Subjects -> MEDICAL SCIENCES (Total: 8529 journals)
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MEDICAL SCIENCES (2342 journals)            First | 3 4 5 6 7 8 9 10 | Last

Showing 1201 - 1400 of 3562 Journals sorted alphabetically
Journal of Health Research and Reviews     Open Access  
Journal of Health Science and Medical Research     Open Access  
Journal of Health Science Research     Open Access  
Journal of Health Sciences     Open Access   (Followers: 1)
Journal of health sciences     Open Access  
Journal of Health Sciences / Sağlık Bilimleri Dergisi     Open Access  
Journal of Health Sciences and Medicine     Open Access  
Journal of Health Sciences and Surveillance System     Open Access  
Journal of Health Sciences Scholarship     Open Access  
Journal of Health Specialties     Open Access  
Journal of Health Studies     Open Access  
Journal of Healthcare Informatics Research     Hybrid Journal   (Followers: 1)
Journal of Heavy Metal Toxicity and Diseases     Open Access  
Journal of Helminthology     Hybrid Journal   (Followers: 2)
Journal of Herbs Spices & Medicinal Plants     Hybrid Journal  
Journal of HIV for Clinical and Scientific Research     Open Access   (Followers: 1)
Journal of Hospital Medicine     Hybrid Journal   (Followers: 10)
Journal of Huazhong University of Science and Technology [Medical Sciences]     Hybrid Journal  
Journal of Human Hypertension     Hybrid Journal   (Followers: 3)
Journal of Human Rhythm     Open Access  
Journal of Human Transcriptome     Open Access  
Journal of Ideas in Health     Open Access  
Journal of Inflammation     Open Access   (Followers: 2)
Journal of Inflammation Research     Open Access  
Journal of Injury and Violence Research     Open Access   (Followers: 7)
Journal of Innovation in Health Informatics     Open Access   (Followers: 17)
Journal of Institute of Medicine     Open Access  
Journal of Insulin Resistance     Open Access   (Followers: 1)
Journal of Interactional Research in Communication Disorders     Hybrid Journal   (Followers: 5)
Journal of Interferon & Cytokine Research     Hybrid Journal   (Followers: 3)
Journal of International Medical Research     Open Access   (Followers: 4)
Journal of Interventional Medicine     Open Access   (Followers: 1)
Journal of Investigative Medicine     Hybrid Journal   (Followers: 3)
Journal of Islamabad Medical & Dental College     Open Access  
Journal of Istanbul Faculty of Medicine     Open Access  
Journal of Karnali Academy of Health Sciences     Open Access   (Followers: 1)
Journal of Kathmandu Medical College     Open Access   (Followers: 1)
Journal of King Abdulaziz University : Medical Sciences     Open Access   (Followers: 2)
Journal of Laboratory Medicine     Hybrid Journal   (Followers: 27)
Journal of Laryngology and Voice     Open Access   (Followers: 11)
Journal of Lasers in Medical Sciences     Open Access  
Journal of Law, Medicine & Ethics     Hybrid Journal   (Followers: 24)
Journal of Legal Medicine     Hybrid Journal   (Followers: 7)
Journal of Limb Lengthening & Reconstruction     Open Access  
Journal of Lumbini Medical College     Open Access   (Followers: 1)
Journal of Mahatma Gandhi Institute of Medical Sciences     Open Access  
Journal of Manipulative and Physiological Therapeutics     Hybrid Journal   (Followers: 6)
Journal of Manmohan Memorial Institute of Health Sciences     Open Access   (Followers: 1)
Journal of Marine Medical Society     Open Access  
Journal of Materials Science : Materials in Medicine     Hybrid Journal   (Followers: 4)
