Subjects -> MEDICAL SCIENCES (Total: 8665 journals)
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PSYCHIATRY AND NEUROLOGY (833 journals)                  1 2 3 4 5 | Last

Showing 1 - 200 of 833 Journals sorted alphabetically
Academic Psychiatry     Full-text available via subscription   (Followers: 31)
Academic Psychiatry and Psychology Journal : APPJ     Open Access   (Followers: 13)
ACS Chemical Neuroscience     Hybrid Journal   (Followers: 23)
Acta Neurochirurgica     Hybrid Journal   (Followers: 7)
Acta Neurologica Belgica     Hybrid Journal   (Followers: 3)
Acta Neurológica Colombiana     Open Access   (Followers: 2)
Acta Neurologica Scandinavica     Hybrid Journal   (Followers: 6)
Acta Neuropathologica     Hybrid Journal   (Followers: 5)
Acta Neuropathologica Communications     Open Access   (Followers: 1)
Acta Neuropsychiatrica     Hybrid Journal   (Followers: 6)
Acta Psychiatrica Scandinavica     Hybrid Journal   (Followers: 44)
Actas Españolas de Psiquiatría     Free   (Followers: 2)
Activitas Nervosa Superior     Hybrid Journal  
ADHD Attention Deficit and Hyperactivity Disorders     Hybrid Journal   (Followers: 28)
ADHD Report The     Full-text available via subscription   (Followers: 12)
Administration and Policy in Mental Health and Mental Health Services Research     Partially Free   (Followers: 21)
Adolescent Psychiatry     Hybrid Journal   (Followers: 12)
Adolescent Research Review     Hybrid Journal   (Followers: 2)
Advances in Alzheimer's Disease     Open Access   (Followers: 16)
Advances in Clinical Neuroscience and Rehabilitation     Free   (Followers: 31)
Advances in Eating Disorders : Theory, Research and Practice     Hybrid Journal   (Followers: 18)
Advances in Mental Health     Hybrid Journal   (Followers: 91)
Advances in Parkinson's Disease     Open Access   (Followers: 1)
Advances in School Mental Health Promotion     Partially Free   (Followers: 12)
African Journal of Neurological Sciences     Open Access  
African Journal of Psychiatry     Full-text available via subscription   (Followers: 3)
Aggression and Violent Behavior     Hybrid Journal   (Followers: 488)
Aggressive Behavior     Hybrid Journal   (Followers: 22)
Aging & Mental Health     Hybrid Journal   (Followers: 38)
Aging, Neuropsychology, and Cognition     Hybrid Journal   (Followers: 51)
AJOB Neuroscience     Hybrid Journal   (Followers: 5)
Aktuelle Neurologie     Hybrid Journal   (Followers: 9)
Alzheimer Disease & Associated Disorders     Hybrid Journal   (Followers: 20)
Alzheimer's & Dementia     Hybrid Journal   (Followers: 60)
Alzheimer's Research & Therapy     Open Access   (Followers: 4)
American Journal of Alzheimer's Disease and Other Dementias     Hybrid Journal   (Followers: 19)
American Journal of Clinical Hypnosis     Hybrid Journal   (Followers: 6)
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics     Hybrid Journal   (Followers: 4)
American Journal of Neuroprotection and Neuroregeneration     Full-text available via subscription   (Followers: 2)
American Journal of Psychiatric Rehabilitation     Hybrid Journal   (Followers: 13)
American Journal of Psychiatry     Full-text available via subscription   (Followers: 239)
Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration     Hybrid Journal   (Followers: 2)
Analitika : Jurnal Magister Psikologi Uma     Open Access  
Annales Médico-psychologiques, revue psychiatrique     Full-text available via subscription   (Followers: 5)
Annals of Behavioral Medicine     Hybrid Journal   (Followers: 15)
Annals of Child Neurology     Open Access   (Followers: 1)
Annals of Clinical and Translational Neurology     Open Access   (Followers: 1)
Annals of Clinical Psychiatry : The official Journal of the American Academy of Clinical Psychiatrists     Hybrid Journal   (Followers: 28)
Annals of General Psychiatry     Open Access   (Followers: 28)
Annals of Indian Academy of Neurology     Open Access   (Followers: 3)
Annals of Indian Psychiatry     Open Access  
Annals of Neurology     Hybrid Journal   (Followers: 61)
Annals of Neurosciences     Open Access   (Followers: 4)
Annals of Psychiatry and Treatment     Open Access   (Followers: 2)
Annual Review of Neuroscience     Full-text available via subscription   (Followers: 57)
Anxiety, Stress & Coping: An International Journal     Hybrid Journal   (Followers: 27)
Aphasiology     Hybrid Journal   (Followers: 55)
Applied Neuropsychology : Adult     Hybrid Journal   (Followers: 46)
Applied Neuropsychology : Child     Hybrid Journal   (Followers: 28)
Archives of Clinical Neuropsychology     Hybrid Journal   (Followers: 33)
Archives of Neuroscience     Open Access   (Followers: 6)
Archives of Psychiatric Nursing     Hybrid Journal   (Followers: 29)
Archives of Suicide Research     Hybrid Journal   (Followers: 9)
Archives of Women's Mental Health     Hybrid Journal   (Followers: 18)
Archivos de Neurociencias     Open Access   (Followers: 3)
Arquivos Brasileiros de Neurocirurgia : Brazilian Neurosurgery     Open Access  
Arquivos de Neuro-Psiquiatria     Open Access  
Art Therapy Online     Open Access   (Followers: 4)
Asia Pacific Journal of Counselling and Psychotherapy     Hybrid Journal   (Followers: 11)
Asian Journal of Psychiatry     Hybrid Journal   (Followers: 2)
ASN Neuro     Open Access   (Followers: 2)
Assessment     Hybrid Journal   (Followers: 17)
