Subjects -> MEDICAL SCIENCES (Total: 8665 journals)
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CARDIOVASCULAR DISEASES (338 journals)                  1 2 | Last

Showing 1 - 200 of 338 Journals sorted alphabetically
Acta Angiologica     Open Access   (Followers: 5)
Acta Cardiologica     Hybrid Journal   (Followers: 2)
Acute Cardiac Care     Hybrid Journal   (Followers: 8)
Adipositas - Ursachen, Folgeerkrankungen, Therapie     Hybrid Journal  
AJP Heart and Circulatory Physiology     Hybrid Journal   (Followers: 12)
Aktuelle Kardiologie     Hybrid Journal   (Followers: 1)
American Heart Journal     Hybrid Journal   (Followers: 59)
American Journal of Cardiology     Hybrid Journal   (Followers: 67)
American Journal of Cardiovascular Drugs     Hybrid Journal   (Followers: 17)
American Journal of Hypertension     Hybrid Journal   (Followers: 28)
Anales de Cirugia Vascular     Full-text available via subscription   (Followers: 1)
Anatolian Journal of Cardiology     Open Access   (Followers: 6)
Angiología     Full-text available via subscription  
Angiologia e Cirurgia Vascular     Open Access   (Followers: 1)
Angiology     Hybrid Journal   (Followers: 3)
Annales de Cardiologie et d'Angéiologie     Full-text available via subscription   (Followers: 1)
Annals of Circulation     Open Access   (Followers: 2)
Annals of Noninvasive Electrocardiology     Hybrid Journal   (Followers: 1)
Annals of Pediatric Cardiology     Open Access   (Followers: 12)
AORTA     Open Access  
Archives of Cardiovascular Diseases     Full-text available via subscription   (Followers: 5)
Archives of Cardiovascular Diseases Supplements     Full-text available via subscription   (Followers: 3)
Archives of Cardiovascular Imaging     Open Access   (Followers: 2)
Archivos de cardiología de México     Open Access   (Followers: 1)
Argentine Journal of Cardiology (English edition)     Open Access   (Followers: 2)
Arquivos Brasileiros de Cardiologia     Open Access   (Followers: 2)
Arrhythmia & Electrophysiology Review     Open Access   (Followers: 1)
Arteriosclerosis, Thrombosis and Vascular Biology     Full-text available via subscription   (Followers: 33)
Artery Research     Hybrid Journal   (Followers: 4)
ARYA Atherosclerosis     Open Access  
ASAIO Journal     Hybrid Journal   (Followers: 4)
ASEAN Heart Journal     Open Access   (Followers: 2)
Asian Cardiovascular and Thoracic Annals     Hybrid Journal   (Followers: 2)
Aswan Heart Centre Science & Practice Services     Open Access   (Followers: 1)
Atherosclerosis : X     Open Access  
Bangladesh Heart Journal     Open Access   (Followers: 3)
Basic Research in Cardiology     Hybrid Journal   (Followers: 9)
BMC Cardiovascular Disorders     Open Access   (Followers: 22)
Brain Circulation     Open Access   (Followers: 1)
British Journal of Cardiology     Full-text available via subscription   (Followers: 17)
Canadian Journal of Cardiology     Hybrid Journal   (Followers: 17)
Cardiac Cath Lab Director     Full-text available via subscription  
Cardiac Electrophysiology Review     Hybrid Journal   (Followers: 2)
Cardiac Failure Review     Open Access   (Followers: 1)
Cardiocore     Full-text available via subscription   (Followers: 1)
Cardiogenetics     Open Access   (Followers: 3)
Cardiology     Full-text available via subscription   (Followers: 19)
Cardiology and Angiology: An International Journal     Open Access   (Followers: 1)
Cardiology and Therapy     Open Access   (Followers: 11)
Cardiology Clinics     Full-text available via subscription   (Followers: 13)
Cardiology in Review     Hybrid Journal   (Followers: 8)
Cardiology in the Young     Hybrid Journal   (Followers: 34)
Cardiology Journal     Open Access   (Followers: 5)
Cardiology Plus     Open Access   (Followers: 1)
Cardiology Research     Open Access   (Followers: 14)
Cardiology Research and Practice     Open Access   (Followers: 10)
Cardiopulmonary Physical Therapy Journal     Hybrid Journal   (Followers: 9)
Cardiorenal Medicine     Full-text available via subscription   (Followers: 1)
Cardiothoracic Surgeon     Open Access   (Followers: 1)
CardioVasc     Full-text available via subscription   (Followers: 1)
Cardiovascular & Haematological Disorders - Drug Targets     Hybrid Journal   (Followers: 1)
Cardiovascular & Hematological Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 2)
CardioVascular and Interventional Radiology     Hybrid Journal   (Followers: 15)
Cardiovascular and Thoracic Open     Open Access  
