Subjects -> MEDICAL SCIENCES (Total: 8697 journals)
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MEDICAL SCIENCES (2419 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 3)
3D Printing in Medicine     Open Access   (Followers: 5)
4 open     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 6)
AAS Open Research     Open Access   (Followers: 2)
ABCS Health Sciences     Open Access   (Followers: 8)
Abia State University Medical Students' Association Journal     Full-text available via subscription   (Followers: 3)
AboutOpen     Open Access  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 50)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access  
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Científica Estudiantil     Open Access  
Acta Facultatis Medicae Naissensis     Open Access   (Followers: 1)
Acta Herediana     Open Access  
Acta Informatica Medica     Open Access   (Followers: 2)
Acta Medica (Hradec Králové)     Open Access  
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta Medica International     Open Access  
Acta medica Lituanica     Open Access   (Followers: 1)
Acta Medica Marisiensis     Open Access   (Followers: 1)
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access   (Followers: 1)
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 3)
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 8)
Acupuncture and Natural Medicine     Open Access  
Addiction Science & Clinical Practice     Open Access   (Followers: 9)
Addictive Behaviors Reports     Open Access   (Followers: 9)
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / Health Sciences Journal of Adıyaman University     Open Access   (Followers: 1)
Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi     Open Access   (Followers: 1)
Advanced Biomedical Research     Open Access  
Advanced Health Care Technologies     Open Access   (Followers: 10)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 9)
Advanced Therapeutics     Hybrid Journal   (Followers: 1)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 7)
Advances in Cell and Gene Therapy     Hybrid Journal   (Followers: 1)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 27)
Advances in Clinical Radiology     Full-text available via subscription   (Followers: 3)
Advances in Life Course Research     Hybrid Journal   (Followers: 11)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Medical Education and Practice     Open Access   (Followers: 32)
Advances in Medical Ethics     Open Access   (Followers: 5)
Advances in Medical Research     Open Access   (Followers: 2)
Advances in Medical Sciences     Hybrid Journal   (Followers: 10)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Medicine     Open Access   (Followers: 3)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 5)
Advances in Molecular Oncology     Open Access   (Followers: 2)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7)
Advances in Parkinson's Disease     Open Access   (Followers: 2)
Advances in Phytomedicine     Full-text available via subscription   (Followers: 1)
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 21)
Advances in Regenerative Medicine     Open Access   (Followers: 4)
Advances in Skeletal Muscle Function Assessment     Open Access  
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Traditional Medicine     Hybrid Journal   (Followers: 8)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 15)
Advances in Virus Research     Full-text available via subscription   (Followers: 6)
Advances in Wound Care     Hybrid Journal   (Followers: 14)
Aerospace Medicine and Human Performance     Full-text available via subscription   (Followers: 13)
African Health Sciences     Open Access   (Followers: 5)
African Journal of Biomedical Research     Open Access   (Followers: 1)
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 4)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 3)
African Journal of Thoracic and Critical Care Medicine     Open Access  
African Journal of Trauma     Open Access   (Followers: 1)
Afrimedic Journal     Open Access   (Followers: 3)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 9)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
AJSP: Reviews & Reports     Hybrid Journal   (Followers: 1)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 6)
Al-Azhar Assiut Medical Journal     Open Access   (Followers: 2)
Al-Qadisiah Medical Journal     Open Access   (Followers: 1)
Alerta : Revista Científica del Instituto Nacional de Salud     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 3)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 2)
Althea Medical Journal     Open Access   (Followers: 2)
American Journal of Biomedical Engineering     Open Access   (Followers: 15)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 7)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 4)