Assessment and Treatment of Child Psychopathology and Developmental Disabilities     Full-text available via subscription   (Followers: 4)
Atherosclerosis     Hybrid Journal   (Followers: 13)
Atherosclerosis Supplements     Hybrid Journal   (Followers: 1)
Audiology and Neurotology     Full-text available via subscription   (Followers: 9)
Audiology and Neurotology Extra     Open Access   (Followers: 1)
Australasian Journal of Neuroscience     Open Access   (Followers: 2)
Australasian Psychiatry     Hybrid Journal   (Followers: 18)
Australian & New Zealand Journal of Psychiatry     Hybrid Journal   (Followers: 29)
Autism & Developmental Language Impairments     Open Access   (Followers: 12)
Autism and Developmental Disorders     Open Access   (Followers: 9)
Autism Research     Hybrid Journal   (Followers: 52)
Autism Research and Treatment     Open Access   (Followers: 34)
Autism's Own     Open Access   (Followers: 6)
Autism-Open Access     Open Access   (Followers: 8)
Autonomic Neuroscience     Hybrid Journal   (Followers: 10)
Autonomy, the Critical Journal of Interdisciplinary Autism Studies     Open Access   (Followers: 5)
Avicenna Journal of Neuro Psycho Physiology     Open Access  
Basal Ganglia     Hybrid Journal  
Basic and Clinical Neuroscience     Open Access   (Followers: 9)
Behavior Therapy     Hybrid Journal   (Followers: 54)
Behavioral and Brain Functions     Open Access   (Followers: 3)
Behavioral and Brain Sciences     Hybrid Journal   (Followers: 38)
Behavioral and Cognitive Neuroscience Reviews     Hybrid Journal   (Followers: 26)
Behavioral Healthcare     Full-text available via subscription   (Followers: 8)
Behavioral Medicine     Hybrid Journal   (Followers: 9)
Behavioral Sciences     Open Access   (Followers: 4)
Behavioral Sleep Medicine     Hybrid Journal   (Followers: 14)
Behavioural Brain Research     Hybrid Journal   (Followers: 19)
Behavioural Neurology     Open Access   (Followers: 9)
Behavioural Processes     Hybrid Journal   (Followers: 9)
Biological Psychiatry     Hybrid Journal   (Followers: 53)
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging     Hybrid Journal   (Followers: 11)
Biologically Inspired Cognitive Architectures     Hybrid Journal   (Followers: 2)
Biology of Mood & Anxiety Disorders     Open Access   (Followers: 6)
Biomarkers in Neuropsychiatry     Open Access  
BioMolecular Concepts     Open Access   (Followers: 2)
Bipolar Disorders     Hybrid Journal   (Followers: 11)
BJPsych Advances     Full-text available via subscription   (Followers: 57)
BJPsych Bulletin     Full-text available via subscription   (Followers: 19)
BJPsych International     Open Access   (Followers: 2)
BJPsych Open     Open Access   (Followers: 3)
Blue Books of Neurology     Full-text available via subscription   (Followers: 1)
BMC Neurology     Open Access   (Followers: 22)
BMC Neuroscience     Open Access   (Followers: 17)
BMC Psychiatry     Open Access   (Followers: 38)
Borderline Personality Disorder and Emotion Dysregulation     Open Access   (Followers: 10)
Brain     Hybrid Journal   (Followers: 78)
Brain & Life     Full-text available via subscription   (Followers: 3)
Brain and Behavior     Open Access   (Followers: 15)
Brain and Cognition     Hybrid Journal   (Followers: 38)
Brain and Development     Full-text available via subscription   (Followers: 5)
Brain and Language     Hybrid Journal   (Followers: 68)
Brain and Mind     Hybrid Journal   (Followers: 6)
Brain and Neuroscience Advances     Open Access  
Brain Behavior and Evolution     Full-text available via subscription   (Followers: 9)
Brain Communications     Open Access   (Followers: 2)
Brain Disorders & Therapy     Open Access   (Followers: 1)
Brain Hemorrhages     Open Access   (Followers: 1)
Brain Imaging and Behavior     Hybrid Journal   (Followers: 9)
Brain Impairment     Full-text available via subscription   (Followers: 2)
Brain Informatics     Open Access   (Followers: 1)
Brain Injury     Hybrid Journal   (Followers: 31)
Brain Pathology     Hybrid Journal   (Followers: 5)
Brain Research     Hybrid Journal   (Followers: 26)
Brain Research Bulletin     Hybrid Journal   (Followers: 5)
Brain Sciences     Open Access   (Followers: 5)
Brain Stimulation     Hybrid Journal   (Followers: 8)
Brain Structure and Function     Partially Free   (Followers: 9)
Brain Topography     Hybrid Journal   (Followers: 2)
Brain, Behavior, and Immunity     Hybrid Journal   (Followers: 11)
Brazilian Journal of Pain (BrJP)     Open Access  
British Journal of Mental Health Nursing     Full-text available via subscription   (Followers: 23)
British Journal of Music Therapy     Hybrid Journal   (Followers: 8)
British Journal of Pain     Hybrid Journal   (Followers: 27)
British Journal of Psychiatry     Hybrid Journal   (Followers: 246)
British Journal of Social Psychology     Full-text available via subscription   (Followers: 41)
Canadian Journal of Behavioural Science     Full-text available via subscription   (Followers: 7)
Canadian Journal of Counselling and Psychotherapy / Revue canadienne de counseling et de psychothérapie     Hybrid Journal   (Followers: 10)
Canadian Journal of Neurological Sciences     Full-text available via subscription  
Canadian Journal of Psychiatry     Hybrid Journal   (Followers: 27)
Cannabis and Cannabinoid Research     Hybrid Journal   (Followers: 1)
Case Reports in Neurological Medicine     Open Access   (Followers: 1)