Cardiovascular Diabetology     Open Access   (Followers: 10)
Cardiovascular Drugs and Therapy     Hybrid Journal   (Followers: 14)
Cardiovascular Endocrinology & Metabolism     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering     Hybrid Journal   (Followers: 1)
Cardiovascular Engineering and Technology     Hybrid Journal   (Followers: 1)
Cardiovascular Intervention and Therapeutics     Hybrid Journal   (Followers: 5)
Cardiovascular Journal     Open Access   (Followers: 6)
Cardiovascular Journal of Africa     Full-text available via subscription   (Followers: 5)
Cardiovascular Journal of South Africa     Full-text available via subscription   (Followers: 1)
Cardiovascular Medicine in General Practice     Full-text available via subscription   (Followers: 7)
Cardiovascular Pathology     Hybrid Journal   (Followers: 4)
Cardiovascular Regenerative Medicine     Open Access  
Cardiovascular Research     Hybrid Journal   (Followers: 15)
Cardiovascular Revascularization Medicine     Hybrid Journal   (Followers: 1)
Cardiovascular System     Open Access  
Cardiovascular Therapeutics     Open Access   (Followers: 1)
Cardiovascular Toxicology     Hybrid Journal   (Followers: 6)
Cardiovascular Ultrasound     Open Access   (Followers: 5)
Case Reports in Cardiology     Open Access   (Followers: 7)
Catheterization and Cardiovascular Interventions     Hybrid Journal   (Followers: 3)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Chest     Full-text available via subscription   (Followers: 103)
Choroby Serca i Naczyń     Open Access   (Followers: 1)
Circulation     Hybrid Journal   (Followers: 265)
Circulation : Cardiovascular Imaging     Hybrid Journal   (Followers: 15)
Circulation : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
Circulation : Cardiovascular Quality and Outcomes     Hybrid Journal   (Followers: 11)
Circulation : Genomic and Precision Medicine     Hybrid Journal   (Followers: 16)
Circulation : Heart Failure     Hybrid Journal   (Followers: 26)
Circulation Research     Hybrid Journal   (Followers: 35)
Cirugía Cardiovascular     Open Access  
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clínica e Investigación en arteriosclerosis (English Edition)     Hybrid Journal  
Clinical and Experimental Hypertension     Hybrid Journal   (Followers: 3)
Clinical Cardiology     Hybrid Journal   (Followers: 10)
Clinical Hypertension     Open Access   (Followers: 5)
Clinical Medicine Insights : Cardiology     Open Access   (Followers: 6)
Clinical Research in Cardiology     Hybrid Journal   (Followers: 5)
Clinical Research in Cardiology Supplements     Hybrid Journal  
Clinical Trials and Regulatory Science in Cardiology     Open Access   (Followers: 4)
Congenital Heart Disease     Hybrid Journal   (Followers: 6)
Congestive Heart Failure     Hybrid Journal   (Followers: 4)
Cor et Vasa     Full-text available via subscription   (Followers: 1)
Coronary Artery Disease     Hybrid Journal   (Followers: 3)
CorSalud     Open Access  
Critical Pathways in Cardiology     Hybrid Journal   (Followers: 5)
Current Cardiology Reports     Hybrid Journal   (Followers: 6)
Current Cardiology Reviews     Hybrid Journal   (Followers: 3)
Current Cardiovascular Imaging Reports     Hybrid Journal   (Followers: 1)
Current Cardiovascular Risk Reports     Hybrid Journal  
Current Heart Failure Reports     Hybrid Journal   (Followers: 5)
Current Hypertension Reports     Hybrid Journal   (Followers: 6)
Current Hypertension Reviews     Hybrid Journal   (Followers: 6)
Current Opinion in Cardiology     Hybrid Journal   (Followers: 13)
Current Problems in Cardiology     Hybrid Journal   (Followers: 3)
Current Research : Cardiology     Full-text available via subscription   (Followers: 1)
Current Treatment Options in Cardiovascular Medicine     Hybrid Journal   (Followers: 1)
Current Vascular Pharmacology     Hybrid Journal   (Followers: 5)
CVIR Endovascular     Open Access   (Followers: 1)
Der Kardiologe     Hybrid Journal   (Followers: 1)
Echo Research and Practice     Open Access   (Followers: 2)
Echocardiography     Hybrid Journal   (Followers: 4)
Egyptian Heart Journal     Open Access   (Followers: 2)
Egyptian Journal of Cardiothoracic Anesthesia     Open Access  
ESC Heart Failure     Open Access   (Followers: 4)
European Cardiology Review     Open Access   (Followers: 1)
European Heart Journal     Hybrid Journal   (Followers: 67)
European Heart Journal - Cardiovascular Imaging     Hybrid Journal   (Followers: 10)