American Journal of Clinical Medicine Research     Open Access   (Followers: 8)
American Journal of Family Therapy     Hybrid Journal   (Followers: 10)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 7)
American Journal of Managed Care     Full-text available via subscription   (Followers: 13)
American Journal of Medical Case Reports     Open Access   (Followers: 3)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 5)
American Journal of Medicine     Hybrid Journal   (Followers: 50)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access   (Followers: 3)
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 11)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 6)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 5)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 7)
Anatolian Clinic the Journal of Medical Sciences     Open Access  
Anatomica Medical Journal     Open Access  
Anatomical Science International     Hybrid Journal   (Followers: 3)
Anatomical Sciences Education     Hybrid Journal   (Followers: 2)
Anatomy     Open Access   (Followers: 3)
Anatomy Research International     Open Access   (Followers: 4)
Androgens : Clinical Research and Therapeutics     Open Access  
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Ankara Medical Journal     Open Access   (Followers: 2)
Ankara Üniversitesi Tıp Fakültesi Mecmuası     Open Access  
Annales de Pathologie     Full-text available via subscription  
Annales des Sciences de la Santé     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 2)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 3)
Annals of Bioanthropology     Open Access   (Followers: 5)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 19)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 4)
Annals of Clinical Hypertension     Open Access  
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 15)
Annals of Family Medicine     Open Access   (Followers: 18)
Annals of Health Research     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 7)
Annals of Medicine and Surgery Case Reports     Open Access   (Followers: 1)
Annals of Medicine and Surgery Protocols     Open Access   (Followers: 1)
Annals of Microbiology     Hybrid Journal   (Followers: 13)
Annals of Musculoskeletal Medicine     Open Access   (Followers: 2)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Rehabilitation Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the College of Medicine, Mosul     Open Access   (Followers: 1)
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annals of the RussianAacademy of Medical Sciences     Open Access   (Followers: 1)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 5)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 25)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Reports     Open Access   (Followers: 1)
Antibody Technology Journal     Open Access   (Followers: 1)
Antibody Therapeutics     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 2)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 5)
Applied Clinical Research, Clinical Trials and Regulatory Affairs     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 14)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arabian Journal of Scientific Research / المجلة العربية للبحث العلمي     Open Access   (Followers: 1)
Archive of Biomedical Science and Engineering     Open Access   (Followers: 1)
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access   (Followers: 1)
Archives Medical Review Journal / Arşiv Kaynak Tarama Dergisi     Open Access  
Archives of Asthma, Allergy and Immunology     Open Access  
Archives of Clinical Hypertension     Open Access   (Followers: 2)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 5)
Archives of Medicine and Surgery     Open Access   (Followers: 1)
Archives of Organ Transplantation     Open Access   (Followers: 2)
Archives of Preventive Medicine     Open Access   (Followers: 3)
Archives of Pulmonology and Respiratory Care     Open Access   (Followers: 2)
Archives of Renal Diseases and Management     Open Access   (Followers: 2)
Archives of Trauma Research     Open Access   (Followers: 4)
Archivos de Medicina (Manizales)     Open Access   (Followers: 1)
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access   (Followers: 1)
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access   (Followers: 1)
Ars Medica : Revista de Ciencias Médicas     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Hybrid Journal   (Followers: 19)
Arterial Hypertension     Open Access   (Followers: 1)
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 20)
Artificial Organs     Hybrid Journal   (Followers: 1)
ASHA Leader     Open Access   (Followers: 6)
Asia Pacific Family Medicine Journal     Open Access   (Followers: 4)
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 13)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access   (Followers: 1)