Case Reports in Neurology     Open Access   (Followers: 5)
Case Reports in Psychiatry     Open Access   (Followers: 17)
Cellular and Molecular Life Sciences (CMLS)     Hybrid Journal   (Followers: 5)
Central Nervous System Agents in Medicinal Chemistry     Hybrid Journal   (Followers: 1)
Cephalalgia     Hybrid Journal   (Followers: 8)
Cerebellum & Ataxias     Open Access   (Followers: 1)
Cerebral Cortex     Hybrid Journal   (Followers: 56)
Cerebrovascular Diseases     Full-text available via subscription   (Followers: 3)
Cerebrovascular Diseases Extra     Open Access  
Child and Adolescent Psychiatry and Mental Health     Open Access   (Followers: 28)
Child Neurology Open     Open Access   (Followers: 5)
Child Psychiatry & Human Development     Hybrid Journal   (Followers: 12)
Chinese Neurosurgical Journal     Open Access  
Chronic Stress     Open Access  
Ciencia Cognitiva     Open Access   (Followers: 3)
Clínica e Investigación en Arteriosclerosis     Full-text available via subscription  
Clinical and Experimental Neuroimmunology     Hybrid Journal   (Followers: 1)
Clinical and Translational Neuroscience     Open Access  
Clinical EEG and Neuroscience     Hybrid Journal   (Followers: 6)
Clinical Journal of Pain     Hybrid Journal   (Followers: 19)
Clinical Medicine Insights : Psychiatry     Open Access   (Followers: 10)
Clinical Neurology and Neurosurgery     Hybrid Journal   (Followers: 16)
Clinical Neuropathology     Full-text available via subscription   (Followers: 1)
Clinical Neuropharmacology     Hybrid Journal   (Followers: 4)
Clinical Neurophysiology     Full-text available via subscription   (Followers: 13)
Clinical Neurophysiology Practice     Open Access  
Clinical Neuropsychiatry     Open Access   (Followers: 2)
Clinical Practice & Epidemiology in Mental Health     Open Access   (Followers: 1)
Clinical Psychological Science     Hybrid Journal   (Followers: 12)
CNS & Neurological Disorders - Drug Targets     Hybrid Journal   (Followers: 3)
CNS Spectrums     Hybrid Journal   (Followers: 3)
Cognition     Hybrid Journal   (Followers: 231)
Cognitive and Behavioral Neurology     Hybrid Journal   (Followers: 10)
Cognitive and Behavioral Practice     Hybrid Journal   (Followers: 13)
Cognitive Neurodynamics     Hybrid Journal   (Followers: 2)
Cognitive Neuropsychiatry     Hybrid Journal   (Followers: 1)
Cognitive Neuropsychology     Hybrid Journal   (Followers: 40)
Cognitive Neuroscience     Hybrid Journal   (Followers: 29)
Cognitive Therapy and Research     Hybrid Journal   (Followers: 7)
Cognitive, Affective, & Behavioral Neuroscience     Full-text available via subscription   (Followers: 24)
Community Mental Health Journal     Hybrid Journal   (Followers: 17)
Comprehensive Psychiatry     Open Access   (Followers: 13)
Computational Brain & Behavior     Hybrid Journal  
Computational Psychiatry     Open Access   (Followers: 2)
Consciousness and Cognition     Hybrid Journal   (Followers: 39)
Contemporary Neurosurgery     Full-text available via subscription   (Followers: 4)

        1 2 3 4 5 | Last

Similar Journals
Journal Cover
Archives of Women's Mental Health
Journal Prestige (SJR): 1.274
Citation Impact (citeScore): 3
Number of Followers: 18  
  Hybrid Journal Hybrid journal (It can contain Open Access articles)
ISSN (Print) 1435-1102 - ISSN (Online) 1434-1816
Published by Springer-Verlag Homepage  [2626 journals]
  • The ageing body: contributing attitudinal factors towards perceptual body
           size estimates in younger and middle-aged women
    • Abstract: Abstract Over-estimation of body size, a core feature of eating disorders (EDs), has been well-documented both in young healthy and ED individuals. Yet, evidence that altered body perception might also affect older women is limited. Here, we examined whether attitudinal components of body image (i.e. the feelings an individual has about their body size and shape) might affect perceived actual and ideal body shape self-estimates in midlife, similarly to younger women. Thirty-two younger (mean age, 24.22 years) and 33 middle-aged (mean age, 53.79 years) women took part to a computerized body perception assessment of perceived, actual and ideal aspects of body image. Body mass index (BMI), societal and interpersonal aspects of appearance ideals, measured by means of Sociocultural Attitudes towards Appearance Questionnaire (SATAQ-4), and assessment of body uneasiness and concerns for specific body parts, measured by Body Uneasiness Test (BUT-A/B) scales, were also investigated. Younger and middle-aged women with larger BMI showed greater discrepancy in perceptual distortions from their perceived actual body size. However, middle-aged women with greater body part concerns overestimated their perceived body size, as opposed to younger women who were almost accurate. Unlike middle-aged women, younger women with higher body part concerns desired slimmer ideal body image than their perceived actual. Results suggest that distortions in the perceived actual and ideal body size self-estimates of younger and middle-aged women are best explained by a combination of BMI, body part concerns and the particular age group to which a participant belonged. In the future, a personalized approach for the assessment of women’s perceptions and concerns of specific body areas during lifespan should be adopted.