Journal of Maternal and Child Health     Open Access  
Journal of Mechanics in Medicine and Biology     Hybrid Journal  
Journal of Medical and Biological Engineering     Hybrid Journal   (Followers: 4)
Journal of Medical and Biomedical Sciences     Open Access   (Followers: 2)
Journal of Medical Case Reports     Open Access   (Followers: 1)
Journal of Medical Cases     Open Access   (Followers: 6)
Journal of Medical Colleges of PLA     Full-text available via subscription  
Journal of Medical Disorders     Open Access  
Journal of Medical Economics     Hybrid Journal   (Followers: 8)
Journal of Medical Education and Curricular Development     Open Access   (Followers: 6)
Journal of Medical Ethics     Partially Free   (Followers: 25)
Journal of Medical Ethics and History of Medicine     Open Access   (Followers: 15)
Journal of Medical Humanities     Hybrid Journal   (Followers: 21)
Journal of Medical Hypotheses and Ideas     Open Access  
Journal of Medical Imaging and Health Informatics     Full-text available via subscription   (Followers: 1)
Journal of Medical Investigation and Practice     Open Access  
Journal of Medical Laboratory and Diagnosis     Open Access  
Journal of Medical Law and Ethics     Full-text available via subscription   (Followers: 15)
Journal of Medical Microbiology     Full-text available via subscription   (Followers: 6)
Journal of Medical Sciences     Open Access  
Journal of Medical Sciences     Open Access  
Journal of Medical Screening     Hybrid Journal   (Followers: 6)
Journal of Medical Signals and Sensors     Open Access   (Followers: 3)
Journal of Medical Society     Open Access  
Journal of Medical Systems     Hybrid Journal  
Journal of Medical Toxicology     Hybrid Journal   (Followers: 6)
Journal of Medical Ultrasound     Open Access   (Followers: 2)
Journal of Medicinal Botany     Open Access  
Journal of Medicinal Chemistry     Hybrid Journal   (Followers: 197)
Journal of Medicine     Open Access   (Followers: 1)
Journal of Medicine and Biomedical Research     Open Access   (Followers: 1)
Journal of Medicine and Philosophy     Hybrid Journal   (Followers: 8)
Journal of Medicine and the Person     Hybrid Journal  
Journal of Medicine in Scientific Research     Open Access  
Journal of Medicine in the Tropics     Open Access  
Journal of Medicine Research and Development     Open Access   (Followers: 3)
Journal of Medicine, Physiology and Biophysics     Open Access   (Followers: 5)
Journal of Medicines Development Sciences     Open Access   (Followers: 1)
Journal of Metabolomics & Systems Biology     Open Access  
Journal of Mind and Medical Sciences     Open Access   (Followers: 1)
Journal of Molecular Medicine     Hybrid Journal   (Followers: 11)
Journal of Movement Disorders     Open Access   (Followers: 2)
Journal of Muscle Research and Cell Motility     Hybrid Journal   (Followers: 1)
Journal of Nanotechnology in Engineering and Medicine     Full-text available via subscription   (Followers: 6)
Journal of Natural Medicines     Hybrid Journal  
Journal of Natural Science, Biology and Medicine     Open Access   (Followers: 3)
Journal of Nature and Science of Medicine     Open Access   (Followers: 4)
Journal of Negative and No Positive Results     Open Access  
Journal of Nepalgunj Medical College     Open Access  
Journal of Neurocritical Care     Open Access  
Journal of Neurodegenerative Diseases     Open Access   (Followers: 2)
Journal of Neurorestoratology     Open Access  
Journal of Neuroscience and Neurological Disorders     Open Access  
