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  Subjects -> MEDICAL SCIENCES (Total: 7797 journals)
    - ALLERGOLOGY AND IMMUNOLOGY (196 journals)
    - ANAESTHESIOLOGY (111 journals)
    - CARDIOVASCULAR DISEASES (323 journals)
    - CHIROPRACTIC, HOMEOPATHY, OSTEOPATHY (21 journals)
    - COMMUNICABLE DISEASES, EPIDEMIOLOGY (210 journals)
    - DENTISTRY (262 journals)
    - DERMATOLOGY AND VENEREOLOGY (157 journals)
    - EMERGENCY AND INTENSIVE CRITICAL CARE (116 journals)
    - ENDOCRINOLOGY (146 journals)
    - FORENSIC SCIENCES (38 journals)
    - GASTROENTEROLOGY AND HEPATOLOGY (173 journals)
    - GERONTOLOGY AND GERIATRICS (128 journals)
    - HEMATOLOGY (145 journals)
    - HYPNOSIS (4 journals)
    - INTERNAL MEDICINE (151 journals)
    - LABORATORY AND EXPERIMENTAL MEDICINE (94 journals)
    - MEDICAL GENETICS (58 journals)
    - MEDICAL SCIENCES (2005 journals)
    - NURSES AND NURSING (316 journals)
    - OBSTETRICS AND GYNECOLOGY (195 journals)
    - ONCOLOGY (359 journals)
    - OPHTHALMOLOGY AND OPTOMETRY (127 journals)
    - ORTHOPEDICS AND TRAUMATOLOGY (159 journals)
    - OTORHINOLARYNGOLOGY (81 journals)
    - PATHOLOGY (100 journals)
    - PEDIATRICS (257 journals)
    - PHYSICAL MEDICINE AND REHABILITATION (149 journals)
    - PSYCHIATRY AND NEUROLOGY (780 journals)
    - RADIOLOGY AND NUCLEAR MEDICINE (187 journals)
    - RESPIRATORY DISEASES (96 journals)
    - RHEUMATOLOGY (66 journals)
    - SPORTS MEDICINE (74 journals)
    - SURGERY (371 journals)
    - UROLOGY, NEPHROLOGY AND ANDROLOGY (142 journals)

