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  Subjects -> MEDICAL SCIENCES (Total: 7249 journals)
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MEDICAL SCIENCES (1802 journals)                  1 2 3 4 5 6 7 8 | Last

Showing 1 - 200 of 3562 Journals sorted alphabetically
16 de Abril     Open Access  
AADE in Practice     Hybrid Journal   (Followers: 4)
ABCS Health Sciences     Open Access   (Followers: 1)
Abia State University Medical Students' Association Journal     Full-text available via subscription  
ACIMED     Open Access   (Followers: 1)
ACS Medicinal Chemistry Letters     Full-text available via subscription   (Followers: 39)
Acta Bio Medica     Full-text available via subscription   (Followers: 2)
Acta Bioethica     Open Access   (Followers: 1)
Acta Bioquimica Clinica Latinoamericana     Open Access   (Followers: 1)
Acta Facultatis Medicae Naissensis     Open Access  
Acta Informatica Medica     Open Access   (Followers: 1)
Acta Medica Bulgarica     Open Access  
Acta Medica Colombiana     Open Access   (Followers: 1)
Acta Médica Costarricense     Open Access   (Followers: 2)
Acta Medica Indonesiana     Open Access  
Acta medica Lituanica     Open Access  
Acta Medica Marisiensis     Open Access  
Acta Medica Martiniana     Open Access  
Acta Medica Nagasakiensia     Open Access  
Acta Medica Peruana     Open Access   (Followers: 2)
Acta Médica Portuguesa     Open Access  
Acta Medica Saliniana     Open Access  
Acta Scientiarum. Health Sciences     Open Access  
Acupuncture & Electro-Therapeutics Research     Full-text available via subscription   (Followers: 2)
Addiction Science & Clinical Practice     Open Access   (Followers: 7)
Addictive Behaviors Reports     Open Access   (Followers: 6)
Advanced Health Care Technologies     Open Access   (Followers: 4)
Advanced Science, Engineering and Medicine     Partially Free   (Followers: 7)
Advances in Bioscience and Clinical Medicine     Open Access   (Followers: 5)
Advances in Clinical Chemistry     Full-text available via subscription   (Followers: 29)
Advances in Life Course Research     Hybrid Journal   (Followers: 8)
Advances in Lipobiology     Full-text available via subscription   (Followers: 2)
Advances in Medical Education and Practice     Open Access   (Followers: 26)
Advances in Medical Sciences     Hybrid Journal   (Followers: 6)
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Advances in Medicine     Open Access   (Followers: 2)
Advances in Microbial Physiology     Full-text available via subscription   (Followers: 4)
Advances in Molecular Oncology     Open Access   (Followers: 1)
Advances in Molecular Toxicology     Full-text available via subscription   (Followers: 8)
Advances in Parkinson's Disease     Open Access  
Advances in Phytomedicine     Full-text available via subscription  
Advances in Preventive Medicine     Open Access   (Followers: 6)
Advances in Protein Chemistry and Structural Biology     Full-text available via subscription   (Followers: 20)
Advances in Therapy     Hybrid Journal   (Followers: 5)
Advances in Veterinary Science and Comparative Medicine     Full-text available via subscription   (Followers: 13)
Advances in Virus Research     Full-text available via subscription   (Followers: 5)
Advances in Wound Care     Hybrid Journal   (Followers: 10)
African Health Sciences     Open Access   (Followers: 2)
African Journal of Biomedical Research     Open Access  
African Journal of Clinical and Experimental Microbiology     Open Access   (Followers: 1)
African Journal of Laboratory Medicine     Open Access   (Followers: 2)
African Journal of Medical and Health Sciences     Open Access   (Followers: 2)
African Journal of Trauma     Open Access  
Afrimedic Journal     Open Access   (Followers: 2)
Aggiornamenti CIO     Hybrid Journal   (Followers: 1)
AIDS Research and Human Retroviruses     Hybrid Journal   (Followers: 8)
AJOB Primary Research     Partially Free   (Followers: 3)
Aktuelle Ernährungsmedizin     Hybrid Journal   (Followers: 4)
Al-Azhar Assiut Medical Journal     Open Access  
Alexandria Journal of Medicine     Open Access   (Followers: 1)
Allgemeine Homöopathische Zeitung     Hybrid Journal   (Followers: 2)
Alpha Omegan     Full-text available via subscription  
ALTEX : Alternatives to Animal Experimentation     Open Access   (Followers: 3)
American Journal of Biomedical Engineering     Open Access   (Followers: 11)
American Journal of Biomedical Research     Open Access   (Followers: 2)
American Journal of Biomedicine     Full-text available via subscription   (Followers: 6)
American Journal of Chinese Medicine, The     Hybrid Journal   (Followers: 5)
American Journal of Clinical Medicine Research     Open Access   (Followers: 5)
American Journal of Family Therapy     Hybrid Journal   (Followers: 11)
American Journal of Law & Medicine     Full-text available via subscription   (Followers: 12)
American Journal of Lifestyle Medicine     Hybrid Journal   (Followers: 5)
American Journal of Managed Care     Full-text available via subscription   (Followers: 11)
American Journal of Medical Case Reports     Open Access   (Followers: 1)
American Journal of Medical Sciences and Medicine     Open Access   (Followers: 1)
American Journal of Medicine     Hybrid Journal   (Followers: 46)
American Journal of Medicine and Medical Sciences     Open Access   (Followers: 1)
American Journal of Medicine Studies     Open Access  
American Journal of Medicine Supplements     Full-text available via subscription   (Followers: 3)
American Journal of the Medical Sciences     Hybrid Journal   (Followers: 12)
American Journal on Addictions     Hybrid Journal   (Followers: 9)
American Medical Journal     Open Access   (Followers: 4)
American medical news     Free   (Followers: 3)
American Medical Writers Association Journal     Full-text available via subscription   (Followers: 2)
Amyloid: The Journal of Protein Folding Disorders     Hybrid Journal   (Followers: 4)
Anales de la Facultad de Medicina     Open Access  
Anales de la Facultad de Medicina, Universidad de la República, Uruguay     Open Access  
Anales del Sistema Sanitario de Navarra     Open Access   (Followers: 1)
Analgesia & Resuscitation : Current Research     Hybrid Journal   (Followers: 3)
Anatomical Science International     Hybrid Journal   (Followers: 2)
Anatomical Sciences Education     Hybrid Journal   (Followers: 1)
Anatomy Research International     Open Access   (Followers: 2)
Angewandte Schmerztherapie und Palliativmedizin     Hybrid Journal  
Angiogenesis     Hybrid Journal   (Followers: 3)
Annales de Pathologie     Full-text available via subscription  