Journal of Nobel Medical College     Open Access  
Journal of Obesity and Bariatrics     Open Access  
Journal of Occupational Health     Open Access  
Journal of Occupational Therapy Education     Open Access   (Followers: 9)
Journal of Ocular Biology, Diseases, and Informatics     Hybrid Journal  
Journal of Oral Biology and Craniofacial Research     Full-text available via subscription  
Journal of Oral Health and Craniofacial Science     Open Access  
Journal of Orofacial Sciences     Open Access  
Journal of Otorhinolaryngology, Hearing and Balance Medicine     Open Access   (Followers: 1)
Journal of Ovarian Research     Open Access  
Journal of Ozone Therapy     Open Access  
Journal of Palliative Medicine     Hybrid Journal   (Followers: 47)
Journal of Paramedical Sciences & Rehabilitation     Open Access  
Journal of Parkinsonism and Restless Legs Syndrome     Open Access   (Followers: 2)
Journal of Parkinson’s Disease and Alzheimer’s Disease     Open Access  
Journal of Participatory Medicine     Open Access  
Journal of Patan Academy of Health Sciences     Open Access  
Journal of Pathogens     Open Access   (Followers: 1)
Journal of Patient Experience     Open Access  
Journal of Patient Safety and Risk Management     Hybrid Journal   (Followers: 1)
Journal of Patient-Centered Research and Reviews     Open Access  
Journal of Patient-Reported Outcomes     Open Access  
Journal of Periodontal Research     Hybrid Journal  
Journal of Personalized Medicine     Open Access   (Followers: 3)
Journal of Pest Science     Hybrid Journal   (Followers: 1)
Journal of Pharmaceutical Policy and Practice     Open Access   (Followers: 4)
Journal of Physiobiochemical Metabolism     Hybrid Journal   (Followers: 2)
Journal of Physiology-Paris     Hybrid Journal   (Followers: 2)
Journal of Pioneering Medical Sciences     Open Access  
Journal of Postgraduate Medicine     Open Access  
Journal of Pregnancy     Open Access   (Followers: 4)
Journal of Prevention & Intervention Community     Hybrid Journal   (Followers: 6)
Journal of Preventive Medicine and Public Health     Open Access  
Journal of Primary Prevention     Hybrid Journal   (Followers: 7)
Journal of Prosthodontic Research     Full-text available via subscription   (Followers: 1)
Journal of Prosthodontics     Hybrid Journal   (Followers: 2)
Journal of Receptor, Ligand and Channel Research     Open Access  
Journal of Regenerative Medicine     Partially Free   (Followers: 3)
Journal of Research in Medical Sciences     Open Access   (Followers: 2)
Journal of Science and Applications : Biomedicine     Open Access   (Followers: 1)
Journal of Science and Technology (Ghana)     Open Access   (Followers: 3)
Journal of Scientific Innovation in Medicine     Open Access  
Journal of Scientific Perspectives     Open Access   (Followers: 1)
Journal of Sensory Studies     Hybrid Journal   (Followers: 4)
Journal of Shaheed Suhrawardy Medical College     Open Access  
Journal of Shoulder and Elbow Arthroplasty     Open Access  
Journal of Sleep Disorders : Treatment & Care     Hybrid Journal   (Followers: 10)
Journal of South American Earth Sciences     Hybrid Journal   (Followers: 5)
Journal of Spinal Cord Medicine     Hybrid Journal   (Followers: 4)
Journal of Spinal Disorders & Techniques     Hybrid Journal   (Followers: 2)
Journal of Sports Medicine and Allied Health Sciences : Official Journal of the Ohio Athletic Trainers Association     Open Access   (Followers: 1)
Journal of Stem Cell Therapy and Transplantation     Open Access   (Followers: 1)