MEDICAL SCIENCES (2005 journals)            First | 1 2 3 4 5 6 7 8 | Last

Showing 401 - 600 of 3562 Journals sorted alphabetically
Cogent Medicine     Open Access  
Cold Spring Harbor Perspectives in Medicine     Full-text available via subscription   (Followers: 1)
Colombia Forense     Open Access  
Colombia Médica     Open Access   (Followers: 1)
Colorectal Cancer: Open Access     Open Access  
Coluna/Columna     Open Access  
Combination Products in Therapy     Open Access  
Community Based Medical Journal     Open Access  
Comparative Effectiveness Research     Open Access  
Comparative Medicine     Full-text available via subscription   (Followers: 3)
Complementary Medicine Research     Full-text available via subscription  
Comprehensive Series in Photosciences     Full-text available via subscription  
Comptes Rendus Geoscience     Full-text available via subscription   (Followers: 9)
Computational and Mathematical Methods in Medicine     Open Access   (Followers: 2)
Computers in Biology and Medicine     Hybrid Journal   (Followers: 10)
ConScientiae Saúde     Open Access  
Contemporary Clinical Trials     Hybrid Journal   (Followers: 4)
Contemporary Clinical Trials Communications     Open Access  
Contemporary Drug Problems     Full-text available via subscription   (Followers: 2)
Core Evidence     Open Access  
Correo Científico Médico     Open Access  
Cortex     Hybrid Journal   (Followers: 18)
CRANIO® : The Journal of Craniomandibular & Sleep Practice     Hybrid Journal   (Followers: 2)
Critical Ultrasound Journal     Open Access   (Followers: 3)
Cuadernos de Bioetica     Open Access   (Followers: 1)
Cukurova Medical Journal     Open Access   (Followers: 2)
Cumhuriyet Medical Journal     Open Access  
Curare     Open Access  
Current Aging Science     Hybrid Journal   (Followers: 2)
Current Attention Disorders Reports     Hybrid Journal   (Followers: 1)
Current Biomarker Findings     Open Access   (Followers: 1)
Current Clinical Microbiology Reports     Hybrid Journal   (Followers: 3)
Current Developmental Disorders Reports     Hybrid Journal   (Followers: 3)
Current Directions in Biomedical Engineering     Open Access  
Current GERD Reports     Hybrid Journal  
Current Issues in Pharmacy and Medical Sciences     Open Access   (Followers: 3)
Current Medical Issues     Open Access   (Followers: 1)
Current Medical Research and Opinion     Hybrid Journal   (Followers: 19)
Current Nanomedicine     Hybrid Journal  
Current Opinion in Molecular Therapeutics     Full-text available via subscription   (Followers: 14)
Current Pathobiology Reports     Hybrid Journal  
Current Regenerative Medicine     Hybrid Journal  
Current Research : Concussion     Open Access  
Current Research in Medicine     Open Access   (Followers: 3)
Current Signal Transduction Therapy     Hybrid Journal  
Current Tissue Engineering     Hybrid Journal   (Followers: 3)
Current Topics in Medicinal Chemistry     Hybrid Journal   (Followers: 9)
Current Topics in Microbiology and Immunology     Hybrid Journal   (Followers: 12)
Current Traditional Medicine     Hybrid Journal  
Current Transplantation Reports     Hybrid Journal   (Followers: 1)
Current Trauma Reports     Hybrid Journal   (Followers: 1)
Current Tropical Medicine Reports     Hybrid Journal  
CVD Prevention and Control     Hybrid Journal  
CytoJournal     Open Access   (Followers: 2)
Cytokine     Hybrid Journal   (Followers: 7)
Dados - Revista de Ciências Sociais     Open Access  
Danish Medical Journal     Partially Free   (Followers: 7)
Dar Es Salaam Medical Students' Journal     Open Access  
Das Gesundheitswesen     Hybrid Journal   (Followers: 6)
Decision Sciences Journal of Innovative Education     Hybrid Journal   (Followers: 5)
Delta Medical College Journal     Open Access  
Denkbeeld     Hybrid Journal  
Dentistry and Medical Research     Open Access  
Der Freie Zahnarzt     Hybrid Journal  
Der Gynakologe     Hybrid Journal   (Followers: 3)
Der Klinikarzt     Hybrid Journal  
Der Notarzt     Hybrid Journal   (Followers: 3)
Der Nuklearmediziner     Hybrid Journal  
Deutsche Zeitschrift für Akupunktur     Full-text available via subscription   (Followers: 2)
Developments in Volcanology     Full-text available via subscription   (Followers: 3)
Diabetology International     Hybrid Journal   (Followers: 6)
Diagnostic and Interventional Imaging     Full-text available via subscription  
Diagnostic and Prognostic Research     Open Access  
Diagnostics     Open Access   (Followers: 1)
Diálisis y Trasplante     Full-text available via subscription  
Dialyse aktuell     Hybrid Journal  
Dicle Tıp Dergisi / Dicle Medical Journal     Open Access  
Die Hebamme     Hybrid Journal  
Digital Medicine     Open Access  
Directieve therapie     Hybrid Journal  
Disability, CBR & Inclusive Development     Open Access   (Followers: 14)
Disaster and Military Medicine     Open Access   (Followers: 4)
Disease Markers     Open Access   (Followers: 1)
Disease Models and Mechanisms     Open Access   (Followers: 1)
Diseases     Open Access  
DMW - Deutsche Medizinische Wochenschrift     Hybrid Journal   (Followers: 30)
DoctorConsult - The Journal. Wissen für Klinik und Praxis     Full-text available via subscription  
Doklady Biological Sciences     Hybrid Journal  
Doklady Earth Sciences     Hybrid Journal   (Followers: 2)
Dokuz Eylül Üniversitesi Tıp Fakültesi Dergisi     Open Access  
Douleurs : Evaluation - Diagnostic - Traitement     Full-text available via subscription   (Followers: 1)
Drug and Therapeutics Bulletin     Hybrid Journal   (Followers: 8)
Drug Delivery and Translational Research     Hybrid Journal   (Followers: 2)
Drug Development and Therapeutics     Open Access  
Drug Resistance Updates     Hybrid Journal   (Followers: 3)
Duazary     Open Access   (Followers: 1)
Düzce Tıp Fakültesi Dergisi / Duzce Medical Journal     Open Access  
Düzce Üniversitesi Sağlık Bilimleri Enstitüsü Dergisi / Journal of Duzce University Health Sciences Institute     Open Access  
Dynamis : Acta Hispanica ad Medicinae Scientiarumque Historiam Illustrandam     Open Access   (Followers: 2)
Early Science and Medicine     Hybrid Journal   (Followers: 5)
East African Journal of Public Health     Full-text available via subscription   (Followers: 4)