Annales françaises d'Oto-rhino-laryngologie et de Pathologie Cervico-faciale     Full-text available via subscription   (Followers: 3)
Annals of African Medicine     Open Access   (Followers: 1)
Annals of Anatomy - Anatomischer Anzeiger     Hybrid Journal   (Followers: 2)
Annals of Bioanthropology     Open Access   (Followers: 3)
Annals of Biomedical Engineering     Hybrid Journal   (Followers: 18)
Annals of Biomedical Sciences     Full-text available via subscription   (Followers: 3)
Annals of Clinical Microbiology and Antimicrobials     Open Access   (Followers: 8)
Annals of Family Medicine     Open Access   (Followers: 13)
Annals of Fundeni Hospital     Open Access   (Followers: 1)
Annals of Ibadan Postgraduate Medicine     Open Access  
Annals of Medical and Health Sciences Research     Open Access   (Followers: 7)
Annals of Medicine     Hybrid Journal   (Followers: 12)
Annals of Medicine and Surgery     Open Access   (Followers: 5)
Annals of Microbiology     Hybrid Journal   (Followers: 10)
Annals of Nigerian Medicine     Open Access   (Followers: 1)
Annals of Saudi Medicine     Open Access  
Annals of the New York Academy of Sciences     Hybrid Journal   (Followers: 5)
Annals of The Royal College of Surgeons of England     Full-text available via subscription   (Followers: 3)
Annual Reports in Medicinal Chemistry     Full-text available via subscription   (Followers: 7)
Annual Reports on NMR Spectroscopy     Full-text available via subscription   (Followers: 4)
Annual Review of Medicine     Full-text available via subscription   (Followers: 18)
Anthropological Review     Open Access   (Followers: 24)
Anthropologie et santé     Open Access   (Followers: 5)
Antibiotics     Open Access   (Followers: 9)
Antibodies     Open Access   (Followers: 2)
Antibody Technology Journal     Open Access   (Followers: 1)
Anuradhapura Medical Journal     Open Access  
Anwer Khan Modern Medical College Journal     Open Access   (Followers: 2)
Apmis     Hybrid Journal   (Followers: 1)
Apparence(s)     Open Access   (Followers: 1)
Applied Clinical Informatics     Hybrid Journal   (Followers: 2)
Applied Medical Informatics     Open Access   (Followers: 11)
Arab Journal of Nephrology and Transplantation     Open Access   (Followers: 1)
Arak Medical University Journal     Open Access  
Archive of Clinical Medicine     Open Access   (Followers: 1)
Archive of Community Health     Open Access  
Archives of Biomedical Sciences     Open Access   (Followers: 7)
Archives of Medical and Biomedical Research     Open Access   (Followers: 3)
Archives of Medical Laboratory Sciences     Open Access   (Followers: 1)
Archives of Medicine and Health Sciences     Open Access   (Followers: 3)
Archives of Trauma Research     Open Access   (Followers: 2)
Archivos de Medicina (Manizales)     Open Access  
ArgoSpine News & Journal     Hybrid Journal  
Arquivos Brasileiros de Oftalmologia     Open Access  
Arquivos de Ciências da Saúde     Open Access  
Arquivos de Medicina     Open Access  
ARS Medica Tomitana     Open Access   (Followers: 1)
Art Therapy: Journal of the American Art Therapy Association     Full-text available via subscription   (Followers: 10)
Arterial Hypertension     Open Access  
Artificial Intelligence in Medicine     Hybrid Journal   (Followers: 12)
Artificial Organs     Hybrid Journal   (Followers: 1)
Asia Pacific Family Medicine     Open Access  
Asia Pacific Journal of Clinical Nutrition     Full-text available via subscription   (Followers: 9)
Asia Pacific Journal of Clinical Trials : Nervous System Diseases     Open Access  
Asian Bioethics Review     Full-text available via subscription   (Followers: 2)
Asian Journal of Cell Biology     Open Access   (Followers: 6)
Asian Journal of Health     Open Access   (Followers: 3)
Asian Journal of Medical and Biological Research     Open Access   (Followers: 2)
Asian Journal of Medical and Pharmaceutical Researches     Open Access   (Followers: 1)
Asian Journal of Medical Sciences     Open Access   (Followers: 1)
Asian Journal of Scientific Research     Open Access   (Followers: 2)
Asian Journal of Transfusion Science     Open Access   (Followers: 2)
Asian Medicine     Hybrid Journal   (Followers: 4)
ASPIRATOR : Journal of Vector-borne Disease Studies     Open Access  
Astrocyte     Open Access  
Atención Familiar     Open Access  
Atención Primaria     Open Access   (Followers: 1)
Audiology - Communication Research     Open Access   (Followers: 8)
Auris Nasus Larynx     Full-text available via subscription  
Australian Coeliac     Full-text available via subscription   (Followers: 2)
Australian Family Physician     Full-text available via subscription   (Followers: 3)
Australian Journal of Medical Science     Full-text available via subscription   (Followers: 1)
Autopsy and Case Reports     Open Access  
Aviation, Space, and Environmental Medicine     Full-text available via subscription   (Followers: 10)
Avicenna     Open Access   (Followers: 2)
Avicenna Journal of Medicine     Open Access   (Followers: 1)
Bangabandhu Sheikh Mujib Medical University Journal     Open Access   (Followers: 1)
Bangladesh Journal of Anatomy     Open Access   (Followers: 1)
Bangladesh Journal of Bioethics     Open Access  
Bangladesh Journal of Medical Biochemistry     Open Access   (Followers: 3)
Bangladesh Journal of Medical Education     Open Access   (Followers: 2)
Bangladesh Journal of Medical Microbiology     Open Access   (Followers: 3)
Bangladesh Journal of Medical Physics     Open Access  
Bangladesh Journal of Medical Science     Open Access  
Bangladesh Journal of Medicine     Open Access   (Followers: 1)
Bangladesh Journal of Physiology and Pharmacology     Open Access  
Bangladesh Journal of Scientific Research     Open Access   (Followers: 2)
Bangladesh Medical Journal     Open Access  
Bangladesh Medical Journal Khulna     Open Access  
Bangladesh Medical Research Council Bulletin     Open Access  
Basal Ganglia     Hybrid Journal  
Basic Sciences of Medicine     Open Access   (Followers: 2)
BBA Clinical     Open Access  
BC Medical Journal     Free  
Benha Medical Journal     Open Access  
Bijblijven     Hybrid Journal  
Bijzijn     Hybrid Journal   (Followers: 2)
Bijzijn XL     Hybrid Journal   (Followers: 1)
Bio-Algorithms and Med-Systems     Hybrid Journal   (Followers: 1)
BioDiscovery     Open Access   (Followers: 2)
Bioelectromagnetics     Hybrid Journal   (Followers: 1)
Bioengineering & Translational Medicine     Open Access  
Bioethics     Hybrid Journal   (Followers: 14)
Bioethics Research Notes     Full-text available via subscription   (Followers: 14)
Biologics in Therapy     Open Access  
Biology of Sex Differences     Open Access   (Followers: 3)