Journal of Stomal Therapy Australia     Full-text available via subscription  
Journal of Strength and Conditioning Research     Hybrid Journal   (Followers: 73)
Journal of Substance Use     Hybrid Journal   (Followers: 14)
Journal of Surgical Academia     Open Access   (Followers: 1)
Journal of Surgical and Clinical Research     Open Access  
Journal of Surgical Case Reports     Open Access  
Journal of Surgical Education     Full-text available via subscription   (Followers: 3)
Journal of Surgical Technique and Case Report     Open Access  
Journal of Systemic Therapies     Full-text available via subscription   (Followers: 3)
Journal of Taibah University Medical Sciences     Open Access  
Journal of Telemedicine and Telecare     Hybrid Journal   (Followers: 12)
Journal of The Academy of Clinical Microbiologists     Open Access  
Journal of the American Association for Laboratory Animal Science     Full-text available via subscription   (Followers: 7)
Journal of the American College of Certified Wound Specialists     Hybrid Journal   (Followers: 2)
Journal of the American College of Clinical Wound Specialists     Hybrid Journal   (Followers: 2)
Journal of the American Medical Directors Association     Hybrid Journal   (Followers: 6)
Journal of the American Medical Informatics Association : JAMIA     Hybrid Journal   (Followers: 35)
Journal of the American Podiatric Medical Association     Full-text available via subscription   (Followers: 7)
Journal of the Anatomical Society of India     Full-text available via subscription  
Journal of the Anus, Rectum and Colon     Open Access  
Journal of The Arab Society for Medical Research     Open Access  
Journal of the Australasian College of Nutritional and Environmental Medicine     Full-text available via subscription  
Journal of the Australasian Society of Aerospace Medicine     Open Access   (Followers: 1)
Journal of the Ceylon College of Physicians     Open Access  
Journal of the Chinese Medical Association     Open Access   (Followers: 2)
Journal of the College of Community Physicians of Sri Lanka     Open Access  
Journal of The Egyptian Public Health Association     Open Access   (Followers: 1)
Journal of the Formosan Medical Association     Open Access   (Followers: 2)
Journal of the Ghana Science Association     Full-text available via subscription   (Followers: 3)
Journal of the Grodno State Medical University     Open Access   (Followers: 1)
Journal of the History of Medicine and Allied Sciences     Hybrid Journal   (Followers: 17)
Journal of the International Society for Telemedicine and eHealth     Open Access   (Followers: 3)
Journal of the Learning Sciences     Hybrid Journal   (Followers: 17)
Journal of the Medical Library Association     Open Access   (Followers: 284)
Journal of the Medical Sciences (Berkala ilmu Kedokteran)     Open Access   (Followers: 1)
Journal of the National Medical Association     Full-text available via subscription  
Journal of the Peripheral Nervous System     Hybrid Journal   (Followers: 3)
Journal of the Postgraduate Institute of Medicine     Open Access  
Journal of the Renin-Angiotensin-Aldosterone System     Open Access   (Followers: 1)
Journal of the Royal Society of Medicine     Hybrid Journal   (Followers: 2)
Journal of the Ruhunu Clinical Society     Open Access  
Journal of the Scientific Society     Open Access   (Followers: 1)
Journal of the Siena Academy of Sciences     Open Access   (Followers: 1)
Journal of Therapeutic Ultrasound     Open Access  
Journal of Thyroid Research     Open Access   (Followers: 1)