European Heart Journal - Cardiovascular Pharmacotherapy     Full-text available via subscription   (Followers: 2)
European Heart Journal - Quality of Care and Clinical Outcomes     Hybrid Journal  
European Heart Journal : Acute Cardiovascular Care     Hybrid Journal   (Followers: 1)
European Heart Journal : Case Reports     Open Access   (Followers: 1)
European Heart Journal Supplements     Hybrid Journal   (Followers: 7)
European Journal of Cardio-Thoracic Surgery     Hybrid Journal   (Followers: 9)
European Journal of Cardio-Thoracic Surgery Supplements     Full-text available via subscription   (Followers: 2)
European Journal of Cardiovascular Nursing     Hybrid Journal   (Followers: 5)
European Journal of Heart Failure     Hybrid Journal   (Followers: 13)
European Journal of Preventive Cardiology.     Hybrid Journal   (Followers: 6)
European Stroke Organisation     Hybrid Journal   (Followers: 3)
Experimental & Translational Stroke Medicine     Open Access   (Followers: 9)
Expert Review of Cardiovascular Therapy     Full-text available via subscription   (Followers: 3)
Folia Cardiologica     Open Access  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontiers in Cardiovascular Medicine     Open Access   (Followers: 1)
Future Cardiology     Hybrid Journal   (Followers: 5)
General Thoracic and Cardiovascular Surgery     Hybrid Journal   (Followers: 3)
Global Cardiology Science and Practice     Open Access   (Followers: 5)
Global Heart     Hybrid Journal   (Followers: 3)
Heart     Hybrid Journal   (Followers: 48)
Heart and Mind     Open Access  
Heart and Vessels     Hybrid Journal  
Heart Failure Clinics     Full-text available via subscription   (Followers: 2)
Heart Failure Reviews     Hybrid Journal   (Followers: 3)
Heart India     Open Access   (Followers: 2)
Heart International     Full-text available via subscription  
Heart Rhythm     Hybrid Journal   (Followers: 11)
Heart Views     Open Access   (Followers: 2)
HeartRhythm Case Reports     Open Access  
Hellenic Journal of Cardiology     Open Access   (Followers: 1)
Herz     Hybrid Journal   (Followers: 2)
High Blood Pressure & Cardiovascular Prevention     Full-text available via subscription   (Followers: 2)
Hypertension     Full-text available via subscription   (Followers: 23)
Hypertension     Open Access   (Followers: 2)
Hypertension in Pregnancy     Hybrid Journal   (Followers: 9)
Hypertension Research     Hybrid Journal   (Followers: 4)
Ibrahim Cardiac Medical Journal     Open Access  
IJC Heart & Vessels     Open Access   (Followers: 1)
IJC Heart & Vasculature     Open Access   (Followers: 1)
IJC Metabolic & Endocrine     Open Access   (Followers: 1)
Indian Heart Journal     Open Access   (Followers: 5)
Indian Journal of Cardiovascular Disease in Women WINCARS     Open Access  
Indian Journal of Thoracic and Cardiovascular Surgery     Hybrid Journal  
Indian Pacing and Electrophysiology Journal     Open Access   (Followers: 1)
Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery     Hybrid Journal   (Followers: 1)
Insuficiencia Cardíaca     Open Access  
Interactive CardioVascular and Thoracic Surgery     Hybrid Journal   (Followers: 7)
International Cardiovascular Forum Journal     Open Access  
International Journal of Angiology     Hybrid Journal   (Followers: 2)
International Journal of Cardiology     Hybrid Journal   (Followers: 17)
International Journal of Cardiology Hypertension     Open Access   (Followers: 1)
International Journal of Cardiovascular and Cerebrovascular Disease     Open Access   (Followers: 3)
International Journal of Cardiovascular Imaging     Hybrid Journal   (Followers: 2)
International Journal of Cardiovascular Research     Hybrid Journal   (Followers: 6)
International Journal of Heart Rhythm     Open Access  
International Journal of Hypertension     Open Access   (Followers: 8)
International Journal of Hyperthermia     Open Access  
International Journal of Stroke     Hybrid Journal   (Followers: 32)
International Journal of the Cardiovascular Academy     Open Access  
Interventional Cardiology Clinics     Full-text available via subscription   (Followers: 2)
Interventional Cardiology Review     Open Access  
JACC : Basic to Translational Science     Open Access   (Followers: 5)
JACC : Cardiovascular Imaging     Hybrid Journal   (Followers: 18)
JACC : Cardiovascular Interventions     Hybrid Journal   (Followers: 19)
JACC : Heart Failure     Full-text available via subscription   (Followers: 14)
JAMA Cardiology     Hybrid Journal   (Followers: 30)