        1 2 3 4 5 6 7 8 | Last

Journal Cover African Journal of Biomedical Research
  [SJR: 0.133]   [H-I: 11]   [0 followers]  Follow
    
  This is an Open Access Journal Open Access journal
   ISSN (Print) 1119-5096
   Published by African Journals Online Homepage  [266 journals]
  • Hypolipidemic effects of Olax subscorpioidea Oliv. root extract in
           experimental rat model

    • Authors: I.T. Gbadamosi, L.A. Raji, A.A. Oyagbemi, T.O. Omobowale
      Abstract: Olax subscorpioidea (Olacaceae) is a major component of a recipe used traditionally in the management of Obesity. In view of the traditional therapeutic use of the plant, this research screened the ethanol root extract of the plant for hypolipidemic effect in Wistar rats. This was carried out to validate its potential as a lipid lowering agent. The experimental rats were randomly distributed into five groups of 7 animals each. Group 1 (not induced with hyperlipidemia) received distilled water; Group 2 (induced with hyperlipidemia). Group 3 (induced) received 10 mg/kg bw of atorvastatin. Groups 4 and 5 were induced with hyperlipidemia and treated with 200 and 400 mg/kg bw extract of Olax subscorpioidea respectively for 14 days. Olax subscorpioidea root contained saponins (865.00 mg/100 g), alkaloids (963.33 mg/100 g), tannins (863.33 mg/100 g), flavonoids (636.67 mg/100 g), anthraquinones (46.67 mg/100 g) and proanthocyanidins (2.67 mg/g). The extract gave 47.30% inhibition against DPPH+. Significant decrease in TC, TG and LDL was recorded in treated groups with 200 and 400 mg/kg bw of the extract. There was also a significant increase in HDL level of treated groups when compared with induced group. This result suggests that ethanol extract of Olax subscorpioidea at 200 and 400 mg/kg bw possesses hypolipidemic effects on diet induced hyperlipidemic rats. The observed bioactivity could be attributed to phytochemical components, proximate contents as well as antioxidant activity of the plant.Keywords: Olax subscorpioidea, Phytochemicals, Nutrients, Antioxidant, Lipid profile, Biochemicals, Histopathology.
      PubDate: 2017-12-06
      Issue No: Vol. 20, No. 3 (2017)
       