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Journal of the Medical Sciences (Berkala ilmu Kedokteran)
Number of Followers: 1  

  This is an Open Access Journal Open Access journal
ISSN (Print) 0126-1312 - ISSN (Online) 2356-3931
Published by Universitas Gadjah Mada Homepage  [51 journals]
  • CORRELATION BETWEEN CD4 CELL COUNT WITH MUCOCUTANEOUS MANIFESTATIONS:
           STUDY OF PATIENTS WITH HIV IN DR. SARDJITO HOSPITAL, YOGYAKARTA

    • Authors: Nadia Akita Dewi
      Abstract: Introduction:Mucocutaneous disorders often seen in patients with HIV with varying morbidity. HIV progression is characterized by the declining of CD4 cell count and emergence of mucocutaneous manifestations.Objective:To determine the relationship between CD4 cell count with mucocutaneous manifestations in patients with HIV.Method:A cross-sectional study based on medical records at Dr. Sardjito Hospital during the period January 2011-December 2015. We gathered data from medical record such as patient’s age, sex, risk factors of transmission, most mucocutaneous manifestations and CD4 cell count. Cut-off point of CD4 count was 200 cells/mm3.Correlation with clinical manifestations CD4 counts were analyzed using Chi-Square test.Results:Total patients with HIV during the study period was 928 patients; more than half were male(65.4%). Mostly, the patients at a range 20-29 years old(38.69%).The main risk factors for HIV transmission were unsafe sex(75%).The highest CD4 count was 1094 cells/mm3 and the lowest was 1 cell/mm3. We found that there were 306 cases of mucocutaneous manifestations of 928 subjects. Most mucocutaneous manifestations was a fungal infection(40.4%) with the highest infection type was oral candidiasis(33.8%); then non-infection (28%) with the highest type was drug eruption(35.9%); and tumors(0.5%) that was only Kaposi sarcoma cases. We found sexually transmitted infections  (STIs)(18.85%) among the subjects with the highest cases was Condyloma acuminata(49.3%). Statistical analysis showed a significant relationship between CD4 cell count with a fungal infection (P <0.0001; OR 3.8; 95% CI 2.29 to 6.30), viral infection(P =0.0031 OR 0.4 95% CI 0.24-0.74) and parasitic infection(P =0.043 OR 0.2 95% CI 0.06 to 0.61).Conclusion:Alteration in CD4 cell count affect opportunistic infections occurence in patients with HIV.Lower CD4 counts (<200 cells/mm3) increases the risk of fungal infection as much as 3.8 times. Higher CD4 counts (>200 cells/mm3) increase the risk of viral infection by about 2.5 times and parasitic infections as much as 5 times.Keywords: CD4 cell count, mucocutaneous manifestations, HIV 
      PubDate: 2017-10-06
       
  • The effects of duration of mesenteric artery ligation to the ratio of
           TNF-/IL-10 in a rat model of Acute Mesenteric Ischemia (AMI)