        1 2 | Last

Similar Journals
Journal Cover
Acta Cardiologica
Journal Prestige (SJR): 0.404
Citation Impact (citeScore): 1
Number of Followers: 2  
 
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 0001-5385 - ISSN (Online) 0373-7934
Published by Peeters Publishers Homepage  [62 journals]
  • Modulating effect of cardiac rehabilitation on autonomic nervous system
           function in patients with coronary artery disease
    • Authors: poj@peeters-leuven.be
      Abstract: Introduction: Autonomic nervous system (ANS) dysfunction is associated with prognosis in coronary artery disease (CAD). We aimed to study the cardiac rehabilitation (CR) modulating effect on autonomic function, through heart rate variability (HRV) and heart rate recovery (HRR) after exercise, in CAD patients and the associated factors.Methods: This study is a retrospective analysis of CAD patients in sinus rhythm who complete a single-centre CR programme and complementary evaluation including HRV study, cardiopulmonary exercise testing, echocardiogram.Results: Our sample included 142 CAD patients (85.9% male, 57.8 ± 10.2 years, 85% post-acute coronary syndrome, 15% stable CAD). There was a significant improvement in SDNN (120.7 ± 40.7 ms vs 127.6 ± 41.5 ms; P = 0.019), resting HR (71.3 ± 10.7 min¯?1 vs 69.0 ± 10.9 min¯?1; P = 0.015) and HRR (23.8 ± 12.3 min¯?1 vs 27.1 ± 12.5 min¯?1; P = 0.017) following CR. Lower erythrocyte sedimentation rate (OR 0.911; 95% confidence interval (CI) 0.838-0.989, P = 0.027), normal left ventricular (LV) function/mild LV systolic dysfunction (OR 7.879; 95% CI 2.753-17.351, P = 0.009) and SDNN lower than 100 ms (OR 9.325; 95% CI 1.775-48.978, P = 0.008) were independently associated with SDNN improvement; quit smoking (OR 4.323; 95% CI 1.136-16.454, P = 0.014) and abnormal HRR (OR 8.023; 95% CI 1.049-64.811, P = 0.035) were independently associated with HRR improvement.Conclusion: The cardiac rehabilitation programme induced a positive modulation of the autonomic function in CAD patients, as reflected by SDNN and HRR improvement. This benefit was associated with ANS baseline dysfunction, lower systemic inflammation, quit smoking and normal LV function to mild left ventricular systolic dysfunction.
      PubDate: Mon, 05 Dec 2016 11:12:26 GMT
       
  • Belgian Society of Cardiology Belgian Heart Rhythm Association (BeHRA)
    • Authors: poj@peeters-leuven.be
      Abstract: Abstracts
      PubDate: Mon, 05 Dec 2016 11:07:20 GMT
       
  • Pedunculated left atrial mass
    • Authors: poj@peeters-leuven.be
      Abstract: not available
      PubDate: Mon, 05 Dec 2016 11:07:03 GMT
       
  • Giant left atrium: back to basic chest X-ray interpretation
    • Authors: poj@peeters-leuven.be
      Abstract: not available
      PubDate: Mon, 05 Dec 2016 11:05:48 GMT
       
  • Pacing lead is more easily located at RVOT septum in patients with severe
           tricuspid regurgitation
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: The optimal right ventricular (RV) pacing site in patients referred for permanent cardiac pacing remains controversial. The present study aims to evaluate at which pacing site the electrode is more easily and steadily located in patients with severe tricuspid regurgitation (TR).Methods and results: We prospectively enrolled 50 patients with severe TR for permanent pacemaker implantation and randomly divided them into two groups to receive either RV apex (group A) or RV outflow tract (RVOT) pacing (group B). Time of X-ray exposure for ventricular lead deployment, incidence of intra-procedural dislodgement and post-procedural cTnT level were compared between the two groups. Lead performance and echocardiographic parameters were evaluated during follow-up. Fractional shortening (FS) of both RV body and RVOT were assessed so as to analyse the wall motion of the two RV components. As a result, RV body demonstrated a significantly higher FS than RVOT (36.7 ± 5.0% vs 30.0 ± 4.6%, P < 0.01) among all TR cases. Compared with group A, less X-ray time was needed for ventricular lead implantation in group B (114.2 ± 28.9 s vs 147.2 ± 55.6 s, P = 0.011) with a lower incidence of intra-procedural dislodgement (4% vs 24%, P = 0.042). RVOT pacing was also associated with a lower cTnT level 6 and 24 hours after procedure (P < 0.01). Lead performance and echocardiographic parameters during follow-up revealed no difference between RV apex and RVOT pacing.Conclusion: In patients with severe TR, the ventricular lead is more easily and steadily located at RVOT septum than at the RV apex with shorter fluoroscopy time, lower incidence of intra-procedural dislodgement and less myocardial injury.
      PubDate: Mon, 05 Dec 2016 11:05:24 GMT
       
