Subjects -> MEDICAL SCIENCES (Total: 8697 journals)
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MEDICAL SCIENCES (2419 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access   (Followers: 3)
3D Printing in Medicine     Open Access   (Followers: 5)
4 open     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 6)
AAS Open Research     Open Access   (Followers: 2)
ABCS Health Sciences     Open Access   (Followers: 8)
Abia State University Medical Students' Association Journal     Full-text available via subscription   (Followers: 3)
AboutOpen     Open Access  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Hybrid Journal   (Followers: 50)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access  
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Científica Estudiantil     Open Access  
Acta Facultatis Medicae Naissensis     Open Access   (Followers: 1)
Acta Herediana     Open Access  
Acta Informatica Medica     Open Access   (Followers: 2)
Acta Medica (Hradec Králové)     Open Access  
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta Medica International     Open Access  
Acta medica Lituanica     Open Access   (Followers: 1)
Acta Medica Marisiensis     Open Access   (Followers: 1)
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access   (Followers: 1)
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access   (Followers: 3)
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 8)
Acupuncture and Natural Medicine     Open Access  
Addiction Science & Clinical Practice     Open Access   (Followers: 9)
Addictive Behaviors Reports     Open Access   (Followers: 9)
Adıyaman Üniversitesi Sağlık Bilimleri Dergisi / Health Sciences Journal of Adıyaman University     Open Access   (Followers: 1)
Adnan Menderes Üniversitesi Sağlık Bilimleri Fakültesi Dergisi     Open Access   (Followers: 1)
Advanced Biomedical Research     Open Access  
Advanced Health Care Technologies     Open Access   (Followers: 10)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 9)
Advanced Therapeutics     Hybrid Journal   (Followers: 1)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 7)
Advances in Cell and Gene Therapy     Hybrid Journal   (Followers: 1)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 27)
Advances in Clinical Radiology     Full-text available via subscription   (Followers: 3)
Advances in Life Course Research     Hybrid Journal   (Followers: 11)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Medical Education and Practice     Open Access   (Followers: 32)
Advances in Medical Ethics     Open Access   (Followers: 5)
Advances in Medical Research     Open Access   (Followers: 2)
Advances in Medical Sciences     Hybrid Journal   (Followers: 10)
Advances in Medicinal Chemistry     Full-text available via subscription   (Followers: 6)
Advances in Medicine     Open Access   (Followers: 3)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 5)
Advances in Molecular Oncology     Open Access   (Followers: 2)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 7)
Advances in Parkinson's Disease     Open Access   (Followers: 2)
Advances in Phytomedicine     Full-text available via subscription   (Followers: 1)
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 21)
Advances in Regenerative Medicine     Open Access   (Followers: 4)
Advances in Skeletal Muscle Function Assessment     Open Access  
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Traditional Medicine     Hybrid Journal   (Followers: 8)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 15)
Advances in Virus Research     Full-text available via subscription   (Followers: 6)
Advances in Wound Care     Hybrid Journal   (Followers: 14)
Aerospace Medicine and Human Performance     Full-text available via subscription   (Followers: 13)
African Health Sciences     Open Access   (Followers: 5)
African Journal of Biomedical Research     Open Access   (Followers: 1)
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 4)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 3)
African Journal of Thoracic and Critical Care Medicine     Open Access  
African Journal of Trauma     Open Access   (Followers: 1)
Afrimedic Journal     Open Access   (Followers: 3)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 9)
AJOB Empirical Bioethics     Hybrid Journal   (Followers: 3)
AJSP: Reviews & Reports     Hybrid Journal   (Followers: 1)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 6)
Al-Azhar Assiut Medical Journal     Open Access   (Followers: 2)
Al-Qadisiah Medical Journal     Open Access   (Followers: 1)
Alerta : Revista Científica del Instituto Nacional de Salud     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 3)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 2)
Althea Medical Journal     Open Access   (Followers: 2)
American Journal of Biomedical Engineering     Open Access   (Followers: 15)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 7)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 4)
