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  Subjects -> MEDICAL SCIENCES (Total: 8250 journals)
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MEDICAL SCIENCES (2224 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 1)
3D Printing in Medicine     Open Access   (Followers: 4)
4 open     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 6)
ABCS Health Sciences     Open Access   (Followers: 7)
Abia State University Medical Students' Association Journal     Full-text available via subscription   (Followers: 2)
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 46)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access  
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Científica Estudiantil     Open Access  
Acta Facultatis Medicae Naissensis     Open Access  
Acta Herediana     Open Access  
Acta Informatica Medica     Open Access  
Acta Medica (Hradec Králové)     Open Access  
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta Medica International     Open Access  
Acta medica Lituanica     Open Access  
Acta Medica Marisiensis     Open Access  
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access   (Followers: 1)
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 2)
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 6)
Acupuncture and Natural Medicine     Open Access  
Addiction Science & Clinical Practice     Open Access   (Followers: 8)
Addictive Behaviors Reports     Open Access   (Followers: 9)
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / Health Sciences Journal of Adıyaman University     Open Access   (Followers: 1)
Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi     Open Access  
Advanced Biomedical Research     Open Access  
Advanced Health Care Technologies     Open Access   (Followers: 8)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 8)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 7)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 26)
Advances in Life Course Research     Hybrid Journal   (Followers: 9)
Advances in Lipobiology     Full-text available via subscription   (Followers: 1)
Advances in Medical Education and Practice     Open Access   (Followers: 32)
Advances in Medical Ethics     Open Access   (Followers: 1)
Advances in Medical Research     Open Access   (Followers: 1)
Advances in Medical Sciences     Hybrid Journal   (Followers: 8)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Medicine     Open Access   (Followers: 3)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 5)
Advances in Molecular Oncology     Open Access   (Followers: 2)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7)
Advances in Parkinson's Disease     Open Access  
Advances in Phytomedicine     Full-text available via subscription  
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
Advances in Regenerative Medicine     Open Access   (Followers: 3)
Advances in Skeletal Muscle Function Assessment     Open Access  
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 15)
Advances in Virus Research     Full-text available via subscription   (Followers: 6)
Advances in Wound Care     Hybrid Journal   (Followers: 12)
Aerospace Medicine and Human Performance     Full-text available via subscription   (Followers: 13)
African Health Sciences     Open Access   (Followers: 3)
African Journal of Biomedical Research     Open Access   (Followers: 1)
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 2)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 3)
African Journal of Thoracic and Critical Care Medicine     Open Access  
African Journal of Trauma     Open Access   (Followers: 1)
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 9)
AJOB Primary Research     Partially Free   (Followers: 3)
AJSP: Reviews & Reports     Hybrid Journal  
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access   (Followers: 2)
ALERTA : Revista Científica del Instituto Nacional de Salud     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 4)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 2)
Althea Medical Journal     Open Access   (Followers: 2)
American Journal of Biomedical Engineering     Open Access   (Followers: 15)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 7)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 4)
American Journal of Clinical Medicine Research     Open Access   (Followers: 8)
American Journal of Family Therapy     Hybrid Journal   (Followers: 10)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 11)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 5)
American Journal of Managed Care     Full-text available via subscription   (Followers: 12)
American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 4)
American Journal of Medicine     Hybrid Journal   (Followers: 50)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access   (Followers: 2)
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 10)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 5)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 5)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 6)
Anatolian Clinic the Journal of Medical Sciences     Open Access  
Anatomica Medical Journal     Open Access  
Anatomical Science International     Hybrid Journal   (Followers: 3)
Anatomical Sciences Education     Hybrid Journal   (Followers: 1)
Anatomy     Open Access   (Followers: 2)
Anatomy Research International     Open Access   (Followers: 3)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Ankara Medical Journal     Open Access   (Followers: 2)
Ankara Üniversitesi Tıp Fakültesi Mecmuası     Open Access  
Annales de Pathologie     Full-text available via subscription  
Annales des Sciences de la Santé     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 2)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 3)
Annals of Bioanthropology     Open Access   (Followers: 5)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 19)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 4)
Annals of Clinical Hypertension     Open Access  
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 12)
Annals of Family Medicine     Open Access   (Followers: 14)
Annals of Health Research     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 7)
Annals of Microbiology     Hybrid Journal   (Followers: 11)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Rehabilitation Medicine     Open Access  
Annals of Saudi Medicine     Open Access  
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 5)
Annual Review of Medicine     Full-text available via subscription   (Followers: 17)
Anthropological Review     Open Access   (Followers: 24)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Technology Journal     Open Access   (Followers: 1)
Antibody Therapeutics     Open Access  
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 1)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 4)
Applied Clinical Research, Clinical Trials and Regulatory Affairs     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 13)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access   (Followers: 1)
Archives Medical Review Journal / Arşiv Kaynak Tarama Dergisi     Open Access  
Archives of Asthma, Allergy and Immunology     Open Access  
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 4)
Archives of Medicine and Surgery     Open Access  
Archives of Trauma Research     Open Access   (Followers: 3)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access   (Followers: 1)
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
Ars Medica : Revista de Ciencias Médicas     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Full-text available via subscription   (Followers: 17)
Arterial Hypertension     Open Access   (Followers: 1)
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 17)
Artificial Organs     Hybrid Journal   (Followers: 1)
ASHA Leader     Open Access  
Asia Pacific Family Medicine     Open Access   (Followers: 1)
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 12)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 3)
Asian Biomedicine     Open Access   (Followers: 2)
Asian Journal of Cell Biology     Open Access   (Followers: 5)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 4)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 2)
Asian Journal of Medical Sciences     Open Access   (Followers: 2)
Asian Journal of Scientific Research     Open Access   (Followers: 3)
Asian Journal of Transfusion Science     Open Access   (Followers: 1)
Asian Medicine     Hybrid Journal   (Followers: 5)
Asian Pacific Journal of Cancer Prevention     Open Access  
ASPIRATOR : Journal of Vector-borne Disease Studies     Open Access  
Astrocyte     Open Access  
Atención Familiar     Open Access  
Atención Primaria     Open Access   (Followers: 1)
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche     Open Access  
Audiology - Communication Research     Open Access   (Followers: 10)
Auris Nasus Larynx     Full-text available via subscription  
Australian Coeliac     Full-text available via subscription   (Followers: 1)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Journal of Medical Science     Full-text available via subscription   (Followers: 1)