East African Medical Journal     Full-text available via subscription   (Followers: 2)
Eating and Weight Disorders - Studies on Anorexia, Bulimia and Obesity     Hybrid Journal   (Followers: 20)
EBioMedicine     Open Access  
Ebonyi Medical Journal     Full-text available via subscription  
Educación Matemática     Open Access  
Educación Médica     Open Access   (Followers: 1)
Educación Médica Superior     Open Access   (Followers: 1)
Educational Research in Medical Sciences Journal     Open Access   (Followers: 4)
EDUMECENTRO     Open Access  
Eesti Arst     Open Access  
Ege Tıp Dergisi / Ege Journal of Medicine     Open Access  
Egyptian Journal of Basic and Applied Sciences     Open Access  
Egyptian Journal of Ear, Nose, Throat and Allied Sciences     Open Access   (Followers: 1)
Egyptian Liver Journal     Partially Free   (Followers: 2)
Egyptian Spine Journal     Open Access  
EIDON     Open Access  
Einstein (São Paulo)     Open Access  
EJNMMI Physics     Open Access  
EJNMMI Research     Open Access  
eJurnal Kedokteran Indonesia     Open Access  
EJVES Short Reports     Open Access   (Followers: 1)
El Mednifico Journal     Open Access  
eLife     Open Access   (Followers: 69)
EMC - AKOS - Trattato di Medicina     Hybrid Journal  
EMC - Kinesiterapia - Medicina Física     Full-text available via subscription  
EMC - Podología     Full-text available via subscription  
EMC - Tratado de medicina     Full-text available via subscription  
Endo-Praxis     Hybrid Journal   (Followers: 1)
Enfermeria Actual en Costa Rica     Open Access   (Followers: 2)
Environmental Disease     Open Access   (Followers: 3)
EP-Europace     Hybrid Journal   (Followers: 2)
Epigenetic Diagnosis & Therapy     Hybrid Journal  
Epilepsy Research     Hybrid Journal   (Followers: 7)
Epileptic Disorders     Hybrid Journal   (Followers: 1)
Epileptology     Hybrid Journal  
EPJ Nonlinear Biomedical Physics     Open Access  
ESMO Open     Open Access  
Ethics, Medicine and Public Health     Full-text available via subscription   (Followers: 5)
Ethik in der Medizin     Hybrid Journal  
Eurasian Journal of Health Technology Assessment     Open Access  
European Cytokine Network     Full-text available via subscription   (Followers: 1)
European Journal of Anatomy     Full-text available via subscription   (Followers: 4)
European Journal of Clinical Investigation     Hybrid Journal   (Followers: 7)
European Journal of General Practice     Hybrid Journal   (Followers: 6)
European Journal of Integrative Medicine     Hybrid Journal   (Followers: 3)
European Journal of Medical Research     Open Access   (Followers: 1)
European Journal of Medicinal Chemistry     Hybrid Journal   (Followers: 24)
European Journal of Podiatry / Revista Europea de Podología     Open Access   (Followers: 2)
European Medical, Health and Pharmaceutical Journal     Open Access   (Followers: 1)
European Radiology Experimental     Open Access  
European Research in Telemedicine / La Recherche Européenne en Télémédecine     Full-text available via subscription   (Followers: 2)
European Research Journal     Open Access   (Followers: 2)
European Review for Medical and Pharmacological Sciences     Full-text available via subscription   (Followers: 1)
European Scientific Journal     Open Access   (Followers: 3)
European Surgical Research     Full-text available via subscription   (Followers: 2)
Evidence & Policy : A Journal of Research, Debate and Practice     Full-text available via subscription   (Followers: 12)
Evidence-Based Medicine     Hybrid Journal   (Followers: 34)
Evidence-based Medicine & Public Health     Open Access   (Followers: 7)
Evidence-based Preclinical Medicine     Open Access  
Expert Evidence     Hybrid Journal  
Expert Opinion on Drug Safety     Hybrid Journal   (Followers: 13)
Expert Opinion on Therapeutic Targets     Hybrid Journal   (Followers: 16)
Expert Review of Medical Devices     Hybrid Journal   (Followers: 5)
Expert Reviews in Molecular Medicine     Hybrid Journal   (Followers: 1)
EXPLORE: The Journal of Science and Healing     Hybrid Journal   (Followers: 2)
Extreme Physiology & Medicine     Open Access   (Followers: 1)
F1000Research     Open Access   (Followers: 4)
Facta Universitatis, Series : Medicine and Biology     Open Access  
Family Medicine and Community Health     Open Access   (Followers: 7)
Family Practice     Hybrid Journal   (Followers: 16)
Family Practice & Palliative Care     Open Access   (Followers: 1)
Family Practice Management     Full-text available via subscription   (Followers: 2)
Faridpur Medical College Journal     Open Access  
FEM : Revista de la Fundación Educación Médica     Open Access  
Fibrogenesis & Tissue Repair     Open Access  
Finlay : Revista de Enfermedades no Transmisibles     Open Access  
Fisioterapia     Full-text available via subscription   (Followers: 2)
Fisioterapia & Saúde Funcional     Open Access   (Followers: 2)
Fisioterapia e Pesquisa     Open Access  
Flugmedizin · Tropenmedizin · Reisemedizin - FTR     Hybrid Journal  
FMC - Formación Médica Continuada en Atención Primaria     Full-text available via subscription   (Followers: 1)
Folia Medica     Open Access   (Followers: 1)
Folia Medica Facultatis Medicinae Universitatis Saraeviensis     Open Access  
Folia Medica Indonesiana     Open Access  
Folia Morphologica     Full-text available via subscription  
Folia Phoniatrica et Logopaedica     Full-text available via subscription  
Fontanus     Open Access  
Foodborne Pathogens and Disease     Hybrid Journal   (Followers: 10)
Foot & Ankle Specialist     Hybrid Journal   (Followers: 3)
Foot and Ankle Clinics     Full-text available via subscription   (Followers: 11)
Foot and Ankle Online Journal     Full-text available via subscription   (Followers: 6)
Forum Medycyny Rodzinnej     Hybrid Journal  
Forum Zaburzeń Metabolicznych     Hybrid Journal  
Frontières     Full-text available via subscription   (Followers: 1)
Frontiers in Medicine     Open Access   (Followers: 2)
Frontiers in Neuroprosthetics     Open Access   (Followers: 5)
Frontiers in Synaptic Neuroscience     Open Access  
Frontiers of Medical and Biological Engineering     Hybrid Journal   (Followers: 1)
Frontiers of Medicine     Hybrid Journal   (Followers: 2)