  • Unripe Musa paradisiacal fruit diet ameliorates impaired glucose
           regulation caused by Iron-induced oxidative stress

    • Authors: A.O. Ige, A.O. Oyekunle, M.O. Olaoye, E.O. Adewoye
      Abstract: Excess iron impairs glucose regulatory mechanisms through an increase in  oxidative stress. Unripe Musa paradisiaca fruit (UMP) diets have been reported to alleviate diabetes and exert antioxidant effects. In this study, some glucose  regulatory indices were investigated in Wistar rats with iron-induced oxidative  stress and maintained on UMP-diet. Thirty-rats were divided into five equal groups. Group 1 (control) received standard rat chow only. Oxidative stress was induced  with ferrous-sulphate (3mg/kg, i.p.) in groups 2–5 and animals were simultaneously maintained on standard rat chow (group2), 20%UMP-diet (group3), 40%UMP-diet (group4) and 80%UMP-diet (group5) respectively, for 28days. Phytochemical,  mineral and proximate analysis of UMP were evaluated. Blood glucose was  monitored on days 0,7,14,21 and 28 respectively using the tail tipping method. At  day28 post-treatment, blood samples were obtained from each animal; serum was extracted and assayed for iron, total iron binding capacity (TIBC), insulin and interleukin-6 levels. Muscle glycogen was determined using the anthrone method;  insulin resistance, pancreatic beta cell function and transferrin saturation levels were mathematically calculated. Pancreatic samples were histologically evaluated using H and E stains. Phytochemical screening showed the presence of flavonoids, saponins, phenols, tannins, coumarins, steroids and alkaloid. Mineral and proximate analysis indicate the presence of proteins, fibre, sodium, iron, zinc and potassium. Blood glucose on day28 was unchanged in control, increased in group2 and decreased in groups 3-5 respectively compared to day 0. Beta cell function, insulin and TIBC were decreased while transferrin saturation was increased in group2 compared to all other groups. Serum iron and interleukin-6 was increased while muscle glycogen was reduced in group2 compared to groups4 and 5 respectively. Group2 animals had pancreas with necrotic acinar cells and ill-defined islet of Langerhans. These pathologies were not observed in normal and UMP treatment groups. This study suggests that unripe Musa paradisiaca fruit diet may reduce the deleterious effects of iron-induced oxidative stress on glucose regulatory indices.
      Keywords: Unripe Musa paradisiaca, glucose, iron, iron-induced oxidative stress
      PubDate: 2017-12-06
      Issue No: Vol. 20, No. 3 (2017)
       
  • Brachystegia eurycoma harms (Fabaceae) stem bark extract modulates
           gastrointestinal motility in animal models

    • Authors: E.E. Bafor, O. Chiekwe, J. Ofeimun, F. Amaechina, B. Ayinde
      Abstract: Brachystegia eurycoma, a plant in the Fabaceae family has been used ethno- medicinally in the softening of bulky stool, and has been associated with protection  of colonic cancer. This study was therefore aimed at the evaluation of possible  modulatory effect of the stem bark extract of Brachystegia eurycoma (BE) on  gastrointestinal motility. The in vivo activity of BE on gastrointestinal motility was  evaluated using the following experimental models viz: normal intestinal transit,  castor oil- induced diarrhoea, and intestinal fluid accumulation tests in rodents. The in vitro activity on isolated intestinal motility was also investigated on the following parameters viz: spontaneous, acetylcholine- and high KCl-induced intestinal  contractions. BE (100, 300 and 700 mg/kg p.o.) produced a moderate decrease in  normal intestinal transit while significantly (P < 0.05) reducing the propulsive  movement in castor oil-induced diarrhoea compared with the control group (5% tween 80 10 ml/kg, p.o.). The extract also produced a dose-dependent, significant  increase in the onset of diarrhoea. BE (100, 300 and 700 mg/kg) additionally  reduced the diarrhoea score, number and weight of wet stools. The in-vivo  antidiarrheal index (ADIin-vivo) of 37.14% produced by the extract at the dose of  300 mg/kg was lower compared to that produced by loperamide 5 mg/kg (54.74%). In vitro results revealed that the crude extract, the aqueous and chloroform  fractions inhibited both spontaneous, acetylcholine and KCl-induced contractions in a concentration-dependent manner. In conclusion, the stem bark extract of  Brachystegia eurycoma has been shown to exhibit antidiarrheal activity, possibly mediated by anti-muscarinic receptor activity or interaction with calcium channels
      Keywords: Antidiarrhea; Gastrointestinal motility; Brachystegia eurycoma;  Diarrhea; Enteropooling
      PubDate: 2017-12-06
      Issue No: Vol. 20, No. 3 (2017)
       