        1 2 3 4 5 6 7 8 | Last

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Journal Cover
Atti della Accademia Peloritana dei Pericolanti - Classe di Scienze Medico-Biologiche
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Online) 1828-6550
Published by Accademia Peloritana dei Pericolanti Homepage  [1 journal]
  • Endoscopic thyroidectomy: why we need a transoral approach

    • Authors: Antonina Catalfamo, Fausto Famà, Francesca Pia Pergolizzi, Maribel Cristina Sanchez Cruz, Giorgio De Pasquale, Sam Mahli, Gianlorenzo Dionigi
      First page: 1
      Abstract: Transoral thyroidectomy (TT) is a feasible novel surgical procedure that does not need visible incisions, a truly scar-free surgery. Inclusion criteria are (a) patients who have a ultrasonographically (US) estimated thyroid diameter not larger than 10 cm, (b) US estimated gland volume ≤45 mL, (c) nodule size ≤50 mm, (d) a benign tumor, such as a thyroid cyst, single-nodular goiter, or multinodular goiter, (e) follicular neoplasm, (f) papillary microcarcinoma without evidence of metastasis. The procedure is carried out through three-port technique placed at the  oral vestibule, one 10-mm port for 30° endoscope and two additional 5-mm ports for dissecting and coagulating instruments. CO2insufflation pressure is set at 6 mmHg. An anterior cervical subplatysmal space is created from the oral vestibule down to the sternal notch, laterally to the sterncleidomuscles. TT is done fully endoscopically using conventional endoscopic instruments. TT represents probably the best scarless approach to the thyroid due to the short distance between the thyroid and the incisions, respecting the surgical planes.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • Atypical Presentation of Chronic Granulomatous Disease in a Child