      PubDate: 2020-06-19
  • Predictors of response to antidepressants in women with postpartum
           depression: a systematic review
    • Abstract: Abstract Antidepressants are the mainstay of drug treatment for moderate or severe postpartum depression. Knowledge of predictors of response could help optimize treatment and reduce the adverse consequences of postpartum depression. The purpose of this systematic review was to ascertain predictors of response or remission to antidepressant treatment in women with postpartum depression. The electronic databases of MEDLINE/PubMed, PsycINFO, CINAHL, Cochrane Database of Systematic Reviews, and Evidence-based Medicine Reviews were searched through December 2019. The search was limited to studies published in the English language. Reference lists of articles that met the inclusion criteria were also searched. We identified some predictors of response and remission that could potentially assist in the optimization of drug treatment of postpartum depression; however, caution is needed to apply these findings in clinical practice due to the heterogeneous nature of postpartum depression. The results of our review highlight the urgent need to identify predictors of response, non-response, or remission to antidepressants in women with postpartum depression.
      PubDate: 2020-06-16
  • Demonstrated health care cost savings for women: findings from a community
           health worker intervention designed to address depression and unmet social
    • Abstract: Abstract To evaluate the impact of a community health worker intervention (CHW) (referred to as Personalized Support for Progress (PSP)) on all-cause health care utilization and cost of care compared with Enhanced Screening and Referral (ESR) among women with depression. A total of 223 patients (111 in PSP and 112 in ESR randomly assigned) from three women’s health clinics with elevated depressive symptoms were enrolled in the study. Their electronic health records were queried to extract all-cause health care encounters along with the corresponding billing information 12 months before and after the intervention, as well as during the first 4-month intervention period. The health care encounters were then grouped into three mutually exclusive categories: high-cost (> US$1000 per encounter), medium-cost (US$201–$999), and low-cost (≤ US$200). A difference-in-difference analysis of mean total charge per patient between PSP and ESR was used to assess cost differences between treatment groups. The results suggest the PSP group was associated with a higher total cost of care at the baseline; taking this baseline difference into account, the PSP group was associated with lower mean total charge amounts (p = 0.008) as well as a reduction in the frequency of high-cost encounters (p < 0.001) relative to the ESR group during the post-intervention period. Patient-centered interventions that address unmet social needs in a high-cost population via CHW may be a cost-effective approach to improve quality of care and patient outcomes.
      PubDate: 2020-06-16
  • The mental health of women with polycystic ovary syndrome: a systematic
           review and meta-analysis
    • Abstract: Abstract Polycystic ovary syndrome (PCOS) has been proposed to be associated with several mental health problems, including anxiety, depression, diminished sexual satisfaction, and lowered health-related quality of life, etc. A systematic review and meta-analysis of published literature was conducted comparing the mental health of women with and without PCOS. Ten English and Chinese databases were searched up to 12/31/2018. Random-effects models were introduced, and subgroup analysis, sensitivity test, and meta-regression were carried out to determine the source for heterogeneity among studies. Forty-six studies, including 30,989 participants (9265 women with PCOS and 25,638 controls), were qualified for review according to the inclusion criteria. Twenty-eight studies reported depression symptoms, 22 studies were on anxiety, 16 studies showed quality of life (QoL) status, 12 studies were about sexual dysfunction, five on emotional distress, four on binge eating, and four on somatization. Women with PCOS reported significantly higher depression (SMD = 0.64; 95% CI 0.50–0.78), anxiety (SMD = 0.63; 95% CI 0.50–0.77), lower QoL (SMD = − 0.55; 95% CI −0.69 to −0.40), and not significant sexual dysfunction (SMD = − 0.24; 95% CI − 0.49 to 0.01). Studies from different countries, adopting various diagnosis criteria, using diverse instruments, as well as in different years, have reported heterogenetic results. Women with PCOS in China reported a larger effect size of depression and anxiety than patients from other countries. The results of this study have indicated that women with PCOS suffer from depression, anxiety, and experience a lower quality of life, whereas their sexual function is not distinct from that of healthy women. Psychological health care interventions for women with PCOS were addressed.