American Journal of Clinical Medicine Research     Open Access   (Followers: 8)
American Journal of Family Therapy     Hybrid Journal   (Followers: 10)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 7)
American Journal of Managed Care     Full-text available via subscription   (Followers: 13)
American Journal of Medical Case Reports     Open Access   (Followers: 3)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 5)
American Journal of Medicine     Hybrid Journal   (Followers: 50)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access   (Followers: 3)
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 11)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 6)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 5)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 7)
Anatolian Clinic the Journal of Medical Sciences     Open Access  
Anatomica Medical Journal     Open Access  
Anatomical Science International     Hybrid Journal   (Followers: 3)
Anatomical Sciences Education     Hybrid Journal   (Followers: 2)
Anatomy     Open Access   (Followers: 3)
Anatomy Research International     Open Access   (Followers: 4)
Androgens : Clinical Research and Therapeutics     Open Access   (Followers: 1)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Ankara Medical Journal     Open Access   (Followers: 2)
Ankara Üniversitesi Tıp Fakültesi Mecmuası     Open Access  
Annales de Pathologie     Full-text available via subscription  
Annales des Sciences de la Santé     Open Access  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 2)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 3)
Annals of Bioanthropology     Open Access   (Followers: 5)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 19)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 4)
Annals of Clinical Hypertension     Open Access  
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 15)
Annals of Family Medicine     Open Access   (Followers: 18)
Annals of Health Research     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 7)
Annals of Medicine and Surgery Case Reports     Open Access   (Followers: 1)
Annals of Medicine and Surgery Protocols     Open Access   (Followers: 1)
Annals of Microbiology     Hybrid Journal   (Followers: 13)
Annals of Musculoskeletal Medicine     Open Access   (Followers: 2)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Rehabilitation Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the College of Medicine, Mosul     Open Access   (Followers: 1)
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annals of the RussianAacademy of Medical Sciences     Open Access   (Followers: 1)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 5)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 25)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Reports     Open Access   (Followers: 1)
Antibody Technology Journal     Open Access   (Followers: 1)
Antibody Therapeutics     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 2)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 5)
Applied Clinical Research, Clinical Trials and Regulatory Affairs     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 14)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arabian Journal of Scientific Research / المجلة العربية للبحث العلمي     Open Access   (Followers: 1)
Archive of Biomedical Science and Engineering     Open Access   (Followers: 1)
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access   (Followers: 1)
Archives Medical Review Journal / Arşiv Kaynak Tarama Dergisi     Open Access  
Archives of Asthma, Allergy and Immunology     Open Access  
Archives of Clinical Hypertension     Open Access   (Followers: 2)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 5)
Archives of Medicine and Surgery     Open Access   (Followers: 1)
Archives of Organ Transplantation     Open Access   (Followers: 2)
Archives of Preventive Medicine     Open Access   (Followers: 3)
Archives of Pulmonology and Respiratory Care     Open Access   (Followers: 2)
Archives of Renal Diseases and Management     Open Access   (Followers: 2)
Archives of Trauma Research     Open Access   (Followers: 4)
Archivos de Medicina (Manizales)     Open Access   (Followers: 1)
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access   (Followers: 1)
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access   (Followers: 1)
Ars Medica : Revista de Ciencias Médicas     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Hybrid Journal   (Followers: 19)
Arterial Hypertension     Open Access   (Followers: 1)
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 20)
Artificial Organs     Hybrid Journal   (Followers: 1)
ASHA Leader     Open Access   (Followers: 6)
Asia Pacific Family Medicine Journal     Open Access   (Followers: 4)
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 13)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access   (Followers: 1)