    • Authors: Chiara Cuzzupè, Simona Santucci, Elda Pitrolo, Celeste Casto, Irene Viola, Claudio Romano, Mariella Valenzise, Filippo De Luca
      First page: 1
      Abstract: Chronic granulomatous disease is a rare, inherited immunodeficiency caused by deletions or mutations in genes that encode subunits of the NADPH oxidase complex. The pattern of chronic granulomatous disease inheritance can be X-linked (about 70% of cases) or autosomal recessive. The basic defect lies in phagocytic cells (neutrophils and monocytes) which fail to effectively destroy invading bacteria and fungi. Also, a dysregulated immune response, characterized by extensive granulomatous inflammation of visceral organs, develops in patients. This immunodeficiency is characterized by repeated suppurative infections mainly located in the lungs, skin, and lymph nodes, but also affecting other organs. The major agents involved in the infections are catalase positive bacteria, mycobacteria, fungi, and other opportunistic germs. Diagnosis is based on clinical suspicion and confirmed by nitroblue tetrazolium test or flow cytometry that demonstrate the inability of phagocytes from affected individuals to produce superoxides. The treatment of chronic granulomatous disease involves, in addition to general care such as the prevention of infections and vaccinations, the use of sulfamethoxazole–trimethoprim in combination with itraconazole for prophylaxis. We report the case of a 3-year-old boy with medical history of recurrent respiratory infections, anemia, growth failure, elevated inflammatory markers and occasional rectal bleeding. He was admitted to our department for a suspected chronic bowel inflammatory disease. Clinical history, lymph nodes involvement and the discovery of intestinal granulomas on biopsies confirmed the diagnosis of chronic granulomatous disease.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • Psychological factors may impacton postmenopausal women fracture risk

    • Authors: Federica Bellone, Antonino Catalano, Gabriella Martino, Carmen Lasco, Annamaria Pugliese, Nunziata Morabito
      First page: 1
      Abstract: Anxiety and osteoporosis are common diseases and major public health problems. The association between  anxiety levels and bone loss was poorly investigated, thus we aimed to explore whether anxiety severity could be considered as an independent fracture risk. In a setting of postmenopausal women we measured anxiety levels by Hamilton Anxiety Rating Scale (HAMA), depressive symptoms by Beck Depression Inventory and evaluated quality of life by the 36-Item Short Form Health Survey (SF-36) questionnaire. Women with higher anxiety levels showed lower BMD at lumbar spine and femoral neck, and exhibited a poorer quality of life after grouping our population in tertiles of HAMA score. Anxiety levels were predictive of reduced BMD after correcting for other known clinical risk of fractures.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • What do we know about occult hepatitis B virus infection'

    • Authors: Francesca Saffioti, Giovanni Raimondo
      First page: 2
      Abstract: Occult hepatitis B virus (HBV) infection (OBI) is recognized as one of the phases in the natural history of chronic HBV infection and defines the persistence of HBV genomes in the hepatocytes of individuals testing negative for HBV surface antigen (HBsAg) and detectable or undetectable HBV DNA in the serum. Occasionally, OBI is related to the infection with mutant viruses producing a modified HBsAg undetectable by diagnostic kits or with replication-defective variants. However, in most cases OBI is due to replication-competent viruses that are strongly suppressed in their activities by the host’s defence mechanisms. Growing evidence indicates that genetic, epigenetic and post-transcriptional mechanisms may be involved in the control of HBV activities and in the OBI occurrence.  OBI may be involved in several different clinical contexts, which can be grouped in four main categories: 1) transmission of the “occult” virus (mainly, through blood transfusion and orthotopic liver transplantation from OBI donors) causing classic forms of hepatitis B in the HBV naïve recipients; 2) reactivation of the HBV infection following the development of an immunosuppressive status, resulting in acute and occasionally fulminant hepatitis; 3) contribution to the progression of patients with various causes of liver disease toward cirrhosis; 4) involvement in hepatocarcinogenesis, likely through the maintenance of the direct and indirect pro-oncogenic properties typical of the overt HBV infection (such as the capacity to integrate in the host’s genome and to synthesize pro-oncogenic proteins) and by provoking a mild but persisting necroinflammation which favours cirrhosis development.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • Thyroid dysfunction in patients treated with the immune checkpoint
           inhibitor nivolumab: different clinical features