        1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
Annals of Health Research
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2476-8642 - ISSN (Online) 2536-6149
Published by Olabisi Onabanjo University Teaching Hospital Homepage  [1 journal]
  • The pattern of crisis calls to a suicide telephone helpline service in
           Nigeria

    • Authors: RE Ogbolu, BO Oyatokun, K Ogunsola, TA Adegbite, T Tade, O Olafisoye, OF Aina
      Pages: 246 - 257
      Abstract: Background: Suicide is the deliberate killing of oneself. Although it is preventable, suicide accounts for over 800,000 global deaths annually. There is the need to scale-up prevention strategies, and one of these strategies is the provision of suicide telephone helplines. Objectives: To describe the pattern of calls received by a suicide telephone helpline and the types of intervention provided in a Nigerian facility. Methods: This was a descriptive study of the first 100 completed calls received on a 24-hour suicide telephone helpline service by trained responders. Results: All the calls emanated from 14 states of the federation, with the majority (83.0%) from the Southern parts of the country. The reasons for the telephone calls varied from crisis situations (47.0%) to telephone number-verification (27.0%), mental health information (20.0%), and others (6.0%). The mean age of the crisis -situation callers was 25.8 years, with a slight female preponderance (53.2%); most were single in marital status (68.1%) and unemployed (70.2%). A majority (72.3%) of the callers had an underlying mental condition, 68.1% had suicidal ideation while 12.8% had previously attempted suicide. All the crisis callers were offered interventions ranging from phone counselling to linkage to the nearest mental health services. Conclusion: A majority of the crisis callers were offered mental health services, raising the possibility that the availability of telephone helplines may play a role in suicide prevention in Nigeria.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-01-87
      Issue No: Vol. 6, No. 3 (2020)
       
  • Antibacterial activity of crude extracts of the leaves of Nauclea
           latifolia Smith (Rubiaceae) and some selected conventional antibiotics on
           clinical isolates of Salmonella typhi

    • Authors: OL Okunye, PA Idowu, TT Kolade
      Pages: 258 - 264
      Abstract: Background: Nauclea latifolia Smith (Rubiaceae) is a valuable medicinal plant used in folkloric medicine in the treatment of Typhoid fever. The public health significance of Salmonella typhi, the aetiologic agent in typhoid fever lies in the increasing resistance to antimicrobial agents. Objectives: To determine the antimicrobial potentials of the crude extracts of the leaves of Nauclea latifolia on clinical isolates of Salmonella typhi compared with some conventional antibiotics. Methods: Antibiogram was carried out on 25 biochemically confirmed clinical isolates of Salmonella typhi using disc diffusion method of Kirby Bauer. Nauclea latifolia leaves extracted with ethyl acetate and methanol in a Soxhlet apparatus were screened for secondary metabolites. The minimum inhibitory concentrations (MICs) of the extracts were determined by agar dilution method on the isolates. Results: The antibiogram of Samonella typhi showed the following resistance patterns: Augmentin® (24.0%), amoxicillin (44.0%), chloramphenicol (32.0%), gentamicin (20.0%), cloxacillin (96.0%), ciprofloxacin (8.0%), erythromycin (60.0%), tetracycline (32.0%) and cotrimoxazole (60.0%). The extracts showed good antibacterial activity on the clinical isolates including those resistant to antibiotics. The MIC of methanol extract ranged from
      1.56mg/ml to 6.25mg/ml and 3.13mg/ml to 25.0 mg/ml for ethyl acetate extract with exception of isolates 11, 12, 19 and 20 with high MIC values as 50mg/ml.  The methanol and ethyl acetate extracts gave a yield of 11.7% and 3.5% respectively. Bioactive secondary metabolites were detected from the extracts. Conclusion: The crude extracts of the leaves of Nauclea latifolia contained antimicrobial agents that were active on Salmonella typhi which could be used alone and in supportive with conventional antibiotics for therapeutic management of typhoid fever.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-02-88
      Issue No: Vol. 6, No. 3 (2020)
       
  • Prevalence and determinants of current contraceptive use among married
           women in Jada Local Government Area, Adamawa State, Nigeria