        1 2 3 4 5 6 7 8 | Last

Similar Journals
Journal Cover
Acta Medica International
Journal Prestige (SJR): 0.101
Number of Followers: 0  

  This is an Open Access Journal Open Access journal
ISSN (Print) 2349-0578 - ISSN (Online) 2349-0896
Published by Medknow Publishers Homepage  [427 journals]
  • A report on the requirements of rigorous research

    • Authors: Sanjeev Kumar Jain, Ummi Afifa, Sonika Sharma
      Pages: 1 - 2
      Abstract: Sanjeev Kumar Jain, Ummi Afifa, Sonika Sharma
      Acta Medica International 2020 7(1):1-2

      Citation: Acta Medica International 2020 7(1):1-2
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_44_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • Tryptase: A novel prognostic biomarker in chronic myeloid leukemia

    • Authors: Anisha Mathew, Manisha Naithani, Uttam Kumar Nath
      Pages: 3 - 6
      Abstract: Anisha Mathew, Manisha Naithani, Uttam Kumar Nath
      Acta Medica International 2020 7(1):3-6
      Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm characterized by the presence of the Philadelphia chromosome. It is treated with tyrosine kinase inhibitor agents targeted against the breakpoint cluster region-Abelson murine leukemia 1 fusion transcript. Disease risk stratification at diagnosis of chronic-phase (CP) CML is done using Sokal, Hasford, and EUTOS scores which use basophilia as a major component. However, basophil counts can be both variable and inaccurate. The serum tryptase level is being studied as a novel biomarker which represents the total basophil compartment. Tryptase, deriving its name from trypsin-like activity commonly expressed by mast cells, and also by immature basophils of patients suffering from various myeloid and leukemic disorders, has a role in tumor proliferation. Patients with seemingly low-normal levels of basophils and raised tryptase levels progress further in disease despite treatment. There is a recent interest in the role of serum tryptase as a prognostic marker in CML-CP.
      Citation: Acta Medica International 2020 7(1):3-6
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_41_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • A clinicopathological analysis of bone and soft tissue sarcoma in children
           and young adults: Time to adapt with the rapidly changing landscape?

    • Authors: Abhishek Basu, Debottam Barman, Shinjini Chakrabarty, Janmenjoy Mondal, Bhukya Swetha, Ansuman Bhattacharjee, Ipsita Chakraborty
      Pages: 7 - 12
      Abstract: Abhishek Basu, Debottam Barman, Shinjini Chakrabarty, Janmenjoy Mondal, Bhukya Swetha, Ansuman Bhattacharjee, Ipsita Chakraborty
      Acta Medica International 2020 7(1):7-12
      Context: Primary bone and soft-tissue sarcomas (STSs) are rare tumors, comprising <1% of overall adult cancers. Despite its heterogeneous molecular profile, multimodality management of these tumors has led to the 5-year overall survival (OS) benefit, from approximately 50% in 1970 to the range of 75%–80% presently, in the adolescent age group. Various hospital-based registries have tried to address the scarcity of data of bone and STSs in Indian context in the last decade, but the number is not encouraging enough to gauge the pattern of care of the disease in children and young adults. Aims: To analyze the predictive and prognostic factors of clinical outcome in bone and STS in children and young adults. Settings and Design: This was a retrospective, single-institutional study from a prospectively maintained database. Subjects and Methods: We enrolled biopsy-proven patients (aged 3–35 years) of bone and STS, attended at our outpatient department during the period of January 2015 to December 2017 and traced till November 2019. Follow-up time was defined by the period from the date of registration to the date of last attendance or death. Statistical Analysis Used: Univariate log-rank analysis and unpaired t-test were used to assess the potential prognostic factors for progression-free survival and OS and further validated by multivariate Cox regression analyses. Results: Tumor size, stage at presentation, and treatment modality were the significant prognostic factors for both bone and STS. Children had better OS with 3-year OS (89.7% vs. 71.8%). Conclusions: We recommend multidisciplinary management with emphasis on early intervention in these tumors.
      Citation: Acta Medica International 2020 7(1):7-12
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_26_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • Caregiver burden and quality of life in primary caregivers of
           schizophrenia patients: A cross-sectional study from a tertiary care
           hospital