  First | 1 2 3 4 5 6 7 8 | Last

Journal Cover
European Research Journal
Number of Followers: 2  

  This is an Open Access Journal Open Access journal
ISSN (Online) 2149-3189
Published by DergiPark Homepage  [118 journals]
  • MicroRNA-33a levels do not correlate with the expression of its host gene
           SREBF2 and its isoforms in prostate cancer cell lines

    • Authors: Ömer Faruk Karataş; Michael Ittmann
      Abstract: Objectives. Prostate canceris currently the most frequently diagnosed malignantneoplasm and the second leading cause of cancer relatedmortality in men over the age of 50 years in the developed countries. MicroRNA-33a(miR-33a), localized within the intron 16 of SREBF2, has been reported to have tumor suppressive properties insome cancers including prostate cancer, whereas its host gene, SREBF2, has beenshown to be elevated in prostate cancer and to act as an oncogene. Due to theparadoxical expression of an oncogene and a tumor suppressor from a singlegenetic locus, there is a need for evaluation of miR-33a and SREBF2 expressionstatus in prostate cancer cells to help understanding their roles in prostatecarcinogenesis. Methods. In this study, we aimed at investigating the linkbetween the expressions of miR-33a and its host gene SREBF2 and its isoforms inprostate cancer cell lines using quantitative real time PCR. We evaluated therelative expression levels with using 2- ΔΔCT method and tested thecorrelations of microRNA and gene expressions with Pearson’s Correlation testusing GraphPad Prism 6. Results. Our results demonstratedvariable expression levels for SREBF2 mRNA and miR-33a expression levels inprostate cancer cell lines, with some decreased, some increased and someunchanged. Further analysis showed a strong correlation among expressions ofSREBF2 isoforms though we could not find a significant association betweenlevels of SREBF2 isoforms and miR-33a expression. Conclusion. This datasuggest possible posttranscriptional regulation of miR-33a expression inprostate cancer.
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • The effect of obesity on functional capacity, anxiety and daily life
           activities in patients with coronary artery disease and phase II cardiac
           rehabilitation