    • Authors: S Atinge, M Balogun, E Umahi, C Ejim
      Pages: 265 - 275
      Abstract: Background: Family planning is a cost-effective intervention in the prevention of maternal, infant and child mortality. However, its uptake has been hamstrung by a myriad of factors in Northern Nigeria and sub-Saharan Africa as a whole. Objective: To determine the prevalence as well as determinants of current contraceptive use in Adamawa State, northern Nigeria. Methods: The study was a descriptive cross-sectional in design. The participants were married women of reproductive age in Jada Local Government Area of Adamawa State. Participants were selected by multistage sampling technique. An interviewer-administered structured questionnaire was used for data collection. Results: Five hundred and eighty married women participated in the study. The mean age of the respondents was 30.9±6.6 years. Five hundred and eleven (88.4%) were aware of contraceptives. However, the current rate of contraceptive use was 31.4%. The predictors of contraceptive use included the level of education (p = 0.006) and discussion with husband (p<0.001). The commonest reason cited for non-use of contraceptives was the fear of side effects among 144 (41.6%) women. Conclusion: The prevalence of contraceptive use among married women was higher than the national average. High educational status and discussion of family planning with husband were the predictors of contraceptive use.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-03-89
      Issue No: Vol. 6, No. 3 (2020)
       
  • Haematological parameters of apparently healthy neonates at the Federal
           Medical Centre Bida, North Central Nigeria

    • Authors: OE Ojewole, U Abubakar, AO Olowu
      Pages: 276 - 286
      Abstract: Background: Haematological parameters are used as screening tools for patient’s care and treatment. Objective: To determine the haematological parameters of apparently healthy term Nigerian babies and generate normative data. Methods: This was a descriptive, longitudinal study of consecutively recruited babies. The haematological parameters were determined using venous blood samples drawn at delivery and on the 14th day of life using a haematology auto-analyser. Results: Of the 309 babies recruited on the first day of life, 160 (51.8%) were males while 149 (48.2%) were females. Two hundred and seventy-nine (90.3%) were delivered vaginally.  Most (75%) of the neonates were of Nupe origin. The mean haematocrit, haemoglobin concentration, Mean Corpuscular Volume (MCV), Mean Corpuscular Haemoglobin (MCH), Mean Corpuscular Haemoglobin Concentration (MCHC), Red Blood Cell and reticulocyte count on Day 1 were 48.8±8.0%, 15.0±2.6g/dl, 104.1±8.8fl, 31.9±3.3pg, 30.7±1.7g/dl, 4.7±0.9 (×109/l) and 2.0±1.4% respectively. Corresponding Day 14 values were 41.2±5.2%, 12.8±1.9g/dl, 97.2±9.8fl, 30.3±3.8pg, 31.1±1.7g/dl, 4.5±0.6 (×109/l) and 1.0±0.7% respectively. The mean White Blood Cell (WBC) and platelet counts were 13.3±4.8 (×109/l) and 228.3±81.2 (×109/l) respectively, on the 1st day of life and 10.1±2.4 (×109/l) and 370.1±120.7 (×109/l) respectively on the 14th day. The mean differential WBC counts were 49.4±12.0% for neutrophils and 37.4±11.3% for lymphocytes on the 1st day and 32.4±10.0% and 52.8±9.3% respectively on the 14th day. Conclusion: Neonates from Bida have haematological parameters comparable with previously reported values from other parts of Nigeria.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-04-90
      Issue No: Vol. 6, No. 3 (2020)
       
  • Factors associated with Missed Opportunities for Vaccination among
           

    • Authors: OA Kehinde, YA Kuyinu, OO Odusanya
      Pages: 287 - 297
      Abstract: Background: Low vaccination rates in children remain a major problem in resource-poor areas of the world. Missed opportunities for vaccination may be one of the important contributors to the menace. Objectives: To determine the prevalence of missed opportunities for vaccination and identify factors associated with this among Nigerian children in the first year of life. Methods: The study was a descriptive, cross-sectional study of children who were recruited consecutively and data were obtained using a questionnaire. Results: Two hundred and fifty-six children were recruited. The prevalence of missed opportunities for vaccination was 11.3%. Gender (p = 0.04) and parental socioeconomic status (p = 0.008) were significantly associated with missed opportunities for vaccination. Non- availability of required vaccines and reluctance to open a multi-dose vial of vaccine caused MOV in 55.5% and 51.8% of children respectively. The evaluation of vaccination status among subjects who were not fully vaccinated by health workers was low at 18.3%. Conclusion: The rate of missed opportunities for vaccination was low. Educating caregivers and encouraging health workers to evaluate the vaccination status of children at every contact with a health facility may reduce the prevalence of missed opportunities for vaccination.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-05-91
      Issue No: Vol. 6, No. 3 (2020)
       