    • Authors: Bilal Ahmad Bhat, Shabir Ahmad Dar, Rouf Ahmad Mir, Arshad Hussain
      Pages: 13 - 18
      Abstract: Bilal Ahmad Bhat, Shabir Ahmad Dar, Rouf Ahmad Mir, Arshad Hussain
      Acta Medica International 2020 7(1):13-18
      Background: With a shift in treatment and care of schizophrenia over the years, with more and more patients being treated on an outpatient basis and cared in community, caregivers experience distress in psychological and emotional health, have reduced social contact, have financial difficulties, have low life satisfaction, and have poor mental and physical health. Aims: The aim is to understand the quality of life (QoL) and the extent of burden perceived by caregivers while caregiving a family member with a diagnosis of schizophrenia. Materials and Methods: This was a cross-sectional study. A total of 75 schizophrenia patients and their caregivers were included in this study. Standardized instruments were administered to patients as well as to caregivers to collect data regarding symptomatology in patients and perceived burden and QoL in their caregivers. Results: The mean age of caregivers was 40.49 ± 12.65 years, and of patients was 37.45 ± 9.55. The mean score on the Schizophrenia Caregiver Quality of Life (S-CGQoL) questionnaire was 44.8 ± 8.67. 76% of caregivers had a score <50. QoL was significantly correlated with burden on caregivers (r = −0.478; P = 0.0001) and duration of illness of patients (r = 0.243; P = 0.014). The mean score on Zarit Burden Interview (ZBI) was 38.28% ±11.19. 64% of caregivers perceived mild-to-moderate burden. Caregivers burden was correlated with manifestation of negative symptoms in patients (r = 0.287; P = 0.013). Negative symptom scores significantly predicted the burden perceived by caregivers. Conclusion: Caregivers of schizophrenia patients experience a considerable level of burden which with significant correlations between negative symptoms in patients and scores on ZBI. Negative symptoms in patients were the only predictor of the burden on caregivers. Low QoL with a score of <50 on S-CGQoL was present in two-thirds of caregivers. QoL was related positively to the duration of illness and negatively to the burden on caregivers.
      Citation: Acta Medica International 2020 7(1):13-18
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_21_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • Introduction of module on informed consent training for interns during
           compulsory surgery rotation

    • Authors: Rajneesh Kumar, Tania Moudgil, Rajiv Arora, Ankita Attri, Sahil Singh
      Pages: 19 - 30
      Abstract: Rajneesh Kumar, Tania Moudgil, Rajiv Arora, Ankita Attri, Sahil Singh
      Acta Medica International 2020 7(1):19-30
      Background: The use of consent in patient care is a critical skill it is as essential as any other basic standard on which surgical exercise relies. In the present study, an effort was made to formulate a module for training interns on this skill. Materials and Methods: After taking permission from IEC, 140 interns were enrolled for the study. After needs assessment, a module for training the interns for taking informed consent in all scenarios was prepared and validated. Interns were assessed using directly observed procedural skill (DOPS). Feedback was taken from interns and faculty on training through this module at the end of their posting. Results: A total of 140 interns undertook 3 DOPS each and all the interns performed: nonsatisfactory in DOPS 1 (below 4 in each subcompetency), satisfactorily in DOPS 2 (4–6 in each subcompetency), and satisfactorily in DOPS 3 (6–8). Comparison of DOPS 1, 2, and 3 done was done using repeated measure ANOVA and P value was highly statistically significant (P = 0.000). Comparison of progression of scores showed statistically significant P value (P = 0.000). Conclusion: DOPSs is an effective and feasible assessment tool for assessing interns for taking informed consent.
      Citation: Acta Medica International 2020 7(1):19-30
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_11_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • An online survey on practice and opinion on preoperative viral serology
           testing among anesthesiologists, surgeons, and public health professionals
           