  • Long-term safety and efficacy of supraventricular tachycardia ablation
           with a simplified approach
    • Authors: poj@peeters-leuven.be
      Abstract: Introduction: Catheter-ablation (CA) is routinely used for the treatment of atrio-ventricular nodal re-entrant tachycardia (AVNRT) and accessory AV-pathways and is usually performed with 4 or 5 catheters. This study reports the short- and long-term results of an alternative simplified approach with a 2-catheter configuration for both electrophysiological study (EPS) and CA in patients with re-entrant supraventricular tachycardias.Methods: In total, 274 consecutive patients who underwent EPS with a view to curative CA for AVNRT or AVRT were enrolled. A 2-catheter configuration was routinely used. Ablation success, acute in-hospital complications, symptoms recurrence, arrhythmia recurrence were recorded.Results: 195 patients underwent ablation of AVNRT and 79 of a single AP. Immediate success after CA ablation was achieved in 99.6% of patients. Major complications occurred in 2 patients (0.73%, 2 cases of complete AV block, one of which requiring pacemaker implantation after 1 year, one during typical AVNRT ablation and one during epicardial AP-ablation). Vascular complications occurred in 4 patients (1.4%, 3 partial femoral vein thrombosis without embolic events, one femoral arteriovenous fistula). Minimal pericardial effusion occurred in 6 patients (2.2%). All vascular complications were medically successfully treated not requiring surgery. The mean follow-up was 86 months. Arrhythmia recurrence was observed in 5.6% of patients (2.6% with AP, 2.9% with AVNRT); a second successful catheter ablation was performed in 2.9%.Conclusions: CA with simplified approach is effective in the treatment of supraventricular tachycardia due to APs and AVNRT and is associated with a low incidence of major and minor complications and late recurrence of arrhythmias.
      PubDate: Mon, 05 Dec 2016 11:02:09 GMT
       
  • The effects of dialysis-type on left ventricular function in non-diabetic
           end-stage renal disease patients
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: In this study we aimed to investigate a possible difference in left ventricular function in patients undergoing peritoneal dialysis (PD) and haemodialysis (HD) using 2D echocardiography.Methods: A total of 84 patients were recruited in the study. Both PD and HD groups consisted of 42 end-stage renal disease patients. Patients with left ventricular ejection fraction (EF) < 50%, diabetes mellitus and coronary artery disease were excluded. Baseline characteristics and conventional tissue Doppler echocardiography parameters were recorded. Left ventricular longitudinal (Ls), circumferential (Cs) and radial strain (R) along with strain rate were also recorded in the speckle-tracking echocardiography. These values were compared between the two groups.Results: No significant difference was observed between PD and HD patients, in terms of mean time from diagnosis of chronic kidney disease to initiation of the study, mean time from first dialysis to initiation of the study, left ventricular EF, age, sex and heart rate. Left ventricular hypertrophy was also more frequent in HD group and the patients had a higher left ventricular mass index. Left ventricular global Ls, LSRs, LSRe, LSRa and global Rs, RSRs, RSRe, RSRa were detected to be lower in HD patients.Conclusions: Longitudinal and radial left ventricular mechanics were found to be better preserved in patients undergoing peritoneal dialysis when compared to haemodialysis patients. Consequently, it can be concluded that peritoneal dialysis provides better protection on left ventricular systolic function compared to haemodialysis.
      PubDate: Mon, 05 Dec 2016 10:54:34 GMT
       
  • Assessing extensive cardiac echography examination for detecting foetal
           congenital heart defects during early and late gestation: a systematic
           review and meta-analysis
    • Authors: poj@peeters-leuven.be
      Abstract: Background: Extensive cardiac echography examination (ECEE) can identify cardiac heart defects (CHDs) in utero. However, there is not yet a clear appraisal of ECEE¯?s performance in detecting foetal CHDs as a function of gestational time. In this study, we assessed the diagnostic efficacy of ECEE in detecting CHDs during early gestation (< 18 weeks) and late gestation (≥ 18 weeks).Methods: MEDLINE, EMBASE, and Cochrane CENTRAL databases were searched for ECEE studies that had a prenatal diagnosis later validated by echocardiography, catheterization, surgery, or autopsy and allowed construction of 2 í? 2 tables. Pooled sensitivity, specificity, and diagnostic odds ratio of ECEE during early and late gestation were calculated. Summary receiver operating characteristic curves were plotted to obtain area under the curve (AUC) values.Results: ECEE in late gestation had a slightly superior sensitivity relative to that in early gestation (0.90 vs 0.86, respectively), while ECEE during both early and late gestation displayed near-perfect specificity (1.00 vs 1.00, respectively). ECEE in late gestation displayed a superior diagnostic odds ratio relative to that in late gestation (3,502.81 vs 1,076.79, respectively). ECEE during both early and late gestation displayed similar overall diagnostic accuracy in terms of AUC (0.9861 vs 0.9783, respectively).Conclusions: ECEE performed before the 18-week gestational time point provides nearly equivalent diagnostic accuracy to ECEE performed on or after the 18-week gestational time point. However, ECEE conducted prior to week 11 may not be advisable due to the immature development of foetal heart structures.
      PubDate: Mon, 05 Dec 2016 10:52:03 GMT
       