  • Bacterial flora of the genital tract in pregnancy and early labour

    • Authors: AO Sule-Odu, AA Akadiri, AA Oluwole, OA Osinupebi, BA Andu, AK Akiseku, AI Lawal, KS Oritogun
      Pages: 298 - 305
      Abstract: Background: Bacterial infections of the reproductive tract are common during pregnancy and have been associated with some pregnancy-related morbidities. There is limited information on the prevalence of bacterial infection of the reproductive tract during labour. Objective: To compare the prevalence of bacterial colonisation of the reproductive tract of pregnant women in early third trimester and early labour, and determine the associated foetal outcome. Methods: High vaginal swabs were collected from 201 pregnant women with gestational age from 26 to 32 weeks at the antenatal clinic of a Nigerian teaching hospital. The samples were processed to isolate bacterial organisms. Repeat samples were collected in early labour. The foetal outcome was assessed and recorded. Results: The prevalence of bacterial colonisation was 31.3% in early third trimester and 21.9% in early labour (p = 0.032). Staphylococcus aureus was the most prevalent organism isolated. Cefoxitin and imipenem were the most sensitive antibiotics. Women who had positive bacterial cultures in pregnancy had a slightly higher risk of low birth weight babies (RR 1.9, CI 0.9-3.7) and neonatal hospitalization (RR 1.8, CI 0.9-3.4) but without statistical significance (p = 0.05, and p = 0.06 respectively). Conclusion: The prevalence of bacterial colonisation of the reproductive tract of pregnant women was significantly higher in early third trimester than in early labour. There was no significant difference in pregnancy outcome between women who had positive bacterial cultures and those with negative cultures.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-06-92
      Issue No: Vol. 6, No. 3 (2020)
       
  • Characteristics of HIV/ Malaria co-infected mothers who did not access
           early infant diagnosis for their HIV-exposed infants in Benin-City,
           Nigeria

    • Authors: AE Sadoh, FE Eki-Udoko
      Pages: 306 - 314
      Abstract: Background: Perinatally-acquired HIV infections rapidly lead to death within one to two years of life. Early infant diagnosis (EID) is the key to early identification with the prompt commencement of treatment. This has been shown to reduce morbidity and mortality. In Nigeria, only 21% of HIV-infected infants are on ARTs. Objective: To determine the characteristics of HIV/Malaria co-infected mothers who did not access EID for their HIV- exposed infants. Methods: HIV infected mothers were recruited from three hospitals during the last trimester of pregnancy and were tested for peripheral and placental malaria at delivery. Socio-demographic and some clinical characteristics were obtained using a proforma. Following delivery, the babies were commenced on the Prevention of Mother to Child Transmission (PMTCT) protocol for HIV including prophylactic Nevirapine therapy, infant feeding counselling and performance of DNA PCR at 6-8 weeks of life. Mothers whose infants did not have DNA PCR results were categorized as having not accessed EID services. Results: Of the 162 infants, only 101 (62.4%) had a DNA PCR test done. The mean age of mothers who did not access EID (31.84±4.8 years) was significantly higher than for mothers who accessed EID (30.58±3.09 years) (p<0.0001). Mothers with low levels of education (p = 0.006), cohabiting mothers (p = 0.0067) and HIV serodiscordant couples (p = 0.0029) were more likely not to access EID. Conclusion: Education, marital status and HIV serodiscordance are significant determinants of accessing EID services. Assessment of these factors at first contact with a pregnant HIV-infected woman allows risk categorisation for default from EID.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-07-93
      Issue No: Vol. 6, No. 3 (2020)
       