    • Authors: Tuhin Mistry, Habib Md Reazaul Karim
      Pages: 31 - 38
      Abstract: Tuhin Mistry, Habib Md Reazaul Karim
      Acta Medica International 2020 7(1):31-38
      Background and Objectives: Currently, there is no recommendation or guideline on routine preoperative viral serology testing. This online questionnaire-based survey was conducted to explore the current practice and opinion across the country (India). Methodology: After obtaining permission from the investigators' affiliated institute, a set of 12 questions with multiple choices was sent to the anesthesiologists, surgeons, and public health professionals using the Google Form. The participants anonymously completed this online-based questionnaire. The responses were downloaded in the Excel format and further expressed in absolute number and percentage scale. Interprofessional comparisons were made using Fisher's exact test (INSTAT software from GraphPad Prism Software Inc., La Jolla, CA, USA), and P < 0.05 was considered statistically significant. Results: A total of 1157 e-mails were sent, of which 216 bounced; 22.8% of the remaining responded, the majority (76.3%) were anesthesiologists. One-hundred and eighty-seven (89.9%) responders opined for routine preoperative viral testing: 182 (87.5%) were practicing, while 142 out of the 206 (68.9%) of the responders' hospitals had a protocol in place. Compared to the opinions of public health administrators/community physicians, no statistically significant difference (all P > 0.05) was found between the anesthesiologists and the surgeons. Even the anesthesiologists, as well as the surgeons, had similar opinions and practices (all P > 0.05) except the anesthesiologists who were having statistically significantly higher knowledge about the inability to detect case by serology testing during the window period (P = 0.02). Conclusion: Preoperative viral (hepatitis B virus surface antigen, anti-hepatitis C virus, and human immunodeficiency virus I and II) testing is very rampant as routine, and nine out of ten practitioners opine for the mandatory routine practice in India.
      Citation: Acta Medica International 2020 7(1):31-38
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_38_19
      Issue No: Vol. 7, No. 1 (2020)
       
  • The effect of malaria-induced serum tumor necrosis factor-alpha on
           epiphyseal bone formation of rats

    • Authors: Ato Ampomah Brown, Leonard Derkyi-Kwarteng, Chrissie Stansie Abaidoo
      Pages: 39 - 43
      Abstract: Ato Ampomah Brown, Leonard Derkyi-Kwarteng, Chrissie Stansie Abaidoo
      Acta Medica International 2020 7(1):39-43
      Aim: Malaria infection has long been associated with stunted growth in children and by extension bone formation. There is, however, a paucity of information on the specific factors or substances that are responsible for this observation. The objective of this study was, therefore, to find out whether malaria-induced tumor necrosis factor-alpha (TNF-α) influenced in any way the formation of the epiphyseal bone layer of Sprague Dawley rats. Materials and Methods: Thirty-two Sprague Dawley rats aged 4 weeks were used in this study, and the animals were randomly allocated to four groups (Group A–D), with each group having 8 animals. Animals in Group A were given oral artemether/lumefantrine combination drug only, animals in Group B were inoculated with Plasmodium berghei (NK65) only, those in Group C were inoculated with P. berghei (NK65) and treated with oral artemether/lumefantrine, while animals in Group D were neither inoculated with the malaria parasite nor given artemether/lumefantrine therapy. Blood was drawn from the animals at predetermined intervals to measure serum TNF-α levels. Results: Recurrent bouts of murine malaria caused serum TNF-α levels to be significantly elevated even after the infected animals were successfully treated. The elevated serum TNF-α levels were found to correlate with the amount of bone tissue deposited at the distal femoral epiphysis. Conclusion: Malaria-induced TNF-α most likely delays bone tissue formation and may be a major contributing factor in the development of stunted growth in children.
      Citation: Acta Medica International 2020 7(1):39-43
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_10_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • Role of diffusion tensor imaging scores in patients with spinal trauma