  • Assessment of cardiovascular risk factors in patients with subclinical
           hypothyroidism
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: Overt hypothyroidism is associated with accelerated arteriosclerosis and cardiovascular disease (CVD). Whether subclinical hypothyroidism (SCH) is also associated with increased cardiovascular risk remains controversial. The present study aimed to evaluate risk factors for CVD in SCH patients in comparison to healthy controls.Methods: We assessed common lipid variables, fasting glucose, insulin, malondialdehyde (MDA), total bilirubin (TB) and homeostasis model assessment (HOMA) index in 34 patients with SCH and 34 healthy controls.Results: In SCH there was an elevated total cholesterol (TC) (P < 0.01), low-density lipoprotein cholesterol (LDL-C) (P < 0.01) and fasting glucose (P < 0.001) concentration, a diminished TB value (P < 0.001) and borderline elevated triglycerides (TG) (not reaching the limit of significance, P = 0.063). LDL-C to HDL-C ratio was also elevated (P < 0.05). MDA and HOMA index were higher in the SCH subjects but this difference was not statistically significant. Insulin, high-density lipoprotein cholesterol (HDL-C) remained unaltered. TSH was positively correlated with TC, LDL-C, fasting glucose (P < 0.01) and MDA (P < 0.001) and inversely correlated with TB (P < 0.01). HOMA index was positively correlated with TG (P < 0.001) and negatively correlated with HDL-C (P < 0.01). In the SCH group, MDA was positively correlated with TC, LDL-C and TG (P < 0.05). TB was negatively correlated with TG (P < 0.05).Conclusion: Our findings suggest that cardiovascular risk might be increased in patients with subclinical hypothyroidism which provides a possible explanation for the early detection and treatment of such individuals.
      PubDate: Mon, 05 Dec 2016 10:49:04 GMT
       
  • Total serum bilirubin is an independent risk factor for coronary artery
           disease in men compared to women
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: An elevated total serum bilirubin level has been demonstrated to be protective against cardiovascular disease with the majority of evidence limited to males. We assessed the hypothesis that total bilirubin is an independent risk factor for the presence of coronary artery disease (CAD) in men compared to women in high-risk patients.Methods and results: Analysis was performed on 563 men and 249 women presenting for coronary angiography at our institution between October 2009 and March 2014. CAD was defined by 50% stenosis or more in the left anterior descending artery, left circumflex artery or right coronary artery. CAD was present in 78% of men and 55% of women. In males, patients with CAD had lower median total serum bilirubin levels compared to patients without CAD (12 vs 13 μmol/L, P = 0.002). There was no difference seen in the female population (10 vs 10 μmol/L, P = 0.344). On multivariate logistic regression, total serum bilirubin was an independent risk factor of CAD in the males (OR 0.96; 95% CI 0.93-0.99; P = 0.018) but not in females (OR 1.00; 95% CI 0.93-1.08; P = 0.908).Conclusion: Total serum bilirubin is an independent risk factor for angiographically defined CAD in men and not in women. Serum bilirubin is readily available and inexpensive and may be a biomarker in addition to recognised cardiovascular risk factors.
      PubDate: Mon, 05 Dec 2016 10:44:33 GMT
       
  • Glutathione S-transferase M1 and T1 (rs4025935 and rs71748309) null
           genotypes are associated with increased susceptibility to coronary artery
           disease in Indian populations
    • Authors: poj@peeters-leuven.be
      Abstract: Background: Various other biochemical and genetic factors apart from conventional risk factors are known to play an important role in the pathogenesis of coronary artery disease. Polymorphism in the glutathione S-transferases gene leads to alteration in glutathione S-transferase levels which play an important role in detoxification of free radicals particularly those present in cigarette smoke.Methods: One hundred angiographically diagnosed subjects and 100 normal controls were recruited. Detailed history and clinical examination of blood samples were collected and assessed for various biochemical parameters. GSTM1 and GSTT1 genotyping for GST gene was done by using multiplex polymerase chain reaction (PCR).Results: The frequency of the GSTM1null genotype was found to be significantly higher in cases in the total population (P < 0.0003), in smokers (P = 0.018) and in subjects with hypertension (P = 0.04). Though distribution of the GSTT1null genotype was not found to be significantly different in cases and controls, its concomitant presence with the GSTM1null genotype was found to increase the risk of CAD in all subjects (OR = 2.28) and in smokers (P = 0.03), and to pose an additional risk in hypertensive (P = 0.01) and diabetic (P < 0.001) subjects. The most likely explanation for these findings may be that polymorphisms in the GST gene lead possibly to alteration in GST levels or activity which may further lead to variable detoxification of various toxins, mostly epoxides, including those present in cigarette smoke.Conclusion: We conclude that GSTM1null genotype increases the risk of CAD in all subjects including smokers. Concomitant presence of GSTT1null and GSTM1null genotype was found to further increase the risk in all subjects: smokers, diabetic and hypertensive patients.
      PubDate: Mon, 05 Dec 2016 10:40:53 GMT
       