  • Antioxidant activity, total phenolic and flavonoid contents of the
           methanol whole plant extract of Elytraria marginata (Vahl)

    • Authors: C. Ogbiko, M.U. Dabai, M. Amanabo, E.V.C. Okoh, B.H. Bature
      Abstract: Elytraria marginata (Vahl) isused in Nigeria folk medicine as febrifuges, pulmonary problems and cancer related ailments. This study evaluated scientifically the phytochemical screening, antioxidant, total phenolic and flavonoids contents of the whole plant extract with a view to validate its folkloric usage. The phytochemical constituents were ascertained using standard procedures. In vitroantioxidant properties of methanol whole plant extract (MWPE) were evaluated using the free radical scavenging activities by 1, 1-diphenyl-2-picryl-hydrazyl (DPPH), nitroblue tetrazolium (NBT) and ferric reducing assays with ascorbic acid as control. Total phenol and flavonoid contents of the various extracts were determined using gallic acid and quercetin as positive controls. Phytochemical analysis of MWPE showed presence of major classes of phytochemicals. In vitro antioxidant activities of the crude extracts were significant and comparable with the standard ascorbic acid.The high contents of total phenolic compounds (244.14 ± 1.62 mg GAE/g of dry extract) and total flavonoids (66.24 ± 2.22 mg QE/g of dry extract) indicated that these compounds contribute to the antioxidative activity. The present study, hence validates that the MWPE of Elytraria marginata might have good potential as a source for natural health products due to its antioxidant activities.
      Keywords: Elytraria marginata, antioxidant activity, polyphenol compounds, flavonoids
      PubDate: 2017-12-06
      Issue No: Vol. 20, No. 3 (2017)
       
  • Effects of diets containing unripe plantain diet on brain serotonin in
           mice

    • Authors: P. Erigbali, K. Kiridi, I. Ogregade
      Abstract: Musa paradisiaca (Plantain) fruit has been shown to be useful for nutritional, medicinal and industrial purposes. It contains serotonin (5-HT) and its immediate precursor, 5-Hydroxytryptophan (5-HTP). Serotonin plays a fundamental role in integration of behaviour and many physiological functions including regulation of mood, anxiety, arousal, aggression, impulse control, and thinking abilities. In this study, the effect of plantain-containing mouse diet on brain serotonin mice was investigated in mice. Thirty adult Swiss mice were divided into three groups of ten each and fed normal rodent chow containing 0%, 50% and 100% unripe plantain. After thirty days, the brain levels of 5-HT and 5-HTP were measured using High Performance Liquid Chromatography (HPLC) technique. Results show that 5-HT level was significantly increased in the plantain-diet fed mice. Conversely, 5-HTP level was reduced in the 100% plantain fed mice when compared with the control.
      Keywords: Musa paradisiaca, Unripe plantain, serotonin, 5-Hydroxytryptophan
      PubDate: 2017-12-06
      Issue No: Vol. 20, No. 3 (2017)
       
  • Erratum: Protective effects of aqueous extract of Telfairia occidentalis
           on mercury-induced histological and oxidative changes in the Rat
           hippocampus and cerebellum

    • Authors: O. Owoeye, M.O. Gabriel
      Abstract: Erratum: Protective effects of aqueous extract of Telfairia occidentalis on mercury-induced histological and oxidative changes in the Rat hippocampus and cerebellum. Afr. J. Biomed. Res. 2016: 19(3):241-243
      PubDate: 2017-12-06
      Issue No: Vol. 20, No. 3 (2017)
       
  • Barriers to utilization of cervical cancer screening services among women
           of reproductive age in Ondo, southwest Nigeria

    • Authors: M.A. Titiloye, Y.T. Womitenren, O.S. Arulogun
      Abstract: Cervical cancer (CC) is the second most commonly diagnosed cancer among women of reproductive age group; yet screening for early detection of the disease among  them is not a common practice in Nigeria. This study therefore, investigated the  barriers to utilization of cervical cancer screening service among women of  reproductive age in Ondo town, Ondo State. A descriptive cross-sectional survey  was adopted using a four-stage sampling technique to select 244 consenting women of reproductive age in Ondo town. A validated interviewer administered  questionnaire was used to solicit information on CC-related knowledge and  perception, utilization and barriers to utilization of the screening services. Data were  analyzed using descriptive statistics and Chi-square test at p<0.05.  Respondents’ mean age was 30±6.8 years, 70.9% were married and 58.2% had  tertiary education. Majority (73.8%) had heard about CC and 67.8% correctly  defined CC. Mean knowledge score was 17.1±5.3. Respondents with poor, fair and good knowledge of CC were 11.1%, 53.3%, and 35.6% respectively. Positive  perception towards CC was reported by 42.6% of respondents. Only (15.6%) of the respondents have done screening for CC and the decision to do the screening was personal in 78.6% of the respondents. Main barriers hindering the utilization of CC screening services were: fear of the result (65.1%), negative attitudes of health  worker (51.3%) and husband’s influence on decision (51.0%). CC knowledge of  respondents was not significantly associated with utilization of cervical screening  service (X2 =3.117 P>0.05). Low utilization of the screening services based on  perceived misconception was noticed among study participants. Health promotion strategies that will target women and their spouse are therefore recommended. Health workers should help change perception of non-susceptibility of the women
      Keywords: Cervical cancer, knowledge, perception, barriers to utilization of the screening service
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Perception, acceptance and uptake of Human papillomavirus vaccine among
           female adolescents in selected secondary schools in Ibadan, Nigeria