    • Authors: Ankur Malhotra, Mohini Chaudhary, Arjit Agarwal, Shruti Chandak, Deepak Singla
      Pages: 44 - 50
      Abstract: Ankur Malhotra, Mohini Chaudhary, Arjit Agarwal, Shruti Chandak, Deepak Singla
      Acta Medica International 2020 7(1):44-50
      Background: Many patients of spinal trauma who have an apparently normal conventional magnetic resonance imaging (MRI) scan ultimately progress to neurological degradation in the long run. Diffusion tensor imaging (DTI) can play a vital role in such patients and can be used to assess the true extent of injury. Aims: The aims are to study the utility of DTI in detecting abnormalities in patients with spinal cord trauma and to obtain DTI scores. Materials and Methods: The study comprised 30 individuals including 20 cases and 10 apparently healthy controls who underwent conventional MRI, followed by DTI of involved spine. Fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values were obtained by planning three regions of interest in the spinal cord at, above, and below the level of trauma. Results: Signal changes in the cord on conventional MRI were seen in 8 cases and were absent in 12. A significant difference was observed in mean FA values at the level of injury in cases without any change in signal intensity in the cord on conventional MRI (0.391 ± 0.12) as compared to controls (0.65 ± 0.165) as well as in mean ADC values in cases (1.534 ± 0.511) and controls (1.132 ± 0.616). Conclusions: DTI is an invaluable modality in assessment of the spinal cord following traumatic injury because it can detect subtle disruption of white matter leading to significant difference in the FA and ADC values.
      Citation: Acta Medica International 2020 7(1):44-50
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_22_20
      Issue No: Vol. 7, No. 1 (2020)
       
  • Rhombencephalitis secondary to toxoplasma gondii infection: Case report
           and literature review

    • Authors: Jamir Pitton Rissardo, Ana Let&#237;cia Fornari Caprara, Juliana Oliveira Freitas Silveira
      Pages: 51 - 54
      Abstract: Jamir Pitton Rissardo, Ana Letícia Fornari Caprara, Juliana Oliveira Freitas Silveira
      Acta Medica International 2020 7(1):51-54
      Immunocompetent (IC) individuals with primary toxoplasmosis are usually asymptomatic. However, in some IC, toxoplasmosis can present with brainstem encephalitis. We report an adult female patient with headache associated with worsening coordination. Physical examination showed bilateral, symmetrical, and nontender cervical lymphadenopathy. Toxoplasmosis immunoglobulin G (IgG) and IgM were high, and the IgG antibody avidity pattern was low. The cerebrospinal fluid analysis was requested that revealed a positive polymerase chain reaction results for toxoplasmosis. A brain magnetic resonance imaging (MRI) showed a T1-hypointense left pontine lesion. Pyrimethamine and sulfadiazine were started. After 1 month, the patient had full recovery. Four months after, the individual was admitted due to progressive abnormal eye movements and tremor. Her neurological examinations showed ocular myoclonus and Holmes tremor. A second brain MRI showed hypertrophy of the ipsilateral inferior olivary nucleus. In the follow-up, her symptoms decreased mildly. The tremor was managed with clonazepam and levodopa. Furthermore, immune suppression investigation was negative.
      Citation: Acta Medica International 2020 7(1):51-54
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/ami.ami_78_19
      Issue No: Vol. 7, No. 1 (2020)
       
  • Retraction: Oxidative stress and biomarker of tumor necrosis factor alpha,
           malondialdehyde, and ferric reducing antioxidant power in hypertension

    • Pages: 55 - 55
      Abstract:
      Acta Medica International 2020 7(1):55-55

      Citation: Acta Medica International 2020 7(1):55-55
      PubDate: Thu,11 Jun 2020
      DOI: 10.4103/2349-0578.274681
      Issue No: Vol. 7, No. 1 (2020)
       
 
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