  • Relationship between bone markers and cardiovascular risk factors in
           healthy Nigerian adults

    • Authors: AO Ale, OB Familoni, OO Ogunsemi, TO Afe, OO Adeleye, OL Adeyemo
      Pages: 315 - 324
      Abstract: Background: Osteoporosis and cardiovascular diseases are global public health concerns. Both diseases have been linked through common risk factors and biological mechanisms. Objective: To evaluate the association between bone turnover markers (BTM) and some cardiovascular risk factors among healthy Nigerian adults. Methods: This was a cross-sectional, observational study of 80 healthy participants of less than 50 years of age. Clinical data were obtained through an interviewer-based questionnaire. Fasting blood samples were analysed for Osteocalcin (OC), Total Alkaline phosphatase (ALP), 25-hydroxyvitamin D (25-OHVitD), Calcium (Ca), Fasting Blood Glucose (FBG). Two-hour postprandial blood glucose (2HPP) Calcium-phosphorus product calculated (CAP) and 24-hour urinary calcium excretion (CaE) were determined. Results: The mean age of the participants was 32.1±5.8 years, mean BMI was 26.3±4.0kg/m2 and the mean waist circumference (WC) was 79.6±16.0cm. OC was directly correlated with ALP (r = 0.4, p = 0.006) but not with CaE (p = 0.8). Serum OC was inversely correlated with age, BMI and WC. ALP was negatively correlated with FBG (r = - 0.3, p = 0.04), 2HPP (r = - 0.65, p = 0.000). Multivariate regression showed that BTMs-OC, ALP and CAE independently predicted BMI, 2HPP, DBP and FBG respectively. Conclusion: This study showed a relationship between bone markers and selected cardiovascular risk factors in Nigerian adults. Therefore, patients with cardiovascular disease may benefit from bone health screening or vice versa.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-08-94
      Issue No: Vol. 6, No. 3 (2020)
       
  • The attitude of Nigerian women to termination of pregnancies with major
           congenital anomalies

    • Authors: EJ Enabudoso, JA Akinmoladun
      Pages: 325 - 332
      Abstract: Background: When couples are confronted with a pregnancy in which there is a major foetal anomaly, they have only two options: termination of the pregnancy or allowing the baby to be born. Objective: To determine the attitude of pregnant women in Nigeria to termination of pregnancies with major congenital anomalies. Methods: This is a descriptive study undertaken at two centres in Nigeria. Structured and pretested self-administered questionnaire was used for data collection including socio-demographics and attitude to termination of pregnancies with major congenital anomalies.  Results: Three hundred and fifty-six pregnant women participated in the study. Most of the respondents were in the 21-40 years age group. More than half of the participants (236; 66.3%) agreed with the termination of pregnancies with major congenital anomalies and some of their reasons were "to prevent the baby from suffering" and "to prevent waste of resources”. For the 120 (33.7%) who did not agree with termination of such pregnancies, some of their reasons were “to trust God for a miracle” and “hoping that God will not allow such” Conclusion: The findings from this study show that majority of the women were favourably disposed to the termination of pregnancies with major anomalies. However, women with such pregnancies need to be adequately counselled to be aware of the consequences of the decisions they make. Also, in a country where there are legal restrictions of abortion, efforts should be made to consider termination of pregnancies with major anomalies in the abortion laws.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-09-95
      Issue No: Vol. 6, No. 3 (2020)
       
  • Herpes zoster ophthalmicus at a tertiary health facility, South-western
           Nigeria: Clinical presentations and outcome