    • Authors: C.M. Ndikom, P.I. Oboh
      Abstract: Infection with Human papillomavirus (HPV) contributes to malignant changes in the cervix leading to cancer mortality among women. HPV vaccine is now available for its prevention, yet the level of uptake is low. The study aimed at determining  Perception, Acceptance and Uptake of Human papillomavirus Vaccine among female  adolescents in selected secondary schools in Ibadan, Nigeria. This cross-sectional study was conducted among 296 female adolescent senior secondary  school students in Ibadan, Nigeria. Respondents were selected using purposive  sampling method and data were collected using self-administered questionnaire.  The data were analysed using the Statistical Package for Social Sciences version 20.0. Variables were presented as frequency tables and hypotheses were tested  using chi-square and Fisher’s exact test at P≤ 0.05. Most 142(48.0%) of the  respondents were between ages 15-17. The respondents’ perception and knowledge about HPV vaccine, HPV infection and cervical cancer was generally poor.  Furthermore, only 12(4.1%) of the respondents have received the HPV vaccine  before the study. There is a significant association between adolescent’s perception  and uptake of HPV vaccine p=0.000 as well as Perception and readiness for the  use  of HPV vaccine (p=0.007). Parental approval and readiness for HPV vaccine uptake were found to be significantly associated (p =0.000). Since knowledge about Human Papilloma Virus Vaccination is quite low, there is need to increase  awareness about the Vaccination among female adolescents and their mothers. Also, peer educators in schools can be trained to improve awareness in schools so as to reduce the incidence of cervical cancer.Keywords: Perception, Acceptance, Use, Human Papilloma Vaccine, Female   Adolescent
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Prevalence of malaria parasitaemia among children resident in orphanages
           in Anambra state, Nigeria

    • Authors: B.O. Oluboyo, I.B. Enweani, I.M. Ekejindu, A.O. Oluboyo
      Abstract: Malaria parasitemia in Anambra State and in Nigeria at large is of public health  significance. Determination of malaria parasite density is helpful in disease  monitoring and assessment of drug efficacy. This study investigated the prevalence of malaria parasitemia among children resident in orphanages located in Anambra  State, Nigeria and related the malaria parasite density gotten from actual WBC  count with value got using World Health Organization (WHO) assumed mean. A total of 272 subjects comprising 172 orphans and 100 children in family setting  (controls) were investigated for malaria parasitemia using Giemsa stain. Malaria  parasite density was carried out according to WHO recommendation. A prevalence  of 23.3% and 12.0% malaria parasitemia were observed for children in orphanage  and family setting respectively (p<0.05). The disease significantly affected the  children in all the age ranges with children in ages 0-5 most affected (p<0.05). The  mean malaria parasite density measured based on WHO assumed WBC mean value  was significantly higher than using the actual WBC count (p˂0.05). The use of total  WBC count reference value for a given locality in measuring malaria parasite density is recommended rather than an assumed value.
      Keywords: Prevalence, Malaria Parasitaemia, Orphanage, Parasite Density
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Issues and challenges of implementing mobile e-Healthcare systems in South
           Africa

    • Authors: A.I. Ilorah, N. Sello, S.N Mokwena, G.E.M Ditsa
      Abstract: Mobile e-Healthcare implementation in South Africa has the potential to improve the delivery and access to healthcare services. However implementation of Mobile  e-Healthcare continues to face various challenges such as inadequate policy, lack of management support, poor infrastructure and concerns around security of  information, especially in the rural and remote areas. This study aims at identifying the issues and challenges of implementing Mobile e-Healthcare in South Africa and then develop a framework which healthcare facilities can use as a guide for  successful implementation of a Mobile e-Healthcare system. An exploratory study was conducted at the beginning of the study, followed by a literature study. A  questionnaire was then developed from findings of literature and exploratory study and used to conduct a survey among 200 healthcare professionals and managers in Limpopo Province. Permission and ethical clearance was obtained from Tshwane University Technology and Limpopo Healthcare Department. Structural Equation Modeling using AMOS was used to test the hypotheses. Lack of management  support was identified as the biggest challenge whereas, the Acceptance and Use readiness and its sub-components have the strongest ability to predict  preparedness to implement Mobile e-Healthcare. This study has developed and  validated a Framework for assessing a healthcare facility readiness to implement a Mobile e-Healthcare system which is the gap identified from literature. Policy and decision makers will be able to use the developed model as an important reference when a healthcare facility is implementing a Mobile e-Healthcare systemKeywords: Mobile, e-Healthcare, Readiness, Assessment, mHealth, and Issues and challenges
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Adrenocortical response to competitive athletics in students from a
           Nigerian Tertiary Institution