      PubDate: 2020-06-09
  • Correction to: Testing competing mediators of the association between
           pre-conception maternal depression and child health-related quality of
           life: the MatCH study
    • Abstract: The current sentence is in the discussion (sub-section The role of pre-conception maternal depression) and reads: “Pre-conception treatment of mental health issues is also associated with substantial savings in health care costs (Chojenta et al., 2018).”
      PubDate: 2020-06-01
  • The oxytocinergic system in PTSD following traumatic childbirth:
           endogenous and exogenous oxytocin in the peripartum period
    • Abstract: Abstract Birth experiences can be traumatic and may give rise to PTSD following childbirth (PTSD-FC). Peripartum neurobiological alterations in the oxytocinergic system are highly relevant for postpartum maternal behavioral and affective adaptions like bonding and lactation but are also implicated in the response to traumatic events. Animal models demonstrated that peripartum stress impairs beneficial maternal postpartum behavior. Early postpartum activation of the oxytocinergic system may, however, reverse these effects and thereby prevent adverse long-term consequences for both mother and infant. In this narrative review, we discuss the impact of trauma and PTSD-FC on normal endogenous oxytocinergic system fluctuations in the peripartum period. We also specifically focus on the potential of exogenous oxytocin (OT) to prevent and treat PTSD-FC. No trials of exogenous OT after traumatic childbirth and PTSD-FC were available. Evidence from non-obstetric PTSD samples and from postpartum healthy or depressed samples implies restorative functional neuroanatomic and psychological effects of exogenous OT such as improved PTSD symptoms and better mother-to-infant bonding, decreased limbic activation, and restored responsiveness in dopaminergic reward regions. Adverse effects of intranasal OT on mood and the increased fear processing and reduced top-down control over amygdala activation in women with acute trauma exposure or postpartum depression, however, warrant cautionary use of intranasal OT. Observational and experimental studies into the role of the endogenous and exogenous oxytocinergic system in PTSD-FC are needed and should explore individual and situational circumstances, including level of acute distress, intrapartum exogenous OT exposure, or history of childhood trauma.
      PubDate: 2020-06-01
  • Association between maternal and child mental health among US Latinos:
           variation by nativity, ethnic subgroup, and time in the USA
    • Abstract: Abstract Few studies have examined the association between maternal and youth mental health among US Latinos, or its variation by nativity, country of origin, ethnic subgroup, and time in the mainland US. Using 2007–2014 Medical Expenditure Panel Survey data linking Latino youth (N = 15,686 aged 5–17 years) and their mothers, we estimated multivariate models of the relationship between probable maternal mental illness (a composite of measures) and youth mental health impairment (Columbia Impairment Scale). Children of mothers with probable mental illness were more than three times as likely to have impairment as children of mothers without mental illness (p < 0.01). In adjusted models, there was an 8.5-point (95% CI 5.1, 11.8) increased prevalence of child impairment associated with mother’s probable mental illness among mainland US–born youth and mothers and a 6.0-point (95% CI 3.7, 8.3) increased prevalence among US-born youth of foreign/island-born mothers. There was no significant difference in the prevalence of youth impairment associated with maternal mental illness when both youth and mother were born outside of the mainland US. For the Puerto Rican subgroup, the association between maternal and youth mental health was greatest among island-born mothers and mainland US–born youth; for the Mexican subgroup, the link was strongest among US-born mothers and youth. While there were large point differences between those groups, the difference was not statistically significant. This study suggests a protective effect of island/foreign-born nativity on symptom association between Latino mothers and children. Considerations for future research and practice stemming from this finding are discussed.
      PubDate: 2020-06-01
  • Maternal behavioral health symptom profiles in early family life:
           complexity and context
    • Abstract: Abstract Behavioral health problems affect at least 15% of mothers, but few studies have examined how different problems cluster together. Characterizing symptom profiles and their correlates early in the family life cycle can extend existing understanding beyond that provided by studies based on single problems. Mothers in the Fragile Families and Child Wellbeing study, a national birth cohort of racially diverse and mostly unmarried mothers (N = 4205), reported depression, anxiety, and substance dependence symptoms. Latent class analysis (LCA) identified mothers’ symptom profiles in their children’s third year. We explored associations between symptom profiles and demographics, reproductive health outcomes, functional limitations, and postpartum behavioral health. LCA identified five profiles: (1) Depression only (14.5% of sample), (2) Severe depression and anxiety (5.3%), (3) Anxiety only (2.2%), (4) Depression and substance use (1.4%), and (5) Currently symptom free (76.6%). Depressive symptoms were more moderate when co-occurring with substance dependence and more severe when co-occurring with anxiety. Postpartum depression, postpartum anxiety, and smoking during pregnancy were the most robust correlates of being symptomatic in year 3. Mothers in the “Severe depression and anxiety” group were more likely to be in that profile if they reported functional impairment and/or relationship dissolution. Mothers in the “Depression only” profile were more likely to have higher parity and/or functional impairment. A quarter of mothers of young children had significant behavioral health symptoms, with most reporting depression symptoms. Psychosocial and physical health factors in the pregnancy and postpartum periods were associated with future symptoms, warranting obstetrician and pediatrician attention.