    • Authors: Adeodatus Yuda Handaya
      Abstract: ABSTRACTBackground : Acute Mesenteric Ischemia (AMI) has a high mortality rate as a result of the delay in diagnosis in patients. Determination of potent biomarker for early AMI is the key to reducing the high mortality rate associated with AMI. As a proinflammatory cytokine, the level of TNF-α might be affected during the ischemia and reperfusion, with the prediction duration of 60-120 minutes. High level of TNF-α is estimated to stimulate the upregulation of IL-10 as an inhibitor of TNF-α in AMI. This provides a new opportunity for early diagnosis of AMI by measuring the ratio between the two cytokines. The purpose of this study was to investigate the effects of duration of  the mesenteric artery to the ratio of TNF-α/IL-10 in a rat model of AMI.Material and Methods : This was an experimental study using Wistar rat as the animal model. We performed mesenteric artery in 28 male rats to produce a model of AMI, with ligation duration of 0, 30, 60, 90, 120, 150, and 180 minutes. At the end of ligation of each group, blood samples were taken for examination of TNF-α and IL-10 using ELISA. As for the microscopic examination of tissue necrosis, intestinal organ samples were taken and made into paraffin blocks and stained using Haematoxylin-Eosin.Results : TNF-α was found increased in minute 120 compared to other treatment groups (p<0.05). IL-10 was found to be increased in minute 180 compared to control group (p<0.05). Microscopic examination showed that the duration of ligation affects the structure and morphology of intestinal mucosa characterized by discoloration of organs along with increasing the ligation duration.Conclusion : Ligation of the superior mesenteric artery was found to be significantly increased the expression TNF-α and offset by increased expression of IL-10. Besides, we expected the protective effect of IL-10 as a biomarker candidate of AMI. This can be seen at least in 180 minutes after an elevated level of TNF-α in ischemia duration of 120 minutes. ABSTRAK            Iskemik Mesenterik Akut (IMA) memiliki angka mortalitas yang tinggi akibat lambatnya diagnosis awal pasien. Penentuan biomarker poten yang terlibat pada awal proses IMA menjadi target di klinik. Kadar TNF-α sebagai sitokin prediktor poten di awal kasus dengan durasi prediksi berkisar 60-120 menit. Tingginya kadar TNF-α diestimasi akan menstimulasi peningkatan regulasi IL-10 sebagai inhibitor TNF-α  pada kasus AMI. Hal ini memberikan peluang baru diagnostik awal kejadian IMA dengan mengetahui rasio diantara kedua sitokin tersebut di area iskemia intestinal. Tujuan dari penelitian ini adalah untuk mengetahui pengaruh durasi ligasi arteri mesenterika superior dengan rasio TNF-α/IL-10 pada tikus model IMA. Pada 28 ekor tikus Wistar jantan dilakukan ligasi arteri mesenterika superior untuk menghasilkan suatu model IMA dengan durasi ligasi 0, 30, 60, 90, 120, 150, dan 180 menit. Pada akhir waktu dari masing-masing kelompok dilakukan pengambilan sampel darah untuk pemeriksaan kadar TNF-α  dan IL-10 secara imunologis dengan metode ELISA. Sedangkan untuk pemeriksaan mikroskopik nekrosis jaringan sampel oran intestinal diambil dan dibuat dalam paraffin blok dan dicat dengan Hematoxylin-Eosin. Didapatkan perbedaan yang secara statistik bermakna pada kenaikan kadar TNF-α pada menit ke-120 dibandingkan kelompok perlakuan lainnya (p<0,05). Didapatkan peningkatan bermakna kadar IL-10 pada kelompok perlakuan ligasi 180 menit dibandingkan kelompok kontrol (p<0,05). Hasil pemeriksaan mikroskopik menunjukkan bahwa lama ligasi mempengaruhi struktur morfologi mukosa. Efek ligasi arteri mesenterika superior mampu meningkatkan ekspresi TNF-α secara signifikan dan diimbangi dengan peningkatan ekspresi IL-10 pada tikus model iskemia mesenterika akut. Disamping itu muncul dugaan awal efek protektif IL-10 sebagai kandidat prediktor AMI dapat diketahui minimal pada rentang durasi 180 menit pasca peningkatan kadar TNF-α di durasi iskemia 120 menit. Keywords: Acute Mesenteric Ischemia – Mesenteric artery - TNF-α/IL-10 ratio
      PubDate: 2017-10-06
       
  • Comparison of Bcl-xL protein expression in placental trophoblast cells
           between pregnancy complicated by severe preeclampsia and normotensive
           pregnancy

    • Authors: Diah Rumekti Hadiati, Arsi Palupi, Mohammad Hakimi, Sofia Mubarika Haryana
      Abstract: Background: Preeclampsia is one of the main causes of maternal and perinatal mortality and morbidity. The pathogenesis of preeclampsia remains unclear but it is believed that the failure of spiral arteries remodeling will eventually leads to placental hypoxia. In pregnancy complicated by preeclampsia, trophoblast apoptosis is considered to be excessive. Although this hypothesis is still under study, it is believed that regulation of apoptosis in trophoblast cells plays a key role in the pathophysiology of preeclampsia. The mechanism of molecular apoptosis in human is very complicated and involves many signaling molecules, one of them is Bcl-2 protein. Bcl-2 protein group consists of proapoptosis (Bax) protein and apoptosis inhibitor (Bcl-2 and Bcl-xL) protein.Objective: To compare the expression of Bcl-xL protein in placental trophoblast cells between pregnancy complicated by severe preeclampsia and normotensive pregnancy.Methods: The design of this study was cross sectional design. The population were patients with severe preeclampsia and normotensive patients which were treated in Dr. Sardjito Hospital, Yogyakarta, Indonesia from October 2011 until March 2012. Placenta samples were obtained from 43 patients with pregnancy complicated by severe preeclampsia and 38 patients with normotensive pregnancy. Bcl-xL protein expression was observed using immunohistochemistry technique. Statistical analysis was conducted using independent t-test (p<0.05), bivariate analysis using chi-square test, and multivariate analysis using logistic regression.Results: There was significant difference in Bcl-xL protein expression in trophoblast cells between pregnancy complicated by severe preeclamptic group (1,29 ± 0,12) compared to normotensive group (1,71 ± 0,14) with p=0.00. Multivariate analysis using logistic regression showed that diagnosis of severe preeclampsia had a statistically significant role in Bcl-xL protein expression with p= 0.000.Conclusion: Expression of Bcl-xL protein is lower in pregnancy complicated by severe preeclampsia compared to normotensive pregnancy.
      PubDate: 2017-06-21
       