    • Authors: O.E. Osayande, E.E. Ogbonmwan, O.K. Adebayo
      Abstract: Exercise is a voluntary stressor. It activates the sympathetic nervous system  (SNS) as well as hypothalamic-pituitary-adrenal (HPA) axis, which results in an increase of cortisol secretion. Very little is known however about adrenocortical  response at basal state, just before the onset of exercise (pre-exercise) and  immediately after exercise (post-exercise) with relationship to gender especially in this environment. This study is therefore aimed at investigating the cortisol  response during competitive athletics in male and female athletes during the basal  state, just before the exercise commences, and after the exercise. Twenty male and female athletes (22.13 ± 3.37 years) participated in this study. They were divided  into two groups based on gender. Each Group consisted of 10 athletes who  participated in a 30-minute competitive sprint round the track. Blood samples were taken at basal states, pre-exercise and post-exercise states for the analysis of  cortisol using an ELISA cortisol kit. From the results, the pre-exercise and post  exercise cortisol levels were significantly higher than at the basal state in both male and female athletes. Also, there was no significant difference (p>0.05) in the  cortisol level during basal and pre-exercise states between the male and female  athletes. The female athletes had a significant (p<0.05) higher cortisol level in the post-exercise state compared to male athletes. conclusively, exercise increases cortisol levels during the anticipation state of exercise and after strenuous exercise in male and female athletes and the female athletes’ hypothalamic pituitary adrenal axis maybe more responsive in the secretion of cortisol during strenuous exercise hence the greater increase seen.
      Keywords: Adrenocortical response, Athletes, Competitive athletics, Nigerians
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Computer-related vision problems in Osogbo, south-western Nigeria

    • Authors: O.U. Kolawole, R.A. Iyanda, M.A. Isawumi
      Abstract: Widespread use of computers for office work and e-learning has resulted in  increased visual demands among computer users. The increased visual demands  have led to development of ocular complaints and discomfort among users. The  objective of this study is to determine the prevalence of computer related eye  problems and their associations among computer users in Osogbo, South Western  Nigeria. A written semi-structured questionnaire was used to collect information on computer related symptoms among bankers, office workers and students in Osogbo, South Western, Nigeria. A total of 416 respondents completed and returned the  questionnaire. All the respondents had at least one computer related symptom. The  most prevalent symptom was neck and shoulder pain which was reported by 62%  computer users. Backache and headache were reported by 60.8% and 58.4% of the respondents respectively. Blurring of vision while working on the computer was the commonest symptom that stopped respondents while using computers. No  significant association was found between symptom scores and gender, duration of  computer use, type of computer screens, and use of screen filter. Symptom scores  were significantly related to presence of pre-existing eye problems. Symptoms were also related to ergonomically inappropriate workstation environments of  respondents. Computer related vision symptoms occur frequently among computer users in South Western Nigeria. Improvement in workstation environments of  computer users and treatment of pre-existing eye problems require attention to prevent occurrence of epidemics of computer related visual problems in this part of the world.
      Keywords: Asthenopia, Computer use, workplace, accommodation, Nigeria
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Six-lead electrocardiographic studies of the pigeon (Columba
           livia
    ) in Nigeria

    • Authors: T.O. Omóbòwálé, O.O. Esan, O.A. Adejumobi, O.A. Oladele
      Abstract: In this study, the normal electrocardiogram of apparently normal, conscious pigeons was described. Standard bipolar and augmented unipolar limb leads were recorded in a total of apparently healthy 30 pigeons. Waveforms were analyzed in all the leads at 50 mm/s and 10 mm/mV. P-wave was monophasic and positive in leads I, II, III, aVL and aVF but negative in aVR. Heart rate ranged from 205 to 342 beats/min with a mean (± SD) of 276.0±42.9 beats/min. The MEA ranged between -99 to -90 degrees. The predominant QRS pattern in lead in lead I was rs while the rS was predominant in leads II, III and aVR. The r and Qr morphologies were observed in leads aVF and aVL  respectively. ST slurring was found in all the leads. The ECG values and patterns  recorded in these clinically healthy pigeons will facilitate better understanding of ECG changes that are seen in diseases and are expected to provide a comparison to aid clinical diagnosis
      Keywords: Electrocardiogram, Pigeons, Limb leads.
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Antinociceptive and anti-inflammatory properties of a polyherbal extract
           of Plumbago zeylinica and Capsicum frutescens in rodents