    • Authors: Giuseppe Giuffrida, Alfredo Campennì, Francesco Trimarchi, Rosaria M. Ruggeri
      First page: 2
      Abstract: Rationale. Immune Checkpoint Inhibitors (ICIs) are approved for some advanced neoplasms, increasing survival. ICIs block inhibitor receptors cytotoxic T lymphocyte antigen 4 (CTLA4) and programmed death-1 (PD-1) and trigger T cell-mediated immunity against tumor. Their action is accompanied by several immunity-related adverse events (IRAEs), also involving the endocrine system (pituitary, thyroid, adrenals). We report two different cases of thyrotoxicosis following administration of the anti-PD-1 nivolumab. Patients. Patient 1, M, 75 years-old, treated for non-small cell lung carcinoma (NSCLC) since September 2016, with euthyroid multinodular goiter. In January 2017 (12 weeks from baseline), he developed frank hyperthyroidism, with positive TSH-receptor antibodies (TRAb) and thyroperoxidase antibodies (TPOAb). A Tc99m thyroid scintiscan showed diffuse uptake and “cold” areas. After nivolumab withdrawal, treatment with metimazole (MMI) 5 mg per day was started and euthyroidism was resumed, so to restart the drug in May 2017. Patient 2, M, 80 years-old, treated for a left-eye choroid melanoma since January 2017, with euthyroid nodular goiter. In April 2017 (6 weeks from baseline), thyrotoxicosis was detected, with positive thyroglobulin antibodies (Tg-Ab, 244 IU/ml, nv <4) and no scintiscan uptake, as in destructive thyroiditis. Scalar-dose prednisone was initiated, and after 3 months TSH was >4.5 µIU/ml (subclinical hypothyroidism). Patient was treated with replacement doses of levothyroxine (LT-4), and continued nivolumab infusions. Conclusions. Two forms of thyrotoxicosis were reported: the first with thyroid hyperfunction and positive TRAb, the latter as a destructive thyroiditis. In both cases (mean onset after 9 weeks), the moderate severity and the appropriate management of endocrine IRAEs allowed treatment continuation.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • The influence of cognitive factors on pathological gambling

    • Authors: Tindara Caprì, Angela Foti, Rosa Angela Fabio, Annamaria Pugliese, Gabriella Martino
      First page: 2
      Abstract: The purpose of this study wasto examine the role of cognitive factors, such as superstition, locus of control, decision-making and unrealistic optimism,on gambling.Eighty-six subjects participated in this study. They were divided into four groups: non-players, social players, problem gamblers, and pathological gamblers. Groups were formed on the basis of South Oaks Gambling Screen  Scale. Results showed that pathological gamblers group obtained a high superstition index. With reference to unrealistic optimism, gambler groupbelieved that they had a better chance of success compared to non-gamblers. They also showed a higher impulsivity index in decision making than non-gamblers. This study supports the idea that cognitive factors such as superstition, unrealistic optimism, impulsivity and external locus of control are involved in gambling.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • Chronic paroxysmal hemicrania in an adult responding to valproate: a case
           report

    • Authors: Daniela Parisi, Giuseppe Vita, Massimo Autunno
      First page: 3
      Abstract: Chronic paroxysmal hemicrania (CPH) is a rare primary headache syndrome classified as a trigeminal autonomic cephalalgia. It is characterized by repeated attacks of severe, strictly unilateral and short-lasting pain occurring with cranial autonomic features. The absolute response to indomethacin represents the diagnostic key. Unfortunately, often, treatment with indomethacin may cause adverse events, mostly gastrointestinal. We report the case of a 53-year-old male affected by CPH responding to indomethacin, which had to be withdrawn because of gastric side effects. He had a subsequent good and prolonged response to valproate. Our observation suggests the potential use of valproate as a treatment option in patients with CPH with contraindications or intolerance to indomethacin.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • In GH-treated girls with Turner syndrome height prognosis may sometimes
           exceed target height: a case report

    • Authors: Giorgia Pepe, Tommaso Aversa, Rosy Civa, Domenico Corica, Letteria Morabito, Filippo De Luca, Malgorzata Wasniewska
      First page: 4
      Abstract: A 5-years-old girl was diagnosed with Turner syndrome (TS) during a diagnostic work-up for short stature and dysmorphic features. Chromosome analysis revealed rare X-chromosomal abnormalities 46 Xt (13:X) (p12:q24). GH therapy was started at the age of 5.5 years, and continued for 7 years with a fixed dose of 0.33 mg/kg/week, until adult height (AH) achievement. Six-monthly assessment of height standard deviation score and height velocity was performed under therapy, evaluating a prepubertal height gain of 31.7 cm and pubertal height gain of 20 cm. She achieved an AH of 159.3 cm, better than her target height (156.8 cm). In addition, she underwent spontaneous puberty at the age of 9.6 years, completed with menarche at 11.6 years and followed by regular menstrual cycles.  During GH treatment, IGF-1, insulin and glucose blood levels remained within a normal range. The early onset of GH therapy may have allowed such a successful height outcome, with the achievement of full stature recovery during childhood and puberty in this TS case. The rare karyotype of our patient may also positively influenced her height final result.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • An unusual evolution of pneumonia in a child