      PubDate: 2020-06-01
  • Associations of perceived prenatal stress and adverse pregnancy outcomes
           with perceived stress years after delivery
    • Abstract: Abstract Maternal stress is a risk factor for adverse pregnancy outcomes (APOs). This study evaluates the associations of prenatal stress and APOs with maternal stress years after pregnancy. The 10-item Perceived Stress Scale (PSS) (0–40 range) was completed in the first and third trimesters, and 2–7 years after delivery among a subsample (n = 4161) of nulliparous women enrolled at eight US medical centers between 2010 and 2013 in a prospective, observational cohort study. Demographics, medical history, and presence of APOs (gestational diabetes (GDM), hypertensive disorders of pregnancy (HDP), preeclampsia (PE), and medically indicated or spontaneous preterm birth (miPTB, sPTB)) were obtained. The associations of prenatal PSS and the presence of APOs with PSS scores years after delivery were estimated using multivariable linear regression. Mean PSS scores were 12.5 (95% CI 12.3, 12.7) and 11.3 (95% CI 11.1, 11.5) in the first and third trimesters respectively and 14.9 (95% CI 14.7, 15.1) 2–7 years later, an average increase of 2.4 points (95% CI 2.2, 2.6) from the start of pregnancy. Regressing PSS scores after delivery on first-trimester PSS and PSS increase through pregnancy showed positive associations, with coefficients (95% CI) of 2.8 (2.7, 3.0) and 1.5 (1.3, 1.7) per 5-point change, respectively. Adding APO indicator variables separately showed higher PSS scores for women with HDP (0.7 [0.1, 1.3]), PE (1.3 [0.6, 2.1]), and miPTB (1.3 [0.2, 2.4]), but not those with GDM or sPTB. In this geographically and demographically diverse sample, prenatal stress and some APOs were positively associated with stress levels 2–7 years after pregnancy. Registration number NCT02231398.
      PubDate: 2020-06-01
  • Obstetric and neonatal outcomes of clozapine exposure in pregnancy: a
           consecutive case series
    • Abstract: Abstract Clozapine is an effective antipsychotic that can lead to symptom resolution and functional recovery in patients with schizophrenia. Its available pregnancy safety data remain limited, which presents a challenge for clinicians managing women of reproductive age on clozapine. We retrospectively studied a consecutive case series of nine pregnancies where there was clozapine exposure. Our case series demonstrates that pregnant women on clozapine treatment can remain stable psychiatrically, but are vulnerable obstetrically, with high rates of obesity and gestational diabetes. Their babies also have poor neonatal adjustment, often requiring neonatal resuscitation. Furthermore, we report on clozapine-related side effects, changes in clozapine levels during pregnancy as well as variation in foetal wellbeing monitoring. These findings have implications for pregnancy care for women taking clozapine and require further exploration.
      PubDate: 2020-06-01
  • Worrying in the wings' Negative emotional birth memories in mothers
           and fathers show similar associations with perinatal mood disturbance and
           delivery mode
    • Abstract: Abstract Negative birth experiences can lead to symptoms of post-traumatic stress disorder in new mothers but have received much less attention in new fathers. A sample of 314 first-time expectant couples rated their symptoms of anxiety and depression in the third trimester and at 4-month post birth (227 vaginal delivery, 87 caesarean section), when they also completed the emotional memories subscale of the BirthMARQ (Foley et al. BMC Pregnancy Childbirth, 14, 211, 2014). We first examined mode of delivery (vaginal birth versus caesarean section) as a predictor of mothers’ and fathers’ BirthMARQ scores. Next, we used actor-partner interdependence model (APIM) to investigate intra- and interpersonal associations between birth experiences and maternal/paternal latent factors for antenatal and postnatal depression/anxiety. Reports of negative birth experiences were more common for mothers than fathers and for parents of babies born by caesarean section than by vaginal delivery. Within-couple agreement was moderately strong and, for both parents at both time-points, individual differences in negative birth memories were associated with symptoms of depression and anxiety. Negative birth memories also played a mediating role in the association between birth via caesarean section and reduced postnatal maternal wellbeing. Given the striking similarities between mothers and fathers in links between birth experiences and wellbeing, our findings highlight the need for partner-inclusive intervention strategies.
      PubDate: 2020-06-01
  • Early life adversity and depressive symptoms predict cortisol in pregnancy
    • Abstract: Abstract Evidence suggests that exposure to early life adversity (ELA) programs the hypothalamic-pituitary-adrenal (HPA) axis to influence responses to later adversity and predisposes women to depression. However, few studies have examined whether ELA moderates the HPA cortisol response to adulthood adversity and depressive symptoms in pregnant women. The aims of this study were to determine (a) whether ELA, adulthood adversity, and depressive symptoms differentially predict patterns of cortisol and (b) whether ELA moderates the relationship of adulthood adversity or depressive symptoms to cortisol. This was a descriptive, cross-sectional study of pregnant women (N = 58, mean = 26.5 weeks gestation). Participants completed the Stress and Adversity Inventory and Edinburgh Depression Scale and collected salivary cortisol five times per day for 3 days to assess cortisol awakening response (CAR), diurnal cortisol slope, and cortisol area under the curve (AUC). ELA predicted a larger CAR, while depressive symptoms predicted a blunted CAR and higher cortisol AUC. Adulthood adversity predicted a blunted CAR and steeper diurnal slope, but only in women with high ELA. ELA also moderated the effect of depressive symptoms on diurnal slope. Early adversity and depressive symptoms appear to have significant effects on the HPA axis during pregnancy, with early adversity also moderating effects of depressive symptoms and adulthood adversity on cortisol regulation. Early adversity may be an important factor in identifying unique HPA phenotypes and risk for HPA axis dysregulation in pregnancy.