    • Authors: O Fasina, SJ Hughes
      Pages: 333 - 337
      Abstract: Herpes zoster ophthalmicus is a neurocutaneous disease caused by the human alpha herpes virus Type 3 and it is characterized by reactivation of dormant varicella-zoster virus lying within the trigeminal ganglia. The objective of this study was to describe the clinical presentation and management outcome of patients with herpes zoster ophthalmicus in a tertiary health facility. This was a retrospective study of patients with herpes zoster ophthalmicus managed at the Eye Clinic of a tertiary health facility in the South-western part of Nigeria over eight years. There were 17 patients, comprising five males and the mean age at presentation was 54.9±13.7 years. Seven (41.2%) patients were seropositive for the Human Immunodeficiency Virus (HIV) while nine (52.9%) patients had corneal involvement. Fifteen (88.2%) patients had involvement of the first branch of the trigeminal nerve (V1), and one (5.9%) patient each had involvement of the second branch of the trigeminal nerve (V2) and the first two branches of the trigeminal nerve (V1 and V2). All the patients were managed with oral and topical antiviral medications. Ten patients (58.8%) developed postherpetic neuralgia. In conclusion, Herpes zoster ophthalmicus is strongly associated with HIV seropositivity and older age and a significant proportion of patients develop post-herpetic neuralgia necessitating long term management.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-10-96
      Issue No: Vol. 6, No. 3 (2020)
       
  • Diazoxide use for neonatal hyperinsulinaemic hypoglycaemia in a
           low-resource setting: A Case Report

    • Authors: AO Adekoya, TE Adekanye, OO Abolurin, OO Adebawojo, FG Ajayi, ED Ajibola
      Pages: 338 - 343
      Abstract: The management of neonatal hyperinsulinaemic hypoglycaemia remains a major challenge in hospitalized newborns globally. Diazoxide is one of the recommended therapeutic options. We report a late preterm, male infant of a diabetic mother who suffered severe perinatal asphyxia and had persistent hypoglycaemia requiring progressively increasing intravenous glucose concentrations to as high as 12.5 mg/kg/minute along with intravenous hydrocortisone administration. A critical sample revealed inappropriately high serum insulin, inappropriately low serum cortisol and growth hormone responses. Urinalysis was negative for ketones. With the persistence of hypoglycaemia, oral diazoxide at 5 mg/kg/day with oral hydrochlorothiazide was administered. The infant was diazoxide-responsive with complete resolution of hypoglycaemia. Diazoxide therapy was discontinued after 14 days and he was discharged after one month of admission. This report emphasizes the importance of diazoxide in the management of neonatal transient hyperinsulinaemic hypoglycaemia. The availability and cost of diazoxide, as well as the endocrine and metabolic tests, are major concerns in resource-poor settings.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-11-97
      Issue No: Vol. 6, No. 3 (2020)
       
  • Paediatric perineal injury following explosive blast: A Case Report

    • Authors: NJ Nwashilli, AI Arekhandia
      Pages: 344 - 350
      Abstract: Perineal injury in children is uncommon. Injuries range from minor perineal skin laceration to severe injury to the genitourinary tract, anorectal region and the pelvic bone. The mechanisms of injury are usually attributed to blunt trauma, penetrating injuries like impalement injury, or sexual abuse. Perineal injury resulting from explosive blast in children is rare. The management depends on the time and mode of presentation and examination findings. Early presentation (a few hours after injury) with 1st or 2nd-degree perineal injury may benefit from debridement with primary repair of soft tissues and/or sphincters. Late presentation (days after injury) with 3rd or 4th-degree injury will require diverting colostomy or urinary diversion and wound drainage. This is a report of an unusual case of severe perineal injury in a child following explosive blast sustained while squatting close to packed explosives that got detonated. The perineal injury was initially managed with colostomy and wound drainage. The colostomy was closed after the wound had healed with good faecal continence achieved and without perineal soft tissue or anal sphincteric repair. It is concluded that severe isolated paediatric explosive blast perineal injury is rare but is amenable to surgical care.
      PubDate: 2020-08-22
      DOI: 10.30442/ahr.0603-12-98
      Issue No: Vol. 6, No. 3 (2020)
       
 
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