  • Fragmented QRS complex on ECG is associated with ventricular arrhythmias
           in patients with a prior myocardial infarction
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: The aim of this study was to investigate the relations between fragmented QRS complex (fQRS) on ECG and the incidence of ventricular arrhythmias in patients with a prior myocardial infarction (MI).Methods: A total of 321 patients with MI were divided into the fQRS (n = 167) and non-fQRS group (n = 154). Standard 12-lead ECG and 24-h Holter monitoring were performed in all patients.Results: The incidence of frequent (28.7% vs 17.5%, P < 0.05) or high-risk ventricular premature contractions (34.1% vs 23.4%, P < 0.05) in the fQRS group was higher than in the non-fQRS group. The incidence of non-sustained ventricular tachycardia in the fQRS group was also higher than in the non-fQRS group (12.0% vs 4.5%, P < 0.05). Patients with a fQRS duration of > 0.12 s had a higher incidence of ventricular arrhythmias (70.6%) than patients with fQRS duration between 0.101 and 0.119 s (42.6%, P < 0.05), or those with fQRS duration of 0.10 s or less (22.9%, P < 0.05). Logistic regression analysis showed that fQRS was an independent predictor for high-risk ventricular premature contractions (OR, 1.482, 95% CI, 1.19-3.22, P = 0.02), or non-sustained ventricular tachycardia (OR, 1.982, 95% CI, 1.30-3.76, P = 0.01).Conclusion: fQRS was associated with an increased incidence of high-risk ventricular premature contractions and non-sustained ventricular tachycardia. fQRS may be used to predict future risk of ventricular arrhythmias in patients with a prior myocardial infarction.
      PubDate: Mon, 05 Dec 2016 10:35:05 GMT
       
  • Prognostic value of CHA2DS2-VASc score in patients with ST-segment
           elevation myocardial infarction who underwent primary percutaneous
           coronary intervention
    • Authors: poj@peeters-leuven.be
      Abstract: Objectives: The aim of the study was to investigate the relationship between CHA2DS2-VASc score and in-hospital and long-term all-cause and cardiovascular mortality in patients with STEMI who underwent primary PCI.Methods: In this retrospective study, 604 patients, admitted to the emergency department with a diagnosis of STEMI, were included. The study patients were divided into three risk groups according to CHA2DS2-VASc score: low-risk group (1 point), moderate-risk group (2 points), and high-risk group (3 points and higher), respectively.Results: The mean follow-up time was 680 ± 286 days. In the high-risk group, the rates of in-hospital and long-term all-cause and cardiovascular mortality were higher than in the other groups. The Kaplan-Meier curves for the group with CHA2DS2-VASc scores > 2 indicated a significantly shorter long-term survival (P < 0.001). In the receiver operating characteristic curve analysis, CHA2DS2-VASc scores > 2 were identified as an effective predictive cut-off point for all-cause mortality in STEMI (area under curve = 0.850, 95% confidence interval: 0.819-0.878, P < 0.001). CHA2DS2-VASc score > 2 yielded a sensitivity of 70.18% and a specificity of 83%.Conclusion: The CHA2DS2-VASc is a simple and easily calculated score that provides an additional level of risk stratification beyond that provided by conventional risk scores in predicting in-hospital and long-term all-cause and cardiovascular mortality in STEMI.
      PubDate: Mon, 05 Dec 2016 10:30:47 GMT
       