    • Authors: Meliha Kasapoğlu Aksoy; İlknur Aykurt Karlıbel, Hasan Arı, Lale Altan
      Abstract: Objective. The aim of our study was to investigate the effect ofcardiac rehabilitation (CR) program on obese and non-obese patients withcoronary artery disease. Methods. The records of 60coronary artery disease patients aged between 18-75 years, who were included inCR were evaluated. Of the study subjects, 20 had undergone coronary arterybypass grafting (CABG) and 40 had undergone percutaneous coronary intervention(PCI). The patients weredivided into two groups by body mass index (BMI), with Group I being non-obese(BMI < 30 kg/m2) and Group 2 being obese (BMI ≥ 30 kg/m2).The effect of 30 session CR on the two groups were evaluated with 6-min walktest (6MWT), Short Form-36 (SF-36) and Beck Anxiety Inventory (BAI). Results. Baseline characteristicsof the group 1 (39 patients) and group 2 (21 patients) were similar.Statistically significant improvement was detected in group 1 and group 2patients by CR program in 6MWT, BAI and SF-36 parameters (p < 0.05). 6MWT, BAI and SF-36 parameters changes by cardiacrehabilitation were compared between the two groups. According to thecomparison 6MWT (group 1; 60 (20-183) vs group 2; 34 (15-180), p = 0.012) and MET (group 1; 1.44 ± 0.56vs group 2; 1.09 ± 0.41, p = 0.015changes were significantly higher in group 1 than in group 2. However, thechanges of BAI and SF-36 parameters were similar in two groups (p > 0.05). Conclusion. CR was foundto be effective and safe in terms of functional capacity, daily life activitiesand anxiety in both obese and non-obese patients. Functional capacity gain inthe obese group was less than non-obese patients. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Magnetic resonance imaging findings of a patient with bilateral
           submandibular gland aplasia

    • Authors: Ender Alkan; Turgay Kara, Zeynep Öztürk İnal
      Abstract: Aplasia of the major salivary glands are very rare,and commonly occurs at the parotid gland. Patients are usually asymptomatic anddiagnosed incidentally. But dry mouth, difficulty in swallowing, dentalproblems may be seen. Also mass complaints may occur due to compensatoryhypertrophy of the other major salivary glands. Herein, we presented themagnetic resonance imaging findings of a very rare case of bilateralsubmandibular gland aplasia with compensatory hypertrophy of sublingual glands. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Sensitivity of localization studies performed by various radiologists in
           the evaluation of parathyroid lesions

    • Authors: Pınar Şişman; Özen Öz Gül, Soner Cander, Ahmet Bilgehan Şahin, Çoşkun Demirtaş, Aybüke Muti, Onur Elbasan, Özlem Saraydaroğlu, Erdinç Ertürk
      Abstract: Objectives. Preoperative imaging studies are commonly used in thediagnosis of primary hyperparathyroidism to increase the success rate ofsurgery. In the present study, we aimed to correlate surgical outcomes with thesensitivity of localization studies that were performed by various radiologists. Methods. Onehundred eighty-nine patients with preoperative diagnosis primary hyperparathyroidismwere included. A total of 174 patients in whom hypercalcemia had been cured byparathyroidectomy, were evaluated retrospectively. In total, 184 lesions wereexcised from these 174 patients. Ultrasonography (USG) and technetium-99m-methoxy isobutyl isonitrile (99mTc-MIBI) imagingyielded correctly localized lesion in 74 and 108 patients, respectively. Results.The specificity of USG and 99mTc-MIBI imaging were similar (95.9%and 95.0%, respectively). However, the sensitivity was not satisfactory (45.9%for USG, 62.4% for 99mTc-MIBI). The gland size was not significantfor the rate of lesion detection by 99mTc-MIBI scan or USG.Significant differences were not observed between the preoperative serumparathormone, serum calcium or 24-hour urine calcium excretion levels and thesuccess rate of localization with either USG or 99mTc-MIBI. Conclusions.Radiologist experience in ultrasonographic parathyroid imaging was found toaffect sensitivity. Therefore, surgeons, radiologists and endocrinologists thatperform ultrasonographic evaluation should have extensive experience. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Effect of functional endoscopic sinus surgery on asthma control with nasal
           polyposis and chronic rhinosinusitis

