longitudinal strain, but also with cardiac output. Over 6-year median follow-up, 182 patients died and 200 reached the secondary endpoint. By multivariate Cox analysis, PTT was an independent and significant predictor of both endpoints after adjustment for Meta-Analysis Global Group in Chronic Heart Failure risk score and ischemic cause. Importantly in multivariable analysis, PTT in beats had significantly higher additional prognostic value to predict not only overall mortality (χ2to improve, 12.3; hazard ratio, 1.35 [95% CI, 1.16–1.58];P<0.001) but also the secondary composite endpoints (χ2to improve=20.1; hazard ratio, 1.23 [95% CI, 1.21–1.60];P<0.001) than cMR-LV ejection fraction, cMR-RV ejection fraction, LV–feature tracking global longitudinal strain, or RV–feature tracking global longitudinal strain. Importantly, PTT was independent and complementary to both pulmonary artery pressure and reduced RV ejection fraction<42% to predict overall mortality and secondary combined endpoints.ConclusionsDespite limitations in temporal resolution, PTT derived from first-pass perfusion imaging provides higher and independent prognostic information in heart failure with reduced ejection fraction than clinical and other cMR parameters, including LV and RV ejection fraction or feature tracking global longitudinal strain.REGISTRATIONURL:https://www.clinicaltrials.gov; Unique identifier: NCT03969394.
      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-13T10:00:05Z
      DOI: 10.1161/CIRCIMAGING.120.011680
       
  • In This Issue of the Journal
    • Authors: Robert J. Gropler Editor in Chief; Circulation: Cardiovascular Imaging
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-13T10:00:02Z
      DOI: 10.1161/CIRCIMAGING.120.012351
       
  • Multimodality Imaging in Endomyocardial Fibrosis: Diagnosis and Assessment
           of the Extent of the Disease
    • Authors: Daniela do Carmo Rassi Paula Chiavenato Marçal Cecília Beatriz Bittencourt Viana Cruz João Batista Masson Silva Viviane Tiemi Hotta São Francisco de Assis Hospital; Goiânia, Brazil Heart Institute of the University of São Paulo (INCOR/FMUSP), São Paulo, Brazil Federal University of Goiás Clinical Hospital Medical School, Goiânia, Brazil
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-07T10:00:02Z
      DOI: 10.1161/CIRCIMAGING.120.012093
       
  • Computed Tomography-Derived Transesophageal Echocardiographic Views
    • Authors: Federico Fortuni Kensuke Hirasawa Ana I. Marques Stephan M. Pio Surenjav Chimed Rodolfo Lustosa Catherina Tjahjadi Xu Wang Jeroen J. Bax Nina Ajmone Marsan Victoria Delgado Department of Cardiology, Leiden University Medical Center, The Netherlands (F.F; K.H, S.M.P, S.C, R.L, C.T, X.W, J.J.B, N.A.M, V.D.). Department of Molecular Medicine, Unit of Cardiology, University of Pavia, Italy (F.F.). Department of Cardiology, Hospital Garcia de Orta, Almada, Portugal (A.I.M.).
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2021-01-06T07:00:01Z
      DOI: 10.1161/CIRCIMAGING.120.011107
       
  • Misleading Echocardiographic Diagnosis of an Infant With Dilated
           Cardiomyopathy
    • Authors: Yu-Hsuan Liu Shu-Chien Huang Jou-Kou Wang Chun-An Chen Department of Pediatrics; Hualien Tzu Chi Hospital, Hualien, Taiwan (Y.-H.L.). Department of Cardiology, National Taiwan University Children’s Hospital, Taipei (Y.-H.L., J.-K.W., C.-A.C.). Division of Cardiovascular Surgery, Department of Surgery, National Taiwan University Hospital National Taiwan University College of Medicine, Taipei, Taiwan (S.-C.H.). Department of Pediatrics, Medical College, National Taiwan University, Taipei (J.-K.W., C.-A.C.).
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2020-12-24T03:19:16Z
      DOI: 10.1161/CIRCIMAGING.120.011075
       
  • Unexpected Aortitis Mimicking an Ascending Aorta Intramural Hematoma in
           Ankylosing Spondylitis
    • Authors: Igor Vendramin Monica De Gaspari Andrea Lechiancole Uberto Bortolotti Ugolino Livi Cardiothoracic Department, University Hospital of Udine, Italy. (I.V; A.L, U.B, U.L.) Department of Pathology, University Hospital of Udine, Italy. (M.D.G.)
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2020-12-24T03:18:28Z
      DOI: 10.1161/CIRCIMAGING.120.011014
       
  • Primary Aortic Angiosarcoma Presenting as Progressive Thrombosis of the
           Thoracic Aorta
    • Authors: Francesco Squizzato Franco Grego Division of Vascular; Public Health, University of Padua, Italy.
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2020-12-24T03:17:17Z
      DOI: 10.1161/CIRCIMAGING.120.010854
       
  • Recurrent Tachyarrhythmia due to Giant Hiatal Hernia
    • Authors: Luca Botta Gianluca Folesani Davide Pacini Cardiac Surgery Unit; Cardio-Thoraco-Vascular Department, S. Orsola Hospital, University of Bologna, Italy.
      Abstract: Circulation: Cardiovascular Imaging, Ahead of Print.

      Citation: Circulation: Cardiovascular Imaging
      PubDate: 2020-12-24T03:13:28Z
      DOI: 10.1161/CIRCIMAGING.120.010809
       
 
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