    • Authors: Simona Santucci, Chiara Cuzzupè, Elda Pitrolo, Francesco Monaco, Carmelo Romeo, Concetta Sferlazzas, Mariella Valenzise, Filippo De Luca
      First page: 5
      Abstract: Pleural empyema represents a severe complication of community acquired pneumonia with an incidence of 0.6% among hospitalized children.  Clinical manifestations of picture may be different in infants and young children and it should always be suspected in a child with pneumonia without significant clinical improvement after 48 hours of antibiotic treatment.  The most common microorganism associated with empyema is Streptococcus pneumoniae, especially in children under 5 years of age. Chest radiograph is the gold standard for diagnosis but chest ultrasonography,  and in some cases chestCT,  may be necessary to study features and evolution of the pleural fluid in order to guide therapeutic choices.  In most cases small pleural empyema responds to antibiotics alone. However in severe and extensive cases, drainage and invasive treatments, like video-assisted thoracic surgery (VATS) and thoracotomy, became necessary.  Due to the early start of antibiotic therapy, blood and pleural fluid cultures may result negative; in these cases only the use of molecular techniques, like polymerase chain reaction in biological fluids, may determine the etiology of the infection.  Here we report the case of previously healthy 8-years-old boy with an important and severe pleural empyema as a complication of S. Pneumoniae pneumonia, that did not respond to antibiotic therapy and thoracocentesis and for which decortication has been necessary. In our patient only molecular analysis on pleuric fluid has allowed us to define the etiology of the process.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • A case of amiodarone-induced hypothyroidism in a mild to moderate iodine
           deficiency area

    • Authors: Roberto Vita, Salvatore Benvenga
      First page: 6
      Abstract: Thyroid dysfunction associated to amiodarone treatment depends on iodine intake, as thyrotoxicosis occurs more frequently in iodine deficiency areas, whereas hypothyroidism in iodine sufficient areas. We present here a case of severe overt hypothyroidism induced by prolonged treatment with amiodarone for atrial fibrillation in a man living in a low iodine intake area. The case was managed with levothyroxine (LT4) replacement and amiodarone withdrawal. Euthyroidism was restored after two months, and atrial fibrillation has not relapsed to date.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • Corneal dystrophy in a cocker spaniel dog: a case report

    • Authors: Monica Ragusa, Michela Pugliese, Domenico Britti, Ernesto Palma, Antonio Pugliese
      First page: 7
      Abstract: A 1-year-old female Cocker Spaniel dog was examined at the ophthalmology service of the Veterinary Teaching Hospital - University of Messina (Italy) for evaluation of symmetrical white spots in both corneas and “red eyes”. Dog was clinically healthy, haematological and biochemical examination were unremarkable, Leishmania PCR was negative. After a complete ophthalmic examination, the clinical diagnosis was corneal stromal dystrophy with uveitis-induced. In dogs, corneal stromal dystrophy is a primary, inherited, bilateral opacity of the corneanot associated with ocular inflammation or systemic disease. Detailed description of corneal dystrophy are available only for few breeds. This lesion is not progressive and treatment is not usually recommended unless vision is impaired or the deposits become irritating.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
  • Glaucoma and lens subluxation in a crossbred Puli X Pumi dog: a case
           report

    • Authors: Monica Ragusa, Michela Pugliese, Domenico Britti, Ernesto Palma, Antonio Pugliese
      First page: 8
      Abstract: The Pumi is a rare sheep-herding terrier breed dog selected in Hungary from the Puli breed mixed with French and German herding dogs since the 17th century. The current case report described a 9.5 years old, cross-breed Puli/Pumi, male dog with clinical signs of glaucoma and intraocular inflammation accompanied  by lens subluxation and no abnormal gonioscopic findings in the left eye. At the presentation,  the dog appeared painful and blind in the left eye. Diagnose of glaucoma was made at the ophthalmological examination. Furthermore, glaucoma was suspected to be caused by a primary subluxation and vitreous debris. An intensive medical treatment was performed without considerable improve of eye condition, and disruption of ciliary body was finally performed through gentamicin injection. One week after surgery, there was a severe reduction of IOP in the left eye from the preoperative value of 50 mmHg to 9 mmHg. Persistent intraocular inflammation justified postoperative treatment with topical corticoids. So far there are no published reports of inherited ocular conditions in Pumi and in this crossbreed and/or the numbers of individuals for which examinations are recorded are too low to identify the presence of significant ocular disorders. Examinations are encouraged to accumulate information and reduce the likelihood of undetected conditions becoming problematic.
      PubDate: 2017-12-21
      Issue No: Vol. 105, No. 2 (2017)
       
 
 
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