    • Authors: A. Alabi, A.M. Ajayi, W.E. Olooto, C. Emegoakor, O. Oladunjoye, Y. Obikoya
      Abstract: The aim of the present study is to evaluate the anti-nociceptive and  anti-inflammatory properties of an extract of a polyherbal mixture containing the  leaves and roots of Plumbago zeylinica and fruits of Capsicum frutescens. Acute  toxicity effect of WAP was evaluated in mice. The antinociceptive and  anti-inflammatory activities of WAP (100–400 mg/kg) were investigated in hot  plate, acetic acid-induced writhing, carrageenan-induced paw oedema and air pouch  models. No death was recorded when WAP was administered at a dose of 2000  mg/kg. Oral treatment with WAP elicited inhibitory activity in hot plate test.  Abdominal writhing was significantly reduced by WAP at 100, 200 and 400 mg/kg  (54.5 ± 1.6, 20.0 ± 7.4, 38.4 ± 4.8) as compared with the control group (71.0 ±  2.6). Carrageenan-induced oedema formation was significantly (p < 0.05) reduced  at WAP (100, 200, and 400 mg/kg) by 23.5, 27.3 and 31.4%, respectively, and by reference to indomethacin (10 mg/kg, 31.2%). WAP (200 and 400 mg/kg)  significantly reduced exudate volume (37.2 and 44.1%), protein (42.0 and 54.1%),  total leucocytes (59.1 and 60.2) and neutrophils count (57.3 and 58.0%) in the  carrageenan-induced air pouch in rats. Similarly, WAP treated animals showed  reduced nitrites and malondialdehyde levels and increased glutathione levels.  Furthermore, WAP (400 mg/kg) nether affected locomotory activity nor induced gastric lesion in mice. The results of this study revealed that extract of a polyherbal mixture containing the leaves and roots of Plumbago zeylinica and fruits of  Capsicum frutescens possesses anti-noiceptive and anti-inflammatory activity.Keywords: Polyherbal, Plumbago zeylinica, Capsicum frutescens, inflammation, rats
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • Whey protein concentrate and dexamethasone protected rat cerebellum from
           gamma-radiation injury

    • Authors: O.A. Onatola, O. Owoeye, T.N. Elumelu, M.T. Shokunbi, O.A. Malomo
      Abstract: The possible radioprotective effect of Immunocal® (whey protein]) supplement and dexamethasone on gamma-irradiated cerebellar tissue of Wistar rat was  investigated in this study. Forty male albino rats were acclimatized and randomized  into four groups of 10 animals each. Group I rats served as control; Group II:  received 2.5 Gy of gamma-radiation; Group III: received Immunocal® (286mg/kg)  for 14 days, then 2.5 Gy gamma rays on day15 of experiment; Group IV: received  dexamethasone (1mg/kg) i.p daily for 3 days, then 2.5 Gy gamma rays. All rats were euthanized 14 days post-irradiation. Rat brains were fixed in 10% formalin,  processed with routine paraffin wax techniques and stained with Haematoxylin and  Eosin. Histomorphometric studies showed that radiation significantly (p< 0.05)  reduced the thickness of both the molecular and granular layers of the cerebellum  when compared with the control group. This reduction was significantly (p< 0.05)  increased in animals pretreated with Immunocal® and dexamethasone before  irradiation. The densities of the Purkinje and outer stellate cells were significantly  (p< 0.05) reduced in the irradiated animals compared with the control. The Purkinje cells and outer stellate cells were significantly increased (p< 0.05) in animals of  Radiation + Immunocal® and Radiation + Dexamethasone groups relative to the  radiation group. In conclusion, data from the present study showed that  pre-treatment with Immunocal® and dexamethasone before exposure to a single dose of 2 Gy of gamma radiation on the 15th day of the experiment, protected rat’s cerebellum from gross and histological alterations from radiation injury.
      Keywords: Radioprotection, Immunocal®, Dexamethasone, Cerebellum, Purkinje cells
      PubDate: 2017-12-05
      Issue No: Vol. 20, No. 3 (2017)
       
  • HLA-A alleles differentially associate with severity to Plasmodium
           falciparum malaria infection in Ibadan, Nigeria

    • Authors: S.A Ademola
      Abstract: Human Leukocyte Antigen (HLA), particularly HLA-B and class II alleles have been differentially associated with disease outcomes in different populations following infection with the malaria Plasmodium falciparum. However, the effect of HLA-A on malaria infection and/or disease is not fully understood. Recently, HLA-A alleles have been suggested to play a role in the outcome of P. falciparum malaria infection in a Malian study. Herein, we investigated the association between HLA-A alleles and the outcome of malaria infection in children in Ibadan southwest Nigeria. HLA-A genotyping was performed on 393 children samples (DNA) using the  sequence-based method. We compared genotype and allele frequencies data  obtained from these Nigerian children; 176 with asymptomatic malaria infection  (controls), 124 with uncomplicated malaria and 93 children with severe malaria (51 severe malarial anaemia and 42 cerebral malaria). We found a high frequency of  HLA-A*36:01 (13.5%) in the entire studied population and also confirmed the high frequency of a previously reported allele of African origin (HLA-A*30:01). After  adjusting for age and parasite density, we found a significant association between HLA-A*20:01:01 (OR = 3.19, p < 0.001) and susceptibility to severe malarial  anaemia. We also found significant associations between HLA-A* 29:02:01 (OR = 7.26, p = 0.008) and A* 66:02 (Or = 4.19, p = 0.03) and susceptibility to cerebral malaria. Our findings suggest that HLA-A alleles play a role in the outcome of  malaria in children in Ibadan. These findings may help elucidate the molecular  background of malaria resistance in the study population.Keywords: Severe malaria, HLA-A, Ibadan, children
      Issue No: Vol. 20, No. 3
       
 
 
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