    • Authors: Önder Akdeniz; Seyhan Dülger, Dilber Yılmaz Durmaz, Özlem Şengören Dikiş, Tekin Yıldız
      Abstract: Objective.The purpose of this study is to examine the effect of endoscopic sinus surgeonson the control of disease in asthma combined with chronic rhinosinusitis. Methods.Twenty-three asthma patients with chronic rhinosinusitis were evaluatedretrospectively. They were assessed with asthma control test and pulmonaryfunction tests. Subjective nasal obstruction assessment was done according tothe nasal obstruction symptoms evaluation (NOSE) scale. Other subjectivesinonasal complaints were classified using visual analogue scale (VAS). At postoperativethird month, pulmonary function tests, asthma control test, NOSE and VAS werereevaluated. Results. According to asthma control test, number of patientsunder control, partial controlled and uncontrolled were 2/6/15 preoperatively and14/4/5 postoperatively, respectively. There was permanent or partialimprovoment in fullness in the nose sniffle of 95.7% according to NOSE. Themost remarkable permanent improvement in the symptoms were seen in the feelingof pressure in the face of 75%, smell disorders of 66.7% according to sinonasalvisual analogue scale assessment. NOSE and VAS values were significantlyimproved postoperatively (p <0.05). Conclusions. Uncontrolled asthma associated with chronicrinosinusitis can benefit from functional endoscopic sinus surgery in asthmacontrol level, nasal blockage symptoms and other sinonasal complaints.
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • In vitro transfection potential of fluorinated G5 PAMAM dendrimers for
           miRNA delivery to MRC-5 cells

    • Authors: Ali Öztuna; Hasan Nazır
      Abstract: Objectives. MicroRNAs (miRNAs) are involved in the regulation ofmost biological processes and also contribute to many types of disease.Fibroblast cells, such as MRC-5, are often used in biological researchesutilizing cell transfection methods due to their difficult to transfect nature.Cells can be genetically engineered by using viral and non-viral methods.Poly(amidoamine) (PAMAM) dendrimers are very promising alternative as adelivery vehicle due to their well-definedcharacteristics. In this study, in vitrotransfection potential of cystamine core generation five (G5) PAMAM dendrimersfluorinated with 2,3,4,5,6-pentafluorobenzoic acid (PFB) and pentafluoropropionicacid (PFP) for miRNA delivery to MRC-5 cells was examined. Methods. Spectroscopictechniques were used in the characterization of the prepared dendrimers. miRNAbinding and condensation capability of dendrimers was examined by gelretardation assay. Characterization of dendriplexes was made by zeta potential,particle size measurements and transmission electron microscopy. Transfectionefficiencies of the dendriplexes were determined by flow cytometry andintracytoplasmic distribution of the dendriplexes was shown by laser scanningconfocal microscopy. Also, quantitative structure-activity relationship and moleculardocking calculations were used to be able to discuss transfection efficienciesof the dendriplexes into the cell. Results. While high level of viabilityon MRC-5 cells was observed for dendriplexes prepared with PFB and PFP,transfection efficiency with PFP was higher than PFB. Transfection efficiencydifference between these two compounds was attributed to their molecularstructures. Conclusions. Obtained results hold promise for the usage ofthese compounds as a transfection reagent at MRC-5 cells. Further studies areneeded to support these findings. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • The frequency of toll-like receptor 4 gene polymorphism in ankylosing
           spondylitis and its relationship between disease activity