  • Cinnamomum burmannii improves insulin serum level in the normal obese
           subjects : preliminary study

    • Authors: Flori R. Sari, Hari Hendarto, Chris Adhyanto
      Abstract: ABSTRACTObesity is characterized with excessive accumulation of the body fat which occurs when the energy intake exceeds the expenditure. It is routinely associated with insulin resistance and hyperinsulinemia. Additionally, suppressing insulin level protects female mice from weight gaining. Cinnamon suppresses hyperinsulinemia condition in the type 2 diabetic rat suggesting the possible beneficial role of cinnamon in the obesity. We aimed to investigate the role of cinnamon in the normal obese subjects. In this preliminary cross-over clinical trial, 24 normal obese subjects were recruited and divided randomly into two groups, treatment and placebo. Two grams of Cinnamomum burmannii extract were given twice daily for 56 days in the treatment group. Normal obese subjects given placebo were allocated as the placebo group. After finishing the treatment, each of the group ran a one month run-in period, then the groups were cross-overed for the next 56 days. Body Mass Index (BMI), insulin serum level, cholesterol and triglyceride plasma level were measured at the beginning and at the end of the study. No diet restriction nor exercise intervention was given during the study. At the end of the study, BMI in the treatment group were slightly reduced when compared to the placebo group (58% vs. 33%), however, the results did not reach significancies in the statistical level. Moreover, significant reduction in the insulin serum level was observed in 63% subject in the treatment group compared to 33% subject in the placebo group (p < 0.05). Additionally, there were no significant differences of cholesterol and triglyceride plasma level observed in the both group.Conclusion. Cinnamon extract may give beneficial role in the normal obese subjects by suppressing the serum insulin level. Further studies are required to elucidate the specific role of cinnamon in preventing weight gain.Keywords: Cinnamomum burmannii, obesity, insulin, body mass index lipid profile
      PubDate: 2017-03-03
       
  • Comparing P-Selectin (CD62P) expression in patients receiving
           non-leukodepleted vs leukodepleted thrombocyte concentrates

    • Authors: Teguh Triyono
      Abstract: Thrombocyte concentrate (TC) transfusion is an important supportive therapy in patients with thrombocytopenia. The risks in platelet transfusions may be related to the content of TC including the contaminant leukocytes. The aim of this study was to assess the risk of increased level of P-Selectin (CD62P) expression of non-leukodepleted TC transfusions.This was a quasi-experimental study. Subjects were children patients aged 1-18 years who received a non-leukodepleted or a leukodepleted TC transfusions. Comparison of the proportion of  increased expression of CD62P in both groups expressed as relative risk. The subjects consisted of 51 patients who received non-leukodepleted and 52 patients who received leukodepleted TC transfusions. The risk of increased expression of CD62P in patients receiving non-leukodepleted TC transfusions were 2.38 (95%CI:1.60-3.53) times higher than those who received leukodepleted TC. Non-leukodepleted have significant higher risks of increased CD62P expression than leukodepleted  TC transfusions.
      PubDate: 2017-03-03
       
 
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