      PubDate: 2020-06-01
  • Longitudinal assessment of symptoms of postpartum mood disorder in women
           with and without a history of depression
    • Abstract: Abstract The main objective of the present study was to report the incidence, recurrence, prevalence, and course of depressive symptoms during the transition from late pregnancy to the postpartum period in healthy women with and without a history of depression. The study also aimed to examine the predictive value of a history of premenstrual syndrome (PMS)/premenstrual dysphoric disorder (PMDD) for peripartum depressive symptoms. A sample of 687 healthy women with (n = 192) and without (n = 495) a history of depression were included in the present analyses. Maternal depressive symptoms were assessed during late pregnancy, 1–2 weeks postpartum, and 4–6 weeks postpartum using the German version of the Edinburgh Postnatal Depression Scale. PMS/PMDD was assessed retrospectively using the German version of the Premenstrual Symptoms Screening Tool. Women with a history of depression were twice more likely to show peripartum depressive symptoms than women without a history of depression. A history of symptoms of PMS/PMDD prior to the current pregnancy was associated with increased odds of peripartum depressive symptoms (p values < .05). Peripartum depressive symptoms are highly prevalent, especially in women with a history of depression and co-existing symptoms of PMS/PMDD. Screening for depression in the antenatal period is highly recommended, particularly for individuals with previous PMS/PMDD or a history of depression.
      PubDate: 2020-06-01
  • Sex differences in symptomatology of psychosis-risk patients and in
           prediction of psychosis
    • Abstract: Abstract Sex differences may be important for understanding underlying pathophysiological mechanisms and developing effective preventions and treatments of mental disorders. Despite sex differences in the onset of psychosis, patients at clinical high risk for psychosis (CHR) are underinvestigated for sex effects, especially with respect to models for prediction of conversion to psychosis. We studied psychopathological sex differences in referrals to a German early detection service and in its subgroup of converters and examined sex-specific psychopathological prediction models. In 152 male and 90 female referrals (88% at CHR; 35% converters), symptoms assessed with the Structured Interview for Psychosis-Risk Syndromes were investigated for sex differences using effect sizes. Sex-specific prediction models of psychosis were separately generated using Cox regressions with a LASSO operator. We found different small sex effects (0.10 < Rosenthal’s r < 0.30) in the referral and in the converter sample. In the referral sample, exclusively, males showed more pronounced symptoms (all negative symptoms incl. reduced stress tolerance, grandiosity, and disorganized communication); in converters, females experienced more pronounced perceptual abnormalities, bizarre thinking, and odd behaviors, while males expressed and experienced emotions to a lower degree. Furthermore, sexes differed in psychosis-predictive symptoms: “suspiciousness” and “disorganized communication” were prominent in prediction of psychosis in males, whereas “trouble with focus and attention” was so in females. While most sex differences in patients attending an early detection service seem to reflect general differences that are not specifically related to psychosis, others might be psychosis-specific. These results can inform the development of more individualized and effective interventions for CHR patients based on more precise sex-specific prediction models.
      PubDate: 2020-06-01
  • The relationship between gender and life satisfaction: analysis across
           demographic groups and global regions
    • Abstract: Abstract This study sought to examine gender differences in life satisfaction globally and across demographic groups. The grouping variables included age, global region, marital status, employment status, education, and income. A sample of 1,801,417 participants across 166 countries was drawn from the Gallup World Poll. Given the hierarchical nature of the data, multi-level modeling was used for data analysis. Gender differences in life satisfaction were found to be significant yet small. Women reported higher levels of life satisfaction than men across all income, education, and employment groups. The direction of gender differences in life satisfaction was inconsistent across age and regional groups. Men scored higher than women only over the age of about 63, and in sub-Saharan Africa. Despite the less favorable objective conditions for women globally, women were found to be more satisfied with their lives than men across most of the groups we studied. It is hoped that the present results can be used to inform research and practice aiming to identify vulnerable female groups and to optimize the well-being of women globally.