    • Authors: Betül Sargın; Ayla Akbal, Hatice Resorlu, Yılmaz Savaş, Coşkun Zateri, Fatma Sılan, Öztürk Özdemir
      Abstract: Objectives. We aimed to evaluate the frequency of toll-likereceptor 4 (TLR4) gene polymorphism and its relationship between diseaseactivity in patients with ankylosing spondylitis (AS). Methods. Forty-one AS patients (25 male/16female) fullfilling the 1984 Modified New York Criteria and 41healthycontrols (25 male/16female) were included in this study. Disease activity of the AS patients wasassesed by Bath Ankylosing Spondylitis Disease Activity Index (BASDAI). The TLR4 gene polymorphism of AS patients and healthy controls were analyzed byReal-Time Polymerase Chain Reaction (PCR) System. Results.Three (7.3%) patients with AS had TLR4 gene polymorphism compared with healthycontrols (0/41; 0%). Two of these patients had heterozygous mutation and onehad homozygous mutation. Significant correlation was not found between TLR4gene polymorphism and BASDAI score (p> 0.05). Conclusions. In our study, TLR4gene polymorphism was higher in patients with AS compared with control group. But,this polymorphism was not associated with disease activity, erythrocyte sedimentation rate and C-reactive proteinlevels.
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Personnel radiation dose assessment using a novel dosimeter in the
           department of radiology and dentistry in a medical facility in Delta
           State, South-South Nigeria: Our experience in the last 4 years

    • Authors: Akintayo Daniel Omojola; Michael Onoride Akpochafor, Samuel Olaolu Adeneye, Ukeme Pius Aniekop, Margaret Idongesit Anizor, Mary-Ann Etim Ekpo, Chibuzor Bede Madu
      Abstract: Objectives. Large percentagesof X-ray facilities in Nigeria do not use radiation monitoring device; a fewpercentage that use them do not evaluate or carryout out assessment programs toascertain the detriment to occupationally exposed workers. This study was aimedat evaluating dose reports from 2013 to 2016 for personnel who operate  radiation facilities and those that workwithin radiation field during certain X-ray procedures/examinations in thedepartment of radiology and dentistry respectively; to ascertain if there iscorrelation between personnel dose and workload in both department and todetermine if dose records are within acceptable limit recommended by theinternational atomic energy agency (IAEA) safety series. Methods. Direct ion storage (DIS) dosimeter wasused for a total of 35 occupationally exposed personnel who work in thedepartment of radiology and dentistry. The DIS dosimeter was read every twomonths and results were authomatically saved on the instadoseTMplatform. Results. The mean (total) dose in radiology department for thefirst, second, third and fourth year was 0.17 ± 0.08 (3.52) mSv, 0.08 ± 0.03(0.77) mSv, 0.07 ± 0.04 (0.72) mSv and 0.07 ± 0.05 (0.55) mSv and in Dentistrywas 0.08 ± 0.02 (0.73) mSv, 0.05 ± 0.02 (0.42) mSv, 0.05 ± 0.02 (0.24) mSv and0.07 ± 0.04 (0.34) mSv; respectively. There was significant difference in meanpersonnel dose from 2013-2016 in Radiology (p= 0.028) and in Dentistry Department (p= 0.004). Correlation of workload and personnel dose inRadiology (p = 0.240) and DentistryDepartment (p = 0.765) wasn’tsignificant. There was nocorrelation in mean dose between both department (p = 0.256). Conclusion. Overall mean dose inboth department for occupationally exposed personnel werebelow IAEA annual dose limit of 20 mSv averaged over a period of 5consecutive years. Dose reports ofpersonnel in both department reduced as the year progressed due to radiationsafety awareness.
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • How to diagnose neuropathy in diabetes mellitus'

    • Authors: Abdulkadir Koçer
      Abstract: Diabetic neuropathy is a common problem and canpresent various clinical presentations such as cranial neuropathy,radiculopathy, plexopathy, mononeuropathy, polyneuropathy and autonomicneuropathy. Clinical evaluation and use of scoring systems for the evaluation ofdiabetic polyneuropathy is an important step to get correct diagnosis. Newinformations about the diagnosis of diabetic neuropathy continue to emerge,which will lead to correct diagnosis and treatment as well. Diabetic length-dependentsensorimotor polyneuropathy (DSPN) and carpal tunnel syndrome are the mostcommon seen problems. While acuteand painful situations with motor weakness are mostly transient, sensory fibresare predominantly involved in chronic ones. Nerve conduction studies areneeded to confirm diagnosis of any type of diabetic neuropathy, but they arenormal in cases with small fiber involvement. The early diagnosis is crucial because it is well-known thatsubclinical diabetic neuropathy may be reversed or significantly improved withdiabetes control. Because neuropathy at the stagein which only small fibers are affected can be reversed, it is important todiagnose DSPN in these stages. Skin biopsy taken from the dermatomal area ofsural nerve, laser-doppler-imagerflare technique, corneal confocal microscopy are used to assess small fibre dysfunction. The aim ofthe present review was to evaluate evidence-based diagnosis for any type ofneuropathy seen in the patients with diabetes mellitus.
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • An arteriovenous malformation as a rare cause of sciatic neuropathy: a
           case report