  • Five-year outcome of consecutive unprotected left main percutaneous
           coronary interventions
    • Authors: poj@peeters-leuven.be
      Abstract: Objectives: We aimed to describe the procedural characteristics and 5-year outcome of consecutive patients undergoing unprotected left main coronary artery (ULMCA) percutaneous coronary intervention (PCI) at our tertiary care centre between 1 January 2007 and 31 December 2008.Methods and results: 76 patients underwent ULMCA PCI during the study period. Drug-eluting stents were used in 61. The mean EuroSCORE II, additive and logistic EuroSCOREs and SYNTAX score were 14.81, 10.2, 25.25 and 27.3, respectively. 30-day and 5-year mortality were 14.5% and 50%, respectively, with early mortality related exclusively to circulatory causes and late mortality being non-cardiac in 74%. Clinical presentation was a key determinant of 5-year mortality. During follow-up 1 patient suffered a non-fatal myocardial infarction (MI) related to ULMCA in-stent restenosis (ISR), 2 others suffered MI related to non-ULMCA lesions. Definite and probable stent thrombosis occurred in 1 (non-ULMCA stent) and 1, respectively. 3 patients had ULMCA ISR, 14 had non-ULMCA ISR necessitating redo revascularisation.Conclusions: ULMCA PCI is a good treatment modality in patients who cannot undergo CABG. Clinical presentation and downstream disease have a major influence on the 5-year outcome.
      PubDate: Mon, 05 Dec 2016 10:18:26 GMT
       
  • Decision of anticoagulation in patients with atrial fibrillation and low
           CHA2DS2-VASc score remains challenging
    • Authors: poj@peeters-leuven.be
      Abstract: not available
      PubDate: Mon, 05 Dec 2016 10:16:32 GMT
       
  • Catheter ablation for ventricular tachycardia in patients with
           arrhythmogenic right ventricular dysplasia/cardiomyopathy: a systematic
           review and meta-analysis
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: Catheter ablation is commonly performed for ventricular tachycardia (VT) in patients with arrhythmogenic right ventricular dysplasia/cardiomyopathy (ARVD/C). The success rate of VT ablation, either conventional endocardial strategy or recent combined endocardial and epicardial approach, in ARVD/C patients still remains to be determined because of the relatively small sample sizes and various outcomes of previous studies.Methods: PubMed, EMBASE and Cochrane Library were comprehensively searched from their inception until September 2015. All studies have to report acute and long-term efficacy of VT ablation in ARVD/C patients. Data was extracted and analysed according to pre-defined criterions.Results: Eight eligible studies were identified. The mean follow-up duration ranged from 13 to 41 months (median 20 months). The acute efficacy of VT ablation in ARVD/C patients was high, regardless of the ablation strategy. Pooled estimate of acute efficacy was 96% (95% CI: 87%-100%) for endocardial ablation strategy and 98% (95% CI: 91%-100%) for endo-epicardial ablation strategy. Pooled estimate for long-term efficacy with endo-epicardial ablation strategy (82%, 95% CI: 72%-90%) was numerically higher than individual endocardial ablation strategy (63%, 95% CI: 51%-74%).Conclusions: The current evidence suggests that VT ablation in ARVD/C patients is feasible with a high acute and long-term efficacy. Combined endocardial and epicardial ablation strategy is associated with a numerically better outcome of long-term efficacy than individual endocardial ablation strategy.
      PubDate: Mon, 05 Dec 2016 10:15:14 GMT
       
  • A comparison of the European Society of Cardiology, the Seattle and the
           Refined Criteria for interpreting the athlete¯?s ECG in a
           pre-participation screening programme
    • Authors: poj@peeters-leuven.be
      Abstract: Objective: Sudden cardiac death is the main cause of non-traumatic mortality in young athletes. It is mainly caused by asymptomatic structural or electrical heart disease. This indicates the potential need for a pre-participation screening programme. Adding a 12-lead resting ECG to a cardiovascular screening programme increases sensitivity, but reduces specificity. ECG-interpretation criteria have been proposed in order to improve specificity and cost-efficiency. This review evaluates three frequently used criteria and their effect on the sensitivity and specificity of a pre-participation screening programme.Methods and results: This non-systematic review assesses the data of four recent studies comparing the European Society of Cardiology (ESC), the Seattle and the Refined Criteria in a pre-participation screening programme. The sensitivity and specificity of the criteria are evaluated in young (< 35 years) Caucasian, Arabic and black athletes. There is no significant difference in sensitivity between the three criteria (98.1% - 100%). The Refined Criteria are more specific than the ESC and the Seattle criteria. The specificity of the ESC recommendations ranged from 64.8% to 76.6% and the specificity of the Seattle criteria ranged from 87.5% to 88.8%. The Refined Criteria have the highest specificity, 91.4% to 94.0%. Applying the Refined Criteria results in a significant decrease in abnormal ECGs and an improvement of the positive predictive value of an abnormal ECG.Conclusions: Applying the Refined Criteria results in a significant increase in specificity when compared to the ESC and the Seattle criteria, while retaining the same sensitivity. This reduces the amount of abnormal ECGs from 12.7% - 22.3% with the ESC criteria to 1.9% - 6.6% with the Refined Criteria, which in turn greatly decreases the need for further investigations and thus the costs of a pre-participation screening programme.
      PubDate: Mon, 05 Dec 2016 10:12:26 GMT
       
 
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