      PubDate: 2020-06-01
  • Poor sleep and emotion dysregulation mediate the association between
           depressive and premenstrual symptoms in young adult women
    • Abstract: Abstract A large portion of reproductive-aged women report experiencing distressing premenstrual symptoms. These symptoms can be exacerbated by concurrent mood problems and contribute to long-term depressive risk. However, difficulty sleeping and regulating emotional responses are also associated with the premenstrual phase and represent additional, well-established risk factors for depression. The aim of this study was to investigate whether habitual sleep problems and emotion regulation strategies serve to mediate the relationship between mood and premenstrual symptoms in non-treatment–seeking young women. Participants included 265 adult women between the ages of 18 and 25 who provided retrospective self-reports of depressive symptoms, habitual sleep quality, and premenstrual symptoms for the past month. Trait-based difficulties in regulating emotions were also assessed. Greater depressive symptoms significantly predicted greater premenstrual symptoms and both poor sleep and ineffective emotion regulation were shown to mediate this relationship. Poor sleep may enhance experience of premenstrual symptoms via its well-established impact on physical, cognitive, and/or affective functioning. Similarly, an inability to effectively regulate emotional responses in general may exacerbate experience or perception of somatic and mood symptoms during the premenstrual period, contributing to mood disturbances and risk. Findings require replication in future studies using prospective designs and more diverse samples of women.
      PubDate: 2020-06-01
  • Interaction between the functional SNP rs2070951 in NR3C2 gene and high
           levels of plasma corticotropin-releasing hormone associates to postpartum
    • Abstract: Abstract Postpartum depression (PPD) is a common mood disorder that occurs after delivery with a prevalence of approximately 10%. Recent reports have related placental corticotropin-releasing hormone (pCRH) to postpartum depressive symptoms. The aim of this study was to determine whether pCRH, ACTH, and cortisol (measured 48 h after delivery) and glucocorticoid and mineralocorticoid receptor genotypes (NR3C1 and NR3C2) and their interaction are associated with PPD. A longitudinal 32-week prospective study of five hundred twenty-five Caucasian depression-free women that were recruited from obstetric units at two Spanish general hospitals immediately after delivery. Of the women included in the sample, forty-two (8%) developed PPD. A strong association between PPD and the interaction between the pCRH and NR3C2 rs2070951 genotype was observed. The mean level of pCRH in rs2070951GG carriers with PPD was 56% higher than the mean in the CG and CC genotype groups (P < 0.00005). Carriers of the rs2070951GG genotype with high levels of pCRH had a higher risk of developing PPD (OR = 1.020, 95% CI 1.007–1.034, P = 0.002). This association remained even after controlling for variables such as neuroticism, obstetric complications and the number of stressful life events during pregnancy. There is an important interaction between pCRH 48 h postpartum and the NR3C2 rs2070951GG genotype. This interaction moderately associates with the presence of PPD. These results may open a new line of research and, if confirmed in other settings, will help to identify better risk predictors and the treatment for PPD.
      PubDate: 2020-06-01
  • Transdermal estradiol for postpartum depression: results from a pilot
           randomized, double-blind, placebo-controlled study
    • Abstract: Abstract Postpartum depression (PPD) is a common complication following delivery, though evidence-based treatment options are limited. This study explores the feasibility and efficacy of outpatient PPD treatment with transdermal estradiol (TE). In a pilot, double-blind, placebo-controlled trial, women with PPD were randomized to receive transdermal 17β-estradiol (100 mcg/day) or placebo patch. Over 6 weeks, women completed weekly ratings on the Beck Depression Inventory (BDI), Edinburgh Postnatal Depression Scale (EPDS), and Hamilton Depression Scale (HAM-D). Primary outcome measures were treatment response (> 50% decrease from baseline BDI) and remission (BDI < 10) at 6 weeks, and secondary outcome measures included severity on all scales at weeks 3 and 6. Of 12 recruited women, 6 received TE and 6 received placebo. By week 6, 5 women receiving TE responded to treatment and 4 showed symptom remission, compared to 2 responders and 1 remitter in the placebo group. This difference was not significant (p = 0.24). In a mixed-model of BDI ratings, TE was associated with a 9.2 point decrease at 3 weeks (95%CI − 19.5 to + 1.0, p = 0.074) and a 10.5 point decrease at 6 weeks (95%CI − 21.0–0.0, p = 0.049) compared to placebo, though these differences did not survive multiple comparisons correction. Analogous effects were found for HAM-D but not EPDS scores. Interestingly, no significant difference in plasma estradiol levels existed between groups. We were unable to demonstrate a significant therapeutic benefit of TE compared with placebo in PPD. Although limited by under-recruitment and loss to follow-up, our results suggest TE is a feasible option for outpatient PPD management, with preliminary evidence (based on secondary outcomes) for efficacy. Therapeutic effects may be seen as early as 3 weeks and may not directly depend on peripheral measures of estradiol.
      PubDate: 2020-06-01
  • COVID outbreak is changing our practices of perinatal psychiatry
    • PubDate: 2020-05-28
  • Are we overlooking obsessive-compulsive disorder during and after
           pregnancy' Some arguments for a peripartum onset specifier
    • Abstract: Abstract The peripartum period appears to be a potent trigger of obsessive-compulsive disorder in women; however, due to the lack of awareness and routine screening, women with obsessive-compulsive disorder may be at risk of under- or misdiagnosis. Unfortunately, the missed diagnosis or misdiagnosis can have serious consequences including symptom persistence, compromised ability to care for the newborn, poor quality of life and unnecessary reporting of the mother to child protective services. It is argued that future iterations of the DSM consider expanding the scope of the peripartum onset specifier to include obsessive-compulsive disorder to increase its detection, diagnosis and management.
      PubDate: 2020-05-26
School of Mathematical and Computer Sciences
Heriot-Watt University
Edinburgh, EH14 4AS, UK
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