    • Authors: Ezgi Akar; Mustafa Akgün, Mehmet Ufuk Akmil
      Abstract: Sciatica is characterized by pain and discomfortoccurring frequently with impingement at the level of spinal nerve along theregions innervated by the sciatic nerve. Compression and irritation of thenerve often occurs with a spinal cause such as lumbar disc hernia or spinalstenosis. Compression of the nerve by an arteriovenousmalformation is very rare among thecauses leading to nondiscogenic sciatic neuropathy. Herein, we reported ourcase with clinically and electrophysiologically typical sciatic neuropathy andtreated by us surgically. To our knowlodge, cases with arteriovenous malformation -caused sciatica werelimited in the literature review. Electromyography should be performed to exclude the nervecompression due to rare causes such as vascular causes which may lead tosciatic neuropathy in patients with sciatic distribution symptoms and signs,after initial negative spine imaging. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Metachronous infiltration of bone marrow due to breast cancer and multiple
           myeloma

    • Authors: Ahmet Peker; Hakan Yarkıcı, Mehmet Can Uğur, Harun Akar, Cengiz Ceylan, Dudu Solakoğlu Kahraman
      Abstract: Multiple primary tumors are rarely seen in clinicalpractice. Cases of metastatic breast cancer associated with multiple myelomawere rare in the literature. It is believed that simultaneously observed bonemarrow involvement due to breast cancer and multiple myeloma is sporadic. Wepresent a 49-year-old female patient with metastatic breast cancer who developedmultiple myeloma during breast cancer treatment. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Pedunculated liver hemangioma mimicking stomach neoplasm

    • Authors: Sonay Aydın; Erdem Fatihoğlu, Elif Ergün, Pınar Nercis Koşar
      Abstract: Hepatic hemangiomas are the most frequently seenbenign liver mass. However, exophytic hepatic hemangiomas, particularlypedunculated ones are very rare. They have various appearances that make thediagnosis difficult. We report a pedunculated hemangioma case which wasmisdiagnosed as gastrointestinal stromal tumor on computerized tomography scan.Magnetic resonance imaging revealed that the tumor was a hepatic hemangiomawith a long peduncle originating from the right edge of the liver, extendinginto perigastric area. Hepatic hemangioma with a long peduncle can be mistakenwith other abdominal masses. Remembering this entity and knowing its imagingcharacteristics are the keys to diagnosis. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Left atrial myxoma combined with coronary artery disease in an elderly
           patient

    • Authors: Gündüz Yümün; Selami Gürkan, Okan Donbaloğlu
      Abstract: Cardiac myxomaassociated with coronary artery disease is a rare pathology in an elderlypatient. Herein we present an 81-year-old woman undergoing simultaneous surgicaltreatment for left atrial myxoma combined with coronary artery disease. Thepostoperative course of the patient was uneventful. The initial removal of massshould be performed to prevent systemic embolization of tumor fragments. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
  • Borderline Brenner tumor with a concomitant mucinous tumor of the ovary: a
           case report

    • Authors: Hülya Ayık Aydın; Zeynep Bayramoğlu, Armağan Aydın, Hadice Elif Pestereli, Tayup Şimşek
      Abstract: Brennertumors (BTs) are rare ovarian tumors which are a part of the epithelial stromaltumor group of ovarian neoplasms. Most of the BTs are benign and usuallyasymptomatic. BTs stand for the 1.4-2.5% of ovariantumors. Of the BTs, not more than 2% exhibit characteristics of borderline (ormalignant) BTs. Borderline BTs are usually bigger than benign BTs andindividuals typically represent with symptoms related with an unilateralovarian mass. BTs are often related with mucinous cystadenomas or seldomlycystadenocarcinomas. We present a case of borderline BT associated with aconcomitant mucinous ovarian tumor. 
      PubDate: Wed, 04 Apr 2018 00:00:00 +030
       
 
 
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